HNRNPDLP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1establishment of protein localization to mitochondrial membrane (GO:0090151)5.42932636
2rRNA methylation (GO:0031167)5.31938911
3tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)5.31141911
4RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)5.31141911
5rRNA modification (GO:0000154)5.30746305
6proteasome assembly (GO:0043248)5.23991322
7regulation of chronic inflammatory response (GO:0002676)5.13483125
8chaperone-mediated protein transport (GO:0072321)5.07483279
9DNA damage response, detection of DNA damage (GO:0042769)4.97692857
10IMP biosynthetic process (GO:0006188)4.30885637
11IMP metabolic process (GO:0046040)4.07523679
12protein neddylation (GO:0045116)3.92257153
13forebrain neuron differentiation (GO:0021879)3.80090168
14transcription elongation from RNA polymerase I promoter (GO:0006362)3.70600843
15protein deneddylation (GO:0000338)3.69362816
16negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.67820979
17DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.65695128
18purine nucleobase biosynthetic process (GO:0009113)3.65010678
19cullin deneddylation (GO:0010388)3.64599852
20signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.59653975
21signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.59653975
22signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.59653975
23respiratory chain complex IV assembly (GO:0008535)3.59541432
24regulation of cellular amino acid metabolic process (GO:0006521)3.58424062
25signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.54879922
26intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.54879922
27DNA double-strand break processing (GO:0000729)3.53574909
28peptidyl-histidine modification (GO:0018202)3.51607336
29GTP biosynthetic process (GO:0006183)3.51463348
30intracellular protein transmembrane import (GO:0044743)3.45392611
31signal transduction involved in DNA integrity checkpoint (GO:0072401)3.42733129
32signal transduction involved in DNA damage checkpoint (GO:0072422)3.42733129
33signal transduction involved in cell cycle checkpoint (GO:0072395)3.42266365
34termination of RNA polymerase I transcription (GO:0006363)3.40736972
35water-soluble vitamin biosynthetic process (GO:0042364)3.38993774
36positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.35224337
37exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.33594160
38regulation of T-helper 1 cell differentiation (GO:0045625)3.33160087
39tRNA processing (GO:0008033)3.28627938
40ubiquinone biosynthetic process (GO:0006744)3.27191692
41spinal cord association neuron differentiation (GO:0021527)3.25505268
42maturation of 5.8S rRNA (GO:0000460)3.24993076
43positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.24669648
44nucleobase biosynthetic process (GO:0046112)3.23729136
45negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.22346097
46negative regulation of ligase activity (GO:0051352)3.22346097
47negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.20967458
48negative regulation of T-helper cell differentiation (GO:0045623)3.20967458
49base-excision repair, AP site formation (GO:0006285)3.19671593
50ubiquinone metabolic process (GO:0006743)3.19206784
51positive regulation of humoral immune response (GO:0002922)3.18189676
52tRNA metabolic process (GO:0006399)3.17935934
53positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.17889661
54DNA catabolic process, exonucleolytic (GO:0000738)3.17443375
55nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.17283240
56DNA deamination (GO:0045006)3.17152225
57regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.16854428
58branched-chain amino acid catabolic process (GO:0009083)3.14085934
59transcription initiation from RNA polymerase I promoter (GO:0006361)3.12091835
60negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)3.07189257
61negative regulation of neurotransmitter secretion (GO:0046929)3.06271507
62pseudouridine synthesis (GO:0001522)3.05891457
63positive regulation of Notch signaling pathway (GO:0045747)3.05855775
64negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.05522084
65pteridine-containing compound biosynthetic process (GO:0042559)3.03638915
66hypothalamus development (GO:0021854)2.99737603
67nucleotide transmembrane transport (GO:1901679)2.99423954
68negative regulation of thymocyte apoptotic process (GO:0070244)2.95590782
69replication fork processing (GO:0031297)2.95096449
70UTP biosynthetic process (GO:0006228)2.94240951
71regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.91354416
72negative regulation of neurotransmitter transport (GO:0051589)2.91001412
73transcription from RNA polymerase I promoter (GO:0006360)2.90767680
74protein complex biogenesis (GO:0070271)2.90485497
75negative regulation of alpha-beta T cell differentiation (GO:0046639)2.90476067
76lung secretory cell differentiation (GO:0061140)2.86992949
77cytochrome complex assembly (GO:0017004)2.83900755
78mitochondrial respiratory chain complex I assembly (GO:0032981)2.83596741
79NADH dehydrogenase complex assembly (GO:0010257)2.83596741
80mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.83596741
81mitochondrial respiratory chain complex assembly (GO:0033108)2.81032713
82positive regulation of B cell mediated immunity (GO:0002714)2.80554354
83positive regulation of immunoglobulin mediated immune response (GO:0002891)2.80554354
84folic acid-containing compound biosynthetic process (GO:0009396)2.80510821
85DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.78738600
86regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.78676105
87anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.78565877
88neuronal stem cell maintenance (GO:0097150)2.78047293
89tRNA aminoacylation (GO:0043039)2.77833975
90amino acid activation (GO:0043038)2.77833975
91cellular response to interferon-beta (GO:0035458)2.76637016
92positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.76487104
93protein targeting to mitochondrion (GO:0006626)2.74063341
94protein localization to mitochondrion (GO:0070585)2.73835866
95inner mitochondrial membrane organization (GO:0007007)2.72839164
96negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.71757239
97antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.70074762
98lymph node development (GO:0048535)2.69278563
99purine nucleotide salvage (GO:0032261)2.68972251
100positive regulation of circadian rhythm (GO:0042753)2.68944121

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GABP_17652178_ChIP-ChIP_JURKAT_Human4.46371734
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.06352500
3IGF1R_20145208_ChIP-Seq_DFB_Human3.46060418
4HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.32369958
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.30616871
6ELF1_17652178_ChIP-ChIP_JURKAT_Human3.05825258
7ZNF274_21170338_ChIP-Seq_K562_Hela2.92734900
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.90367913
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.90324768
10VDR_22108803_ChIP-Seq_LS180_Human2.87712982
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.86953367
12VDR_23849224_ChIP-Seq_CD4+_Human2.80199401
13SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.77499636
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.61277401
15FLI1_27457419_Chip-Seq_LIVER_Mouse2.53109429
16CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.46936956
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.27979661
18ELK1_19687146_ChIP-ChIP_HELA_Human2.20059856
19TAF15_26573619_Chip-Seq_HEK293_Human2.12203780
20EWS_26573619_Chip-Seq_HEK293_Human2.06938458
21MYC_18555785_ChIP-Seq_MESCs_Mouse1.99025064
22NOTCH1_21737748_ChIP-Seq_TLL_Human1.96404002
23PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.96122790
24FOXP3_21729870_ChIP-Seq_TREG_Human1.95700170
25PCGF2_27294783_Chip-Seq_ESCs_Mouse1.94052912
26CREB1_15753290_ChIP-ChIP_HEK293T_Human1.92731235
27FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.89780396
28FUS_26573619_Chip-Seq_HEK293_Human1.83073024
29SRF_21415370_ChIP-Seq_HL-1_Mouse1.80153782
30P300_19829295_ChIP-Seq_ESCs_Human1.78121939
31ER_23166858_ChIP-Seq_MCF-7_Human1.76691892
32PADI4_21655091_ChIP-ChIP_MCF-7_Human1.75201511
33POU3F2_20337985_ChIP-ChIP_501MEL_Human1.66366306
34MYC_18940864_ChIP-ChIP_HL60_Human1.63034130
35SUZ12_27294783_Chip-Seq_NPCs_Mouse1.58642730
36GABP_19822575_ChIP-Seq_HepG2_Human1.56620632
37MYC_19030024_ChIP-ChIP_MESCs_Mouse1.53916879
38MYC_18358816_ChIP-ChIP_MESCs_Mouse1.44670774
39DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.41549200
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.40825847
41PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.38127699
42ZFP57_27257070_Chip-Seq_ESCs_Mouse1.37751795
43EZH2_27294783_Chip-Seq_NPCs_Mouse1.36780616
44IRF1_19129219_ChIP-ChIP_H3396_Human1.36604816
45TP53_22573176_ChIP-Seq_HFKS_Human1.35482735
46DCP1A_22483619_ChIP-Seq_HELA_Human1.35145872
47NFE2_27457419_Chip-Seq_LIVER_Mouse1.33811564
48PCGF2_27294783_Chip-Seq_NPCs_Mouse1.33652555
49CTBP1_25329375_ChIP-Seq_LNCAP_Human1.31036354
50YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.30270619
51GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30105762
52CTBP2_25329375_ChIP-Seq_LNCAP_Human1.27508384
53IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.27474954
54CBP_20019798_ChIP-Seq_JUKART_Human1.27474954
55GATA1_22025678_ChIP-Seq_K562_Human1.27350223
56CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.25817012
57EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.24454134
58YY1_21170310_ChIP-Seq_MESCs_Mouse1.20583572
59E2F4_17652178_ChIP-ChIP_JURKAT_Human1.18189345
60FOXA1_27270436_Chip-Seq_PROSTATE_Human1.17943306
61FOXA1_25329375_ChIP-Seq_VCAP_Human1.17943306
62KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17291083
63E2F1_18555785_ChIP-Seq_MESCs_Mouse1.15850385
64CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.15762216
65TTF2_22483619_ChIP-Seq_HELA_Human1.15207720
66MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.14312492
67ELK1_22589737_ChIP-Seq_MCF10A_Human1.12947699
68MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.12450965
69NANOG_19829295_ChIP-Seq_ESCs_Human1.11770939
70SOX2_19829295_ChIP-Seq_ESCs_Human1.11770939
71HOXB4_20404135_ChIP-ChIP_EML_Mouse1.10670201
72AR_20517297_ChIP-Seq_VCAP_Human1.10669943
73GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.08821067
74NCOR_22424771_ChIP-Seq_293T_Human1.05482357
75CRX_20693478_ChIP-Seq_RETINA_Mouse1.05464197
76HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.04244513
77CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.03442215
78POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.03177834
79THAP11_20581084_ChIP-Seq_MESCs_Mouse1.02406511
80HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.01409233
81ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.00610947
82FOXA1_21572438_ChIP-Seq_LNCaP_Human0.99508132
83FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.99008020
84ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.98772816
85P53_22387025_ChIP-Seq_ESCs_Mouse0.98037250
86MYC_19079543_ChIP-ChIP_MESCs_Mouse0.97085820
87HOXB7_26014856_ChIP-Seq_BT474_Human0.96433825
88FOXH1_21741376_ChIP-Seq_EPCs_Human0.96130205
89NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.94676402
90CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.94361439
91ELF5_23300383_ChIP-Seq_T47D_Human0.94335985
92NELFA_20434984_ChIP-Seq_ESCs_Mouse0.93614663
93ETV2_25802403_ChIP-Seq_MESCs_Mouse0.93177887
94SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.91609346
95RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.91488061
96LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.91053472
97POU5F1_16153702_ChIP-ChIP_HESCs_Human0.90558120
98GBX2_23144817_ChIP-Seq_PC3_Human0.89080062
99RBPJ_21746931_ChIP-Seq_IB4_Human0.88360924
100TCF4_22108803_ChIP-Seq_LS180_Human0.88289006

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001529_abnormal_vocalization3.07386855
2MP0005645_abnormal_hypothalamus_physiol2.82892677
3MP0008058_abnormal_DNA_repair2.72933402
4MP0008995_early_reproductive_senescence2.68612973
5MP0002254_reproductive_system_inflammat2.55342301
6MP0004147_increased_porphyrin_level2.53313368
7MP0003195_calcinosis2.52042209
8MP0002837_dystrophic_cardiac_calcinosis2.45421737
9MP0005167_abnormal_blood-brain_barrier2.33715188
10MP0005379_endocrine/exocrine_gland_phen2.32757305
11MP0002653_abnormal_ependyma_morphology2.29943800
12MP0008789_abnormal_olfactory_epithelium2.15391543
13MP0003718_maternal_effect2.03271176
14MP0005646_abnormal_pituitary_gland1.99750001
15MP0006292_abnormal_olfactory_placode1.99075290
16MP0008872_abnormal_physiological_respon1.94474532
17MP0000685_abnormal_immune_system1.88990211
18MP0001485_abnormal_pinna_reflex1.87590248
19MP0001348_abnormal_lacrimal_gland1.85696360
20MP0000372_irregular_coat_pigmentation1.81072749
21MP0006082_CNS_inflammation1.79198416
22MP0003693_abnormal_embryo_hatching1.75355981
23MP0003880_abnormal_central_pattern1.74443284
24MP0003786_premature_aging1.69857650
25MP0004133_heterotaxia1.64693992
26MP0009785_altered_susceptibility_to1.61642130
27MP0002736_abnormal_nociception_after1.56347750
28MP0006072_abnormal_retinal_apoptosis1.52728662
29MP0010094_abnormal_chromosome_stability1.51743427
30MP0003136_yellow_coat_color1.51638186
31MP0002102_abnormal_ear_morphology1.48611772
32MP0001873_stomach_inflammation1.48135547
33MP0003806_abnormal_nucleotide_metabolis1.44787707
34MP0009697_abnormal_copulation1.42847308
35MP0005084_abnormal_gallbladder_morpholo1.41601626
36MP0004957_abnormal_blastocyst_morpholog1.41580792
37MP0001188_hyperpigmentation1.40877211
38MP0006276_abnormal_autonomic_nervous1.39128787
39MP0005394_taste/olfaction_phenotype1.38242188
40MP0005499_abnormal_olfactory_system1.38242188
41MP0002163_abnormal_gland_morphology1.37917798
42MP0001501_abnormal_sleep_pattern1.37467348
43MP0000639_abnormal_adrenal_gland1.37290332
44MP0002751_abnormal_autonomic_nervous1.36863209
45MP0001984_abnormal_olfaction1.35259793
46MP0004019_abnormal_vitamin_homeostasis1.33593629
47MP0004084_abnormal_cardiac_muscle1.33521941
48MP0002138_abnormal_hepatobiliary_system1.33055532
49MP0008875_abnormal_xenobiotic_pharmacok1.31108753
50MP0004215_abnormal_myocardial_fiber1.29680959
51MP0004885_abnormal_endolymph1.26712737
52MP0008877_abnormal_DNA_methylation1.24037456
53MP0003252_abnormal_bile_duct1.23295399
54MP0004142_abnormal_muscle_tone1.21848471
55MP0005253_abnormal_eye_physiology1.20996571
56MP0005085_abnormal_gallbladder_physiolo1.20673145
57MP0005647_abnormal_sex_gland1.17557708
58MP0004085_abnormal_heartbeat1.15418991
59MP0005671_abnormal_response_to1.15013756
60MP0003638_abnormal_response/metabolism_1.14985946
61MP0001905_abnormal_dopamine_level1.14801670
62MP0009764_decreased_sensitivity_to1.13942685
63MP0005551_abnormal_eye_electrophysiolog1.13816833
64MP0003878_abnormal_ear_physiology1.12303809
65MP0005377_hearing/vestibular/ear_phenot1.12303809
66MP0003137_abnormal_impulse_conducting1.09908927
67MP0003763_abnormal_thymus_physiology1.08016012
68MP0000631_abnormal_neuroendocrine_gland1.05880343
69MP0001968_abnormal_touch/_nociception1.02452033
70MP0001919_abnormal_reproductive_system1.01787889
71MP0006036_abnormal_mitochondrial_physio1.00296145
72MP0001986_abnormal_taste_sensitivity1.00102670
73MP0003119_abnormal_digestive_system0.98450590
74MP0003941_abnormal_skin_development0.97077765
75MP0006035_abnormal_mitochondrial_morpho0.92558291
76MP0000647_abnormal_sebaceous_gland0.90715068
77MP0001727_abnormal_embryo_implantation0.89001987
78MP0009384_cardiac_valve_regurgitation0.88751886
79MP0003011_delayed_dark_adaptation0.88539092
80MP0001764_abnormal_homeostasis0.87232027
81MP0006054_spinal_hemorrhage0.87018419
82MP0002234_abnormal_pharynx_morphology0.86605191
83MP0005165_increased_susceptibility_to0.86546080
84MP0001293_anophthalmia0.84210568
85MP0005584_abnormal_enzyme/coenzyme_acti0.82179826
86MP0002210_abnormal_sex_determination0.81613936
87MP0003937_abnormal_limbs/digits/tail_de0.79595531
88MP0002166_altered_tumor_susceptibility0.77767998
89MP0005083_abnormal_biliary_tract0.77463968
90MP0002160_abnormal_reproductive_system0.76435906
91MP0002938_white_spotting0.75859798
92MP0005389_reproductive_system_phenotype0.75733022
93MP0003186_abnormal_redox_activity0.75614506
94MP0004381_abnormal_hair_follicle0.74991243
95MP0001835_abnormal_antigen_presentation0.74726557
96MP0001286_abnormal_eye_development0.74183617
97MP0005310_abnormal_salivary_gland0.70444758
98MP0002006_tumorigenesis0.69975448
99MP0005408_hypopigmentation0.69269147
100MP0000026_abnormal_inner_ear0.69209249

Predicted human phenotypes

RankGene SetZ-score
1Acute encephalopathy (HP:0006846)4.32110777
2Acute necrotizing encephalopathy (HP:0006965)4.18801382
3Thyroid-stimulating hormone excess (HP:0002925)4.17240302
4Hepatocellular necrosis (HP:0001404)3.87279315
53-Methylglutaconic aciduria (HP:0003535)3.82238092
6Abnormal mitochondria in muscle tissue (HP:0008316)3.56267796
7Delayed CNS myelination (HP:0002188)3.46780358
8Lipid accumulation in hepatocytes (HP:0006561)3.38970946
9Increased CSF lactate (HP:0002490)3.34697298
10Progressive macrocephaly (HP:0004481)3.34118381
11Increased hepatocellular lipid droplets (HP:0006565)3.32547035
12Aplasia/hypoplasia of the uterus (HP:0008684)3.30309638
13Mitochondrial inheritance (HP:0001427)3.29207377
14Hyperglycinemia (HP:0002154)3.08225958
15Increased serum pyruvate (HP:0003542)3.03876908
16Hepatic necrosis (HP:0002605)3.00226776
17Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.96429120
18Abnormality of alanine metabolism (HP:0010916)2.96429120
19Hyperalaninemia (HP:0003348)2.96429120
20Methylmalonic aciduria (HP:0012120)2.93543963
21Cerebral edema (HP:0002181)2.92531786
22Pancreatic cysts (HP:0001737)2.87326579
23Hypoplasia of the uterus (HP:0000013)2.86456554
24Sensorimotor neuropathy (HP:0007141)2.83905123
25Increased serum lactate (HP:0002151)2.83394171
26Methylmalonic acidemia (HP:0002912)2.78219805
27Nephronophthisis (HP:0000090)2.65350188
28Abnormality of serum amino acid levels (HP:0003112)2.55255766
29Abnormality of the renal medulla (HP:0100957)2.53422762
30Abnormality of glycolysis (HP:0004366)2.49012489
31Fibular aplasia (HP:0002990)2.46910082
32Lactic acidosis (HP:0003128)2.43830292
33Neonatal respiratory distress (HP:0002643)2.43310045
34Aplasia/Hypoplasia involving the musculature (HP:0001460)2.42401034
35B lymphocytopenia (HP:0010976)2.39552358
36Medial flaring of the eyebrow (HP:0010747)2.38515450
37Prominent metopic ridge (HP:0005487)2.38116119
38Opisthotonus (HP:0002179)2.32797430
39Limb hypertonia (HP:0002509)2.32052718
40Metabolic alkalosis (HP:0200114)2.31307187
41Hypoproteinemia (HP:0003075)2.29771483
42Abnormality of glycine metabolism (HP:0010895)2.29099964
43Abnormality of serine family amino acid metabolism (HP:0010894)2.29099964
44Meckel diverticulum (HP:0002245)2.26390769
45Abnormality of the ileum (HP:0001549)2.24253374
46Abnormality of aspartate family amino acid metabolism (HP:0010899)2.24246191
47Congenital, generalized hypertrichosis (HP:0004540)2.23425517
48Microvesicular hepatic steatosis (HP:0001414)2.23421522
49Cerebellar dysplasia (HP:0007033)2.22071057
50Type II lissencephaly (HP:0007260)2.21936554
51Optic disc pallor (HP:0000543)2.21132811
52Severe combined immunodeficiency (HP:0004430)2.21043102
53Abnormality of the metopic suture (HP:0005556)2.20762561
54Renal Fanconi syndrome (HP:0001994)2.20683957
55CNS demyelination (HP:0007305)2.17352478
56Abnormality of the renal cortex (HP:0011035)2.13230075
57True hermaphroditism (HP:0010459)2.10639382
58Carpal bone hypoplasia (HP:0001498)2.09762011
59Abnormal rod and cone electroretinograms (HP:0008323)2.09403616
60Inability to walk (HP:0002540)2.08965284
61Abnormality of B cell number (HP:0010975)2.06441225
62Abnormality of the vitamin B12 metabolism (HP:0004341)2.03447457
63Hyperglycinuria (HP:0003108)2.03040948
64Hypokalemic alkalosis (HP:0001949)2.01663760
65Thyroiditis (HP:0100646)2.00761821
66Abnormality of vitamin B metabolism (HP:0004340)1.99763053
67IgG deficiency (HP:0004315)1.99011709
68Lethargy (HP:0001254)1.98522782
69Stomatitis (HP:0010280)1.98113204
70Colon cancer (HP:0003003)1.97196633
71Thoracolumbar scoliosis (HP:0002944)1.96193908
72Abnormality of midbrain morphology (HP:0002418)1.95751624
73Molar tooth sign on MRI (HP:0002419)1.95751624
74Abnormality of the fovea (HP:0000493)1.93884475
75Abnormality of methionine metabolism (HP:0010901)1.92721635
76Aplasia/hypoplasia of the humerus (HP:0006507)1.86277158
77Hypoplasia of the pons (HP:0012110)1.85223679
78Respiratory failure (HP:0002878)1.84612454
79Aplasia/Hypoplasia of the ulna (HP:0006495)1.83396299
80Absent rod-and cone-mediated responses on ERG (HP:0007688)1.83361480
81Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.83357585
82Submucous cleft hard palate (HP:0000176)1.82145095
83Aplasia/Hypoplasia of the uvula (HP:0010293)1.82042302
84Chorioretinal atrophy (HP:0000533)1.81619923
85Neuroblastic tumors (HP:0004376)1.81103942
86Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.81103942
87Neuroblastoma (HP:0003006)1.81103942
88Primitive neuroectodermal tumor (HP:0030065)1.81103942
89Choreoathetosis (HP:0001266)1.80431360
90Hypoplasia of the ulna (HP:0003022)1.79451981
91Abnormality of the pons (HP:0007361)1.76881261
92Poor suck (HP:0002033)1.75689649
93Abnormality of chromosome stability (HP:0003220)1.74740863
94Progressive microcephaly (HP:0000253)1.74145863
95Leukodystrophy (HP:0002415)1.71996276
96Polyuria (HP:0000103)1.71591768
97Congenital sensorineural hearing impairment (HP:0008527)1.71442812
98Tubulointerstitial nephritis (HP:0001970)1.71087714
99Combined immunodeficiency (HP:0005387)1.71073829
100Exertional dyspnea (HP:0002875)1.70488819

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K26.94171239
2TRIM285.24540825
3TSSK64.73462559
4SRPK13.43227771
5BCKDK2.96517663
6MST42.48815108
7AKT32.47236883
8SIK32.20069309
9EIF2AK32.09149355
10MKNK11.96336937
11NEK11.90722997
12TXK1.88492006
13ZAK1.84577658
14CSNK1G31.81102037
15CSNK1G11.69137653
16PASK1.62136947
17BCR1.62078819
18CSNK1G21.50264541
19CSNK1A1L1.49320749
20NUAK11.42312022
21EIF2AK11.39119942
22PLK31.36841789
23VRK21.36474345
24PBK1.31741257
25TGFBR11.30227748
26WNK31.28482161
27NME11.24274939
28MKNK21.24268797
29EIF2AK21.21358240
30MAP3K41.13890541
31ADRBK21.12419394
32GRK11.11596247
33TAF11.10584001
34WNK41.09834672
35TLK11.07021924
36TEC1.06417231
37OXSR11.03267169
38BMPR1B1.01528218
39KIT0.98914107
40CDK190.98286002
41EPHA30.97089306
42PLK40.96784549
43IKBKE0.93391450
44STK390.92698567
45CDC70.91819280
46MAP3K120.80095772
47GRK60.69931646
48VRK10.68824026
49FRK0.67713166
50MAPKAPK30.66354771
51JAK30.66271925
52PLK20.66027404
53PIK3CA0.65833420
54TAOK30.62011721
55ACVR1B0.59468242
56FGFR40.58063840
57TNIK0.57276213
58RIPK40.55383623
59TYK20.54062506
60TIE10.52523172
61ITK0.52109267
62FER0.50387315
63ALK0.49321587
64ATR0.49189882
65PRKCG0.47004422
66NLK0.46967736
67PLK10.45554648
68CSNK1A10.43984608
69RPS6KA40.42734952
70BRAF0.42651054
71CSNK2A10.41162030
72EPHA40.40070095
73PRKG10.39035345
74DAPK10.36226306
75CSNK2A20.35489330
76RPS6KA50.32957998
77CSNK1E0.32932473
78PINK10.32252851
79INSRR0.32144350
80STK30.30726134
81PRKCE0.30696126
82ATM0.29526875
83OBSCN0.29442121
84MAP3K110.28600506
85EGFR0.28079779
86PRKG20.27423295
87CCNB10.27031123
88CAMK2A0.26195706
89CAMK10.25706147
90DYRK20.25519867
91MAP2K70.25385050
92MAP2K60.25027547
93CSNK1D0.24600230
94TTK0.24520547
95STK38L0.23924825
96AURKB0.22044829
97BTK0.21917765
98IKBKB0.21521066
99ADRBK10.20509993
100FGFR10.20296656

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.92113444
2Protein export_Homo sapiens_hsa030603.06543096
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.80859742
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.69147847
5Propanoate metabolism_Homo sapiens_hsa006402.53993465
6Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.51504891
7RNA polymerase_Homo sapiens_hsa030202.28371782
8Steroid biosynthesis_Homo sapiens_hsa001002.23448885
9Basal transcription factors_Homo sapiens_hsa030222.22571778
10Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.20017895
11Oxidative phosphorylation_Homo sapiens_hsa001902.05879197
12Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.04264861
13Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.99853181
14RNA degradation_Homo sapiens_hsa030181.97769864
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.96845855
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.94962401
17Ribosome_Homo sapiens_hsa030101.89462316
18Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.88304500
19Phototransduction_Homo sapiens_hsa047441.76258776
20Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.75237663
21Parkinsons disease_Homo sapiens_hsa050121.75145812
22Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.73429716
23One carbon pool by folate_Homo sapiens_hsa006701.72838184
24Caffeine metabolism_Homo sapiens_hsa002321.70522870
25Spliceosome_Homo sapiens_hsa030401.67986655
26Sulfur metabolism_Homo sapiens_hsa009201.53112484
27Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.50743634
28Non-homologous end-joining_Homo sapiens_hsa034501.49838087
29Homologous recombination_Homo sapiens_hsa034401.45117427
30Nucleotide excision repair_Homo sapiens_hsa034201.42271902
31Mismatch repair_Homo sapiens_hsa034301.40667941
32RNA transport_Homo sapiens_hsa030131.32772164
33Huntingtons disease_Homo sapiens_hsa050161.28236716
34Fanconi anemia pathway_Homo sapiens_hsa034601.26619032
35Purine metabolism_Homo sapiens_hsa002301.24042518
36Cysteine and methionine metabolism_Homo sapiens_hsa002701.22692577
37Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.19230162
38Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.15920572
39Primary immunodeficiency_Homo sapiens_hsa053401.14974529
40Pyrimidine metabolism_Homo sapiens_hsa002401.09001690
41Butanoate metabolism_Homo sapiens_hsa006501.08031222
42Fatty acid elongation_Homo sapiens_hsa000621.07554448
43Base excision repair_Homo sapiens_hsa034101.05390791
44Peroxisome_Homo sapiens_hsa041461.02015407
45Nitrogen metabolism_Homo sapiens_hsa009100.99056585
46Linoleic acid metabolism_Homo sapiens_hsa005910.96583960
47Alzheimers disease_Homo sapiens_hsa050100.94050520
48Pyruvate metabolism_Homo sapiens_hsa006200.93983552
49Folate biosynthesis_Homo sapiens_hsa007900.93621089
50Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.90737173
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.84837545
52Tryptophan metabolism_Homo sapiens_hsa003800.83758083
53Regulation of autophagy_Homo sapiens_hsa041400.78240750
54SNARE interactions in vesicular transport_Homo sapiens_hsa041300.76976171
55Asthma_Homo sapiens_hsa053100.76162647
56Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.74367491
57Metabolic pathways_Homo sapiens_hsa011000.73580546
58alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.73013994
59Ether lipid metabolism_Homo sapiens_hsa005650.72829958
60Fat digestion and absorption_Homo sapiens_hsa049750.69390423
61Retinol metabolism_Homo sapiens_hsa008300.68573766
62NF-kappa B signaling pathway_Homo sapiens_hsa040640.66916819
63Circadian rhythm_Homo sapiens_hsa047100.66800166
64Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.64510593
65Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.64307880
66Fatty acid metabolism_Homo sapiens_hsa012120.63483634
67ABC transporters_Homo sapiens_hsa020100.62452304
68Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.62141832
69Fatty acid degradation_Homo sapiens_hsa000710.59578021
70p53 signaling pathway_Homo sapiens_hsa041150.58034138
71Pentose and glucuronate interconversions_Homo sapiens_hsa000400.57302086
72Nicotine addiction_Homo sapiens_hsa050330.55784074
73Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.50568287
74Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.50173011
75DNA replication_Homo sapiens_hsa030300.49996283
76Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.45437364
77Maturity onset diabetes of the young_Homo sapiens_hsa049500.44455220
78Steroid hormone biosynthesis_Homo sapiens_hsa001400.44137852
79Carbon metabolism_Homo sapiens_hsa012000.43872236
80Morphine addiction_Homo sapiens_hsa050320.42314662
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.40187120
82N-Glycan biosynthesis_Homo sapiens_hsa005100.39254799
83Vitamin digestion and absorption_Homo sapiens_hsa049770.39143510
84mRNA surveillance pathway_Homo sapiens_hsa030150.38444551
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.36977232
86Cardiac muscle contraction_Homo sapiens_hsa042600.36364515
87Hematopoietic cell lineage_Homo sapiens_hsa046400.36261071
88Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.33963707
89beta-Alanine metabolism_Homo sapiens_hsa004100.32789433
90Olfactory transduction_Homo sapiens_hsa047400.32780156
91Biosynthesis of amino acids_Homo sapiens_hsa012300.31224629
92Selenocompound metabolism_Homo sapiens_hsa004500.31187025
93Type I diabetes mellitus_Homo sapiens_hsa049400.30830322
94Chemical carcinogenesis_Homo sapiens_hsa052040.30310428
95Serotonergic synapse_Homo sapiens_hsa047260.30294800
96Oocyte meiosis_Homo sapiens_hsa041140.29129741
97Glutathione metabolism_Homo sapiens_hsa004800.25670768
98GABAergic synapse_Homo sapiens_hsa047270.24538117
99Epstein-Barr virus infection_Homo sapiens_hsa051690.24272695
100Glycerolipid metabolism_Homo sapiens_hsa005610.22315363

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »