HNRNPUL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus early-1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by early-1B-55kDa in adenovirus-infected cells. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)4.58559107
2positive regulation of histone deacetylation (GO:0031065)4.27485642
3nuclear pore organization (GO:0006999)4.12588334
4mitotic sister chromatid cohesion (GO:0007064)4.11322032
5regulation of histone H3-K27 methylation (GO:0061085)3.91122858
6heterochromatin organization (GO:0070828)3.86836716
7RNA stabilization (GO:0043489)3.78658756
8mRNA stabilization (GO:0048255)3.78658756
9regulation of histone H3-K9 methylation (GO:0051570)3.75370526
10regulation of mammary gland epithelial cell proliferation (GO:0033599)3.75189994
11DNA unwinding involved in DNA replication (GO:0006268)3.72649376
12dosage compensation (GO:0007549)3.68622685
13Golgi transport vesicle coating (GO:0048200)3.56616558
14COPI coating of Golgi vesicle (GO:0048205)3.56616558
15chromatin assembly (GO:0031497)3.56601232
16negative regulation of histone methylation (GO:0031061)3.55698162
17pre-miRNA processing (GO:0031054)3.49537595
18planar cell polarity pathway involved in neural tube closure (GO:0090179)3.46281537
19adherens junction assembly (GO:0034333)3.44755180
20pore complex assembly (GO:0046931)3.44495160
21cytoplasmic mRNA processing body assembly (GO:0033962)3.41291973
22sister chromatid segregation (GO:0000819)3.40705723
23nucleosome disassembly (GO:0006337)3.39812191
24protein-DNA complex disassembly (GO:0032986)3.39812191
25regulation of RNA export from nucleus (GO:0046831)3.39402409
26protein localization to kinetochore (GO:0034501)3.38048926
27focal adhesion assembly (GO:0048041)3.36592157
28cell-substrate adherens junction assembly (GO:0007045)3.36592157
29glucocorticoid receptor signaling pathway (GO:0042921)3.27758826
30peptidyl-lysine dimethylation (GO:0018027)3.23811142
31germ cell migration (GO:0008354)3.22258962
32regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.21245340
33embryonic process involved in female pregnancy (GO:0060136)3.19601524
34regulation of glucose import in response to insulin stimulus (GO:2001273)3.15234287
35mitotic chromosome condensation (GO:0007076)3.11201846
36activation of Rac GTPase activity (GO:0032863)3.10311084
37protein localization to chromosome, centromeric region (GO:0071459)3.09246962
38positive regulation of protein deacetylation (GO:0090312)3.08773468
39cellular response to epidermal growth factor stimulus (GO:0071364)3.03829326
40positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.02247489
41positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.02247489
42positive regulation of mitotic sister chromatid separation (GO:1901970)3.02247489
43regulation of translational fidelity (GO:0006450)3.02024143
44NLS-bearing protein import into nucleus (GO:0006607)2.97612926
45mitotic sister chromatid segregation (GO:0000070)2.97260814
46response to UV-C (GO:0010225)2.95544052
473-UTR-mediated mRNA stabilization (GO:0070935)2.93471683
48regulation of DNA endoreduplication (GO:0032875)2.92865203
49regulation of early endosome to late endosome transport (GO:2000641)2.91330615
50negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.90982706
51gene silencing by RNA (GO:0031047)2.90916742
52regulation of mRNA stability (GO:0043488)2.90413134
53positive regulation of gene expression, epigenetic (GO:0045815)2.88743553
54intracellular estrogen receptor signaling pathway (GO:0030520)2.87609095
55DNA duplex unwinding (GO:0032508)2.87421393
56gene silencing (GO:0016458)2.87136259
57protein retention in ER lumen (GO:0006621)2.85761318
58DNA geometric change (GO:0032392)2.84323936
59maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.84246312
60mitotic nuclear envelope disassembly (GO:0007077)2.83306739
61positive regulation of SMAD protein import into nucleus (GO:0060391)2.82808287
62protein localization to endosome (GO:0036010)2.82725562
63positive regulation of chromosome segregation (GO:0051984)2.81245346
64protein export from nucleus (GO:0006611)2.80830417
65negative regulation of RNA splicing (GO:0033119)2.78917312
66response to laminar fluid shear stress (GO:0034616)2.77269303
67positive regulation of gamma-delta T cell activation (GO:0046645)2.75202478
68regulation of gamma-delta T cell differentiation (GO:0045586)2.74557056
69regulation of nucleobase-containing compound transport (GO:0032239)2.74166673
70cell-substrate junction assembly (GO:0007044)2.73131938
71translesion synthesis (GO:0019985)2.72811516
72modulation by virus of host process (GO:0019054)2.72595873
73regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.72506891
74pentose-phosphate shunt (GO:0006098)2.71767753
75response to epidermal growth factor (GO:0070849)2.71475620
76regulation of RNA stability (GO:0043487)2.70633826
77corticosteroid receptor signaling pathway (GO:0031958)2.70219166
78positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.69484029
79positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.68584977
80negative regulation of mRNA metabolic process (GO:1903312)2.67996113
81positive thymic T cell selection (GO:0045059)2.66635832
82nuclear envelope disassembly (GO:0051081)2.66318254
83membrane disassembly (GO:0030397)2.66318254
84negative regulation of cell size (GO:0045792)2.65215535
85modulation by symbiont of host cellular process (GO:0044068)2.64529391
86positive regulation of RNA splicing (GO:0033120)2.64150953
87positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.64138786
88retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.63759829
89chromatin silencing (GO:0006342)2.63707821
90trophectodermal cell differentiation (GO:0001829)2.60709031
91embryonic eye morphogenesis (GO:0048048)2.60444726
92cytoskeletal anchoring at plasma membrane (GO:0007016)2.59520089
93regulation of sister chromatid cohesion (GO:0007063)2.58994470
94antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.58448311
95antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.58448311
96chromosome condensation (GO:0030261)2.56245251
97negative regulation of gene expression, epigenetic (GO:0045814)2.55948042
98maternal placenta development (GO:0001893)2.55899897
99negative regulation of mRNA processing (GO:0050686)2.55633946
100regulation of NFAT protein import into nucleus (GO:0051532)2.54260475
101cellular protein complex localization (GO:0034629)2.53974036
102positive regulation by host of viral transcription (GO:0043923)2.53077684
103negative regulation of histone modification (GO:0031057)2.52972078
104regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.52767653
105natural killer cell differentiation (GO:0001779)2.52026507
106negative regulation of fatty acid transport (GO:2000192)2.51699052
107spliceosomal tri-snRNP complex assembly (GO:0000244)2.50797644
108thymic T cell selection (GO:0045061)2.50600956
109G1 DNA damage checkpoint (GO:0044783)2.50116766
110histone H3-K36 demethylation (GO:0070544)2.49897135
111positive regulation of blood vessel endothelial cell migration (GO:0043536)2.49748946
112histone H3-K9 demethylation (GO:0033169)2.49241653
113protein localization to chromosome (GO:0034502)2.48693299
114embryonic camera-type eye morphogenesis (GO:0048596)2.48620940
115alternative mRNA splicing, via spliceosome (GO:0000380)2.48512219
116mitotic G1 DNA damage checkpoint (GO:0031571)2.48243275
117modulation by virus of host morphology or physiology (GO:0019048)2.47369290
118negative regulation of erythrocyte differentiation (GO:0045647)2.47017581
119protein localization to microtubule (GO:0035372)2.45856230
120negative regulation of phagocytosis (GO:0050765)2.45132432
121negative regulation of striated muscle cell differentiation (GO:0051154)2.44762287
122peptidyl-arginine omega-N-methylation (GO:0035247)2.44049644
123epithelial cell differentiation involved in prostate gland development (GO:0060742)2.43569841
124proline biosynthetic process (GO:0006561)2.43289778
125regulation of SMAD protein import into nucleus (GO:0060390)2.42550817
126positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.41942868
127negative regulation of myotube differentiation (GO:0010832)2.41734126
128DNA conformation change (GO:0071103)2.41577747
129protein complex localization (GO:0031503)2.40970889
130cellular response to virus (GO:0098586)2.40504773
131regulation of gamma-delta T cell activation (GO:0046643)2.39521596
132mannose metabolic process (GO:0006013)2.39319941
133regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.39106935
134positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.39106935
135regulation of stem cell maintenance (GO:2000036)2.38882114
136positive regulation of DNA-dependent DNA replication (GO:2000105)2.38813869
137regulation of histone deacetylation (GO:0031063)2.38639445
138histone H3-K9 methylation (GO:0051567)2.38391778
139regulation of chromatin binding (GO:0035561)2.37575088
140stress fiber assembly (GO:0043149)2.37533659
141apoptotic process involved in morphogenesis (GO:0060561)2.37241781
142cellular hyperosmotic response (GO:0071474)2.36954639
143histone H3-K4 methylation (GO:0051568)2.36759742
144basement membrane organization (GO:0071711)2.35992249
145DNA topological change (GO:0006265)2.35901625
146stress granule assembly (GO:0034063)2.35835627
147histone lysine demethylation (GO:0070076)2.35065242
148formation of translation preinitiation complex (GO:0001731)2.34987270
149negative regulation of chromatin modification (GO:1903309)2.33849748
150positive regulation of keratinocyte differentiation (GO:0045618)2.33587005
151DNA replication initiation (GO:0006270)2.33289966
152antigen processing and presentation of endogenous antigen (GO:0019883)2.33091272
153DNA packaging (GO:0006323)2.32591852
154negative regulation of granulocyte differentiation (GO:0030853)2.30006039
155DNA replication-dependent nucleosome assembly (GO:0006335)2.29054108
156DNA replication-dependent nucleosome organization (GO:0034723)2.29054108
157negative regulation of DNA repair (GO:0045738)2.28807270

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.33136539
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.36228694
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.32379322
4MYC_22102868_ChIP-Seq_BL_Human4.15828374
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.67200542
6VDR_21846776_ChIP-Seq_THP-1_Human2.88236882
7TCF7_22412390_ChIP-Seq_EML_Mouse2.67361696
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.67302298
9KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.32608381
10STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.32097140
11* KDM2B_26808549_Chip-Seq_DND41_Human2.28894395
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.27568894
13* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.24587341
14KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.18010467
15TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.10117248
16STAT6_21828071_ChIP-Seq_BEAS2B_Human2.05016879
17* UTX_26944678_Chip-Seq_JUKART_Human2.01659801
18MAF_26560356_Chip-Seq_TH1_Human2.01209855
19KDM2B_26808549_Chip-Seq_SUP-B15_Human1.98547346
20STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.89879191
21FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.86123379
22SCL_19346495_ChIP-Seq_HPC-7_Human1.84091523
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.79796428
24* ELK3_25401928_ChIP-Seq_HUVEC_Human1.79197847
25THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.76866740
26MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.74517749
27RARG_19884340_ChIP-ChIP_MEFs_Mouse1.71723749
28VDR_24763502_ChIP-Seq_THP-1_Human1.70665683
29E2F1_21310950_ChIP-Seq_MCF-7_Human1.68354704
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.67138416
31MYB_26560356_Chip-Seq_TH1_Human1.62151587
32KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.61290022
33BRD4_27068464_Chip-Seq_AML-cells_Mouse1.61126259
34TP63_17297297_ChIP-ChIP_HaCaT_Human1.60963792
35MYC_18555785_ChIP-Seq_MESCs_Mouse1.60196628
36EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.59614586
37* MYB_26560356_Chip-Seq_TH2_Human1.57830046
38KDM2B_26808549_Chip-Seq_JURKAT_Human1.55925520
39TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.49828403
40* CIITA_25753668_ChIP-Seq_RAJI_Human1.48435285
41* TP63_19390658_ChIP-ChIP_HaCaT_Human1.46581968
42* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.46571841
43NCOR1_26117541_ChIP-Seq_K562_Human1.45864949
44ZFP281_27345836_Chip-Seq_ESCs_Mouse1.45661740
45* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.44415666
46* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.41435782
47MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.40845094
48E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.38359601
49SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.37882218
50MYB_21317192_ChIP-Seq_ERMYB_Mouse1.36022701
51DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.35719311
52KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.34399636
53P300_27058665_Chip-Seq_ZR-75-30cells_Human1.34304604
54* RUNX1_22412390_ChIP-Seq_EML_Mouse1.31563118
55* XRN2_22483619_ChIP-Seq_HELA_Human1.31061382
56TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.30748212
57ZFX_18555785_ChIP-Seq_MESCs_Mouse1.30122274
58TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.29905372
59STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.29289744
60* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.28088571
61AR_21909140_ChIP-Seq_LNCAP_Human1.26355482
62KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.25106099
63MAF_26560356_Chip-Seq_TH2_Human1.24612674
64EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.24487494
65SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.23978514
66ZNF263_19887448_ChIP-Seq_K562_Human1.22785118
67* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.22328603
68EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.21415798
69UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.21370129
70ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.20396475
71* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.20115587
72ZFP281_18757296_ChIP-ChIP_E14_Mouse1.17629877
73P68_20966046_ChIP-Seq_HELA_Human1.17220619
74TET1_21451524_ChIP-Seq_MESCs_Mouse1.17163462
75CLOCK_20551151_ChIP-Seq_293T_Human1.16975301
76PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.16428237
77RACK7_27058665_Chip-Seq_MCF-7_Human1.15619978
78TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.14175063
79NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.13914509
80CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.13652822
81* PKCTHETA_26484144_Chip-Seq_BREAST_Human1.12753559
82RUNX_20019798_ChIP-Seq_JUKART_Human1.11549217
83* SA1_27219007_Chip-Seq_ERYTHROID_Human1.11339388
84CHD1_26751641_Chip-Seq_LNCaP_Human1.10649901
85* SPI1_23127762_ChIP-Seq_K562_Human1.10116582
86FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.09977583
87DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.09459484
88HIF1A_21447827_ChIP-Seq_MCF-7_Human1.08870716
89LXR_22292898_ChIP-Seq_THP-1_Human1.08478762
90* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.05256699
91MYC_19030024_ChIP-ChIP_MESCs_Mouse1.04891098
92POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.04881091
93MYC_18358816_ChIP-ChIP_MESCs_Mouse1.04637809
94TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.04517700
95SMC4_20622854_ChIP-Seq_HELA_Human1.04296813
96NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.03046023
97NFIB_24661679_ChIP-Seq_LUNG_Mouse1.02974404
98* KDM5A_27292631_Chip-Seq_BREAST_Human1.01640418
99ATF3_27146783_Chip-Seq_COLON_Human1.01385395
100ESR2_21235772_ChIP-Seq_MCF-7_Human1.00960966
101KDM2B_26808549_Chip-Seq_K562_Human1.00408402
102SRY_22984422_ChIP-ChIP_TESTIS_Rat1.00333875
103ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.00284389
104ESR1_15608294_ChIP-ChIP_MCF-7_Human0.99788591
105ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.99654115
106EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.99346254
107CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.98816838
108SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.98273069
109WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.96802903
110HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.96255572
111NANOG_21062744_ChIP-ChIP_HESCs_Human0.95955764
112SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.95720149
113NANOG_18555785_ChIP-Seq_MESCs_Mouse0.95592101
114SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.95366038
115MYCN_18555785_ChIP-Seq_MESCs_Mouse0.95137072
116* GATA6_25053715_ChIP-Seq_YYC3_Human0.95108940
117IRF8_22096565_ChIP-ChIP_GC-B_Human0.94971469
118GATA1_19941826_ChIP-Seq_K562_Human0.94954733
119RUNX1_27514584_Chip-Seq_MCF-7_Human0.92859357
120TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.92694742
121NELFA_20434984_ChIP-Seq_ESCs_Mouse0.92681628
122* TP53_22127205_ChIP-Seq_IMR90_Human0.92010030
123GATA1_22383799_ChIP-Seq_G1ME_Mouse0.91309704
124* CREB1_26743006_Chip-Seq_LNCaP_Human0.90229867
125MYC_19079543_ChIP-ChIP_MESCs_Mouse0.90106321
126* UBF1/2_26484160_Chip-Seq_HMECs_Human0.89008357
127KLF4_18555785_ChIP-Seq_MESCs_Mouse0.88929749
128STAT3_1855785_ChIP-Seq_MESCs_Mouse0.88576028
129FOXO3_23340844_ChIP-Seq_DLD1_Human0.87362454
130NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.85621598
131VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.84287470
132SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.83726220

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.26015420
2MP0005076_abnormal_cell_differentiation3.24761491
3MP0010352_gastrointestinal_tract_polyps2.94196694
4MP0003300_gastrointestinal_ulcer2.87510558
5MP0009278_abnormal_bone_marrow2.66131658
6MP0010307_abnormal_tumor_latency2.25067523
7MP0004808_abnormal_hematopoietic_stem2.22527074
8MP0003111_abnormal_nucleus_morphology2.09163295
9MP0003303_peritoneal_inflammation2.07812607
10MP0005451_abnormal_body_composition2.06514170
11MP0002396_abnormal_hematopoietic_system2.01945942
12MP0010094_abnormal_chromosome_stability1.94889071
13MP0003566_abnormal_cell_adhesion1.93641320
14MP0005409_darkened_coat_color1.88759015
15MP0003077_abnormal_cell_cycle1.82980875
16MP0008057_abnormal_DNA_replication1.77059940
17MP0001545_abnormal_hematopoietic_system1.73674294
18MP0005397_hematopoietic_system_phenotyp1.73674294
19MP0004858_abnormal_nervous_system1.68906652
20MP0002166_altered_tumor_susceptibility1.68029508
21MP0002796_impaired_skin_barrier1.66412968
22MP0004197_abnormal_fetal_growth/weight/1.63087907
23MP0002249_abnormal_larynx_morphology1.59915136
24MP0000733_abnormal_muscle_development1.59710708
25MP0000350_abnormal_cell_proliferation1.56622975
26MP0001730_embryonic_growth_arrest1.55624932
27MP0001348_abnormal_lacrimal_gland1.54837114
28MP0002877_abnormal_melanocyte_morpholog1.51515309
29MP0000569_abnormal_digit_pigmentation1.49237874
30MP0010234_abnormal_vibrissa_follicle1.48423430
31MP0008877_abnormal_DNA_methylation1.48154598
32MP0004233_abnormal_muscle_weight1.46207800
33MP0000678_abnormal_parathyroid_gland1.45906461
34MP0000703_abnormal_thymus_morphology1.45720711
35MP0006054_spinal_hemorrhage1.45459755
36MP0005501_abnormal_skin_physiology1.44952464
37MP0001849_ear_inflammation1.43256984
38MP0003984_embryonic_growth_retardation1.41364628
39MP0002088_abnormal_embryonic_growth/wei1.40326274
40MP0002086_abnormal_extraembryonic_tissu1.39346591
41MP0005380_embryogenesis_phenotype1.37793405
42MP0001672_abnormal_embryogenesis/_devel1.37793405
43MP0002398_abnormal_bone_marrow1.36201647
44MP0004264_abnormal_extraembryonic_tissu1.35479092
45MP0004957_abnormal_blastocyst_morpholog1.33034965
46MP0002084_abnormal_developmental_patter1.31888529
47MP0003763_abnormal_thymus_physiology1.31529639
48MP0001915_intracranial_hemorrhage1.30966762
49MP0008007_abnormal_cellular_replicative1.29828888
50MP0005623_abnormal_meninges_morphology1.28976319
51MP0009053_abnormal_anal_canal1.28637981
52MP0000685_abnormal_immune_system1.27317032
53MP0005023_abnormal_wound_healing1.26145256
54MP0001697_abnormal_embryo_size1.22486404
55MP0002085_abnormal_embryonic_tissue1.22095043
56MP0004185_abnormal_adipocyte_glucose1.21186648
57MP0000003_abnormal_adipose_tissue1.20402516
58MP0003693_abnormal_embryo_hatching1.20241069
59MP0008961_abnormal_basal_metabolism1.20220106
60MP0005257_abnormal_intraocular_pressure1.20169577
61MP0005621_abnormal_cell_physiology1.18187595
62MP0002722_abnormal_immune_system1.16226515
63MP0002060_abnormal_skin_morphology1.16079088
64MP0003115_abnormal_respiratory_system1.14875447
65MP0002925_abnormal_cardiovascular_devel1.14432024
66MP0002006_tumorigenesis1.13440187
67MP0008260_abnormal_autophagy1.13431970
68MP0001800_abnormal_humoral_immune1.13271524
69MP0000490_abnormal_crypts_of1.10291615
70MP0009703_decreased_birth_body1.09627284
71MP0002080_prenatal_lethality1.09608151
72MP0008438_abnormal_cutaneous_collagen1.08633239
73MP0008932_abnormal_embryonic_tissue1.08238945
74MP0002089_abnormal_postnatal_growth/wei1.08089192
75MP0000689_abnormal_spleen_morphology1.07528316
76MP0000428_abnormal_craniofacial_morphol1.06977725
77MP0003091_abnormal_cell_migration1.06832774
78MP0002019_abnormal_tumor_incidence1.06728700
79MP0001346_abnormal_lacrimal_gland1.06162212
80MP0005058_abnormal_lysosome_morphology1.05523826
81MP0003567_abnormal_fetal_cardiomyocyte1.03741923
82MP0009672_abnormal_birth_weight1.00124204
83MP0004947_skin_inflammation0.99494914
84MP0010630_abnormal_cardiac_muscle0.99005132
85MP0000537_abnormal_urethra_morphology0.97154275
86MP0003045_fibrosis0.95793228
87MP0002697_abnormal_eye_size0.95636930
88MP0002092_abnormal_eye_morphology0.95587755
89MP0003453_abnormal_keratinocyte_physiol0.95202419
90MP0001873_stomach_inflammation0.94843897
91MP0003121_genomic_imprinting0.94728395
92MP0000716_abnormal_immune_system0.94722303
93MP0002452_abnormal_antigen_presenting0.92212406
94MP0009931_abnormal_skin_appearance0.90637869
95MP0000566_synostosis0.90469560
96MP0002429_abnormal_blood_cell0.90046838
97MP0009333_abnormal_splenocyte_physiolog0.90013863
98MP0000313_abnormal_cell_death0.89729962
99MP0003935_abnormal_craniofacial_develop0.89675208
100MP0004272_abnormal_basement_membrane0.89300356
101MP0002405_respiratory_system_inflammati0.89173006
102MP0003448_altered_tumor_morphology0.88161500
103MP0000465_gastrointestinal_hemorrhage0.87100154
104MP0003436_decreased_susceptibility_to0.86975551
105MP0001216_abnormal_epidermal_layer0.86892675
106MP0000266_abnormal_heart_morphology0.86669315
107MP0003942_abnormal_urinary_system0.84957854
108MP0002420_abnormal_adaptive_immunity0.84789461
109MP0001784_abnormal_fluid_regulation0.83912093
110MP0000534_abnormal_ureter_morphology0.83687172
111MP0001790_abnormal_immune_system0.83099688
112MP0005387_immune_system_phenotype0.83099688
113MP0001819_abnormal_immune_cell0.83010770
114MP0010155_abnormal_intestine_physiology0.82700035
115MP0010030_abnormal_orbit_morphology0.82495848
116MP0000858_altered_metastatic_potential0.82113485
117MP0005666_abnormal_adipose_tissue0.82111009
118MP0002009_preneoplasia0.81348630
119MP0004381_abnormal_hair_follicle0.80998271
120MP0005375_adipose_tissue_phenotype0.80911951
121MP0000477_abnormal_intestine_morphology0.79906612
122MP0005464_abnormal_platelet_physiology0.79694730
123MP0005384_cellular_phenotype0.79237323
124MP0000759_abnormal_skeletal_muscle0.78761419
125MP0002098_abnormal_vibrissa_morphology0.78489120
126MP0003279_aneurysm0.77697726
127MP0001293_anophthalmia0.76813829
128MP0008770_decreased_survivor_rate0.76103361
129MP0000432_abnormal_head_morphology0.75330295
130MP0003123_paternal_imprinting0.75147382
131MP0000377_abnormal_hair_follicle0.74508412
132MP0004782_abnormal_surfactant_physiolog0.74480863
133MP0000767_abnormal_smooth_muscle0.73926675
134MP0002970_abnormal_white_adipose0.73690548
135MP0004087_abnormal_muscle_fiber0.73624845

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)3.54728059
2Hyperacusis (HP:0010780)3.24300969
3Broad face (HP:0000283)3.18000641
4Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.98865665
5Short 4th metacarpal (HP:0010044)2.98865665
6Cerebral aneurysm (HP:0004944)2.92127288
7Long eyelashes (HP:0000527)2.74738783
8Obstructive sleep apnea (HP:0002870)2.71625556
9Volvulus (HP:0002580)2.70545260
10Macroorchidism (HP:0000053)2.67132892
11Cellulitis (HP:0100658)2.67023997
12Increased nuchal translucency (HP:0010880)2.64759370
13Increased density of long bones (HP:0006392)2.60055227
14Abnormality of the distal phalanx of the thumb (HP:0009617)2.57312711
15Shallow orbits (HP:0000586)2.51138186
16Distal lower limb amyotrophy (HP:0008944)2.49565914
17Papilloma (HP:0012740)2.46490359
18Verrucae (HP:0200043)2.46490359
19Flat acetabular roof (HP:0003180)2.41523415
20Renovascular hypertension (HP:0100817)2.40931637
21Long palpebral fissure (HP:0000637)2.38150058
22Ulnar bowing (HP:0003031)2.32493708
23Abnormality of the 4th metacarpal (HP:0010012)2.30095658
24Renal duplication (HP:0000075)2.29743689
25Rectal prolapse (HP:0002035)2.27559411
26Premature rupture of membranes (HP:0001788)2.25076272
27High pitched voice (HP:0001620)2.24429797
28Subacute progressive viral hepatitis (HP:0006572)2.20599643
29Heterotopia (HP:0002282)2.20515933
30Elfin facies (HP:0004428)2.15969568
31Deviation of the thumb (HP:0009603)2.14789920
32Centrally nucleated skeletal muscle fibers (HP:0003687)2.12834856
33Nasal polyposis (HP:0100582)2.10752877
34Dysmetric saccades (HP:0000641)2.09314196
35Aortic aneurysm (HP:0004942)2.08713917
36Patellar dislocation (HP:0002999)2.08032331
37Mitral valve prolapse (HP:0001634)2.07835241
38Proximal placement of thumb (HP:0009623)2.06856668
39Abnormality of the phalanges of the hallux (HP:0010057)2.06458675
40Achilles tendon contracture (HP:0001771)2.05362272
41Protrusio acetabuli (HP:0003179)2.03146356
42Cutis marmorata (HP:0000965)2.03074005
43Deep palmar crease (HP:0006191)2.02474033
44Asymmetry of the thorax (HP:0001555)2.01722684
45Trigonocephaly (HP:0000243)2.01438658
46Ankyloglossia (HP:0010296)2.00771220
47Enlarged penis (HP:0000040)1.99515134
48Hematochezia (HP:0002573)1.99219553
49Increased connective tissue (HP:0009025)1.99106692
50Pseudobulbar signs (HP:0002200)1.98538841
51Prominent nose (HP:0000448)1.95375387
52Disproportionate tall stature (HP:0001519)1.94722244
53Bladder diverticulum (HP:0000015)1.93628967
54Absent frontal sinuses (HP:0002688)1.92588218
55Vertebral compression fractures (HP:0002953)1.92344922
56Bicuspid aortic valve (HP:0001647)1.91706282
57Broad palm (HP:0001169)1.90844829
58Bowel diverticulosis (HP:0005222)1.90666125
59Malignant gastrointestinal tract tumors (HP:0006749)1.90536233
60Gastrointestinal carcinoma (HP:0002672)1.90536233
61Selective tooth agenesis (HP:0001592)1.90382507
62Arnold-Chiari malformation (HP:0002308)1.90109811
63Pointed chin (HP:0000307)1.90036760
64Mitral regurgitation (HP:0001653)1.89908388
65Cutaneous melanoma (HP:0012056)1.89895263
66Abnormality of the calcaneus (HP:0008364)1.89048828
67Recurrent viral infections (HP:0004429)1.88562635
68Abnormality of oral frenula (HP:0000190)1.88375271
69Truncal obesity (HP:0001956)1.88215709
70Abnormality of the thoracic spine (HP:0100711)1.87957405
71Ependymoma (HP:0002888)1.87877920
72Ankle contracture (HP:0006466)1.83551581
73Abnormality of the astrocytes (HP:0100707)1.82906009
74Astrocytoma (HP:0009592)1.82906009
75Metaphyseal cupping (HP:0003021)1.82124463
76Gastrointestinal inflammation (HP:0004386)1.81845746
77Germ cell neoplasia (HP:0100728)1.81271308
78Supernumerary ribs (HP:0005815)1.80690355
79Skin tags (HP:0010609)1.80546272
80Abnormality of the nasal mucosa (HP:0000433)1.80451965
81Vertebral arch anomaly (HP:0008438)1.80355310
82Hallux valgus (HP:0001822)1.80188807
83Thin bony cortex (HP:0002753)1.79124749
84Lower limb amyotrophy (HP:0007210)1.78428948
85Trismus (HP:0000211)1.76929031
86Genu recurvatum (HP:0002816)1.76707373
87Insomnia (HP:0100785)1.76703188
88Obsessive-compulsive behavior (HP:0000722)1.76702127
89Abnormality of the Achilles tendon (HP:0005109)1.76464391
90Aneurysm (HP:0002617)1.76245198
91Biconcave vertebral bodies (HP:0004586)1.75990156
92Overriding aorta (HP:0002623)1.75776459
93Deviation of the hallux (HP:0010051)1.75710999
94Broad distal phalanx of finger (HP:0009836)1.75685515
95Basal cell carcinoma (HP:0002671)1.75474113
96Recurrent bronchitis (HP:0002837)1.75432303
97Sandal gap (HP:0001852)1.75161996
98Narrow palate (HP:0000189)1.75129838
99Syringomyelia (HP:0003396)1.74441041
100Spinal cord lesions (HP:0100561)1.74441041
101Turricephaly (HP:0000262)1.74067824
102Sparse lateral eyebrow (HP:0005338)1.73519763
103High anterior hairline (HP:0009890)1.73100693
104Dilatation of the ascending aorta (HP:0005111)1.72958188
105Deep philtrum (HP:0002002)1.72396720
106Thin ribs (HP:0000883)1.72372940
107Advanced eruption of teeth (HP:0006288)1.70716617
108Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.70531610
109Urethral obstruction (HP:0000796)1.69917123
110Fragile skin (HP:0001030)1.69052614
111Segmental peripheral demyelination/remyelination (HP:0003481)1.68487169
112Colitis (HP:0002583)1.68259049
113Abnormality of the peritoneum (HP:0002585)1.67711246
114Increased variability in muscle fiber diameter (HP:0003557)1.67202063
115Dislocated radial head (HP:0003083)1.66946163
116Persistence of primary teeth (HP:0006335)1.66887832
117Limited elbow extension (HP:0001377)1.66595890
118Transitional cell carcinoma of the bladder (HP:0006740)1.66448811
119Inflammation of the large intestine (HP:0002037)1.66031468
120Broad thumb (HP:0011304)1.65600447
121Abnormality of the intervertebral disk (HP:0005108)1.65569476
122Agammaglobulinemia (HP:0004432)1.64663740
123Septate vagina (HP:0001153)1.63789283
124Ectopic kidney (HP:0000086)1.63422986
125Flat cornea (HP:0007720)1.63302540
126Hyperparathyroidism (HP:0000843)1.63133820
127Lymphangioma (HP:0100764)1.63081439
128Osteolytic defects of the phalanges of the hand (HP:0009771)1.62337397
129Osteolytic defects of the hand bones (HP:0009699)1.62337397
130Abnormality of the distal phalanges of the toes (HP:0010182)1.62319073
131Thick eyebrow (HP:0000574)1.61956533
132Abnormality of the columella (HP:0009929)1.61589429
133Abnormality of skeletal muscle fiber size (HP:0012084)1.61084546
134Back pain (HP:0003418)1.60181474
135Leiomyosarcoma (HP:0100243)1.59721295
136Uterine leiomyosarcoma (HP:0002891)1.59721295
137Flared metaphyses (HP:0003015)1.59093211
138Abnormal platelet volume (HP:0011876)1.58812417
139Precocious puberty (HP:0000826)1.58646704
140Spinal rigidity (HP:0003306)1.58056092
141Hand muscle atrophy (HP:0009130)1.57190869
142Spina bifida occulta (HP:0003298)1.56943721
143Smooth philtrum (HP:0000319)1.56824816
144Low anterior hairline (HP:0000294)1.56385392
145Abnormality of the radial head (HP:0003995)1.56380202
146Cervical subluxation (HP:0003308)1.56240931
147Skull defect (HP:0001362)1.56039470
148Wormian bones (HP:0002645)1.55723460
149Spontaneous hematomas (HP:0007420)1.54838462
150Bladder carcinoma (HP:0002862)1.54493570
151Premature skin wrinkling (HP:0100678)1.53959206
152Abnormality of the humeroradial joint (HP:0100744)1.53895041
153Bowel incontinence (HP:0002607)1.53686189
154Upper limb amyotrophy (HP:0009129)1.52640092
155Distal upper limb amyotrophy (HP:0007149)1.52640092
156Hypercortisolism (HP:0001578)1.51832129
157Termporal pattern (HP:0011008)1.51303427
158Insidious onset (HP:0003587)1.51303427
159Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.48657774
160Thoracic kyphosis (HP:0002942)1.48465320

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.57343629
2EEF2K4.42864909
3MAP3K104.19526786
4SMG13.87847129
5TRIB33.66359218
6PRPF4B3.34316912
7PKN23.23407768
8NEK22.16850116
9CDC72.16308651
10MAP4K12.05675155
11STK102.02869718
12ICK2.01152637
13IRAK31.95792685
14ERN11.84587115
15PTK61.78450960
16BRD41.74085209
17SIK11.69129088
18CAMK1D1.60035606
19CAMK1G1.57602098
20CDK61.53105749
21TTN1.48647961
22CDK41.46592527
23GRK61.40330952
24MTOR1.37608559
25LRRK21.36661900
26STK41.33250283
27RPS6KB21.31274262
28RIPK11.30069450
29BMX1.24699637
30SIK21.21851759
31MAP3K131.19668145
32PDGFRA1.17256731
33ALK1.16627669
34FGFR31.15582215
35STK31.11309284
36NME21.08065487
37EPHA21.07820039
38PIM11.07492256
39DMPK1.05302516
40CDK91.03424797
41RPS6KA41.00519883
42KSR20.99444540
43SCYL20.99304529
44LATS10.97987653
45SIK30.96349306
46MARK20.96102719
47MAP2K30.95027483
48PAK40.94341438
49LATS20.93607636
50EPHB10.92279072
51MAP3K80.91971827
52DYRK1B0.88857483
53TESK10.86603937
54PASK0.86145143
55CSF1R0.84589132
56ATR0.84416856
57CDC42BPA0.82629612
58CHEK10.81389693
59CDK70.80852127
60PAK20.80729020
61BTK0.79610304
62CHUK0.78454969
63FGFR40.78080603
64MAP2K20.76770142
65JAK30.76424469
66TAOK20.74725225
67TESK20.72584574
68HIPK20.72527818
69MST1R0.72250780
70CLK10.70906812
71ZAP700.69416106
72TGFBR20.68921412
73FGFR20.68381882
74PDGFRB0.68290234
75IRAK20.67445876
76FLT30.67369512
77TTK0.67300576
78CSK0.66534698
79HCK0.64099411
80ATM0.64001178
81TYK20.63884040
82TRPM70.63801167
83RPS6KA20.63385869
84IRAK40.62916815
85PRKD30.61947767
86CDK80.61781570
87* CDK20.61217240
88PDPK10.61005939
89BRAF0.60486401
90ITK0.59834873
91MAP3K140.59753744
92TYRO30.59200309
93AURKB0.58966023
94SGK30.57722255
95JAK10.57308664
96MAP3K10.56839674
97NTRK10.55128380
98MAP3K70.54901029
99MELK0.53386796
100RIPK40.52478064
101PRKD20.50627863
102TGFBR10.50289180
103PRKCH0.48243843
104ARAF0.47672366
105RPS6KA10.47068032
106MAPK110.45448920
107FGFR10.45244020
108MAP3K90.45114039
109MARK30.44512989
110MAPK140.43702091
111WNK10.42921229
112ILK0.42307112
113TAOK10.41836524
114MOS0.40996918
115RET0.40970183
116JAK20.40874519
117CSNK1D0.40775239
118MAPK10.40438867
119RPS6KL10.40055510
120RPS6KC10.40055510
121CAMKK10.40030480
122CHEK20.39918467
123* CDK10.38515757
124AKT10.37994079
125AKT20.36731167
126MAP3K30.36522616
127BRSK10.36013504
128MAPKAPK20.35938759
129BLK0.35374280
130RPS6KA60.35250065
131LCK0.34285408
132PTK20.33451837
133MAPK100.32801107

Predicted pathways (KEGG)

RankGene SetZ-score
1Chronic myeloid leukemia_Homo sapiens_hsa052202.18907502
2Lysine degradation_Homo sapiens_hsa003101.96155948
3B cell receptor signaling pathway_Homo sapiens_hsa046621.83285518
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.75553330
5Small cell lung cancer_Homo sapiens_hsa052221.72645944
6MicroRNAs in cancer_Homo sapiens_hsa052061.66659293
7Primary immunodeficiency_Homo sapiens_hsa053401.64648179
8Acute myeloid leukemia_Homo sapiens_hsa052211.61046988
9Notch signaling pathway_Homo sapiens_hsa043301.60760668
10mRNA surveillance pathway_Homo sapiens_hsa030151.59863133
11Cell cycle_Homo sapiens_hsa041101.59547563
12Viral carcinogenesis_Homo sapiens_hsa052031.57542380
13Adherens junction_Homo sapiens_hsa045201.56069168
14Systemic lupus erythematosus_Homo sapiens_hsa053221.55630193
15Non-small cell lung cancer_Homo sapiens_hsa052231.50436057
16Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.42831282
17Transcriptional misregulation in cancer_Homo sapiens_hsa052021.42412588
18Pancreatic cancer_Homo sapiens_hsa052121.40834501
19Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.40161122
20mTOR signaling pathway_Homo sapiens_hsa041501.40092247
21HTLV-I infection_Homo sapiens_hsa051661.36751908
22Antigen processing and presentation_Homo sapiens_hsa046121.36721418
23Viral myocarditis_Homo sapiens_hsa054161.34951845
24DNA replication_Homo sapiens_hsa030301.34050755
25Colorectal cancer_Homo sapiens_hsa052101.32616023
26Endometrial cancer_Homo sapiens_hsa052131.32106141
27ErbB signaling pathway_Homo sapiens_hsa040121.31224623
28Proteoglycans in cancer_Homo sapiens_hsa052051.30943319
29Osteoclast differentiation_Homo sapiens_hsa043801.27411075
30Pentose phosphate pathway_Homo sapiens_hsa000301.24483601
31Toxoplasmosis_Homo sapiens_hsa051451.24328991
32Dorso-ventral axis formation_Homo sapiens_hsa043201.23057650
33Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.22707574
34Spliceosome_Homo sapiens_hsa030401.22533124
35Prostate cancer_Homo sapiens_hsa052151.21215493
36AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.21003357
37Leukocyte transendothelial migration_Homo sapiens_hsa046701.20348686
38Thyroid hormone signaling pathway_Homo sapiens_hsa049191.19490543
39Focal adhesion_Homo sapiens_hsa045101.18028240
40Hepatitis B_Homo sapiens_hsa051611.17783447
41RNA transport_Homo sapiens_hsa030131.14127088
42T cell receptor signaling pathway_Homo sapiens_hsa046601.14031197
43Glioma_Homo sapiens_hsa052141.12532426
44Herpes simplex infection_Homo sapiens_hsa051681.12517519
45Measles_Homo sapiens_hsa051621.12492167
46Central carbon metabolism in cancer_Homo sapiens_hsa052301.11476760
47NF-kappa B signaling pathway_Homo sapiens_hsa040641.10779450
48One carbon pool by folate_Homo sapiens_hsa006701.10240906
49Leishmaniasis_Homo sapiens_hsa051401.08562135
50Prion diseases_Homo sapiens_hsa050201.04621787
51Neurotrophin signaling pathway_Homo sapiens_hsa047221.03965787
52Basal cell carcinoma_Homo sapiens_hsa052171.03258268
53Base excision repair_Homo sapiens_hsa034101.03053790
54Choline metabolism in cancer_Homo sapiens_hsa052311.02660789
55p53 signaling pathway_Homo sapiens_hsa041151.02493593
56Insulin resistance_Homo sapiens_hsa049311.01707694
57Other glycan degradation_Homo sapiens_hsa005111.01040426
58Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.00884991
59Apoptosis_Homo sapiens_hsa042101.00812030
60Renal cell carcinoma_Homo sapiens_hsa052110.96696410
61FoxO signaling pathway_Homo sapiens_hsa040680.93203154
62Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.93147856
63Platelet activation_Homo sapiens_hsa046110.93125817
64Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.92523081
65VEGF signaling pathway_Homo sapiens_hsa043700.91352825
66Bladder cancer_Homo sapiens_hsa052190.89666123
67Phospholipase D signaling pathway_Homo sapiens_hsa040720.89133796
68Inositol phosphate metabolism_Homo sapiens_hsa005620.88569696
69Pathways in cancer_Homo sapiens_hsa052000.88138946
70Jak-STAT signaling pathway_Homo sapiens_hsa046300.86621531
71Phosphatidylinositol signaling system_Homo sapiens_hsa040700.86585737
72Prolactin signaling pathway_Homo sapiens_hsa049170.85809790
73Hepatitis C_Homo sapiens_hsa051600.85700480
74Mismatch repair_Homo sapiens_hsa034300.85299138
75Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.84903176
76Regulation of actin cytoskeleton_Homo sapiens_hsa048100.84436978
77Hippo signaling pathway_Homo sapiens_hsa043900.82770656
78Non-homologous end-joining_Homo sapiens_hsa034500.82446705
79Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.81388360
80Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.81234636
81HIF-1 signaling pathway_Homo sapiens_hsa040660.80844664
82Biosynthesis of amino acids_Homo sapiens_hsa012300.80013193
83Longevity regulating pathway - mammal_Homo sapiens_hsa042110.79361688
84ECM-receptor interaction_Homo sapiens_hsa045120.79036129
85Thyroid cancer_Homo sapiens_hsa052160.78929465
86AMPK signaling pathway_Homo sapiens_hsa041520.78638420
87GnRH signaling pathway_Homo sapiens_hsa049120.77892848
88Melanoma_Homo sapiens_hsa052180.77835989
89Amoebiasis_Homo sapiens_hsa051460.76279229
90Fructose and mannose metabolism_Homo sapiens_hsa000510.74512833
91TGF-beta signaling pathway_Homo sapiens_hsa043500.73753265
92Shigellosis_Homo sapiens_hsa051310.73529751
93Intestinal immune network for IgA production_Homo sapiens_hsa046720.73171542
94Epstein-Barr virus infection_Homo sapiens_hsa051690.73166212
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.70892824
96Carbohydrate digestion and absorption_Homo sapiens_hsa049730.70873069
97Chemokine signaling pathway_Homo sapiens_hsa040620.70612527
98Insulin signaling pathway_Homo sapiens_hsa049100.69433177
99Alcoholism_Homo sapiens_hsa050340.69039069
100Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.68680716
101Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.68179030
102Sphingolipid signaling pathway_Homo sapiens_hsa040710.67928804
103Estrogen signaling pathway_Homo sapiens_hsa049150.66820373
104* Influenza A_Homo sapiens_hsa051640.65999945
105Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.65684154
106Hematopoietic cell lineage_Homo sapiens_hsa046400.65315449
107TNF signaling pathway_Homo sapiens_hsa046680.64826185
108Fanconi anemia pathway_Homo sapiens_hsa034600.64724342
109Long-term potentiation_Homo sapiens_hsa047200.64347996
110Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.63307421
111Melanogenesis_Homo sapiens_hsa049160.62974197
112Selenocompound metabolism_Homo sapiens_hsa004500.62634382
113Cyanoamino acid metabolism_Homo sapiens_hsa004600.62603048
114Type II diabetes mellitus_Homo sapiens_hsa049300.61874177
115Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.61809839
116Wnt signaling pathway_Homo sapiens_hsa043100.61254166
117Toll-like receptor signaling pathway_Homo sapiens_hsa046200.60565547
118Hedgehog signaling pathway_Homo sapiens_hsa043400.56101857
119Glucagon signaling pathway_Homo sapiens_hsa049220.55957687
120Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.55775589
121Adipocytokine signaling pathway_Homo sapiens_hsa049200.55537099
122Endocytosis_Homo sapiens_hsa041440.52971057
123Galactose metabolism_Homo sapiens_hsa000520.52226067
124Rap1 signaling pathway_Homo sapiens_hsa040150.51784953
125Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.50159920
126MAPK signaling pathway_Homo sapiens_hsa040100.48986567

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