HNRNPA3P3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.57789982
2chaperone-mediated protein transport (GO:0072321)5.38577617
3mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.97301984
4ATP synthesis coupled proton transport (GO:0015986)4.95082815
5energy coupled proton transport, down electrochemical gradient (GO:0015985)4.95082815
6rRNA modification (GO:0000154)4.79592584
7rRNA methylation (GO:0031167)4.60676591
8respiratory electron transport chain (GO:0022904)4.59722559
9proteasome assembly (GO:0043248)4.53265980
10electron transport chain (GO:0022900)4.51098913
11establishment of protein localization to mitochondrial membrane (GO:0090151)4.38308692
12sequestering of actin monomers (GO:0042989)4.36334907
13maturation of SSU-rRNA (GO:0030490)4.24461616
14protein neddylation (GO:0045116)4.23562400
15DNA deamination (GO:0045006)4.17907689
16transcription elongation from RNA polymerase III promoter (GO:0006385)4.16474381
17termination of RNA polymerase III transcription (GO:0006386)4.16474381
18respiratory chain complex IV assembly (GO:0008535)4.14911943
19exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 4.05639457
20viral transcription (GO:0019083)3.99272548
21translational termination (GO:0006415)3.98147771
22ribosomal small subunit biogenesis (GO:0042274)3.97760215
23nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.97015097
24cotranslational protein targeting to membrane (GO:0006613)3.92673761
25protein targeting to ER (GO:0045047)3.91142769
26SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.88472415
27protein complex biogenesis (GO:0070271)3.82710917
28mitochondrial respiratory chain complex assembly (GO:0033108)3.79065817
29establishment of protein localization to endoplasmic reticulum (GO:0072599)3.73960478
30water-soluble vitamin biosynthetic process (GO:0042364)3.70980038
31protein localization to endoplasmic reticulum (GO:0070972)3.65996105
32establishment of integrated proviral latency (GO:0075713)3.65483691
33regulation of mitochondrial translation (GO:0070129)3.65189519
34mitochondrial respiratory chain complex I assembly (GO:0032981)3.62282475
35NADH dehydrogenase complex assembly (GO:0010257)3.62282475
36mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.62282475
37regulation of gene silencing by RNA (GO:0060966)3.44172319
38regulation of posttranscriptional gene silencing (GO:0060147)3.44172319
39regulation of gene silencing by miRNA (GO:0060964)3.44172319
40negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.43532895
41regulation of mitotic spindle checkpoint (GO:1903504)3.43186542
42regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.43186542
43translation (GO:0006412)3.39751404
44DNA damage response, detection of DNA damage (GO:0042769)3.37638947
45translational elongation (GO:0006414)3.37158360
46spliceosomal snRNP assembly (GO:0000387)3.31451417
47cytochrome complex assembly (GO:0017004)3.27858448
48regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.19620211
49anterograde synaptic vesicle transport (GO:0048490)3.13439952
50chromatin remodeling at centromere (GO:0031055)3.13207393
51DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.11179649
52viral life cycle (GO:0019058)3.08804989
53rRNA processing (GO:0006364)3.07990419
54regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.07516233
55translational initiation (GO:0006413)3.06865789
56pseudouridine synthesis (GO:0001522)3.06422733
57epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.06373658
58signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.05932416
59signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.05932416
60signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.05932416
61rRNA metabolic process (GO:0016072)3.05710754
62protein targeting to mitochondrion (GO:0006626)3.04960564
63L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.04413412
64ribosomal small subunit assembly (GO:0000028)3.02945449
65negative regulation of ligase activity (GO:0051352)3.02817736
66negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.02817736
67hydrogen ion transmembrane transport (GO:1902600)3.01096344
68intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.00943118
69signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.00943118
70cellular protein complex disassembly (GO:0043624)3.00573348
71transcription from mitochondrial promoter (GO:0006390)2.99796117
72positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.98649190
73nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.96527561
74establishment of protein localization to mitochondrion (GO:0072655)2.92312082
75histone mRNA metabolic process (GO:0008334)2.91625564
76signal transduction involved in DNA integrity checkpoint (GO:0072401)2.91092267
77signal transduction involved in DNA damage checkpoint (GO:0072422)2.91092267
78epithelial cilium movement (GO:0003351)2.89467329
79amino acid salvage (GO:0043102)2.89217880
80L-methionine salvage (GO:0071267)2.89217880
81L-methionine biosynthetic process (GO:0071265)2.89217880
82DNA double-strand break processing (GO:0000729)2.89008664
83signal transduction involved in cell cycle checkpoint (GO:0072395)2.88778066
84histone H4-K12 acetylation (GO:0043983)2.87734696
85CENP-A containing nucleosome assembly (GO:0034080)2.86660218
86establishment of viral latency (GO:0019043)2.84695994
87peptidyl-histidine modification (GO:0018202)2.80719447
88anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.79035928
89regulation of helicase activity (GO:0051095)2.78352497
90ribosomal large subunit biogenesis (GO:0042273)2.78223046
91inner mitochondrial membrane organization (GO:0007007)2.78121986
92ATP biosynthetic process (GO:0006754)2.76729096
93protein localization to mitochondrion (GO:0070585)2.76278835
94proton transport (GO:0015992)2.75445316
95regulation of cellular amino acid metabolic process (GO:0006521)2.74478098
96RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.74335816
97tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.74335816
98tRNA processing (GO:0008033)2.72141270
99oxidative phosphorylation (GO:0006119)2.72014908
100hydrogen transport (GO:0006818)2.71924418

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.98607848
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.33693255
3EST1_17652178_ChIP-ChIP_JURKAT_Human4.12441156
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.07615400
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.17506811
6HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.14173243
7ETS1_20019798_ChIP-Seq_JURKAT_Human2.99387925
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.87528198
9MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.68073044
10SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.66498804
11CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.59294799
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.57968139
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.47716738
14GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.46843781
15ELK1_19687146_ChIP-ChIP_HELA_Human2.45944018
16VDR_22108803_ChIP-Seq_LS180_Human2.44001732
17PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.40796751
18FOXP3_21729870_ChIP-Seq_TREG_Human2.40284840
19IGF1R_20145208_ChIP-Seq_DFB_Human2.37378376
20VDR_23849224_ChIP-Seq_CD4+_Human2.34689844
