Rank | Gene Set | Z-score |
---|---|---|
1 | proline biosynthetic process (GO:0006561) | 6.83881791 |
2 | mitotic chromosome condensation (GO:0007076) | 5.51570107 |
3 | transcription from mitochondrial promoter (GO:0006390) | 5.50402017 |
4 | embryonic process involved in female pregnancy (GO:0060136) | 5.47050368 |
5 | replication fork processing (GO:0031297) | 5.42967854 |
6 | DNA deamination (GO:0045006) | 4.94364871 |
7 | ribosomal small subunit biogenesis (GO:0042274) | 4.91178648 |
8 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 4.91133679 |
9 | proline metabolic process (GO:0006560) | 4.82672917 |
10 | establishment of apical/basal cell polarity (GO:0035089) | 4.80037386 |
11 | establishment of integrated proviral latency (GO:0075713) | 4.77968029 |
12 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 4.71261297 |
13 | nuclear pore complex assembly (GO:0051292) | 4.69998122 |
14 | formation of translation preinitiation complex (GO:0001731) | 4.60779940 |
15 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 4.54356544 |
16 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 4.54356544 |
17 | regulation of translational fidelity (GO:0006450) | 4.50434953 |
18 | mitotic G1 DNA damage checkpoint (GO:0031571) | 4.39624978 |
19 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.33187817 |
20 | dosage compensation (GO:0007549) | 4.22589147 |
21 | regulation of integrin activation (GO:0033623) | 4.22148864 |
22 | positive regulation of protein homooligomerization (GO:0032464) | 4.17782342 |
23 | negative regulation of mRNA processing (GO:0050686) | 4.17205707 |
24 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.16376530 |
25 | mitochondrial DNA metabolic process (GO:0032042) | 4.15519278 |
26 | maturation of SSU-rRNA (GO:0030490) | 4.10915431 |
27 | establishment of monopolar cell polarity (GO:0061162) | 4.07772846 |
28 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 4.07772846 |
29 | regulation of RNA export from nucleus (GO:0046831) | 4.07181384 |
30 | DNA strand renaturation (GO:0000733) | 4.06510967 |
31 | protein localization to chromosome, centromeric region (GO:0071459) | 4.06293056 |
32 | negative regulation of RNA splicing (GO:0033119) | 4.04246896 |
33 | viral mRNA export from host cell nucleus (GO:0046784) | 4.02623633 |
34 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 4.01914449 |
35 | protein complex localization (GO:0031503) | 4.01907061 |
36 | regulation of sister chromatid cohesion (GO:0007063) | 4.01725917 |
37 | mitotic metaphase plate congression (GO:0007080) | 4.00558734 |
38 | G1 DNA damage checkpoint (GO:0044783) | 3.94480807 |
39 | DNA topological change (GO:0006265) | 3.91506752 |
40 | DNA strand elongation (GO:0022616) | 3.91474866 |
41 | base-excision repair (GO:0006284) | 3.85451278 |
42 | mitotic G1/S transition checkpoint (GO:0044819) | 3.83852690 |
43 | DNA unwinding involved in DNA replication (GO:0006268) | 3.82988436 |
44 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.81608880 |
45 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.81340956 |
46 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.81340956 |
47 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.81340956 |
48 | oxidative demethylation (GO:0070989) | 3.76546744 |
49 | mRNA cleavage (GO:0006379) | 3.73445398 |
50 | establishment of viral latency (GO:0019043) | 3.68365534 |
51 | regulation of translational termination (GO:0006449) | 3.67350066 |
52 | termination of RNA polymerase II transcription (GO:0006369) | 3.64959249 |
53 | telomere maintenance via recombination (GO:0000722) | 3.63800706 |
54 | meiotic chromosome segregation (GO:0045132) | 3.60015334 |
55 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.58646113 |
56 | positive regulation of chromosome segregation (GO:0051984) | 3.56085416 |
57 | negative regulation of mRNA metabolic process (GO:1903312) | 3.55489402 |
58 | viral transcription (GO:0019083) | 3.52888691 |
59 | chromosome condensation (GO:0030261) | 3.52283802 |
60 | regulation of protein homooligomerization (GO:0032462) | 3.51694821 |
61 | mitotic sister chromatid cohesion (GO:0007064) | 3.49812686 |
62 | mitotic sister chromatid segregation (GO:0000070) | 3.49127248 |
63 | cellular protein complex localization (GO:0034629) | 3.45687689 |
64 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.43559339 |
65 | regulation of gene silencing by miRNA (GO:0060964) | 3.43559339 |
66 | regulation of gene silencing by RNA (GO:0060966) | 3.43559339 |
67 | mitotic recombination (GO:0006312) | 3.41544687 |
68 | translational termination (GO:0006415) | 3.41445167 |
69 | poly(A)+ mRNA export from nucleus (GO:0016973) | 3.41404841 |
70 | negative regulation of cell cycle arrest (GO:0071157) | 3.41114391 |
71 | pore complex assembly (GO:0046931) | 3.41084355 |
72 | pre-miRNA processing (GO:0031054) | 3.39839687 |
73 | ribosome biogenesis (GO:0042254) | 3.38404826 |
74 | mitotic nuclear envelope disassembly (GO:0007077) | 3.37286432 |
75 | kinetochore organization (GO:0051383) | 3.34191988 |
76 | kinetochore assembly (GO:0051382) | 3.33329268 |
77 | RNA stabilization (GO:0043489) | 3.33092294 |
78 | mRNA stabilization (GO:0048255) | 3.33092294 |
79 | DNA replication checkpoint (GO:0000076) | 3.30975818 |
80 | sister chromatid segregation (GO:0000819) | 3.30612726 |
81 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.30264289 |
82 | regulation of DNA damage checkpoint (GO:2000001) | 3.30184736 |
83 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.30058662 |
84 | protein-DNA complex disassembly (GO:0032986) | 3.29418904 |
85 | nucleosome disassembly (GO:0006337) | 3.29418904 |
86 | ribosome assembly (GO:0042255) | 3.29349496 |
87 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.29109571 |
88 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.27389077 |
89 | trophectodermal cell differentiation (GO:0001829) | 3.26061544 |
90 | non-recombinational repair (GO:0000726) | 3.23990357 |
91 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.23990357 |
92 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.23880454 |
93 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.23052821 |
94 | negative regulation of JAK-STAT cascade (GO:0046426) | 3.22365697 |
95 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.21024927 |
96 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.20935551 |
97 | protein localization to kinetochore (GO:0034501) | 3.20217716 |
98 | regulation of double-strand break repair (GO:2000779) | 3.19643647 |
99 | embryonic placenta development (GO:0001892) | 3.18645487 |
100 | telomere maintenance via telomere lengthening (GO:0010833) | 3.18154281 |
101 | ribosomal large subunit biogenesis (GO:0042273) | 3.17029120 |
102 | DNA double-strand break processing (GO:0000729) | 3.16390891 |
103 | chromatin assembly (GO:0031497) | 3.16033879 |
104 | histone arginine methylation (GO:0034969) | 3.14352675 |
105 | nuclear envelope disassembly (GO:0051081) | 3.13699459 |
106 | membrane disassembly (GO:0030397) | 3.13699459 |
107 | ribosomal small subunit assembly (GO:0000028) | 3.12081237 |
108 | metaphase plate congression (GO:0051310) | 3.11784255 |
109 | DNA conformation change (GO:0071103) | 3.09447197 |
110 | histone H4-K12 acetylation (GO:0043983) | 3.07878302 |
111 | heterochromatin organization (GO:0070828) | 3.07702026 |
112 | DNA duplex unwinding (GO:0032508) | 3.07453001 |
113 | positive regulation by host of viral transcription (GO:0043923) | 3.06798926 |
114 | DNA replication initiation (GO:0006270) | 3.05676135 |
115 | DNA geometric change (GO:0032392) | 3.05486238 |
116 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.04703724 |
117 | apoptotic process involved in morphogenesis (GO:0060561) | 3.03332957 |
118 | L-serine metabolic process (GO:0006563) | 3.03241900 |
119 | mRNA export from nucleus (GO:0006406) | 3.02215315 |
120 | translational initiation (GO:0006413) | 3.00098326 |
121 | translational elongation (GO:0006414) | 2.99901213 |
122 | DNA packaging (GO:0006323) | 2.98339696 |
123 | chromatin assembly or disassembly (GO:0006333) | 2.98215250 |
124 | mitochondrial RNA metabolic process (GO:0000959) | 2.96652163 |
125 | mRNA transport (GO:0051028) | 2.96247153 |
126 | IMP biosynthetic process (GO:0006188) | 2.95034633 |
127 | DNA ligation (GO:0006266) | 2.94364499 |
128 | DNA integration (GO:0015074) | 2.94262601 |
129 | RNA export from nucleus (GO:0006405) | 2.93037158 |
130 | nuclear pore organization (GO:0006999) | 2.89383502 |
131 | resolution of meiotic recombination intermediates (GO:0000712) | 2.89133855 |
132 | establishment of chromosome localization (GO:0051303) | 2.86879657 |
133 | rRNA transcription (GO:0009303) | 2.86871178 |
134 | maturation of 5.8S rRNA (GO:0000460) | 2.86601168 |
135 | embryonic camera-type eye development (GO:0031076) | 2.85112735 |
136 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.84942852 |
137 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.84423691 |
138 | ATP-dependent chromatin remodeling (GO:0043044) | 2.82444360 |
139 | nuclear envelope organization (GO:0006998) | 2.81415734 |
140 | viral life cycle (GO:0019058) | 2.81068705 |
141 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.79685695 |
142 | mRNA splicing, via spliceosome (GO:0000398) | 2.78407469 |
143 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.78407469 |
144 | protein targeting to ER (GO:0045047) | 2.78131918 |
145 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.77665246 |
146 | nucleobase biosynthetic process (GO:0046112) | 2.77586343 |
147 | cotranslational protein targeting to membrane (GO:0006613) | 2.77241754 |
148 | nodal signaling pathway (GO:0038092) | 2.76933683 |
149 | RNA splicing, via transesterification reactions (GO:0000375) | 2.76558930 |
150 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.76234277 |
151 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.76234277 |
152 | protein complex disassembly (GO:0043241) | 2.75264558 |
153 | IMP metabolic process (GO:0046040) | 2.74773265 |
154 | cellular protein complex disassembly (GO:0043624) | 2.72964665 |
155 | rRNA processing (GO:0006364) | 2.72320087 |
156 | peptidyl-arginine methylation (GO:0018216) | 2.71920742 |
157 | peptidyl-arginine N-methylation (GO:0035246) | 2.71920742 |
158 | regulation of mitotic spindle organization (GO:0060236) | 2.71788832 |
159 | regulation of transcription from RNA polymerase I promoter (GO:0006356) | 2.70418902 |
160 | regulation of mRNA stability (GO:0043488) | 2.67610252 |
161 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.67418118 |
162 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.66668750 |
163 | chromatin remodeling at centromere (GO:0031055) | 2.66299473 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.67592722 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.87274793 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.74111690 |
4 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.19046508 |
5 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.84135250 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.69559118 |
7 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 2.64755752 |
8 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.61967455 |
9 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.45784408 |
10 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.35405419 |
11 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.34126531 |
12 | * MYC_22102868_ChIP-Seq_BL_Human | 2.31095656 |
13 | * VDR_21846776_ChIP-Seq_THP-1_Human | 2.17543269 |
14 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.12888884 |
15 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.12888884 |
16 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.12888884 |
17 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.97097133 |
18 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.87673692 |
19 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.83389047 |
20 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.77889900 |
21 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.75379359 |
22 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.74058757 |
23 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.72349444 |
24 | * XRN2_22483619_ChIP-Seq_HELA_Human | 1.69938499 |
25 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.69798562 |
26 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.69737382 |
27 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.69188937 |
28 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.68085700 |
29 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.67378170 |
30 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.63102903 |
31 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.61346034 |
32 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.60205913 |
33 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.59503708 |
34 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.57542703 |
35 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.57023529 |
36 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.56853642 |
37 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.56607952 |
38 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.54959722 |
39 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.53807969 |
40 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.53508984 |
41 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.52949089 |
42 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.52515393 |
43 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.52199201 |
44 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.50922925 |
45 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.50738594 |
46 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.50265930 |
47 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.49817073 |
48 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.47947150 |
49 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.47429279 |
50 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.46551692 |
51 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 1.45853490 |
52 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.45434516 |
53 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.45154942 |
54 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.44111358 |
55 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.43815723 |
56 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.43409786 |
57 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.39906523 |
58 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.39861222 |
59 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.38092409 |
60 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.35137232 |
61 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.33717814 |
62 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.33025369 |
63 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.32773800 |
64 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.27333332 |
65 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.26360731 |
66 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.25747566 |
67 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.24745416 |
68 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.24170558 |
69 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.24086280 |
70 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.23590105 |
71 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.23054926 |
72 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.22683704 |
73 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.22417458 |
74 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.21815230 |
75 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.20488480 |
76 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.19345610 |
77 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.17288223 |
78 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.16044869 |
79 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.15469204 |
80 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.15306406 |
81 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.14869554 |
82 | * LXR_22292898_ChIP-Seq_THP-1_Human | 1.14647850 |
83 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.13938384 |
84 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.13611295 |
85 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.13047809 |
86 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.12466186 |
87 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.11933034 |
88 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.11875217 |
89 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.08954525 |
90 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.08927537 |
91 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.08875015 |
92 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.08406847 |
93 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.08290559 |
94 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.08070484 |
95 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.07795043 |
96 | POU5F1_18692474_ChIP-Seq_MESCs_Mouse | 1.06916679 |
97 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.05551491 |
98 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.04512649 |
99 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.04224641 |
100 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.04155916 |
101 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.04151970 |
102 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.04091357 |
103 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.03424681 |
104 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.03222641 |
105 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.03157319 |
106 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.02297182 |
107 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.02055246 |
108 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.01602655 |
109 | SOX2_18692474_ChIP-Seq_MESCs_Mouse | 1.01585827 |
110 | * PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.99906095 |
111 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.99334803 |
112 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.98924377 |
113 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.98715913 |
114 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.98654680 |
115 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.98608359 |
116 | ATF3_27146783_Chip-Seq_COLON_Human | 0.98271631 |
117 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.97934487 |
118 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.97753281 |
119 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.97635601 |
120 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.93989546 |
121 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.90999976 |
122 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.89436261 |
123 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.89267073 |
124 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88559094 |
125 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.88320642 |
126 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.88052364 |
127 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.87807272 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 5.20225107 |
2 | MP0010094_abnormal_chromosome_stability | 3.40788174 |
3 | MP0010030_abnormal_orbit_morphology | 3.37632760 |
4 | MP0009278_abnormal_bone_marrow | 3.34120092 |
5 | MP0004957_abnormal_blastocyst_morpholog | 3.12824900 |
6 | MP0003111_abnormal_nucleus_morphology | 2.92964776 |
7 | MP0003693_abnormal_embryo_hatching | 2.86728890 |
8 | MP0010352_gastrointestinal_tract_polyps | 2.64425487 |
9 | MP0003077_abnormal_cell_cycle | 2.49029260 |
10 | MP0005076_abnormal_cell_differentiation | 2.41203633 |
11 | MP0002877_abnormal_melanocyte_morpholog | 2.31847959 |
12 | MP0004233_abnormal_muscle_weight | 2.31373875 |
13 | MP0005171_absent_coat_pigmentation | 2.30778049 |
14 | MP0003890_abnormal_embryonic-extraembry | 2.27722186 |
15 | MP0008058_abnormal_DNA_repair | 2.08498266 |
16 | MP0008932_abnormal_embryonic_tissue | 2.05470019 |
17 | MP0009672_abnormal_birth_weight | 2.02419829 |
18 | MP0002084_abnormal_developmental_patter | 1.97963686 |
19 | MP0001730_embryonic_growth_arrest | 1.95369891 |
20 | MP0004197_abnormal_fetal_growth/weight/ | 1.92176654 |
21 | MP0005397_hematopoietic_system_phenotyp | 1.91010779 |
22 | MP0001545_abnormal_hematopoietic_system | 1.91010779 |
23 | MP0001697_abnormal_embryo_size | 1.90877100 |
24 | MP0002086_abnormal_extraembryonic_tissu | 1.88831802 |
25 | MP0009379_abnormal_foot_pigmentation | 1.88504606 |
26 | MP0000350_abnormal_cell_proliferation | 1.88049483 |
27 | MP0002009_preneoplasia | 1.87275513 |
28 | MP0003119_abnormal_digestive_system | 1.86043324 |
29 | MP0010234_abnormal_vibrissa_follicle | 1.85641194 |
30 | MP0002085_abnormal_embryonic_tissue | 1.83226907 |
31 | MP0003567_abnormal_fetal_cardiomyocyte | 1.82054085 |
32 | MP0001293_anophthalmia | 1.77060433 |
33 | MP0005380_embryogenesis_phenotype | 1.77035777 |
34 | MP0001672_abnormal_embryogenesis/_devel | 1.77035777 |
35 | MP0003786_premature_aging | 1.76312019 |
36 | MP0000490_abnormal_crypts_of | 1.75771020 |
37 | MP0003283_abnormal_digestive_organ | 1.72843949 |
38 | MP0003705_abnormal_hypodermis_morpholog | 1.62880505 |
39 | MP0008877_abnormal_DNA_methylation | 1.61251329 |
40 | MP0002653_abnormal_ependyma_morphology | 1.60106169 |
41 | MP0010307_abnormal_tumor_latency | 1.59841792 |
42 | MP0008995_early_reproductive_senescence | 1.57191720 |
43 | MP0009053_abnormal_anal_canal | 1.57138425 |
44 | MP0003984_embryonic_growth_retardation | 1.53261794 |
45 | MP0001346_abnormal_lacrimal_gland | 1.53201518 |
46 | MP0002282_abnormal_trachea_morphology | 1.52550590 |
47 | MP0002088_abnormal_embryonic_growth/wei | 1.49545577 |
48 | MP0002080_prenatal_lethality | 1.46008296 |
49 | MP0005451_abnormal_body_composition | 1.45247160 |
50 | MP0004133_heterotaxia | 1.45245314 |
51 | MP0008007_abnormal_cellular_replicative | 1.37823977 |
52 | MP0002249_abnormal_larynx_morphology | 1.37712538 |
53 | MP0003453_abnormal_keratinocyte_physiol | 1.35341352 |
54 | MP0003315_abnormal_perineum_morphology | 1.33118879 |
55 | MP0002396_abnormal_hematopoietic_system | 1.31778358 |
56 | MP0005174_abnormal_tail_pigmentation | 1.30869490 |
57 | MP0000678_abnormal_parathyroid_gland | 1.24397470 |
58 | MP0000566_synostosis | 1.22425936 |
59 | MP0002019_abnormal_tumor_incidence | 1.22411093 |
60 | MP0002111_abnormal_tail_morphology | 1.21823529 |
61 | MP0005623_abnormal_meninges_morphology | 1.19115209 |
62 | MP0000537_abnormal_urethra_morphology | 1.18718090 |
63 | MP0005257_abnormal_intraocular_pressure | 1.13082865 |
64 | MP0000313_abnormal_cell_death | 1.07999145 |
65 | MP0003123_paternal_imprinting | 1.05019244 |
66 | MP0004858_abnormal_nervous_system | 1.04449788 |
67 | MP0002932_abnormal_joint_morphology | 1.03888839 |
68 | MP0003935_abnormal_craniofacial_develop | 1.02833426 |
69 | MP0000371_diluted_coat_color | 1.02708691 |
70 | MP0006072_abnormal_retinal_apoptosis | 1.02075314 |
71 | MP0002089_abnormal_postnatal_growth/wei | 1.01449056 |
72 | MP0001881_abnormal_mammary_gland | 1.00123905 |
73 | MP0003937_abnormal_limbs/digits/tail_de | 0.99371209 |
74 | MP0003566_abnormal_cell_adhesion | 0.98013038 |
75 | MP0003718_maternal_effect | 0.96967467 |
76 | MP0001727_abnormal_embryo_implantation | 0.96486765 |
77 | MP0004264_abnormal_extraembryonic_tissu | 0.94864519 |
78 | MP0003755_abnormal_palate_morphology | 0.93579116 |
79 | MP0005621_abnormal_cell_physiology | 0.91573766 |
80 | MP0000432_abnormal_head_morphology | 0.90391025 |
81 | MP0002697_abnormal_eye_size | 0.90173430 |
82 | MP0002092_abnormal_eye_morphology | 0.87873161 |
83 | MP0003942_abnormal_urinary_system | 0.87103062 |
84 | MP0002098_abnormal_vibrissa_morphology | 0.86951440 |
85 | MP0001216_abnormal_epidermal_layer | 0.86942671 |
86 | MP0002254_reproductive_system_inflammat | 0.86293670 |
87 | MP0009333_abnormal_splenocyte_physiolog | 0.86180206 |
88 | MP0000470_abnormal_stomach_morphology | 0.86107348 |
89 | MP0000462_abnormal_digestive_system | 0.85820613 |
90 | MP0000579_abnormal_nail_morphology | 0.85482276 |
91 | MP0005501_abnormal_skin_physiology | 0.85245201 |
92 | MP0000627_abnormal_mammary_gland | 0.84951936 |
93 | MP0006292_abnormal_olfactory_placode | 0.84888934 |
94 | MP0005666_abnormal_adipose_tissue | 0.84774004 |
95 | MP0001286_abnormal_eye_development | 0.84549097 |
96 | MP0001340_abnormal_eyelid_morphology | 0.84291882 |
97 | MP0002114_abnormal_axial_skeleton | 0.83265308 |
98 | MP0005023_abnormal_wound_healing | 0.80850129 |
99 | MP0001348_abnormal_lacrimal_gland | 0.80689686 |
100 | MP0001849_ear_inflammation | 0.80335491 |
101 | MP0000477_abnormal_intestine_morphology | 0.80241438 |
102 | MP0003806_abnormal_nucleotide_metabolis | 0.80069923 |
103 | MP0005384_cellular_phenotype | 0.79847697 |
104 | MP0002796_impaired_skin_barrier | 0.79639030 |
105 | MP0002116_abnormal_craniofacial_bone | 0.79076797 |
106 | MP0002075_abnormal_coat/hair_pigmentati | 0.78007609 |
107 | MP0003828_pulmonary_edema | 0.77950341 |
108 | MP0003385_abnormal_body_wall | 0.76882458 |
109 | MP0001145_abnormal_male_reproductive | 0.76752481 |
110 | MP0004808_abnormal_hematopoietic_stem | 0.76004648 |
111 | MP0001915_intracranial_hemorrhage | 0.75946851 |
112 | MP0000762_abnormal_tongue_morphology | 0.75373258 |
113 | MP0009703_decreased_birth_body | 0.74032597 |
114 | MP0000358_abnormal_cell_content/ | 0.73807139 |
115 | MP0002925_abnormal_cardiovascular_devel | 0.73658617 |
116 | MP0000703_abnormal_thymus_morphology | 0.72912072 |
117 | MP0002269_muscular_atrophy | 0.72750900 |
118 | MP0009697_abnormal_copulation | 0.72673105 |
119 | MP0003115_abnormal_respiratory_system | 0.72614060 |
120 | MP0000377_abnormal_hair_follicle | 0.72315456 |
121 | MP0000516_abnormal_urinary_system | 0.71499945 |
122 | MP0005367_renal/urinary_system_phenotyp | 0.71499945 |
123 | MP0004782_abnormal_surfactant_physiolog | 0.71391111 |
124 | MP0010630_abnormal_cardiac_muscle | 0.69441003 |
125 | MP0003941_abnormal_skin_development | 0.69354294 |
126 | MP0000467_abnormal_esophagus_morphology | 0.69291370 |
127 | MP0000733_abnormal_muscle_development | 0.69246208 |
128 | MP0000049_abnormal_middle_ear | 0.67936837 |
129 | MP0002060_abnormal_skin_morphology | 0.67388923 |
130 | MP0000428_abnormal_craniofacial_morphol | 0.66254780 |
131 | MP0001784_abnormal_fluid_regulation | 0.66023249 |
132 | MP0002210_abnormal_sex_determination | 0.65809409 |
133 | MP0003861_abnormal_nervous_system | 0.65778684 |
134 | MP0004185_abnormal_adipocyte_glucose | 0.64952791 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Facial hemangioma (HP:0000329) | 4.74836395 |
2 | Rib fusion (HP:0000902) | 4.67362757 |
3 | Poikiloderma (HP:0001029) | 3.89281401 |
4 | Annular pancreas (HP:0001734) | 3.85713156 |
5 | Concave nail (HP:0001598) | 3.85041804 |
6 | Ulnar bowing (HP:0003031) | 3.77129066 |
7 | Rectal fistula (HP:0100590) | 3.66841910 |
8 | Rectovaginal fistula (HP:0000143) | 3.66841910 |
9 | Pustule (HP:0200039) | 3.64346483 |
10 | Hyperacusis (HP:0010780) | 3.53282519 |
11 | Selective tooth agenesis (HP:0001592) | 3.48456999 |
12 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.44735640 |
13 | Chromsome breakage (HP:0040012) | 3.39879671 |
14 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 3.36104486 |
15 | Short humerus (HP:0005792) | 3.34181953 |
16 | Intestinal fistula (HP:0100819) | 3.32683469 |
17 | Aplasia/hypoplasia of the humerus (HP:0006507) | 3.32398284 |
18 | Progressive muscle weakness (HP:0003323) | 3.30186305 |
19 | Basal cell carcinoma (HP:0002671) | 3.26001386 |
20 | Volvulus (HP:0002580) | 3.23055400 |
21 | Absent radius (HP:0003974) | 3.22673695 |
22 | Vaginal fistula (HP:0004320) | 3.20514264 |
23 | Turricephaly (HP:0000262) | 3.14898853 |
24 | Patellar aplasia (HP:0006443) | 3.14573282 |
25 | Multiple enchondromatosis (HP:0005701) | 3.07838641 |
26 | Alopecia of scalp (HP:0002293) | 3.06560125 |
27 | Squamous cell carcinoma (HP:0002860) | 3.04253922 |
28 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.02395987 |
29 | Absent forearm bone (HP:0003953) | 3.02310406 |
30 | Aplasia involving forearm bones (HP:0009822) | 3.02310406 |
31 | Coronal craniosynostosis (HP:0004440) | 2.98407526 |
32 | Absent thumb (HP:0009777) | 2.97168655 |
33 | Tongue fasciculations (HP:0001308) | 2.96337483 |
34 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.93123661 |
35 | Orthostatic hypotension (HP:0001278) | 2.92121242 |
36 | Vertebral hypoplasia (HP:0008417) | 2.89847218 |
37 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 2.89847218 |
38 | Hypochromic microcytic anemia (HP:0004840) | 2.87369815 |
39 | Abnormal number of erythroid precursors (HP:0012131) | 2.85892064 |
40 | Increased nuchal translucency (HP:0010880) | 2.83172557 |
41 | Abnormal hemoglobin (HP:0011902) | 2.80497497 |
42 | Broad alveolar ridges (HP:0000187) | 2.78075427 |
43 | Insomnia (HP:0100785) | 2.77313208 |
44 | Intestinal atresia (HP:0011100) | 2.75690900 |
45 | Muscle fibrillation (HP:0010546) | 2.75632242 |
46 | Abnormality of the astrocytes (HP:0100707) | 2.74374586 |
47 | Astrocytoma (HP:0009592) | 2.74374586 |
48 | Ependymoma (HP:0002888) | 2.65821297 |
49 | Increased IgM level (HP:0003496) | 2.64607677 |
50 | Abnormal number of incisors (HP:0011064) | 2.63950573 |
51 | Microvesicular hepatic steatosis (HP:0001414) | 2.63864934 |
52 | Birth length less than 3rd percentile (HP:0003561) | 2.63775846 |
53 | Male infertility (HP:0003251) | 2.59909342 |
54 | Abnormality of the labia minora (HP:0012880) | 2.58117212 |
55 | Trismus (HP:0000211) | 2.56758875 |
56 | Overriding aorta (HP:0002623) | 2.54153529 |
57 | Congenital hip dislocation (HP:0001374) | 2.52170999 |
58 | Abnormality of the aortic arch (HP:0012303) | 2.48375984 |
59 | Progressive external ophthalmoplegia (HP:0000590) | 2.44852986 |
60 | Short chin (HP:0000331) | 2.44793529 |
61 | Premature graying of hair (HP:0002216) | 2.41825845 |
62 | Anteriorly placed anus (HP:0001545) | 2.39495794 |
63 | Cerebral aneurysm (HP:0004944) | 2.39241252 |
64 | High anterior hairline (HP:0009890) | 2.34817806 |
65 | Neoplasm of the oral cavity (HP:0100649) | 2.32963767 |
66 | Achilles tendon contracture (HP:0001771) | 2.30741195 |
67 | Vertebral fusion (HP:0002948) | 2.28128737 |
68 | Spastic diplegia (HP:0001264) | 2.26150411 |
69 | Broad distal phalanx of finger (HP:0009836) | 2.24007050 |
70 | Septate vagina (HP:0001153) | 2.23100869 |
71 | Elfin facies (HP:0004428) | 2.21158003 |
72 | Macrocytic anemia (HP:0001972) | 2.20942887 |
73 | Abnormality of male internal genitalia (HP:0000022) | 2.20463262 |
74 | Acute lymphatic leukemia (HP:0006721) | 2.18949161 |
75 | Pseudobulbar signs (HP:0002200) | 2.18745844 |
76 | Atresia of the external auditory canal (HP:0000413) | 2.17305166 |
77 | Short 5th finger (HP:0009237) | 2.16350274 |
78 | Bowing of the arm (HP:0006488) | 2.16306539 |
79 | Bowed forearm bones (HP:0003956) | 2.16306539 |
80 | Abnormality of the umbilical cord (HP:0010881) | 2.13804001 |
81 | Increased number of teeth (HP:0011069) | 2.13671545 |
82 | Rhabdomyosarcoma (HP:0002859) | 2.13538035 |
83 | Cortical dysplasia (HP:0002539) | 2.12788628 |
84 | Hypotelorism (HP:0000601) | 2.12106569 |
85 | Glioma (HP:0009733) | 2.11602101 |
86 | Long palpebral fissure (HP:0000637) | 2.10831108 |
87 | Renal duplication (HP:0000075) | 2.10091361 |
88 | Capillary hemangiomas (HP:0005306) | 2.10073299 |
89 | Duplication of thumb phalanx (HP:0009942) | 2.09824324 |
90 | Ragged-red muscle fibers (HP:0003200) | 2.08813396 |
91 | Hamartoma (HP:0010566) | 2.08666905 |
92 | Hypochromic anemia (HP:0001931) | 2.07798142 |
93 | Asymmetry of the thorax (HP:0001555) | 2.05774224 |
94 | Choanal stenosis (HP:0000452) | 2.05651134 |
95 | Medulloblastoma (HP:0002885) | 2.05163034 |
96 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.04754320 |
97 | Premature skin wrinkling (HP:0100678) | 2.04736851 |
98 | Abnormality of reticulocytes (HP:0004312) | 2.04407880 |
99 | Colon cancer (HP:0003003) | 2.03795177 |
100 | Alacrima (HP:0000522) | 2.03738424 |
101 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.03613393 |
102 | Gastrointestinal atresia (HP:0002589) | 2.01341902 |
103 | Short thumb (HP:0009778) | 1.99323662 |
104 | Breast hypoplasia (HP:0003187) | 1.97762693 |
105 | Abnormality of the ileum (HP:0001549) | 1.97051289 |
106 | Broad thumb (HP:0011304) | 1.96608612 |
107 | Overlapping toe (HP:0001845) | 1.96300389 |
108 | Pallor (HP:0000980) | 1.95500343 |
109 | Spinal muscular atrophy (HP:0007269) | 1.93878450 |
110 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.93572346 |
111 | Hypoplasia of the radius (HP:0002984) | 1.93566743 |
112 | Albinism (HP:0001022) | 1.93337934 |
113 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.93141772 |
114 | IgA deficiency (HP:0002720) | 1.93038908 |
115 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.92649963 |
116 | Single umbilical artery (HP:0001195) | 1.92649963 |
117 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.92649963 |
118 | Abnormality of the Achilles tendon (HP:0005109) | 1.92450454 |
119 | Partial duplication of thumb phalanx (HP:0009944) | 1.91020346 |
120 | Dysautonomia (HP:0002459) | 1.90714718 |
121 | Proximal placement of thumb (HP:0009623) | 1.90421314 |
122 | Missing ribs (HP:0000921) | 1.89387430 |
123 | Patellar dislocation (HP:0002999) | 1.88247240 |
124 | Hemivertebrae (HP:0002937) | 1.87845405 |
125 | Split hand (HP:0001171) | 1.87794938 |
126 | Bifid uvula (HP:0000193) | 1.86746230 |
127 | Urethral obstruction (HP:0000796) | 1.86301390 |
128 | Hypotrichosis (HP:0001006) | 1.85356118 |
129 | Deviation of the thumb (HP:0009603) | 1.84004493 |
130 | Abnormality of the preputium (HP:0100587) | 1.83576964 |
131 | Neoplasm of striated muscle (HP:0009728) | 1.82291481 |
132 | Short 4th metacarpal (HP:0010044) | 1.82285810 |
133 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.82285810 |
134 | Glossoptosis (HP:0000162) | 1.82211594 |
135 | Abnormality of the calcaneus (HP:0008364) | 1.81951234 |
136 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.80692929 |
137 | Rough bone trabeculation (HP:0100670) | 1.80616349 |
138 | Partial duplication of the phalanx of hand (HP:0009999) | 1.80405612 |
139 | Deep palmar crease (HP:0006191) | 1.76429143 |
140 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.75966236 |
141 | Abnormality of the salivary glands (HP:0010286) | 1.75150233 |
142 | Insidious onset (HP:0003587) | 1.75046799 |
143 | Termporal pattern (HP:0011008) | 1.75046799 |
144 | Disproportionate tall stature (HP:0001519) | 1.74651437 |
145 | Abnormality of the anterior horn cell (HP:0006802) | 1.74240830 |
146 | Degeneration of anterior horn cells (HP:0002398) | 1.74240830 |
147 | Horseshoe kidney (HP:0000085) | 1.73987099 |
148 | Embryonal renal neoplasm (HP:0011794) | 1.73299437 |
149 | Diaphragmatic weakness (HP:0009113) | 1.71475471 |
150 | Deep philtrum (HP:0002002) | 1.71215316 |
151 | Abnormality of the alveolar ridges (HP:0006477) | 1.71008103 |
152 | Reticulocytopenia (HP:0001896) | 1.70053046 |
153 | Heterotopia (HP:0002282) | 1.69650085 |
154 | Joint stiffness (HP:0001387) | 1.69596436 |
155 | Abnormality of abdominal situs (HP:0011620) | 1.69486862 |
156 | Abdominal situs inversus (HP:0003363) | 1.69486862 |
157 | Abnormality of cochlea (HP:0000375) | 1.66877325 |
158 | Arnold-Chiari malformation (HP:0002308) | 1.65488098 |
159 | Meckel diverticulum (HP:0002245) | 1.65125692 |
160 | 11 pairs of ribs (HP:0000878) | 1.65077843 |
161 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.64417363 |
162 | Back pain (HP:0003418) | 1.63544205 |
163 | Distal lower limb amyotrophy (HP:0008944) | 1.62348541 |
164 | Preauricular skin tag (HP:0000384) | 1.61916535 |
165 | Renovascular hypertension (HP:0100817) | 1.61842891 |
166 | Unilateral renal agenesis (HP:0000122) | 1.61526945 |
167 | Facial cleft (HP:0002006) | 1.59156462 |
168 | Premature rupture of membranes (HP:0001788) | 1.57571520 |
169 | Abnormality of the carotid arteries (HP:0005344) | 1.55961909 |
170 | Ankyloglossia (HP:0010296) | 1.55922742 |
171 | Progressive hearing impairment (HP:0001730) | 1.55874711 |
172 | Dysphonia (HP:0001618) | 1.55069342 |
173 | High pitched voice (HP:0001620) | 1.54534993 |
174 | Flared metaphyses (HP:0003015) | 1.54313536 |
175 | Skull defect (HP:0001362) | 1.53340808 |
176 | Short middle phalanx of the 5th finger (HP:0004220) | 1.53056940 |
177 | Syringomyelia (HP:0003396) | 1.52897641 |
178 | Spinal cord lesions (HP:0100561) | 1.52897641 |
179 | Pointed chin (HP:0000307) | 1.52552304 |
180 | Neoplasm of the pancreas (HP:0002894) | 1.50963335 |
181 | Shallow orbits (HP:0000586) | 1.50302220 |
182 | Myelodysplasia (HP:0002863) | 1.49971301 |
183 | Reticulocytosis (HP:0001923) | 1.49461979 |
184 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.48590972 |
185 | Cafe-au-lait spot (HP:0000957) | 1.47456927 |
186 | Hypercalcemia (HP:0003072) | 1.46609654 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ICK | 5.07907833 |
2 | SMG1 | 3.94628337 |
3 | DDR2 | 3.94340507 |
4 | MAP3K6 | 3.46397679 |
5 | MAPK15 | 3.03238872 |
6 | VRK2 | 2.77943302 |
7 | MAP3K11 | 2.76385797 |
8 | CDC7 | 2.52331492 |
9 | TYRO3 | 2.49485866 |
10 | CDK7 | 2.18451190 |
11 | MATK | 2.14397894 |
12 | MAP3K10 | 2.12755563 |
13 | IRAK3 | 2.09744045 |
14 | FGR | 2.08141547 |
15 | BMX | 2.05137503 |
16 | PDGFRA | 2.04025290 |
17 | CDK12 | 2.03129067 |
18 | WEE1 | 1.89317375 |
19 | NEK2 | 1.89261933 |
20 | CDK6 | 1.81671952 |
21 | PIM2 | 1.78321679 |
22 | UHMK1 | 1.77320253 |
23 | PBK | 1.76326585 |
24 | DYRK1B | 1.71609882 |
25 | DAPK1 | 1.69176962 |
26 | PRPF4B | 1.62892452 |
27 | TAF1 | 1.58422779 |
28 | DYRK3 | 1.56945238 |
29 | CSK | 1.56704651 |
30 | TRIB3 | 1.54032045 |
31 | EIF2AK1 | 1.51602380 |
32 | YES1 | 1.51308851 |
33 | PINK1 | 1.50419169 |
34 | PRKD2 | 1.46290377 |
35 | PIM1 | 1.45819382 |
36 | RPS6KB2 | 1.44670008 |
37 | PLK1 | 1.38624224 |
38 | EEF2K | 1.37834318 |
39 | LATS2 | 1.37540825 |
40 | CHEK2 | 1.36934370 |
41 | BUB1 | 1.31762769 |
42 | ATR | 1.17774388 |
43 | SIK1 | 1.14086901 |
44 | TRPM7 | 1.10612606 |
45 | MTOR | 1.06800092 |
46 | NEK1 | 1.05821516 |
47 | CDK4 | 1.05059529 |
48 | PKN2 | 1.04820974 |
49 | RPS6KL1 | 1.04054562 |
50 | RPS6KC1 | 1.04054562 |
51 | TTK | 0.98958235 |
52 | LATS1 | 0.98048782 |
53 | MAPK11 | 0.97194268 |
54 | AURKB | 0.96403159 |
55 | ARAF | 0.94717953 |
56 | BRAF | 0.92830234 |
57 | PLK4 | 0.92376374 |
58 | RPS6KA6 | 0.89966741 |
59 | GSK3A | 0.89301237 |
60 | EPHA2 | 0.89094688 |
61 | ALK | 0.88541075 |
62 | CHEK1 | 0.88408456 |
63 | PLK3 | 0.87613397 |
64 | STK3 | 0.87249107 |
65 | STK10 | 0.85749123 |
66 | SCYL2 | 0.83896517 |
67 | CDK2 | 0.83791282 |
68 | MAP3K9 | 0.81274242 |
69 | MST1R | 0.80609284 |
70 | FGFR4 | 0.80161703 |
71 | PAK4 | 0.79717352 |
72 | MKNK1 | 0.79537524 |
73 | TTN | 0.78032018 |
74 | MAP3K8 | 0.77111010 |
75 | DMPK | 0.75499876 |
76 | ACVR1B | 0.73689849 |
77 | KDR | 0.73515772 |
78 | RPS6KA1 | 0.73163139 |
79 | CDC42BPA | 0.72368318 |
80 | AURKA | 0.71969635 |
81 | TESK2 | 0.71710518 |
82 | BRSK2 | 0.70110502 |
83 | ERN1 | 0.69273149 |
84 | ATM | 0.68369498 |
85 | CLK1 | 0.66876138 |
86 | MKNK2 | 0.65119165 |
87 | SRPK1 | 0.64905741 |
88 | VRK1 | 0.63951091 |
89 | TAOK2 | 0.63903895 |
90 | ILK | 0.62903043 |
91 | MAP2K2 | 0.61882642 |
92 | PTK2 | 0.61527539 |
93 | PAK2 | 0.61241251 |
94 | TESK1 | 0.61236866 |
95 | CDK9 | 0.60549554 |
96 | MAP3K13 | 0.58304171 |
97 | STK16 | 0.57624044 |
98 | RPS6KA4 | 0.56153805 |
99 | PTK6 | 0.55147574 |
100 | NME1 | 0.54946946 |
101 | AKT3 | 0.54338207 |
102 | RIPK1 | 0.53773190 |
103 | HIPK2 | 0.52635030 |
104 | CSNK2A1 | 0.52098726 |
105 | CDK1 | 0.51950907 |
106 | FGFR1 | 0.51540066 |
107 | CSNK2A2 | 0.50702296 |
108 | CDK11A | 0.48763016 |
109 | NME2 | 0.47953123 |
110 | PDGFRB | 0.47656837 |
111 | ERBB3 | 0.47654058 |
112 | EIF2AK2 | 0.47625704 |
113 | PASK | 0.46397965 |
114 | FLT3 | 0.46268764 |
115 | CAMK1D | 0.44517511 |
116 | CDK15 | 0.44196897 |
117 | ERBB4 | 0.43967511 |
118 | PNCK | 0.43839317 |
119 | TLK1 | 0.43793108 |
120 | CSNK1E | 0.43087456 |
121 | EGFR | 0.42311821 |
122 | STK4 | 0.41354589 |
123 | LRRK2 | 0.41267371 |
124 | RAF1 | 0.41252216 |
125 | BRD4 | 0.40478212 |
126 | MAPK1 | 0.40288592 |
127 | MELK | 0.39894683 |
128 | MAPK14 | 0.39885316 |
129 | PRKCI | 0.39689690 |
130 | CDK18 | 0.39604859 |
131 | TGFBR1 | 0.38385605 |
132 | MAP4K1 | 0.38123353 |
133 | PRKAA1 | 0.37189668 |
134 | RPS6KB1 | 0.36774815 |
135 | CAMK1G | 0.36486818 |
136 | PAK1 | 0.36376464 |
137 | AKT2 | 0.36123433 |
138 | BRSK1 | 0.34949571 |
139 | CSNK1G1 | 0.34210105 |
140 | TSSK6 | 0.33484961 |
141 | CDK8 | 0.33013393 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Mismatch repair_Homo sapiens_hsa03430 | 4.77402487 |
2 | DNA replication_Homo sapiens_hsa03030 | 4.66117322 |
3 | Base excision repair_Homo sapiens_hsa03410 | 4.03845532 |
4 | Spliceosome_Homo sapiens_hsa03040 | 3.08508981 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.92261436 |
6 | RNA transport_Homo sapiens_hsa03013 | 2.87621278 |
7 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.82617529 |
8 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.64269840 |
9 | Cell cycle_Homo sapiens_hsa04110 | 2.46329107 |
10 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.36196341 |
11 | Homologous recombination_Homo sapiens_hsa03440 | 2.26420124 |
12 | Ribosome_Homo sapiens_hsa03010 | 1.93904301 |
13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.89746201 |
14 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.84790287 |
15 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.83414853 |
16 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.73963595 |
17 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.71640391 |
18 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.67185594 |
19 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.58011587 |
20 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.56423346 |
21 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.51667524 |
22 | Adherens junction_Homo sapiens_hsa04520 | 1.48038090 |
23 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.37500348 |
24 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.32548114 |
25 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.30913639 |
26 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.29313587 |
27 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.26378608 |
28 | Bladder cancer_Homo sapiens_hsa05219 | 1.25978226 |
29 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.25792862 |
30 | Carbon metabolism_Homo sapiens_hsa01200 | 1.24445839 |
31 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.22999570 |
32 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.20585967 |
33 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.14516419 |
34 | RNA polymerase_Homo sapiens_hsa03020 | 1.14103985 |
35 | Colorectal cancer_Homo sapiens_hsa05210 | 1.12888365 |
36 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.10049438 |
37 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.09429031 |
38 | RNA degradation_Homo sapiens_hsa03018 | 1.09348858 |
39 | Sulfur relay system_Homo sapiens_hsa04122 | 1.08830377 |
40 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.08346885 |
41 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.07684353 |
42 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.06104121 |
43 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.03158813 |
44 | Shigellosis_Homo sapiens_hsa05131 | 1.00665540 |
45 | Lysine degradation_Homo sapiens_hsa00310 | 0.99800280 |
46 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.98231679 |
47 | Thyroid cancer_Homo sapiens_hsa05216 | 0.97962095 |
48 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.96634658 |
49 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.87577066 |
50 | Proteasome_Homo sapiens_hsa03050 | 0.87569936 |
51 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.86281579 |
52 | Viral myocarditis_Homo sapiens_hsa05416 | 0.85923192 |
53 | Basal transcription factors_Homo sapiens_hsa03022 | 0.85768626 |
54 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.85756683 |
55 | HTLV-I infection_Homo sapiens_hsa05166 | 0.84954151 |
56 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.83606870 |
57 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.82543582 |
58 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.82069249 |
59 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.80970480 |
60 | Galactose metabolism_Homo sapiens_hsa00052 | 0.80379072 |
61 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.79571203 |
62 | Circadian rhythm_Homo sapiens_hsa04710 | 0.79360817 |
63 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.78224870 |
64 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.77454265 |
65 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.74675322 |
66 | Purine metabolism_Homo sapiens_hsa00230 | 0.73580446 |
67 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.72789243 |
68 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.72078365 |
69 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.70343711 |
70 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.70020010 |
71 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.67739641 |
72 | Tight junction_Homo sapiens_hsa04530 | 0.67006809 |
73 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.66628968 |
74 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.66313573 |
75 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.65453798 |
76 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.65056411 |
77 | Legionellosis_Homo sapiens_hsa05134 | 0.64482411 |
78 | Endometrial cancer_Homo sapiens_hsa05213 | 0.60735153 |
79 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.60244575 |
80 | Hepatitis B_Homo sapiens_hsa05161 | 0.55698342 |
81 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.55411931 |
82 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.55137820 |
83 | Prion diseases_Homo sapiens_hsa05020 | 0.55073058 |
84 | Prostate cancer_Homo sapiens_hsa05215 | 0.53112624 |
85 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.52451334 |
86 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.50818079 |
87 | Pathways in cancer_Homo sapiens_hsa05200 | 0.50529625 |
88 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.49728985 |
89 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.48233068 |
90 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.47416376 |
91 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.47387436 |
92 | Glioma_Homo sapiens_hsa05214 | 0.46397899 |
93 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.46026067 |
94 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.43814048 |
95 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.43584283 |
96 | Focal adhesion_Homo sapiens_hsa04510 | 0.41879300 |
97 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.41772096 |
98 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.39669073 |
99 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.39076911 |
100 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.38269335 |
101 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.38159179 |
102 | Huntingtons disease_Homo sapiens_hsa05016 | 0.37351486 |
103 | Apoptosis_Homo sapiens_hsa04210 | 0.36867061 |
104 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.34835710 |
105 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.34386607 |
106 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.34011892 |
107 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.33740024 |
108 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.32447406 |
109 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.32204458 |
110 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.31753378 |
111 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.31352102 |
112 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.29060061 |
113 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.28257738 |
114 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.27797788 |
115 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.26525518 |
116 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.26255762 |
117 | Measles_Homo sapiens_hsa05162 | 0.25648957 |
118 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.25034590 |
119 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.23216334 |
120 | Melanoma_Homo sapiens_hsa05218 | 0.22636947 |
121 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.22461111 |