

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial calcium ion transport (GO:0006851) | 7.66069453 |
| 2 | pseudouridine synthesis (GO:0001522) | 7.47694274 |
| 3 | vitamin transmembrane transport (GO:0035461) | 7.42219498 |
| 4 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 6.66439353 |
| 5 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 6.59372267 |
| 6 | negative regulation of smooth muscle cell differentiation (GO:0051151) | 6.23069729 |
| 7 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 6.02607912 |
| 8 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 5.92815969 |
| 9 | oligosaccharide catabolic process (GO:0009313) | 5.53463407 |
| 10 | cytokine biosynthetic process (GO:0042089) | 4.98919100 |
| 11 | regulation of mitotic spindle organization (GO:0060236) | 4.84474052 |
| 12 | DNA double-strand break processing (GO:0000729) | 4.78227843 |
| 13 | protein retention in ER lumen (GO:0006621) | 4.66348377 |
| 14 | mitotic metaphase plate congression (GO:0007080) | 4.63134447 |
| 15 | regulation of RIG-I signaling pathway (GO:0039535) | 4.59246624 |
| 16 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.55569739 |
| 17 | NADH dehydrogenase complex assembly (GO:0010257) | 4.55569739 |
| 18 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.55569739 |
| 19 | mitotic sister chromatid segregation (GO:0000070) | 4.44830536 |
| 20 | cellular protein complex localization (GO:0034629) | 4.43549951 |
| 21 | trophectodermal cell differentiation (GO:0001829) | 4.37561218 |
| 22 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 4.30671401 |
| 23 | regulation of DNA damage checkpoint (GO:2000001) | 4.28470223 |
| 24 | negative regulation of Ras GTPase activity (GO:0034261) | 4.27313567 |
| 25 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 4.26418744 |
| 26 | mitotic chromosome condensation (GO:0007076) | 4.15233214 |
| 27 | sister chromatid segregation (GO:0000819) | 4.05033798 |
| 28 | post-embryonic morphogenesis (GO:0009886) | 3.98454421 |
| 29 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 3.98235528 |
| 30 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 3.93654443 |
| 31 | branching involved in prostate gland morphogenesis (GO:0060442) | 3.92949483 |
| 32 | cytokine metabolic process (GO:0042107) | 3.90364751 |
| 33 | mitochondrial calcium ion homeostasis (GO:0051560) | 3.90344860 |
| 34 | protein complex localization (GO:0031503) | 3.89717331 |
| 35 | definitive hemopoiesis (GO:0060216) | 3.86923421 |
| 36 | chemosensory behavior (GO:0007635) | 3.85819140 |
| 37 | DNA replication initiation (GO:0006270) | 3.85215008 |
| 38 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) | 3.82308992 |
| 39 | chromatin assembly (GO:0031497) | 3.79606296 |
| 40 | positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968) | 3.77111602 |
| 41 | ribosomal small subunit assembly (GO:0000028) | 3.76189903 |
| 42 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.70192397 |
| 43 | histone H2A monoubiquitination (GO:0035518) | 3.70083676 |
| 44 | outer ear morphogenesis (GO:0042473) | 3.66090589 |
| 45 | cell morphogenesis involved in neuron differentiation (GO:0048667) | 3.62593007 |
| 46 | base-excision repair, AP site formation (GO:0006285) | 3.58070253 |
| 47 | NIK/NF-kappaB signaling (GO:0038061) | 3.53051730 |
| 48 | metaphase plate congression (GO:0051310) | 3.51042480 |
| 49 | histone H3-K9 methylation (GO:0051567) | 3.40674518 |
| 50 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.38418940 |
| 51 | DNA strand renaturation (GO:0000733) | 3.36015141 |
| 52 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.33081654 |
| 53 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.33081654 |
| 54 | regulation of transcription elongation from RNA polymerase II promoter (GO:0034243) | 3.25991012 |
| 55 | ribosome biogenesis (GO:0042254) | 3.23335334 |
| 56 | histone monoubiquitination (GO:0010390) | 3.22202662 |
| 57 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.19771798 |
| 58 | histone H2B ubiquitination (GO:0033523) | 3.17828652 |
| 59 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.12018652 |
| 60 | chromosome organization involved in meiosis (GO:0070192) | 3.10228345 |
| 61 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.07462699 |
| 62 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.07462699 |
