Rank | Gene Set | Z-score |
---|---|---|
1 | DNA unwinding involved in DNA replication (GO:0006268) | 5.31977373 |
2 | pore complex assembly (GO:0046931) | 4.75093699 |
3 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.32781050 |
4 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 4.16483423 |
5 | DNA strand elongation (GO:0022616) | 4.14263636 |
6 | peptidyl-arginine omega-N-methylation (GO:0035247) | 4.11863363 |
7 | COPI coating of Golgi vesicle (GO:0048205) | 4.11318188 |
8 | Golgi transport vesicle coating (GO:0048200) | 4.11318188 |
9 | RNA stabilization (GO:0043489) | 4.04421293 |
10 | mRNA stabilization (GO:0048255) | 4.04421293 |
11 | protein localization to kinetochore (GO:0034501) | 3.99847471 |
12 | DNA replication initiation (GO:0006270) | 3.97760403 |
13 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.95104013 |
14 | regulation of RNA export from nucleus (GO:0046831) | 3.94554885 |
15 | establishment of viral latency (GO:0019043) | 3.89204159 |
16 | peptidyl-arginine N-methylation (GO:0035246) | 3.87816267 |
17 | peptidyl-arginine methylation (GO:0018216) | 3.87816267 |
18 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.87292291 |
19 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.85052243 |
20 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 3.79418149 |
21 | protein-DNA complex disassembly (GO:0032986) | 3.76336939 |
22 | nucleosome disassembly (GO:0006337) | 3.76336939 |
23 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.76210761 |
24 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.76210761 |
25 | CENP-A containing nucleosome assembly (GO:0034080) | 3.74948873 |
26 | mitotic recombination (GO:0006312) | 3.73686583 |
27 | DNA topological change (GO:0006265) | 3.70845893 |
28 | chromatin remodeling at centromere (GO:0031055) | 3.68149210 |
29 | nuclear pore organization (GO:0006999) | 3.67024850 |
30 | kinetochore organization (GO:0051383) | 3.65736553 |
31 | DNA replication-independent nucleosome organization (GO:0034724) | 3.64764116 |
32 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.64764116 |
33 | mitotic chromosome condensation (GO:0007076) | 3.57012236 |
34 | nucleobase biosynthetic process (GO:0046112) | 3.56848008 |
35 | heterochromatin organization (GO:0070828) | 3.54884943 |
36 | negative regulation of RNA splicing (GO:0033119) | 3.54762837 |
37 | telomere maintenance via recombination (GO:0000722) | 3.51803109 |
38 | mitotic metaphase plate congression (GO:0007080) | 3.49742079 |
39 | sister chromatid segregation (GO:0000819) | 3.49592527 |
40 | regulation of translational fidelity (GO:0006450) | 3.48261232 |
41 | viral mRNA export from host cell nucleus (GO:0046784) | 3.46536226 |
42 | IMP biosynthetic process (GO:0006188) | 3.43742013 |
43 | nuclear pore complex assembly (GO:0051292) | 3.42428770 |
44 | mitotic nuclear envelope disassembly (GO:0007077) | 3.42171719 |
45 | spindle assembly checkpoint (GO:0071173) | 3.39699872 |
46 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.38940007 |
47 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.38839593 |
48 | negative regulation of sister chromatid segregation (GO:0033046) | 3.38839593 |
49 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.38839593 |
50 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.38839593 |
51 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.38775050 |
52 | protein complex localization (GO:0031503) | 3.37985580 |
53 | mitotic spindle assembly checkpoint (GO:0007094) | 3.37720591 |
54 | purine nucleobase biosynthetic process (GO:0009113) | 3.37412096 |
55 | DNA duplex unwinding (GO:0032508) | 3.34575581 |
56 | postreplication repair (GO:0006301) | 3.34364693 |
57 | DNA geometric change (GO:0032392) | 3.33783201 |
58 | negative regulation of chromosome segregation (GO:0051985) | 3.33728891 |
59 | histone arginine methylation (GO:0034969) | 3.32990674 |
60 | V(D)J recombination (GO:0033151) | 3.31125524 |
61 | establishment of integrated proviral latency (GO:0075713) | 3.30941072 |
62 | pre-miRNA processing (GO:0031054) | 3.30573702 |
63 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.30368635 |
64 | protein localization to chromosome, centromeric region (GO:0071459) | 3.30220154 |
65 | negative regulation of mRNA processing (GO:0050686) | 3.29980652 |
66 | DNA replication checkpoint (GO:0000076) | 3.28303958 |
67 | regulation of mRNA stability (GO:0043488) | 3.28220297 |
68 | mitotic sister chromatid segregation (GO:0000070) | 3.27742644 |
69 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.27604985 |
70 | spindle checkpoint (GO:0031577) | 3.26724843 |
71 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.26513511 |
72 | metaphase plate congression (GO:0051310) | 3.24414338 |
73 | formation of translation preinitiation complex (GO:0001731) | 3.23331547 |
74 | histone H2A acetylation (GO:0043968) | 3.22681069 |
75 | * mRNA splicing, via spliceosome (GO:0000398) | 3.22063854 |
76 | * RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 3.22063854 |
77 | dosage compensation (GO:0007549) | 3.21633885 |
78 | mitotic spindle checkpoint (GO:0071174) | 3.21456994 |
79 | * RNA splicing, via transesterification reactions (GO:0000375) | 3.20105674 |
80 | membrane disassembly (GO:0030397) | 3.19310287 |
81 | nuclear envelope disassembly (GO:0051081) | 3.19310287 |
82 | telomere maintenance via telomere lengthening (GO:0010833) | 3.18956203 |
83 | translesion synthesis (GO:0019985) | 3.17530401 |
84 | mitotic sister chromatid cohesion (GO:0007064) | 3.16959598 |
85 | histone exchange (GO:0043486) | 3.16875393 |
86 | paraxial mesoderm development (GO:0048339) | 3.16316759 |
87 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.13742204 |
88 | ATP-dependent chromatin remodeling (GO:0043044) | 3.12776333 |
89 | regulation of chromosome segregation (GO:0051983) | 3.12714161 |
90 | non-recombinational repair (GO:0000726) | 3.12631251 |
91 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.12631251 |
