HNRNPD

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.07354799
2pre-miRNA processing (GO:0031054)5.02974843
3mitotic sister chromatid cohesion (GO:0007064)4.79943918
4negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.79683581
5establishment of integrated proviral latency (GO:0075713)4.77463084
6protein localization to kinetochore (GO:0034501)4.70914266
7nuclear pore complex assembly (GO:0051292)4.64436670
8nuclear pore organization (GO:0006999)4.63446799
9negative regulation of RNA splicing (GO:0033119)4.33332546
10ribosomal small subunit biogenesis (GO:0042274)4.27792784
11negative regulation of mRNA processing (GO:0050686)4.17859757
12viral transcription (GO:0019083)4.16685106
13sister chromatid segregation (GO:0000819)4.08025991
14translational termination (GO:0006415)4.07261626
15mitotic sister chromatid segregation (GO:0000070)3.91331380
16heterochromatin organization (GO:0070828)3.90662156
17regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.89739963
18protein localization to chromosome, centromeric region (GO:0071459)3.89424030
19mitotic nuclear envelope disassembly (GO:0007077)3.89113534
20maturation of SSU-rRNA (GO:0030490)3.86593957
21nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.82168188
22negative regulation of mRNA metabolic process (GO:1903312)3.82142514
23negative regulation of histone methylation (GO:0031061)3.77421368
24regulation of RNA export from nucleus (GO:0046831)3.70507491
25regulation of sister chromatid cohesion (GO:0007063)3.70376038
26mRNA stabilization (GO:0048255)3.70328607
27RNA stabilization (GO:0043489)3.70328607
28membrane disassembly (GO:0030397)3.70224372
29nuclear envelope disassembly (GO:0051081)3.70224372
30DNA duplex unwinding (GO:0032508)3.62473931
31chromatin remodeling at centromere (GO:0031055)3.60776197
32DNA geometric change (GO:0032392)3.60235894
33ribosomal large subunit biogenesis (GO:0042273)3.58425302
34dosage compensation (GO:0007549)3.55877967
35mitotic chromosome condensation (GO:0007076)3.55401205
36CENP-A containing nucleosome assembly (GO:0034080)3.54145434
37kinetochore organization (GO:0051383)3.53603850
38positive regulation of chromosome segregation (GO:0051984)3.52393201
39mitotic metaphase plate congression (GO:0007080)3.50266165
40glucocorticoid receptor signaling pathway (GO:0042921)3.49592255
41translational initiation (GO:0006413)3.48925575
42ribosomal small subunit assembly (GO:0000028)3.48522290
43positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.47909993
44positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.47909993
45positive regulation of mitotic sister chromatid separation (GO:1901970)3.47909993
46establishment of viral latency (GO:0019043)3.47138594
47telomere maintenance via recombination (GO:0000722)3.45915226
48DNA topological change (GO:0006265)3.44424545
49translational elongation (GO:0006414)3.40495133
50chromosome condensation (GO:0030261)3.40444961
51pore complex assembly (GO:0046931)3.39116985
52IMP metabolic process (GO:0046040)3.33936084
53SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.33471678
54alternative mRNA splicing, via spliceosome (GO:0000380)3.32231373
55regulation of DNA endoreduplication (GO:0032875)3.31092330
56peptidyl-arginine omega-N-methylation (GO:0035247)3.29964769
57DNA strand elongation involved in DNA replication (GO:0006271)3.28441894
58ribosome assembly (GO:0042255)3.27577419
59protein targeting to ER (GO:0045047)3.27225478
60cotranslational protein targeting to membrane (GO:0006613)3.27218626
61regulation of histone H3-K9 methylation (GO:0051570)3.26831009
62DNA ligation (GO:0006266)3.25145611
63ribonucleoprotein complex biogenesis (GO:0022613)3.23490166
64* mRNA splicing, via spliceosome (GO:0000398)3.23248211
65* RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)3.23248211
66protein complex disassembly (GO:0043241)3.23122924
67DNA replication initiation (GO:0006270)3.21833456
68protein complex localization (GO:0031503)3.21199894
69peptidyl-arginine methylation (GO:0018216)3.20962984
70peptidyl-arginine N-methylation (GO:0035246)3.20962984
71cellular protein complex disassembly (GO:0043624)3.20614547
72* RNA splicing, via transesterification reactions (GO:0000375)3.20438842
73purine nucleobase biosynthetic process (GO:0009113)3.20211951
74regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.18989680
75DNA replication-dependent nucleosome assembly (GO:0006335)3.18619838
76DNA replication-dependent nucleosome organization (GO:0034723)3.18619838
77regulation of translational fidelity (GO:0006450)3.18104607
78nucleobase biosynthetic process (GO:0046112)3.17028318
79metaphase plate congression (GO:0051310)3.15809086
80viral life cycle (GO:0019058)3.15224289
81establishment of protein localization to endoplasmic reticulum (GO:0072599)3.15032450