| 63 | DNA strand elongation (GO:0022616) | 3.02696687 |
| 64 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.98277703 |
| 65 | rRNA methylation (GO:0031167) | 2.96307611 |
| 66 | regulation of spindle organization (GO:0090224) | 2.94837761 |
| 67 | positive regulation of histone methylation (GO:0031062) | 2.94113219 |
| 68 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 2.93368618 |
| 69 | negative regulation of GTPase activity (GO:0034260) | 2.92408121 |
| 70 | negative regulation of GTP catabolic process (GO:0033125) | 2.92408121 |
| 71 | positive regulation of microtubule polymerization (GO:0031116) | 2.91938617 |
| 72 | protein maturation by protein folding (GO:0022417) | 2.90756389 |
| 73 | protein complex biogenesis (GO:0070271) | 2.87113363 |
| 74 | cysteine metabolic process (GO:0006534) | 2.84100361 |
| 75 | rRNA modification (GO:0000154) | 2.83802547 |
| 76 | protein localization to kinetochore (GO:0034501) | 2.83070018 |
| 77 | phenylpropanoid metabolic process (GO:0009698) | 2.76402884 |
| 78 | homocysteine metabolic process (GO:0050667) | 2.74618076 |
| 79 | positive regulation of actin cytoskeleton reorganization (GO:2000251) | 2.74127822 |
| 80 | UTP biosynthetic process (GO:0006228) | 2.74081887 |
| 81 | establishment of viral latency (GO:0019043) | 2.72860135 |
| 82 | histone methylation (GO:0016571) | 2.71633211 |
| 83 | mitotic spindle assembly checkpoint (GO:0007094) | 2.70166384 |
| 84 | peptidyl-lysine dimethylation (GO:0018027) | 2.69951321 |
| 85 | negative regulation of interleukin-17 production (GO:0032700) | 2.69924905 |
| 86 | histone H3-K9 modification (GO:0061647) | 2.68873591 |
| 87 | nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) | 2.68773789 |
| 88 | positive regulation of cell cycle checkpoint (GO:1901978) | 2.68687847 |
| 89 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.68349058 |
| 90 | epithelial cell maturation (GO:0002070) | 2.67824290 |
| 91 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 2.66322667 |
| 92 | embryonic process involved in female pregnancy (GO:0060136) | 2.64872096 |
| 93 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.64811762 |
| 94 | spindle assembly checkpoint (GO:0071173) | 2.64631918 |
| 95 | positive regulation of DNA-templated transcription, elongation (GO:0032786) | 2.64172207 |
| 96 | regulation of stem cell maintenance (GO:2000036) | 2.63283545 |
| 97 | positive regulation of glycoprotein biosynthetic process (GO:0010560) | 2.63165029 |
| 98 | DNA unwinding involved in DNA replication (GO:0006268) | 2.60733436 |
| 99 | nuclear envelope reassembly (GO:0031468) | 2.59382022 |
| 100 | mitotic nuclear envelope reassembly (GO:0007084) | 2.59382022 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.63991752 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.65716410 |
| 3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.45893488 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.21161104 |
| 5 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 3.20011980 |
| 6 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 3.19215899 |
| 7 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.10144200 |
| 8 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.72099188 |
| 9 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.67930633 |
| 10 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.67843388 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.67792287 |
| 12 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.57327182 |
| 13 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.43288397 |
| 14 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.27983420 |
| 15 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.23919845 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.19978284 |
| 17 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.18381828 |
| 18 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.08661353 |
| 19 | MYC_22102868_ChIP-Seq_BL_Human | 2.06156248 |
| 20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.05362154 |
| 21 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 2.02204913 |
| 22 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.93215283 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.86464451 |
| 24 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.82371672 |
| 25 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.80961206 |
