

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of gene silencing (GO:0060969) | 9.57568531 |
| 2 | fatty acid elongation (GO:0030497) | 8.56082903 |
| 3 | behavioral response to nicotine (GO:0035095) | 6.03818796 |
| 4 | skeletal muscle tissue regeneration (GO:0043403) | 5.84344814 |
| 5 | intra-S DNA damage checkpoint (GO:0031573) | 5.67488853 |
| 6 | membrane tubulation (GO:0097320) | 5.59308033 |
| 7 | DNA damage response, detection of DNA damage (GO:0042769) | 5.44630296 |
| 8 | response to pheromone (GO:0019236) | 5.42181574 |
| 9 | positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968) | 5.35475196 |
| 10 | nucleoside diphosphate catabolic process (GO:0009134) | 5.33845273 |
| 11 | myoblast migration (GO:0051451) | 5.27959819 |
| 12 | viral transcription (GO:0019083) | 5.17800511 |
| 13 | ribosomal small subunit biogenesis (GO:0042274) | 5.11598642 |
| 14 | translational termination (GO:0006415) | 5.02504246 |
| 15 | positive regulation of cell cycle G2/M phase transition (GO:1902751) | 4.90371723 |
| 16 | positive regulation of G2/M transition of mitotic cell cycle (GO:0010971) | 4.90371723 |
| 17 | sequestering of actin monomers (GO:0042989) | 4.86243532 |
| 18 | heart trabecula morphogenesis (GO:0061384) | 4.82050561 |
| 19 | regulation of DNA damage checkpoint (GO:2000001) | 4.77930283 |
| 20 | maturation of SSU-rRNA (GO:0030490) | 4.51570261 |
| 21 | negative regulation of striated muscle cell apoptotic process (GO:0010664) | 4.48007332 |
| 22 | inner cell mass cell proliferation (GO:0001833) | 4.46839115 |
| 23 | regulation of transcription from RNA polymerase II promoter involved in heart development (GO:190121 | 4.37475546 |
| 24 | regulation of gene silencing (GO:0060968) | 4.30484820 |
| 25 | translational elongation (GO:0006414) | 4.21655709 |
| 26 | cellular protein complex disassembly (GO:0043624) | 3.95578529 |
| 27 | macrophage chemotaxis (GO:0048246) | 3.91215946 |
| 28 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.90365266 |
| 29 | cotranslational protein targeting to membrane (GO:0006613) | 3.88733914 |
| 30 | long-chain fatty-acyl-CoA biosynthetic process (GO:0035338) | 3.88649412 |
| 31 | positive regulation of skeletal muscle tissue development (GO:0048643) | 3.84609381 |
| 32 | protein targeting to ER (GO:0045047) | 3.82945628 |
| 33 | viral life cycle (GO:0019058) | 3.78501627 |
| 34 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.69000278 |
| 35 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.67620478 |
| 36 | autophagic vacuole fusion (GO:0000046) | 3.62684253 |
| 37 | RNA methylation (GO:0001510) | 3.60635929 |
| 38 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.57725493 |
| 39 | ribosomal small subunit assembly (GO:0000028) | 3.57240074 |
| 40 | response to nitrosative stress (GO:0051409) | 3.53770627 |
| 41 | protein localization to endoplasmic reticulum (GO:0070972) | 3.50250508 |
| 42 | microglial cell activation (GO:0001774) | 3.43156737 |
| 43 | protein complex disassembly (GO:0043241) | 3.41993994 |
| 44 | trabecula morphogenesis (GO:0061383) | 3.38772123 |
| 45 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.36423326 |
| 46 | renal system development (GO:0072001) | 3.33943626 |
| 47 | fatty-acyl-CoA biosynthetic process (GO:0046949) | 3.32968132 |
| 48 | regulation of cell proliferation involved in heart morphogenesis (GO:2000136) | 3.32546543 |
| 49 | phagocytosis, engulfment (GO:0006911) | 3.31303289 |
| 50 | positive regulation of DNA-templated transcription, elongation (GO:0032786) | 3.30233012 |
| 51 | macromolecular complex disassembly (GO:0032984) | 3.29263610 |
| 52 | regulation of G2/M transition of mitotic cell cycle (GO:0010389) | 3.24605692 |
| 53 | cell proliferation in forebrain (GO:0021846) | 3.23648787 |
| 54 | regulation of transcription elongation from RNA polymerase II promoter (GO:0034243) | 3.21527051 |
| 55 | somite development (GO:0061053) | 3.21464841 |
| 56 | long-chain fatty-acyl-CoA metabolic process (GO:0035336) | 3.21397992 |
| 57 | negative regulation of G2/M transition of mitotic cell cycle (GO:0010972) | 3.19736543 |
| 58 | positive regulation of gastrulation (GO:2000543) | 3.19269204 |
| 59 | regulation of cell cycle checkpoint (GO:1901976) | 3.18688685 |
| 60 | regulation of cell cycle G2/M phase transition (GO:1902749) | 3.14170602 |
| 61 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 3.11060600 |
| 62 | regulation of striated muscle cell apoptotic process (GO:0010662) | 3.08609689 |
| 63 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 3.04889102 |
| 64 | negative regulation of cell cycle G2/M phase transition (GO:1902750) | 3.03179760 |
| 65 | mitotic chromosome condensation (GO:0007076) | 2.99047377 |
| 66 | protein polyglutamylation (GO:0018095) | 2.98610093 |
| 67 | chromosome condensation (GO:0030261) | 2.96531395 |
| 68 | response to xenobiotic stimulus (GO:0009410) | 2.94260393 |
| 69 | mannosylation (GO:0097502) | 2.92167784 |
| 70 | negative regulation of meiosis (GO:0045835) | 2.91521738 |
| 71 | cell junction maintenance (GO:0034331) | 2.86477372 |
| 72 | positive regulation of DNA binding (GO:0043388) | 2.84822828 |
| 73 | chemokine-mediated signaling pathway (GO:0070098) | 2.84167196 |
| 74 | cellular response to gamma radiation (GO:0071480) | 2.83236723 |
| 75 | acyl-CoA biosynthetic process (GO:0071616) | 2.78889068 |
| 76 | thioester biosynthetic process (GO:0035384) | 2.78889068 |
| 77 | defense response to Gram-negative bacterium (GO:0050829) | 2.78583106 |
| 78 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.78421390 |
| 79 | chromatin remodeling at centromere (GO:0031055) | 2.77063757 |
| 80 | translational initiation (GO:0006413) | 2.75701130 |
| 81 | neuron fate specification (GO:0048665) | 2.74870156 |
| 82 | histone mRNA metabolic process (GO:0008334) | 2.72757858 |
| 83 | neuron fate determination (GO:0048664) | 2.72538257 |
| 84 | chaperone-mediated protein transport (GO:0072321) | 2.72501368 |
| 85 | peptidyl-arginine methylation (GO:0018216) | 2.72343287 |
| 86 | peptidyl-arginine N-methylation (GO:0035246) | 2.72343287 |
| 87 | cellular defense response (GO:0006968) | 2.71163402 |
| 88 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.70341219 |
| 89 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.70334440 |
| 90 | regulation of odontogenesis of dentin-containing tooth (GO:0042487) | 2.67936676 |
| 91 | regulation of heart morphogenesis (GO:2000826) | 2.65944855 |
| 92 | dopaminergic neuron differentiation (GO:0071542) | 2.63408175 |
| 93 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.60493921 |
| 94 | fatty-acyl-CoA metabolic process (GO:0035337) | 2.57994020 |
| 95 | macrophage activation involved in immune response (GO:0002281) | 2.57741343 |
| 96 | mRNA catabolic process (GO:0006402) | 2.54625284 |
| 97 | regulation of posttranscriptional gene silencing (GO:0060147) | 11.6376217 |
| 98 | regulation of gene silencing by miRNA (GO:0060964) | 11.6376217 |
| 99 | regulation of gene silencing by RNA (GO:0060966) | 11.6376217 |
| 100 | histone H4-K12 acetylation (GO:0043983) | 11.0213863 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.01441649 |
| 2 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.82719273 |
| 3 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.42163464 |
| 4 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 3.03531151 |
| 5 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.77892023 |
| 6 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.76099249 |
| 7 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.55939968 |
| 8 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.54016000 |
| 9 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.50320437 |
| 10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.41099110 |
| 11 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.32870640 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.31432721 |
| 13 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.26777484 |
| 14 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 2.23099606 |
| 15 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 2.22531237 |
| 16 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.20470068 |
| 17 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.19427754 |
| 18 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.18827814 |
| 19 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.14344655 |
| 20 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.08809935 |
| 21 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 2.08629354 |
| 22 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 2.04623353 |
| 23 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.98198636 |
| 24 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.96931197 |
| 25 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.88792038 |
| 26 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.78623360 |
| 27 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.72506166 |
| 28 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.68490484 |
| 29 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.68395460 |
| 30 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.62556037 |
| 31 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.59863195 |
| 32 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.58772232 |
| 33 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.57864471 |
| 34 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.56146949 |
| 35 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 1.55226454 |
| 36 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.51097535 |
| 37 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.47331303 |
| 38 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.46207731 |
| 39 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.46012130 |
| 40 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.44943032 |
| 41 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.44890981 |
| 42 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.44155603 |
| 43 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.44095792 |
| 44 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.44095792 |
| 45 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.44013537 |
| 46 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.43905767 |
| 47 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.43360405 |
| 48 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.40379329 |
| 49 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.39018274 |
| 50 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.38781689 |
| 51 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.38118537 |
| 52 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.32658967 |
| 53 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.32600663 |
| 54 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.31647387 |
| 55 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.28240890 |
| 56 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.28240890 |
| 57 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.28078944 |
| 58 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.25511153 |
| 59 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.23624554 |
| 60 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.23347850 |
| 61 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.22789976 |
| 62 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.22238980 |
| 63 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.21389848 |
| 64 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.20461759 |
| 65 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.19569789 |
| 66 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.19077245 |
| 67 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.18732825 |
| 68 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.18140015 |
| 69 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 1.12641090 |
| 70 | FUS_26573619_Chip-Seq_HEK293_Human | 1.12152746 |
| 71 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.10723739 |
| 72 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.10159585 |
| 73 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.09796917 |
| 74 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.09506501 |
| 75 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.07034972 |
| 76 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.04928274 |
| 77 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.03094810 |
| 78 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.02475292 |
| 79 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.02033213 |
| 80 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.01995634 |
| 81 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.01804769 |
| 82 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.00456484 |
| 83 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.99097698 |
| 84 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.98943826 |
| 85 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.98293572 |
| 86 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.98113762 |
| 87 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.98009587 |
| 88 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.97879249 |
| 89 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.96810150 |
| 90 | ERA_21632823_ChIP-Seq_H3396_Human | 0.95697090 |
| 91 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.94871632 |
| 92 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.93860486 |
| 93 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.92886388 |
| 94 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.92879733 |
| 95 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.92149787 |
| 96 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.91178705 |
| 97 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.90483268 |
| 98 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 0.89929441 |
| 99 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.88692419 |
| 100 | FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.88546474 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.75688166 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.38774592 |
| 3 | MP0001188_hyperpigmentation | 3.68712143 |
| 4 | MP0003567_abnormal_fetal_cardiomyocyte | 3.15152581 |
| 5 | MP0003011_delayed_dark_adaptation | 2.78024516 |
| 6 | MP0004185_abnormal_adipocyte_glucose | 2.72110968 |
| 7 | MP0006082_CNS_inflammation | 2.58416475 |
| 8 | MP0008789_abnormal_olfactory_epithelium | 2.41781053 |
| 9 | MP0004142_abnormal_muscle_tone | 2.36401676 |
| 10 | MP0000750_abnormal_muscle_regeneration | 2.30924814 |
| 11 | MP0001293_anophthalmia | 2.24791614 |
| 12 | MP0000685_abnormal_immune_system | 2.10378373 |
| 13 | MP0008260_abnormal_autophagy | 2.04069267 |
| 14 | MP0003283_abnormal_digestive_organ | 2.01167947 |
| 15 | MP0000049_abnormal_middle_ear | 1.99859304 |
| 16 | MP0000566_synostosis | 1.98807444 |
| 17 | MP0001915_intracranial_hemorrhage | 1.92479351 |
| 18 | MP0005671_abnormal_response_to | 1.91289719 |
| 19 | MP0000631_abnormal_neuroendocrine_gland | 1.81825686 |
| 20 | MP0004885_abnormal_endolymph | 1.78915363 |
| 21 | MP0003646_muscle_fatigue | 1.78727668 |
| 22 | MP0004883_abnormal_blood_vessel | 1.73356141 |
| 23 | MP0000383_abnormal_hair_follicle | 1.71431858 |
| 24 | MP0005499_abnormal_olfactory_system | 1.70774536 |
| 25 | MP0005394_taste/olfaction_phenotype | 1.70774536 |
| 26 | MP0004019_abnormal_vitamin_homeostasis | 1.68576081 |
| 27 | MP0001485_abnormal_pinna_reflex | 1.59727648 |
| 28 | MP0003787_abnormal_imprinting | 1.56555318 |
| 29 | MP0000026_abnormal_inner_ear | 1.55573798 |
| 30 | MP0000372_irregular_coat_pigmentation | 1.54160945 |
| 31 | MP0005171_absent_coat_pigmentation | 1.53392662 |
| 32 | MP0005551_abnormal_eye_electrophysiolog | 1.48307076 |
| 33 | MP0002234_abnormal_pharynx_morphology | 1.47990287 |
| 34 | MP0003936_abnormal_reproductive_system | 1.42749444 |
| 35 | MP0002928_abnormal_bile_duct | 1.41638672 |
| 36 | MP0002697_abnormal_eye_size | 1.37430019 |
| 37 | MP0000534_abnormal_ureter_morphology | 1.36748746 |
| 38 | MP0001905_abnormal_dopamine_level | 1.36279444 |
| 39 | MP0005195_abnormal_posterior_eye | 1.34159721 |
| 40 | MP0002138_abnormal_hepatobiliary_system | 1.32554556 |
| 41 | MP0002736_abnormal_nociception_after | 1.32263518 |
| 42 | MP0002638_abnormal_pupillary_reflex | 1.31798618 |
| 43 | MP0009053_abnormal_anal_canal | 1.30293714 |
| 44 | MP0002938_white_spotting | 1.30183252 |
| 45 | MP0010030_abnormal_orbit_morphology | 1.28392535 |
| 46 | MP0002184_abnormal_innervation | 1.27496627 |
| 47 | MP0003880_abnormal_central_pattern | 1.17930683 |
| 48 | MP0000778_abnormal_nervous_system | 1.16797539 |
| 49 | MP0002653_abnormal_ependyma_morphology | 1.16751364 |
| 50 | MP0003938_abnormal_ear_development | 1.15638087 |
| 51 | MP0004742_abnormal_vestibular_system | 1.15500401 |
| 52 | MP0009333_abnormal_splenocyte_physiolog | 1.14906232 |
| 53 | MP0005423_abnormal_somatic_nervous | 1.12480591 |
| 54 | MP0003890_abnormal_embryonic-extraembry | 1.10645304 |
| 55 | MP0003122_maternal_imprinting | 1.08676495 |
| 56 | MP0005448_abnormal_energy_balance | 1.06047669 |
| 57 | MP0003755_abnormal_palate_morphology | 1.06037161 |
| 58 | MP0003942_abnormal_urinary_system | 1.05705643 |
| 59 | MP0001286_abnormal_eye_development | 1.05561867 |
| 60 | MP0002116_abnormal_craniofacial_bone | 1.03268967 |
| 61 | MP0002210_abnormal_sex_determination | 0.99259826 |
| 62 | MP0002233_abnormal_nose_morphology | 0.95527827 |
| 63 | MP0000427_abnormal_hair_cycle | 0.93481392 |
| 64 | MP0002098_abnormal_vibrissa_morphology | 0.93350172 |
| 65 | MP0003121_genomic_imprinting | 0.93349964 |
| 66 | MP0002277_abnormal_respiratory_mucosa | 0.92882243 |
| 67 | MP0004957_abnormal_blastocyst_morpholog | 0.91938241 |
| 68 | MP0005197_abnormal_uvea_morphology | 0.91058192 |
| 69 | MP0000955_abnormal_spinal_cord | 0.90818533 |
| 70 | MP0003119_abnormal_digestive_system | 0.90042028 |
| 71 | MP0004130_abnormal_muscle_cell | 0.89313546 |
| 72 | MP0002751_abnormal_autonomic_nervous | 0.88074164 |
| 73 | MP0001929_abnormal_gametogenesis | 0.87235823 |
| 74 | MP0002163_abnormal_gland_morphology | 0.84701704 |
| 75 | MP0005391_vision/eye_phenotype | 0.83246452 |
| 76 | MP0003937_abnormal_limbs/digits/tail_de | 0.83138638 |
| 77 | MP0002102_abnormal_ear_morphology | 0.80424351 |
| 78 | MP0001324_abnormal_eye_pigmentation | 0.79815936 |
| 79 | MP0001727_abnormal_embryo_implantation | 0.78202828 |
| 80 | MP0005166_decreased_susceptibility_to | 0.78113411 |
| 81 | MP0006072_abnormal_retinal_apoptosis | 0.76828352 |
| 82 | MP0001243_abnormal_dermal_layer | 0.75623834 |
| 83 | MP0001145_abnormal_male_reproductive | 0.75448790 |
| 84 | MP0004133_heterotaxia | 0.74332000 |
| 85 | MP0002160_abnormal_reproductive_system | 0.72443345 |
| 86 | MP0002092_abnormal_eye_morphology | 0.72176296 |
| 87 | MP0002876_abnormal_thyroid_physiology | 0.71594508 |
| 88 | MP0002971_abnormal_brown_adipose | 0.71591876 |
| 89 | MP0000653_abnormal_sex_gland | 0.70259652 |
| 90 | MP0005410_abnormal_fertilization | 0.69463459 |
| 91 | MP0003315_abnormal_perineum_morphology | 0.68936564 |
| 92 | MP0001963_abnormal_hearing_physiology | 0.68658641 |
| 93 | MP0004858_abnormal_nervous_system | 0.68392283 |
| 94 | MP0002752_abnormal_somatic_nervous | 0.67715055 |
| 95 | MP0000569_abnormal_digit_pigmentation | 0.67656147 |
| 96 | MP0008877_abnormal_DNA_methylation | 0.65025276 |
| 97 | MP0003698_abnormal_male_reproductive | 0.64992168 |
| 98 | MP0004811_abnormal_neuron_physiology | 0.64907710 |
| 99 | MP0005389_reproductive_system_phenotype | 0.63763635 |
| 100 | MP0010678_abnormal_skin_adnexa | 0.63443533 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Severe visual impairment (HP:0001141) | 7.47507278 |
| 2 | Cortical dysplasia (HP:0002539) | 5.07137217 |
| 3 | Deep palmar crease (HP:0006191) | 4.60092200 |
| 4 | Congenital stationary night blindness (HP:0007642) | 4.21736543 |
| 5 | Scotoma (HP:0000575) | 4.14237121 |
| 6 | Epidermoid cyst (HP:0200040) | 3.89880661 |
| 7 | Submucous cleft hard palate (HP:0000176) | 3.87400592 |
| 8 | Hyperlipoproteinemia (HP:0010980) | 3.73551118 |
| 9 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.70373414 |
| 10 | Impulsivity (HP:0100710) | 3.54717883 |
| 11 | Type 2 muscle fiber atrophy (HP:0003554) | 3.28819402 |
| 12 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.22318890 |
| 13 | Bony spicule pigmentary retinopathy (HP:0007737) | 3.19152229 |
| 14 | Abnormal number of erythroid precursors (HP:0012131) | 3.13165854 |
| 15 | Pachygyria (HP:0001302) | 3.12696536 |
| 16 | Nephronophthisis (HP:0000090) | 3.02927223 |
| 17 | Muscle fiber atrophy (HP:0100295) | 2.94234308 |
| 18 | Flat capital femoral epiphysis (HP:0003370) | 2.92563872 |
| 19 | True hermaphroditism (HP:0010459) | 2.85771221 |
| 20 | Type II lissencephaly (HP:0007260) | 2.85501641 |
| 21 | Reticulocytopenia (HP:0001896) | 2.84866609 |
| 22 | Septo-optic dysplasia (HP:0100842) | 2.76276138 |
| 23 | Central scotoma (HP:0000603) | 2.71923160 |
| 24 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.70607558 |
| 25 | 3-Methylglutaconic aciduria (HP:0003535) | 2.67661168 |
| 26 | Bulbous nose (HP:0000414) | 2.67139432 |
| 27 | Oligomenorrhea (HP:0000876) | 2.66234127 |
| 28 | Cerebellar dysplasia (HP:0007033) | 2.58069795 |
| 29 | Abnormality of the aortic arch (HP:0012303) | 2.56765836 |
| 30 | Maternal diabetes (HP:0009800) | 2.53568842 |
| 31 | Rib fusion (HP:0000902) | 2.53356529 |
| 32 | Congenital, generalized hypertrichosis (HP:0004540) | 2.53248191 |
| 33 | Polymicrogyria (HP:0002126) | 2.45311719 |
| 34 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.43249202 |
| 35 | Asplenia (HP:0001746) | 2.35311946 |
| 36 | Pancreatic fibrosis (HP:0100732) | 2.32883100 |
| 37 | Hypoplastic pelvis (HP:0008839) | 2.31124415 |
| 38 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.30715565 |
| 39 | Abnormal number of incisors (HP:0011064) | 2.29617912 |
| 40 | Macrocytic anemia (HP:0001972) | 2.27419583 |
| 41 | Abnormality of the antihelix (HP:0009738) | 2.22135095 |
| 42 | Curly hair (HP:0002212) | 2.21662053 |
| 43 | Alveolar cell carcinoma (HP:0006519) | 2.19279227 |
| 44 | Lissencephaly (HP:0001339) | 2.17853864 |
| 45 | Abnormality of midbrain morphology (HP:0002418) | 2.16364945 |
| 46 | Molar tooth sign on MRI (HP:0002419) | 2.16364945 |
| 47 | Spinal cord lesions (HP:0100561) | 2.14602999 |
| 48 | Syringomyelia (HP:0003396) | 2.14602999 |
| 49 | Short femoral neck (HP:0100864) | 2.14078050 |
| 50 | Abnormality of the renal medulla (HP:0100957) | 2.13797559 |
| 51 | Adrenal hypoplasia (HP:0000835) | 2.13349302 |
| 52 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.12297979 |
| 53 | Xanthomatosis (HP:0000991) | 2.11798769 |
| 54 | Abnormality of the epiphysis of the femoral head (HP:0010574) | 2.10953918 |
| 55 | Flared iliac wings (HP:0002869) | 2.10399358 |
| 56 | Progressive microcephaly (HP:0000253) | 2.08919561 |
| 57 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.08108633 |
| 58 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.00579454 |
| 59 | Poor coordination (HP:0002370) | 2.00349079 |
| 60 | Oligodactyly (hands) (HP:0001180) | 1.98947899 |
| 61 | Medial flaring of the eyebrow (HP:0010747) | 1.98710890 |
| 62 | Depressed nasal ridge (HP:0000457) | 1.98413630 |
| 63 | Palpebral edema (HP:0100540) | 1.98044180 |
| 64 | Microvesicular hepatic steatosis (HP:0001414) | 1.93953604 |
| 65 | Sparse lateral eyebrow (HP:0005338) | 1.93077771 |
| 66 | Abnormality of macular pigmentation (HP:0008002) | 1.93024357 |
| 67 | Nephrogenic diabetes insipidus (HP:0009806) | 1.91308609 |
| 68 | Pendular nystagmus (HP:0012043) | 1.90838238 |
| 69 | Abnormality of femoral epiphyses (HP:0006499) | 1.90089859 |
| 70 | Abnormality involving the epiphyses of the lower limbs (HP:0006500) | 1.90089859 |
| 71 | Abnormality of hair growth rate (HP:0011363) | 1.89654176 |
| 72 | Slow-growing hair (HP:0002217) | 1.89654176 |
| 73 | Postaxial foot polydactyly (HP:0001830) | 1.88135748 |
| 74 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.85891316 |
| 75 | Self-mutilation (HP:0000742) | 1.85626835 |
| 76 | Skin nodule (HP:0200036) | 1.85526968 |
| 77 | Esophageal atresia (HP:0002032) | 1.85404803 |
| 78 | Hypoplasia of the radius (HP:0002984) | 1.82691233 |
| 79 | Abnormal sex determination (HP:0012244) | 1.82411227 |
| 80 | Sex reversal (HP:0012245) | 1.82411227 |
| 81 | Arthropathy (HP:0003040) | 1.82169721 |
| 82 | Type I transferrin isoform profile (HP:0003642) | 1.80450056 |
| 83 | Congenital primary aphakia (HP:0007707) | 1.79209163 |
| 84 | Poor head control (HP:0002421) | 1.78122208 |
| 85 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.75726146 |
| 86 | Abnormality of the femoral head (HP:0003368) | 1.75211235 |
| 87 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 1.75154176 |
| 88 | Abnormality of the renal cortex (HP:0011035) | 1.74982839 |
| 89 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.74292011 |
| 90 | Villous atrophy (HP:0011473) | 1.74292011 |
| 91 | Gait imbalance (HP:0002141) | 1.74127525 |
| 92 | Anterior segment dysgenesis (HP:0007700) | 1.73862628 |
| 93 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.73708236 |
| 94 | Constricted visual fields (HP:0001133) | 1.73556431 |
| 95 | Large for gestational age (HP:0001520) | 1.72208828 |
| 96 | Shawl scrotum (HP:0000049) | 1.72146523 |
| 97 | Severe muscular hypotonia (HP:0006829) | 1.72097309 |
| 98 | Pallor (HP:0000980) | 1.71463782 |
| 99 | Sloping forehead (HP:0000340) | 1.70544883 |
| 100 | Absent eyebrow (HP:0002223) | 1.69846222 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAF1 | 7.60913253 |
| 2 | AKT3 | 6.85785606 |
| 3 | IRAK4 | 5.91376471 |
| 4 | MARK3 | 3.18638015 |
| 5 | BRAF | 2.72815960 |
| 6 | KSR1 | 2.49633646 |
| 7 | ILK | 2.48144210 |
| 8 | PIK3CG | 2.39813446 |
| 9 | CDC7 | 1.91786778 |
| 10 | TESK2 | 1.85172166 |
| 11 | ZAK | 1.75204214 |
| 12 | VRK2 | 1.75059669 |
| 13 | PTK2 | 1.57707272 |
| 14 | RIPK1 | 1.46436696 |
| 15 | NEK1 | 1.38341592 |
| 16 | SGK2 | 1.32482962 |
| 17 | TLK1 | 1.30421101 |
| 18 | MAP3K11 | 1.27096458 |
| 19 | PASK | 1.26311018 |
| 20 | DYRK3 | 1.21813210 |
| 21 | LRRK2 | 1.21190045 |
| 22 | GRK1 | 1.19227587 |
| 23 | DYRK2 | 1.10630564 |
| 24 | PRKCI | 1.10382315 |
| 25 | SGK494 | 1.05486046 |
| 26 | SGK223 | 1.05486046 |
| 27 | MKNK2 | 0.99271528 |
| 28 | PINK1 | 0.98533333 |
| 29 | VRK1 | 0.98210625 |
| 30 | BUB1 | 0.97119363 |
| 31 | PIK3CA | 0.93932278 |
| 32 | UHMK1 | 0.89741728 |
| 33 | NEK2 | 0.87309094 |
| 34 | BMPR1B | 0.86415543 |
| 35 | PIM1 | 0.82059157 |
| 36 | PLK2 | 0.80582824 |
| 37 | BRSK2 | 0.80078656 |
| 38 | STK11 | 0.79535133 |
| 39 | PLK4 | 0.77037935 |
| 40 | MKNK1 | 0.76604394 |
| 41 | MAPKAPK3 | 0.75310067 |
| 42 | MAP3K9 | 0.70248855 |
| 43 | CAMK2B | 0.69389248 |
| 44 | AURKB | 0.67398588 |
| 45 | CAMK4 | 0.66764145 |
| 46 | ERN1 | 0.64527315 |
| 47 | SGK3 | 0.64470007 |
| 48 | TGFBR1 | 0.64196574 |
| 49 | MAP2K3 | 0.61460329 |
| 50 | MAPK13 | 0.60657421 |
| 51 | CHEK1 | 0.58651869 |
| 52 | PRKCZ | 0.56154234 |
| 53 | CAMK1D | 0.55525736 |
| 54 | CHUK | 0.54742232 |
| 55 | INSRR | 0.52965477 |
| 56 | ADRBK2 | 0.52242206 |
| 57 | MAP2K4 | 0.51975667 |
| 58 | TIE1 | 0.51657918 |
| 59 | CDK9 | 0.50979664 |
| 60 | PLK1 | 0.49447525 |
| 61 | EPHB1 | 0.49055068 |
| 62 | HIPK2 | 0.47670995 |
| 63 | EPHB2 | 0.47437897 |
| 64 | CSNK2A2 | 0.43394996 |
| 65 | ABL2 | 0.43250202 |
| 66 | BTK | 0.43127818 |
| 67 | MAP2K6 | 0.42260659 |
| 68 | CSNK1E | 0.41703697 |
| 69 | KIT | 0.41094039 |
| 70 | EPHA4 | 0.41020732 |
| 71 | AURKA | 0.39455217 |
| 72 | STK16 | 0.39152446 |
| 73 | ALK | 0.38966589 |
| 74 | CDK19 | 0.38873404 |
| 75 | MAPK15 | 0.38514190 |
| 76 | CSF1R | 0.38380541 |
| 77 | ERBB4 | 0.36185473 |
| 78 | MAP4K2 | 0.34156516 |
| 79 | WNK3 | 0.33250865 |
| 80 | DAPK1 | 0.32908487 |
| 81 | NLK | 0.30829790 |
| 82 | CAMK1G | 0.29065466 |
| 83 | PRKACA | 0.29027473 |
| 84 | FRK | 0.27503756 |
| 85 | STK4 | 0.26057468 |
| 86 | CSNK2A1 | 0.24457968 |
| 87 | RPS6KA4 | 0.24101469 |
| 88 | TAOK3 | 0.23889055 |
| 89 | PNCK | 0.23797655 |
| 90 | IRAK1 | 0.23663380 |
| 91 | WEE1 | 0.23084616 |
| 92 | TSSK6 | 0.22948954 |
| 93 | CDK11A | 0.22381625 |
| 94 | WNK4 | 0.22139109 |
| 95 | CDK15 | 0.21947153 |
| 96 | CDK4 | 0.21289495 |
| 97 | CAMK2D | 0.21285731 |
| 98 | PAK1 | 0.21073874 |
| 99 | RPS6KA5 | 0.20872282 |
| 100 | CDK2 | 0.20691942 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.94551033 |
| 2 | Fatty acid elongation_Homo sapiens_hsa00062 | 5.14209420 |
| 3 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 4.31630026 |
| 4 | Steroid biosynthesis_Homo sapiens_hsa00100 | 3.25906419 |
| 5 | Butanoate metabolism_Homo sapiens_hsa00650 | 3.14863698 |
| 6 | Spliceosome_Homo sapiens_hsa03040 | 2.44895236 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.39636443 |
| 8 | Phototransduction_Homo sapiens_hsa04744 | 2.24301835 |
| 9 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.13386508 |
| 10 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 2.08624263 |
| 11 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.94362625 |
| 12 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.78028266 |
| 13 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.72966842 |
| 14 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.72198647 |
| 15 | Alcoholism_Homo sapiens_hsa05034 | 1.64876339 |
| 16 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.63792937 |
| 17 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.63733960 |
| 18 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.56753218 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.55789498 |
| 20 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.52388758 |
| 21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.47243902 |
| 22 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.45975964 |
| 23 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.45380394 |
| 24 | Thyroid cancer_Homo sapiens_hsa05216 | 1.43573554 |
| 25 | Mismatch repair_Homo sapiens_hsa03430 | 1.41037069 |
| 26 | RNA degradation_Homo sapiens_hsa03018 | 1.36366121 |
| 27 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.29676815 |
| 28 | Alzheimers disease_Homo sapiens_hsa05010 | 1.18997404 |
| 29 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.14054385 |
| 30 | Proteasome_Homo sapiens_hsa03050 | 1.08909336 |
| 31 | RNA polymerase_Homo sapiens_hsa03020 | 1.08572826 |
| 32 | Basal transcription factors_Homo sapiens_hsa03022 | 1.07568779 |
| 33 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.99909154 |
| 34 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.96807200 |
| 35 | Homologous recombination_Homo sapiens_hsa03440 | 0.89284388 |
| 36 | Olfactory transduction_Homo sapiens_hsa04740 | 0.88231039 |
| 37 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.86806119 |
| 38 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.82873102 |
| 39 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.80543661 |
| 40 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.79902274 |
| 41 | Protein export_Homo sapiens_hsa03060 | 0.78781161 |
| 42 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.75900346 |
| 43 | Sulfur relay system_Homo sapiens_hsa04122 | 0.75612586 |
| 44 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.73231560 |
| 45 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.72458990 |
| 46 | Purine metabolism_Homo sapiens_hsa00230 | 0.72446918 |
| 47 | RNA transport_Homo sapiens_hsa03013 | 0.70449321 |
| 48 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.69646480 |
| 49 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.69181516 |
| 50 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.68622753 |
| 51 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.66723855 |
| 52 | Melanoma_Homo sapiens_hsa05218 | 0.63498867 |
| 53 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.63411356 |
| 54 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.61321375 |
| 55 | Melanogenesis_Homo sapiens_hsa04916 | 0.59308099 |
| 56 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.57132999 |
| 57 | Gap junction_Homo sapiens_hsa04540 | 0.54576828 |
| 58 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.53443550 |
| 59 | DNA replication_Homo sapiens_hsa03030 | 0.52918674 |
| 60 | Retinol metabolism_Homo sapiens_hsa00830 | 0.52873484 |
| 61 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.49947915 |
| 62 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.47748701 |
| 63 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.46589932 |
| 64 | Colorectal cancer_Homo sapiens_hsa05210 | 0.46048675 |
| 65 | Glioma_Homo sapiens_hsa05214 | 0.44413912 |
| 66 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.41714897 |
| 67 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.41202973 |
| 68 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.40639306 |
| 69 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.39613208 |
| 70 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.39488208 |
| 71 | Axon guidance_Homo sapiens_hsa04360 | 0.39475225 |
| 72 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.38392645 |
| 73 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.37539895 |
| 74 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.34915252 |
| 75 | Leishmaniasis_Homo sapiens_hsa05140 | 0.33227242 |
| 76 | Cocaine addiction_Homo sapiens_hsa05030 | 0.33222009 |
| 77 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.32027437 |
| 78 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.30248541 |
| 79 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.28214337 |
| 80 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.27483823 |
| 81 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.27354261 |
| 82 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.25574886 |
| 83 | Endometrial cancer_Homo sapiens_hsa05213 | 0.25378014 |
| 84 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.25121522 |
| 85 | Pertussis_Homo sapiens_hsa05133 | 0.24719036 |
| 86 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.24483583 |
| 87 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.23047830 |
| 88 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.22616297 |
| 89 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.22109994 |
| 90 | Prostate cancer_Homo sapiens_hsa05215 | 0.21754427 |
| 91 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.19199436 |
| 92 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.17927647 |
| 93 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.16819415 |
| 94 | Morphine addiction_Homo sapiens_hsa05032 | 0.16300755 |
| 95 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.15285742 |
| 96 | Metabolic pathways_Homo sapiens_hsa01100 | 0.15229813 |
| 97 | Nicotine addiction_Homo sapiens_hsa05033 | 0.14716471 |
| 98 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.13130542 |
| 99 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.12812103 |
| 100 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.11909607 |

