Rank | Gene Set | Z-score |
---|---|---|
1 | drug transmembrane transport (GO:0006855) | 7.57297698 |
2 | angiotensin maturation (GO:0002003) | 7.38516889 |
3 | aminoglycoside antibiotic metabolic process (GO:0030647) | 7.36248961 |
4 | urate metabolic process (GO:0046415) | 7.09747931 |
5 | intestinal absorption (GO:0050892) | 6.90896690 |
6 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 6.68812220 |
7 | phosphate ion transport (GO:0006817) | 6.52227096 |
8 | drug transport (GO:0015893) | 6.49639829 |
9 | excretion (GO:0007588) | 6.26530539 |
10 | lysine catabolic process (GO:0006554) | 6.21581841 |
11 | lysine metabolic process (GO:0006553) | 6.21581841 |
12 | positive regulation of respiratory burst (GO:0060267) | 5.87597928 |
13 | organic cation transport (GO:0015695) | 5.78790431 |
14 | quaternary ammonium group transport (GO:0015697) | 5.75278395 |
15 | renal absorption (GO:0070293) | 5.70822856 |
16 | phosphate ion transmembrane transport (GO:0035435) | 5.50253823 |
17 | positive regulation of guanylate cyclase activity (GO:0031284) | 5.28511132 |
18 | cellular ketone body metabolic process (GO:0046950) | 5.26178872 |
19 | response to mercury ion (GO:0046689) | 5.23357947 |
20 | epoxygenase P450 pathway (GO:0019373) | 5.10966774 |
21 | sulfur amino acid catabolic process (GO:0000098) | 4.90097516 |
22 | fat-soluble vitamin biosynthetic process (GO:0042362) | 4.85586113 |
23 | glyoxylate metabolic process (GO:0046487) | 4.80463254 |
24 | drug catabolic process (GO:0042737) | 4.76914003 |
25 | receptor guanylyl cyclase signaling pathway (GO:0007168) | 4.70296453 |
26 | positive regulation of pseudopodium assembly (GO:0031274) | 4.70182282 |
27 | amino-acid betaine transport (GO:0015838) | 4.67641974 |
28 | carnitine transport (GO:0015879) | 4.67641974 |
29 | glomerular filtration (GO:0003094) | 4.63176509 |
30 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 4.59747491 |
31 | phosphate ion homeostasis (GO:0055062) | 4.59735080 |
32 | trivalent inorganic anion homeostasis (GO:0072506) | 4.59735080 |
33 | exogenous drug catabolic process (GO:0042738) | 4.57530522 |
34 | regulation of cellular extravasation (GO:0002691) | 4.54452662 |
35 | nonribosomal peptide biosynthetic process (GO:0019184) | 4.54120280 |
36 | regulation of cGMP biosynthetic process (GO:0030826) | 4.53274061 |
37 | ketone body metabolic process (GO:1902224) | 4.50418707 |
38 | flavonoid metabolic process (GO:0009812) | 4.50266782 |
39 | cysteine metabolic process (GO:0006534) | 4.48526883 |
40 | tricarboxylic acid metabolic process (GO:0072350) | 4.46485837 |
41 | bile acid and bile salt transport (GO:0015721) | 4.45680590 |
42 | metanephric tubule development (GO:0072170) | 4.45622122 |
43 | metanephric nephron tubule development (GO:0072234) | 4.45622122 |
44 | homocysteine metabolic process (GO:0050667) | 4.45414609 |
45 | maintenance of gastrointestinal epithelium (GO:0030277) | 4.40637646 |
46 | ethanol oxidation (GO:0006069) | 4.33213502 |
47 | antibacterial humoral response (GO:0019731) | 4.27727995 |
48 | vitamin D metabolic process (GO:0042359) | 4.26036457 |
49 | regulation of vitamin metabolic process (GO:0030656) | 4.23315737 |
50 | renal filtration (GO:0097205) | 4.20918157 |
51 | regulation of pseudopodium assembly (GO:0031272) | 4.18662581 |
52 | short-chain fatty acid metabolic process (GO:0046459) | 4.17754034 |
53 | antimicrobial humoral response (GO:0019730) | 4.17147725 |
54 | urea cycle (GO:0000050) | 4.15598159 |
55 | actin filament depolymerization (GO:0030042) | 4.14749628 |
56 | glutathione biosynthetic process (GO:0006750) | 4.14285347 |
57 | regulation of bile acid biosynthetic process (GO:0070857) | 4.12014096 |
58 | metanephric nephron epithelium development (GO:0072243) | 4.07107504 |
59 | diacylglycerol metabolic process (GO:0046339) | 4.06017048 |
60 | oligosaccharide biosynthetic process (GO:0009312) | 4.00987480 |
61 | transcytosis (GO:0045056) | 3.98695996 |
62 | lipoprotein transport (GO:0042953) | 3.94391166 |
63 | desmosome organization (GO:0002934) | 3.93042144 |
64 | nephron tubule development (GO:0072080) | 3.91258730 |
65 | regulation of guanylate cyclase activity (GO:0031282) | 3.88811687 |
66 | urea metabolic process (GO:0019627) | 3.88348072 |
67 | metanephric epithelium development (GO:0072207) | 3.87681976 |
68 | sulfate transmembrane transport (GO:1902358) | 3.87253288 |
69 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.85978305 |
70 | aspartate family amino acid catabolic process (GO:0009068) | 3.79446532 |
71 | sulfur compound transport (GO:0072348) | 3.77081046 |
72 | modified amino acid transport (GO:0072337) | 3.73822245 |
73 | nucleoside diphosphate biosynthetic process (GO:0009133) | 3.73638217 |
74 | regulation of cGMP metabolic process (GO:0030823) | 3.69556487 |
75 | hormone catabolic process (GO:0042447) | 3.68954568 |
76 | * regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044) | 3.68897956 |
77 | * endocrine process (GO:0050886) | 3.68897956 |
78 | * regulation of systemic arterial blood pressure by hormone (GO:0001990) | 3.68897956 |
79 | positive regulation of glycoprotein biosynthetic process (GO:0010560) | 3.65923920 |
80 | ethanol metabolic process (GO:0006067) | 3.64659351 |
81 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 3.63884458 |
82 | fructose metabolic process (GO:0006000) | 3.62805853 |
83 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 3.62206497 |
84 | uronic acid metabolic process (GO:0006063) | 3.58085836 |
85 | glucuronate metabolic process (GO:0019585) | 3.58085836 |
86 | nitrogen cycle metabolic process (GO:0071941) | 3.51058440 |
87 | cellular glucuronidation (GO:0052695) | 3.50669652 |
88 | O-glycan processing (GO:0016266) | 3.47955267 |
89 | sodium ion homeostasis (GO:0055078) | 3.47927279 |
90 | * regulation of systemic arterial blood pressure (GO:0003073) | 3.47574723 |
91 | cellular response to vitamin D (GO:0071305) | 3.46715539 |
92 | GDP-mannose metabolic process (GO:0019673) | 3.46056552 |
93 | regulation of hydrogen peroxide metabolic process (GO:0010310) | 3.44846671 |
94 | positive regulation of glycoprotein metabolic process (GO:1903020) | 3.44604742 |
95 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 3.43643463 |
96 | bicarbonate transport (GO:0015701) | 3.43434719 |
97 | regulation of respiratory burst (GO:0060263) | 3.43322477 |
98 | digestive system process (GO:0022600) | 3.43272093 |
99 | renal tubule development (GO:0061326) | 3.42043331 |
100 | branched-chain amino acid metabolic process (GO:0009081) | 3.40377371 |
101 | auditory receptor cell differentiation (GO:0042491) | 3.39746874 |
102 | epithelial structure maintenance (GO:0010669) | 3.38790979 |
103 | fatty acid beta-oxidation (GO:0006635) | 3.38080868 |
104 | cellular modified amino acid catabolic process (GO:0042219) | 3.33856873 |
105 | nephron epithelium morphogenesis (GO:0072088) | 3.32838553 |
106 | nephron tubule morphogenesis (GO:0072078) | 3.32838553 |
107 | collecting duct development (GO:0072044) | 3.32756398 |
108 | vitamin transmembrane transport (GO:0035461) | 3.32645836 |
109 | proline metabolic process (GO:0006560) | 3.32088487 |
110 | carnitine transmembrane transport (GO:1902603) | 3.31815542 |
111 | toxin transport (GO:1901998) | 3.30876506 |
112 | fatty acid oxidation (GO:0019395) | 3.26043193 |
113 | labyrinthine layer development (GO:0060711) | 3.25686870 |
114 | glutathione metabolic process (GO:0006749) | 3.24348198 |
115 | glycoside metabolic process (GO:0016137) | 3.22648079 |
116 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.20848034 |
117 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 3.17997625 |
118 | lipid oxidation (GO:0034440) | 3.17892138 |
119 | response to growth hormone (GO:0060416) | 3.16164488 |
120 | hydrogen peroxide catabolic process (GO:0042744) | 3.15754372 |
121 | virion attachment to host cell (GO:0019062) | 3.15187463 |
122 | adhesion of symbiont to host cell (GO:0044650) | 3.15187463 |
123 | nephron epithelium development (GO:0072009) | 3.14930352 |
124 | sulfate transport (GO:0008272) | 3.14490689 |
125 | arginine metabolic process (GO:0006525) | 3.13552497 |
126 | vitamin transport (GO:0051180) | 3.13209018 |
127 | glycosphingolipid catabolic process (GO:0046479) | 3.12466355 |
128 | peptide biosynthetic process (GO:0043043) | 3.12032227 |
129 | valine metabolic process (GO:0006573) | 3.11144949 |
130 | * renal system process involved in regulation of blood volume (GO:0001977) | 3.08753773 |
131 | regulation of mesenchymal cell apoptotic process (GO:2001053) | 3.08596704 |
132 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 3.06997592 |
133 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 3.06997592 |
134 | glycolipid catabolic process (GO:0019377) | 3.06502570 |
135 | positive regulation of cGMP biosynthetic process (GO:0030828) | 3.05781803 |
136 | positive regulation of lipid catabolic process (GO:0050996) | 3.05068186 |
137 | peptide catabolic process (GO:0043171) | 3.04475216 |
138 | polyol transport (GO:0015791) | 3.04238418 |
139 | digestion (GO:0007586) | 3.03063895 |
140 | sperm capacitation (GO:0048240) | 3.02493018 |
141 | cellular response to vitamin (GO:0071295) | 3.00710753 |
142 | nucleotide-sugar biosynthetic process (GO:0009226) | 2.99401672 |
143 | 2-oxoglutarate metabolic process (GO:0006103) | 2.98711443 |
144 | peptide hormone processing (GO:0016486) | 2.97926734 |
145 | tricarboxylic acid cycle (GO:0006099) | 2.97332156 |
146 | carnitine shuttle (GO:0006853) | 2.96933948 |
147 | epithelial cell-cell adhesion (GO:0090136) | 2.96853722 |
148 | multicellular organismal water homeostasis (GO:0050891) | 2.96511491 |
149 | amino-acid betaine metabolic process (GO:0006577) | 2.94651942 |
150 | glutathione derivative biosynthetic process (GO:1901687) | 2.93332268 |
151 | glutathione derivative metabolic process (GO:1901685) | 2.93332268 |
152 | sphingomyelin metabolic process (GO:0006684) | 2.93209809 |
153 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 2.93111957 |
154 | glycerol metabolic process (GO:0006071) | 2.92974528 |
155 | glutamine family amino acid biosynthetic process (GO:0009084) | 2.92424970 |
156 | drug metabolic process (GO:0017144) | 2.91364004 |
157 | nephron tubule formation (GO:0072079) | 2.90558922 |
158 | serine family amino acid catabolic process (GO:0009071) | 2.90394214 |
159 | cGMP-mediated signaling (GO:0019934) | 2.88904352 |
160 | positive regulation of fatty acid oxidation (GO:0046321) | 2.88574061 |
161 | cellular response to pH (GO:0071467) | 2.88325784 |
162 | NADH metabolic process (GO:0006734) | 2.85541335 |
163 | regulation of cholesterol homeostasis (GO:2000188) | 2.84726291 |
164 | ATP synthesis coupled proton transport (GO:0015986) | 2.83967529 |
165 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.83967529 |
166 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.83257187 |
167 | L-phenylalanine metabolic process (GO:0006558) | 2.83257187 |
168 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.82910919 |
169 | plasma lipoprotein particle assembly (GO:0034377) | 2.82790651 |
170 | neurotransmitter biosynthetic process (GO:0042136) | 2.81001824 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 4.53504047 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.06724004 |
3 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 3.97390470 |
4 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 3.95710182 |
5 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.70272005 |
6 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 3.28527836 |
7 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 3.03786305 |
8 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.99498035 |
9 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.94651276 |
10 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.87737503 |
11 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.83161564 |
12 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 2.80231002 |
13 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 2.69208872 |
14 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.65168633 |
15 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.55150063 |
16 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.50915674 |
17 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.50548162 |
18 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.43691295 |
19 | GATA6_25053715_ChIP-Seq_YYC3_Human | 2.35906463 |
20 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 2.31525306 |
21 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.25248215 |
22 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 2.19636710 |
23 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.15212056 |
24 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 2.12285735 |
25 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.11852028 |
26 | GATA4_25053715_ChIP-Seq_YYC3_Human | 2.08747622 |
27 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 2.05335208 |
28 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.96228053 |
29 | * SOX2_20726797_ChIP-Seq_SW620_Human | 1.92954214 |
30 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.79841591 |
31 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.75905722 |
32 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.75881773 |
33 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.74310786 |
34 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.72037667 |
35 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.68043675 |
36 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.67078200 |
37 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.61754214 |
38 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.60871953 |
39 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.60856495 |
40 | * PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.57449150 |
41 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.55000111 |
42 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.47924047 |
43 | VDR_22108803_ChIP-Seq_LS180_Human | 1.47026497 |
44 | ATF3_27146783_Chip-Seq_COLON_Human | 1.46629346 |
45 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.45419438 |
46 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.44465365 |
47 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.43468929 |
48 | * TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.43351547 |
49 | * ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.40965824 |
50 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.39740234 |
51 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.38967966 |
52 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.38726696 |
53 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.36388588 |
54 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.33493873 |
55 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.33220677 |
56 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.31754181 |
57 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.30209252 |
58 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 1.30122036 |
59 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.28707738 |
60 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.27376813 |
61 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.25463870 |
62 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.23985198 |
63 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.23738730 |
64 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.21300174 |
65 | * RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.20299330 |
66 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.19668088 |
67 | * SA1_27219007_Chip-Seq_Bcells_Human | 1.19425969 |
68 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.17275348 |
69 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.16524060 |
70 | * OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.16425613 |
71 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 1.15637949 |
72 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.12697125 |
73 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.11777061 |
74 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.11253175 |
75 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.10913463 |
76 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.10846244 |
77 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.09368943 |
78 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.09361672 |
79 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.07591598 |
80 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.06633864 |
81 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.06619308 |
82 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.05962239 |
83 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.05803013 |
84 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.05504010 |
85 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.04317155 |
86 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.04287705 |
87 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.04246333 |
88 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.04082833 |
89 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.03671980 |
90 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.03609582 |
91 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.03493363 |
92 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.03445941 |
93 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.02965093 |
94 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.02657367 |
95 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.01400018 |
96 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.01375503 |
97 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.99045276 |
98 | KLF5_25053715_ChIP-Seq_YYC3_Human | 0.99035670 |
99 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.98609314 |
100 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.97880265 |
101 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.97201370 |
102 | P68_20966046_ChIP-Seq_HELA_Human | 0.97181830 |
103 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.97152773 |
104 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.96976596 |
105 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.96126571 |
106 | * RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.95803439 |
107 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.94348323 |
108 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.94250053 |
109 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.93061049 |
110 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.93001682 |
111 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.92805457 |
112 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.90636059 |
113 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.90284601 |
114 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.89893888 |
115 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.89623142 |
116 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 0.89457287 |
117 | ETS1_21867929_ChIP-Seq_TH2_Mouse | 0.88308250 |
118 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.85580763 |
119 | * GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.84937295 |
120 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.84864426 |
121 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.84402879 |
122 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.81502982 |
123 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.81482234 |
124 | * SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.81393225 |
125 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.81350692 |
126 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.80685775 |
127 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.79238355 |
128 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.78730327 |
129 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.78730327 |
130 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.78677200 |
131 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.78677200 |
132 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.78273667 |
133 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.78027194 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004043_abnormal_pH_regulation | 5.47326043 |
2 | MP0005360_urolithiasis | 4.86695812 |
3 | MP0009379_abnormal_foot_pigmentation | 3.76580529 |
4 | MP0004019_abnormal_vitamin_homeostasis | 3.68052945 |
5 | * MP0001765_abnormal_ion_homeostasis | 3.56901007 |
6 | MP0003283_abnormal_digestive_organ | 3.46679050 |
7 | * MP0009643_abnormal_urine_homeostasis | 3.28940194 |
8 | MP0005332_abnormal_amino_acid | 3.13879092 |
9 | MP0005377_hearing/vestibular/ear_phenot | 3.08152904 |
10 | MP0003878_abnormal_ear_physiology | 3.08152904 |
11 | MP0002139_abnormal_hepatobiliary_system | 3.05884768 |
12 | MP0010234_abnormal_vibrissa_follicle | 2.93115490 |
13 | MP0002138_abnormal_hepatobiliary_system | 2.88613600 |
14 | * MP0005636_abnormal_mineral_homeostasis | 2.86395817 |
15 | MP0004264_abnormal_extraembryonic_tissu | 2.83990370 |
16 | MP0003183_abnormal_peptide_metabolism | 2.83647418 |
17 | MP0008875_abnormal_xenobiotic_pharmacok | 2.58796420 |
18 | * MP0001756_abnormal_urination | 2.48789971 |
19 | MP0000537_abnormal_urethra_morphology | 2.43209210 |
20 | * MP0002136_abnormal_kidney_physiology | 2.39275937 |
21 | MP0004147_increased_porphyrin_level | 2.32710079 |
22 | MP0003195_calcinosis | 2.31640045 |
23 | MP0003252_abnormal_bile_duct | 2.29377396 |
24 | MP0001958_emphysema | 2.28566950 |
25 | MP0006054_spinal_hemorrhage | 2.27027301 |
26 | MP0000538_abnormal_urinary_bladder | 2.26994185 |
27 | MP0005409_darkened_coat_color | 2.18903889 |
28 | MP0000462_abnormal_digestive_system | 1.97084656 |
29 | MP0003868_abnormal_feces_composition | 1.96208577 |
30 | MP0003300_gastrointestinal_ulcer | 1.86160645 |
31 | MP0009840_abnormal_foam_cell | 1.84805522 |
32 | MP0003705_abnormal_hypodermis_morpholog | 1.83311199 |
33 | MP0003866_abnormal_defecation | 1.82349916 |
34 | MP0001188_hyperpigmentation | 1.82323071 |
35 | MP0005670_abnormal_white_adipose | 1.78299748 |
36 | MP0003315_abnormal_perineum_morphology | 1.78020052 |
37 | MP0001664_abnormal_digestion | 1.69551084 |
38 | MP0005381_digestive/alimentary_phenotyp | 1.67039263 |
39 | MP0001663_abnormal_digestive_system | 1.65852036 |
40 | MP0004858_abnormal_nervous_system | 1.63215390 |
41 | MP0004782_abnormal_surfactant_physiolog | 1.63212062 |
42 | MP0005365_abnormal_bile_salt | 1.52545453 |
43 | MP0001849_ear_inflammation | 1.50557373 |
44 | MP0005085_abnormal_gallbladder_physiolo | 1.48443038 |
45 | MP0008961_abnormal_basal_metabolism | 1.48179259 |
46 | MP0005058_abnormal_lysosome_morphology | 1.40603736 |
47 | MP0001666_abnormal_nutrient_absorption | 1.38123956 |
48 | MP0000566_synostosis | 1.38006173 |
49 | MP0010329_abnormal_lipoprotein_level | 1.35154457 |
50 | MP0009053_abnormal_anal_canal | 1.34055157 |
51 | MP0002089_abnormal_postnatal_growth/wei | 1.30231304 |
52 | MP0010155_abnormal_intestine_physiology | 1.29851614 |
53 | * MP0000477_abnormal_intestine_morphology | 1.24253198 |
54 | MP0002896_abnormal_bone_mineralization | 1.21799666 |
55 | MP0005167_abnormal_blood-brain_barrier | 1.21738672 |
56 | MP0003879_abnormal_hair_cell | 1.20256546 |
57 | MP0002254_reproductive_system_inflammat | 1.18727572 |
58 | MP0004885_abnormal_endolymph | 1.17770141 |
59 | MP0003693_abnormal_embryo_hatching | 1.16269690 |
60 | MP0004272_abnormal_basement_membrane | 1.15635454 |
61 | MP0010030_abnormal_orbit_morphology | 1.12131112 |
62 | MP0000490_abnormal_crypts_of | 1.11940754 |
63 | MP0005451_abnormal_body_composition | 1.10823879 |
64 | MP0002822_catalepsy | 1.10752384 |
65 | * MP0002135_abnormal_kidney_morphology | 1.06348492 |
66 | MP0002796_impaired_skin_barrier | 1.05499097 |
67 | MP0002928_abnormal_bile_duct | 1.05143723 |
68 | MP0010352_gastrointestinal_tract_polyps | 1.04146749 |
69 | MP0002098_abnormal_vibrissa_morphology | 1.02727553 |
70 | MP0000534_abnormal_ureter_morphology | 0.99636997 |
71 | MP0000678_abnormal_parathyroid_gland | 0.94692158 |
72 | MP0001764_abnormal_homeostasis | 0.93815725 |
73 | MP0000467_abnormal_esophagus_morphology | 0.92926019 |
74 | MP0003566_abnormal_cell_adhesion | 0.91411877 |
75 | MP0002282_abnormal_trachea_morphology | 0.90820119 |
76 | MP0008438_abnormal_cutaneous_collagen | 0.90065171 |
77 | MP0001485_abnormal_pinna_reflex | 0.84971586 |
78 | MP0001873_stomach_inflammation | 0.84515841 |
79 | MP0005319_abnormal_enzyme/_coenzyme | 0.81607238 |
80 | MP0000609_abnormal_liver_physiology | 0.81172628 |
81 | MP0005501_abnormal_skin_physiology | 0.80655726 |
82 | MP0002168_other_aberrant_phenotype | 0.79214358 |
83 | MP0002166_altered_tumor_susceptibility | 0.77782655 |
84 | MP0002115_abnormal_skeleton_extremities | 0.77102441 |
85 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.77089154 |
86 | MP0004484_altered_response_of | 0.76731671 |
87 | * MP0000230_abnormal_systemic_arterial | 0.75805657 |
88 | MP0002971_abnormal_brown_adipose | 0.74755598 |
89 | MP0000163_abnormal_cartilage_morphology | 0.74312778 |
90 | MP0008004_abnormal_stomach_pH | 0.74118153 |
91 | MP0010678_abnormal_skin_adnexa | 0.73932883 |
92 | MP0005666_abnormal_adipose_tissue | 0.71252409 |
93 | MP0002876_abnormal_thyroid_physiology | 0.71171538 |
94 | MP0005166_decreased_susceptibility_to | 0.69855655 |
95 | MP0001727_abnormal_embryo_implantation | 0.69821223 |
96 | MP0002009_preneoplasia | 0.66951900 |
97 | MP0008872_abnormal_physiological_respon | 0.66888472 |
98 | MP0002234_abnormal_pharynx_morphology | 0.66107391 |
99 | MP0002932_abnormal_joint_morphology | 0.65933397 |
100 | MP0001216_abnormal_epidermal_layer | 0.64220059 |
101 | MP0003186_abnormal_redox_activity | 0.63152139 |
102 | MP0003453_abnormal_keratinocyte_physiol | 0.62847217 |
103 | MP0005187_abnormal_penis_morphology | 0.61682357 |
104 | MP0001881_abnormal_mammary_gland | 0.61348482 |
105 | MP0009115_abnormal_fat_cell | 0.60806866 |
106 | MP0000465_gastrointestinal_hemorrhage | 0.59427695 |
107 | MP0003938_abnormal_ear_development | 0.59394471 |
108 | MP0004947_skin_inflammation | 0.58824347 |
109 | MP0003115_abnormal_respiratory_system | 0.58221905 |
110 | MP0000377_abnormal_hair_follicle | 0.57669683 |
111 | MP0002113_abnormal_skeleton_development | 0.56474142 |
112 | MP0005310_abnormal_salivary_gland | 0.56408674 |
113 | MP0003942_abnormal_urinary_system | 0.55868310 |
114 | MP0003638_abnormal_response/metabolism_ | 0.55614152 |
115 | MP0000681_abnormal_thyroid_gland | 0.55009057 |
116 | MP0005448_abnormal_energy_balance | 0.53251225 |
117 | MP0002006_tumorigenesis | 0.53007132 |
118 | MP0002249_abnormal_larynx_morphology | 0.52825822 |
119 | MP0001845_abnormal_inflammatory_respons | 0.52598581 |
120 | MP0003718_maternal_effect | 0.51746947 |
121 | MP0005375_adipose_tissue_phenotype | 0.51640748 |
122 | MP0001501_abnormal_sleep_pattern | 0.51570209 |
123 | MP0004742_abnormal_vestibular_system | 0.51427989 |
124 | MP0003122_maternal_imprinting | 0.50999334 |
125 | MP0003191_abnormal_cellular_cholesterol | 0.50857331 |
126 | MP0004233_abnormal_muscle_weight | 0.50531362 |
127 | MP0003806_abnormal_nucleotide_metabolis | 0.49825315 |
128 | * MP0009642_abnormal_blood_homeostasis | 0.49507671 |
129 | MP0005535_abnormal_body_temperature | 0.49167320 |
130 | MP0004270_analgesia | 0.48793504 |
131 | MP0003329_amyloid_beta_deposits | 0.47529348 |
132 | MP0003724_increased_susceptibility_to | 0.47464825 |
133 | MP0005084_abnormal_gallbladder_morpholo | 0.47280436 |
134 | MP0005257_abnormal_intraocular_pressure | 0.46906181 |
135 | MP0002111_abnormal_tail_morphology | 0.45658374 |
136 | MP0005220_abnormal_exocrine_pancreas | 0.45334353 |
137 | MP0003119_abnormal_digestive_system | 0.44709600 |
138 | MP0000762_abnormal_tongue_morphology | 0.44616929 |
139 | MP0002653_abnormal_ependyma_morphology | 0.44502827 |
140 | MP0001270_distended_abdomen | 0.44400453 |
141 | MP0000470_abnormal_stomach_morphology | 0.43816019 |
142 | MP0003941_abnormal_skin_development | 0.42769866 |
143 | MP0006036_abnormal_mitochondrial_physio | 0.41194942 |
144 | MP0002118_abnormal_lipid_homeostasis | 0.39912580 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperactive renin-angiotensin system (HP:0000841) | 8.40180214 |
2 | * Metabolic alkalosis (HP:0200114) | 7.62304910 |
3 | Abnormality of chloride homeostasis (HP:0011422) | 7.13921500 |
4 | Increased circulating renin level (HP:0000848) | 6.73765735 |
5 | Hypokalemic alkalosis (HP:0001949) | 6.60742146 |
6 | Hypomagnesemia (HP:0002917) | 6.17905238 |
7 | Polyuria (HP:0000103) | 5.73055354 |
8 | Gout (HP:0001997) | 5.60001983 |
9 | Abnormality of magnesium homeostasis (HP:0004921) | 5.48367078 |
10 | Hyperaldosteronism (HP:0000859) | 5.45962220 |
11 | Abnormal urine output (HP:0012590) | 5.35527911 |
12 | Abnormality of renal excretion (HP:0011036) | 5.04986216 |
13 | * Abnormality of renin-angiotensin system (HP:0000847) | 4.88233451 |
14 | Tetany (HP:0001281) | 4.66619989 |
15 | Renal salt wasting (HP:0000127) | 4.65098319 |
16 | Abnormal drinking behavior (HP:0030082) | 4.45581203 |
17 | Polydipsia (HP:0001959) | 4.45581203 |
18 | * Alkalosis (HP:0001948) | 4.38598919 |
19 | Proximal tubulopathy (HP:0000114) | 4.20899401 |
20 | Hyperuricemia (HP:0002149) | 4.15397746 |
21 | Increased purine levels (HP:0004368) | 4.15397746 |
22 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 3.73937538 |
23 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 3.73188975 |
24 | Hypercalciuria (HP:0002150) | 3.72321241 |
25 | * Hypokalemia (HP:0002900) | 3.59336632 |
26 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 3.52109730 |
27 | Abnormality of purine metabolism (HP:0004352) | 3.48660468 |
28 | Hyperglycinuria (HP:0003108) | 3.42723752 |
29 | Abnormality of vitamin B metabolism (HP:0004340) | 3.41891826 |
30 | Chronic diarrhea (HP:0002028) | 3.34068174 |
31 | Systemic lupus erythematosus (HP:0002725) | 3.26564418 |
32 | Generalized aminoaciduria (HP:0002909) | 3.21750733 |
33 | Pili torti (HP:0003777) | 3.18765274 |
34 | Confusion (HP:0001289) | 3.13899256 |
35 | Hemorrhage of the eye (HP:0011885) | 3.10671200 |
36 | Fat malabsorption (HP:0002630) | 3.05439829 |
37 | Abnormal tarsal ossification (HP:0008369) | 3.02066827 |
38 | Delayed epiphyseal ossification (HP:0002663) | 3.00440803 |
39 | Malnutrition (HP:0004395) | 2.99979896 |
40 | Abnormality of sodium homeostasis (HP:0010931) | 2.99761623 |
41 | Hyponatremia (HP:0002902) | 2.98817599 |
42 | Abnormality of vitamin metabolism (HP:0100508) | 2.89241008 |
43 | Hypotension (HP:0002615) | 2.86703136 |
44 | * Abnormality of potassium homeostasis (HP:0011042) | 2.85855878 |
45 | Renal tubular acidosis (HP:0001947) | 2.79429600 |
46 | Abnormality of proline metabolism (HP:0010907) | 2.79311924 |
47 | Hydroxyprolinuria (HP:0003080) | 2.79311924 |
48 | Congenital sensorineural hearing impairment (HP:0008527) | 2.78964171 |
49 | Abnormality of urine glucose concentration (HP:0011016) | 2.78623199 |
50 | Glycosuria (HP:0003076) | 2.78623199 |
51 | Villous atrophy (HP:0011473) | 2.72315699 |
52 | Abnormality of small intestinal villus morphology (HP:0011472) | 2.72315699 |
53 | Thin bony cortex (HP:0002753) | 2.71804833 |
54 | Dehydration (HP:0001944) | 2.71557266 |
55 | Abnormality of carpal bone ossification (HP:0006257) | 2.65496823 |
56 | Adrenal overactivity (HP:0002717) | 2.60683390 |
57 | Intrahepatic cholestasis (HP:0001406) | 2.59396672 |
58 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.59164124 |
59 | Abnormality of glycine metabolism (HP:0010895) | 2.59164124 |
60 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.51779196 |
61 | Ileus (HP:0002595) | 2.47849189 |
62 | Focal segmental glomerulosclerosis (HP:0000097) | 2.42855083 |
63 | Abnormal hair laboratory examination (HP:0003328) | 2.41795182 |
64 | Flattened epiphyses (HP:0003071) | 2.40951670 |
65 | Abnormal ossification of hand bones (HP:0005921) | 2.39027848 |
66 | Dicarboxylic aciduria (HP:0003215) | 2.38915849 |
67 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.38915849 |
68 | Abnormality of nucleobase metabolism (HP:0010932) | 2.38822526 |
69 | Nephrolithiasis (HP:0000787) | 2.37705681 |
70 | Nephrocalcinosis (HP:0000121) | 2.37180628 |
71 | Hyperphosphaturia (HP:0003109) | 2.34750826 |
72 | Widely patent fontanelles and sutures (HP:0004492) | 2.34483472 |
73 | Hyperkalemia (HP:0002153) | 2.30575189 |
74 | Ketoacidosis (HP:0001993) | 2.29904524 |
75 | Hypobetalipoproteinemia (HP:0003563) | 2.26949482 |
76 | Abnormal urine phosphate concentration (HP:0012599) | 2.22415384 |
77 | Vacuolated lymphocytes (HP:0001922) | 2.22365313 |
78 | Flat acetabular roof (HP:0003180) | 2.19172085 |
79 | Abnormal foot bone ossification (HP:0010675) | 2.16667153 |
80 | Abnormal hand bone ossification (HP:0010660) | 2.15678911 |
81 | Metaphyseal cupping (HP:0003021) | 2.15176323 |
82 | Neonatal short-limb short stature (HP:0008921) | 2.13447063 |
83 | Acanthocytosis (HP:0001927) | 2.13442254 |
84 | Xanthomatosis (HP:0000991) | 2.11643405 |
85 | Hypophosphatemia (HP:0002148) | 2.10728606 |
86 | Hemangiomatosis (HP:0007461) | 2.08440723 |
87 | Conjugated hyperbilirubinemia (HP:0002908) | 2.02910130 |
88 | Abnormal biliary tract morphology (HP:0012440) | 2.01707101 |
89 | Hyperphosphatemia (HP:0002905) | 2.01242140 |
90 | Vascular calcification (HP:0004934) | 2.01049447 |
91 | Megaloblastic anemia (HP:0001889) | 2.00791030 |
92 | Bicornuate uterus (HP:0000813) | 2.00446362 |
93 | Chondrocalcinosis (HP:0000934) | 1.99943533 |
94 | Pigmentary retinal degeneration (HP:0001146) | 1.99092639 |
95 | Ketosis (HP:0001946) | 1.93524154 |
96 | Abdominal distention (HP:0003270) | 1.92832438 |
97 | Rectal prolapse (HP:0002035) | 1.92020639 |
98 | * Decreased circulating renin level (HP:0003351) | 1.90752150 |
99 | Vomiting (HP:0002013) | 1.90366872 |
100 | Abnormality of the costochondral junction (HP:0000919) | 1.89710554 |
101 | Aortic dissection (HP:0002647) | 1.88984650 |
102 | Syncope (HP:0001279) | 1.88631843 |
103 | Rickets (HP:0002748) | 1.86563367 |
104 | Symptomatic seizures (HP:0011145) | 1.86063064 |
105 | Cardiovascular calcification (HP:0011915) | 1.86028627 |
106 | Enlarged epiphyses (HP:0010580) | 1.86022997 |
107 | Abnormality of complement system (HP:0005339) | 1.85950713 |
108 | Abnormality of the 1st metacarpal (HP:0010009) | 1.85297691 |
109 | Glomerulonephritis (HP:0000099) | 1.83888167 |
110 | Right ventricular cardiomyopathy (HP:0011663) | 1.83624038 |
111 | Glomerulosclerosis (HP:0000096) | 1.83055211 |
112 | Hyperammonemia (HP:0001987) | 1.82866737 |
113 | Abnormality of Sharpey fibers (HP:0100685) | 1.82578207 |
114 | Flat capital femoral epiphysis (HP:0003370) | 1.80400820 |
115 | Neonatal onset (HP:0003623) | 1.80182376 |
116 | Aortic aneurysm (HP:0004942) | 1.79729872 |
117 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.78917646 |
118 | Lymphangioma (HP:0100764) | 1.77457865 |
119 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.77216287 |
120 | Ureteral stenosis (HP:0000071) | 1.74843724 |
121 | Hyperparathyroidism (HP:0000843) | 1.73855763 |
122 | Abnormal cartilage morphology (HP:0002763) | 1.73510377 |
123 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.72787928 |
124 | Potter facies (HP:0002009) | 1.72578723 |
125 | Facial shape deformation (HP:0011334) | 1.72578723 |
126 | Enlarged kidneys (HP:0000105) | 1.71629328 |
127 | Visceral angiomatosis (HP:0100761) | 1.71205058 |
128 | Petechiae (HP:0000967) | 1.70752724 |
129 | Tubulointerstitial fibrosis (HP:0005576) | 1.68721125 |
130 | Arterial tortuosity (HP:0005116) | 1.65516959 |
131 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.63460488 |
132 | Short phalanx of the thumb (HP:0009660) | 1.63284226 |
133 | Abnormal pancreas size (HP:0012094) | 1.61577000 |
134 | Nausea (HP:0002018) | 1.61122134 |
135 | Wide cranial sutures (HP:0010537) | 1.60835285 |
136 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.58150092 |
137 | Spastic diplegia (HP:0001264) | 1.57714763 |
Rank | Gene Set | Z-score |
---|---|---|
1 | WNK4 | 7.20684516 |
2 | WNK3 | 6.16473919 |
3 | ACVR1B | 5.54918894 |
4 | OXSR1 | 5.49425647 |
5 | EPHA2 | 4.99282995 |
6 | STK39 | 3.14168202 |
7 | MST1R | 2.89479614 |
8 | STK38L | 2.46122728 |
9 | EPHB2 | 2.44102288 |
10 | BCKDK | 2.31664607 |
11 | MST4 | 2.24916476 |
12 | MYLK | 2.20455893 |
13 | MAP3K7 | 2.11227189 |
14 | PASK | 1.99293541 |
15 | PAK4 | 1.94069011 |
16 | MAP2K2 | 1.85647532 |
17 | FRK | 1.78616687 |
18 | NEK1 | 1.65817501 |
19 | LMTK2 | 1.61211799 |
20 | PTK6 | 1.51534126 |
21 | ERN1 | 1.46592561 |
22 | TESK1 | 1.43614530 |
23 | TRIB3 | 1.41524520 |
24 | STK24 | 1.36004117 |
25 | LRRK2 | 1.34701454 |
26 | MAP3K10 | 1.33232879 |
27 | SMG1 | 1.32129328 |
28 | PRPF4B | 1.26871678 |
29 | TNIK | 1.23577537 |
30 | TGFBR2 | 1.20919577 |
31 | WNK1 | 1.12878887 |
32 | SGK494 | 1.06160844 |
33 | SGK223 | 1.06160844 |
34 | MET | 1.04750356 |
35 | LATS1 | 1.04570796 |
36 | TESK2 | 1.02477544 |
37 | PDK3 | 1.00884686 |
38 | PDK4 | 1.00884686 |
39 | PTK2 | 0.96063623 |
40 | MATK | 0.92385900 |
41 | STK38 | 0.92045282 |
42 | PIK3CA | 0.88575226 |
43 | TTN | 0.88243502 |
44 | NME1 | 0.87231040 |
45 | DMPK | 0.86789175 |
46 | RIPK1 | 0.86684342 |
47 | PKN2 | 0.86681886 |
48 | PRKCI | 0.86480196 |
49 | PDK2 | 0.85503401 |
50 | PRKG2 | 0.85449015 |
51 | ERBB2 | 0.85156797 |
52 | EPHA3 | 0.84108718 |
53 | CDC42BPA | 0.83036468 |
54 | MAP3K12 | 0.82952366 |
55 | CAMKK1 | 0.81957013 |
56 | STK10 | 0.76008105 |
57 | MAP3K1 | 0.74244783 |
58 | GRK6 | 0.73678630 |
59 | AKT3 | 0.70797478 |
60 | KSR2 | 0.70293042 |
61 | FER | 0.69150020 |
62 | KSR1 | 0.68402857 |
63 | DYRK1B | 0.67769462 |
64 | NUAK1 | 0.66947898 |
65 | MAP3K2 | 0.66240295 |
66 | MAP3K8 | 0.64564887 |
67 | MAP2K1 | 0.63693908 |
68 | PDGFRA | 0.63140197 |
69 | EPHB1 | 0.62415401 |
70 | FGFR4 | 0.61315364 |
71 | LIMK1 | 0.60695612 |
72 | PRKAA2 | 0.59472488 |
73 | NLK | 0.58775574 |
74 | FGFR3 | 0.58127708 |
75 | PAK2 | 0.57725822 |
76 | DDR2 | 0.57619340 |
77 | TIE1 | 0.55099899 |
78 | PAK1 | 0.54254491 |
79 | TYK2 | 0.53964383 |
80 | SIK1 | 0.53162316 |
81 | CAMK2D | 0.51477795 |
82 | TAOK1 | 0.49422591 |
83 | RPS6KA2 | 0.49139942 |
84 | ROCK1 | 0.48945676 |
85 | GSK3A | 0.47968492 |
86 | ICK | 0.47950178 |
87 | PRKACG | 0.47450383 |
88 | ROCK2 | 0.46867324 |
89 | PRKAA1 | 0.44303279 |
90 | PAK3 | 0.43305729 |
91 | RIPK4 | 0.42776407 |
92 | EPHA4 | 0.41877771 |
93 | KDR | 0.41223605 |
94 | CAMK1D | 0.41001050 |
95 | SCYL2 | 0.40536511 |
96 | PDK1 | 0.39790651 |
97 | SGK3 | 0.39752703 |
98 | PDPK1 | 0.39194134 |
99 | MAP3K3 | 0.38045491 |
100 | AKT2 | 0.37684653 |
101 | ILK | 0.36448771 |
102 | PIK3CG | 0.36411477 |
103 | PRKCA | 0.36102064 |
104 | MAPKAPK3 | 0.35887435 |
105 | TTK | 0.35579509 |
106 | MAP3K11 | 0.35291390 |
107 | MAP4K1 | 0.34623846 |
108 | CSNK1A1 | 0.33568911 |
109 | STK11 | 0.30950239 |
110 | PRKCZ | 0.30196445 |
111 | SRC | 0.30182466 |
112 | ABL2 | 0.29717626 |
113 | EEF2K | 0.29008222 |
114 | MAPK11 | 0.28256211 |
115 | RET | 0.27739702 |
116 | FGFR1 | 0.26590399 |
117 | NEK9 | 0.25980638 |
118 | CDK19 | 0.24875920 |
119 | RPS6KC1 | 0.24695177 |
120 | RPS6KL1 | 0.24695177 |
121 | YES1 | 0.24460833 |
122 | DAPK3 | 0.24002920 |
123 | SGK2 | 0.22995148 |
124 | CAMK1G | 0.22875133 |
125 | MAP2K6 | 0.22202651 |
126 | MAPKAPK2 | 0.22175280 |
127 | PRKCD | 0.20605506 |
128 | MTOR | 0.20591161 |
129 | ARAF | 0.20072459 |
130 | AURKB | 0.19325960 |
131 | PTK2B | 0.18037079 |
132 | RPS6KA1 | 0.17961573 |
133 | BMX | 0.17312128 |
134 | SGK1 | 0.17115598 |
135 | FYN | 0.16742263 |
136 | RPS6KA6 | 0.13493854 |
137 | GRK1 | 0.11931921 |
138 | NEK6 | 0.11866837 |
139 | CDK6 | 0.10528106 |
140 | CASK | 0.10068163 |
141 | TBK1 | 0.09297882 |
142 | BRAF | 0.07708819 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 4.21912706 |
2 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.98840810 |
3 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.54999906 |
4 | Butanoate metabolism_Homo sapiens_hsa00650 | 3.36266953 |
5 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 3.33778431 |
6 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 3.26827442 |
7 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.86448117 |
8 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.84005905 |
9 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.72899116 |
10 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.54542558 |
11 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.45501526 |
12 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.39794678 |
13 | Mineral absorption_Homo sapiens_hsa04978 | 2.38947877 |
14 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.08267810 |
15 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.04178444 |
16 | Bile secretion_Homo sapiens_hsa04976 | 2.02964967 |
17 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.02538306 |
18 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.96916248 |
19 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.83696382 |
20 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.79944952 |
21 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.79275875 |
22 | Carbon metabolism_Homo sapiens_hsa01200 | 1.78177294 |
23 | Peroxisome_Homo sapiens_hsa04146 | 1.56790641 |
24 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.52571244 |
25 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.51443440 |
26 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.41708689 |
27 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.30047007 |
28 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.29323052 |
29 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.29012471 |
30 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.26020198 |
31 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.25291158 |
32 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.23160546 |
33 | Histidine metabolism_Homo sapiens_hsa00340 | 1.22317259 |
34 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.19475277 |
35 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.18422290 |
36 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.16664844 |
37 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.14796146 |
38 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.11103362 |
39 | Other glycan degradation_Homo sapiens_hsa00511 | 1.10343202 |
40 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.08684024 |
41 | * Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.99046834 |
42 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.98979395 |
43 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.95374802 |
44 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.95140796 |
45 | Lysine degradation_Homo sapiens_hsa00310 | 0.94754062 |
46 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.90708686 |
47 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.89484076 |
48 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.88266402 |
49 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.83450470 |
50 | Parkinsons disease_Homo sapiens_hsa05012 | 0.79888989 |
51 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.79136717 |
52 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.76474691 |
53 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.75779474 |
54 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.74858804 |
55 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.74722035 |
56 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.73833373 |
57 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.72897126 |
58 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.70829487 |
59 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.70713628 |
60 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.68811171 |
61 | Tight junction_Homo sapiens_hsa04530 | 0.68556098 |
62 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.65721767 |
63 | Retinol metabolism_Homo sapiens_hsa00830 | 0.64624579 |
64 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.61690925 |
65 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.60772170 |
66 | Asthma_Homo sapiens_hsa05310 | 0.57488788 |
67 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.56386223 |
68 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.56305709 |
69 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.55245613 |
70 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.52815794 |
71 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.52640713 |
72 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.51702715 |
73 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.50433111 |
74 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.50243814 |
75 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.49303247 |
76 | Alzheimers disease_Homo sapiens_hsa05010 | 0.49274049 |
77 | Metabolic pathways_Homo sapiens_hsa01100 | 0.48180852 |
78 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.46327111 |
79 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.45133411 |
80 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.44848553 |
81 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.43250249 |
82 | Lysosome_Homo sapiens_hsa04142 | 0.41025337 |
83 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.40548121 |
84 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.40445101 |
85 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.40001931 |
86 | Hepatitis C_Homo sapiens_hsa05160 | 0.37539284 |
87 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.37400270 |
88 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.37382588 |
89 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.36802400 |
90 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.36557363 |
91 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.36391334 |
92 | Sulfur relay system_Homo sapiens_hsa04122 | 0.36212075 |
93 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.35358636 |
94 | Galactose metabolism_Homo sapiens_hsa00052 | 0.34781752 |
95 | Bladder cancer_Homo sapiens_hsa05219 | 0.33008844 |
96 | Renin secretion_Homo sapiens_hsa04924 | 0.32762579 |
97 | Huntingtons disease_Homo sapiens_hsa05016 | 0.29432189 |
98 | * Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.28154065 |
99 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.27788446 |
100 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.25808483 |
101 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.24925219 |
102 | Adherens junction_Homo sapiens_hsa04520 | 0.24834247 |
103 | Allograft rejection_Homo sapiens_hsa05330 | 0.24509717 |
104 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.24198458 |
105 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.23938850 |
106 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.20276320 |
107 | Thyroid cancer_Homo sapiens_hsa05216 | 0.17760853 |
108 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.17699207 |
109 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.17136888 |
110 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.16703028 |
111 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.15733045 |
112 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.13776276 |
113 | Focal adhesion_Homo sapiens_hsa04510 | 0.12715725 |
114 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.12058349 |
115 | Insulin resistance_Homo sapiens_hsa04931 | 0.11975453 |
116 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.11894389 |
117 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.11397231 |
118 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.11389943 |
119 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.11177136 |
120 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.07517742 |
121 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.06470906 |
122 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.05514947 |
123 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.04779287 |
124 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.02910617 |
125 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.01844490 |
126 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.01306377 |