| 26 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.78449696 |
| 27 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.77791585 |
| 28 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.76843826 |
| 29 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.68852884 |
| 30 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.66798931 |
| 31 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.66746309 |
| 32 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.64075239 |
| 33 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.60304057 |
| 34 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.55668240 |
| 35 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.50923978 |
| 36 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.48720314 |
| 37 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.48482918 |
| 38 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.43440225 |
| 39 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.43115640 |
| 40 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.42841268 |
| 41 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.41779246 |
| 42 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.38092246 |
| 43 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.37892340 |
| 44 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.34762676 |
| 45 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.32789517 |
| 46 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.31314251 |
| 47 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.30991418 |
| 48 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.29860590 |
| 49 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.28584181 |
| 50 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.26617185 |
| 51 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.24944106 |
| 52 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.24687816 |
| 53 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.23481382 |
| 54 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.22871782 |
| 55 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.21764864 |
| 56 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.20427228 |
| 57 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20157287 |
| 58 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.19128974 |
| 59 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.17815395 |
| 60 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.14479368 |
| 61 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.13639251 |
| 62 | P300_27268052_Chip-Seq_Bcells_Human | 1.11310711 |
| 63 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.10942616 |
| 64 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.10717386 |
| 65 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.07810509 |
| 66 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.05260645 |
| 67 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.04232248 |
| 68 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.03255585 |
| 69 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.02716858 |
| 70 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.02461435 |
| 71 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.02107936 |
| 72 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.01482254 |
| 73 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.00868657 |
| 74 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.00332160 |
| 75 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.99128015 |
| 76 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.98571547 |
| 77 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.97787389 |
| 78 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.95587572 |
| 79 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.93921930 |
| 80 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.93492765 |
| 81 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.93326010 |
| 82 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.93175502 |
| 83 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.93032880 |
| 84 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.92698793 |
| 85 | P68_20966046_ChIP-Seq_HELA_Human | 0.91316671 |
| 86 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.90510827 |
| 87 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88785779 |
| 88 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.88140824 |
| 89 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.87005312 |
| 90 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.86339467 |
| 91 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.86049830 |
| 92 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.86047839 |
| 93 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.85410190 |
| 94 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.84245695 |
| 95 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.83906733 |
| 96 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.82070056 |
| 97 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.82035182 |
| 98 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.81845291 |
| 99 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.81299094 |
| 100 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.80764329 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 4.74801671 |
| 2 | MP0000569_abnormal_digit_pigmentation | 4.39757468 |
| 3 | MP0000566_synostosis | 4.33520197 |
| 4 | MP0005451_abnormal_body_composition | 4.05037334 |
| 5 | MP0000015_abnormal_ear_pigmentation | 3.22133283 |
| 6 | MP0005058_abnormal_lysosome_morphology | 2.84450481 |
| 7 | MP0005174_abnormal_tail_pigmentation | 2.80408522 |
| 8 | MP0003567_abnormal_fetal_cardiomyocyte | 2.59777460 |
| 9 | MP0003329_amyloid_beta_deposits | 2.58848046 |
| 10 | MP0009384_cardiac_valve_regurgitation | 2.55231508 |
| 11 | MP0002009_preneoplasia | 2.41745800 |
| 12 | MP0001348_abnormal_lacrimal_gland | 2.34194597 |
| 13 | MP0008057_abnormal_DNA_replication | 2.31295047 |
| 14 | MP0004957_abnormal_blastocyst_morpholog | 2.29755657 |
| 15 | MP0008058_abnormal_DNA_repair | 2.26363580 |
| 16 | MP0000604_amyloidosis | 2.25166964 |
| 17 | MP0003111_abnormal_nucleus_morphology | 2.11921768 |
| 18 | MP0003303_peritoneal_inflammation | 2.06583014 |
| 19 | MP0005360_urolithiasis | 2.05078763 |
| 20 | MP0001851_eye_inflammation | 1.99989689 |
| 21 | MP0001873_stomach_inflammation | 1.86510228 |
| 22 | MP0010094_abnormal_chromosome_stability | 1.84419182 |
| 23 | MP0005464_abnormal_platelet_physiology | 1.82084241 |
| 24 | MP0001730_embryonic_growth_arrest | 1.81389119 |
| 25 | MP0002396_abnormal_hematopoietic_system | 1.80701364 |
| 26 | MP0005387_immune_system_phenotype | 1.71059854 |
| 27 | MP0001790_abnormal_immune_system | 1.71059854 |
| 28 | MP0004808_abnormal_hematopoietic_stem | 1.69857510 |
| 29 | MP0009046_muscle_twitch | 1.60044955 |
| 30 | MP0002653_abnormal_ependyma_morphology | 1.54085256 |
| 31 | MP0006072_abnormal_retinal_apoptosis | 1.38930249 |
| 32 | MP0001545_abnormal_hematopoietic_system | 1.37148247 |
| 33 | MP0005397_hematopoietic_system_phenotyp | 1.37148247 |
| 34 | MP0003943_abnormal_hepatobiliary_system | 1.34140730 |
| 35 | MP0003315_abnormal_perineum_morphology | 1.33715905 |
| 36 | MP0001727_abnormal_embryo_implantation | 1.32594741 |
| 37 | MP0002160_abnormal_reproductive_system | 1.31413022 |
| 38 | MP0005332_abnormal_amino_acid | 1.30069094 |
| 39 | MP0008007_abnormal_cellular_replicative | 1.28055009 |
| 40 | MP0002138_abnormal_hepatobiliary_system | 1.25836018 |
| 41 | MP0000490_abnormal_crypts_of | 1.25494050 |
| 42 | MP0003763_abnormal_thymus_physiology | 1.22649393 |
| 43 | MP0002877_abnormal_melanocyte_morpholog | 1.22251028 |
| 44 | MP0002095_abnormal_skin_pigmentation | 1.21327420 |
| 45 | MP0003077_abnormal_cell_cycle | 1.19523002 |
| 46 | MP0002722_abnormal_immune_system | 1.17324868 |
| 47 | MP0000537_abnormal_urethra_morphology | 1.15878129 |
| 48 | MP0000689_abnormal_spleen_morphology | 1.14093086 |
| 49 | MP0003195_calcinosis | 1.11768215 |
| 50 | MP0009697_abnormal_copulation | 1.11637830 |
| 51 | MP0003718_maternal_effect | 1.07715949 |
| 52 | MP0002405_respiratory_system_inflammati | 1.05486116 |
| 53 | MP0002398_abnormal_bone_marrow | 1.04705845 |
| 54 | MP0000685_abnormal_immune_system | 1.04376327 |
| 55 | MP0002006_tumorigenesis | 1.00850441 |
| 56 | MP0008932_abnormal_embryonic_tissue | 0.98989034 |
| 57 | MP0001340_abnormal_eyelid_morphology | 0.96510538 |
| 58 | MP0000462_abnormal_digestive_system | 0.96103732 |
| 59 | MP0002909_abnormal_adrenal_gland | 0.95812432 |
| 60 | MP0002938_white_spotting | 0.92084871 |
| 61 | MP0000313_abnormal_cell_death | 0.91672228 |
| 62 | MP0004133_heterotaxia | 0.85503114 |
| 63 | MP0002080_prenatal_lethality | 0.84822124 |
| 64 | MP0001299_abnormal_eye_distance/ | 0.83130215 |
| 65 | MP0000350_abnormal_cell_proliferation | 0.82953258 |
| 66 | MP0000653_abnormal_sex_gland | 0.80845411 |
| 67 | MP0003941_abnormal_skin_development | 0.79895739 |
| 68 | MP0006036_abnormal_mitochondrial_physio | 0.75632162 |
| 69 | MP0004185_abnormal_adipocyte_glucose | 0.75166700 |
| 70 | MP0002177_abnormal_outer_ear | 0.73992819 |
| 71 | MP0001145_abnormal_male_reproductive | 0.72565799 |
| 72 | MP0000598_abnormal_liver_morphology | 0.71947947 |
| 73 | MP0002429_abnormal_blood_cell | 0.71460792 |
| 74 | MP0000609_abnormal_liver_physiology | 0.70541276 |
| 75 | MP0000358_abnormal_cell_content/ | 0.70268173 |
| 76 | MP0001672_abnormal_embryogenesis/_devel | 0.69842320 |
| 77 | MP0005380_embryogenesis_phenotype | 0.69842320 |
| 78 | MP0000716_abnormal_immune_system | 0.69760244 |
| 79 | MP0002233_abnormal_nose_morphology | 0.69215220 |
| 80 | MP0005410_abnormal_fertilization | 0.68388314 |
| 81 | MP0005595_abnormal_vascular_smooth | 0.68232586 |
| 82 | MP0008875_abnormal_xenobiotic_pharmacok | 0.67776902 |
| 83 | MP0002166_altered_tumor_susceptibility | 0.66944716 |
| 84 | MP0003632_abnormal_nervous_system | 0.66499471 |
| 85 | MP0001929_abnormal_gametogenesis | 0.66034057 |
| 86 | MP0003984_embryonic_growth_retardation | 0.65516009 |
| 87 | MP0003115_abnormal_respiratory_system | 0.64975942 |
| 88 | MP0009643_abnormal_urine_homeostasis | 0.64468969 |
| 89 | MP0000432_abnormal_head_morphology | 0.64213159 |
| 90 | MP0005084_abnormal_gallbladder_morpholo | 0.63931445 |
| 91 | MP0002086_abnormal_extraembryonic_tissu | 0.63006149 |
| 92 | MP0002210_abnormal_sex_determination | 0.62766162 |
| 93 | MP0005253_abnormal_eye_physiology | 0.62110655 |
| 94 | MP0000013_abnormal_adipose_tissue | 0.61895364 |
| 95 | MP0005381_digestive/alimentary_phenotyp | 0.59591171 |
| 96 | MP0002019_abnormal_tumor_incidence | 0.59525580 |
| 97 | MP0002088_abnormal_embryonic_growth/wei | 0.59481066 |
| 98 | MP0001346_abnormal_lacrimal_gland | 0.57732822 |
| 99 | MP0001915_intracranial_hemorrhage | 0.57484024 |
| 100 | MP0005389_reproductive_system_phenotype | 0.57372482 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 6.45785032 |
| 2 | Reticulocytopenia (HP:0001896) | 6.39810394 |
| 3 | Vacuolated lymphocytes (HP:0001922) | 6.23003395 |
| 4 | Chromsome breakage (HP:0040012) | 5.95786040 |
| 5 | Abnormal biliary tract physiology (HP:0012439) | 5.38554675 |
| 6 | Bile duct proliferation (HP:0001408) | 5.38554675 |
| 7 | Duplicated collecting system (HP:0000081) | 5.13137108 |
| 8 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 4.98738535 |
| 9 | Abnormality of the renal collecting system (HP:0004742) | 4.92613600 |
| 10 | Abnormality of pyrimidine metabolism (HP:0004353) | 4.57704598 |
| 11 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 4.45868790 |
| 12 | Congenital stationary night blindness (HP:0007642) | 4.40888968 |
| 13 | Confusion (HP:0001289) | 4.20278159 |
| 14 | Increased cerebral lipofuscin (HP:0011813) | 4.16116355 |
| 15 | Ectopic kidney (HP:0000086) | 3.87197406 |
| 16 | Duplication of thumb phalanx (HP:0009942) | 3.53763645 |
| 17 | Abnormality of DNA repair (HP:0003254) | 3.42464806 |
| 18 | Global brain atrophy (HP:0002283) | 3.36888245 |
| 19 | Bifid tongue (HP:0010297) | 3.35253046 |
| 20 | Septate vagina (HP:0001153) | 3.30162496 |
| 21 | Failure to thrive in infancy (HP:0001531) | 3.28623664 |
| 22 | Hypercortisolism (HP:0001578) | 3.21914359 |
| 23 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.21763573 |
| 24 | Optic nerve coloboma (HP:0000588) | 3.17225177 |
| 25 | Pancreatic cysts (HP:0001737) | 3.16786667 |
| 26 | Ureteral duplication (HP:0000073) | 3.05883591 |
| 27 | Absent radius (HP:0003974) | 3.04766141 |
| 28 | Abnormality of midbrain morphology (HP:0002418) | 2.87532232 |
| 29 | Molar tooth sign on MRI (HP:0002419) | 2.87532232 |
| 30 | Absent thumb (HP:0009777) | 2.86362801 |
| 31 | Pancreatic fibrosis (HP:0100732) | 2.85407189 |
| 32 | Aplasia involving forearm bones (HP:0009822) | 2.85050040 |
| 33 | Absent forearm bone (HP:0003953) | 2.85050040 |
| 34 | True hermaphroditism (HP:0010459) | 2.83087186 |
| 35 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.80843937 |
| 36 | Asplenia (HP:0001746) | 2.77702169 |
| 37 | Recurrent cutaneous fungal infections (HP:0011370) | 2.77280836 |
| 38 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.77280836 |
| 39 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.68264465 |
| 40 | Abnormal pupillary function (HP:0007686) | 2.64534037 |
| 41 | Mutism (HP:0002300) | 2.63682993 |
| 42 | Clubbing of toes (HP:0100760) | 2.58726326 |
| 43 | Agammaglobulinemia (HP:0004432) | 2.54760199 |
| 44 | Truncal obesity (HP:0001956) | 2.48797176 |
| 45 | Pheochromocytoma (HP:0002666) | 2.47957830 |
| 46 | Epiphyseal dysplasia (HP:0002656) | 2.46578494 |
| 47 | Meckel diverticulum (HP:0002245) | 2.46219344 |
| 48 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.42153431 |
| 49 | Abnormality of the ileum (HP:0001549) | 2.37689845 |
| 50 | Horseshoe kidney (HP:0000085) | 2.33651885 |
| 51 | Abnormality of the preputium (HP:0100587) | 2.33572765 |
| 52 | 11 pairs of ribs (HP:0000878) | 2.29835923 |
| 53 | Pseudobulbar signs (HP:0002200) | 2.29170901 |
| 54 | Impaired smooth pursuit (HP:0007772) | 2.28297458 |
| 55 | Esophageal neoplasm (HP:0100751) | 2.27570516 |
| 56 | Neoplasm of head and neck (HP:0012288) | 2.27570516 |
| 57 | Abnormal number of incisors (HP:0011064) | 2.26712167 |
| 58 | Hypokinesia (HP:0002375) | 2.24436832 |
| 59 | Periodontitis (HP:0000704) | 2.14370816 |
| 60 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.10965130 |
| 61 | Viral hepatitis (HP:0006562) | 2.10163015 |
| 62 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.06436609 |
| 63 | Unilateral renal agenesis (HP:0000122) | 2.04893528 |
| 64 | Acute myeloid leukemia (HP:0004808) | 2.02625614 |
| 65 | Nephronophthisis (HP:0000090) | 2.01220730 |
| 66 | Hypergonadotropic hypogonadism (HP:0000815) | 1.98348936 |
| 67 | Abnormality of chromosome stability (HP:0003220) | 1.97110218 |
| 68 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.95875710 |
| 69 | Absent epiphyses (HP:0010577) | 1.95875710 |
| 70 | Duodenal stenosis (HP:0100867) | 1.92738905 |
| 71 | Small intestinal stenosis (HP:0012848) | 1.92738905 |
| 72 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.92511623 |
| 73 | Paraparesis (HP:0002385) | 1.88721869 |
| 74 | Progressive visual loss (HP:0000529) | 1.87208267 |
| 75 | Neuroendocrine neoplasm (HP:0100634) | 1.85897550 |
| 76 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.85854069 |
| 77 | Abnormality of alanine metabolism (HP:0010916) | 1.85854069 |
| 78 | Hyperalaninemia (HP:0003348) | 1.85854069 |
| 79 | Sclerocornea (HP:0000647) | 1.84906757 |
| 80 | Inability to walk (HP:0002540) | 1.84439678 |
| 81 | Hypoglycemic coma (HP:0001325) | 1.84205394 |
| 82 | Abnormality of carpal bone ossification (HP:0006257) | 1.82196963 |
| 83 | Dysostosis multiplex (HP:0000943) | 1.81054683 |
| 84 | Gastrointestinal inflammation (HP:0004386) | 1.81000268 |
| 85 | Myelodysplasia (HP:0002863) | 1.79460946 |
| 86 | Furrowed tongue (HP:0000221) | 1.78630078 |
| 87 | Capillary hemangiomas (HP:0005306) | 1.78018320 |
| 88 | Meningioma (HP:0002858) | 1.76897754 |
| 89 | Inflammation of the large intestine (HP:0002037) | 1.73956197 |
| 90 | Cerebral hemorrhage (HP:0001342) | 1.73711888 |
| 91 | Partial agenesis of the corpus callosum (HP:0001338) | 1.72676350 |
| 92 | Cystic liver disease (HP:0006706) | 1.71772652 |
| 93 | Abnormality of reticulocytes (HP:0004312) | 1.70938213 |
| 94 | Abnormality of the incisor (HP:0000676) | 1.70134065 |
| 95 | Polycythemia (HP:0001901) | 1.69997272 |
| 96 | Insomnia (HP:0100785) | 1.67931971 |
| 97 | Abnormal lung lobation (HP:0002101) | 1.67396224 |
| 98 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.66781579 |
| 99 | Missing ribs (HP:0000921) | 1.65264152 |
| 100 | Arteriovenous malformation (HP:0100026) | 1.63844729 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 6.87583965 |
| 2 | GRK1 | 5.76465937 |
| 3 | VRK1 | 3.74006606 |
| 4 | TIE1 | 2.93527717 |
| 5 | ADRBK2 | 2.71555004 |
| 6 | BUB1 | 2.54795548 |
| 7 | SMG1 | 2.54185497 |
| 8 | SCYL2 | 2.45548130 |
| 9 | CDK12 | 2.27838061 |
| 10 | TESK2 | 2.27355701 |
| 11 | TLK1 | 2.18141265 |
| 12 | BLK | 2.11755282 |
| 13 | FGFR3 | 2.01363157 |
| 14 | DDR2 | 1.98920159 |
| 15 | EEF2K | 1.95785116 |
| 16 | TAF1 | 1.89632016 |
| 17 | RPS6KB2 | 1.82408574 |
| 18 | CDC7 | 1.74402167 |
| 19 | STK3 | 1.63130093 |
| 20 | CHEK2 | 1.58598658 |
| 21 | ERN1 | 1.53508801 |
| 22 | ZAK | 1.50425016 |
| 23 | CDK6 | 1.46239628 |
| 24 | CCNB1 | 1.45318179 |
| 25 | NEK2 | 1.42800039 |
| 26 | NUAK1 | 1.40123960 |
| 27 | WEE1 | 1.29432603 |
| 28 | AKT2 | 1.20959097 |
| 29 | MAPKAPK5 | 1.20416242 |
| 30 | PBK | 1.19139880 |
| 31 | IRAK3 | 1.18820773 |
| 32 | CDK7 | 1.17341878 |
| 33 | MAP3K8 | 1.12964081 |
| 34 | AURKA | 1.08234118 |
| 35 | MAP3K2 | 1.07159545 |
| 36 | EIF2AK3 | 1.06910319 |
| 37 | EIF2AK2 | 1.02227479 |
| 38 | LATS1 | 1.00915517 |
| 39 | TXK | 1.00869043 |
| 40 | MAP3K14 | 1.00080923 |
| 41 | TYRO3 | 0.99400164 |
| 42 | MAP3K1 | 0.97122540 |
| 43 | PLK4 | 0.91009443 |
| 44 | PDK2 | 0.89309734 |
| 45 | KSR2 | 0.88578484 |
| 46 | CDK9 | 0.82432311 |
| 47 | MUSK | 0.79883575 |
| 48 | TAOK2 | 0.77957615 |
| 49 | DYRK1A | 0.77204510 |
| 50 | DAPK3 | 0.74943955 |
| 51 | CDK4 | 0.71269655 |
| 52 | SYK | 0.71173040 |
| 53 | TBK1 | 0.70399358 |
| 54 | PLK1 | 0.68592643 |
| 55 | ATR | 0.66247217 |
| 56 | TAOK1 | 0.64335621 |
| 57 | CHEK1 | 0.59179737 |
| 58 | MAP3K11 | 0.57634560 |
| 59 | STK38 | 0.57358469 |
| 60 | MAP3K3 | 0.51202729 |
| 61 | CSNK1G3 | 0.50406231 |
| 62 | NTRK3 | 0.49524344 |
| 63 | BRD4 | 0.48906262 |
| 64 | MAPK12 | 0.46836541 |
| 65 | GRK6 | 0.45195999 |
| 66 | ABL2 | 0.44961531 |
| 67 | RPS6KA5 | 0.41775864 |
| 68 | RPS6KC1 | 0.41288572 |
| 69 | RPS6KL1 | 0.41288572 |
| 70 | BMPR1B | 0.40758713 |
| 71 | RPS6KA6 | 0.40677133 |
| 72 | CDK2 | 0.39745184 |
| 73 | YES1 | 0.39193869 |
| 74 | MAP4K2 | 0.38592433 |
| 75 | PASK | 0.36637784 |
| 76 | MAP3K4 | 0.36077050 |
| 77 | MAPKAPK3 | 0.36054068 |
| 78 | CDK1 | 0.34396758 |
| 79 | CDK8 | 0.33359299 |
| 80 | HIPK2 | 0.33264549 |
| 81 | CSNK1A1L | 0.32299839 |
| 82 | DYRK3 | 0.31801465 |
| 83 | DAPK1 | 0.31070356 |
| 84 | NME2 | 0.30877307 |
| 85 | PTK2B | 0.30334205 |
| 86 | MAP2K2 | 0.29625712 |
| 87 | MAPK7 | 0.28944120 |
| 88 | LIMK1 | 0.28045403 |
| 89 | CSNK1A1 | 0.26496580 |
| 90 | PDGFRB | 0.26102708 |
| 91 | MAP2K1 | 0.24980425 |
| 92 | PIM1 | 0.24805893 |
| 93 | CSNK1G1 | 0.23001854 |
| 94 | PAK1 | 0.22930830 |
| 95 | FES | 0.22526295 |
| 96 | ATM | 0.22402035 |
| 97 | INSR | 0.22155371 |
| 98 | AURKB | 0.21468175 |
| 99 | PDGFRA | 0.21227833 |
| 100 | MAPK4 | 0.20757554 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 5.25817779 |
| 2 | Other glycan degradation_Homo sapiens_hsa00511 | 4.64479281 |
| 3 | DNA replication_Homo sapiens_hsa03030 | 3.64759801 |
| 4 | Sulfur relay system_Homo sapiens_hsa04122 | 3.49688220 |
| 5 | Alcoholism_Homo sapiens_hsa05034 | 3.43917789 |
| 6 | Base excision repair_Homo sapiens_hsa03410 | 2.91376983 |
| 7 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.70989590 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.48651864 |
| 9 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.32685550 |
| 10 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.29608218 |
| 11 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.29093626 |
| 12 | Arginine biosynthesis_Homo sapiens_hsa00220 | 2.12608860 |
| 13 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 2.04866828 |
| 14 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.99121170 |
| 15 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.95524041 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 1.95358033 |
| 17 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.95016338 |
| 18 | Cell cycle_Homo sapiens_hsa04110 | 1.92768628 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.65979305 |
| 20 | Mismatch repair_Homo sapiens_hsa03430 | 1.60517954 |
| 21 | Lysine degradation_Homo sapiens_hsa00310 | 1.51315384 |
| 22 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.48660627 |
| 23 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.46421013 |
| 24 | Phototransduction_Homo sapiens_hsa04744 | 1.45985745 |
| 25 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.34540768 |
| 26 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.24335794 |
| 27 | RNA transport_Homo sapiens_hsa03013 | 1.21560650 |
| 28 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.21454922 |
| 29 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.20055783 |
| 30 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.17271287 |
| 31 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.17253280 |
| 32 | Ribosome_Homo sapiens_hsa03010 | 1.12475812 |
| 33 | Bladder cancer_Homo sapiens_hsa05219 | 1.08410378 |
| 34 | Basal transcription factors_Homo sapiens_hsa03022 | 1.08055763 |
| 35 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.06264137 |
| 36 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.06262920 |
| 37 | RNA polymerase_Homo sapiens_hsa03020 | 1.03601589 |
| 38 | Prion diseases_Homo sapiens_hsa05020 | 1.00941668 |
| 39 | Platelet activation_Homo sapiens_hsa04611 | 1.00724111 |
| 40 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.96728692 |
| 41 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.94800624 |
| 42 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.89935426 |
| 43 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.87889170 |
| 44 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.83468245 |
| 45 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.77187460 |
| 46 | Lysosome_Homo sapiens_hsa04142 | 0.74339338 |
| 47 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.73494573 |
| 48 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.71689918 |
| 49 | Purine metabolism_Homo sapiens_hsa00230 | 0.70968285 |
| 50 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.70360488 |
| 51 | Thyroid cancer_Homo sapiens_hsa05216 | 0.69161694 |
| 52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.68587155 |
| 53 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.68527955 |
| 54 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.68266084 |
| 55 | Huntingtons disease_Homo sapiens_hsa05016 | 0.64489604 |
| 56 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.64206180 |
| 57 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.63473546 |
| 58 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.60954813 |
| 59 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.60906637 |
| 60 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.59304757 |
| 61 | Parkinsons disease_Homo sapiens_hsa05012 | 0.58379148 |
| 62 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.56127557 |
| 63 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.56052136 |
| 64 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.55218219 |
| 65 | Carbon metabolism_Homo sapiens_hsa01200 | 0.53461559 |
| 66 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.49345967 |
| 67 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.47928537 |
| 68 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.46414294 |
| 69 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.45725756 |
| 70 | HTLV-I infection_Homo sapiens_hsa05166 | 0.45004328 |
| 71 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.41113072 |
| 72 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.38785889 |
| 73 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.35630880 |
| 74 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.34809270 |
| 75 | Taste transduction_Homo sapiens_hsa04742 | 0.33788448 |
| 76 | Proteasome_Homo sapiens_hsa03050 | 0.33084227 |
| 77 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.32995877 |
| 78 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.32573327 |
| 79 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.32512747 |
| 80 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.31454999 |
| 81 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.29775845 |
| 82 | Metabolic pathways_Homo sapiens_hsa01100 | 0.28714023 |
| 83 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.28388481 |
| 84 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.28131609 |
| 85 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.27655264 |
| 86 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.27513576 |
| 87 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.25482687 |
| 88 | Hepatitis C_Homo sapiens_hsa05160 | 0.23641442 |
| 89 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.22712002 |
| 90 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.21104929 |
| 91 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.20215503 |
| 92 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.17504315 |
| 93 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.17256025 |
| 94 | Alzheimers disease_Homo sapiens_hsa05010 | 0.17188344 |
| 95 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.16415039 |
| 96 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.15561880 |
| 97 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.12588934 |
| 98 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.12375267 |
| 99 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.11966437 |
| 100 | Olfactory transduction_Homo sapiens_hsa04740 | 0.11961674 |