21E2F4_17652178_ChIP-ChIP_JURKAT_Human2.32917220
22YY1_21170310_ChIP-Seq_MESCs_Mouse2.32094155
23DMRT1_21621532_ChIP-ChIP_FETAL_Ovary2.31949877
24NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.12471122
25TTF2_22483619_ChIP-Seq_HELA_Human2.05642833
26BP1_19119308_ChIP-ChIP_Hs578T_Human2.04872176
27MYC_18940864_ChIP-ChIP_HL60_Human1.98736698
28MYC_19030024_ChIP-ChIP_MESCs_Mouse1.97599665
29MYC_18358816_ChIP-ChIP_MESCs_Mouse1.92902325
30POU5F1_16153702_ChIP-ChIP_HESCs_Human1.86879592
31GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.81737207
32SRF_21415370_ChIP-Seq_HL-1_Mouse1.78930855
33PADI4_21655091_ChIP-ChIP_MCF-7_Human1.73776994
34ELF1_17652178_ChIP-ChIP_JURKAT_Human1.72770770
35NOTCH1_21737748_ChIP-Seq_TLL_Human1.71454235
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.69791413
37FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.68919120
38YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.63080105
39EWS_26573619_Chip-Seq_HEK293_Human1.63072466
40FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.58959491
41SOX2_16153702_ChIP-ChIP_HESCs_Human1.52940346
42TAF15_26573619_Chip-Seq_HEK293_Human1.47426432
43CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.46672500
44XRN2_22483619_ChIP-Seq_HELA_Human1.46539766
45MYC_19079543_ChIP-ChIP_MESCs_Mouse1.43180367
46ZNF274_21170338_ChIP-Seq_K562_Hela1.37891957
47FUS_26573619_Chip-Seq_HEK293_Human1.37077298
48DCP1A_22483619_ChIP-Seq_HELA_Human1.33599501
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.33376991
50E2F1_18555785_ChIP-Seq_MESCs_Mouse1.33062894
51GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.32582539
52ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.27337175
53GABP_19822575_ChIP-Seq_HepG2_Human1.26791300
54NANOG_16153702_ChIP-ChIP_HESCs_Human1.26370145
55EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.26210886
56ZFP57_27257070_Chip-Seq_ESCs_Mouse1.17501826
57FLI1_27457419_Chip-Seq_LIVER_Mouse1.17388279
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.16653701
59PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.16630661
60MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.15211761
61NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.12057580
62ELK1_22589737_ChIP-Seq_MCF10A_Human1.11381808
63TP53_22573176_ChIP-Seq_HFKS_Human1.09176730
64CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.08917778
65SOX2_18555785_ChIP-Seq_MESCs_Mouse1.08728194
66MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.08724892
67ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.06338901
68EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.05871131
69NELFA_20434984_ChIP-Seq_ESCs_Mouse1.05554479
70AUTS2_25519132_ChIP-Seq_293T-REX_Human1.05262512
71E2F7_22180533_ChIP-Seq_HELA_Human1.04280047
72TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03437364
73ERG_20517297_ChIP-Seq_VCAP_Human1.02793753
74CBP_20019798_ChIP-Seq_JUKART_Human1.01626833
75IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01626833
76CIITA_25753668_ChIP-Seq_RAJI_Human1.00583095
77TP63_19390658_ChIP-ChIP_HaCaT_Human0.99850952
78GATA3_21878914_ChIP-Seq_MCF-7_Human0.99473512
79CTBP1_25329375_ChIP-Seq_LNCAP_Human0.98747697
80POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.96674995
81POU3F2_20337985_ChIP-ChIP_501MEL_Human0.94338806
82KDM5A_27292631_Chip-Seq_BREAST_Human0.93176414
83CTBP2_25329375_ChIP-Seq_LNCAP_Human0.93063814
84ER_23166858_ChIP-Seq_MCF-7_Human0.92851789
85GBX2_23144817_ChIP-Seq_PC3_Human0.91695240
86HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.91336366
87FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.91152757
88P300_19829295_ChIP-Seq_ESCs_Human0.89885543
89CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.88748410
90AR_20517297_ChIP-Seq_VCAP_Human0.88037168
91EZH2_22144423_ChIP-Seq_EOC_Human0.87264648
92NANOG_18555785_ChIP-Seq_MESCs_Mouse0.86916722
93NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.85596103
94SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.83732534
95NCOR_22424771_ChIP-Seq_293T_Human0.80875660
96IRF1_19129219_ChIP-ChIP_H3396_Human0.79719470
97STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.78858985
98RBPJ_21746931_ChIP-Seq_IB4_Human0.78700496
99BCAT_22108803_ChIP-Seq_LS180_Human0.76092299
100MYCN_18555785_ChIP-Seq_MESCs_Mouse0.75511782

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode6.42460243
2MP0009379_abnormal_foot_pigmentation3.55340266
3MP0008789_abnormal_olfactory_epithelium3.26529679
4MP0001188_hyperpigmentation2.92918545
5MP0003136_yellow_coat_color2.76516652
6MP0002938_white_spotting2.73432640
7MP0003878_abnormal_ear_physiology2.72157070
8MP0005377_hearing/vestibular/ear_phenot2.72157070
9MP0002277_abnormal_respiratory_mucosa2.51204946
10MP0004885_abnormal_endolymph2.43232886
11MP0002736_abnormal_nociception_after2.33785393
12MP0005394_taste/olfaction_phenotype2.30269758
13MP0005499_abnormal_olfactory_system2.30269758
14MP0003195_calcinosis2.17384415
15MP0002234_abnormal_pharynx_morphology2.01942556
16MP0003693_abnormal_embryo_hatching1.98044523
17MP0000372_irregular_coat_pigmentation1.96160994
18MP0001968_abnormal_touch/_nociception1.94753135
19MP0005084_abnormal_gallbladder_morpholo1.92964861
20MP0006072_abnormal_retinal_apoptosis1.85989274
21MP0003786_premature_aging1.81985113
22MP0002138_abnormal_hepatobiliary_system1.81901925
23MP0001293_anophthalmia1.78977606
24MP0008877_abnormal_DNA_methylation1.75503710
25MP0004133_heterotaxia1.65124678
26MP0002139_abnormal_hepatobiliary_system1.64840513
27MP0008058_abnormal_DNA_repair1.63690624
28MP0008995_early_reproductive_senescence1.60759259
29MP0004957_abnormal_blastocyst_morpholog1.58952614
30MP0005671_abnormal_response_to1.57954191
31MP0003718_maternal_effect1.56300190
32MP0001485_abnormal_pinna_reflex1.55700499
33MP0004147_increased_porphyrin_level1.55541375
34MP0003186_abnormal_redox_activity1.53974857
35MP0003567_abnormal_fetal_cardiomyocyte1.52254464
36MP0010094_abnormal_chromosome_stability1.48488235
37MP0000569_abnormal_digit_pigmentation1.42076900
38MP0003787_abnormal_imprinting1.37530546
39MP0000631_abnormal_neuroendocrine_gland1.35930142
40MP0005174_abnormal_tail_pigmentation1.35824516
41MP0004185_abnormal_adipocyte_glucose1.34021452
42MP0000049_abnormal_middle_ear1.29953911
43MP0005551_abnormal_eye_electrophysiolog1.29484605
44MP0003011_delayed_dark_adaptation1.26764128
45MP0009697_abnormal_copulation1.22224624
46MP0005408_hypopigmentation1.17327946
47MP0001727_abnormal_embryo_implantation1.13151397
48MP0003283_abnormal_digestive_organ1.13135960
49MP0003121_genomic_imprinting1.08002975
50MP0006036_abnormal_mitochondrial_physio1.06637650
51MP0002638_abnormal_pupillary_reflex1.04298224
52MP0003938_abnormal_ear_development1.04240375
53MP0008932_abnormal_embryonic_tissue1.03333972
54MP0004142_abnormal_muscle_tone1.03300278
55MP0001905_abnormal_dopamine_level1.02347456
56MP0006276_abnormal_autonomic_nervous0.97159879
57MP0001324_abnormal_eye_pigmentation0.95027707
58MP0002653_abnormal_ependyma_morphology0.94947022
59MP0005645_abnormal_hypothalamus_physiol0.93264999
60MP0005365_abnormal_bile_salt0.91411688
61MP0002184_abnormal_innervation0.90385300
62MP0001286_abnormal_eye_development0.89113378
63MP0001984_abnormal_olfaction0.88969929
64MP0000566_synostosis0.86423066
65MP0002006_tumorigenesis0.86175291
66MP0002095_abnormal_skin_pigmentation0.85482607
67MP0000778_abnormal_nervous_system0.85034540
68MP0009745_abnormal_behavioral_response0.84641589
69MP0005195_abnormal_posterior_eye0.83291980
70MP0002735_abnormal_chemical_nociception0.83272389
71MP0003880_abnormal_central_pattern0.81823505
72MP0003646_muscle_fatigue0.81258672
73MP0003077_abnormal_cell_cycle0.80787710
74MP0002067_abnormal_sensory_capabilities0.80309024
75MP0005389_reproductive_system_phenotype0.79718848
76MP0002233_abnormal_nose_morphology0.79448074
77MP0005253_abnormal_eye_physiology0.78590247
78MP0001919_abnormal_reproductive_system0.75945245
79MP0005395_other_phenotype0.75655947
80MP0003941_abnormal_skin_development0.75540816
81MP0003111_abnormal_nucleus_morphology0.75431060
82MP0002177_abnormal_outer_ear0.72221391
83MP0004742_abnormal_vestibular_system0.72028953
84MP0002102_abnormal_ear_morphology0.71907671
85MP0008875_abnormal_xenobiotic_pharmacok0.71860969
86MP0008872_abnormal_physiological_respon0.71779411
87MP0000026_abnormal_inner_ear0.71635961
88MP0006035_abnormal_mitochondrial_morpho0.70192631
89MP0001529_abnormal_vocalization0.69916410
90MP0002751_abnormal_autonomic_nervous0.68413470
91MP0002733_abnormal_thermal_nociception0.67296770
92MP0000579_abnormal_nail_morphology0.66134917
93MP0005075_abnormal_melanosome_morpholog0.65967873
94MP0003252_abnormal_bile_duct0.65789841
95MP0002210_abnormal_sex_determination0.65738602
96MP0002272_abnormal_nervous_system0.65702365
97MP0009333_abnormal_splenocyte_physiolog0.65625675
98MP0003119_abnormal_digestive_system0.63933647
99MP0002752_abnormal_somatic_nervous0.63592690
100MP0003937_abnormal_limbs/digits/tail_de0.62325437

Predicted human phenotypes

RankGene SetZ-score
1Increased hepatocellular lipid droplets (HP:0006565)4.77673644
2Acute necrotizing encephalopathy (HP:0006965)4.72241222
33-Methylglutaconic aciduria (HP:0003535)4.62503015
4Mitochondrial inheritance (HP:0001427)4.32579514
5Abnormal mitochondria in muscle tissue (HP:0008316)4.23695843
6Lipid accumulation in hepatocytes (HP:0006561)4.23350324
7Increased CSF lactate (HP:0002490)3.88329045
8Acute encephalopathy (HP:0006846)3.85754899
9Progressive macrocephaly (HP:0004481)3.83746671
10Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.73166133
11Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.57806975
12Dynein arm defect of respiratory motile cilia (HP:0012255)3.57105085
13Absent/shortened dynein arms (HP:0200106)3.57105085
14Renal Fanconi syndrome (HP:0001994)3.49386368
15Reticulocytopenia (HP:0001896)3.28900697
16Hepatocellular necrosis (HP:0001404)3.24795066
17Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.17941393
18Congenital, generalized hypertrichosis (HP:0004540)3.13672723
19Increased intramyocellular lipid droplets (HP:0012240)3.10691317
20Hepatic necrosis (HP:0002605)3.07884508
21Adrenal hypoplasia (HP:0000835)2.90055345
22Septo-optic dysplasia (HP:0100842)2.89856141
23Cerebral edema (HP:0002181)2.85305457
24Chronic bronchitis (HP:0004469)2.84500342
25Abnormal number of incisors (HP:0011064)2.83866264
26Pancreatic fibrosis (HP:0100732)2.77860956
27Exertional dyspnea (HP:0002875)2.74817853
28Abnormal number of erythroid precursors (HP:0012131)2.66381031
29Congenital stationary night blindness (HP:0007642)2.65778147
30Increased serum lactate (HP:0002151)2.60705347
31Parakeratosis (HP:0001036)2.54673514
32Respiratory difficulties (HP:0002880)2.51661292
33Macrocytic anemia (HP:0001972)2.50591282
34Pancreatic cysts (HP:0001737)2.49275758
35Hyperphosphaturia (HP:0003109)2.48963597
36Abnormality of cells of the erythroid lineage (HP:0012130)2.46897410
37True hermaphroditism (HP:0010459)2.46118240
38Glycosuria (HP:0003076)2.42970838
39Abnormality of urine glucose concentration (HP:0011016)2.42970838
40Optic disc pallor (HP:0000543)2.42822600
41Increased muscle lipid content (HP:0009058)2.41538909
42Type II lissencephaly (HP:0007260)2.40551025
43Pendular nystagmus (HP:0012043)2.33892417
44Abnormality of renal resorption (HP:0011038)2.32462416
45Lactic acidosis (HP:0003128)2.30379480
46Abnormality of midbrain morphology (HP:0002418)2.29820491
47Molar tooth sign on MRI (HP:0002419)2.29820491
48Duplicated collecting system (HP:0000081)2.29503429
49Abnormality of placental membranes (HP:0011409)2.28727461
50Amniotic constriction ring (HP:0009775)2.28727461
51Exercise intolerance (HP:0003546)2.28112297
52Abnormal respiratory motile cilium physiology (HP:0012261)2.27661110
53Nephronophthisis (HP:0000090)2.23082294
54Abnormality of the renal collecting system (HP:0004742)2.20073012
55Oral leukoplakia (HP:0002745)2.19653245
56Methylmalonic acidemia (HP:0002912)2.17649605
57Lethargy (HP:0001254)2.17175178
58Constricted visual fields (HP:0001133)2.14638940
59Abnormal respiratory epithelium morphology (HP:0012253)2.12982718
60Abnormal respiratory motile cilium morphology (HP:0005938)2.12982718
61Methylmalonic aciduria (HP:0012120)2.10673861
62Leukodystrophy (HP:0002415)2.10248938
63IgG deficiency (HP:0004315)2.07364978
64Homocystinuria (HP:0002156)2.06354907
65Abnormality of homocysteine metabolism (HP:0010919)2.06354907
66Abnormal biliary tract physiology (HP:0012439)2.05698011
67Bile duct proliferation (HP:0001408)2.05698011
68Respiratory failure (HP:0002878)2.04885550
69Rib fusion (HP:0000902)2.01345644
70Abnormality of DNA repair (HP:0003254)1.99443391
71Absent septum pellucidum (HP:0001331)1.97501971
72Aplastic anemia (HP:0001915)1.97202388
73Abnormality of T cell number (HP:0011839)1.94855080
74Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.93281611
75Abnormality of the pons (HP:0007361)1.91550903
76Severe combined immunodeficiency (HP:0004430)1.89000483
77Severe visual impairment (HP:0001141)1.87508603
78Abnormality of the metopic suture (HP:0005556)1.86974357
79Aplasia/Hypoplasia of the tongue (HP:0010295)1.83042524
80Abnormal ciliary motility (HP:0012262)1.82403079
81Maternal diabetes (HP:0009800)1.81530937
82T lymphocytopenia (HP:0005403)1.81209211
83Abnormality of chromosome stability (HP:0003220)1.81206010
84Aplasia/Hypoplasia of the uvula (HP:0010293)1.78235769
85Renal cortical cysts (HP:0000803)1.78134741
86Papilledema (HP:0001085)1.76440310
87Esophageal atresia (HP:0002032)1.75696056
88Sclerocornea (HP:0000647)1.75480900
89Optic nerve hypoplasia (HP:0000609)1.74549247
90Abnormal urine phosphate concentration (HP:0012599)1.74366999
91Hypoplasia of the uterus (HP:0000013)1.73172929
92Meckel diverticulum (HP:0002245)1.72084485
93Absent thumb (HP:0009777)1.72016853
94Abnormal lung lobation (HP:0002101)1.71948779
95Abnormal pupillary function (HP:0007686)1.71652139
96Absent rod-and cone-mediated responses on ERG (HP:0007688)1.69891556
97Decreased electroretinogram (ERG) amplitude (HP:0000654)1.69524861
98Holoprosencephaly (HP:0001360)1.68713024
99Large for gestational age (HP:0001520)1.67743963
100Ectopic kidney (HP:0000086)1.67222370

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.83159269
2TXK4.33136050
3CDK193.73072242
4MAP4K23.49726023
5NME13.22826340
6CDC72.74348875
7DYRK22.68241547
8NUAK12.33188465
9TLK12.28491135
10ZAK2.18842485
11MAP3K122.11425683
12BUB12.01139674
13STK161.89539334
14VRK11.85718416
15GRK11.76006271
16TAF11.61188999
17MST41.51096495
18MKNK11.46279973
19ADRBK21.44428108
20BCKDK1.39638423
21NME21.36979890
22TTK1.30439119
23ITK1.24386045
24PINK11.21045474
25MKNK21.20105800
26NEK11.18801059
27SRPK11.17410185
28TIE11.17210041
29CAMK1D1.16746790
30WNK41.15899607
31KDR1.14689814
32PASK1.14013034
33MAP4K11.13525037
34MAPKAPK51.12595068
35DYRK31.12366688
36PLK31.10912538
37OXSR11.07069531
38TSSK61.06297182
39CSNK1G31.04339679
40WNK31.02171202
41CAMK1G1.00948184
42CSNK1G11.00276289
43BRSK20.99278892
44WEE10.95156020
45PBK0.91213257
46CSNK1G20.90603097
47TEC0.89813247
48MARK30.88003732
49CSNK1A1L0.87212901
50PRKCQ0.83303149
51TYRO30.83277437
52ALK0.83255543
53PLK10.81674652
54NEK20.75777323
55EIF2AK10.74391056
56PIK3CG0.71616387
57MAP3K110.69038560
58AURKB0.68973961
59EPHA30.62837266
60GRK50.61119832
61CHEK20.61049583
62CSNK2A20.59362643
63PIM10.59022389
64AURKA0.57215230
65IRAK10.56792485
66PRKCE0.53946331
67PLK40.53620839
68CDK30.53246212
69CSNK2A10.52958935
70ATR0.50512314
71ABL20.49184043
72CSNK1A10.48969708
73ERBB40.48631009
74DAPK10.47547043
75CCNB10.47216461
76EIF2AK30.45737147
77ADRBK10.42058308
78PRKCH0.41388674
79MATK0.40117992
80RPS6KA50.38627653
81CSNK1E0.38367495
82PRKCG0.37864183
83EIF2AK20.37139636
84PRKCI0.36530891
85CAMK2A0.35632882
86PRKACA0.35344070
87CAMK10.34105402
88BCR0.33582174
89BTK0.33334584
90NLK0.32719437
91TESK20.31265397
92PLK20.31119152
93MYLK0.29581751
94CHEK10.29506892
95PNCK0.29476960
96TNIK0.28863229
97EPHB20.27156202
98STK390.26766389
99MAPKAPK30.26654520
100CDK70.26191323

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.18394515
2Oxidative phosphorylation_Homo sapiens_hsa001904.07713537
3Proteasome_Homo sapiens_hsa030503.99439043
4Protein export_Homo sapiens_hsa030603.91409035
5Parkinsons disease_Homo sapiens_hsa050123.64264333
6RNA polymerase_Homo sapiens_hsa030202.93595377
7Homologous recombination_Homo sapiens_hsa034402.63975485
8Huntingtons disease_Homo sapiens_hsa050162.42590206
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.28427837
10Alzheimers disease_Homo sapiens_hsa050102.20734113
11Spliceosome_Homo sapiens_hsa030402.17746032
12Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.09458785
13Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.05915008
14Cardiac muscle contraction_Homo sapiens_hsa042601.88219857
15Folate biosynthesis_Homo sapiens_hsa007901.87206797
16Mismatch repair_Homo sapiens_hsa034301.81403410
17Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.79562511
18Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.73084918
19RNA degradation_Homo sapiens_hsa030181.67751927
20Steroid biosynthesis_Homo sapiens_hsa001001.50612976
21DNA replication_Homo sapiens_hsa030301.49191982
22Basal transcription factors_Homo sapiens_hsa030221.44499965
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.37398923
24Phototransduction_Homo sapiens_hsa047441.34566023
25Non-homologous end-joining_Homo sapiens_hsa034501.33330176
26Linoleic acid metabolism_Homo sapiens_hsa005911.27373857
27Pyrimidine metabolism_Homo sapiens_hsa002401.22994219
28Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.16504185
29RNA transport_Homo sapiens_hsa030131.13748017
30Tryptophan metabolism_Homo sapiens_hsa003801.13398934
31Primary immunodeficiency_Homo sapiens_hsa053401.04871682
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.04328557
33Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.01185902
34alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.01020099
35Base excision repair_Homo sapiens_hsa034101.00060056
36One carbon pool by folate_Homo sapiens_hsa006700.98164099
37Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.98151109
38Chemical carcinogenesis_Homo sapiens_hsa052040.96336686
39Pyruvate metabolism_Homo sapiens_hsa006200.95513510
40Cysteine and methionine metabolism_Homo sapiens_hsa002700.93287469
41Nucleotide excision repair_Homo sapiens_hsa034200.92615511
42Purine metabolism_Homo sapiens_hsa002300.86568326
43Peroxisome_Homo sapiens_hsa041460.84689069
44Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.84476707
45Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.84470375
46Fanconi anemia pathway_Homo sapiens_hsa034600.82534000
47Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.81989523
48Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.81558141
49Sulfur metabolism_Homo sapiens_hsa009200.81310715
50Fatty acid elongation_Homo sapiens_hsa000620.81083206
51Propanoate metabolism_Homo sapiens_hsa006400.80642832
52Nitrogen metabolism_Homo sapiens_hsa009100.77026235
53Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.76194382
54Vitamin digestion and absorption_Homo sapiens_hsa049770.76107537
55Retinol metabolism_Homo sapiens_hsa008300.73126330
56Maturity onset diabetes of the young_Homo sapiens_hsa049500.72951738
57Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.71260595
58Primary bile acid biosynthesis_Homo sapiens_hsa001200.70295000
59SNARE interactions in vesicular transport_Homo sapiens_hsa041300.70178317
60Pentose and glucuronate interconversions_Homo sapiens_hsa000400.69079510
61Butanoate metabolism_Homo sapiens_hsa006500.68968041
62Metabolic pathways_Homo sapiens_hsa011000.68208877
63Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.65032736
64Sulfur relay system_Homo sapiens_hsa041220.62831571
65Autoimmune thyroid disease_Homo sapiens_hsa053200.62755212
66Glutathione metabolism_Homo sapiens_hsa004800.61645818
67Basal cell carcinoma_Homo sapiens_hsa052170.57270813
68beta-Alanine metabolism_Homo sapiens_hsa004100.55079196
69Arachidonic acid metabolism_Homo sapiens_hsa005900.54819237
70Phenylalanine metabolism_Homo sapiens_hsa003600.50378077
71Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.49748087
72Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.48612404
73Steroid hormone biosynthesis_Homo sapiens_hsa001400.48551769
74Caffeine metabolism_Homo sapiens_hsa002320.45621946
75p53 signaling pathway_Homo sapiens_hsa041150.45279013
76Selenocompound metabolism_Homo sapiens_hsa004500.43174636
77mRNA surveillance pathway_Homo sapiens_hsa030150.42517884
78Allograft rejection_Homo sapiens_hsa053300.42017808
79Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.41794425
80Graft-versus-host disease_Homo sapiens_hsa053320.41771760
81Rheumatoid arthritis_Homo sapiens_hsa053230.40606773
82Collecting duct acid secretion_Homo sapiens_hsa049660.40393479
83Regulation of autophagy_Homo sapiens_hsa041400.37428492
84Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.36863146
85Olfactory transduction_Homo sapiens_hsa047400.36568215
86Fat digestion and absorption_Homo sapiens_hsa049750.36477053
87Epstein-Barr virus infection_Homo sapiens_hsa051690.36297909
88Fatty acid degradation_Homo sapiens_hsa000710.33296725
89Nicotine addiction_Homo sapiens_hsa050330.32369963
90Cell cycle_Homo sapiens_hsa041100.32057602
91Type I diabetes mellitus_Homo sapiens_hsa049400.30506541
92Biosynthesis of amino acids_Homo sapiens_hsa012300.29121653
93Intestinal immune network for IgA production_Homo sapiens_hsa046720.27909294
94Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27747851
95Hedgehog signaling pathway_Homo sapiens_hsa043400.27078850
96Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.26117950
97Ether lipid metabolism_Homo sapiens_hsa005650.25529686
98Glycerolipid metabolism_Homo sapiens_hsa005610.25500286
99Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.24767570
100Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.24679859

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »