

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.42932636 |
| 2 | rRNA methylation (GO:0031167) | 5.31938911 |
| 3 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 5.31141911 |
| 4 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 5.31141911 |
| 5 | rRNA modification (GO:0000154) | 5.30746305 |
| 6 | proteasome assembly (GO:0043248) | 5.23991322 |
| 7 | regulation of chronic inflammatory response (GO:0002676) | 5.13483125 |
| 8 | chaperone-mediated protein transport (GO:0072321) | 5.07483279 |
| 9 | DNA damage response, detection of DNA damage (GO:0042769) | 4.97692857 |
| 10 | IMP biosynthetic process (GO:0006188) | 4.30885637 |
| 11 | IMP metabolic process (GO:0046040) | 4.07523679 |
| 12 | protein neddylation (GO:0045116) | 3.92257153 |
| 13 | forebrain neuron differentiation (GO:0021879) | 3.80090168 |
| 14 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.70600843 |
| 15 | protein deneddylation (GO:0000338) | 3.69362816 |
| 16 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.67820979 |
| 17 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.65695128 |
| 18 | purine nucleobase biosynthetic process (GO:0009113) | 3.65010678 |
| 19 | cullin deneddylation (GO:0010388) | 3.64599852 |
| 20 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.59653975 |
| 21 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.59653975 |
| 22 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.59653975 |
| 23 | respiratory chain complex IV assembly (GO:0008535) | 3.59541432 |
| 24 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.58424062 |
| 25 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.54879922 |
| 26 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.54879922 |
| 27 | DNA double-strand break processing (GO:0000729) | 3.53574909 |
| 28 | peptidyl-histidine modification (GO:0018202) | 3.51607336 |
| 29 | GTP biosynthetic process (GO:0006183) | 3.51463348 |
| 30 | intracellular protein transmembrane import (GO:0044743) | 3.45392611 |
| 31 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.42733129 |
| 32 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.42733129 |
| 33 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.42266365 |
| 34 | termination of RNA polymerase I transcription (GO:0006363) | 3.40736972 |
| 35 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.38993774 |
| 36 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.35224337 |
| 37 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.33594160 |
| 38 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.33160087 |
| 39 | tRNA processing (GO:0008033) | 3.28627938 |
| 40 | ubiquinone biosynthetic process (GO:0006744) | 3.27191692 |
| 41 | spinal cord association neuron differentiation (GO:0021527) | 3.25505268 |
| 42 | maturation of 5.8S rRNA (GO:0000460) | 3.24993076 |
| 43 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.24669648 |
| 44 | nucleobase biosynthetic process (GO:0046112) | 3.23729136 |
| 45 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.22346097 |
| 46 | negative regulation of ligase activity (GO:0051352) | 3.22346097 |
| 47 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.20967458 |
| 48 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.20967458 |
| 49 | base-excision repair, AP site formation (GO:0006285) | 3.19671593 |
| 50 | ubiquinone metabolic process (GO:0006743) | 3.19206784 |
| 51 | positive regulation of humoral immune response (GO:0002922) | 3.18189676 |
| 52 | tRNA metabolic process (GO:0006399) | 3.17935934 |
| 53 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.17889661 |
| 54 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.17443375 |
| 55 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.17283240 |
| 56 | DNA deamination (GO:0045006) | 3.17152225 |
| 57 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.16854428 |
| 58 | branched-chain amino acid catabolic process (GO:0009083) | 3.14085934 |
| 59 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.12091835 |
| 60 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.07189257 |
| 61 | negative regulation of neurotransmitter secretion (GO:0046929) | 3.06271507 |
| 62 | pseudouridine synthesis (GO:0001522) | 3.05891457 |
| 63 | positive regulation of Notch signaling pathway (GO:0045747) | 3.05855775 |
| 64 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 3.05522084 |
| 65 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.03638915 |
| 66 | hypothalamus development (GO:0021854) | 2.99737603 |
| 67 | nucleotide transmembrane transport (GO:1901679) | 2.99423954 |
| 68 | negative regulation of thymocyte apoptotic process (GO:0070244) | 2.95590782 |
| 69 | replication fork processing (GO:0031297) | 2.95096449 |
| 70 | UTP biosynthetic process (GO:0006228) | 2.94240951 |
| 71 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.91354416 |
| 72 | negative regulation of neurotransmitter transport (GO:0051589) | 2.91001412 |
| 73 | transcription from RNA polymerase I promoter (GO:0006360) | 2.90767680 |
| 74 | protein complex biogenesis (GO:0070271) | 2.90485497 |
| 75 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 2.90476067 |
| 76 | lung secretory cell differentiation (GO:0061140) | 2.86992949 |
| 77 | cytochrome complex assembly (GO:0017004) | 2.83900755 |
| 78 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.83596741 |
| 79 | NADH dehydrogenase complex assembly (GO:0010257) | 2.83596741 |
| 80 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.83596741 |
| 81 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.81032713 |
| 82 | positive regulation of B cell mediated immunity (GO:0002714) | 2.80554354 |
| 83 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.80554354 |
| 84 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.80510821 |
| 85 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.78738600 |
| 86 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.78676105 |
| 87 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.78565877 |
| 88 | neuronal stem cell maintenance (GO:0097150) | 2.78047293 |
| 89 | tRNA aminoacylation (GO:0043039) | 2.77833975 |
| 90 | amino acid activation (GO:0043038) | 2.77833975 |
| 91 | cellular response to interferon-beta (GO:0035458) | 2.76637016 |
| 92 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.76487104 |
| 93 | protein targeting to mitochondrion (GO:0006626) | 2.74063341 |
| 94 | protein localization to mitochondrion (GO:0070585) | 2.73835866 |
| 95 | inner mitochondrial membrane organization (GO:0007007) | 2.72839164 |
| 96 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.71757239 |
| 97 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.70074762 |
| 98 | lymph node development (GO:0048535) | 2.69278563 |
| 99 | purine nucleotide salvage (GO:0032261) | 2.68972251 |
| 100 | positive regulation of circadian rhythm (GO:0042753) | 2.68944121 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.46371734 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.06352500 |
| 3 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.46060418 |
| 4 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.32369958 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.30616871 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.05825258 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.92734900 |
| 8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.90367913 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.90324768 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.87712982 |
| 11 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.86953367 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.80199401 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.77499636 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.61277401 |
| 15 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.53109429 |
| 16 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.46936956 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.27979661 |
| 18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.20059856 |
| 19 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.12203780 |
| 20 | EWS_26573619_Chip-Seq_HEK293_Human | 2.06938458 |
| 21 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.99025064 |
| 22 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.96404002 |
| 23 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.96122790 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.95700170 |
| 25 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.94052912 |
| 26 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.92731235 |
| 27 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.89780396 |
| 28 | FUS_26573619_Chip-Seq_HEK293_Human | 1.83073024 |
| 29 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.80153782 |
| 30 | P300_19829295_ChIP-Seq_ESCs_Human | 1.78121939 |
| 31 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.76691892 |
| 32 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.75201511 |
| 33 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.66366306 |
| 34 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.63034130 |
| 35 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.58642730 |
| 36 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.56620632 |
| 37 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.53916879 |
| 38 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.44670774 |
| 39 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.41549200 |
| 40 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.40825847 |
| 41 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.38127699 |
| 42 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.37751795 |
| 43 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.36780616 |
| 44 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.36604816 |
| 45 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.35482735 |
| 46 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.35145872 |
| 47 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.33811564 |
| 48 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.33652555 |
| 49 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.31036354 |
| 50 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.30270619 |
| 51 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.30105762 |
| 52 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.27508384 |
| 53 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.27474954 |
| 54 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.27474954 |
| 55 | GATA1_22025678_ChIP-Seq_K562_Human | 1.27350223 |
| 56 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.25817012 |
| 57 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.24454134 |
| 58 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.20583572 |
| 59 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.18189345 |
| 60 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.17943306 |
| 61 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.17943306 |
| 62 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.17291083 |
| 63 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.15850385 |
| 64 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.15762216 |
| 65 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.15207720 |
| 66 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.14312492 |
| 67 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.12947699 |
| 68 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.12450965 |
| 69 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.11770939 |
| 70 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.11770939 |
| 71 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.10670201 |
| 72 | AR_20517297_ChIP-Seq_VCAP_Human | 1.10669943 |
| 73 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.08821067 |
| 74 | NCOR_22424771_ChIP-Seq_293T_Human | 1.05482357 |
| 75 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.05464197 |
| 76 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.04244513 |
| 77 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.03442215 |
| 78 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.03177834 |
| 79 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.02406511 |
| 80 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.01409233 |
| 81 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.00610947 |
| 82 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.99508132 |
| 83 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.99008020 |
| 84 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.98772816 |
| 85 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.98037250 |
| 86 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.97085820 |
| 87 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.96433825 |
| 88 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.96130205 |
| 89 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.94676402 |
| 90 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.94361439 |
| 91 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.94335985 |
| 92 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.93614663 |
| 93 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.93177887 |
| 94 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.91609346 |
| 95 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.91488061 |
| 96 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.91053472 |
| 97 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.90558120 |
| 98 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.89080062 |
| 99 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.88360924 |
| 100 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.88289006 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001529_abnormal_vocalization | 3.07386855 |
| 2 | MP0005645_abnormal_hypothalamus_physiol | 2.82892677 |
| 3 | MP0008058_abnormal_DNA_repair | 2.72933402 |
| 4 | MP0008995_early_reproductive_senescence | 2.68612973 |
| 5 | MP0002254_reproductive_system_inflammat | 2.55342301 |
| 6 | MP0004147_increased_porphyrin_level | 2.53313368 |
| 7 | MP0003195_calcinosis | 2.52042209 |
| 8 | MP0002837_dystrophic_cardiac_calcinosis | 2.45421737 |
| 9 | MP0005167_abnormal_blood-brain_barrier | 2.33715188 |
| 10 | MP0005379_endocrine/exocrine_gland_phen | 2.32757305 |
| 11 | MP0002653_abnormal_ependyma_morphology | 2.29943800 |
| 12 | MP0008789_abnormal_olfactory_epithelium | 2.15391543 |
| 13 | MP0003718_maternal_effect | 2.03271176 |
| 14 | MP0005646_abnormal_pituitary_gland | 1.99750001 |
| 15 | MP0006292_abnormal_olfactory_placode | 1.99075290 |
| 16 | MP0008872_abnormal_physiological_respon | 1.94474532 |
| 17 | MP0000685_abnormal_immune_system | 1.88990211 |
| 18 | MP0001485_abnormal_pinna_reflex | 1.87590248 |
| 19 | MP0001348_abnormal_lacrimal_gland | 1.85696360 |
| 20 | MP0000372_irregular_coat_pigmentation | 1.81072749 |
| 21 | MP0006082_CNS_inflammation | 1.79198416 |
| 22 | MP0003693_abnormal_embryo_hatching | 1.75355981 |
| 23 | MP0003880_abnormal_central_pattern | 1.74443284 |
| 24 | MP0003786_premature_aging | 1.69857650 |
| 25 | MP0004133_heterotaxia | 1.64693992 |
| 26 | MP0009785_altered_susceptibility_to | 1.61642130 |
| 27 | MP0002736_abnormal_nociception_after | 1.56347750 |
| 28 | MP0006072_abnormal_retinal_apoptosis | 1.52728662 |
| 29 | MP0010094_abnormal_chromosome_stability | 1.51743427 |
| 30 | MP0003136_yellow_coat_color | 1.51638186 |
| 31 | MP0002102_abnormal_ear_morphology | 1.48611772 |
| 32 | MP0001873_stomach_inflammation | 1.48135547 |
| 33 | MP0003806_abnormal_nucleotide_metabolis | 1.44787707 |
| 34 | MP0009697_abnormal_copulation | 1.42847308 |
| 35 | MP0005084_abnormal_gallbladder_morpholo | 1.41601626 |
| 36 | MP0004957_abnormal_blastocyst_morpholog | 1.41580792 |
| 37 | MP0001188_hyperpigmentation | 1.40877211 |
| 38 | MP0006276_abnormal_autonomic_nervous | 1.39128787 |
| 39 | MP0005394_taste/olfaction_phenotype | 1.38242188 |
| 40 | MP0005499_abnormal_olfactory_system | 1.38242188 |
| 41 | MP0002163_abnormal_gland_morphology | 1.37917798 |
| 42 | MP0001501_abnormal_sleep_pattern | 1.37467348 |
| 43 | MP0000639_abnormal_adrenal_gland | 1.37290332 |
| 44 | MP0002751_abnormal_autonomic_nervous | 1.36863209 |
| 45 | MP0001984_abnormal_olfaction | 1.35259793 |
| 46 | MP0004019_abnormal_vitamin_homeostasis | 1.33593629 |
| 47 | MP0004084_abnormal_cardiac_muscle | 1.33521941 |
| 48 | MP0002138_abnormal_hepatobiliary_system | 1.33055532 |
| 49 | MP0008875_abnormal_xenobiotic_pharmacok | 1.31108753 |
| 50 | MP0004215_abnormal_myocardial_fiber | 1.29680959 |
| 51 | MP0004885_abnormal_endolymph | 1.26712737 |
| 52 | MP0008877_abnormal_DNA_methylation | 1.24037456 |
| 53 | MP0003252_abnormal_bile_duct | 1.23295399 |
| 54 | MP0004142_abnormal_muscle_tone | 1.21848471 |
| 55 | MP0005253_abnormal_eye_physiology | 1.20996571 |
| 56 | MP0005085_abnormal_gallbladder_physiolo | 1.20673145 |
| 57 | MP0005647_abnormal_sex_gland | 1.17557708 |
| 58 | MP0004085_abnormal_heartbeat | 1.15418991 |
| 59 | MP0005671_abnormal_response_to | 1.15013756 |
| 60 | MP0003638_abnormal_response/metabolism_ | 1.14985946 |
| 61 | MP0001905_abnormal_dopamine_level | 1.14801670 |
| 62 | MP0009764_decreased_sensitivity_to | 1.13942685 |
| 63 | MP0005551_abnormal_eye_electrophysiolog | 1.13816833 |
| 64 | MP0003878_abnormal_ear_physiology | 1.12303809 |
| 65 | MP0005377_hearing/vestibular/ear_phenot | 1.12303809 |
| 66 | MP0003137_abnormal_impulse_conducting | 1.09908927 |
| 67 | MP0003763_abnormal_thymus_physiology | 1.08016012 |
| 68 | MP0000631_abnormal_neuroendocrine_gland | 1.05880343 |
| 69 | MP0001968_abnormal_touch/_nociception | 1.02452033 |
| 70 | MP0001919_abnormal_reproductive_system | 1.01787889 |
| 71 | MP0006036_abnormal_mitochondrial_physio | 1.00296145 |
| 72 | MP0001986_abnormal_taste_sensitivity | 1.00102670 |
| 73 | MP0003119_abnormal_digestive_system | 0.98450590 |
| 74 | MP0003941_abnormal_skin_development | 0.97077765 |
| 75 | MP0006035_abnormal_mitochondrial_morpho | 0.92558291 |
| 76 | MP0000647_abnormal_sebaceous_gland | 0.90715068 |
| 77 | MP0001727_abnormal_embryo_implantation | 0.89001987 |
| 78 | MP0009384_cardiac_valve_regurgitation | 0.88751886 |
| 79 | MP0003011_delayed_dark_adaptation | 0.88539092 |
| 80 | MP0001764_abnormal_homeostasis | 0.87232027 |
| 81 | MP0006054_spinal_hemorrhage | 0.87018419 |
| 82 | MP0002234_abnormal_pharynx_morphology | 0.86605191 |
| 83 | MP0005165_increased_susceptibility_to | 0.86546080 |
| 84 | MP0001293_anophthalmia | 0.84210568 |
| 85 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.82179826 |
| 86 | MP0002210_abnormal_sex_determination | 0.81613936 |
| 87 | MP0003937_abnormal_limbs/digits/tail_de | 0.79595531 |
| 88 | MP0002166_altered_tumor_susceptibility | 0.77767998 |
| 89 | MP0005083_abnormal_biliary_tract | 0.77463968 |
| 90 | MP0002160_abnormal_reproductive_system | 0.76435906 |
| 91 | MP0002938_white_spotting | 0.75859798 |
| 92 | MP0005389_reproductive_system_phenotype | 0.75733022 |
| 93 | MP0003186_abnormal_redox_activity | 0.75614506 |
| 94 | MP0004381_abnormal_hair_follicle | 0.74991243 |
| 95 | MP0001835_abnormal_antigen_presentation | 0.74726557 |
| 96 | MP0001286_abnormal_eye_development | 0.74183617 |
| 97 | MP0005310_abnormal_salivary_gland | 0.70444758 |
| 98 | MP0002006_tumorigenesis | 0.69975448 |
| 99 | MP0005408_hypopigmentation | 0.69269147 |
| 100 | MP0000026_abnormal_inner_ear | 0.69209249 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute encephalopathy (HP:0006846) | 4.32110777 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.18801382 |
| 3 | Thyroid-stimulating hormone excess (HP:0002925) | 4.17240302 |
| 4 | Hepatocellular necrosis (HP:0001404) | 3.87279315 |
| 5 | 3-Methylglutaconic aciduria (HP:0003535) | 3.82238092 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.56267796 |
| 7 | Delayed CNS myelination (HP:0002188) | 3.46780358 |
| 8 | Lipid accumulation in hepatocytes (HP:0006561) | 3.38970946 |
| 9 | Increased CSF lactate (HP:0002490) | 3.34697298 |
| 10 | Progressive macrocephaly (HP:0004481) | 3.34118381 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.32547035 |
| 12 | Aplasia/hypoplasia of the uterus (HP:0008684) | 3.30309638 |
| 13 | Mitochondrial inheritance (HP:0001427) | 3.29207377 |
| 14 | Hyperglycinemia (HP:0002154) | 3.08225958 |
| 15 | Increased serum pyruvate (HP:0003542) | 3.03876908 |
| 16 | Hepatic necrosis (HP:0002605) | 3.00226776 |
| 17 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.96429120 |
| 18 | Abnormality of alanine metabolism (HP:0010916) | 2.96429120 |
| 19 | Hyperalaninemia (HP:0003348) | 2.96429120 |
| 20 | Methylmalonic aciduria (HP:0012120) | 2.93543963 |
| 21 | Cerebral edema (HP:0002181) | 2.92531786 |
| 22 | Pancreatic cysts (HP:0001737) | 2.87326579 |
| 23 | Hypoplasia of the uterus (HP:0000013) | 2.86456554 |
| 24 | Sensorimotor neuropathy (HP:0007141) | 2.83905123 |
| 25 | Increased serum lactate (HP:0002151) | 2.83394171 |
| 26 | Methylmalonic acidemia (HP:0002912) | 2.78219805 |
| 27 | Nephronophthisis (HP:0000090) | 2.65350188 |
| 28 | Abnormality of serum amino acid levels (HP:0003112) | 2.55255766 |
| 29 | Abnormality of the renal medulla (HP:0100957) | 2.53422762 |
| 30 | Abnormality of glycolysis (HP:0004366) | 2.49012489 |
| 31 | Fibular aplasia (HP:0002990) | 2.46910082 |
| 32 | Lactic acidosis (HP:0003128) | 2.43830292 |
| 33 | Neonatal respiratory distress (HP:0002643) | 2.43310045 |
| 34 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 2.42401034 |
| 35 | B lymphocytopenia (HP:0010976) | 2.39552358 |
| 36 | Medial flaring of the eyebrow (HP:0010747) | 2.38515450 |
| 37 | Prominent metopic ridge (HP:0005487) | 2.38116119 |
| 38 | Opisthotonus (HP:0002179) | 2.32797430 |
| 39 | Limb hypertonia (HP:0002509) | 2.32052718 |
| 40 | Metabolic alkalosis (HP:0200114) | 2.31307187 |
| 41 | Hypoproteinemia (HP:0003075) | 2.29771483 |
| 42 | Abnormality of glycine metabolism (HP:0010895) | 2.29099964 |
| 43 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.29099964 |
| 44 | Meckel diverticulum (HP:0002245) | 2.26390769 |
| 45 | Abnormality of the ileum (HP:0001549) | 2.24253374 |
| 46 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.24246191 |
| 47 | Congenital, generalized hypertrichosis (HP:0004540) | 2.23425517 |
| 48 | Microvesicular hepatic steatosis (HP:0001414) | 2.23421522 |
| 49 | Cerebellar dysplasia (HP:0007033) | 2.22071057 |
| 50 | Type II lissencephaly (HP:0007260) | 2.21936554 |
| 51 | Optic disc pallor (HP:0000543) | 2.21132811 |
| 52 | Severe combined immunodeficiency (HP:0004430) | 2.21043102 |
| 53 | Abnormality of the metopic suture (HP:0005556) | 2.20762561 |
| 54 | Renal Fanconi syndrome (HP:0001994) | 2.20683957 |
| 55 | CNS demyelination (HP:0007305) | 2.17352478 |
| 56 | Abnormality of the renal cortex (HP:0011035) | 2.13230075 |
| 57 | True hermaphroditism (HP:0010459) | 2.10639382 |
| 58 | Carpal bone hypoplasia (HP:0001498) | 2.09762011 |
| 59 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.09403616 |
| 60 | Inability to walk (HP:0002540) | 2.08965284 |
| 61 | Abnormality of B cell number (HP:0010975) | 2.06441225 |
| 62 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.03447457 |
| 63 | Hyperglycinuria (HP:0003108) | 2.03040948 |
| 64 | Hypokalemic alkalosis (HP:0001949) | 2.01663760 |
| 65 | Thyroiditis (HP:0100646) | 2.00761821 |
| 66 | Abnormality of vitamin B metabolism (HP:0004340) | 1.99763053 |
| 67 | IgG deficiency (HP:0004315) | 1.99011709 |
| 68 | Lethargy (HP:0001254) | 1.98522782 |
| 69 | Stomatitis (HP:0010280) | 1.98113204 |
| 70 | Colon cancer (HP:0003003) | 1.97196633 |
| 71 | Thoracolumbar scoliosis (HP:0002944) | 1.96193908 |
| 72 | Abnormality of midbrain morphology (HP:0002418) | 1.95751624 |
| 73 | Molar tooth sign on MRI (HP:0002419) | 1.95751624 |
| 74 | Abnormality of the fovea (HP:0000493) | 1.93884475 |
| 75 | Abnormality of methionine metabolism (HP:0010901) | 1.92721635 |
| 76 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.86277158 |
| 77 | Hypoplasia of the pons (HP:0012110) | 1.85223679 |
| 78 | Respiratory failure (HP:0002878) | 1.84612454 |
| 79 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.83396299 |
| 80 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.83361480 |
| 81 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.83357585 |
| 82 | Submucous cleft hard palate (HP:0000176) | 1.82145095 |
| 83 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.82042302 |
| 84 | Chorioretinal atrophy (HP:0000533) | 1.81619923 |
| 85 | Neuroblastic tumors (HP:0004376) | 1.81103942 |
| 86 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 1.81103942 |
| 87 | Neuroblastoma (HP:0003006) | 1.81103942 |
| 88 | Primitive neuroectodermal tumor (HP:0030065) | 1.81103942 |
| 89 | Choreoathetosis (HP:0001266) | 1.80431360 |
| 90 | Hypoplasia of the ulna (HP:0003022) | 1.79451981 |
| 91 | Abnormality of the pons (HP:0007361) | 1.76881261 |
| 92 | Poor suck (HP:0002033) | 1.75689649 |
| 93 | Abnormality of chromosome stability (HP:0003220) | 1.74740863 |
| 94 | Progressive microcephaly (HP:0000253) | 1.74145863 |
| 95 | Leukodystrophy (HP:0002415) | 1.71996276 |
| 96 | Polyuria (HP:0000103) | 1.71591768 |
| 97 | Congenital sensorineural hearing impairment (HP:0008527) | 1.71442812 |
| 98 | Tubulointerstitial nephritis (HP:0001970) | 1.71087714 |
| 99 | Combined immunodeficiency (HP:0005387) | 1.71073829 |
| 100 | Exertional dyspnea (HP:0002875) | 1.70488819 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 6.94171239 |
| 2 | TRIM28 | 5.24540825 |
| 3 | TSSK6 | 4.73462559 |
| 4 | SRPK1 | 3.43227771 |
| 5 | BCKDK | 2.96517663 |
| 6 | MST4 | 2.48815108 |
| 7 | AKT3 | 2.47236883 |
| 8 | SIK3 | 2.20069309 |
| 9 | EIF2AK3 | 2.09149355 |
| 10 | MKNK1 | 1.96336937 |
| 11 | NEK1 | 1.90722997 |
| 12 | TXK | 1.88492006 |
| 13 | ZAK | 1.84577658 |
| 14 | CSNK1G3 | 1.81102037 |
| 15 | CSNK1G1 | 1.69137653 |
| 16 | PASK | 1.62136947 |
| 17 | BCR | 1.62078819 |
| 18 | CSNK1G2 | 1.50264541 |
| 19 | CSNK1A1L | 1.49320749 |
| 20 | NUAK1 | 1.42312022 |
| 21 | EIF2AK1 | 1.39119942 |
| 22 | PLK3 | 1.36841789 |
| 23 | VRK2 | 1.36474345 |
| 24 | PBK | 1.31741257 |
| 25 | TGFBR1 | 1.30227748 |
| 26 | WNK3 | 1.28482161 |
| 27 | NME1 | 1.24274939 |
| 28 | MKNK2 | 1.24268797 |
| 29 | EIF2AK2 | 1.21358240 |
| 30 | MAP3K4 | 1.13890541 |
| 31 | ADRBK2 | 1.12419394 |
| 32 | GRK1 | 1.11596247 |
| 33 | TAF1 | 1.10584001 |
| 34 | WNK4 | 1.09834672 |
| 35 | TLK1 | 1.07021924 |
| 36 | TEC | 1.06417231 |
| 37 | OXSR1 | 1.03267169 |
| 38 | BMPR1B | 1.01528218 |
| 39 | KIT | 0.98914107 |
| 40 | CDK19 | 0.98286002 |
| 41 | EPHA3 | 0.97089306 |
| 42 | PLK4 | 0.96784549 |
| 43 | IKBKE | 0.93391450 |
| 44 | STK39 | 0.92698567 |
| 45 | CDC7 | 0.91819280 |
| 46 | MAP3K12 | 0.80095772 |
| 47 | GRK6 | 0.69931646 |
| 48 | VRK1 | 0.68824026 |
| 49 | FRK | 0.67713166 |
| 50 | MAPKAPK3 | 0.66354771 |
| 51 | JAK3 | 0.66271925 |
| 52 | PLK2 | 0.66027404 |
| 53 | PIK3CA | 0.65833420 |
| 54 | TAOK3 | 0.62011721 |
| 55 | ACVR1B | 0.59468242 |
| 56 | FGFR4 | 0.58063840 |
| 57 | TNIK | 0.57276213 |
| 58 | RIPK4 | 0.55383623 |
| 59 | TYK2 | 0.54062506 |
| 60 | TIE1 | 0.52523172 |
| 61 | ITK | 0.52109267 |
| 62 | FER | 0.50387315 |
| 63 | ALK | 0.49321587 |
| 64 | ATR | 0.49189882 |
| 65 | PRKCG | 0.47004422 |
| 66 | NLK | 0.46967736 |
| 67 | PLK1 | 0.45554648 |
| 68 | CSNK1A1 | 0.43984608 |
| 69 | RPS6KA4 | 0.42734952 |
| 70 | BRAF | 0.42651054 |
| 71 | CSNK2A1 | 0.41162030 |
| 72 | EPHA4 | 0.40070095 |
| 73 | PRKG1 | 0.39035345 |
| 74 | DAPK1 | 0.36226306 |
| 75 | CSNK2A2 | 0.35489330 |
| 76 | RPS6KA5 | 0.32957998 |
| 77 | CSNK1E | 0.32932473 |
| 78 | PINK1 | 0.32252851 |
| 79 | INSRR | 0.32144350 |
| 80 | STK3 | 0.30726134 |
| 81 | PRKCE | 0.30696126 |
| 82 | ATM | 0.29526875 |
| 83 | OBSCN | 0.29442121 |
| 84 | MAP3K11 | 0.28600506 |
| 85 | EGFR | 0.28079779 |
| 86 | PRKG2 | 0.27423295 |
| 87 | CCNB1 | 0.27031123 |
| 88 | CAMK2A | 0.26195706 |
| 89 | CAMK1 | 0.25706147 |
| 90 | DYRK2 | 0.25519867 |
| 91 | MAP2K7 | 0.25385050 |
| 92 | MAP2K6 | 0.25027547 |
| 93 | CSNK1D | 0.24600230 |
| 94 | TTK | 0.24520547 |
| 95 | STK38L | 0.23924825 |
| 96 | AURKB | 0.22044829 |
| 97 | BTK | 0.21917765 |
| 98 | IKBKB | 0.21521066 |
| 99 | ADRBK1 | 0.20509993 |
| 100 | FGFR1 | 0.20296656 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.92113444 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.06543096 |
| 3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.80859742 |
| 4 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.69147847 |
| 5 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.53993465 |
| 6 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.51504891 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.28371782 |
| 8 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.23448885 |
| 9 | Basal transcription factors_Homo sapiens_hsa03022 | 2.22571778 |
| 10 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.20017895 |
| 11 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.05879197 |
| 12 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.04264861 |
| 13 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.99853181 |
| 14 | RNA degradation_Homo sapiens_hsa03018 | 1.97769864 |
| 15 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.96845855 |
| 16 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.94962401 |
| 17 | Ribosome_Homo sapiens_hsa03010 | 1.89462316 |
| 18 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.88304500 |
| 19 | Phototransduction_Homo sapiens_hsa04744 | 1.76258776 |
| 20 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.75237663 |
| 21 | Parkinsons disease_Homo sapiens_hsa05012 | 1.75145812 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.73429716 |
| 23 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.72838184 |
| 24 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.70522870 |
| 25 | Spliceosome_Homo sapiens_hsa03040 | 1.67986655 |
| 26 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.53112484 |
| 27 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.50743634 |
| 28 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.49838087 |
| 29 | Homologous recombination_Homo sapiens_hsa03440 | 1.45117427 |
| 30 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.42271902 |
| 31 | Mismatch repair_Homo sapiens_hsa03430 | 1.40667941 |
| 32 | RNA transport_Homo sapiens_hsa03013 | 1.32772164 |
| 33 | Huntingtons disease_Homo sapiens_hsa05016 | 1.28236716 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.26619032 |
| 35 | Purine metabolism_Homo sapiens_hsa00230 | 1.24042518 |
| 36 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.22692577 |
| 37 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.19230162 |
| 38 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.15920572 |
| 39 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.14974529 |
| 40 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.09001690 |
| 41 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.08031222 |
| 42 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.07554448 |
| 43 | Base excision repair_Homo sapiens_hsa03410 | 1.05390791 |
| 44 | Peroxisome_Homo sapiens_hsa04146 | 1.02015407 |
| 45 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.99056585 |
| 46 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.96583960 |
| 47 | Alzheimers disease_Homo sapiens_hsa05010 | 0.94050520 |
| 48 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.93983552 |
| 49 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.93621089 |
| 50 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.90737173 |
| 51 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.84837545 |
| 52 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.83758083 |
| 53 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.78240750 |
| 54 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.76976171 |
| 55 | Asthma_Homo sapiens_hsa05310 | 0.76162647 |
| 56 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.74367491 |
| 57 | Metabolic pathways_Homo sapiens_hsa01100 | 0.73580546 |
| 58 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.73013994 |
| 59 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.72829958 |
| 60 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.69390423 |
| 61 | Retinol metabolism_Homo sapiens_hsa00830 | 0.68573766 |
| 62 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.66916819 |
| 63 | Circadian rhythm_Homo sapiens_hsa04710 | 0.66800166 |
| 64 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.64510593 |
| 65 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.64307880 |
| 66 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.63483634 |
| 67 | ABC transporters_Homo sapiens_hsa02010 | 0.62452304 |
| 68 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.62141832 |
| 69 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.59578021 |
| 70 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.58034138 |
| 71 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.57302086 |
| 72 | Nicotine addiction_Homo sapiens_hsa05033 | 0.55784074 |
| 73 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.50568287 |
| 74 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.50173011 |
| 75 | DNA replication_Homo sapiens_hsa03030 | 0.49996283 |
| 76 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.45437364 |
| 77 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.44455220 |
| 78 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44137852 |
| 79 | Carbon metabolism_Homo sapiens_hsa01200 | 0.43872236 |
| 80 | Morphine addiction_Homo sapiens_hsa05032 | 0.42314662 |
| 81 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.40187120 |
| 82 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.39254799 |
| 83 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.39143510 |
| 84 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.38444551 |
| 85 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.36977232 |
| 86 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.36364515 |
| 87 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.36261071 |
| 88 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.33963707 |
| 89 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.32789433 |
| 90 | Olfactory transduction_Homo sapiens_hsa04740 | 0.32780156 |
| 91 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.31224629 |
| 92 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.31187025 |
| 93 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.30830322 |
| 94 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.30310428 |
| 95 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.30294800 |
| 96 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.29129741 |
| 97 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.25670768 |
| 98 | GABAergic synapse_Homo sapiens_hsa04727 | 0.24538117 |
| 99 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.24272695 |
| 100 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.22315363 |

