HSD17B13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1exogenous drug catabolic process (GO:0042738)9.58391176
2L-phenylalanine catabolic process (GO:0006559)7.50370233
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.50370233
4epoxygenase P450 pathway (GO:0019373)7.50076964
5omega-hydroxylase P450 pathway (GO:0097267)7.30886159
6L-phenylalanine metabolic process (GO:0006558)7.18439786
7erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.18439786
8aromatic amino acid family catabolic process (GO:0009074)6.71675221
9triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.46532305
10oxidative demethylation (GO:0070989)6.28431147
11indole-containing compound catabolic process (GO:0042436)6.03203531
12indolalkylamine catabolic process (GO:0046218)6.03203531
13tryptophan catabolic process (GO:0006569)6.03203531
14drug metabolic process (GO:0017144)5.94175481
15kynurenine metabolic process (GO:0070189)5.92172655
16ethanol metabolic process (GO:0006067)5.85154845
17bile acid biosynthetic process (GO:0006699)5.85127995
18glyoxylate metabolic process (GO:0046487)5.69494024
19tryptophan metabolic process (GO:0006568)5.68266817
20high-density lipoprotein particle remodeling (GO:0034375)5.62332173
21alpha-linolenic acid metabolic process (GO:0036109)5.60033454
22urea metabolic process (GO:0019627)5.57866304
23urea cycle (GO:0000050)5.57866304
24negative regulation of fibrinolysis (GO:0051918)5.57777020
25cysteine metabolic process (GO:0006534)5.46398230
26sulfur amino acid catabolic process (GO:0000098)5.39052192
27regulation of fibrinolysis (GO:0051917)5.35393331
28protein carboxylation (GO:0018214)5.30571288
29peptidyl-glutamic acid carboxylation (GO:0017187)5.30571288
30regulation of protein activation cascade (GO:2000257)5.21605724
31complement activation, alternative pathway (GO:0006957)5.19989175
32phenylpropanoid metabolic process (GO:0009698)5.16283748
33nitrogen cycle metabolic process (GO:0071941)5.13729099
34serine family amino acid catabolic process (GO:0009071)5.07826617
35bile acid metabolic process (GO:0008206)5.04878820
36S-adenosylmethionine metabolic process (GO:0046500)4.98248884
37regulation of cholesterol esterification (GO:0010872)4.96704680
38reverse cholesterol transport (GO:0043691)4.94774840
39regulation of triglyceride catabolic process (GO:0010896)4.89685828
40aromatic amino acid family metabolic process (GO:0009072)4.88995532
41regulation of complement activation (GO:0030449)4.86066243
42protein-lipid complex remodeling (GO:0034368)4.82807532
43macromolecular complex remodeling (GO:0034367)4.82807532
44plasma lipoprotein particle remodeling (GO:0034369)4.82807532
45fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.81533654
46homocysteine metabolic process (GO:0050667)4.80289335
47alkaloid metabolic process (GO:0009820)4.77245382
48phospholipid efflux (GO:0033700)4.73147770
49negative regulation of sterol transport (GO:0032372)4.68935215
50negative regulation of cholesterol transport (GO:0032375)4.68935215
51tyrosine metabolic process (GO:0006570)4.67030289
52triglyceride homeostasis (GO:0070328)4.63153033
53acylglycerol homeostasis (GO:0055090)4.63153033
54cellular ketone body metabolic process (GO:0046950)4.62469354
55alpha-amino acid catabolic process (GO:1901606)4.62188743
56amino-acid betaine metabolic process (GO:0006577)4.55322322
57lysine catabolic process (GO:0006554)4.53900276
58lysine metabolic process (GO:0006553)4.53900276
59bile acid and bile salt transport (GO:0015721)4.46766842
60glycine metabolic process (GO:0006544)4.42978099
61coenzyme catabolic process (GO:0009109)4.40082954
62plasma lipoprotein particle clearance (GO:0034381)4.40073400
63cellular glucuronidation (GO:0052695)4.33402611
64cellular amino acid catabolic process (GO:0009063)4.28556576
65indolalkylamine metabolic process (GO:0006586)4.27961431
66cholesterol efflux (GO:0033344)4.25769838
67imidazole-containing compound metabolic process (GO:0052803)4.24363669
68serine family amino acid metabolic process (GO:0009069)4.22869292
69amine catabolic process (GO:0009310)4.19091499
70cellular biogenic amine catabolic process (GO:0042402)4.19091499
71glutamate metabolic process (GO:0006536)4.18104608
72cellular modified amino acid catabolic process (GO:0042219)4.12833975
73serine family amino acid biosynthetic process (GO:0009070)4.11042953
74benzene-containing compound metabolic process (GO:0042537)4.07112237
75intestinal cholesterol absorption (GO:0030299)4.03676731
76plasma lipoprotein particle assembly (GO:0034377)4.02816836
77ethanol oxidation (GO:0006069)4.02605283
78ketone body metabolic process (GO:1902224)4.00481271
79low-density lipoprotein particle remodeling (GO:0034374)3.98383680
80arginine metabolic process (GO:0006525)3.94664601
81fibrinolysis (GO:0042730)3.93129760
82positive regulation of lipoprotein lipase activity (GO:0051006)3.93011779
83positive regulation of triglyceride lipase activity (GO:0061365)3.93011779
84primary alcohol catabolic process (GO:0034310)3.91411430
85aldehyde catabolic process (GO:0046185)3.90295611
86dicarboxylic acid biosynthetic process (GO:0043650)3.88736338
87negative regulation of blood coagulation (GO:0030195)3.87351255