82formation of translation preinitiation complex (GO:0001731)3.14850029
83spliceosomal tri-snRNP complex assembly (GO:0000244)3.13031345
843-UTR-mediated mRNA stabilization (GO:0070935)3.12557814
85DNA strand elongation (GO:0022616)3.11973738
86protein-DNA complex disassembly (GO:0032986)3.09006379
87nucleosome disassembly (GO:0006337)3.09006379
88V(D)J recombination (GO:0033151)3.08324677
89termination of RNA polymerase II transcription (GO:0006369)3.07179730
90histone exchange (GO:0043486)3.06591887
91protein localization to chromosome (GO:0034502)3.05006452
92macromolecular complex disassembly (GO:0032984)3.03296824
93chromatin assembly (GO:0031497)3.02691068
94ATP-dependent chromatin remodeling (GO:0043044)3.02394118
95regulation of spindle organization (GO:0090224)2.99522793
96IMP biosynthetic process (GO:0006188)2.98756857
97DNA synthesis involved in DNA repair (GO:0000731)2.98595681
98mRNA transport (GO:0051028)2.97834625
99chromatin assembly or disassembly (GO:0006333)2.96731039
100DNA conformation change (GO:0071103)2.96485333
101protein localization to endoplasmic reticulum (GO:0070972)2.95396152
102nuclear envelope organization (GO:0006998)2.94918228
103kinetochore assembly (GO:0051382)2.93502008
104DNA packaging (GO:0006323)2.92692057
105regulation of chromosome segregation (GO:0051983)2.89306641
106regulation of translational termination (GO:0006449)2.89115009
107mRNA splice site selection (GO:0006376)2.88853956
108DNA replication checkpoint (GO:0000076)2.88708447
109regulation of DNA damage checkpoint (GO:2000001)2.88534292
110positive regulation of histone H3-K4 methylation (GO:0051571)2.88080549
111* regulation of mRNA stability (GO:0043488)2.87907255
112regulation of gene silencing by miRNA (GO:0060964)2.87897176
113regulation of gene silencing by RNA (GO:0060966)2.87897176
114regulation of posttranscriptional gene silencing (GO:0060147)2.87897176
115regulation of nucleobase-containing compound transport (GO:0032239)2.87251230
116folic acid-containing compound biosynthetic process (GO:0009396)2.86635057
117NLS-bearing protein import into nucleus (GO:0006607)2.86504540
118regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.85996447
119attachment of spindle microtubules to kinetochore (GO:0008608)2.84339509
120RNA export from nucleus (GO:0006405)2.83669552
121establishment of chromosome localization (GO:0051303)2.83352120
122paraxial mesoderm development (GO:0048339)2.81681562
123DNA replication-independent nucleosome organization (GO:0034724)2.81460501
124DNA replication-independent nucleosome assembly (GO:0006336)2.81460501
125intracellular estrogen receptor signaling pathway (GO:0030520)2.81332582
126peptidyl-lysine dimethylation (GO:0018027)2.80556195
127regulation of centriole replication (GO:0046599)2.79945623
128regulation of mitotic metaphase/anaphase transition (GO:0030071)2.78256520
129mitotic recombination (GO:0006312)2.78218776
130mRNA export from nucleus (GO:0006406)2.78016576
131regulation of centrosome cycle (GO:0046605)2.77766283
132RNA transport (GO:0050658)2.77741298
133establishment of RNA localization (GO:0051236)2.77741298
134nucleic acid transport (GO:0050657)2.77741298
135telomere maintenance via semi-conservative replication (GO:0032201)2.77098119
136regulation of stem cell maintenance (GO:2000036)2.76040616

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human6.00256320
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.14626059
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.89403319
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.56173420
5* MYC_22102868_ChIP-Seq_BL_Human3.34966382
6* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.31363158
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.95381770
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.87088250
9* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.72817132
10E2F1_21310950_ChIP-Seq_MCF-7_Human2.35935509
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.33401882
12TP63_19390658_ChIP-ChIP_HaCaT_Human2.31810548
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.26055964
14AR_21909140_ChIP-Seq_LNCAP_Human2.24308988
15ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.07674087
16XRN2_22483619_ChIP-Seq_HELA_Human2.02335762
17E2F7_22180533_ChIP-Seq_HELA_Human10.2251940
18KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.85324171
19SALL1_21062744_ChIP-ChIP_HESCs_Human1.85117830
20* CIITA_25753668_ChIP-Seq_RAJI_Human1.83545349
21MYC_18358816_ChIP-ChIP_MESCs_Mouse1.78813807
22VDR_21846776_ChIP-Seq_THP-1_Human1.78661917
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.78261471
24NELFA_20434984_ChIP-Seq_ESCs_Mouse1.77163268
25MYCN_18555785_ChIP-Seq_MESCs_Mouse1.74084595
26MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.60348712
27SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.59919125
28SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.58356013
29CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.58264926
30KDM5A_27292631_Chip-Seq_BREAST_Human1.56439793
31YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.53978180
32POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.53526132
33* TCF7_22412390_ChIP-Seq_EML_Mouse1.52111741
34* TTF2_22483619_ChIP-Seq_HELA_Human1.51398662
35JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.48163213
36ZFP281_18757296_ChIP-ChIP_E14_Mouse1.45088933
37RBPJ_22232070_ChIP-Seq_NCS_Mouse1.44688634
38ZFP281_27345836_Chip-Seq_ESCs_Mouse1.44427990
39KDM2B_26808549_Chip-Seq_DND41_Human1.41128564
40ZFX_18555785_ChIP-Seq_MESCs_Mouse1.39231752
41KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.39042688
42ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.38485929
43NANOG_21062744_ChIP-ChIP_HESCs_Human1.37245772
44KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.36459276
45ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.34098436
46NANOG_18555785_ChIP-Seq_MESCs_Mouse1.34020569
47HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.33943645
48CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.33749518
49ESR1_15608294_ChIP-ChIP_MCF-7_Human1.32779699
50DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.30973612
51SOX2_18555785_ChIP-Seq_MESCs_Mouse1.29131463
52HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.29053730
53ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.28406902
54EST1_17652178_ChIP-ChIP_JURKAT_Human1.27845036
55KLF4_18555785_ChIP-Seq_MESCs_Mouse1.27551903
56PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.27405375
57PKCTHETA_26484144_Chip-Seq_BREAST_Human1.26761233
58MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25938160
59* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.25320840
60POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.25152851
61ETS1_20019798_ChIP-Seq_JURKAT_Human1.24963749
62TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.23872687
63GABP_17652178_ChIP-ChIP_JURKAT_Human1.20810362
64* CHD1_26751641_Chip-Seq_LNCaP_Human1.16677347
65TCF3_18692474_ChIP-Seq_MEFs_Mouse1.16584361
66CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.16389830
67GABP_19822575_ChIP-Seq_HepG2_Human1.15699089
68DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.15197139
69FOXP3_21729870_ChIP-Seq_TREG_Human1.14848323
70CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.14421365
71FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.14047758
72CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.13937867
73CREB1_15753290_ChIP-ChIP_HEK293T_Human1.13338285
74TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.12967366
75VDR_23849224_ChIP-Seq_CD4+_Human1.12352942
76UTX_26944678_Chip-Seq_JUKART_Human1.11347589
77KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.10816523
78THAP11_20581084_ChIP-Seq_MESCs_Mouse1.10803264
79E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08647043
80ELF1_17652178_ChIP-ChIP_JURKAT_Human1.08312209
81PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.07112675
82HOXB4_20404135_ChIP-ChIP_EML_Mouse1.06796404
83KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.06361730
84KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.06361730
85KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.06361730
86ERG_20887958_ChIP-Seq_HPC-7_Mouse1.06014734
87SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.05179464
88ELK1_19687146_ChIP-ChIP_HELA_Human1.03768598
89YY1_21170310_ChIP-Seq_MESCs_Mouse1.03058793
90STAT6_21828071_ChIP-Seq_BEAS2B_Human1.00488542
91FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.99784055
92MAF_26560356_Chip-Seq_TH1_Human0.98545446
93KDM2B_26808549_Chip-Seq_JURKAT_Human0.97756942
94ELK3_25401928_ChIP-Seq_HUVEC_Human0.97279538
95TCF3_18692474_ChIP-Seq_MESCs_Mouse0.96502486
96NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.96470732
97ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.96218185
98E2F1_18555785_ChIP-Seq_MESCs_Mouse0.96165529
99TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.95770820
100NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.95591922
101SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.95484097
102DCP1A_22483619_ChIP-Seq_HELA_Human0.95216329
103BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.95073608
104GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.94979891
105POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.94433554
106KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.93861540
107STAT3_1855785_ChIP-Seq_MESCs_Mouse0.93780253
108EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.93655305
109TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.93624738
110KDM2B_26808549_Chip-Seq_SUP-B15_Human0.93183331
111CLOCK_20551151_ChIP-Seq_293T_Human0.92684674
112KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.91856113
113NCOR1_26117541_ChIP-Seq_K562_Human0.91203243
114PADI4_21655091_ChIP-ChIP_MCF-7_Human0.90942515
115SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.90498639
116POU5F1_16518401_ChIP-PET_MESCs_Mouse0.90233921
117SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.90137927
118SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.89870526
119NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.89162407
120E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.87365973
121OCT4_18692474_ChIP-Seq_MEFs_Mouse0.87125889
122SOX2_16153702_ChIP-ChIP_HESCs_Human0.85553801

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003111_abnormal_nucleus_morphology3.59206522
2MP0010094_abnormal_chromosome_stability3.55604734
3MP0008057_abnormal_DNA_replication3.47811637
4MP0003693_abnormal_embryo_hatching3.42164100
5MP0004957_abnormal_blastocyst_morpholog3.38369657
6MP0003123_paternal_imprinting3.26762696
7MP0003077_abnormal_cell_cycle3.06483260
8MP0010352_gastrointestinal_tract_polyps2.73826989
9MP0005076_abnormal_cell_differentiation2.68587670
10MP0009379_abnormal_foot_pigmentation2.52520501
11MP0003121_genomic_imprinting2.40501192
12MP0001730_embryonic_growth_arrest2.32238986
13MP0000537_abnormal_urethra_morphology2.20119508
14MP0010030_abnormal_orbit_morphology2.18022605
15MP0000350_abnormal_cell_proliferation2.17551637
16MP0003705_abnormal_hypodermis_morpholog2.16846987
17MP0002396_abnormal_hematopoietic_system2.08548722
18MP0002084_abnormal_developmental_patter2.07609548
19MP0003890_abnormal_embryonic-extraembry2.05816036
20MP0009053_abnormal_anal_canal2.05514834
21MP0005380_embryogenesis_phenotype2.00632306
22MP0001672_abnormal_embryogenesis/_devel2.00632306
23* MP0004197_abnormal_fetal_growth/weight/1.94390388
24MP0008058_abnormal_DNA_repair1.92564492
25MP0002085_abnormal_embryonic_tissue1.91766159
26MP0001697_abnormal_embryo_size1.91573990
27MP0008007_abnormal_cellular_replicative1.87646278
28MP0003984_embryonic_growth_retardation1.86202204
29MP0008932_abnormal_embryonic_tissue1.84857938
30MP0002088_abnormal_embryonic_growth/wei1.84378724
31MP0003567_abnormal_fetal_cardiomyocyte1.83630778
32MP0008877_abnormal_DNA_methylation1.81028614
33MP0002086_abnormal_extraembryonic_tissu1.77971441
34MP0003787_abnormal_imprinting1.75671478
35MP0003122_maternal_imprinting1.73250520
36MP0010307_abnormal_tumor_latency1.71245318
37MP0000566_synostosis1.68718078
38MP0003119_abnormal_digestive_system1.66186473
39MP0004185_abnormal_adipocyte_glucose1.66174197
40MP0004808_abnormal_hematopoietic_stem1.61499021
41MP0002080_prenatal_lethality1.60714123
42MP0001293_anophthalmia1.59702458
43MP0009278_abnormal_bone_marrow1.53549902
44MP0002877_abnormal_melanocyte_morpholog1.47686226
45MP0002009_preneoplasia1.40785790
46MP0009697_abnormal_copulation1.35592413
47MP0000428_abnormal_craniofacial_morphol1.32649543
48MP0001188_hyperpigmentation1.32599467
49MP0000569_abnormal_digit_pigmentation1.30562195
50MP0000490_abnormal_crypts_of1.25531591
51* MP0009703_decreased_birth_body1.23715689
52MP0002653_abnormal_ependyma_morphology1.22780845
53MP0003935_abnormal_craniofacial_develop1.20898260
54MP0000703_abnormal_thymus_morphology1.17095266
55MP0001346_abnormal_lacrimal_gland1.16900476
56MP0004233_abnormal_muscle_weight1.14926547
57MP0003115_abnormal_respiratory_system1.14875679
58MP0000313_abnormal_cell_death1.14400577
59MP0003861_abnormal_nervous_system1.13378060
60MP0000733_abnormal_muscle_development1.12982334
61* MP0009672_abnormal_birth_weight1.12811922
62MP0003385_abnormal_body_wall1.10069836
63MP0001849_ear_inflammation1.09760737
64MP0005187_abnormal_penis_morphology1.07063250
65MP0003937_abnormal_limbs/digits/tail_de1.05625132
66MP0002796_impaired_skin_barrier1.04978330
67MP0001545_abnormal_hematopoietic_system1.04150035
68MP0005397_hematopoietic_system_phenotyp1.04150035
69MP0002925_abnormal_cardiovascular_devel1.03382658
70MP0002019_abnormal_tumor_incidence1.02371486
71MP0006292_abnormal_olfactory_placode1.00584007
72MP0002092_abnormal_eye_morphology1.00525811
73MP0000516_abnormal_urinary_system1.00061066
74MP0005367_renal/urinary_system_phenotyp1.00061066
75MP0000432_abnormal_head_morphology1.00016342
76MP0002697_abnormal_eye_size0.98107232
77MP0003755_abnormal_palate_morphology0.97532960
78MP0001286_abnormal_eye_development0.96196188
79MP0000678_abnormal_parathyroid_gland0.95753955
80MP0002932_abnormal_joint_morphology0.95684762
81MP0003315_abnormal_perineum_morphology0.93248380
82MP0002111_abnormal_tail_morphology0.92001639
83MP0005501_abnormal_skin_physiology0.91837934
84MP0003283_abnormal_digestive_organ0.91669051
85MP0003942_abnormal_urinary_system0.91540148
86MP0010234_abnormal_vibrissa_follicle0.89744228
87MP0008770_decreased_survivor_rate0.89691148
88MP0004264_abnormal_extraembryonic_tissu0.87704293
89MP0003718_maternal_effect0.87349677
90MP0003303_peritoneal_inflammation0.86877937
91MP0000049_abnormal_middle_ear0.86800831
92MP0002116_abnormal_craniofacial_bone0.86460600
93MP0002089_abnormal_postnatal_growth/wei0.84972178
94MP0001915_intracranial_hemorrhage0.84724309
95MP0002114_abnormal_axial_skeleton0.84013961
96MP0002081_perinatal_lethality0.81707057
97MP0003943_abnormal_hepatobiliary_system0.79023198
98MP0005623_abnormal_meninges_morphology0.78336096
99MP0010630_abnormal_cardiac_muscle0.77927440
100MP0002398_abnormal_bone_marrow0.77460714
101MP0000534_abnormal_ureter_morphology0.76500078
102MP0002938_white_spotting0.75611913
103MP0003941_abnormal_skin_development0.75045557
104MP0000266_abnormal_heart_morphology0.74805690
105MP0003566_abnormal_cell_adhesion0.73322583
106MP0005621_abnormal_cell_physiology0.73220470
107MP0002249_abnormal_larynx_morphology0.71931735
108MP0003763_abnormal_thymus_physiology0.71773276
109MP0008789_abnormal_olfactory_epithelium0.71413700
110MP0005384_cellular_phenotype0.71407569
111MP0003786_premature_aging0.71362923
112MP0001784_abnormal_fluid_regulation0.70994872
113MP0005248_abnormal_Harderian_gland0.70927461
114MP0002233_abnormal_nose_morphology0.70299386
115MP0005394_taste/olfaction_phenotype0.69985821
116MP0005499_abnormal_olfactory_system0.69985821
117MP0003938_abnormal_ear_development0.69166722
118MP0002210_abnormal_sex_determination0.68527923
119MP0005666_abnormal_adipose_tissue0.68218749
120MP0001145_abnormal_male_reproductive0.65089357
121MP0001881_abnormal_mammary_gland0.63032266
122MP0001340_abnormal_eyelid_morphology0.60556191
123MP0008995_early_reproductive_senescence0.60161767
124MP0003221_abnormal_cardiomyocyte_apopto0.59900023
125MP0000477_abnormal_intestine_morphology0.59032531
126MP0006035_abnormal_mitochondrial_morpho0.58397828

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.03931829
2Reticulocytopenia (HP:0001896)3.82998653
3Volvulus (HP:0002580)3.58148810
4Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.48475273
5Short 4th metacarpal (HP:0010044)3.48475273
6Increased nuchal translucency (HP:0010880)3.40654962
7Abnormality of cells of the erythroid lineage (HP:0012130)3.23574317
8Ependymoma (HP:0002888)3.15433033
9Renal duplication (HP:0000075)3.12154168
10Hyperacusis (HP:0010780)3.02161179
11Medulloblastoma (HP:0002885)2.95905722
12Colon cancer (HP:0003003)2.92465002
13Macrocytic anemia (HP:0001972)2.90578692
14Multiple enchondromatosis (HP:0005701)2.78146802
15Abnormal number of incisors (HP:0011064)2.76818613
16Nephroblastoma (Wilms tumor) (HP:0002667)2.75626317
17Proximal placement of thumb (HP:0009623)2.72698646
18Pallor (HP:0000980)2.70386403
19Deviation of the thumb (HP:0009603)2.66625907
20Abnormality of the 4th metacarpal (HP:0010012)2.66401037
21Abnormality of the astrocytes (HP:0100707)2.65536586
22Astrocytoma (HP:0009592)2.65536586
23Selective tooth agenesis (HP:0001592)2.65063889
24Cortical dysplasia (HP:0002539)2.64523785
25Abnormal number of erythroid precursors (HP:0012131)2.62920448
26Abnormality of the labia minora (HP:0012880)2.55620399
27Embryonal renal neoplasm (HP:0011794)2.52916682
28Long eyelashes (HP:0000527)2.49436626
29Facial hemangioma (HP:0000329)2.44643810
30Progressive muscle weakness (HP:0003323)2.42897060
31Patellar aplasia (HP:0006443)2.40722347
32Rhabdomyosarcoma (HP:0002859)2.38071686
33Supernumerary ribs (HP:0005815)2.37589159
34Rib fusion (HP:0000902)2.37225094
35Acute myeloid leukemia (HP:0004808)2.36877509
36Deep palmar crease (HP:0006191)2.35514475
37Basal cell carcinoma (HP:0002671)2.35102838
38Duplication of thumb phalanx (HP:0009942)2.33685235
39Missing ribs (HP:0000921)2.32492601
40Abnormality of the fingertips (HP:0001211)2.32248403
41Atresia of the external auditory canal (HP:0000413)2.31594325
42Neoplasm of striated muscle (HP:0009728)2.31335375
43Abnormality of cochlea (HP:0000375)2.29359159
44Aplasia/Hypoplasia of the patella (HP:0006498)2.29197669
45Broad thumb (HP:0011304)2.22339125
46Glioma (HP:0009733)2.22090665
47Broad palm (HP:0001169)2.21648366
48Elfin facies (HP:0004428)2.21622179
49Supernumerary bones of the axial skeleton (HP:0009144)2.19629830
50Neoplasm of the oral cavity (HP:0100649)2.19345244
51Renovascular hypertension (HP:0100817)2.19284284
52Abnormality of the ileum (HP:0001549)2.18557656
53Horseshoe kidney (HP:0000085)2.18452651
54Short middle phalanx of the 5th finger (HP:0004220)2.17549801
55Overriding aorta (HP:0002623)2.16472771
56Partial duplication of thumb phalanx (HP:0009944)2.16355594
57Progressive external ophthalmoplegia (HP:0000590)2.16143381
58Abnormality of the preputium (HP:0100587)2.14894435
59Septo-optic dysplasia (HP:0100842)2.14087293
60Aplasia/Hypoplasia of the sacrum (HP:0008517)2.12250445
61Skin tags (HP:0010609)2.11927040
62Absent radius (HP:0003974)2.10452190
63Prominent nose (HP:0000448)2.10412363
64Obsessive-compulsive behavior (HP:0000722)2.09392858
65Trigonocephaly (HP:0000243)2.08573236
66Pointed chin (HP:0000307)2.07294354
67Ectopic kidney (HP:0000086)2.05581790
68Birth length less than 3rd percentile (HP:0003561)2.02766243
69Aplasia/Hypoplasia of the sternum (HP:0006714)2.02550567
70Rectal prolapse (HP:0002035)2.01875938
71Abnormal lung lobation (HP:0002101)2.00943572
72Triphalangeal thumb (HP:0001199)1.99495430
73Gastrointestinal carcinoma (HP:0002672)1.99286473
74Malignant gastrointestinal tract tumors (HP:0006749)1.99286473
75Cutis marmorata (HP:0000965)1.99024736
76Shallow orbits (HP:0000586)1.97230701
77Pseudobulbar signs (HP:0002200)1.97158180
78Macroorchidism (HP:0000053)1.96916359
79Partial duplication of the phalanx of hand (HP:0009999)1.95851746
80Microvesicular hepatic steatosis (HP:0001414)1.95781799
81Sacral dimple (HP:0000960)1.95143492
82Homocystinuria (HP:0002156)1.93903236
83Abnormality of homocysteine metabolism (HP:0010919)1.93903236
84Absent forearm bone (HP:0003953)1.93346699
85Aplasia involving forearm bones (HP:0009822)1.93346699
86Ankyloglossia (HP:0010296)1.93210615
8711 pairs of ribs (HP:0000878)1.92564294
88Abnormality of the diencephalon (HP:0010662)1.92542620
89Abnormality of the parietal bone (HP:0002696)1.92428481
90Preauricular skin tag (HP:0000384)1.91481271
91Pelvic girdle muscle weakness (HP:0003749)1.91418879
92High anterior hairline (HP:0009890)1.91047608
93Abnormality of the calcaneus (HP:0008364)1.90653013
94Intestinal fistula (HP:0100819)1.89891827
95Breast hypoplasia (HP:0003187)1.89129174
96Overlapping toe (HP:0001845)1.89102336
97Insomnia (HP:0100785)1.88362740
98Diastasis recti (HP:0001540)1.87279842
99Abnormality of reticulocytes (HP:0004312)1.86662811
100Aplasia/Hypoplasia of the uvula (HP:0010293)1.86363499
101High pitched voice (HP:0001620)1.86151862
102Short phalanx of the thumb (HP:0009660)1.86007260
103Rectal fistula (HP:0100590)1.84809486
104Rectovaginal fistula (HP:0000143)1.84809486
105Annular pancreas (HP:0001734)1.84656275
106Embryonal neoplasm (HP:0002898)1.84328482
107Heterotopia (HP:0002282)1.83420745
108Chromsome breakage (HP:0040012)1.83294125
109Duodenal stenosis (HP:0100867)1.82675556
110Small intestinal stenosis (HP:0012848)1.82675556
111Broad phalanges of the hand (HP:0009768)1.81740609
112Dysphonia (HP:0001618)1.80393434
113Abnormality of the septum pellucidum (HP:0007375)1.80137582
114Deep philtrum (HP:0002002)1.79401001
115Abnormality of chromosome segregation (HP:0002916)1.79359035
116Short 1st metacarpal (HP:0010034)1.78755343
117Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.78755343
118Increased density of long bones (HP:0006392)1.78223810
119Short 5th finger (HP:0009237)1.77589519
120Acute lymphatic leukemia (HP:0006721)1.76625918
121Morphological abnormality of the inner ear (HP:0011390)1.74762650
122Impulsivity (HP:0100710)1.74685037
123Choanal atresia (HP:0000453)1.74331800
124Skull defect (HP:0001362)1.73537945
125Calcaneovalgus deformity (HP:0001848)1.72832853
126Abnormality of the salivary glands (HP:0010286)1.71864446
127Shawl scrotum (HP:0000049)1.71494347
128Bowel diverticulosis (HP:0005222)1.70984568
129Truncal obesity (HP:0001956)1.69754788
130Cafe-au-lait spot (HP:0000957)1.69676039
131Long palpebral fissure (HP:0000637)1.69449951
132Spina bifida occulta (HP:0003298)1.68570239
133Urethral obstruction (HP:0000796)1.68070267
134Chin dimple (HP:0010751)1.67329488
135Shoulder girdle muscle weakness (HP:0003547)1.67086088
136Spastic diplegia (HP:0001264)1.66982399
137Broad finger (HP:0001500)1.65652186
138Vertebral arch anomaly (HP:0008438)1.65440676
139Syringomyelia (HP:0003396)1.64726325
140Spinal cord lesions (HP:0100561)1.64726325
141Meckel diverticulum (HP:0002245)1.64239203
142Abnormality of chromosome stability (HP:0003220)1.64006275
143Bilateral microphthalmos (HP:0007633)1.63979492
144Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.63369726
145Deviation of the hallux (HP:0010051)1.63283915
146Megalocornea (HP:0000485)1.62849327
147Oligodactyly (HP:0012165)1.62496950
148Tracheoesophageal fistula (HP:0002575)1.62005578
149Low anterior hairline (HP:0000294)1.61928033
150Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.61833594
151Flat cornea (HP:0007720)1.61637374
152Myelodysplasia (HP:0002863)1.61529480
153Intestinal polyp (HP:0005266)1.61477572
154Abnormality of the carotid arteries (HP:0005344)1.61298936
155Abdominal situs inversus (HP:0003363)1.60974807
156Abnormality of abdominal situs (HP:0011620)1.60974807
157Sandal gap (HP:0001852)1.60929255

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.59717027
2CDK124.42448548
3SMG13.18731820
4MAP3K103.12156517
5NEK22.98849198
6EEF2K2.83084522
7VRK22.79290200
8MKNK12.31999185
9TAF12.31057982
10PKN22.29935815
11WEE12.29761912
12ALK2.20462832
13NEK12.16586130
14BRD42.12516164
15MKNK21.95953410
16TTK1.94970265
17TRIB31.81631728
18CDK41.79804653
19SRPK11.74919912
20CDK61.73714173
21TSSK61.67983350
22CDK71.65197210
23ATR1.62480544
24RPS6KB21.49784653
25CHEK11.49396645
26BUB11.47771532
27TNIK1.47579511
28PLK11.44078381
29PRPF4B1.39173857
30PLK31.37957828
31STK101.36092116
32CHEK21.32717744
33SCYL21.31790123
34ICK1.31764756
35LATS21.28563683
36PASK1.27845356
37RPS6KA41.26739123
38LATS11.23252515
39MTOR1.16169068
40SIK21.16094804
41AURKB1.15705628
42* CDK21.15338431
43NME21.11944200
44MAP3K81.11147605
45PAK41.10256740
46ATM1.09833558
47TYRO31.09800744
48BRSK21.07613484
49PNCK1.05280577
50STK31.01256384
51BRSK11.01251875
52TAOK10.97567116
53PTK60.95890852
54PDGFRA0.95882525
55PBK0.93966426
56DYRK30.91639521
57NME10.91437285
58MAP3K130.91384923
59TGFBR10.91189259
60FGFR10.90078074
61ERBB30.89244041
62VRK10.87874680
63EIF2AK10.86668495
64* CDK10.84727189
65FGFR40.81184984
66BMX0.80383453
67MAP4K10.80304916
68MAP3K90.76564382
69CSNK1E0.73042204
70PLK40.71097822
71LRRK20.70727277
72CDK30.69863070
73STK240.69195890
74EIF2AK20.68929830
75GRK60.67178373
76CDK190.65817738
77ACVR1B0.64381914
78RIPK10.63283133
79TESK20.63073328
80PRKDC0.62599107
81STK40.62291039
82DMPK0.60472692
83AURKA0.59604995
84CSNK1D0.59432837
85CDK80.59070572
86PAK20.58779823
87MELK0.58500298
88* MAPK140.57730227
89CAMK1G0.57446646
90PIM10.57246405
91UHMK10.56743919
92BRAF0.56634673
93KSR10.56612156
94AKT20.55619061
95CSNK2A20.52306514
96CAMK1D0.51216151
97DDR20.48961779
98CDK150.47547071
99* GSK3B0.47349593
100RPS6KA10.46452351
101MAP3K60.46152195
102MAPK100.44410280
103CDK180.43763091
104CDK90.43110948
105AKT10.42197641
106YES10.41400711
107CLK10.41211665
108KSR20.40964402
109DAPK10.40945015
110SIK10.40827301
111MAP3K140.39347270
112MAPK80.39078882
113NLK0.38675087
114TAOK20.38030531
115MAP2K20.37738206
116MAPK10.37605819
117PRKD30.37218204
118CDK140.36682221
119MAPK90.36306027
120CDK11A0.36121166
121CSNK1A1L0.35470603
122RPS6KB10.35430153
123DYRK20.35429678
124CSNK2A10.35184587
125PDGFRB0.35004683
126ILK0.34492348
127ERBB20.33311752
128FGFR20.31234306

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.53750547
2Spliceosome_Homo sapiens_hsa030403.25237347
3Mismatch repair_Homo sapiens_hsa034303.03472678
4RNA transport_Homo sapiens_hsa030132.93476066
5Cell cycle_Homo sapiens_hsa041102.70785857
6mRNA surveillance pathway_Homo sapiens_hsa030152.67689192
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.53871782
8Base excision repair_Homo sapiens_hsa034102.23514078
9One carbon pool by folate_Homo sapiens_hsa006701.80294921
10Homologous recombination_Homo sapiens_hsa034401.77952759
11Nucleotide excision repair_Homo sapiens_hsa034201.74900414
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.59483092
13RNA degradation_Homo sapiens_hsa030181.55363045
14Oocyte meiosis_Homo sapiens_hsa041141.55061399
15Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.52403633
16Fanconi anemia pathway_Homo sapiens_hsa034601.50356383
17Chronic myeloid leukemia_Homo sapiens_hsa052201.47743452
18MicroRNAs in cancer_Homo sapiens_hsa052061.46731111
19Colorectal cancer_Homo sapiens_hsa052101.46504080
20Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.45867384
21Basal cell carcinoma_Homo sapiens_hsa052171.44537954
22Hippo signaling pathway_Homo sapiens_hsa043901.36006628
23Proteasome_Homo sapiens_hsa030501.35843270
24mTOR signaling pathway_Homo sapiens_hsa041501.33678125
25HTLV-I infection_Homo sapiens_hsa051661.28867209
26Non-homologous end-joining_Homo sapiens_hsa034501.25460179
27p53 signaling pathway_Homo sapiens_hsa041151.24447782
28Biosynthesis of amino acids_Homo sapiens_hsa012301.24229085
29Ribosome_Homo sapiens_hsa030101.21770316
30Thyroid cancer_Homo sapiens_hsa052161.21357835
31Non-small cell lung cancer_Homo sapiens_hsa052231.19318713
32Adherens junction_Homo sapiens_hsa045201.16595798
33Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.16322688
34Endometrial cancer_Homo sapiens_hsa052131.15678260
35Cysteine and methionine metabolism_Homo sapiens_hsa002701.13021980
36Notch signaling pathway_Homo sapiens_hsa043301.11629942
37Hedgehog signaling pathway_Homo sapiens_hsa043401.10676720
38Small cell lung cancer_Homo sapiens_hsa052221.05851383
39Epstein-Barr virus infection_Homo sapiens_hsa051691.05220886
40Wnt signaling pathway_Homo sapiens_hsa043101.03400854
41Transcriptional misregulation in cancer_Homo sapiens_hsa052021.02039941
42Antigen processing and presentation_Homo sapiens_hsa046121.01684923
43Viral carcinogenesis_Homo sapiens_hsa052031.01043376
44Glioma_Homo sapiens_hsa052140.99239053
45Herpes simplex infection_Homo sapiens_hsa051680.98857232
46Thyroid hormone signaling pathway_Homo sapiens_hsa049190.97883935
47Neurotrophin signaling pathway_Homo sapiens_hsa047220.97687690
48TGF-beta signaling pathway_Homo sapiens_hsa043500.97547922
49Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.97027646
50Selenocompound metabolism_Homo sapiens_hsa004500.96335501
51Lysine degradation_Homo sapiens_hsa003100.93807046
52Proteoglycans in cancer_Homo sapiens_hsa052050.93303153
53RNA polymerase_Homo sapiens_hsa030200.92278050
54Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.91770319
55Basal transcription factors_Homo sapiens_hsa030220.90814472
56Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.88022687
57Pancreatic cancer_Homo sapiens_hsa052120.86552830
58Acute myeloid leukemia_Homo sapiens_hsa052210.85131530
59Prostate cancer_Homo sapiens_hsa052150.84699917
60Viral myocarditis_Homo sapiens_hsa054160.83714355
61Bladder cancer_Homo sapiens_hsa052190.82685306
62Central carbon metabolism in cancer_Homo sapiens_hsa052300.81748418
63Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.80886358
64Hepatitis B_Homo sapiens_hsa051610.79589149
65Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.78710881
66Purine metabolism_Homo sapiens_hsa002300.78350421
67Pathways in cancer_Homo sapiens_hsa052000.77788703
68Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.77146317
69B cell receptor signaling pathway_Homo sapiens_hsa046620.76609057
70Pyrimidine metabolism_Homo sapiens_hsa002400.75862754
71Pentose phosphate pathway_Homo sapiens_hsa000300.74394106
72Protein export_Homo sapiens_hsa030600.72955330
73Renal cell carcinoma_Homo sapiens_hsa052110.72704276
74Carbon metabolism_Homo sapiens_hsa012000.70589841
75VEGF signaling pathway_Homo sapiens_hsa043700.70149958
76Estrogen signaling pathway_Homo sapiens_hsa049150.69161272
772-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.68280230
78T cell receptor signaling pathway_Homo sapiens_hsa046600.66686283
79Primary immunodeficiency_Homo sapiens_hsa053400.65459708
80Dorso-ventral axis formation_Homo sapiens_hsa043200.64244145
81ErbB signaling pathway_Homo sapiens_hsa040120.62272797
82HIF-1 signaling pathway_Homo sapiens_hsa040660.60286613
83FoxO signaling pathway_Homo sapiens_hsa040680.59533450
84Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.59513143
85Long-term potentiation_Homo sapiens_hsa047200.58175281
86Shigellosis_Homo sapiens_hsa051310.57931200
87AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.57806352
88Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.54983503
89Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54946575
90Tight junction_Homo sapiens_hsa045300.54656016
91Pyruvate metabolism_Homo sapiens_hsa006200.53972934
92Melanogenesis_Homo sapiens_hsa049160.53147153
93Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52749915
94MAPK signaling pathway_Homo sapiens_hsa040100.52056308
95Focal adhesion_Homo sapiens_hsa045100.51579105
96Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.51464849
97Folate biosynthesis_Homo sapiens_hsa007900.51377841
98Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.51030768
99Melanoma_Homo sapiens_hsa052180.50639092
100Leukocyte transendothelial migration_Homo sapiens_hsa046700.48084224
101Gap junction_Homo sapiens_hsa045400.47874794
102Rap1 signaling pathway_Homo sapiens_hsa040150.47163325
103Apoptosis_Homo sapiens_hsa042100.46586590
104Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.46580426
105Prolactin signaling pathway_Homo sapiens_hsa049170.43869664
106Platelet activation_Homo sapiens_hsa046110.43222307
107Insulin signaling pathway_Homo sapiens_hsa049100.42207308
108Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.42050659
109Axon guidance_Homo sapiens_hsa043600.41355860
110AMPK signaling pathway_Homo sapiens_hsa041520.35290564
111PI3K-Akt signaling pathway_Homo sapiens_hsa041510.34769263
112Choline metabolism in cancer_Homo sapiens_hsa052310.34450347
113Measles_Homo sapiens_hsa051620.33397170
114GnRH signaling pathway_Homo sapiens_hsa049120.32785735
115Huntingtons disease_Homo sapiens_hsa050160.32755617
116Dopaminergic synapse_Homo sapiens_hsa047280.32507808
117Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.32119805
118Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.31421494
119Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.31197282
120Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.29911689
121Prion diseases_Homo sapiens_hsa050200.27390342
122Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.18221489
123Sulfur relay system_Homo sapiens_hsa041220.16870223

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