

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.36991294 |
| 2 | rRNA modification (GO:0000154) | 5.45518680 |
| 3 | rRNA methylation (GO:0031167) | 5.05283787 |
| 4 | proteasome assembly (GO:0043248) | 4.47652102 |
| 5 | purine-containing compound salvage (GO:0043101) | 4.25275336 |
| 6 | IMP biosynthetic process (GO:0006188) | 4.07040381 |
| 7 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.93815531 |
| 8 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.85543144 |
| 9 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.84838926 |
| 10 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.82192580 |
| 11 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.80411016 |
| 12 | ATP synthesis coupled proton transport (GO:0015986) | 3.80339942 |
| 13 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.80339942 |
| 14 | GTP biosynthetic process (GO:0006183) | 3.70169592 |
| 15 | ribosomal large subunit biogenesis (GO:0042273) | 3.67607030 |
| 16 | protein complex biogenesis (GO:0070271) | 3.64890833 |
| 17 | GMP metabolic process (GO:0046037) | 3.59266276 |
| 18 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.56421546 |
| 19 | NADH dehydrogenase complex assembly (GO:0010257) | 3.56421546 |
| 20 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.56421546 |
| 21 | purine nucleobase biosynthetic process (GO:0009113) | 3.51267574 |
| 22 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.50714609 |
| 23 | nucleobase biosynthetic process (GO:0046112) | 3.49529574 |
| 24 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.45753652 |
| 25 | pseudouridine synthesis (GO:0001522) | 3.43387908 |
| 26 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.43315533 |
| 27 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.40120360 |
| 28 | negative regulation of B cell apoptotic process (GO:0002903) | 3.39512948 |
| 29 | maturation of 5.8S rRNA (GO:0000460) | 3.37042100 |
| 30 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.35940728 |
| 31 | regulation of regulatory T cell differentiation (GO:0045589) | 3.27944617 |
| 32 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.27468337 |
| 33 | respiratory chain complex IV assembly (GO:0008535) | 3.27250647 |
| 34 | regulation of immunoglobulin secretion (GO:0051023) | 3.26002059 |
| 35 | UTP biosynthetic process (GO:0006228) | 3.25014143 |
| 36 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.24595537 |
| 37 | termination of RNA polymerase III transcription (GO:0006386) | 3.24595537 |
| 38 | IMP metabolic process (GO:0046040) | 3.23319147 |
| 39 | cytidine deamination (GO:0009972) | 3.19704142 |
| 40 | cytidine metabolic process (GO:0046087) | 3.19704142 |
| 41 | cytidine catabolic process (GO:0006216) | 3.19704142 |
| 42 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.19158849 |
| 43 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.19076054 |
| 44 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.19076054 |
| 45 | peptidyl-histidine modification (GO:0018202) | 3.18994279 |
| 46 | L-methionine salvage (GO:0071267) | 3.18842961 |
| 47 | L-methionine biosynthetic process (GO:0071265) | 3.18842961 |
| 48 | amino acid salvage (GO:0043102) | 3.18842961 |
| 49 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.17270480 |
| 50 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.17270480 |
| 51 | isotype switching (GO:0045190) | 3.17270480 |
| 52 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.15369172 |
| 53 | ribosome assembly (GO:0042255) | 3.15323123 |
| 54 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.13201146 |
| 55 | piRNA metabolic process (GO:0034587) | 3.12789113 |
| 56 | DNA damage response, detection of DNA damage (GO:0042769) | 3.12144998 |
| 57 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.10118099 |
| 58 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.09799491 |
| 59 | signal peptide processing (GO:0006465) | 3.08273272 |
| 60 | rRNA processing (GO:0006364) | 3.06735161 |
| 61 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.06111903 |
| 62 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.06111903 |
| 63 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.06111903 |
| 64 | cytochrome complex assembly (GO:0017004) | 3.04633021 |
| 65 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.01788194 |
| 66 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.01788194 |
| 67 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.00171523 |
| 68 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.00171523 |
| 69 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.99892925 |
| 70 | urate metabolic process (GO:0046415) | 2.97712685 |
| 71 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.96223872 |
| 72 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.96223872 |
| 73 | termination of RNA polymerase I transcription (GO:0006363) | 2.93928794 |
| 74 | tRNA processing (GO:0008033) | 2.93324246 |
| 75 | methionine biosynthetic process (GO:0009086) | 2.93187811 |
| 76 | rRNA metabolic process (GO:0016072) | 2.92532497 |
| 77 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.91861045 |
| 78 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.91845171 |
| 79 | cullin deneddylation (GO:0010388) | 2.90399838 |
| 80 | NAD biosynthetic process (GO:0009435) | 2.88650204 |
| 81 | tRNA modification (GO:0006400) | 2.87891699 |
| 82 | UTP metabolic process (GO:0046051) | 2.87635069 |
| 83 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 2.86600721 |
| 84 | protein neddylation (GO:0045116) | 2.85973541 |
| 85 | behavioral response to nicotine (GO:0035095) | 2.85929099 |
| 86 | chaperone-mediated protein transport (GO:0072321) | 2.84639356 |
| 87 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.83355515 |
| 88 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.83355515 |
| 89 | positive regulation of interleukin-17 production (GO:0032740) | 2.83262062 |
| 90 | purine nucleotide salvage (GO:0032261) | 2.79608433 |
| 91 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.78877857 |
| 92 | ribosome biogenesis (GO:0042254) | 2.78611183 |
| 93 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.77751046 |
| 94 | positive regulation of isotype switching (GO:0045830) | 2.77516852 |
| 95 | tRNA metabolic process (GO:0006399) | 2.75885494 |
| 96 | somatic diversification of immunoglobulins (GO:0016445) | 2.75884790 |
| 97 | amino acid activation (GO:0043038) | 2.75248135 |
| 98 | tRNA aminoacylation (GO:0043039) | 2.75248135 |
| 99 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.73395441 |
| 100 | positive regulation of DNA recombination (GO:0045911) | 2.70745774 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.14551520 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.49319791 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.75420425 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.63315185 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.52665655 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.41827840 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.05284065 |
| 8 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.96193239 |
| 9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.88307334 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.87018686 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.79241563 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.46003726 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.43511856 |
| 14 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.35594953 |
| 15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.28106109 |
| 16 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.22880278 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.22176434 |
| 18 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.20419188 |
| 19 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.18037551 |
| 20 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.14318592 |
| 21 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.13841532 |
| 22 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.01869116 |
| 23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.00287134 |
| 24 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.99703836 |
| 25 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.98221942 |
| 26 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.94656927 |
| 27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.93124979 |
| 28 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.92862450 |
| 29 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.89814055 |
| 30 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.86138616 |
| 31 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.82618921 |
| 32 | EWS_26573619_Chip-Seq_HEK293_Human | 1.80881434 |
| 33 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.79547534 |
| 34 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.70706936 |
| 35 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.68100430 |
| 36 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.67067813 |
| 37 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.66880668 |
| 38 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.64154907 |
| 39 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.62964274 |
| 40 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.60293962 |
| 41 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.57583836 |
| 42 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.57392203 |
| 43 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.55778926 |
| 44 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.45550313 |
| 45 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.44066031 |
| 46 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.43352868 |
| 47 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.39302747 |
| 48 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.37255832 |
| 49 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.31577101 |
| 50 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.29330428 |
| 51 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.29330428 |
| 52 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.27509774 |
| 53 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.26979763 |
| 54 | FUS_26573619_Chip-Seq_HEK293_Human | 1.26638995 |
| 55 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.26338327 |
| 56 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.25166262 |
| 57 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.23141464 |
| 58 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.20742166 |
| 59 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.19056179 |
| 60 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.17113086 |
| 61 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.15636108 |
| 62 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13966062 |
| 63 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.11211848 |
| 64 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.09888748 |
| 65 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.08377531 |
| 66 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.07091940 |
| 67 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.07038217 |
| 68 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06249709 |
| 69 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.03198770 |
| 70 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.03198770 |
| 71 | P300_19829295_ChIP-Seq_ESCs_Human | 1.03149307 |
| 72 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.02576405 |
| 73 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.02333325 |
| 74 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.02058732 |
| 75 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.01708738 |
| 76 | AR_20517297_ChIP-Seq_VCAP_Human | 0.99737448 |
| 77 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.98135995 |
| 78 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.96927194 |
| 79 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.96195048 |
| 80 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.96190680 |
| 81 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.96126358 |
| 82 | NCOR_22424771_ChIP-Seq_293T_Human | 0.95571068 |
| 83 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.95453725 |
| 84 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.95204905 |
| 85 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.92776525 |
| 86 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.92757969 |
| 87 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.92165029 |
| 88 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.91243292 |
| 89 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.91061563 |
| 90 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.90704490 |
| 91 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.90682864 |
| 92 | GATA3_26560356_Chip-Seq_TH2_Human | 0.90562329 |
| 93 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.90306747 |
| 94 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.90096734 |
| 95 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.89232549 |
| 96 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.87529604 |
| 97 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87418025 |
| 98 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.87204391 |
| 99 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.86765901 |
| 100 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.86577800 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008058_abnormal_DNA_repair | 3.97080588 |
| 2 | MP0005671_abnormal_response_to | 3.39500314 |
| 3 | MP0003950_abnormal_plasma_membrane | 3.17634833 |
| 4 | MP0002102_abnormal_ear_morphology | 3.08852409 |
| 5 | MP0002254_reproductive_system_inflammat | 3.02020092 |
| 6 | MP0001835_abnormal_antigen_presentation | 2.88026189 |
| 7 | MP0010094_abnormal_chromosome_stability | 2.63903573 |
| 8 | MP0008877_abnormal_DNA_methylation | 2.63198714 |
| 9 | MP0003693_abnormal_embryo_hatching | 2.59418224 |
| 10 | MP0003806_abnormal_nucleotide_metabolis | 2.51387554 |
| 11 | MP0004957_abnormal_blastocyst_morpholog | 2.25389749 |
| 12 | MP0002234_abnormal_pharynx_morphology | 2.19328802 |
| 13 | MP0003195_calcinosis | 2.16994369 |
| 14 | MP0003786_premature_aging | 2.16265413 |
| 15 | MP0003718_maternal_effect | 2.07623070 |
| 16 | MP0004147_increased_porphyrin_level | 2.05389688 |
| 17 | MP0001853_heart_inflammation | 1.90082582 |
| 18 | MP0005551_abnormal_eye_electrophysiolog | 1.89895365 |
| 19 | MP0002736_abnormal_nociception_after | 1.88686278 |
| 20 | MP0008875_abnormal_xenobiotic_pharmacok | 1.86550398 |
| 21 | MP0009333_abnormal_splenocyte_physiolog | 1.79637040 |
| 22 | MP0000372_irregular_coat_pigmentation | 1.79138269 |
| 23 | MP0005645_abnormal_hypothalamus_physiol | 1.77211940 |
| 24 | MP0008057_abnormal_DNA_replication | 1.76490043 |
| 25 | MP0005410_abnormal_fertilization | 1.75195762 |
| 26 | MP0003111_abnormal_nucleus_morphology | 1.74840898 |
| 27 | MP0009697_abnormal_copulation | 1.74050493 |
| 28 | MP0005084_abnormal_gallbladder_morpholo | 1.67562644 |
| 29 | MP0002148_abnormal_hypersensitivity_rea | 1.65149227 |
| 30 | MP0000685_abnormal_immune_system | 1.63716531 |
| 31 | MP0001968_abnormal_touch/_nociception | 1.60076996 |
| 32 | MP0006035_abnormal_mitochondrial_morpho | 1.59391600 |
| 33 | MP0001790_abnormal_immune_system | 1.58991319 |
| 34 | MP0005387_immune_system_phenotype | 1.58991319 |
| 35 | MP0008872_abnormal_physiological_respon | 1.56122207 |
| 36 | MP0006036_abnormal_mitochondrial_physio | 1.48473466 |
| 37 | MP0009785_altered_susceptibility_to | 1.43427308 |
| 38 | MP0002006_tumorigenesis | 1.38839853 |
| 39 | MP0002138_abnormal_hepatobiliary_system | 1.34538280 |
| 40 | MP0003077_abnormal_cell_cycle | 1.32059285 |
| 41 | MP0006292_abnormal_olfactory_placode | 1.30286320 |
| 42 | MP0003011_delayed_dark_adaptation | 1.29799122 |
| 43 | MP0008007_abnormal_cellular_replicative | 1.29254678 |
| 44 | MP0005646_abnormal_pituitary_gland | 1.25462748 |
| 45 | MP0003763_abnormal_thymus_physiology | 1.25333761 |
| 46 | MP0001929_abnormal_gametogenesis | 1.19389122 |
| 47 | MP0010386_abnormal_urinary_bladder | 1.18480040 |
| 48 | MP0002938_white_spotting | 1.18103334 |
| 49 | MP0001919_abnormal_reproductive_system | 1.17659008 |
| 50 | MP0001873_stomach_inflammation | 1.16993444 |
| 51 | MP0002876_abnormal_thyroid_physiology | 1.15520927 |
| 52 | MP0004019_abnormal_vitamin_homeostasis | 1.13662130 |
| 53 | MP0002210_abnormal_sex_determination | 1.11548808 |
| 54 | MP0001764_abnormal_homeostasis | 1.10999745 |
| 55 | MP0003283_abnormal_digestive_organ | 1.09886878 |
| 56 | MP0002277_abnormal_respiratory_mucosa | 1.08957075 |
| 57 | MP0000613_abnormal_salivary_gland | 1.08109740 |
| 58 | MP0004145_abnormal_muscle_electrophysio | 1.07985355 |
| 59 | MP0005000_abnormal_immune_tolerance | 1.05498239 |
| 60 | MP0000604_amyloidosis | 1.03786997 |
| 61 | MP0006072_abnormal_retinal_apoptosis | 1.02688716 |
| 62 | MP0001501_abnormal_sleep_pattern | 1.00418291 |
| 63 | MP0002837_dystrophic_cardiac_calcinosis | 1.00081134 |
| 64 | MP0005389_reproductive_system_phenotype | 0.99402963 |
| 65 | MP0003646_muscle_fatigue | 0.98796567 |
| 66 | MP0001800_abnormal_humoral_immune | 0.98732872 |
| 67 | MP0005253_abnormal_eye_physiology | 0.95403354 |
| 68 | MP0000653_abnormal_sex_gland | 0.95009216 |
| 69 | MP0002751_abnormal_autonomic_nervous | 0.93684991 |
| 70 | MP0005636_abnormal_mineral_homeostasis | 0.93143228 |
| 71 | MP0005332_abnormal_amino_acid | 0.92631645 |
| 72 | MP0001145_abnormal_male_reproductive | 0.91975059 |
| 73 | MP0003698_abnormal_male_reproductive | 0.91794512 |
| 74 | MP0003186_abnormal_redox_activity | 0.91679473 |
| 75 | MP0001986_abnormal_taste_sensitivity | 0.90518402 |
| 76 | MP0008932_abnormal_embryonic_tissue | 0.89864278 |
| 77 | MP0002420_abnormal_adaptive_immunity | 0.88118021 |
| 78 | MP0001819_abnormal_immune_cell | 0.88069304 |
| 79 | MP0004782_abnormal_surfactant_physiolog | 0.87995366 |
| 80 | MP0003866_abnormal_defecation | 0.86970456 |
| 81 | MP0002160_abnormal_reproductive_system | 0.86824970 |
| 82 | MP0002090_abnormal_vision | 0.86704357 |
| 83 | MP0002166_altered_tumor_susceptibility | 0.83316101 |
| 84 | MP0002723_abnormal_immune_serum | 0.82714639 |
| 85 | MP0004142_abnormal_muscle_tone | 0.81842325 |
| 86 | MP0002733_abnormal_thermal_nociception | 0.81793550 |
| 87 | MP0002396_abnormal_hematopoietic_system | 0.81289405 |
| 88 | MP0005310_abnormal_salivary_gland | 0.80685228 |
| 89 | MP0010155_abnormal_intestine_physiology | 0.79641968 |
| 90 | MP0002272_abnormal_nervous_system | 0.79318376 |
| 91 | MP0005395_other_phenotype | 0.78372064 |
| 92 | MP0005377_hearing/vestibular/ear_phenot | 0.77765161 |
| 93 | MP0003878_abnormal_ear_physiology | 0.77765161 |
| 94 | MP0009053_abnormal_anal_canal | 0.77730714 |
| 95 | MP0008995_early_reproductive_senescence | 0.76972449 |
| 96 | MP0002452_abnormal_antigen_presenting | 0.76861095 |
| 97 | MP0002405_respiratory_system_inflammati | 0.76266936 |
| 98 | MP0002282_abnormal_trachea_morphology | 0.75887182 |
| 99 | MP0000358_abnormal_cell_content/ | 0.75166630 |
| 100 | MP0000689_abnormal_spleen_morphology | 0.75118147 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Dyschromatopsia (HP:0007641) | 4.25923244 |
| 2 | Abnormality of T cell physiology (HP:0011840) | 4.03918588 |
| 3 | Testicular atrophy (HP:0000029) | 4.02519993 |
| 4 | 3-Methylglutaconic aciduria (HP:0003535) | 3.98990574 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 3.86713884 |
| 6 | Abnormality of the pons (HP:0007361) | 3.72794174 |
| 7 | Mitochondrial inheritance (HP:0001427) | 3.70049446 |
| 8 | Stomatitis (HP:0010280) | 3.69399177 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.62125181 |
| 10 | Increased CSF lactate (HP:0002490) | 3.61995827 |
| 11 | Prostate neoplasm (HP:0100787) | 3.52233496 |
| 12 | Central scotoma (HP:0000603) | 3.50430413 |
| 13 | Autoimmune thrombocytopenia (HP:0001973) | 3.36715586 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.27401109 |
| 15 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.25814453 |
| 16 | Acute encephalopathy (HP:0006846) | 3.25192893 |
| 17 | Autoimmune hemolytic anemia (HP:0001890) | 3.11550501 |
| 18 | Progressive macrocephaly (HP:0004481) | 3.11525212 |
| 19 | Hepatic necrosis (HP:0002605) | 3.03471569 |
| 20 | Congenital stationary night blindness (HP:0007642) | 3.01530117 |
| 21 | Methylmalonic acidemia (HP:0002912) | 2.99570709 |
| 22 | Hypoplasia of the pons (HP:0012110) | 2.93670338 |
| 23 | Opisthotonus (HP:0002179) | 2.93585266 |
| 24 | Visual hallucinations (HP:0002367) | 2.93308355 |
| 25 | Increased hepatocellular lipid droplets (HP:0006565) | 2.91767483 |
| 26 | Lipid accumulation in hepatocytes (HP:0006561) | 2.87364342 |
| 27 | Abnormality of T cells (HP:0002843) | 2.87051072 |
| 28 | Abnormality of placental membranes (HP:0011409) | 2.84256700 |
| 29 | Amniotic constriction ring (HP:0009775) | 2.84256700 |
| 30 | Increased serum lactate (HP:0002151) | 2.83038785 |
| 31 | Cerebral edema (HP:0002181) | 2.66429461 |
| 32 | Duplicated collecting system (HP:0000081) | 2.56743033 |
| 33 | Methylmalonic aciduria (HP:0012120) | 2.55773906 |
| 34 | Cerebral hypomyelination (HP:0006808) | 2.55645755 |
| 35 | Exertional dyspnea (HP:0002875) | 2.53893307 |
| 36 | Abnormality of the labia minora (HP:0012880) | 2.53300253 |
| 37 | Pancreatic cysts (HP:0001737) | 2.52202556 |
| 38 | Abnormality of the prostate (HP:0008775) | 2.51474287 |
| 39 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.46163226 |
| 40 | Increased cerebral lipofuscin (HP:0011813) | 2.41470542 |
| 41 | Scotoma (HP:0000575) | 2.40377756 |
| 42 | Abnormality of the renal collecting system (HP:0004742) | 2.31656487 |
| 43 | Lactic acidosis (HP:0003128) | 2.31207449 |
| 44 | Microvesicular hepatic steatosis (HP:0001414) | 2.24170740 |
| 45 | Lethargy (HP:0001254) | 2.24037270 |
| 46 | Optic disc pallor (HP:0000543) | 2.23229408 |
| 47 | Abnormality of purine metabolism (HP:0004352) | 2.22676913 |
| 48 | Abnormal protein glycosylation (HP:0012346) | 2.22252026 |
| 49 | Abnormal glycosylation (HP:0012345) | 2.22252026 |
| 50 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.22252026 |
| 51 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.22252026 |
| 52 | IgG deficiency (HP:0004315) | 2.18633371 |
| 53 | Oral leukoplakia (HP:0002745) | 2.18176115 |
| 54 | Meckel diverticulum (HP:0002245) | 2.15380493 |
| 55 | Pancreatic fibrosis (HP:0100732) | 2.14795878 |
| 56 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.12733941 |
| 57 | Renal Fanconi syndrome (HP:0001994) | 2.12519431 |
| 58 | Attenuation of retinal blood vessels (HP:0007843) | 2.11681038 |
| 59 | True hermaphroditism (HP:0010459) | 2.10617750 |
| 60 | Megaloblastic anemia (HP:0001889) | 2.09376922 |
| 61 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.08663111 |
| 62 | Type I transferrin isoform profile (HP:0003642) | 2.07953646 |
| 63 | Type 2 muscle fiber atrophy (HP:0003554) | 2.06580596 |
| 64 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.06299489 |
| 65 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.05360170 |
| 66 | Abnormality of the ileum (HP:0001549) | 2.04599026 |
| 67 | Respiratory failure (HP:0002878) | 2.03295636 |
| 68 | Hypomagnesemia (HP:0002917) | 2.03026717 |
| 69 | Parakeratosis (HP:0001036) | 2.01747233 |
| 70 | CNS demyelination (HP:0007305) | 2.01566258 |
| 71 | Abnormality of vitamin B metabolism (HP:0004340) | 2.00340275 |
| 72 | Increased IgM level (HP:0003496) | 1.99884502 |
| 73 | Abnormality of the preputium (HP:0100587) | 1.98287214 |
| 74 | Tetraparesis (HP:0002273) | 1.97453092 |
| 75 | Clubbing of toes (HP:0100760) | 1.95899554 |
| 76 | Spastic diplegia (HP:0001264) | 1.93567196 |
| 77 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.92309656 |
| 78 | Abnormality of alanine metabolism (HP:0010916) | 1.91803958 |
| 79 | Hyperalaninemia (HP:0003348) | 1.91803958 |
| 80 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.91803958 |
| 81 | Abolished electroretinogram (ERG) (HP:0000550) | 1.91441951 |
| 82 | Hypoproteinemia (HP:0003075) | 1.89186327 |
| 83 | Gout (HP:0001997) | 1.88417005 |
| 84 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.88172973 |
| 85 | Exercise intolerance (HP:0003546) | 1.87801312 |
| 86 | Nephronophthisis (HP:0000090) | 1.87066352 |
| 87 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.86584139 |
| 88 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.85465337 |
| 89 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.85465337 |
| 90 | Increased serum pyruvate (HP:0003542) | 1.84019889 |
| 91 | Abnormality of midbrain morphology (HP:0002418) | 1.80553043 |
| 92 | Molar tooth sign on MRI (HP:0002419) | 1.80553043 |
| 93 | Abnormal biliary tract physiology (HP:0012439) | 1.79384883 |
| 94 | Bile duct proliferation (HP:0001408) | 1.79384883 |
| 95 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.78878474 |
| 96 | CNS hypomyelination (HP:0003429) | 1.76936176 |
| 97 | Renal cortical cysts (HP:0000803) | 1.76085446 |
| 98 | Pancytopenia (HP:0001876) | 1.75531036 |
| 99 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.75494684 |
| 100 | Constricted visual fields (HP:0001133) | 1.74801545 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.74230734 |
| 2 | NEK1 | 4.37989504 |
| 3 | TAF1 | 3.88845428 |
| 4 | NUAK1 | 3.71896903 |
| 5 | TSSK6 | 3.36899845 |
| 6 | EIF2AK3 | 2.86942108 |
| 7 | EIF2AK1 | 2.64210317 |
| 8 | TXK | 2.51041692 |
| 9 | MST4 | 2.48840919 |
| 10 | ZAK | 2.44700837 |
| 11 | VRK1 | 2.31004055 |
| 12 | MKNK1 | 2.19127293 |
| 13 | NME2 | 2.05966147 |
| 14 | MAP4K1 | 2.03453544 |
| 15 | MAPKAPK5 | 1.99404463 |
| 16 | ADRBK2 | 1.97590325 |
| 17 | TAOK3 | 1.88195318 |
| 18 | BUB1 | 1.87874819 |
| 19 | TRIM28 | 1.83293182 |
| 20 | PLK3 | 1.77059911 |
| 21 | BCKDK | 1.72101127 |
| 22 | SMG1 | 1.55089701 |
| 23 | GRK1 | 1.53349112 |
| 24 | PLK4 | 1.29434439 |
| 25 | PNCK | 1.26778432 |
| 26 | WNK3 | 1.23720460 |
| 27 | EIF2AK2 | 1.20916391 |
| 28 | DAPK1 | 1.20628833 |
| 29 | INSRR | 1.19099924 |
| 30 | TLK1 | 1.16260260 |
| 31 | WNK4 | 1.11270639 |
| 32 | FRK | 1.10570582 |
| 33 | DYRK2 | 1.09441368 |
| 34 | IKBKB | 0.96574748 |
| 35 | NME1 | 0.95611108 |
| 36 | TEC | 0.95284726 |
| 37 | DAPK2 | 0.94706552 |
| 38 | TIE1 | 0.92860218 |
| 39 | CDC7 | 0.91315137 |
| 40 | OXSR1 | 0.89304946 |
| 41 | PBK | 0.88371673 |
| 42 | PASK | 0.84616055 |
| 43 | FES | 0.84205885 |
| 44 | STK39 | 0.84108098 |
| 45 | GRK5 | 0.79380965 |
| 46 | TNK2 | 0.77245807 |
| 47 | STK16 | 0.70570747 |
| 48 | NEK9 | 0.67908580 |
| 49 | ACVR1B | 0.67749053 |
| 50 | CHEK2 | 0.67284588 |
| 51 | ATR | 0.66942813 |
| 52 | CSNK1A1L | 0.66393821 |
| 53 | PRKCQ | 0.65086723 |
| 54 | ALK | 0.64971151 |
| 55 | WEE1 | 0.64853680 |
| 56 | RPS6KA5 | 0.64809513 |
| 57 | PLK1 | 0.64358012 |
| 58 | CSNK1G3 | 0.63834212 |
| 59 | MAP4K2 | 0.63585125 |
| 60 | CAMK2D | 0.62646493 |
| 61 | SRPK1 | 0.60047080 |
| 62 | IKBKE | 0.58868565 |
| 63 | BMPR1B | 0.58451259 |
| 64 | BMPR2 | 0.57096029 |
| 65 | PAK4 | 0.57075640 |
| 66 | CSNK2A2 | 0.54494788 |
| 67 | CSNK2A1 | 0.53065014 |
| 68 | CSNK1G1 | 0.51938588 |
| 69 | KDR | 0.50572915 |
| 70 | PINK1 | 0.50515704 |
| 71 | TGFBR1 | 0.50440808 |
| 72 | AURKB | 0.50270319 |
| 73 | TTK | 0.47446203 |
| 74 | CSNK1A1 | 0.45552147 |
| 75 | PHKG1 | 0.44303942 |
| 76 | PHKG2 | 0.44303942 |
| 77 | STK4 | 0.44198312 |
| 78 | MAP3K12 | 0.43402731 |
| 79 | TBK1 | 0.42083302 |
| 80 | FGFR1 | 0.41861024 |
| 81 | CSNK1G2 | 0.41748186 |
| 82 | MAP2K6 | 0.40884666 |
| 83 | ITK | 0.40267332 |
| 84 | ATM | 0.39180965 |
| 85 | ADRBK1 | 0.38460831 |
| 86 | CHEK1 | 0.37942646 |
| 87 | RPS6KB1 | 0.37557031 |
| 88 | SYK | 0.37358084 |
| 89 | MAP3K13 | 0.36496128 |
| 90 | MAP3K14 | 0.35916786 |
| 91 | MKNK2 | 0.35629438 |
| 92 | BTK | 0.35005022 |
| 93 | CAMK2A | 0.33197452 |
| 94 | PLK2 | 0.32418337 |
| 95 | LYN | 0.30904975 |
| 96 | PRKCI | 0.30815918 |
| 97 | GSK3A | 0.29014519 |
| 98 | DAPK3 | 0.28509972 |
| 99 | PAK3 | 0.27597877 |
| 100 | CDK7 | 0.25988083 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.31577207 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.08428358 |
| 3 | Protein export_Homo sapiens_hsa03060 | 2.78714965 |
| 4 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.65225985 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.30608403 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 2.22943531 |
| 7 | Ribosome_Homo sapiens_hsa03010 | 2.22526735 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.18946793 |
| 9 | Basal transcription factors_Homo sapiens_hsa03022 | 2.14019753 |
| 10 | Mismatch repair_Homo sapiens_hsa03430 | 2.12258007 |
| 11 | RNA degradation_Homo sapiens_hsa03018 | 2.09962355 |
| 12 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.99413346 |
| 13 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.90026382 |
| 14 | RNA transport_Homo sapiens_hsa03013 | 1.88903228 |
| 15 | Parkinsons disease_Homo sapiens_hsa05012 | 1.88868507 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.87132276 |
| 17 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.83246253 |
| 18 | DNA replication_Homo sapiens_hsa03030 | 1.82298555 |
| 19 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.81214805 |
| 20 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.75882517 |
| 21 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.73270608 |
| 22 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.71837439 |
| 23 | Asthma_Homo sapiens_hsa05310 | 1.69394596 |
| 24 | Allograft rejection_Homo sapiens_hsa05330 | 1.65648291 |
| 25 | Spliceosome_Homo sapiens_hsa03040 | 1.64551842 |
| 26 | Phototransduction_Homo sapiens_hsa04744 | 1.59562390 |
| 27 | Base excision repair_Homo sapiens_hsa03410 | 1.57986478 |
| 28 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.54881511 |
| 29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.52388487 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.50202290 |
| 31 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.47651838 |
| 32 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.41481310 |
| 33 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.38643777 |
| 34 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.33715217 |
| 35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.31518800 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.30411649 |
| 37 | Huntingtons disease_Homo sapiens_hsa05016 | 1.30097876 |
| 38 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.29215269 |
| 39 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.25758079 |
| 40 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.24521718 |
| 41 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.23009406 |
| 42 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.21700411 |
| 43 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.13653840 |
| 44 | Alzheimers disease_Homo sapiens_hsa05010 | 1.09557344 |
| 45 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.08781992 |
| 46 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.07860731 |
| 47 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.06927064 |
| 48 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.02121347 |
| 49 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.01664218 |
| 50 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.95004357 |
| 51 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.87259330 |
| 52 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.85609217 |
| 53 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.83397136 |
| 54 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.83317895 |
| 55 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.79727049 |
| 56 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.78534640 |
| 57 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.76623044 |
| 58 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.75054382 |
| 59 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.71323356 |
| 60 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.70615315 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.70252066 |
| 62 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.67849264 |
| 63 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.67799215 |
| 64 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.64432199 |
| 65 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.64411651 |
| 66 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.64164241 |
| 67 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.62463601 |
| 68 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.62027068 |
| 69 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.60655153 |
| 70 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.59869113 |
| 71 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.59683744 |
| 72 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.59334654 |
| 73 | Peroxisome_Homo sapiens_hsa04146 | 0.59115097 |
| 74 | Retinol metabolism_Homo sapiens_hsa00830 | 0.58606873 |
| 75 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.57939118 |
| 76 | Carbon metabolism_Homo sapiens_hsa01200 | 0.56392794 |
| 77 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.55470702 |
| 78 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.55206349 |
| 79 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.52929969 |
| 80 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.51274186 |
| 81 | Mineral absorption_Homo sapiens_hsa04978 | 0.51198913 |
| 82 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.51138964 |
| 83 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.50604184 |
| 84 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.50459320 |
| 85 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.47991755 |
| 86 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47559618 |
| 87 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.47272401 |
| 88 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.46956215 |
| 89 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.46090903 |
| 90 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.43759605 |
| 91 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.42205018 |
| 92 | Measles_Homo sapiens_hsa05162 | 0.41473858 |
| 93 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.41289883 |
| 94 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.40794628 |
| 95 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.39110219 |
| 96 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.38469052 |
| 97 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.35692955 |
| 98 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.35325572 |
| 99 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.33743905 |
| 100 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.33673339 |