92 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.11581122 |
93 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.11581122 |
94 | cellular protein complex localization (GO:0034629) | 3.11414075 |
95 | protein export from nucleus (GO:0006611) | 3.11161202 |
96 | chromosome condensation (GO:0030261) | 3.11060964 |
97 | establishment of chromosome localization (GO:0051303) | 3.08309390 |
98 | cellular hyperosmotic response (GO:0071474) | 3.05972255 |
99 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.05631312 |
100 | regulation of sister chromatid segregation (GO:0033045) | 3.03921973 |
101 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.03921973 |
102 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.03921973 |
103 | regulation of RNA stability (GO:0043487) | 3.03432600 |
104 | spliceosomal complex assembly (GO:0000245) | 3.01772433 |
105 | spliceosomal snRNP assembly (GO:0000387) | 3.01698200 |
106 | regulation of spindle organization (GO:0090224) | 3.01240602 |
107 | cullin deneddylation (GO:0010388) | 3.00642127 |
108 | regulation of mitotic spindle organization (GO:0060236) | 3.00604985 |
109 | kinetochore assembly (GO:0051382) | 3.00030830 |
110 | histone H2B ubiquitination (GO:0033523) | 2.98817852 |
111 | mismatch repair (GO:0006298) | 2.95906015 |
112 | mRNA transport (GO:0051028) | 2.95793220 |
113 | nuclear envelope organization (GO:0006998) | 2.94006769 |
114 | protein localization to chromosome (GO:0034502) | 2.92711433 |
115 | IMP metabolic process (GO:0046040) | 2.90406150 |
116 | DNA ligation (GO:0006266) | 2.90348718 |
117 | termination of RNA polymerase II transcription (GO:0006369) | 2.88595635 |
118 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.86979083 |
119 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.86933857 |
120 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 2.86731880 |
121 | RNA export from nucleus (GO:0006405) | 2.85510143 |
122 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.85058218 |
123 | regulation of helicase activity (GO:0051095) | 2.84572737 |
124 | regulation of centrosome cycle (GO:0046605) | 2.84357020 |
125 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.83026163 |
126 | embryonic process involved in female pregnancy (GO:0060136) | 2.82860465 |
127 | pentose-phosphate shunt (GO:0006098) | 2.82552105 |
128 | DNA conformation change (GO:0071103) | 2.81500381 |
129 | DNA double-strand break processing (GO:0000729) | 2.81249186 |
130 | mRNA export from nucleus (GO:0006406) | 2.80460942 |
131 | positive regulation of RNA splicing (GO:0033120) | 2.79678087 |
132 | intra-S DNA damage checkpoint (GO:0031573) | 2.79232088 |
133 | chromatin assembly or disassembly (GO:0006333) | 2.77252171 |
134 | negative regulation of mRNA metabolic process (GO:1903312) | 2.76533253 |
135 | regulation of sister chromatid cohesion (GO:0007063) | 2.76214591 |
136 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.76119084 |
137 | negative regulation of mitosis (GO:0045839) | 2.75289354 |
138 | positive regulation of cell cycle checkpoint (GO:1901978) | 2.75037507 |
139 | chromosome segregation (GO:0007059) | 2.74617245 |
140 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.73665285 |
141 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.73482825 |
142 | negative regulation of histone methylation (GO:0031061) | 2.72390849 |
143 | regulation of DNA damage checkpoint (GO:2000001) | 2.71578204 |
144 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.68460216 |
145 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.67975731 |
146 | NADPH regeneration (GO:0006740) | 2.67651042 |
147 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.66579038 |
148 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling | 2.66310255 |
149 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 2.66310255 |
150 | positive regulation of chromosome segregation (GO:0051984) | 2.66207060 |
151 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.64317578 |
152 | negative regulation of DNA repair (GO:0045738) | 2.63080813 |
153 | DNA packaging (GO:0006323) | 2.61529043 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 9.77087550 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.66214886 |
3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.29185727 |
4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.01677846 |
5 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.40333268 |
6 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.23942958 |
7 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.17538448 |
8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.95788844 |
9 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.90567472 |
10 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.80292307 |
11 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.73333225 |
12 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.68970299 |
13 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.65344744 |
14 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.60752518 |
15 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.59079529 |
16 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.58502596 |
17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.50285149 |
18 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.49828073 |
19 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.46164871 |
20 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.46067557 |
21 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.40467700 |
22 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.35786126 |
23 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.34947725 |
24 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.32264661 |
25 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.31739878 |
26 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.30663784 |
27 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.24146457 |
28 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.19217702 |
29 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.15625769 |
30 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.14176183 |
31 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.13133550 |
32 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.11018649 |
33 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.08368715 |
34 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 2.03047602 |
35 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.99047492 |
36 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.97983495 |
37 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.97380197 |
38 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.93790675 |
39 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.92374474 |
40 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.90471813 |
41 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.89650925 |
42 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.88455397 |
43 | * CIITA_25753668_ChIP-Seq_RAJI_Human | 1.85625265 |
44 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.83669137 |
45 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.78801647 |
46 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.76622159 |
47 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.75622795 |
48 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.74768459 |
49 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.71864567 |
50 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.70478510 |
51 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.68902142 |
52 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.65374736 |
53 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.63467314 |
54 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.63302003 |
55 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.52938513 |
56 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.50660327 |
57 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46729972 |
58 | MYC_22102868_ChIP-Seq_BL_Human | 1.46719151 |
59 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.40698015 |
60 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.39926331 |
61 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.39690700 |
62 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.35549544 |
63 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.35469813 |
64 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.34107126 |
65 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.33425897 |
66 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.33372278 |
67 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.27417832 |
68 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.26235292 |
69 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.26210016 |
70 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.25720241 |
71 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.25501828 |
72 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.25165196 |
73 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.24125009 |
74 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.22451688 |
75 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.21275636 |
76 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.21165274 |
77 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.21150005 |
78 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.20424636 |
79 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.19531981 |
80 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.19424879 |
81 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.18642977 |
82 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.17712373 |
83 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.16204486 |
84 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14733293 |
85 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.14466859 |
86 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.14405593 |
87 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.14373938 |
88 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.14143318 |
89 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.13634204 |
90 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.13580634 |
91 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.13252499 |
92 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.12490569 |
93 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.10788252 |
94 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.08570440 |
95 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 1.08492570 |
96 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.08463413 |
97 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.06895643 |
98 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.05773661 |
99 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.05501528 |
100 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.02395858 |
101 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.02373376 |
102 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.01480307 |
103 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.99996724 |
104 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.99733649 |
105 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.99068706 |
106 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.98943007 |
107 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.98380263 |
108 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.97504430 |
109 | MAF_26560356_Chip-Seq_TH1_Human | 0.94778003 |
110 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.94586260 |
111 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.94440381 |
112 | * DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.93274951 |
113 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.92120603 |
114 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.91916275 |
115 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.91345034 |
116 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.91309353 |
117 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.90181237 |
118 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.89729846 |
119 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.88171060 |
120 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.87782057 |
121 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.87446767 |
122 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87148179 |
123 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.87106315 |
124 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.86920418 |
125 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.86188338 |
126 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.85527831 |
127 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.81716943 |
128 | EWS_26573619_Chip-Seq_HEK293_Human | 0.80173656 |
129 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.79171978 |
130 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.76115830 |
131 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.76077804 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010094_abnormal_chromosome_stability | 4.00941319 |
2 | MP0003693_abnormal_embryo_hatching | 3.73001432 |
3 | MP0004957_abnormal_blastocyst_morpholog | 3.54891552 |
4 | MP0003111_abnormal_nucleus_morphology | 3.45914809 |
5 | MP0008057_abnormal_DNA_replication | 3.43205589 |
6 | MP0002009_preneoplasia | 3.42011454 |
7 | MP0003077_abnormal_cell_cycle | 3.35065457 |
8 | MP0003123_paternal_imprinting | 2.98834638 |
9 | MP0008007_abnormal_cellular_replicative | 2.94288261 |
10 | MP0008058_abnormal_DNA_repair | 2.93831359 |
11 | MP0002877_abnormal_melanocyte_morpholog | 2.64691990 |
12 | MP0003121_genomic_imprinting | 2.52113288 |
13 | MP0008932_abnormal_embryonic_tissue | 2.48032776 |
14 | MP0003705_abnormal_hypodermis_morpholog | 2.41222076 |
15 | MP0010030_abnormal_orbit_morphology | 2.33513938 |
16 | MP0000537_abnormal_urethra_morphology | 2.31313790 |
17 | MP0003221_abnormal_cardiomyocyte_apopto | 2.18563058 |
18 | MP0008877_abnormal_DNA_methylation | 2.11920799 |
19 | MP0001730_embryonic_growth_arrest | 2.03926910 |
20 | MP0010234_abnormal_vibrissa_follicle | 1.98481306 |
21 | MP0000350_abnormal_cell_proliferation | 1.96829094 |
22 | MP0006054_spinal_hemorrhage | 1.94078283 |
23 | MP0009053_abnormal_anal_canal | 1.89577815 |
24 | MP0003122_maternal_imprinting | 1.71253503 |
25 | MP0002396_abnormal_hematopoietic_system | 1.70913129 |
26 | MP0001293_anophthalmia | 1.68727174 |
27 | MP0003890_abnormal_embryonic-extraembry | 1.65271762 |
28 | MP0001697_abnormal_embryo_size | 1.62735705 |
29 | MP0002938_white_spotting | 1.62401269 |
30 | MP0002085_abnormal_embryonic_tissue | 1.61026710 |
31 | MP0002084_abnormal_developmental_patter | 1.60844418 |
32 | MP0003566_abnormal_cell_adhesion | 1.60329660 |
33 | MP0003786_premature_aging | 1.55620675 |
34 | MP0004185_abnormal_adipocyte_glucose | 1.55014044 |
35 | MP0003315_abnormal_perineum_morphology | 1.54502131 |
36 | MP0004197_abnormal_fetal_growth/weight/ | 1.51361150 |
37 | MP0001672_abnormal_embryogenesis/_devel | 1.51161724 |
38 | MP0005380_embryogenesis_phenotype | 1.51161724 |
39 | MP0010352_gastrointestinal_tract_polyps | 1.50565867 |
40 | MP0000566_synostosis | 1.45282637 |
41 | MP0003937_abnormal_limbs/digits/tail_de | 1.43765772 |
42 | MP0004808_abnormal_hematopoietic_stem | 1.39122323 |
43 | MP0002080_prenatal_lethality | 1.39074093 |
44 | MP0003984_embryonic_growth_retardation | 1.37129483 |
45 | MP0000049_abnormal_middle_ear | 1.35615811 |
46 | MP0002088_abnormal_embryonic_growth/wei | 1.34624867 |
47 | MP0003119_abnormal_digestive_system | 1.31432790 |
48 | MP0003942_abnormal_urinary_system | 1.29167995 |
49 | MP0002653_abnormal_ependyma_morphology | 1.27716107 |
50 | MP0005501_abnormal_skin_physiology | 1.24903064 |
51 | MP0001346_abnormal_lacrimal_gland | 1.23807011 |
52 | MP0002796_impaired_skin_barrier | 1.21466061 |
53 | MP0003567_abnormal_fetal_cardiomyocyte | 1.20356380 |
54 | MP0004264_abnormal_extraembryonic_tissu | 1.19423501 |
55 | MP0003787_abnormal_imprinting | 1.19406381 |
56 | MP0008789_abnormal_olfactory_epithelium | 1.19123001 |
57 | MP0005623_abnormal_meninges_morphology | 1.18262125 |
58 | MP0002282_abnormal_trachea_morphology | 1.17002172 |
59 | MP0008260_abnormal_autophagy | 1.16845545 |
60 | MP0002751_abnormal_autonomic_nervous | 1.16807340 |
61 | MP0002102_abnormal_ear_morphology | 1.15320180 |
62 | MP0003115_abnormal_respiratory_system | 1.15169688 |
63 | MP0002086_abnormal_extraembryonic_tissu | 1.14237282 |
64 | MP0005248_abnormal_Harderian_gland | 1.13874193 |
65 | MP0005621_abnormal_cell_physiology | 1.13630270 |
66 | MP0000490_abnormal_crypts_of | 1.12532824 |
67 | MP0000428_abnormal_craniofacial_morphol | 1.12432683 |
68 | MP0000313_abnormal_cell_death | 1.10816875 |
69 | MP0010307_abnormal_tumor_latency | 1.08979567 |
70 | MP0002111_abnormal_tail_morphology | 1.07662865 |
71 | MP0006292_abnormal_olfactory_placode | 1.06846373 |
72 | MP0005076_abnormal_cell_differentiation | 1.06804512 |
73 | MP0003091_abnormal_cell_migration | 1.06721117 |
74 | MP0001286_abnormal_eye_development | 1.06259743 |
75 | MP0002210_abnormal_sex_determination | 1.04812161 |
76 | MP0003300_gastrointestinal_ulcer | 1.04326262 |
77 | MP0002166_altered_tumor_susceptibility | 1.03066599 |
78 | MP0009697_abnormal_copulation | 1.02321656 |
79 | MP0003385_abnormal_body_wall | 1.01660516 |
80 | MP0002092_abnormal_eye_morphology | 1.01580405 |
81 | MP0003861_abnormal_nervous_system | 1.00988003 |
82 | MP0004782_abnormal_surfactant_physiolog | 1.00136146 |
83 | MP0003755_abnormal_palate_morphology | 1.00020445 |
84 | MP0000534_abnormal_ureter_morphology | 0.98965120 |
85 | MP0001727_abnormal_embryo_implantation | 0.98451898 |
86 | MP0004133_heterotaxia | 0.97329286 |
87 | MP0005384_cellular_phenotype | 0.96119888 |
88 | MP0002932_abnormal_joint_morphology | 0.96078499 |
89 | MP0001849_ear_inflammation | 0.95274078 |
90 | MP0003935_abnormal_craniofacial_develop | 0.95242261 |
91 | MP0009278_abnormal_bone_marrow | 0.92921899 |
92 | MP0001145_abnormal_male_reproductive | 0.90115863 |
93 | MP0000579_abnormal_nail_morphology | 0.89461954 |
94 | MP0003763_abnormal_thymus_physiology | 0.89316753 |
95 | MP0001340_abnormal_eyelid_morphology | 0.89160392 |
96 | MP0000703_abnormal_thymus_morphology | 0.87892370 |
97 | MP0002019_abnormal_tumor_incidence | 0.87575895 |
98 | MP0003943_abnormal_hepatobiliary_system | 0.87506760 |
99 | MP0006072_abnormal_retinal_apoptosis | 0.87487399 |
100 | MP0002697_abnormal_eye_size | 0.86726038 |
101 | MP0002116_abnormal_craniofacial_bone | 0.86714175 |
102 | MP0003283_abnormal_digestive_organ | 0.86133752 |
103 | MP0009250_abnormal_appendicular_skeleto | 0.85697482 |
104 | MP0005451_abnormal_body_composition | 0.85154235 |
105 | MP0002006_tumorigenesis | 0.83155603 |
106 | MP0002098_abnormal_vibrissa_morphology | 0.82926039 |
107 | MP0002233_abnormal_nose_morphology | 0.81212541 |
108 | MP0000631_abnormal_neuroendocrine_gland | 0.80351472 |
109 | MP0002114_abnormal_axial_skeleton | 0.79808898 |
110 | MP0000377_abnormal_hair_follicle | 0.79719063 |
111 | MP0003938_abnormal_ear_development | 0.79145263 |
112 | MP0000733_abnormal_muscle_development | 0.78891944 |
113 | MP0005391_vision/eye_phenotype | 0.78779282 |
114 | MP0004858_abnormal_nervous_system | 0.78716173 |
115 | MP0003941_abnormal_skin_development | 0.77956907 |
116 | MP0003453_abnormal_keratinocyte_physiol | 0.77568894 |
117 | MP0001529_abnormal_vocalization | 0.76690091 |
118 | MP0004233_abnormal_muscle_weight | 0.76621304 |
119 | MP0002160_abnormal_reproductive_system | 0.76368566 |
120 | MP0000432_abnormal_head_morphology | 0.76338302 |
121 | MP0000569_abnormal_digit_pigmentation | 0.75857769 |
122 | MP0000858_altered_metastatic_potential | 0.75704629 |
123 | MP0009703_decreased_birth_body | 0.75612765 |
124 | MP0010630_abnormal_cardiac_muscle | 0.75219028 |
125 | MP0009672_abnormal_birth_weight | 0.74887962 |
126 | MP0001216_abnormal_epidermal_layer | 0.74464630 |
127 | MP0005394_taste/olfaction_phenotype | 0.74318110 |
128 | MP0005499_abnormal_olfactory_system | 0.74318110 |
129 | MP0002234_abnormal_pharynx_morphology | 0.73151315 |
130 | MP0000653_abnormal_sex_gland | 0.72929669 |
131 | MP0001915_intracranial_hemorrhage | 0.72462207 |
132 | MP0002095_abnormal_skin_pigmentation | 0.71606452 |
133 | MP0004134_abnormal_chest_morphology | 0.71081779 |
134 | MP0002081_perinatal_lethality | 0.70396352 |
135 | MP0002177_abnormal_outer_ear | 0.68932104 |
136 | MP0001929_abnormal_gametogenesis | 0.67892245 |
137 | MP0000477_abnormal_intestine_morphology | 0.67849348 |
138 | MP0001188_hyperpigmentation | 0.67688419 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Cortical dysplasia (HP:0002539) | 4.09193607 |
2 | Colon cancer (HP:0003003) | 3.49893658 |
3 | Hyperacusis (HP:0010780) | 3.41698115 |
4 | Medulloblastoma (HP:0002885) | 3.24419708 |
5 | Short 4th metacarpal (HP:0010044) | 3.21935500 |
6 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 3.21935500 |
7 | Birth length less than 3rd percentile (HP:0003561) | 3.19672427 |
8 | Degeneration of anterior horn cells (HP:0002398) | 3.13337538 |
9 | Abnormality of the anterior horn cell (HP:0006802) | 3.13337538 |
10 | Termporal pattern (HP:0011008) | 3.09134803 |
11 | Insidious onset (HP:0003587) | 3.09134803 |
12 | Ependymoma (HP:0002888) | 2.98927728 |
13 | Selective tooth agenesis (HP:0001592) | 2.95054220 |
14 | Insomnia (HP:0100785) | 2.94715721 |
15 | Patellar aplasia (HP:0006443) | 2.92732984 |
16 | Volvulus (HP:0002580) | 2.87284319 |
17 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.79387779 |
18 | Abnormal lung lobation (HP:0002101) | 2.79046094 |
19 | Increased nuchal translucency (HP:0010880) | 2.77612797 |
20 | Spastic diplegia (HP:0001264) | 2.77152559 |
21 | Abnormal number of incisors (HP:0011064) | 2.70977529 |
22 | 11 pairs of ribs (HP:0000878) | 2.66789736 |
23 | Abnormality of the labia minora (HP:0012880) | 2.64170237 |
24 | Proximal placement of thumb (HP:0009623) | 2.60961013 |
25 | Shoulder girdle muscle weakness (HP:0003547) | 2.53355010 |
26 | Deviation of the thumb (HP:0009603) | 2.51906106 |
27 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.38034265 |
28 | Asymmetry of the thorax (HP:0001555) | 2.37458918 |
29 | Overlapping toe (HP:0001845) | 2.34881288 |
30 | Syringomyelia (HP:0003396) | 2.30635314 |
31 | Spinal cord lesions (HP:0100561) | 2.30635314 |
32 | Embryonal renal neoplasm (HP:0011794) | 2.30407001 |
33 | Duodenal stenosis (HP:0100867) | 2.30092627 |
34 | Small intestinal stenosis (HP:0012848) | 2.30092627 |
35 | Agnosia (HP:0010524) | 2.29150258 |
36 | Chromsome breakage (HP:0040012) | 2.28774051 |
37 | Overriding aorta (HP:0002623) | 2.28432782 |
38 | Abnormality of chromosome stability (HP:0003220) | 2.27461923 |
39 | Meckel diverticulum (HP:0002245) | 2.26406443 |
40 | Neoplasm of the pancreas (HP:0002894) | 2.24196206 |
41 | Leiomyosarcoma (HP:0100243) | 2.23728354 |
42 | Uterine leiomyosarcoma (HP:0002891) | 2.23728354 |
43 | Abnormality of the 4th metacarpal (HP:0010012) | 2.23586432 |
44 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.22271512 |
45 | Pelvic girdle muscle weakness (HP:0003749) | 2.22271448 |
46 | Abnormality of the ileum (HP:0001549) | 2.21676663 |
47 | Optic nerve coloboma (HP:0000588) | 2.20026499 |
48 | Vertebral arch anomaly (HP:0008438) | 2.14986549 |
49 | Atresia of the external auditory canal (HP:0000413) | 2.14787330 |
50 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.13670179 |
51 | Reticulocytopenia (HP:0001896) | 2.10270039 |
52 | Renal duplication (HP:0000075) | 2.09402001 |
53 | Ankyloglossia (HP:0010296) | 2.08295415 |
54 | Large earlobe (HP:0009748) | 2.07525153 |
55 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.07206681 |
56 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.07178158 |
57 | Abnormality of the duodenum (HP:0002246) | 2.06562012 |
58 | Subacute progressive viral hepatitis (HP:0006572) | 2.06523382 |
59 | Abnormality of the astrocytes (HP:0100707) | 2.06485292 |
60 | Astrocytoma (HP:0009592) | 2.06485292 |
61 | Pseudobulbar signs (HP:0002200) | 2.06467144 |
62 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.06436689 |
63 | Oral leukoplakia (HP:0002745) | 2.05296722 |
64 | Broad face (HP:0000283) | 2.04809232 |
65 | Aplastic anemia (HP:0001915) | 2.03834430 |
66 | Long palpebral fissure (HP:0000637) | 2.03718732 |
67 | Ovarian neoplasm (HP:0100615) | 2.02420169 |
68 | Breast hypoplasia (HP:0003187) | 2.02073499 |
69 | Intestinal atresia (HP:0011100) | 2.02041782 |
70 | Abnormality of oral frenula (HP:0000190) | 2.01746759 |
71 | Missing ribs (HP:0000921) | 2.01421351 |
72 | Abnormality of the preputium (HP:0100587) | 2.00851613 |
73 | Arnold-Chiari malformation (HP:0002308) | 2.00655570 |
74 | Neoplasm of the colon (HP:0100273) | 1.98902230 |
75 | Absent radius (HP:0003974) | 1.98367558 |
76 | Ectopic kidney (HP:0000086) | 1.98363113 |
77 | Elfin facies (HP:0004428) | 1.97217267 |
78 | Pointed chin (HP:0000307) | 1.94566884 |
79 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.94190967 |
80 | Myelodysplasia (HP:0002863) | 1.92113087 |
81 | Progressive external ophthalmoplegia (HP:0000590) | 1.92056354 |
82 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.91845935 |
83 | Heterotopia (HP:0002282) | 1.91653809 |
84 | Hepatoblastoma (HP:0002884) | 1.90969017 |
85 | Glioma (HP:0009733) | 1.89807383 |
86 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.88951804 |
87 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.88951804 |
88 | Metaphyseal cupping (HP:0003021) | 1.88671909 |
89 | Aplasia involving forearm bones (HP:0009822) | 1.88005239 |
90 | Absent forearm bone (HP:0003953) | 1.88005239 |
91 | Distal lower limb amyotrophy (HP:0008944) | 1.86678049 |
92 | Premature graying of hair (HP:0002216) | 1.86671820 |
93 | Orthostatic hypotension (HP:0001278) | 1.86496655 |
94 | Spina bifida occulta (HP:0003298) | 1.85473575 |
95 | Sloping forehead (HP:0000340) | 1.84807632 |
96 | High anterior hairline (HP:0009890) | 1.84658415 |
97 | Abnormality of the calcaneus (HP:0008364) | 1.82038965 |
98 | Broad distal phalanx of finger (HP:0009836) | 1.80870293 |
99 | Flat acetabular roof (HP:0003180) | 1.79506319 |
100 | Supernumerary spleens (HP:0009799) | 1.76634829 |
101 | Obsessive-compulsive behavior (HP:0000722) | 1.76517418 |
102 | Microvesicular hepatic steatosis (HP:0001414) | 1.76434143 |
103 | Limb-girdle muscle atrophy (HP:0003797) | 1.76398536 |
104 | Short middle phalanx of the 5th finger (HP:0004220) | 1.76339153 |
105 | Bladder carcinoma (HP:0002862) | 1.76274192 |
106 | Bladder neoplasm (HP:0009725) | 1.76274192 |
107 | Basal cell carcinoma (HP:0002671) | 1.75864764 |
108 | Back pain (HP:0003418) | 1.75645881 |
109 | Neoplasm of the oral cavity (HP:0100649) | 1.74565427 |
110 | Glossoptosis (HP:0000162) | 1.74355366 |
111 | Patellar dislocation (HP:0002999) | 1.73355257 |
112 | Reticulocytosis (HP:0001923) | 1.72628974 |
113 | Neoplasm of the rectum (HP:0100743) | 1.71342404 |
114 | Freckling (HP:0001480) | 1.70137635 |
115 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.70052914 |
116 | Viral hepatitis (HP:0006562) | 1.69778458 |
117 | Rhabdomyosarcoma (HP:0002859) | 1.69154441 |
118 | Skull defect (HP:0001362) | 1.68594386 |
119 | Abnormality of the metopic suture (HP:0005556) | 1.67704008 |
120 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.66959562 |
121 | Multiple enchondromatosis (HP:0005701) | 1.66115625 |
122 | Facial hemangioma (HP:0000329) | 1.65981499 |
123 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.65800370 |
124 | Rimmed vacuoles (HP:0003805) | 1.65474851 |
125 | Biliary tract neoplasm (HP:0100574) | 1.65204177 |
126 | Facial cleft (HP:0002006) | 1.64785386 |
127 | Horseshoe kidney (HP:0000085) | 1.64440883 |
128 | Papillary thyroid carcinoma (HP:0002895) | 1.64089362 |
129 | Trigonocephaly (HP:0000243) | 1.63951353 |
130 | Broad alveolar ridges (HP:0000187) | 1.63408405 |
131 | Amaurosis fugax (HP:0100576) | 1.62961892 |
132 | Embryonal neoplasm (HP:0002898) | 1.62739218 |
133 | Rough bone trabeculation (HP:0100670) | 1.62446236 |
134 | Carpal bone hypoplasia (HP:0001498) | 1.62263640 |
135 | Cutis marmorata (HP:0000965) | 1.61930176 |
136 | Renovascular hypertension (HP:0100817) | 1.61390621 |
137 | Gastrointestinal atresia (HP:0002589) | 1.61247370 |
138 | Lower limb amyotrophy (HP:0007210) | 1.60804972 |
139 | Relative macrocephaly (HP:0004482) | 1.60532481 |
140 | Abnormality of the carotid arteries (HP:0005344) | 1.59747791 |
141 | Triphalangeal thumb (HP:0001199) | 1.59286289 |
142 | Flared metaphyses (HP:0003015) | 1.58875530 |
143 | Tracheoesophageal fistula (HP:0002575) | 1.58495578 |
144 | Bone marrow hypocellularity (HP:0005528) | 1.58481925 |
145 | Preaxial hand polydactyly (HP:0001177) | 1.58206646 |
146 | Cerebral hypomyelination (HP:0006808) | 1.57339007 |
147 | Gastrointestinal carcinoma (HP:0002672) | 1.56793029 |
148 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.56793029 |
149 | Abnormality of the intervertebral disk (HP:0005108) | 1.56663761 |
150 | Deep philtrum (HP:0002002) | 1.56317746 |
151 | Neoplasm of the small intestine (HP:0100833) | 1.56259073 |
152 | Intestinal polyp (HP:0005266) | 1.56189932 |
153 | Abnormal foot bone ossification (HP:0010675) | 1.55905707 |
154 | Generalized hypotonia (HP:0001290) | 1.55780265 |
155 | Esophageal atresia (HP:0002032) | 1.55568093 |
156 | Abnormality of chromosome segregation (HP:0002916) | 1.55067190 |
157 | Broad palm (HP:0001169) | 1.54697171 |
158 | Hammertoe (HP:0001765) | 1.54010285 |
159 | Neuroblastic tumors (HP:0004376) | 1.53132938 |
160 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 1.53132938 |
161 | Neuroblastoma (HP:0003006) | 1.53132938 |
162 | Primitive neuroectodermal tumor (HP:0030065) | 1.53132938 |
163 | Renal cell carcinoma (HP:0005584) | 1.53001650 |
164 | Omphalocele (HP:0001539) | 1.52807629 |
165 | Abnormality of the salivary glands (HP:0010286) | 1.52177541 |
166 | Coarctation of aorta (HP:0001680) | 1.49905201 |
167 | Disproportionate tall stature (HP:0001519) | 1.49131938 |
168 | Ulnar bowing (HP:0003031) | 1.47832740 |
169 | Radioulnar synostosis (HP:0002974) | 1.47477448 |
170 | Abnormality of reticulocytes (HP:0004312) | 1.47439426 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 4.73398483 |
2 | CDC7 | 4.43611333 |
3 | WEE1 | 3.65064427 |
4 | TSSK6 | 3.21398819 |
5 | SMG1 | 2.94092440 |
6 | MKNK1 | 2.93826321 |
7 | PASK | 2.93163144 |
8 | SRPK1 | 2.88970745 |
9 | EIF2AK1 | 2.71247631 |
10 | ACVR1B | 2.60938393 |
11 | TRIB3 | 2.27259330 |
12 | TGFBR1 | 2.18421072 |
13 | BRSK2 | 2.16411772 |
14 | CCNB1 | 2.08036043 |
15 | PRPF4B | 2.04690589 |
16 | PLK3 | 2.02402158 |
17 | NEK2 | 1.98239448 |
18 | ICK | 1.94222344 |
19 | STK16 | 1.91791637 |
20 | TESK2 | 1.89964710 |
21 | DYRK3 | 1.85008778 |
22 | NEK1 | 1.83132585 |
23 | ATR | 1.80658129 |
24 | ERBB3 | 1.77906100 |
25 | MKNK2 | 1.69720409 |
26 | EIF2AK3 | 1.68987154 |
27 | PLK1 | 1.68200248 |
28 | SIK3 | 1.62234450 |
29 | LATS2 | 1.59173231 |
30 | TTK | 1.58626046 |
31 | BRSK1 | 1.56051414 |
32 | PLK4 | 1.55763604 |
33 | VRK1 | 1.55430594 |
34 | BCR | 1.54674199 |
35 | AURKB | 1.48224115 |
36 | FGFR4 | 1.46413379 |
37 | RPS6KB2 | 1.35561854 |
38 | PAK4 | 1.34319141 |
39 | CDK7 | 1.30840689 |
40 | CDK8 | 1.24231762 |
41 | KSR2 | 1.21903636 |
42 | BRD4 | 1.18411613 |
43 | CHEK1 | 1.17117171 |
44 | LATS1 | 1.16929412 |
45 | CHEK2 | 1.15678100 |
46 | RPS6KA4 | 1.13447415 |
47 | SCYL2 | 1.11350787 |
48 | LIMK1 | 1.10269100 |
49 | TESK1 | 1.09796311 |
50 | PKN2 | 1.05526770 |
51 | TLK1 | 1.05321164 |
52 | MAP3K10 | 1.04744024 |
53 | EEF2K | 1.02287700 |
54 | AURKA | 0.94466616 |
55 | FGFR1 | 0.93788432 |
56 | KSR1 | 0.92813706 |
57 | ATM | 0.88375408 |
58 | CDK4 | 0.86479089 |
59 | STK10 | 0.86012809 |
60 | VRK2 | 0.83935774 |
61 | DYRK2 | 0.83726438 |
62 | MAP3K8 | 0.81499016 |
63 | MAP3K14 | 0.80550005 |
64 | YES1 | 0.80316071 |
65 | NEK9 | 0.79296270 |
66 | * CDK2 | 0.78511879 |
67 | PTK6 | 0.78123901 |
68 | TTN | 0.76693849 |
69 | TAF1 | 0.76448486 |
70 | * CDK1 | 0.74154357 |
71 | SIK1 | 0.73765838 |
72 | CLK1 | 0.73152863 |
73 | MAP3K6 | 0.73043980 |
74 | MTOR | 0.69150180 |
75 | RAF1 | 0.64440644 |
76 | RET | 0.63234944 |
77 | CSNK1G3 | 0.61786215 |
78 | MELK | 0.61540209 |
79 | EIF2AK2 | 0.61440961 |
80 | PBK | 0.60698273 |
81 | UHMK1 | 0.60653485 |
82 | PLK2 | 0.59263005 |
83 | MAP2K7 | 0.54920114 |
84 | CSNK2A1 | 0.54847187 |
85 | CSNK2A2 | 0.53846258 |
86 | EPHB1 | 0.53345804 |
87 | TYRO3 | 0.52795270 |
88 | STK4 | 0.52588136 |
89 | CDK6 | 0.52221245 |
90 | CDK9 | 0.49503381 |
91 | ERBB4 | 0.48802732 |
92 | BMX | 0.48140821 |
93 | FGFR2 | 0.45518122 |
94 | CDK12 | 0.44517904 |
95 | NTRK1 | 0.44207598 |
96 | PNCK | 0.43869678 |
97 | RIPK1 | 0.43817525 |
98 | LRRK2 | 0.41922800 |
99 | CSNK1A1L | 0.41676832 |
100 | CDK18 | 0.40975207 |
101 | DYRK1B | 0.40018693 |
102 | PRKDC | 0.39587151 |
103 | PDGFRA | 0.38778967 |
104 | AKT2 | 0.38698861 |
105 | PAK1 | 0.37654084 |
106 | EPHB2 | 0.36676865 |
107 | ILK | 0.36661875 |
108 | CDK14 | 0.36300490 |
109 | RPS6KA5 | 0.36077262 |
110 | CDK3 | 0.36028384 |
111 | WNK3 | 0.35418254 |
112 | EPHA2 | 0.35229506 |
113 | BMPR1B | 0.34394202 |
114 | PRKCI | 0.34310800 |
115 | NEK6 | 0.32167856 |
116 | CDK15 | 0.31019600 |
117 | CSF1R | 0.31006290 |
118 | MAPK9 | 0.30835790 |
119 | MAPK14 | 0.30024435 |
120 | CDK11A | 0.29937925 |
121 | ZAK | 0.29512334 |
122 | RPS6KB1 | 0.29337055 |
123 | BTK | 0.29201143 |
124 | CSNK1G1 | 0.28989041 |
125 | KDR | 0.28241474 |
126 | CHUK | 0.27111711 |
127 | ITK | 0.25759438 |
128 | CDK19 | 0.24517871 |
129 | MAPK13 | 0.24473410 |
130 | PAK2 | 0.24329321 |
131 | ALK | 0.24125076 |
132 | ERBB2 | 0.24061656 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.60196966 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 4.14506434 |
3 | * Spliceosome_Homo sapiens_hsa03040 | 3.74603111 |
4 | Cell cycle_Homo sapiens_hsa04110 | 3.17399501 |
5 | RNA transport_Homo sapiens_hsa03013 | 3.07130275 |
6 | Base excision repair_Homo sapiens_hsa03410 | 2.99442255 |
7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.97228533 |
8 | Proteasome_Homo sapiens_hsa03050 | 2.93644788 |
9 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.88273160 |
10 | Homologous recombination_Homo sapiens_hsa03440 | 2.67948793 |
11 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.53319897 |
12 | RNA polymerase_Homo sapiens_hsa03020 | 2.47409367 |
13 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.34656988 |
14 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.21642931 |
15 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.06350863 |
16 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.00931011 |
17 | RNA degradation_Homo sapiens_hsa03018 | 1.97617778 |
18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.93841273 |
19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.92117408 |
20 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.87120222 |
21 | Ribosome_Homo sapiens_hsa03010 | 1.83408083 |
22 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.54618138 |
23 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.43352904 |
24 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.36503092 |
25 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.35344590 |
26 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.32694961 |
27 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.30710413 |
28 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.20999082 |
29 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.18945406 |
30 | * Viral carcinogenesis_Homo sapiens_hsa05203 | 1.17207498 |
31 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.14543123 |
32 | Carbon metabolism_Homo sapiens_hsa01200 | 1.09999725 |
33 | Purine metabolism_Homo sapiens_hsa00230 | 1.07646380 |
34 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.05822952 |
35 | Colorectal cancer_Homo sapiens_hsa05210 | 1.05591942 |
36 | HTLV-I infection_Homo sapiens_hsa05166 | 1.05527355 |
37 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.01140436 |
38 | Protein export_Homo sapiens_hsa03060 | 1.00618590 |
39 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.97890573 |
40 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.90554845 |
41 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.89584531 |
42 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.88706171 |
43 | Alcoholism_Homo sapiens_hsa05034 | 0.88672146 |
44 | Glioma_Homo sapiens_hsa05214 | 0.88193336 |
45 | * MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.86536634 |
46 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.85765449 |
47 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.84039784 |
48 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.81886951 |
49 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.79175773 |
50 | * Herpes simplex infection_Homo sapiens_hsa05168 | 0.78765179 |
51 | Thyroid cancer_Homo sapiens_hsa05216 | 0.78336428 |
52 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.78283774 |
53 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.77590515 |
54 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.75724417 |
55 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.75332510 |
56 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.75020071 |
57 | Lysine degradation_Homo sapiens_hsa00310 | 0.73927301 |
58 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.73867953 |
59 | Legionellosis_Homo sapiens_hsa05134 | 0.73616017 |
60 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.72563062 |
61 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.71641821 |
62 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.69468295 |
63 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.66901930 |
64 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.65419601 |
65 | Viral myocarditis_Homo sapiens_hsa05416 | 0.64826476 |
66 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.64625106 |
67 | Salmonella infection_Homo sapiens_hsa05132 | 0.62935806 |
68 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.61593581 |
69 | Shigellosis_Homo sapiens_hsa05131 | 0.61052230 |
70 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.60919252 |
71 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.60614992 |
72 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.59859399 |
73 | Prion diseases_Homo sapiens_hsa05020 | 0.59750884 |
74 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.59512292 |
75 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.58754642 |
76 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.58590977 |
77 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.56999611 |
78 | Hepatitis B_Homo sapiens_hsa05161 | 0.53640233 |
79 | Pathways in cancer_Homo sapiens_hsa05200 | 0.53045901 |
80 | Hepatitis C_Homo sapiens_hsa05160 | 0.52080092 |
81 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.51793569 |
82 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.51777190 |
83 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.51011281 |
84 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.50643368 |
85 | Adherens junction_Homo sapiens_hsa04520 | 0.50580970 |
86 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.48440392 |
87 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.47632832 |
88 | Gap junction_Homo sapiens_hsa04540 | 0.47193825 |
89 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.46779160 |
90 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.45223528 |
91 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.43279600 |
92 | Measles_Homo sapiens_hsa05162 | 0.42741827 |
93 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.39114901 |
94 | Endometrial cancer_Homo sapiens_hsa05213 | 0.38922411 |
95 | Prostate cancer_Homo sapiens_hsa05215 | 0.38372765 |
96 | Apoptosis_Homo sapiens_hsa04210 | 0.37452213 |
97 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.37392356 |
98 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.36187705 |
99 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.35784841 |
100 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.34714093 |
101 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.33393364 |
102 | Tight junction_Homo sapiens_hsa04530 | 0.32543850 |
103 | Bladder cancer_Homo sapiens_hsa05219 | 0.32331627 |
104 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.27424909 |
105 | Axon guidance_Homo sapiens_hsa04360 | 0.27155956 |
106 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.27139604 |
107 | Melanoma_Homo sapiens_hsa05218 | 0.27138391 |
108 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.24788331 |
109 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.22799886 |
110 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.22163727 |
111 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.21061381 |
112 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.20763035 |
113 | Influenza A_Homo sapiens_hsa05164 | 0.20300001 |
114 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.20080875 |
115 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.20054585 |
116 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.19829396 |
117 | Focal adhesion_Homo sapiens_hsa04510 | 0.19220416 |
118 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.17881630 |
119 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.17452311 |
120 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.16608062 |
121 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.16565406 |
122 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.13011227 |
123 | Huntingtons disease_Homo sapiens_hsa05016 | 0.12896025 |
124 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.12599097 |
125 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.12079348 |
126 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.11742596 |
127 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.11630820 |
128 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.09634204 |
129 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.08730275 |