88negative regulation of hemostasis (GO:1900047)3.87351255
89drug catabolic process (GO:0042737)3.86849244
90uronic acid metabolic process (GO:0006063)3.83981012
91glucuronate metabolic process (GO:0019585)3.83981012
92blood coagulation, intrinsic pathway (GO:0007597)3.80056800
93heme transport (GO:0015886)3.78193430
94cofactor catabolic process (GO:0051187)3.77550836
95positive regulation of lipid catabolic process (GO:0050996)3.77302317
96organic acid catabolic process (GO:0016054)3.75762951
97carboxylic acid catabolic process (GO:0046395)3.75762951
98cholesterol homeostasis (GO:0042632)3.75605273
99phospholipid homeostasis (GO:0055091)3.75530965
100amino acid salvage (GO:0043102)3.75508110
101L-methionine salvage (GO:0071267)3.75508110
102L-methionine biosynthetic process (GO:0071265)3.75508110
103very-low-density lipoprotein particle assembly (GO:0034379)3.74731676
104negative regulation of lipase activity (GO:0060192)3.74696174
105short-chain fatty acid metabolic process (GO:0046459)3.70431236
106xenobiotic metabolic process (GO:0006805)3.70418902
107sterol homeostasis (GO:0055092)3.69344304
108complement activation, classical pathway (GO:0006958)3.69102374
109regulation of plasminogen activation (GO:0010755)3.66790675
110plasma lipoprotein particle organization (GO:0071827)3.65696860
111protein activation cascade (GO:0072376)3.65067309
112complement activation (GO:0006956)3.65018907
113regulation of bile acid biosynthetic process (GO:0070857)3.63868108
114cytolysis (GO:0019835)3.61117273
115protein-lipid complex assembly (GO:0065005)3.60884748
116negative regulation of protein activation cascade (GO:2000258)3.59435992
117flavonoid metabolic process (GO:0009812)3.57957977
118fat-soluble vitamin biosynthetic process (GO:0042362)3.55345810
119response to nitrosative stress (GO:0051409)3.55012640
120regulation of cholesterol homeostasis (GO:2000188)3.54923693
121steroid catabolic process (GO:0006706)3.53420873
122primary alcohol metabolic process (GO:0034308)3.53170302
123negative regulation of coagulation (GO:0050819)3.51599172
124negative regulation of wound healing (GO:0061045)3.44204444
125regulation of humoral immune response (GO:0002920)3.41339042
126sodium-independent organic anion transport (GO:0043252)3.34006599
127vitamin biosynthetic process (GO:0009110)3.26086314
128acute-phase response (GO:0006953)3.23724673
129hormone catabolic process (GO:0042447)3.23499684
130disruption of cells of other organism involved in symbiotic interaction (GO:0051818)3.19865067
131killing of cells in other organism involved in symbiotic interaction (GO:0051883)3.19865067
132arginine catabolic process (GO:0006527)3.19769800
133negative regulation of complement activation (GO:0045916)3.19077189

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RXR_22158963_ChIP-Seq_LIVER_Mouse8.34383851
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.16152651
3* EGR1_23403033_ChIP-Seq_LIVER_Mouse6.95137712
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.43217146
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.29448056
6* CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.07442955
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.84468167
8CEBPB_23403033_ChIP-Seq_LIVER_Mouse4.00879814
9NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.98398848
10ZNF274_21170338_ChIP-Seq_K562_Hela2.68731579
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.64538919
12VDR_22108803_ChIP-Seq_LS180_Human2.35364627
13GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.12482462
14HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.05307974
15TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.03643892
16ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.8961153
17TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.99553211
18GBX2_23144817_ChIP-Seq_PC3_Human1.94583776
19POU3F2_20337985_ChIP-ChIP_501MEL_Human1.91253422
20IGF1R_20145208_ChIP-Seq_DFB_Human1.90656484
21ER_23166858_ChIP-Seq_MCF-7_Human1.80755414
22ZFP57_27257070_Chip-Seq_ESCs_Mouse1.68395004
23TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.65163077
24FLI1_27457419_Chip-Seq_LIVER_Mouse1.61876803
25HTT_18923047_ChIP-ChIP_STHdh_Human1.61241557
26PIAS1_25552417_ChIP-Seq_VCAP_Human1.60475354
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.59619133
28FOXA2_19822575_ChIP-Seq_HepG2_Human1.59511657
29IRF1_19129219_ChIP-ChIP_H3396_Human1.57226505
30NFE2_27457419_Chip-Seq_LIVER_Mouse1.49607584
31CLOCK_20551151_ChIP-Seq_293T_Human1.45285403
32FOXA1_27270436_Chip-Seq_PROSTATE_Human1.40614456
33FOXA1_25329375_ChIP-Seq_VCAP_Human1.40614456
34* HNF4A_19822575_ChIP-Seq_HepG2_Human1.40406585
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.39761755
36EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.38689931
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.36556242
38GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.35541716
39SUZ12_27294783_Chip-Seq_NPCs_Mouse1.35134163
40GATA1_22025678_ChIP-Seq_K562_Human1.34437361
41PCGF2_27294783_Chip-Seq_NPCs_Mouse1.32979258
42EZH2_27294783_Chip-Seq_NPCs_Mouse1.32319228
43ETV2_25802403_ChIP-Seq_MESCs_Mouse1.31971836
44P300_19829295_ChIP-Seq_ESCs_Human1.31572012
45TCF4_22108803_ChIP-Seq_LS180_Human1.29667615
46STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.28639318
47FOXA1_21572438_ChIP-Seq_LNCaP_Human1.25958608
48* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.25767275
49* SOX2_19829295_ChIP-Seq_ESCs_Human1.25068186
50* NANOG_19829295_ChIP-Seq_ESCs_Human1.25068186
51THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.22015110
52GATA3_21878914_ChIP-Seq_MCF-7_Human1.21825836
53CBP_20019798_ChIP-Seq_JUKART_Human1.20264525
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.20264525
55* RXRA_24833708_ChIP-Seq_LIVER_Mouse1.20191400
56STAT3_23295773_ChIP-Seq_U87_Human1.20101276
57UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.17433479
58MYC_19829295_ChIP-Seq_ESCs_Human1.16312336
59STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.15282751
60TCF4_23295773_ChIP-Seq_U87_Human1.15199442
61PHF8_20622853_ChIP-Seq_HELA_Human1.14072435
62CRX_20693478_ChIP-Seq_RETINA_Mouse1.13998438
63AR_25329375_ChIP-Seq_VCAP_Human1.13917886
64EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.13423375
65CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.07550410
66FUS_26573619_Chip-Seq_HEK293_Human1.07494844
67NR3C1_21868756_ChIP-Seq_MCF10A_Human1.06954760
68* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.06950534
69ETV1_20927104_ChIP-Seq_GIST48_Human1.06832392
70FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.06091277
71SMAD4_21799915_ChIP-Seq_A2780_Human1.05292385
72MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.05196406
73HNFA_21074721_ChIP-Seq_CACO-2_Human1.05172106
74SMAD4_21741376_ChIP-Seq_EPCs_Human1.05096066
75TP53_22573176_ChIP-Seq_HFKS_Human1.04091231
76SOX2_27498859_Chip-Seq_STOMACH_Mouse1.03306371
77IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.02782044
78ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.02308850
79SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.01987087
80SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.01615836
81* CDX2_22108803_ChIP-Seq_LS180_Human1.00337531
82ESR1_15608294_ChIP-ChIP_MCF-7_Human0.99748196
83RUNX2_22187159_ChIP-Seq_PCA_Human0.98853149
84EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.98482939
85GATA6_21074721_ChIP-Seq_CACO-2_Human0.98152644
86ERA_21632823_ChIP-Seq_H3396_Human0.97120868
87PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.96599850
88NANOG_20526341_ChIP-Seq_ESCs_Human0.96274344
89STAT3_18555785_Chip-Seq_ESCs_Mouse0.96181663
90PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.96178366
91NFYA_21822215_ChIP-Seq_K562_Human0.95809267
92IRF8_22096565_ChIP-ChIP_GC-B_Human0.95013458
93GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.94468060
94P53_22387025_ChIP-Seq_ESCs_Mouse0.94049570
95OCT4_21477851_ChIP-Seq_ESCs_Mouse0.93525560
96CBX2_22325352_ChIP-Seq_293T-Rex_Human0.93498830
97GATA4_25053715_ChIP-Seq_YYC3_Human0.93369429
98TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.92943051
99RBPJ_21746931_ChIP-Seq_IB4_Human0.92487800
100PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.91856525
101ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.87056971
102KAP1_22055183_ChIP-Seq_ESCs_Mouse0.83989462
103RARG_19884340_ChIP-ChIP_MEFs_Mouse0.83299392
104AUTS2_25519132_ChIP-Seq_293T-REX_Human0.82359687
105ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.80326911
106SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.78380175
107RARA_24833708_ChIP-Seq_LIVER_Mouse0.76502334
108SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.76449685
109Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.71643530
110BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.70695705
111BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.69962623
112CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.69927122
113ESR2_21235772_ChIP-Seq_MCF-7_Human0.67808115
114* AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.67673946
115NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.65815258
116RAD21_21589869_ChIP-Seq_MESCs_Mouse0.65460401
117NRF2_20460467_ChIP-Seq_MEFs_Mouse0.63930242
118NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.63930242
119NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.63333699
120SALL4_18804426_ChIP-ChIP_XEN_Mouse0.62949653
121RARB_24833708_ChIP-Seq_LIVER_Mouse0.62692843
122NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.60620453
123RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.58584581
124E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.58493189
125* CEBPB_22108803_ChIP-Seq_LS180_Human0.58241828
126ZNF263_19887448_ChIP-Seq_K562_Human0.57520986
127FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.55926736
128FOXA1_25552417_ChIP-Seq_VCAP_Human0.55892723
129EGR1_19032775_ChIP-ChIP_M12_Human0.55732376
130PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.55291271
131MYC_19915707_ChIP-ChIP_AK7_Human0.54930229
132CDX2_20551321_ChIP-Seq_CACO-2_Human0.54708956
133PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.52994828
134LXR_22292898_ChIP-Seq_THP-1_Human0.52901709
135* AR_20517297_ChIP-Seq_VCAP_Human0.52569192
136* ESET_19884257_ChIP-Seq_ESCs_Mouse0.52012988
137STAT1_17558387_ChIP-Seq_HELA_Human0.50971130
138ERG_21242973_ChIP-ChIP_JURKAT_Human0.50918927
139* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.50034954
140STAT3_1855785_ChIP-Seq_MESCs_Mouse0.49731514
141CBP_21632823_ChIP-Seq_H3396_Human0.49046270
142GATA6_25053715_ChIP-Seq_YYC3_Human0.48714474
143* P53_21459846_ChIP-Seq_SAOS-2_Human0.48125224
144FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.47991631
145PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.47954570
146TAF2_19829295_ChIP-Seq_ESCs_Human0.47855739
147ESR1_21235772_ChIP-Seq_MCF-7_Human0.47620771
148TAF15_26573619_Chip-Seq_HEK293_Human0.45153170
149SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.44731691
150FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.42796017
151GATA1_19941827_ChIP-Seq_MEL_Mouse0.41576531
152PPAR_26484153_Chip-Seq_NCI-H1993_Human0.41492416
153STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.41302365
154* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.41086258
155FOXO3_23340844_ChIP-Seq_DLD1_Human0.40016486
156BCAT_22108803_ChIP-Seq_LS180_Human0.39855865
157GATA2_19941826_ChIP-Seq_K562_Human0.39030370
158CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.38991496
159SOX2_20726797_ChIP-Seq_SW620_Human0.38504910
160GATA1_19941826_ChIP-Seq_K562_Human0.37777270
161OCT4_20526341_ChIP-Seq_ESCs_Human0.37383628
162ESR1_20079471_ChIP-ChIP_T-47D_Human0.37365586
163MYC_27129775_Chip-Seq_CORNEA_Mouse0.36773256
164SPI1_26923725_Chip-Seq_HPCs_Mouse0.36506466
165FOXH1_21741376_ChIP-Seq_EPCs_Human0.36399367
166NCOR_22424771_ChIP-Seq_293T_Human0.35962505
167* CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.35946748
168SOX3_22085726_ChIP-Seq_MUSCLE_Mouse0.35691018
169LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.35565927

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.23655847
2MP0005360_urolithiasis7.37666860
3MP0005085_abnormal_gallbladder_physiolo6.46880752
4MP0005365_abnormal_bile_salt6.41000956
5MP0008875_abnormal_xenobiotic_pharmacok4.99191260
6MP0003806_abnormal_nucleotide_metabolis4.25519957
7MP0003252_abnormal_bile_duct3.85596918
8MP0010329_abnormal_lipoprotein_level3.54387118
9MP0005083_abnormal_biliary_tract3.50002753
10MP0009840_abnormal_foam_cell3.28460572
11MP0001666_abnormal_nutrient_absorption3.07763179
12MP0005332_abnormal_amino_acid2.71640260
13MP0003195_calcinosis2.67785853
14MP0003191_abnormal_cellular_cholesterol2.34486376
15MP0003868_abnormal_feces_composition2.15799303
16MP0000609_abnormal_liver_physiology2.12462428
17MP0002118_abnormal_lipid_homeostasis2.12028806
18MP0004019_abnormal_vitamin_homeostasis2.06708902
19MP0002138_abnormal_hepatobiliary_system1.94668710
20MP0005319_abnormal_enzyme/_coenzyme1.79118299
21MP0001764_abnormal_homeostasis1.68315583
22MP0009697_abnormal_copulation1.59069287
23MP0005451_abnormal_body_composition1.54790383
24MP0005584_abnormal_enzyme/coenzyme_acti1.51823417
25MP0005646_abnormal_pituitary_gland1.34904127
26MP0003011_delayed_dark_adaptation1.33449960
27MP0003186_abnormal_redox_activity1.27105972
28MP0009643_abnormal_urine_homeostasis1.23904080
29MP0003656_abnormal_erythrocyte_physiolo1.22716551
30MP0005551_abnormal_eye_electrophysiolog1.19135462
31MP0000598_abnormal_liver_morphology1.15637205
32MP0003705_abnormal_hypodermis_morpholog1.13517242
33MP0005647_abnormal_sex_gland1.12967331
34MP0001986_abnormal_taste_sensitivity1.08386209
35MP0005187_abnormal_penis_morphology1.07525058
36MP0004043_abnormal_pH_regulation1.05814415
37MP0000604_amyloidosis1.04538697
38MP0005220_abnormal_exocrine_pancreas1.04393901
39MP0005084_abnormal_gallbladder_morpholo1.03130731
40MP0009764_decreased_sensitivity_to1.01418614
41MP0009763_increased_sensitivity_to0.99287571
42MP0004142_abnormal_muscle_tone0.97255959
43MP0002254_reproductive_system_inflammat0.95651636
44MP0005636_abnormal_mineral_homeostasis0.92171542
45MP0002282_abnormal_trachea_morphology0.91546770
46MP0009745_abnormal_behavioral_response0.90498920
47MP0008469_abnormal_protein_level0.87958027
48MP0005408_hypopigmentation0.86699831
49MP0009642_abnormal_blood_homeostasis0.86264608
50MP0010368_abnormal_lymphatic_system0.86065168
51MP0006036_abnormal_mitochondrial_physio0.84675372
52MP0002876_abnormal_thyroid_physiology0.81217077
53MP0002078_abnormal_glucose_homeostasis0.79798388
54MP0009765_abnormal_xenobiotic_induced0.79780212
55MP0001984_abnormal_olfaction0.79098827
56MP0002102_abnormal_ear_morphology0.78218378
57MP0005376_homeostasis/metabolism_phenot0.78046802
58MP0009046_muscle_twitch0.73581753
59MP0004885_abnormal_endolymph0.72950265
60MP0004133_heterotaxia0.72815036
61MP0005645_abnormal_hypothalamus_physiol0.71085410
62MP0005670_abnormal_white_adipose0.70915644
63MP0001968_abnormal_touch/_nociception0.70665030
64MP0005334_abnormal_fat_pad0.68897203
65MP0001501_abnormal_sleep_pattern0.67995282
66MP0002971_abnormal_brown_adipose0.67725908
67MP0005535_abnormal_body_temperature0.67341102
68MP0002638_abnormal_pupillary_reflex0.66442525
69MP0004130_abnormal_muscle_cell0.66020199
70MP0002653_abnormal_ependyma_morphology0.64823729
71MP0005448_abnormal_energy_balance0.64495461
72MP0004147_increased_porphyrin_level0.63855904
73MP0005266_abnormal_metabolism0.63814721
74MP0002909_abnormal_adrenal_gland0.63695973
75MP0001661_extended_life_span0.63461332
76MP0003690_abnormal_glial_cell0.63292923
77MP0003646_muscle_fatigue0.61814148
78MP0002277_abnormal_respiratory_mucosa0.60116339
79MP0009053_abnormal_anal_canal0.59508714
80MP0003329_amyloid_beta_deposits0.58900253
81MP0002822_catalepsy0.58774565
82MP0000639_abnormal_adrenal_gland0.58334050
83MP0002272_abnormal_nervous_system0.57596295
84MP0006035_abnormal_mitochondrial_morpho0.57312661
85MP0001756_abnormal_urination0.56115437
86MP0005253_abnormal_eye_physiology0.55495028
87MP0003879_abnormal_hair_cell0.54574675
88MP0003638_abnormal_response/metabolism_0.51429202
89MP0001502_abnormal_circadian_rhythm0.51427220
90MP0002736_abnormal_nociception_after0.51058538
91MP0008877_abnormal_DNA_methylation0.50970168
92MP0005464_abnormal_platelet_physiology0.49277870
93MP0006276_abnormal_autonomic_nervous0.48964327
94MP0001485_abnormal_pinna_reflex0.48600231
95MP0000372_irregular_coat_pigmentation0.48320172
96MP0003136_yellow_coat_color0.47944428
97MP0003718_maternal_effect0.47641920
98MP0005167_abnormal_blood-brain_barrier0.47024873
99MP0006072_abnormal_retinal_apoptosis0.46983130
100MP0005395_other_phenotype0.46980791
101MP0001486_abnormal_startle_reflex0.45967005
102MP0002064_seizures0.45366940
103MP0004782_abnormal_surfactant_physiolog0.45353481
104MP0002928_abnormal_bile_duct0.45249938
105MP0009785_altered_susceptibility_to0.44686786
106MP0010386_abnormal_urinary_bladder0.44349050
107MP0003953_abnormal_hormone_level0.43930605
108MP0006292_abnormal_olfactory_placode0.43897664
109MP0001905_abnormal_dopamine_level0.43104740
110MP0008873_increased_physiological_sensi0.42537718
111MP0002136_abnormal_kidney_physiology0.42470674
112MP0008874_decreased_physiological_sensi0.40895009
113MP0003436_decreased_susceptibility_to0.38893128
114MP0008872_abnormal_physiological_respon0.38807298
115MP0003075_altered_response_to0.38316617
116MP0003724_increased_susceptibility_to0.36973274
117MP0005166_decreased_susceptibility_to0.36545240
118MP0002796_impaired_skin_barrier0.35770636
119MP0005248_abnormal_Harderian_gland0.35496992
120MP0000579_abnormal_nail_morphology0.33863179
121MP0005666_abnormal_adipose_tissue0.33782788
122MP0004381_abnormal_hair_follicle0.33712957
123MP0002837_dystrophic_cardiac_calcinosis0.33352500
124MP0004264_abnormal_extraembryonic_tissu0.32471990
125MP0009672_abnormal_birth_weight0.32429613
126MP0001243_abnormal_dermal_layer0.31436265
127MP0001845_abnormal_inflammatory_respons0.31123640
128MP0006082_CNS_inflammation0.30921258
129MP0009115_abnormal_fat_cell0.29258030
130MP0009384_cardiac_valve_regurgitation0.29240600
131MP0000230_abnormal_systemic_arterial0.29237000
132MP0002970_abnormal_white_adipose0.29117117
133MP0000249_abnormal_blood_vessel0.28097859
134MP0003959_abnormal_lean_body0.28025942
135MP0004883_abnormal_blood_vessel0.27758003
136MP0002168_other_aberrant_phenotype0.26992614
137MP0001944_abnormal_pancreas_morphology0.26434666
138MP0002132_abnormal_respiratory_system0.25696297
139MP0005058_abnormal_lysosome_morphology0.25616881
140MP0002060_abnormal_skin_morphology0.25103284

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.39120278
2Deep venous thrombosis (HP:0002625)7.38603298
3Intrahepatic cholestasis (HP:0001406)7.20569899
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.61637265
5Prolonged partial thromboplastin time (HP:0003645)6.50136221
6Hypobetalipoproteinemia (HP:0003563)6.46124427
7Xanthomatosis (HP:0000991)6.16968778
8Hyperlipoproteinemia (HP:0010980)5.56871023
9Complement deficiency (HP:0004431)5.24563100
10Hypolipoproteinemia (HP:0010981)4.83637154
11Joint hemorrhage (HP:0005261)4.72912749
12Hyperammonemia (HP:0001987)4.61489469
13Hyperglycinemia (HP:0002154)4.49372237
14Abnormality of the common coagulation pathway (HP:0010990)4.47741964
15Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.40955614
16Fat malabsorption (HP:0002630)4.38953016
17Epidermoid cyst (HP:0200040)4.34951213
18Ketosis (HP:0001946)4.29036124
19Abnormality of methionine metabolism (HP:0010901)4.28828894
20Abnormality of sulfur amino acid metabolism (HP:0004339)4.26440624
21Hypoalphalipoproteinemia (HP:0003233)4.22760770
22Abnormality of aspartate family amino acid metabolism (HP:0010899)4.13144549
23Abnormality of glutamine family amino acid metabolism (HP:0010902)4.04493191
24Hypoglycemic coma (HP:0001325)3.96418705
25Hyperglycinuria (HP:0003108)3.94459498
26Abnormality of serine family amino acid metabolism (HP:0010894)3.92468114
27Abnormality of glycine metabolism (HP:0010895)3.92468114
28Abnormality of the intrinsic pathway (HP:0010989)3.89607134
29Abnormality of complement system (HP:0005339)3.81643292
30Conjugated hyperbilirubinemia (HP:0002908)3.77450589
31Abnormality of pyrimidine metabolism (HP:0004353)3.74229516
32Hypercholesterolemia (HP:0003124)3.57424719
33Steatorrhea (HP:0002570)3.45516608
34Absent/shortened dynein arms (HP:0200106)3.43659063
35Dynein arm defect of respiratory motile cilia (HP:0012255)3.43659063
36Abnormality of fatty-acid metabolism (HP:0004359)3.40774762
37Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.40381604
38Abnormal respiratory motile cilium morphology (HP:0005938)3.37874131
39Abnormal respiratory epithelium morphology (HP:0012253)3.37874131
40Hyperbilirubinemia (HP:0002904)3.32841886
41Pancreatic cysts (HP:0001737)3.11443918
42Abnormality of serum amino acid levels (HP:0003112)3.09523078
43Abnormal biliary tract physiology (HP:0012439)3.06814373
44Bile duct proliferation (HP:0001408)3.06814373
45Abnormal ciliary motility (HP:0012262)3.05941827
46Ketoacidosis (HP:0001993)3.05914886
47Spontaneous abortion (HP:0005268)3.04939750
48Delayed CNS myelination (HP:0002188)3.04538394
49Abnormality of nucleobase metabolism (HP:0010932)3.03922908
50Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.96997731
51Hypochromic microcytic anemia (HP:0004840)2.90971826
52Hepatocellular carcinoma (HP:0001402)2.90401358
53Myocardial infarction (HP:0001658)2.90140392
54True hermaphroditism (HP:0010459)2.88495353
55Abnormal respiratory motile cilium physiology (HP:0012261)2.87930641
56Pancreatic fibrosis (HP:0100732)2.83096019
57Metabolic acidosis (HP:0001942)2.79289888
58Fair hair (HP:0002286)2.79220155
59Molar tooth sign on MRI (HP:0002419)2.71176551
60Abnormality of midbrain morphology (HP:0002418)2.71176551
61Abnormality of dicarboxylic acid metabolism (HP:0010995)2.70862819
62Dicarboxylic aciduria (HP:0003215)2.70862819
63Abnormality of purine metabolism (HP:0004352)2.68769604
64Lethargy (HP:0001254)2.67634429
65Systemic lupus erythematosus (HP:0002725)2.65944008
66Skin nodule (HP:0200036)2.65924218
67Chronic hepatic failure (HP:0100626)2.64931529
68Vascular calcification (HP:0004934)2.60890143
69Hypoglycemic seizures (HP:0002173)2.57358736
70Nephritis (HP:0000123)2.57286351
71Acanthocytosis (HP:0001927)2.54279859
72Gout (HP:0001997)2.53302675
73Cerebral edema (HP:0002181)2.52038279
74Rhinitis (HP:0012384)2.50836699
75Abnormal gallbladder morphology (HP:0012437)2.43414528
76Glomerulonephritis (HP:0000099)2.43127757
77Glycosuria (HP:0003076)2.42742173
78Abnormality of urine glucose concentration (HP:0011016)2.42742173
79Abnormal gallbladder physiology (HP:0012438)2.40321844
80Cholecystitis (HP:0001082)2.40321844
81Spastic diplegia (HP:0001264)2.38734938
82Cholelithiasis (HP:0001081)2.37986621
83Abnormality of the renal cortex (HP:0011035)2.37538512
84Arthropathy (HP:0003040)2.35263075
85Malnutrition (HP:0004395)2.33870782
86Mitral stenosis (HP:0001718)2.32547286
87Cardiovascular calcification (HP:0011915)2.31017361
88Irritability (HP:0000737)2.30139127
89Pancreatitis (HP:0001733)2.29144464
90Amyloidosis (HP:0011034)2.29095684
91Recurrent gram-negative bacterial infections (HP:0005420)2.27990677
92Neonatal onset (HP:0003623)2.25831602
93Nephronophthisis (HP:0000090)2.25151265
94Decreased central vision (HP:0007663)2.24863406
95Esophageal varix (HP:0002040)2.23182566
96Gingival bleeding (HP:0000225)2.19536165
97Menorrhagia (HP:0000132)2.19043205
98Hyperphosphaturia (HP:0003109)2.18717496
99Late onset (HP:0003584)2.18714106
100Brushfield spots (HP:0001088)2.15214437
101Sensorimotor neuropathy (HP:0007141)2.14202613
102Osteomalacia (HP:0002749)2.13845824
103Vomiting (HP:0002013)2.10678489
104Generalized hypopigmentation of hair (HP:0011358)2.10215752
105Generalized aminoaciduria (HP:0002909)2.09605707
106Cystic liver disease (HP:0006706)2.08995858
107Opisthotonus (HP:0002179)2.07687405
108Thrombophlebitis (HP:0004418)2.05559484
109Hyperinsulinemic hypoglycemia (HP:0000825)2.05098495
110Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.04122567
111Abnormality of alanine metabolism (HP:0010916)2.04122567
112Hyperalaninemia (HP:0003348)2.04122567
113Enlarged kidneys (HP:0000105)2.04072411
114Tubular atrophy (HP:0000092)2.03907746
115Hyperventilation (HP:0002883)2.00735507
116Poikilocytosis (HP:0004447)1.99608514
117Abnormality of the gallbladder (HP:0005264)1.98933590
118Abnormality of the renal medulla (HP:0100957)1.94759525
119Hemorrhage of the eye (HP:0011885)1.94109703
120Male pseudohermaphroditism (HP:0000037)1.93225049
121Rickets (HP:0002748)1.92419795
122Renal cortical cysts (HP:0000803)1.91438685
123Hypothermia (HP:0002045)1.91391222
124Reduced antithrombin III activity (HP:0001976)1.89688863
125Abnormal cartilage morphology (HP:0002763)1.88519501
126Abnormality of transition element cation homeostasis (HP:0011030)1.87235258
127Abnormality of iron homeostasis (HP:0011031)1.87010746
128Chronic bronchitis (HP:0004469)1.86554980
129Pulmonary embolism (HP:0002204)1.85866685
130Hypophosphatemic rickets (HP:0004912)1.81599593
131Elevated hepatic transaminases (HP:0002910)1.81282781
132Abnormality of vitamin metabolism (HP:0100508)1.80680767
133Alkalosis (HP:0001948)1.80135391
134Abnormality of proline metabolism (HP:0010907)1.79538879
135Hydroxyprolinuria (HP:0003080)1.79538879
136Bronchiectasis (HP:0002110)1.79330958
137Abnormal enzyme/coenzyme activity (HP:0012379)1.77374932
138Status epilepticus (HP:0002133)1.77354156
139Hyperglycemia (HP:0003074)1.77007154
140Congenital stationary night blindness (HP:0007642)1.76591644
141Acute hepatic failure (HP:0006554)1.76145209
142Congenital hepatic fibrosis (HP:0002612)1.74408350
143Azoospermia (HP:0000027)1.73542498
144Decreased circulating renin level (HP:0003351)1.73236483
145Type II lissencephaly (HP:0007260)1.71149883
146Retinal atrophy (HP:0001105)1.70389874
147Abnormal drinking behavior (HP:0030082)1.69950961

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.86935062
2ERN14.63806621
3SIK14.37518455
4FGFR44.21950487
5ADRBK23.61458100
6TAOK33.17108438
7INSRR2.91317455
8ERBB42.64210477
9BMPR1B2.60508009
10WNK32.60225976
11MAP4K22.55718443
12WNK42.41225710
13MST1R2.35433753
14ACVR1B2.32884362
15PKN22.24754568
16MAP2K42.17429162
17ZAK1.97751096
18PIK3CG1.97695176
19TLK11.97372765
20TXK1.87884476
21FLT31.87118606
22CAMKK21.86667367
23FRK1.78583693
24LATS11.75918943
25MAPK111.75398287
26TRIB31.65682745
27TYK21.58521328
28DAPK21.49086548
29CASK1.47079011
30ABL21.42829563
31MAPK131.42104015
32PTK61.39194583
33ADRBK11.37722486
34OXSR11.35570571
35NEK91.31128627
36BRSK21.26915281
37MAP3K71.26532948
38MAPKAPK31.23641949
39KDR1.21729878
40NLK1.18653248
41MAP3K41.18228536
42PINK11.14714548
43JAK21.13964901
44TBK11.13172874
45NTRK31.11780567
46FGFR21.11709944
47DYRK21.11237816
48PAK31.11059328
49PRKAA21.10579218
50STK391.10500432
51MST41.08740583
52MAP3K141.02141441
53GRK61.01899739
54PRKCE1.01860585
55STK38L0.99662820
56MAP2K30.97387945
57PNCK0.93319011
58JAK10.91029167
59PRKCZ0.90782047
60ERBB20.89276578
61MAPK40.88205859
62IRAK30.85273499
63MAPK150.85019268
64MET0.84523438
65TNK20.80822915
66MAP3K30.80247353
67PRKACA0.80074238
68MAP2K60.79375162
69MAPK120.78931981
70MAP2K20.77589578
71CAMK1D0.77093431
72MUSK0.76888859
73BCR0.76357221
74MAP3K100.75609891
75MAP3K110.74031277
76TIE10.72959975
77TGFBR10.72743157
78PRKACG0.72666508
79PIK3CA0.72584070
80CDK60.70547080
81EPHA30.70390319
82DYRK1B0.68352669
83CSK0.67952659
84CAMK2G0.67617574
85PTK2B0.67487916
86MAPKAPK50.67219821
87NME10.66032695
88EPHB10.65582806
89GRK70.63645632
90PRKAA10.63534224
91IKBKE0.61461705
92MAP2K10.61453509
93TNIK0.61315229
94MKNK20.58507248
95PRKG10.58461022
96GSK3A0.58061832
97CAMKK10.57922202
98TAOK20.57762808
99MAP2K70.57145669
100FER0.55940051
101RIPK10.55683430
102IKBKB0.55350209
103PHKG10.54831738
104PHKG20.54831738
105PDPK10.54407246
106CAMK2A0.53231560
107CSNK1G20.52932462
108DYRK1A0.52711320
109MAPK70.52289164
110TGFBR20.51943060
111STK110.51589405
112CSNK1A10.50812140
113SGK30.50362093
114GRK10.50000134
115KIT0.49261622
116CAMK10.49026184
117PRKCQ0.48731505
118PTK20.47853257
119PRKCI0.46924690
120TEC0.46172674
121EPHA40.44762052
122CSF1R0.44150915
123STK160.43861531
124MAP3K50.43768598
125TRPM70.43623511
126CSNK1D0.42131892
127FGFR30.41987845
128IGF1R0.41694929
129SGK10.40298970
130CDK40.38716065
131SGK20.38456032
132CSNK1G10.38313178
133RPS6KA50.37892814
134RET0.37816131
135MAP3K60.36705313
136ERBB30.35889770
137CSNK1G30.35783188
138PRKCG0.35326795
139EIF2AK30.34931123
140PDK10.34796876
141PLK20.34669081
142ITK0.34220257
143WEE10.34119935
144CHUK0.34051465
145GRK50.32143442
146MAP3K130.32132333
147MTOR0.31662983
148PKN10.29760662
149CAMK40.28905916
150EGFR0.28551237
151IRAK20.28132680
152MAP3K10.27708096
153SGK2230.27667246
154SGK4940.27667246
155PRKCA0.27246509
156ICK0.25395163
157PBK0.25041434
158NUAK10.25018170
159IRAK10.23441063
160CAMK1G0.21444606
161ABL10.20767531
162MAPK30.20342795
163ZAP700.19930559
164PRKACB0.19364373
165LATS20.19167035

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.43659613
2Nitrogen metabolism_Homo sapiens_hsa009103.43777245
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.38559455
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.27615356
5Arginine biosynthesis_Homo sapiens_hsa002203.00340341
6Complement and coagulation cascades_Homo sapiens_hsa046102.69580411
7Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.67944241
8Tryptophan metabolism_Homo sapiens_hsa003802.65429210
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.62452751
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.58209738
11Fatty acid degradation_Homo sapiens_hsa000712.48204582
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.45656083
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.26585763
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.16964205
15Butanoate metabolism_Homo sapiens_hsa006502.15266483
16Peroxisome_Homo sapiens_hsa041462.04425348
17Chemical carcinogenesis_Homo sapiens_hsa052041.98308440
18Propanoate metabolism_Homo sapiens_hsa006401.97974722
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.96150729
20Steroid hormone biosynthesis_Homo sapiens_hsa001401.90657573
21Histidine metabolism_Homo sapiens_hsa003401.89897021
22PPAR signaling pathway_Homo sapiens_hsa033201.83645337
23Fatty acid metabolism_Homo sapiens_hsa012121.80380983
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.75565486
25beta-Alanine metabolism_Homo sapiens_hsa004101.71325774
26Retinol metabolism_Homo sapiens_hsa008301.70468086
27Staphylococcus aureus infection_Homo sapiens_hsa051501.70373996
28Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.69034158
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.68959461
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.66211345
31Caffeine metabolism_Homo sapiens_hsa002321.63172772
32Selenocompound metabolism_Homo sapiens_hsa004501.54306461
33Phenylalanine metabolism_Homo sapiens_hsa003601.50564507
342-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.49192417
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.48396397
36Bile secretion_Homo sapiens_hsa049761.47625783
37Fat digestion and absorption_Homo sapiens_hsa049751.45705296
38Sulfur metabolism_Homo sapiens_hsa009201.42864606
39Tyrosine metabolism_Homo sapiens_hsa003501.40108168
40Pyruvate metabolism_Homo sapiens_hsa006201.37880745
41Fatty acid elongation_Homo sapiens_hsa000621.32768606
42Folate biosynthesis_Homo sapiens_hsa007901.32561619
43Starch and sucrose metabolism_Homo sapiens_hsa005001.32252210
44Cysteine and methionine metabolism_Homo sapiens_hsa002701.31177279
45Steroid biosynthesis_Homo sapiens_hsa001001.22006421
46Biosynthesis of amino acids_Homo sapiens_hsa012301.20622864
47ABC transporters_Homo sapiens_hsa020101.16750532
48Carbon metabolism_Homo sapiens_hsa012001.12945389
49Maturity onset diabetes of the young_Homo sapiens_hsa049501.11901537
50Cyanoamino acid metabolism_Homo sapiens_hsa004601.08168181
51Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.05298950
52Arginine and proline metabolism_Homo sapiens_hsa003300.99611670
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.99029591
54Vitamin B6 metabolism_Homo sapiens_hsa007500.97631471
55Sulfur relay system_Homo sapiens_hsa041220.96293433
56Vitamin digestion and absorption_Homo sapiens_hsa049770.94816481
57Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.86653916
58Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.82081758
59Glycerolipid metabolism_Homo sapiens_hsa005610.79790800
60Lysine degradation_Homo sapiens_hsa003100.76796439
61One carbon pool by folate_Homo sapiens_hsa006700.76648055
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.69623702
63Glutathione metabolism_Homo sapiens_hsa004800.68990052
64Pentose phosphate pathway_Homo sapiens_hsa000300.58203436
65Phototransduction_Homo sapiens_hsa047440.51782188
66Fatty acid biosynthesis_Homo sapiens_hsa000610.50727319
67Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.50122362
68Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.47765884
69Metabolic pathways_Homo sapiens_hsa011000.47758163
70Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.39364915
71alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.36936769
72Prion diseases_Homo sapiens_hsa050200.32677411
73Linoleic acid metabolism_Homo sapiens_hsa005910.31774618
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.29760058
75Fructose and mannose metabolism_Homo sapiens_hsa000510.29597735
76Serotonergic synapse_Homo sapiens_hsa047260.29024802
77Galactose metabolism_Homo sapiens_hsa000520.28429446
78Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.27592148
79Oxidative phosphorylation_Homo sapiens_hsa001900.22309698
80Insulin resistance_Homo sapiens_hsa049310.19684554
81Adipocytokine signaling pathway_Homo sapiens_hsa049200.18713966
82Glycerophospholipid metabolism_Homo sapiens_hsa005640.17916515
83Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.17067337
84Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.16620765
85Mineral absorption_Homo sapiens_hsa049780.16462262
86Protein export_Homo sapiens_hsa030600.15270964
87Nicotine addiction_Homo sapiens_hsa050330.11750065
88Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.07563817
89Glucagon signaling pathway_Homo sapiens_hsa049220.06989256
90Parkinsons disease_Homo sapiens_hsa050120.05189397
91Pertussis_Homo sapiens_hsa051330.01729197
92GABAergic synapse_Homo sapiens_hsa047270.01331700
93Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.00720927
94Taste transduction_Homo sapiens_hsa047420.00417003
95Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.00313820
96Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.2523626
97Thyroid hormone synthesis_Homo sapiens_hsa04918-0.2065953
98Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2037029
99Ether lipid metabolism_Homo sapiens_hsa00565-0.1976760
100Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1813061
101Hepatitis C_Homo sapiens_hsa05160-0.1747894
102Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1698917
103Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1597824
104Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1524503
105African trypanosomiasis_Homo sapiens_hsa05143-0.1325753
106Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.1253049
107Pancreatic secretion_Homo sapiens_hsa04972-0.1209790
108Renin-angiotensin system_Homo sapiens_hsa04614-0.1205709
109Insulin signaling pathway_Homo sapiens_hsa04910-0.1152751
110Regulation of autophagy_Homo sapiens_hsa04140-0.1142341
111Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1103390
112Protein digestion and absorption_Homo sapiens_hsa04974-0.0953932
113Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.0839411
114Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0814095
115Insulin secretion_Homo sapiens_hsa04911-0.0761373
116Sphingolipid metabolism_Homo sapiens_hsa00600-0.0580370
117Circadian rhythm_Homo sapiens_hsa04710-0.0238660
118Huntingtons disease_Homo sapiens_hsa05016-0.0176064
119Intestinal immune network for IgA production_Homo sapiens_hsa04672-0.0077451
120AMPK signaling pathway_Homo sapiens_hsa04152-0.0042187

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