HOXA13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060529.99483217
2regulation of branching involved in prostate gland morphogenesis (GO:0060687)8.47887144
3* branching involved in prostate gland morphogenesis (GO:0060442)7.35374948
4embryonic skeletal joint morphogenesis (GO:0060272)5.86768095
5chondrocyte proliferation (GO:0035988)5.32518408
6proximal/distal pattern formation (GO:0009954)4.93651286
7positive regulation of cartilage development (GO:0061036)4.80453867
8morphogenesis of an epithelial fold (GO:0060571)4.68094511
9axis elongation (GO:0003401)4.63590310
10branch elongation of an epithelium (GO:0060602)4.61061249
11* forelimb morphogenesis (GO:0035136)4.53853251
12* embryonic forelimb morphogenesis (GO:0035115)4.53410982
13positive regulation of chondrocyte differentiation (GO:0032332)4.51136721
14embryonic digit morphogenesis (GO:0042733)4.47552238
15* prostate gland epithelium morphogenesis (GO:0060740)4.46182104
16midgut development (GO:0007494)4.28189491
17cartilage development involved in endochondral bone morphogenesis (GO:0060351)4.19260656
18* male genitalia development (GO:0030539)4.18672700
19lymph vessel development (GO:0001945)4.13193746
20lateral sprouting from an epithelium (GO:0060601)4.10982900
21mesenchymal cell proliferation (GO:0010463)4.10315945
22uterus development (GO:0060065)4.06510502
23planar cell polarity pathway involved in neural tube closure (GO:0090179)3.95082382
24organ induction (GO:0001759)3.91892986
25bone trabecula formation (GO:0060346)3.91813200
26cranial suture morphogenesis (GO:0060363)3.90520364
27nuclear pore organization (GO:0006999)3.90484651
28regulation of chondrocyte differentiation (GO:0032330)3.84665099
29hippo signaling (GO:0035329)3.83189519
30sequestering of extracellular ligand from receptor (GO:0035581)3.82361669
31anterior/posterior axis specification, embryo (GO:0008595)3.81473176
32negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.78967968
33cell migration involved in heart development (GO:0060973)3.73915320
34regulation of cartilage development (GO:0061035)3.71810348
35regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.71689438
36hindlimb morphogenesis (GO:0035137)3.67423748
37cellular protein complex localization (GO:0034629)3.66765969
38embryonic cranial skeleton morphogenesis (GO:0048701)3.65287347
39endocardial cushion development (GO:0003197)3.65070567
40regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.64385922
41negative regulation of myoblast differentiation (GO:0045662)3.63808126
42outer ear morphogenesis (GO:0042473)3.60267546
43collagen fibril organization (GO:0030199)3.60227694
44neuron projection extension involved in neuron projection guidance (GO:1902284)3.60091628
45axon extension involved in axon guidance (GO:0048846)3.60091628
46artery development (GO:0060840)3.55345304
47nuclear pore complex assembly (GO:0051292)3.55143440
48positive regulation of mesenchymal cell proliferation (GO:0002053)3.52929298
49negative regulation of axon extension involved in axon guidance (GO:0048843)3.52439515
50regulation of heart morphogenesis (GO:2000826)3.49015448
51craniofacial suture morphogenesis (GO:0097094)3.44484290
52neural crest cell development (GO:0014032)3.41663753
53* appendage morphogenesis (GO:0035107)3.41442872
54* limb morphogenesis (GO:0035108)3.41442872
55regulation of transforming growth factor beta2 production (GO:0032909)3.41415716
56negative regulation of chondrocyte differentiation (GO:0032331)3.40686175
57embryonic process involved in female pregnancy (GO:0060136)3.33723850
58regulation of organ formation (GO:0003156)3.28145776
59polarized epithelial cell differentiation (GO:0030859)3.24799847
60negative regulation of catenin import into nucleus (GO:0035414)3.24486837
61regulation of mesenchymal cell proliferation (GO:0010464)3.24005651
62muscle cell fate commitment (GO:0042693)3.23775924
63negative regulation of mRNA processing (GO:0050686)3.22749437
64positive regulation of epithelial to mesenchymal transition (GO:0010718)3.20784769
65kidney mesenchyme development (GO:0072074)3.20771679
66mesenchymal-epithelial cell signaling (GO:0060638)3.20633697
67embryonic hindlimb morphogenesis (GO:0035116)3.19345678
68cranial nerve morphogenesis (GO:0021602)3.18021755
69* embryonic appendage morphogenesis (GO:0035113)3.17690973
70* embryonic limb morphogenesis (GO:0030326)3.17690973
71pericardium development (GO:0060039)3.16979348
72middle ear morphogenesis (GO:0042474)3.16874133
73cell surface receptor signaling pathway involved in heart development (GO:0061311)3.14358943
74notochord development (GO:0030903)3.13454343
75epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)3.13265419
76paraxial mesoderm development (GO:0048339)3.10697566
77intestinal epithelial cell development (GO:0060576)3.10070800
78Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.09995901
79positive regulation of transcription from RNA polymerase III promoter (GO:0045945)3.09699978
80ventricular septum morphogenesis (GO:0060412)3.09490319
81regulation of fatty acid beta-oxidation (GO:0031998)3.09308120
82regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)3.09280559
83regulation of mammary gland epithelial cell proliferation (GO:0033599)3.09050783
84extracellular matrix assembly (GO:0085029)3.08742202
85desmosome organization (GO:0002934)3.06645485
86negative regulation of DNA repair (GO:0045738)3.06125285
87mammary gland development (GO:0030879)3.05986584
88atrioventricular valve morphogenesis (GO:0003181)3.03369520
89chondrocyte development (GO:0002063)3.03140750
90positive regulation of fatty acid beta-oxidation (GO:0032000)3.03033511
91* reproductive system development (GO:0061458)3.02639932
92adherens junction assembly (GO:0034333)3.02330935
93negative regulation of embryonic development (GO:0045992)3.01767218
94mesenchymal cell development (GO:0014031)3.01325322
95G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.00252119
96regulation of establishment of planar polarity (GO:0090175)2.99456129
97embryonic camera-type eye morphogenesis (GO:0048596)2.98798719
98mesenchyme morphogenesis (GO:0072132)2.98759201
99body morphogenesis (GO:0010171)2.98677929
100mitotic sister chromatid cohesion (GO:0007064)2.98465935
101metanephric mesenchyme development (GO:0072075)2.98352579
102regulation of translational termination (GO:0006449)2.97520715
103eyelid development in camera-type eye (GO:0061029)2.97479234
104dorsal/ventral axis specification (GO:0009950)2.93977690
105trophectodermal cell differentiation (GO:0001829)2.92967995
106cartilage morphogenesis (GO:0060536)2.92554132
107cardiac septum morphogenesis (GO:0060411)2.88018172
108protein complex localization (GO:0031503)2.87343464
109cochlea morphogenesis (GO:0090103)2.86641909
110negative regulation of muscle cell differentiation (GO:0051148)2.85731971
111establishment of tissue polarity (GO:0007164)2.85450069
112establishment of planar polarity (GO:0001736)2.85450069
113positive regulation of smoothened signaling pathway (GO:0045880)2.83441284
114regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.82734851
115organ formation (GO:0048645)2.81279406
116basement membrane organization (GO:0071711)2.81009207
117cell proliferation involved in metanephros development (GO:0072203)2.80027232
118negative regulation of axon guidance (GO:1902668)2.79774903
119myoblast migration (GO:0051451)2.79201061
120protein heterotrimerization (GO:0070208)2.78811188
121smooth muscle tissue development (GO:0048745)2.78165892
122embryonic skeletal system morphogenesis (GO:0048704)2.76491666
123face development (GO:0060324)2.75802570
124atrial septum morphogenesis (GO:0060413)2.75160195
125embryonic organ morphogenesis (GO:0048562)2.74931172
126negative regulation of skeletal muscle tissue development (GO:0048642)2.74436784
127regulation of cardioblast differentiation (GO:0051890)2.73525826
128negative regulation of cartilage development (GO:0061037)2.72661792
129negative regulation of vascular permeability (GO:0043116)2.72258967
130UDP-N-acetylglucosamine metabolic process (GO:0006047)2.72127146
131non-canonical Wnt signaling pathway (GO:0035567)2.72115310
132negative regulation of mRNA metabolic process (GO:1903312)2.72066904
133negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)2.71688285
134mitotic chromosome condensation (GO:0007076)2.71170690
135* genitalia development (GO:0048806)2.71020708
136regulation of secondary heart field cardioblast proliferation (GO:0003266)2.70564808
137regulation of cardioblast proliferation (GO:0003264)2.70564808
138metanephros development (GO:0001656)2.70221457
139regulation of mitotic spindle organization (GO:0060236)2.69742184
140embryonic eye morphogenesis (GO:0048048)2.69303249
141skeletal system morphogenesis (GO:0048705)2.69283863
142epithelial to mesenchymal transition (GO:0001837)2.67160498
143peripheral nervous system neuron development (GO:0048935)2.66491534
144epithelial cell differentiation involved in prostate gland development (GO:0060742)2.65740074
145histone-serine phosphorylation (GO:0035404)2.65139427
146negative chemotaxis (GO:0050919)2.64306018
147negative regulation of RNA splicing (GO:0033119)2.64226216
148insulin-like growth factor receptor signaling pathway (GO:0048009)2.63727807
149cell migration involved in sprouting angiogenesis (GO:0002042)2.62790759
150DNA unwinding involved in DNA replication (GO:0006268)2.59726151
151developmental induction (GO:0031128)2.58160267
152pore complex assembly (GO:0046931)2.56154801
153negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518)2.55012837
154positive regulation of fatty acid oxidation (GO:0046321)2.54875272
155negative regulation of fatty acid transport (GO:2000192)2.52645249
156heterochromatin organization (GO:0070828)2.51393113
157muscle cell migration (GO:0014812)2.49184640
158folic acid metabolic process (GO:0046655)2.48268695
159cell-substrate adherens junction assembly (GO:0007045)2.47606849
160focal adhesion assembly (GO:0048041)2.47606849
161negative regulation of cell fate specification (GO:0009996)2.46770530
162vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.46551159
163embryonic heart tube development (GO:0035050)2.45577496
164cell-cell signaling involved in cell fate commitment (GO:0045168)2.43415718

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.57691446
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.87681749
3* RARG_19884340_ChIP-ChIP_MEFs_Mouse3.88949431
4TRIM28_21343339_ChIP-Seq_HEK293_Human3.86022711
5CDX2_19796622_ChIP-Seq_MESCs_Mouse2.80302141
6TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.67971924
7WT1_19549856_ChIP-ChIP_CCG9911_Human2.67889633
8TP63_19390658_ChIP-ChIP_HaCaT_Human2.65341441
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.52662749
10MYC_18555785_ChIP-Seq_MESCs_Mouse2.46268411
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.45327059
12CLOCK_20551151_ChIP-Seq_293T_Human2.43277631
13EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.40761536
14SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.35570007
15WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.33290809
16SALL1_21062744_ChIP-ChIP_HESCs_Human2.26796212
17PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.22955457
18CDX2_20551321_ChIP-Seq_CACO-2_Human2.16664984
19XRN2_22483619_ChIP-Seq_HELA_Human2.14305790
20ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.07302919
21STAT6_21828071_ChIP-Seq_BEAS2B_Human2.04801999
22HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.03280984
23KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.02612504
24* TP53_20018659_ChIP-ChIP_R1E_Mouse2.01266531
25ZNF263_19887448_ChIP-Seq_K562_Human2.00037209
26ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.92108101
27AR_21909140_ChIP-Seq_LNCAP_Human1.91837889
28PKCTHETA_26484144_Chip-Seq_BREAST_Human1.91798179
29* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.88438300
30* CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.86751930
31HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.86362895
32NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.85954621
33ESR1_20079471_ChIP-ChIP_T-47D_Human1.84030077
34HIF1A_21447827_ChIP-Seq_MCF-7_Human1.83507092
35E2F1_21310950_ChIP-Seq_MCF-7_Human1.82129881
36KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.81213281
37TTF2_22483619_ChIP-Seq_HELA_Human1.80530449
38E2F4_17652178_ChIP-ChIP_JURKAT_Human1.78249253
39BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.77614151
40KDM5A_27292631_Chip-Seq_BREAST_Human1.77287021
41* EED_16625203_ChIP-ChIP_MESCs_Mouse1.76345431
42* SOX2_20726797_ChIP-Seq_SW620_Human1.76097356
43* VDR_21846776_ChIP-Seq_THP-1_Human1.75688850
44CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.75216657
45DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.73956529
46TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.72726445
47CJUN_26792858_Chip-Seq_BT549_Human1.71041389
48ISL1_27105846_Chip-Seq_CPCs_Mouse1.68495156
49ESR2_21235772_ChIP-Seq_MCF-7_Human1.67777873
50CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.64875894
51ZFX_18555785_ChIP-Seq_MESCs_Mouse1.62864998
52RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.62776163
53FOXM1_23109430_ChIP-Seq_U2OS_Human1.61825610
54SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.61745139
55SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.61745139
56DCP1A_22483619_ChIP-Seq_HELA_Human1.60865887
57TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.59540340
58* SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.58102228
59SOX2_27498859_Chip-Seq_STOMACH_Mouse1.57831764
60MYC_19030024_ChIP-ChIP_MESCs_Mouse1.57729720
61SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.57534752
62ZNF217_24962896_ChIP-Seq_MCF-7_Human1.56391771
63MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.55560380
64PPAR_26484153_Chip-Seq_NCI-H1993_Human1.55044214
65EGR1_19374776_ChIP-ChIP_THP-1_Human1.53739992
66* EZH2_18974828_ChIP-Seq_MESCs_Mouse1.53614586
67* RNF2_18974828_ChIP-Seq_MESCs_Mouse1.53614586
68TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.53110459
69BRD4_25478319_ChIP-Seq_HGPS_Human1.51302534
70* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.50758837
71UBF1/2_26484160_Chip-Seq_HMECs_Human1.50549267
72TCF3_18692474_ChIP-Seq_MEFs_Mouse1.49465431
73ELK3_25401928_ChIP-Seq_HUVEC_Human1.48952116
74* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.46553621
75EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.44820796
76P300_27058665_Chip-Seq_ZR-75-30cells_Human1.43839296
77EP300_21415370_ChIP-Seq_HL-1_Mouse1.43542263
78GATA6_25053715_ChIP-Seq_YYC3_Human1.43427172
79ESR1_15608294_ChIP-ChIP_MCF-7_Human1.43024153
80ESR1_21235772_ChIP-Seq_MCF-7_Human1.42233023
81ZFP281_18757296_ChIP-ChIP_E14_Mouse1.41464706
82NRF2_20460467_ChIP-Seq_MEFs_Mouse1.41461987
83NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.41461987
84CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.40564896
85MYC_18358816_ChIP-ChIP_MESCs_Mouse1.40380209
86PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.39583862
87* EZH2_27304074_Chip-Seq_ESCs_Mouse1.37737002
88RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.37346751
89* SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.37300162
90NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.36572059
91* JARID2_20075857_ChIP-Seq_MESCs_Mouse1.36093703
92* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.34912996
93ZFP281_27345836_Chip-Seq_ESCs_Mouse1.34573855
94POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.33706222
95CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.33149235
96GATA4_25053715_ChIP-Seq_YYC3_Human1.33078202
97RACK7_27058665_Chip-Seq_MCF-7_Human1.32571099
98YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.32247896
99ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.32246011
100CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.32221085
101FOXO3_23340844_ChIP-Seq_DLD1_Human1.31089365
102KLF4_18555785_ChIP-Seq_MESCs_Mouse1.29308065
103SALL4_18804426_ChIP-ChIP_XEN_Mouse1.29187695
104MYC_19079543_ChIP-ChIP_MESCs_Mouse1.29094458
105ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.28384659
106SMAD_19615063_ChIP-ChIP_OVARY_Human1.27896752
107ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.27880941
108SMC1_22415368_ChIP-Seq_MEFs_Mouse1.27489205
109FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.27094700
110* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.27045637
111* SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.27031884
112DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.26502190
113TP53_16413492_ChIP-PET_HCT116_Human1.25850457
114ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.25796486
115STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.24896475
116MYCN_18555785_ChIP-Seq_MESCs_Mouse1.24257276
117PIAS1_25552417_ChIP-Seq_VCAP_Human1.24034380
118MYC_22102868_ChIP-Seq_BL_Human1.22709843
119DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.21919196
120CREB1_15753290_ChIP-ChIP_HEK293T_Human1.21130077
121* CBX2_27304074_Chip-Seq_ESCs_Mouse1.21058360
122CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.20294009
123ATF3_27146783_Chip-Seq_COLON_Human1.20004110
124ZNF274_21170338_ChIP-Seq_K562_Hela1.19371021
125NELFA_20434984_ChIP-Seq_ESCs_Mouse1.18700109
126* RING1B_27294783_Chip-Seq_NPCs_Mouse1.18450264
127TCF4_18268006_ChIP-ChIP_LS174T_Human1.18068180
128KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.17113411
129EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.17061715
130PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.16812281
131EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.16297846
132TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.14324979
133CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.13742373
134* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.13009268
135MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.10941218
136CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.10932931
137PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.10199459
138KLF5_25053715_ChIP-Seq_YYC3_Human1.09873865
139* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.08320160
140CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.07392218
141CHD1_26751641_Chip-Seq_LNCaP_Human1.07190955
142* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.06554771
143KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.05316335
144KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.05316335
145KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.05316335
146RUNX1_27514584_Chip-Seq_MCF-7_Human1.04252945
147FOXM1_26456572_ChIP-Seq_MCF-7_Human1.04184225
148SOX9_24532713_ChIP-Seq_HFSC_Mouse1.04122975
149* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03176646
150GABP_19822575_ChIP-Seq_HepG2_Human1.00390953
151KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.99177602
152CREB1_26743006_Chip-Seq_LNCaP_Human0.97630866
153TP53_22127205_ChIP-Seq_IMR90_Human0.97271973

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009053_abnormal_anal_canal7.37533774
2MP0008438_abnormal_cutaneous_collagen4.08426962
3MP0002009_preneoplasia3.79395703
4MP0003705_abnormal_hypodermis_morpholog3.76536489
5MP0005503_abnormal_tendon_morphology3.28543281
6MP0010030_abnormal_orbit_morphology2.96206918
7MP0009250_abnormal_appendicular_skeleto2.86391540
8MP0003385_abnormal_body_wall2.73641246
9MP0010234_abnormal_vibrissa_follicle2.72862616
10MP0003283_abnormal_digestive_organ2.66655440
11* MP0005187_abnormal_penis_morphology2.65240567
12MP0005275_abnormal_skin_tensile2.55583554
13* MP0003937_abnormal_limbs/digits/tail_de2.48325600
14* MP0000537_abnormal_urethra_morphology2.47751343
15MP0006054_spinal_hemorrhage2.47019319
16MP0002932_abnormal_joint_morphology2.21268846
17MP0003122_maternal_imprinting2.16533632
18MP0001346_abnormal_lacrimal_gland2.13164315
19MP0003123_paternal_imprinting2.12082123
20MP0002234_abnormal_pharynx_morphology2.12058453
21MP0004264_abnormal_extraembryonic_tissu2.06574396
22MP0010352_gastrointestinal_tract_polyps2.04180927
23MP0009384_cardiac_valve_regurgitation2.03624574
24MP0002282_abnormal_trachea_morphology1.96997534
25MP0000462_abnormal_digestive_system1.87809880
26MP0003693_abnormal_embryo_hatching1.86564187
27MP0003111_abnormal_nucleus_morphology1.83425190
28MP0004185_abnormal_adipocyte_glucose1.81243466
29MP0000534_abnormal_ureter_morphology1.81010003
30MP0000767_abnormal_smooth_muscle1.71303316
31MP0010094_abnormal_chromosome_stability1.67211185
32MP0004272_abnormal_basement_membrane1.67141786
33MP0005508_abnormal_skeleton_morphology1.65943297
34MP0002877_abnormal_melanocyte_morpholog1.64095478
35MP0000733_abnormal_muscle_development1.63486181
36* MP0002115_abnormal_skeleton_extremities1.63054700
37MP0001849_ear_inflammation1.60272968
38MP0000003_abnormal_adipose_tissue1.55250843
39MP0003941_abnormal_skin_development1.54483618
40MP0001661_extended_life_span1.54058179
41* MP0003942_abnormal_urinary_system1.53229383
42MP0003077_abnormal_cell_cycle1.53173791
43MP0005248_abnormal_Harderian_gland1.50820459
44MP0003279_aneurysm1.50170397
45* MP0002109_abnormal_limb_morphology1.47672466
46* MP0000516_abnormal_urinary_system1.45396812
47* MP0005367_renal/urinary_system_phenotyp1.45396812
48MP0005623_abnormal_meninges_morphology1.45322834
49MP0001299_abnormal_eye_distance/1.40041116
50MP0001958_emphysema1.39786423
51MP0002249_abnormal_larynx_morphology1.39253058
52MP0008932_abnormal_embryonic_tissue1.38279391
53MP0003567_abnormal_fetal_cardiomyocyte1.38032625
54MP0002166_altered_tumor_susceptibility1.36885086
55MP0003121_genomic_imprinting1.36843910
56MP0000428_abnormal_craniofacial_morphol1.35006554
57MP0000163_abnormal_cartilage_morphology1.33184219
58MP0003755_abnormal_palate_morphology1.32172935
59MP0005257_abnormal_intraocular_pressure1.32133499
60MP0008057_abnormal_DNA_replication1.31885221
61MP0000566_synostosis1.30705776
62MP0000049_abnormal_middle_ear1.27972354
63MP0004957_abnormal_blastocyst_morpholog1.24470517
64MP0002114_abnormal_axial_skeleton1.22603064
65MP0002113_abnormal_skeleton_development1.20959095
66MP0002060_abnormal_skin_morphology1.20309777
67MP0003115_abnormal_respiratory_system1.19645068
68MP0002896_abnormal_bone_mineralization1.16283603
69MP0004858_abnormal_nervous_system1.14451019
70MP0000350_abnormal_cell_proliferation1.13197298
71MP0000751_myopathy1.12055235
72MP0003935_abnormal_craniofacial_develop1.11183151
73MP0001730_embryonic_growth_arrest1.10050346
74MP0005670_abnormal_white_adipose1.08067796
75MP0005076_abnormal_cell_differentiation1.06985804
76MP0000762_abnormal_tongue_morphology1.05659510
77MP0010678_abnormal_skin_adnexa1.05313549
78MP0008961_abnormal_basal_metabolism1.05177370
79MP0005023_abnormal_wound_healing1.05069507
80MP0002111_abnormal_tail_morphology1.03873148
81MP0001879_abnormal_lymphatic_vessel1.03360447
82MP0005645_abnormal_hypothalamus_physiol1.01994943
83* MP0000477_abnormal_intestine_morphology1.00561343
84MP0000759_abnormal_skeletal_muscle1.00127107
85MP0002116_abnormal_craniofacial_bone0.99893739
86MP0003984_embryonic_growth_retardation0.99350610
87MP0005389_reproductive_system_phenotype0.98787982
88MP0004036_abnormal_muscle_relaxation0.96909435
89MP0010307_abnormal_tumor_latency0.96758774
90MP0003091_abnormal_cell_migration0.96420117
91MP0000432_abnormal_head_morphology0.96419443
92MP0001270_distended_abdomen0.96328734
93MP0008007_abnormal_cellular_replicative0.96123607
94MP0003119_abnormal_digestive_system0.92973352
95MP0002233_abnormal_nose_morphology0.92516472
96MP0002085_abnormal_embryonic_tissue0.92354800
97MP0004197_abnormal_fetal_growth/weight/0.91177454
98MP0002088_abnormal_embryonic_growth/wei0.90942577
99MP0002938_white_spotting0.90533027
100MP0000647_abnormal_sebaceous_gland0.89054132
101* MP0001664_abnormal_digestion0.88667313
102MP0010368_abnormal_lymphatic_system0.87089518
103MP0001286_abnormal_eye_development0.86367123
104MP0009697_abnormal_copulation0.85529121
105MP0002006_tumorigenesis0.82940189
106MP0009780_abnormal_chondrocyte_physiolo0.82735426
107MP0000013_abnormal_adipose_tissue0.82650599
108MP0000681_abnormal_thyroid_gland0.82312010
109MP0000678_abnormal_parathyroid_gland0.81829854
110MP0002396_abnormal_hematopoietic_system0.81669594
111MP0002177_abnormal_outer_ear0.81122164
112* MP0002080_prenatal_lethality0.80433734
113MP0002084_abnormal_developmental_patter0.80286295
114* MP0003315_abnormal_perineum_morphology0.79363318
115MP0004134_abnormal_chest_morphology0.79026961
116* MP0001697_abnormal_embryo_size0.78613427
117MP0001672_abnormal_embryogenesis/_devel0.78566987
118MP0005380_embryogenesis_phenotype0.78566987
119MP0005375_adipose_tissue_phenotype0.78253474
120MP0002108_abnormal_muscle_morphology0.77933865
121* MP0000538_abnormal_urinary_bladder0.76258674
122MP0010386_abnormal_urinary_bladder0.74935438
123MP0005167_abnormal_blood-brain_barrier0.72610122
124MP0003453_abnormal_keratinocyte_physiol0.70362585
125MP0000467_abnormal_esophagus_morphology0.69657841
126* MP0002925_abnormal_cardiovascular_devel0.69361373
127MP0000383_abnormal_hair_follicle0.69272511
128MP0000579_abnormal_nail_morphology0.66535237
129MP0003566_abnormal_cell_adhesion0.66034359
130MP0002295_abnormal_pulmonary_circulatio0.65272962
131MP0005390_skeleton_phenotype0.64728546
132* MP0002086_abnormal_extraembryonic_tissu0.64656147
133MP0005381_digestive/alimentary_phenotyp0.64515761
134MP0003938_abnormal_ear_development0.63176491
135MP0002160_abnormal_reproductive_system0.61540776
136MP0003936_abnormal_reproductive_system0.59574753
137MP0002697_abnormal_eye_size0.58406777
138MP0004233_abnormal_muscle_weight0.57733765
139MP0002092_abnormal_eye_morphology0.57535001
140MP0001340_abnormal_eyelid_morphology0.57349854
141* MP0001614_abnormal_blood_vessel0.57231856
142MP0003300_gastrointestinal_ulcer0.57116269

Predicted human phenotypes

RankGene SetZ-score
1Short middle phalanx of the 5th finger (HP:0004220)6.36802160
2Abnormality of the phalanges of the hallux (HP:0010057)5.57303473
3Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)5.21611401
4Absent phalangeal crease (HP:0006109)5.21262125
5Abnormality of the 4th metacarpal (HP:0010012)5.09531481
6Abnormality of the middle phalanges of the toes (HP:0010183)4.99228623
7Sparse lateral eyebrow (HP:0005338)4.88100307
8Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)4.73110523
9Abnormality of the middle phalanx of the 5th finger (HP:0004219)4.68782343
10Abnormality of the distal phalanx of the thumb (HP:0009617)4.37350920
11Broad distal phalanx of finger (HP:0009836)4.35584214
12Abnormal finger flexion creases (HP:0006143)4.32504695
13Abnormality of the phalanges of the 5th finger (HP:0004213)4.30983667
14Symphalangism affecting the phalanges of the hand (HP:0009773)4.26433104
15Mesomelia (HP:0003027)3.90031892
16Abnormality of the distal phalanges of the toes (HP:0010182)3.84990912
17* Short 5th finger (HP:0009237)3.83810493
18Aplasia of the musculature (HP:0100854)3.78298016
19Abnormal umbilical cord blood vessels (HP:0011403)3.73691893
20Single umbilical artery (HP:0001195)3.73691893
21Abnormality of the fetal cardiovascular system (HP:0010948)3.73691893
22Protrusio acetabuli (HP:0003179)3.59184418
23Shallow orbits (HP:0000586)3.58283483
24* Aplasia/Hypoplasia of the 5th finger (HP:0006262)3.51408388
25Premature rupture of membranes (HP:0001788)3.47436942
26* Abnormality of the 2nd finger (HP:0004100)3.36906750
27Anal stenosis (HP:0002025)3.28179284
28Aortic aneurysm (HP:0004942)3.27069256
29Aortic dissection (HP:0002647)3.24405359
30Partial duplication of the phalanx of hand (HP:0009999)3.20866587
31Breast hypoplasia (HP:0003187)3.20270104
32Esophageal atresia (HP:0002032)3.13502092
33* Short middle phalanx of finger (HP:0005819)3.08323852
34Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.04263414
35Short 4th metacarpal (HP:0010044)3.04263414
36* Ureteral stenosis (HP:0000071)2.98866914
37Lip pit (HP:0100267)2.97710871
38Broad thumb (HP:0011304)2.96420558
39Abnormality of the phalanges of the 2nd finger (HP:0009541)2.96329417
40Hallux valgus (HP:0001822)2.93706035
41* Deviation of the hallux (HP:0010051)2.91116661
42* Ureteral obstruction (HP:0006000)2.85382354
43Aplastic anemia (HP:0001915)2.83856678
44Shawl scrotum (HP:0000049)2.81847562
45Abnormal number of incisors (HP:0011064)2.81109723
46Short clavicles (HP:0000894)2.76835069
47Abnormality of the proximal phalanges of the hand (HP:0009834)2.74663671
48Radial bowing (HP:0002986)2.71347702
49Unilateral renal agenesis (HP:0000122)2.71099525
50Cutaneous finger syndactyly (HP:0010554)2.69527241
51Fibular aplasia (HP:0002990)2.68881165
52Deformed tarsal bones (HP:0008119)2.62695426
53Aplasia/Hypoplasia of the clavicles (HP:0006710)2.61849290
54Asymmetry of the thorax (HP:0001555)2.53949515
55Tracheal stenosis (HP:0002777)2.53426491
56Testicular atrophy (HP:0000029)2.52173719
57Broad toe (HP:0001837)2.44729439
58* Abnormality of the 1st metacarpal (HP:0010009)2.44610865
59Intestinal fistula (HP:0100819)2.43582407
60Atrophic scars (HP:0001075)2.43283896
61Narrow palate (HP:0000189)2.42473558
62Long clavicles (HP:0000890)2.42468613
63Abnormality of the umbilical cord (HP:0010881)2.42194334
64* Aplasia/Hypoplasia of the middle phalanges of the hand (HP:0009843)2.41247577
65* Abnormality of the middle phalanges of the hand (HP:0009833)2.39658470
66Reduced subcutaneous adipose tissue (HP:0003758)2.37954847
67Occipital encephalocele (HP:0002085)2.35429663
68Broad phalanges of the hand (HP:0009768)2.35379872
69Syringomyelia (HP:0003396)2.34286322
70Spinal cord lesions (HP:0100561)2.34286322
71Fragile skin (HP:0001030)2.33377961
72Wrist flexion contracture (HP:0001239)2.32829561
73Cutaneous syndactyly (HP:0012725)2.31324005
74Microglossia (HP:0000171)2.30706157
75Broad long bones (HP:0005622)2.30411415
76* Short hallux (HP:0010109)2.30349853
77Ulnar bowing (HP:0003031)2.29804730
78* Ulnar deviation of finger (HP:0009465)2.28782724
79Abnormality of the nasal septum (HP:0000419)2.27936089
80Broad phalanx (HP:0006009)2.27221746
81Short humerus (HP:0005792)2.24627879
82Hyperacusis (HP:0010780)2.23479949
83Broad finger (HP:0001500)2.23099576
84Broad metatarsal (HP:0001783)2.21633673
85Dysmetric saccades (HP:0000641)2.21602544
86Partial duplication of thumb phalanx (HP:0009944)2.20329487
87Preaxial foot polydactyly (HP:0001841)2.19200184
88* Carpal synostosis (HP:0009702)2.18837680
89* Aplasia/Hypoplasia of metatarsal bones (HP:0001964)2.16620599
90Ectopic kidney (HP:0000086)2.16284685
91Ankle contracture (HP:0006466)2.15650978
92Trismus (HP:0000211)2.14901518
93Coronal craniosynostosis (HP:0004440)2.14710583
94Short nail (HP:0001799)2.14408543
95Aplasia/Hypoplasia involving the musculature (HP:0001460)2.11474692
96* Short metatarsal (HP:0010743)2.11118623
97Aplasia/hypoplasia of the humerus (HP:0006507)2.10213633
98Bowed forearm bones (HP:0003956)2.09701455
99Bowing of the arm (HP:0006488)2.09701455
100Buphthalmos (HP:0000557)2.08800345
101Renal duplication (HP:0000075)2.07810225
102Increased number of teeth (HP:0011069)2.06874478
103Abnormality of the axillary hair (HP:0100134)2.06232412
104Abnormality of secondary sexual hair (HP:0009888)2.06232412
105Cervical subluxation (HP:0003308)2.05174575
106* Aplasia/Hypoplasia of the hallux (HP:0008362)2.04968815
107* Synostosis involving bones of the hand (HP:0004278)2.04831710
108Dilatation of the ascending aorta (HP:0005111)2.04622944
109Dislocated radial head (HP:0003083)2.03570394
110Absent radius (HP:0003974)2.02189972
111Hypoplastic toenails (HP:0001800)2.01972015
112Aplasia/Hypoplasia of the scapulae (HP:0006713)2.01745603
113Hypoplastic scapulae (HP:0000882)2.01745603
114Calcaneovalgus deformity (HP:0001848)1.98842688
115Mitral valve prolapse (HP:0001634)1.98702726
116Duplication of thumb phalanx (HP:0009942)1.98058758
117Facial cleft (HP:0002006)1.97677474
118Broad hallux (HP:0010055)1.97438546
119Urethral obstruction (HP:0000796)1.97165820
120Patellar dislocation (HP:0002999)1.95320315
121Rectal prolapse (HP:0002035)1.94018730
122* Deviation of the thumb (HP:0009603)1.93050419
123Wide anterior fontanel (HP:0000260)1.91752792
124Abnormality of the radial head (HP:0003995)1.91662344
125Peritonitis (HP:0002586)1.91576226
126Morphological abnormality of the middle ear (HP:0008609)1.91162519
127Flat acetabular roof (HP:0003180)1.90894860
128Bladder diverticulum (HP:0000015)1.90412244
129Midline defect of the nose (HP:0004122)1.89905217
130Long eyelashes (HP:0000527)1.89659288
131Periauricular skin pits (HP:0100277)1.88859048
132Preauricular pit (HP:0004467)1.88859048
133Neonatal short-limb short stature (HP:0008921)1.88794848
134* Septate vagina (HP:0001153)1.85864120
135Abnormality of the parietal bone (HP:0002696)1.85803559
136* Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.85703376
137* Short 1st metacarpal (HP:0010034)1.85703376
138Abnormality of the calcaneus (HP:0008364)1.85419158
139Type 1 muscle fiber predominance (HP:0003803)1.84409151
140Abnormality of the acetabulum (HP:0003170)1.84276372
141Infantile muscular hypotonia (HP:0008947)1.83463361
142Elbow flexion contracture (HP:0002987)1.82980352
143Absent forearm bone (HP:0003953)1.82546952
144Aplasia involving forearm bones (HP:0009822)1.82546952
145Abnormality of chromosome segregation (HP:0002916)1.82436031
146* Short phalanx of the thumb (HP:0009660)1.82104335
147Radioulnar synostosis (HP:0002974)1.81267019
148Spinal cord compression (HP:0002176)1.81007074
149Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.79008230
150* Proximal placement of thumb (HP:0009623)1.78211351
151Hypoplasia of the radius (HP:0002984)1.78091057
152Arterial tortuosity (HP:0005116)1.77532483
153Vascular tortuosity (HP:0004948)1.75552926
154Camptodactyly of toe (HP:0001836)1.75179232
155Abnormality of the intervertebral disk (HP:0005108)1.74547497
156Soft skin (HP:0000977)1.74118959
157Hypoplastic labia majora (HP:0000059)1.73688007
158Renal dysplasia (HP:0000110)1.71850094
159Overgrowth (HP:0001548)1.70686032
160Abnormality of the ischium (HP:0003174)1.70248425
161Microretrognathia (HP:0000308)1.66438967
162Osteolytic defects of the hand bones (HP:0009699)1.66036219
163Osteolytic defects of the phalanges of the hand (HP:0009771)1.66036219
164Hypoplastic ischia (HP:0003175)1.62317746
165Abnormal ventriculo-arterial connection (HP:0011563)1.61548898
166Transposition of the great arteries (HP:0001669)1.61548898
167Abnormal connection of the cardiac segments (HP:0011545)1.61548898

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS14.96857237
2DDR23.60865003
3TTN3.59932480
4LATS23.56804109
5CAMK1G3.34424602
6FRK3.30925125
7PDGFRA2.97954356
8EPHB22.87413548
9RIPK12.49258605
10PTK62.47225558
11TRIB32.27481193
12FER2.19220932
13IRAK32.07447602
14PKN21.88090804
15PIK3CA1.80990025
16BUB11.73065612
17STK31.72847274
18DMPK1.72737875
19PAK21.72079148
20MYLK1.70270247
21PRKD31.66203217
22MAP3K101.65207791
23MST1R1.64128014
24MET1.56903793
25SIK11.56110517
26PAK41.55150994
27PNCK1.52956914
28WNK41.49270621
29FGFR21.49140289
30EEF2K1.46937860
31AKT31.44144181
32STK38L1.44143069
33SMG11.43475456
34PTK21.42993742
35PRKD21.37730484
36ERN11.29372962
37NME21.29208726
38ERBB31.28120936
39MAP3K71.25864060
40LIMK11.23743245
41TESK11.23695124
42LRRK21.23488962
43FGFR11.22305088
44MKNK11.21370331
45LMTK21.17721360
46ERBB21.15864718
47CHEK21.13207483
48SRPK11.12811230
49MST41.07190006
50TGFBR11.03381351
51PIK3CG1.02876338
52PDGFRB1.01405431
53PTK2B0.95489364
54WEE10.94944036
55NEK90.94495861
56PAK30.91420001
57MAP3K80.88952942
58CDK60.88241835
59MAP2K20.86789423
60ACVR1B0.83166603
61BRSK10.81482421
62MAP2K10.81429925
63STK390.77042223
64MAPK110.75043157
65STK100.71672600
66TNK20.70748396
67MTOR0.70600574
68TTK0.70264140
69NUAK10.69981580
70CHEK10.68509450
71ROCK10.68230363
72ATR0.67891580
73BRD40.67854602
74PLK40.67834537
75PAK10.67714765
76SCYL20.67205162
77BMX0.66247038
78ICK0.64093362
79CDC70.62604758
80PRKAA10.60518816
81PHKG20.60026370
82PHKG10.60026370
83CDK120.58737004
84ERBB40.58432504
85TGFBR20.58153429
86MOS0.57524370
87TYRO30.57400599
88CDK90.56944749
89ROCK20.54906068
90PIM20.54766807
91ARAF0.51558586
92KSR10.51315372
93AURKA0.51270212
94NEK10.51164206
95RPS6KB20.51155711
96DYRK1B0.51149793
97RAF10.50563660
98CAMKK20.50543497
99CSNK1A1L0.48841871
100STK380.48824834
101CDK80.48577340
102PASK0.48266766
103TRPM70.47112542
104RPS6KL10.45394774
105RPS6KC10.45394774
106PRKCI0.45300219
107PRKG20.45245925
108MELK0.45168365
109CDK70.45068193
110NME10.44345826
111RPS6KA60.43892139
112WNK10.43735030
113KSR20.42873491
114TAOK10.42646847
115MKNK20.41777159
116STK240.41442522
117SRC0.40448809
118EPHA20.40012328
119CAMK40.39550803
120PRKD10.39469769
121CDK10.38663080
122CDK20.38559833
123CAMK1D0.37884984
124CAMK10.37844992
125IRAK20.37191890
126PBK0.35381322
127MAP3K30.35044312
128MAP2K30.34571254
129GSK3A0.34482064
130PDK20.34116056
131MAPK140.33755569
132BRAF0.33683261
133YES10.33513289
134MAPKAPK50.33008244
135EIF2AK10.32769000
136NEK20.32178374
137AURKB0.31896501
138PRKAA20.31507404
139RPS6KA40.31436095
140CSNK1G10.30967899
141TESK20.30784288
142PLK10.30587471
143BRSK20.28131308
144ADRBK10.27147472
145RET0.26763952
146ILK0.26663489
147MAP3K20.25026365
148PLK20.24986445

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009203.69829518
2Basal cell carcinoma_Homo sapiens_hsa052172.88735867
3Hippo signaling pathway_Homo sapiens_hsa043902.78423921
4TGF-beta signaling pathway_Homo sapiens_hsa043502.69168444
5Adherens junction_Homo sapiens_hsa045202.65492175
6DNA replication_Homo sapiens_hsa030302.60433781
7Hedgehog signaling pathway_Homo sapiens_hsa043402.49491314
8Sulfur relay system_Homo sapiens_hsa041222.43792911
9ECM-receptor interaction_Homo sapiens_hsa045122.43514214
10Proteoglycans in cancer_Homo sapiens_hsa052052.34561307
11One carbon pool by folate_Homo sapiens_hsa006702.26794333
12Focal adhesion_Homo sapiens_hsa045102.24647169
13Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.20985586
14Tight junction_Homo sapiens_hsa045302.19207506
152-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.07709391
16Bladder cancer_Homo sapiens_hsa052192.00153752
17Bacterial invasion of epithelial cells_Homo sapiens_hsa051002.00100418
18RNA transport_Homo sapiens_hsa030131.89344725
19Lysine degradation_Homo sapiens_hsa003101.86246951
20Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.79271857
21MicroRNAs in cancer_Homo sapiens_hsa052061.78292509
22Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.73395838
23Fatty acid biosynthesis_Homo sapiens_hsa000611.70693937
24Small cell lung cancer_Homo sapiens_hsa052221.66768590
25Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.66133582
26Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.61248797
27Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.59317286
28Spliceosome_Homo sapiens_hsa030401.56375885
29Chronic myeloid leukemia_Homo sapiens_hsa052201.55244864
30Thyroid cancer_Homo sapiens_hsa052161.54304524
31mRNA surveillance pathway_Homo sapiens_hsa030151.53187094
32Wnt signaling pathway_Homo sapiens_hsa043101.45347035
33Nucleotide excision repair_Homo sapiens_hsa034201.43988287
34Protein digestion and absorption_Homo sapiens_hsa049741.43945937
35Prostate cancer_Homo sapiens_hsa052151.43345451
36Cysteine and methionine metabolism_Homo sapiens_hsa002701.40083175
37Mismatch repair_Homo sapiens_hsa034301.39884272
38Leukocyte transendothelial migration_Homo sapiens_hsa046701.37289619
39Mineral absorption_Homo sapiens_hsa049781.36997151
40Pyrimidine metabolism_Homo sapiens_hsa002401.36289812
41Base excision repair_Homo sapiens_hsa034101.34201527
42Axon guidance_Homo sapiens_hsa043601.33262928
43Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.30437628
44Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.29271478
45Amoebiasis_Homo sapiens_hsa051461.27888799
46Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.26311147
47Selenocompound metabolism_Homo sapiens_hsa004501.26103512
48Melanogenesis_Homo sapiens_hsa049161.24333324
49Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.24135591
50Arginine biosynthesis_Homo sapiens_hsa002201.22378436
51AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.21772443
52Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.20057590
53Pathways in cancer_Homo sapiens_hsa052001.19223913
54Melanoma_Homo sapiens_hsa052181.18269991
55Endometrial cancer_Homo sapiens_hsa052131.17168105
56Colorectal cancer_Homo sapiens_hsa052101.17146759
57Renin-angiotensin system_Homo sapiens_hsa046141.16135834
58Biosynthesis of amino acids_Homo sapiens_hsa012301.14648837
59RNA polymerase_Homo sapiens_hsa030201.13628046
60Homologous recombination_Homo sapiens_hsa034401.12656270
61Dilated cardiomyopathy_Homo sapiens_hsa054141.10821802
62Vitamin B6 metabolism_Homo sapiens_hsa007501.09425061
63PI3K-Akt signaling pathway_Homo sapiens_hsa041511.08634402
64Regulation of actin cytoskeleton_Homo sapiens_hsa048101.07745800
65Thyroid hormone synthesis_Homo sapiens_hsa049181.07724379
66Pancreatic cancer_Homo sapiens_hsa052121.06401628
67Pyruvate metabolism_Homo sapiens_hsa006201.05620718
68Cell cycle_Homo sapiens_hsa041101.04982456
69Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.04355624
70Nitrogen metabolism_Homo sapiens_hsa009101.02237950
71Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.01518262
72Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.00705161
73Salmonella infection_Homo sapiens_hsa051321.00591815
74Non-homologous end-joining_Homo sapiens_hsa034500.99914997
75Rap1 signaling pathway_Homo sapiens_hsa040150.96048571
76Glioma_Homo sapiens_hsa052140.89796842
77p53 signaling pathway_Homo sapiens_hsa041150.89226590
78Vascular smooth muscle contraction_Homo sapiens_hsa042700.89136157
79Gap junction_Homo sapiens_hsa045400.86547279
80HTLV-I infection_Homo sapiens_hsa051660.85391785
81Viral myocarditis_Homo sapiens_hsa054160.85117565
82Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.83999305
83Basal transcription factors_Homo sapiens_hsa030220.82883684
84Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.82427151
85Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.79876727
86Shigellosis_Homo sapiens_hsa051310.78128985
87Viral carcinogenesis_Homo sapiens_hsa052030.77392814
88Transcriptional misregulation in cancer_Homo sapiens_hsa052020.76420375
89Circadian rhythm_Homo sapiens_hsa047100.75943729
90Estrogen signaling pathway_Homo sapiens_hsa049150.75760132
91N-Glycan biosynthesis_Homo sapiens_hsa005100.75735096
92Notch signaling pathway_Homo sapiens_hsa043300.73817199
93Cyanoamino acid metabolism_Homo sapiens_hsa004600.72205758
94mTOR signaling pathway_Homo sapiens_hsa041500.71782209
95Platelet activation_Homo sapiens_hsa046110.71585060
96Adipocytokine signaling pathway_Homo sapiens_hsa049200.71557900
97Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.69244188
98Systemic lupus erythematosus_Homo sapiens_hsa053220.68701858
99Purine metabolism_Homo sapiens_hsa002300.67365853
100Fanconi anemia pathway_Homo sapiens_hsa034600.66512309
101Malaria_Homo sapiens_hsa051440.64047996
102VEGF signaling pathway_Homo sapiens_hsa043700.63653786
103Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.63324475
104Non-small cell lung cancer_Homo sapiens_hsa052230.62724370
105Arginine and proline metabolism_Homo sapiens_hsa003300.61150867
106GnRH signaling pathway_Homo sapiens_hsa049120.58119579
107Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.57125954
108Dorso-ventral axis formation_Homo sapiens_hsa043200.56349667
109Central carbon metabolism in cancer_Homo sapiens_hsa052300.56208783
110Insulin resistance_Homo sapiens_hsa049310.56171873
111RNA degradation_Homo sapiens_hsa030180.53989938
112Hepatitis B_Homo sapiens_hsa051610.53042900
113Alcoholism_Homo sapiens_hsa050340.52210731
114Ribosome_Homo sapiens_hsa030100.52050720
115Choline metabolism in cancer_Homo sapiens_hsa052310.52032643
116Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.51623274
117AMPK signaling pathway_Homo sapiens_hsa041520.51424190
118Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.51086995
119Renal cell carcinoma_Homo sapiens_hsa052110.50452055
120Longevity regulating pathway - mammal_Homo sapiens_hsa042110.50281678
121Drug metabolism - other enzymes_Homo sapiens_hsa009830.50228910
122Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.49542442
123Oocyte meiosis_Homo sapiens_hsa041140.49371476
124FoxO signaling pathway_Homo sapiens_hsa040680.48796926
125Toxoplasmosis_Homo sapiens_hsa051450.48276217
126HIF-1 signaling pathway_Homo sapiens_hsa040660.48241197
127cGMP-PKG signaling pathway_Homo sapiens_hsa040220.44947940
128Type II diabetes mellitus_Homo sapiens_hsa049300.44925210
129Oxytocin signaling pathway_Homo sapiens_hsa049210.43346361
130Pancreatic secretion_Homo sapiens_hsa049720.42711331
131Neurotrophin signaling pathway_Homo sapiens_hsa047220.41402077
132ErbB signaling pathway_Homo sapiens_hsa040120.41107172
133Carbon metabolism_Homo sapiens_hsa012000.40311014
134Thyroid hormone signaling pathway_Homo sapiens_hsa049190.39954226
135Fat digestion and absorption_Homo sapiens_hsa049750.39916243
136TNF signaling pathway_Homo sapiens_hsa046680.39347344
137Fructose and mannose metabolism_Homo sapiens_hsa000510.38688370
138Ras signaling pathway_Homo sapiens_hsa040140.35816735
139Glucagon signaling pathway_Homo sapiens_hsa049220.34316772
140Insulin signaling pathway_Homo sapiens_hsa049100.34249227
141Ovarian steroidogenesis_Homo sapiens_hsa049130.34094681
142Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.31151658

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »