HSDL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1actin-myosin filament sliding (GO:0033275)6.79446281
2muscle filament sliding (GO:0030049)6.79446281
3actin-mediated cell contraction (GO:0070252)5.80557697
4fatty acid beta-oxidation (GO:0006635)5.28958416
5positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.27964999
6alpha-linolenic acid metabolic process (GO:0036109)5.25721122
7fatty acid transmembrane transport (GO:1902001)5.21305140
8erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.16905687
9L-phenylalanine catabolic process (GO:0006559)5.16905687
10carnitine shuttle (GO:0006853)5.16747317
11sarcoplasmic reticulum calcium ion transport (GO:0070296)5.14390384
12lysine catabolic process (GO:0006554)5.13429752
13lysine metabolic process (GO:0006553)5.13429752
14regulation of relaxation of muscle (GO:1901077)5.11836810
15sarcomere organization (GO:0045214)4.96020124
16L-phenylalanine metabolic process (GO:0006558)4.95068281
17erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.95068281
18regulation of sequestering of triglyceride (GO:0010889)4.93481986
19fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.82872749
20myofibril assembly (GO:0030239)4.82827352
21fatty acid oxidation (GO:0019395)4.78795026
22regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.75675780
23lipid oxidation (GO:0034440)4.72394414
24fatty acid catabolic process (GO:0009062)4.72285636
25triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.67328888
26regulation of triglyceride catabolic process (GO:0010896)4.66014179
27cardiac myofibril assembly (GO:0055003)4.65520534
28creatine metabolic process (GO:0006600)4.65025762
29tricarboxylic acid cycle (GO:0006099)4.58174237
30acetyl-CoA metabolic process (GO:0006084)4.55989720
31glyoxylate metabolic process (GO:0046487)4.51750847
322-oxoglutarate metabolic process (GO:0006103)4.51020962
33amino-acid betaine metabolic process (GO:0006577)4.50532478
34short-chain fatty acid metabolic process (GO:0046459)4.50488930
35actin filament-based movement (GO:0030048)4.44593417
36aromatic amino acid family catabolic process (GO:0009074)4.40007576
37branched-chain amino acid catabolic process (GO:0009083)4.39703571
38carnitine metabolic process (GO:0009437)4.36753902
39biotin metabolic process (GO:0006768)4.33973296
40cellular ketone body metabolic process (GO:0046950)4.33663621
41carnitine transmembrane transport (GO:1902603)4.33638375
42valine metabolic process (GO:0006573)4.32019881
43regulation of actin filament-based movement (GO:1903115)4.31011974
44aspartate family amino acid catabolic process (GO:0009068)4.29470138
45monocarboxylic acid catabolic process (GO:0072329)4.29071265
46positive regulation of fatty acid beta-oxidation (GO:0032000)4.26670141
47regulation of skeletal muscle contraction (GO:0014819)4.24887360
48oxaloacetate metabolic process (GO:0006107)4.22511328
49amino-acid betaine transport (GO:0015838)4.19823572
50carnitine transport (GO:0015879)4.19823572
51cardiac muscle contraction (GO:0060048)4.19129787
52glycogen catabolic process (GO:0005980)4.18380889
53positive regulation of fatty acid oxidation (GO:0046321)4.15865030
54kynurenine metabolic process (GO:0070189)4.13798241
55sulfur amino acid catabolic process (GO:0000098)4.13028245
56bile acid biosynthetic process (GO:0006699)4.12908686
57regulation of fatty acid oxidation (GO:0046320)4.10450269
58branched-chain amino acid metabolic process (GO:0009081)4.08641064
59striated muscle contraction (GO:0006941)4.08109702
60regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO4.08074625
61cysteine metabolic process (GO:0006534)4.05882178
62glucan catabolic process (GO:0009251)4.05771880
63response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.04629485
64negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.95919994
65skeletal muscle contraction (GO:0003009)3.94776480
66actomyosin structure organization (GO:0031032)3.90594163
67regulation of cell communication by electrical coupling (GO:0010649)3.87456961
68cellular polysaccharide catabolic process (GO:0044247)3.87233250
69regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.86405451
70regulation of cholesterol metabolic process (GO:0090181)3.78358938
71indole-containing compound catabolic process (GO:0042436)3.77963344
72indolalkylamine catabolic process (GO:0046218)3.77963344
73tryptophan catabolic process (GO:0006569)3.77963344
74ethanol oxidation (GO:0006069)3.75607576
75ketone body metabolic process (GO:1902224)3.75329675
76positive regulation of lipid catabolic process (GO:0050996)3.73873985
77thioester biosynthetic process (GO:0035384)3.70573465
78acyl-CoA biosynthetic process (GO:0071616)3.70573465
79regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.69967930
80organic acid catabolic process (GO:0016054)3.62704757
81carboxylic acid catabolic process (GO:0046395)3.62704757
82plasma lipoprotein particle clearance (GO:0034381)3.62647030
83complement activation, alternative pathway (GO:0006957)3.61336595
84alpha-amino acid catabolic process (GO:1901606)3.60817629
85succinate metabolic process (GO:0006105)3.60752257
86response to mercury ion (GO:0046689)3.60577213
87triglyceride homeostasis (GO:0070328)3.57153716
88acylglycerol homeostasis (GO:0055090)3.57153716
89high-density lipoprotein particle remodeling (GO:0034375)3.56940083
90tryptophan metabolic process (GO:0006568)3.55734780
91negative regulation of potassium ion transmembrane transport (GO:1901380)3.55203284
92serine family amino acid catabolic process (GO:0009071)3.54922146
93acyl-CoA metabolic process (GO:0006637)3.54673720
94thioester metabolic process (GO:0035383)3.54673720
95tricarboxylic acid metabolic process (GO:0072350)3.53698648
96triglyceride catabolic process (GO:0019433)3.51673182
97gluconeogenesis (GO:0006094)3.49189911
98regulation of fatty acid beta-oxidation (GO:0031998)3.49012079
99urea metabolic process (GO:0019627)3.48672421
100urea cycle (GO:0000050)3.48672421
101cellular amino acid catabolic process (GO:0009063)3.48338165
102quaternary ammonium group transport (GO:0015697)3.48083654
103bile acid metabolic process (GO:0008206)3.45676613
104homocysteine metabolic process (GO:0050667)3.44584178
105polysaccharide catabolic process (GO:0000272)3.44009066
106regulation of acyl-CoA biosynthetic process (GO:0050812)3.41488969
107regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.40631621
108regulation of protein activation cascade (GO:2000257)3.40011475
109negative regulation of fatty acid biosynthetic process (GO:0045717)3.39947243
110neutral lipid catabolic process (GO:0046461)3.39277294
111acylglycerol catabolic process (GO:0046464)3.39277294
112negative regulation of protein activation cascade (GO:2000258)3.37362704
113fat-soluble vitamin biosynthetic process (GO:0042362)3.37219390
114response to muscle activity (GO:0014850)3.35096921
115regulation of cholesterol esterification (GO:0010872)3.33121436
116low-density lipoprotein particle clearance (GO:0034383)3.32268690
117cardiac muscle tissue morphogenesis (GO:0055008)3.32189971
118plasma lipoprotein particle remodeling (GO:0034369)3.31567090
119protein-lipid complex remodeling (GO:0034368)3.31567090
120macromolecular complex remodeling (GO:0034367)3.31567090
121cardiac muscle hypertrophy (GO:0003300)3.30827951
122nitrogen cycle metabolic process (GO:0071941)3.29762184
123negative regulation of lipase activity (GO:0060192)3.28613927
124coenzyme catabolic process (GO:0009109)3.28257159
125peptidyl-glutamic acid carboxylation (GO:0017187)3.27545673
126protein carboxylation (GO:0018214)3.27545673
127phospholipid homeostasis (GO:0055091)3.27240091
128hexose biosynthetic process (GO:0019319)3.26056860
129very long-chain fatty acid metabolic process (GO:0000038)3.25692608
130negative regulation of fibrinolysis (GO:0051918)3.23468338
131heart contraction (GO:0060047)3.23036820
132heart process (GO:0003015)3.23036820
133NADH metabolic process (GO:0006734)3.22022088
134regulation of complement activation (GO:0030449)3.21340248
135lipid particle organization (GO:0034389)3.21220244
136reverse cholesterol transport (GO:0043691)3.21173986
137fatty-acyl-CoA biosynthetic process (GO:0046949)3.20439011
138glucan biosynthetic process (GO:0009250)3.19177384
139glycogen biosynthetic process (GO:0005978)3.19177384
140positive regulation of triglyceride metabolic process (GO:0090208)3.19075130
141fructose metabolic process (GO:0006000)3.18063668
142muscle tissue morphogenesis (GO:0060415)3.14950188
143striated muscle hypertrophy (GO:0014897)3.14892307
144fatty acid homeostasis (GO:0055089)3.12855545
145dicarboxylic acid biosynthetic process (GO:0043650)3.12515749
146aromatic amino acid family metabolic process (GO:0009072)3.11808445
147negative regulation of complement activation (GO:0045916)3.10773040
148muscle contraction (GO:0006936)3.02209879
149regulation of the force of heart contraction (GO:0002026)2.98580010
150monosaccharide biosynthetic process (GO:0046364)2.98420406
151epoxygenase P450 pathway (GO:0019373)2.96273553
152regulation of striated muscle contraction (GO:0006942)2.86133910
153polyketide metabolic process (GO:0030638)2.85915743
154doxorubicin metabolic process (GO:0044598)2.85915743
155daunorubicin metabolic process (GO:0044597)2.85915743
156ventricular cardiac muscle tissue morphogenesis (GO:0055010)2.82681832
157cellular response to epinephrine stimulus (GO:0071872)2.81603333
158response to epinephrine (GO:0071871)2.79671092
159glycogen metabolic process (GO:0005977)2.76641030

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse8.80520909
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse8.13009407
3RXR_22158963_ChIP-Seq_LIVER_Mouse6.15196948
4PPARA_22158963_ChIP-Seq_LIVER_Mouse5.36039522
5LXR_22158963_ChIP-Seq_LIVER_Mouse4.97101481
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.30252257
7EGR1_23403033_ChIP-Seq_LIVER_Mouse4.28075618
8* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.93999852
9NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.29433822
10AR_21909140_ChIP-Seq_LNCAP_Human3.04721086
11CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.02201270
12CLOCK_20551151_ChIP-Seq_293T_Human2.36708716
13CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.13069160
14* ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.08430537
15PRDM5_23873026_ChIP-Seq_MEFs_Mouse2.06340368
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.99753707
17NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.94926096
18GATA1_22025678_ChIP-Seq_K562_Human1.86063514
19EP300_21415370_ChIP-Seq_HL-1_Mouse1.81203502
20TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.64303316
21TBX20_22328084_ChIP-Seq_HEART_Mouse1.60115258
22TBX20_22080862_ChIP-Seq_HEART_Mouse1.60115258
23RARG_19884340_ChIP-ChIP_MEFs_Mouse1.57168308
24ZNF263_19887448_ChIP-Seq_K562_Human1.55010049
25SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.51164980
26ESR1_20079471_ChIP-ChIP_T-47D_Human1.50174675
27HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.46897644
28ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.45130834
29STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.38578650
30FOXA2_19822575_ChIP-Seq_HepG2_Human1.38045480
31* PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.34120706
32* PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.28994301
33TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.28857615
34WT1_19549856_ChIP-ChIP_CCG9911_Human1.28523431
35ESR2_21235772_ChIP-Seq_MCF-7_Human1.27008994
36SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.25843020
37PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.23445543
38THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.19039994
39SOX17_20123909_ChIP-Seq_XEN_Mouse1.14274609
40RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.12640368
41HTT_18923047_ChIP-ChIP_STHdh_Human1.11958362
42E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.11781130
43BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.11437776
44* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.09253025
45CDX2_19796622_ChIP-Seq_MESCs_Mouse1.08331171
46EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.07263195
47EOMES_21245162_ChIP-Seq_HESCs_Human1.07227475
48ZFX_18555785_ChIP-Seq_MESCs_Mouse1.07089064
49TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06411456
50STAT3_1855785_ChIP-Seq_MESCs_Mouse1.06240158
51KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.04434462
52PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03278487
53AUTS2_25519132_ChIP-Seq_293T-REX_Human1.03247554
54GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00441217
55* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.00055035
56* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.00055035
57* HNF4A_19822575_ChIP-Seq_HepG2_Human0.99340402
58BCAT_22108803_ChIP-Seq_LS180_Human0.97630973
59ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.97377449
60PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.97228881
61CTNNB1_20460455_ChIP-Seq_HCT116_Human0.96577585
62FOXM1_26456572_ChIP-Seq_MCF-7_Human0.96291076
63FOXO3_23340844_ChIP-Seq_DLD1_Human0.95463107
64CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.95132234
65SOX2_27498859_Chip-Seq_STOMACH_Mouse0.95094714
66* SRF_21415370_ChIP-Seq_HL-1_Mouse0.93621721
67ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.92387267
68EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.91935148
69KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.90925699
70NRF2_20460467_ChIP-Seq_MEFs_Mouse0.90532941
71NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.90532941
72FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.90321009
73* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.88980641
74CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.87937255
75STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.86955213
76KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.86196723
77SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85968415
78HIF1A_21447827_ChIP-Seq_MCF-7_Human0.85236154
79TCF4_18268006_ChIP-ChIP_LS174T_Human0.84387451
80BP1_19119308_ChIP-ChIP_Hs578T_Human0.83581206
81AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.83489467
82TFEB_21752829_ChIP-Seq_HELA_Human0.83165725
83* GATA6_25053715_ChIP-Seq_YYC3_Human0.80839684
84POU3F2_20337985_ChIP-ChIP_501MEL_Human0.80815385
85EZH2_27294783_Chip-Seq_NPCs_Mouse0.80142736
86BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.80087220
87TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.80013111
88TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.79369151
89E2F7_22180533_ChIP-Seq_HELA_Human0.79338268
90GATA4_25053715_ChIP-Seq_YYC3_Human0.78693297
91SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.77938757
92GATA2_19941826_ChIP-Seq_K562_Human0.75759756
93PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.75586691
94GATA1_19941826_ChIP-Seq_K562_Human0.74363225
95SALL4_18804426_ChIP-ChIP_XEN_Mouse0.71146769
96FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.70842826
97CBP_21632823_ChIP-Seq_H3396_Human0.70765438
98CJUN_26792858_Chip-Seq_BT549_Human0.70342188
99SOX9_24532713_ChIP-Seq_HFSC_Mouse0.70336638
100* IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.68847739
101RAD21_21589869_ChIP-Seq_MESCs_Mouse0.68782782
102TRIM28_21343339_ChIP-Seq_HEK293_Human0.67906199
103CEBPB_22108803_ChIP-Seq_LS180_Human0.67444734
104FOXA1_25552417_ChIP-Seq_VCAP_Human0.67068839
105CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.66233035
106ESR1_21235772_ChIP-Seq_MCF-7_Human0.65809067
107Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.65184211
108EGR1_19032775_ChIP-ChIP_M12_Human0.64732890
109MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.64659007
110RXRA_24833708_ChIP-Seq_LIVER_Mouse0.64411921
111* CDX2_22108803_ChIP-Seq_LS180_Human0.63647332
112ERG_20517297_ChIP-Seq_VCAP_Human0.63544607
113RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.62356611
114P63_26484246_Chip-Seq_KERATINOCYTES_Human0.61564550
115GATA2_21666600_ChIP-Seq_HMVEC_Human0.60993539
116SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.60892882
117NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.60638764
118NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.59903436
119GATA4_21415370_ChIP-Seq_HL-1_Mouse0.59513329
120LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.58142832
121SOX2_20726797_ChIP-Seq_SW620_Human0.56452004
122TP63_23658742_ChIP-Seq_EP156T_Human0.56408394
123OCT4_20526341_ChIP-Seq_ESCs_Human0.55410293
124GATA3_24758297_ChIP-Seq_MCF-7_Human0.55291414
125ESET_19884257_ChIP-Seq_ESCs_Mouse0.53939305
126AR_20517297_ChIP-Seq_VCAP_Human0.52175360
127ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.51851702
128KAP1_22055183_ChIP-Seq_ESCs_Mouse0.50820568
129NR3C1_23031785_ChIP-Seq_PC12_Mouse0.50524195
130CSB_26484114_Chip-Seq_FIBROBLAST_Human0.50454116
131BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.48899722
132STAT1_17558387_ChIP-Seq_HELA_Human0.48445511
133P53_21459846_ChIP-Seq_SAOS-2_Human0.47060020
134PIAS1_25552417_ChIP-Seq_VCAP_Human0.46843168
135GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.46601746
136FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.45670589
137PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.45474873

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system5.54892655
2MP0005360_urolithiasis5.00531040
3MP0005365_abnormal_bile_salt4.43188075
4MP0005085_abnormal_gallbladder_physiolo4.41475879
5MP0002837_dystrophic_cardiac_calcinosis3.74636523
6MP0008875_abnormal_xenobiotic_pharmacok3.44153478
7MP0004145_abnormal_muscle_electrophysio3.24906372
8MP0003806_abnormal_nucleotide_metabolis3.13148546
9MP0003646_muscle_fatigue3.13110739
10MP0004130_abnormal_muscle_cell3.04895167
11MP0010329_abnormal_lipoprotein_level2.92751960
12MP0005670_abnormal_white_adipose2.84825220
13MP0003252_abnormal_bile_duct2.56871627
14MP0005332_abnormal_amino_acid2.52560746
15MP0005666_abnormal_adipose_tissue2.38464149
16MP0004084_abnormal_cardiac_muscle2.33120316
17MP0009840_abnormal_foam_cell2.31515445
18MP0004215_abnormal_myocardial_fiber2.28507978
19MP0003195_calcinosis2.15361320
20MP0002118_abnormal_lipid_homeostasis2.13035974
21MP0005330_cardiomyopathy2.11246100
22MP0006036_abnormal_mitochondrial_physio2.06653315
23MP0000751_myopathy2.00576213
24MP0004036_abnormal_muscle_relaxation2.00340839
25MP0003191_abnormal_cellular_cholesterol1.89559004
26MP0005083_abnormal_biliary_tract1.83937875
27MP0005451_abnormal_body_composition1.80604033
28MP0000609_abnormal_liver_physiology1.76752550
29MP0002971_abnormal_brown_adipose1.75592755
30MP0004185_abnormal_adipocyte_glucose1.74022108
31MP0000749_muscle_degeneration1.71621391
32MP0005319_abnormal_enzyme/_coenzyme1.65486940
33MP0001666_abnormal_nutrient_absorption1.61882550
34MP0005584_abnormal_enzyme/coenzyme_acti1.61828074
35MP0004087_abnormal_muscle_fiber1.54860270
36MP0002972_abnormal_cardiac_muscle1.53988270
37MP0008775_abnormal_heart_ventricle1.53610103
38MP0005375_adipose_tissue_phenotype1.46144864
39MP0005385_cardiovascular_system_phenoty1.44225315
40MP0001544_abnormal_cardiovascular_syste1.44225315
41MP0005620_abnormal_muscle_contractility1.38342329
42MP0006138_congestive_heart_failure1.33641545
43MP0003186_abnormal_redox_activity1.30975303
44MP0009643_abnormal_urine_homeostasis1.28609632
45MP0005535_abnormal_body_temperature1.25735781
46MP0009780_abnormal_chondrocyte_physiolo1.22709996
47MP0004510_myositis1.22656818
48MP0004272_abnormal_basement_membrane1.21515325
49MP0010630_abnormal_cardiac_muscle1.20672870
50MP0004019_abnormal_vitamin_homeostasis1.19372404
51MP0003137_abnormal_impulse_conducting1.19107777
52MP0002269_muscular_atrophy1.17811762
53MP0003656_abnormal_erythrocyte_physiolo1.14536319
54MP0005408_hypopigmentation1.12631814
55MP0003011_delayed_dark_adaptation1.11651568
56MP0005334_abnormal_fat_pad1.11313125
57MP0001764_abnormal_homeostasis1.10063679
58MP0002078_abnormal_glucose_homeostasis1.06960895
59MP0000750_abnormal_muscle_regeneration1.06726623
60MP0003221_abnormal_cardiomyocyte_apopto1.06363306
61MP0002108_abnormal_muscle_morphology1.06242440
62MP0010234_abnormal_vibrissa_follicle1.04755492
63MP0004043_abnormal_pH_regulation1.04172413
64MP0003690_abnormal_glial_cell1.03656389
65MP0006035_abnormal_mitochondrial_morpho1.01673831
66MP0002877_abnormal_melanocyte_morpholog1.00927360
67MP0004484_altered_response_of0.99714883
68MP0000747_muscle_weakness0.99238409
69MP0000733_abnormal_muscle_development0.98523167
70MP0002332_abnormal_exercise_endurance0.96284329
71MP0002106_abnormal_muscle_physiology0.95400663
72MP0002796_impaired_skin_barrier0.94924979
73MP0005647_abnormal_sex_gland0.93975931
74MP0005248_abnormal_Harderian_gland0.93626142
75MP0004085_abnormal_heartbeat0.92347228
76MP0005266_abnormal_metabolism0.91712784
77MP0004147_increased_porphyrin_level0.88702694
78MP0002138_abnormal_hepatobiliary_system0.87871695
79MP0003941_abnormal_skin_development0.87025316
80MP0000230_abnormal_systemic_arterial0.86784536
81MP0009115_abnormal_fat_cell0.86079229
82MP0001661_extended_life_span0.84160840
83MP0008438_abnormal_cutaneous_collagen0.83879772
84MP0003329_amyloid_beta_deposits0.82635038
85MP0000759_abnormal_skeletal_muscle0.82419682
86MP0000604_amyloidosis0.81840848
87MP0003705_abnormal_hypodermis_morpholog0.81800461
88MP0003566_abnormal_cell_adhesion0.80480080
89MP0002970_abnormal_white_adipose0.79834026
90MP0010352_gastrointestinal_tract_polyps0.79830932
91MP0000013_abnormal_adipose_tissue0.78882691
92MP0009697_abnormal_copulation0.78332808
93MP0005636_abnormal_mineral_homeostasis0.77891227
94MP0003868_abnormal_feces_composition0.77006150
95MP0009764_decreased_sensitivity_to0.76233869
96MP0009763_increased_sensitivity_to0.75216047
97MP0000343_altered_response_to0.74890287
98MP0000598_abnormal_liver_morphology0.74318496
99MP0005165_increased_susceptibility_to0.74242656
100MP0005369_muscle_phenotype0.73992345
101MP0000003_abnormal_adipose_tissue0.73516959
102MP0000266_abnormal_heart_morphology0.73080044
103MP0009642_abnormal_blood_homeostasis0.70475493
104MP0003828_pulmonary_edema0.70081881
105MP0005275_abnormal_skin_tensile0.69795741
106MP0002876_abnormal_thyroid_physiology0.69674363
107MP0009384_cardiac_valve_regurgitation0.69510844
108MP0005448_abnormal_energy_balance0.68828023
109MP0001756_abnormal_urination0.68804463
110MP0010368_abnormal_lymphatic_system0.68329779
111MP0001853_heart_inflammation0.68209070
112MP0005376_homeostasis/metabolism_phenot0.68073532
113MP0002254_reproductive_system_inflammat0.66657268
114MP0003950_abnormal_plasma_membrane0.66483268
115MP0002132_abnormal_respiratory_system0.64596609
116MP0002128_abnormal_blood_circulation0.64502634
117MP0001958_emphysema0.60907897
118MP0004233_abnormal_muscle_weight0.60044519
119MP0002896_abnormal_bone_mineralization0.59505693
120MP0002127_abnormal_cardiovascular_syste0.58931838
121MP0005409_darkened_coat_color0.57510116
122MP0005058_abnormal_lysosome_morphology0.56841284

Predicted human phenotypes

RankGene SetZ-score
1Muscle fiber inclusion bodies (HP:0100299)6.91933299
2Nemaline bodies (HP:0003798)6.91320741
3Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)6.75563070
4Type 1 muscle fiber predominance (HP:0003803)5.24797752
5Hypoglycemic coma (HP:0001325)4.99056670
6Abnormality of fatty-acid metabolism (HP:0004359)4.76145997
7Hyperammonemia (HP:0001987)4.69862347
8Hyperglycinuria (HP:0003108)4.60911331
9Myoglobinuria (HP:0002913)4.48689643
10EMG: myopathic abnormalities (HP:0003458)4.46111071
11Xanthomatosis (HP:0000991)4.44271799
12Ketosis (HP:0001946)4.40854586
13Intrahepatic cholestasis (HP:0001406)4.36932097
14Abnormality of aromatic amino acid family metabolism (HP:0004338)4.29222345
15Abnormality of serine family amino acid metabolism (HP:0010894)4.27458649
16Abnormality of glycine metabolism (HP:0010895)4.27458649
17Deep venous thrombosis (HP:0002625)4.22752593
18Ketoacidosis (HP:0001993)4.19088683
19Abnormality of the calf musculature (HP:0001430)4.08009588
20Hyperlipoproteinemia (HP:0010980)4.06372718
21Abnormality of dicarboxylic acid metabolism (HP:0010995)4.04466068
22Dicarboxylic aciduria (HP:0003215)4.04466068
23Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.95991075
24Bundle branch block (HP:0011710)3.89675917
25Hyperglycinemia (HP:0002154)3.73220865
26Hypoalphalipoproteinemia (HP:0003233)3.70954842
27Neck muscle weakness (HP:0000467)3.70330729
28Rhabdomyolysis (HP:0003201)3.62490219
29Centrally nucleated skeletal muscle fibers (HP:0003687)3.57381413
30Subaortic stenosis (HP:0001682)3.54678325
31Abnormality of the left ventricular outflow tract (HP:0011103)3.54678325
32Sudden death (HP:0001699)3.52038683
33Exercise-induced myalgia (HP:0003738)3.49179006
34Epidermoid cyst (HP:0200040)3.44873489
35Abnormality of skeletal muscle fiber size (HP:0012084)3.43451851
36Increased connective tissue (HP:0009025)3.41863478
37Hypobetalipoproteinemia (HP:0003563)3.40651222
38Hypolipoproteinemia (HP:0010981)3.39822756
39Generalized aminoaciduria (HP:0002909)3.38208106
40Prolonged partial thromboplastin time (HP:0003645)3.33006683
41Abnormality of monocarboxylic acid metabolism (HP:0010996)3.31802515
42Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.27459994
43Ventricular tachycardia (HP:0004756)3.27257348
44Distal arthrogryposis (HP:0005684)3.25103256
45Complement deficiency (HP:0004431)3.21324285
46Hepatic necrosis (HP:0002605)3.19486544
47Rimmed vacuoles (HP:0003805)3.19322906
48Distal lower limb muscle weakness (HP:0009053)3.18079162
49Cerebral edema (HP:0002181)3.17705383
50Increased variability in muscle fiber diameter (HP:0003557)3.13531779
51Right ventricular cardiomyopathy (HP:0011663)3.08478065
52Metabolic acidosis (HP:0001942)2.95086474
53Exercise-induced muscle cramps (HP:0003710)2.94183294
54Lethargy (HP:0001254)2.93158821
55Myopathic facies (HP:0002058)2.92551339
56Hyporeflexia of lower limbs (HP:0002600)2.89350472
57Palpitations (HP:0001962)2.84629467
58Abnormality of aspartate family amino acid metabolism (HP:0010899)2.83745280
59Abnormality of serum amino acid levels (HP:0003112)2.80961826
60Increased muscle lipid content (HP:0009058)2.78693323
61Abnormality of glutamine family amino acid metabolism (HP:0010902)2.78010679
62Ulnar deviation of the wrist (HP:0003049)2.74304743
63Proximal tubulopathy (HP:0000114)2.68808703
64Calf muscle hypertrophy (HP:0008981)2.68335657
65Lipoatrophy (HP:0100578)2.61507173
66Round ear (HP:0100830)2.61007911
67Frequent falls (HP:0002359)2.58393734
68Acute encephalopathy (HP:0006846)2.54067508
69Nausea (HP:0002018)2.51361777
70Hypercholesterolemia (HP:0003124)2.50197423
71Abnormality of methionine metabolism (HP:0010901)2.49089656
72Skin nodule (HP:0200036)2.48430878
73Abnormality of sulfur amino acid metabolism (HP:0004339)2.48257249
74Atrial fibrillation (HP:0005110)2.45826973
75Atrioventricular block (HP:0001678)2.45104166
76Vomiting (HP:0002013)2.44838547
77Renal cortical cysts (HP:0000803)2.43643865
78Muscle fiber splitting (HP:0003555)2.41172889
79Dilated cardiomyopathy (HP:0001644)2.40910879
80Muscle hypertrophy of the lower extremities (HP:0008968)2.40292530
81Areflexia of lower limbs (HP:0002522)2.40112930
82Syncope (HP:0001279)2.39424738
83Abnormality of the common coagulation pathway (HP:0010990)2.34838030
84EMG: neuropathic changes (HP:0003445)2.31369426
85Abnormality of purine metabolism (HP:0004352)2.30868643
86Abnormality of glycolysis (HP:0004366)2.30714819
87Increased serum pyruvate (HP:0003542)2.30714819
88Hyperinsulinemic hypoglycemia (HP:0000825)2.26260067
89Hyperbilirubinemia (HP:0002904)2.25324139
90Primary atrial arrhythmia (HP:0001692)2.23739474
91Fat malabsorption (HP:0002630)2.22924091
92Hepatocellular necrosis (HP:0001404)2.22683543
93Calcaneovalgus deformity (HP:0001848)2.22457198
94Cholelithiasis (HP:0001081)2.22042535
95Abnormal gallbladder morphology (HP:0012437)2.21702224
96Lactic acidosis (HP:0003128)2.19747475
97Abnormality of complement system (HP:0005339)2.19093224
98Absent phalangeal crease (HP:0006109)2.16719492
99Mildly elevated creatine phosphokinase (HP:0008180)2.16443444
100Muscle stiffness (HP:0003552)2.15910018
101Methylmalonic aciduria (HP:0012120)2.15098290
102Generalized muscle weakness (HP:0003324)2.14955220
103Heart block (HP:0012722)2.14486260
104Joint hemorrhage (HP:0005261)2.14374598
105Asymmetric septal hypertrophy (HP:0001670)2.14313737
106Abnormal mitochondria in muscle tissue (HP:0008316)2.13621828
107Supraventricular tachycardia (HP:0004755)2.13496682
108Gowers sign (HP:0003391)2.12843371
109Hypertriglyceridemia (HP:0002155)2.11628001
110Hypoglycemic seizures (HP:0002173)2.11351166
111Abnormality of the foot musculature (HP:0001436)2.09810769
112Supraventricular arrhythmia (HP:0005115)2.09044944
113Delayed CNS myelination (HP:0002188)2.08533791
114Abnormality of urine glucose concentration (HP:0011016)2.07849099
115Glycosuria (HP:0003076)2.07849099
116Conjunctival hamartoma (HP:0100780)2.07596549
117Scapular winging (HP:0003691)2.04888649
118Abnormality of the intrinsic pathway (HP:0010989)2.04290464
119Late onset (HP:0003584)2.04165465
120Difficulty running (HP:0009046)2.03778621
121Gout (HP:0001997)2.01727664
122Abnormal atrioventricular conduction (HP:0005150)2.00587542
123Abnormality of alanine metabolism (HP:0010916)2.00555524
124Hyperalaninemia (HP:0003348)2.00555524
125Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.00555524
126Mitral stenosis (HP:0001718)2.00536388
127Hyperglycemia (HP:0003074)2.00380734
128Ventricular arrhythmia (HP:0004308)2.00098226
129Oligomenorrhea (HP:0000876)1.98800809
130Distal lower limb amyotrophy (HP:0008944)1.98663746
131Myotonia (HP:0002486)1.98233205
132Ragged-red muscle fibers (HP:0003200)1.97577056
133Acute necrotizing encephalopathy (HP:0006965)1.96936955
134Foot dorsiflexor weakness (HP:0009027)1.94873183
135Limb-girdle muscle atrophy (HP:0003797)1.92898468
136Reduced antithrombin III activity (HP:0001976)1.91512110
137Progressive muscle weakness (HP:0003323)1.88468179
138Abnormal finger flexion creases (HP:0006143)1.85978329
139Deformed tarsal bones (HP:0008119)1.84922758
140Spinal rigidity (HP:0003306)1.84027177
141Malignant hyperthermia (HP:0002047)1.83717131
142Pheochromocytoma (HP:0002666)1.80784671

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK5.54626938
2PDK44.53043806
3PDK34.53043806
4TRIB33.48475532
5LMTK22.85889436
6PDK22.74253789
7TTN2.62548770
8SIK12.45466618
9OBSCN2.38988227
10STK242.30450783
11PKN22.25667714
12PHKG22.24137845
13PHKG12.24137845
14EIF2AK12.16691783
15INSRR2.15408137
16MYLK2.10608163
17PBK2.06819069
18ERN11.87676154
19FGFR41.87092956
20PINK11.79940987
21SCYL21.78894046
22STK391.59196418
23WNK41.51043028
24EPHB11.49798903
25PRKAA21.48777211
26CAMK1D1.46915047
27PIK3CA1.39242224
28NEK91.27639143
29TIE11.26997325
30MUSK1.24201590
31ERBB31.19275146
32PIK3CG1.17779866
33MST1R1.16666233
34MAPKAPK31.08659611
35FLT31.08508577
36NEK11.04723933
37RAF11.04603065
38EIF2AK31.03030803
39LATS21.02861371
40EEF2K1.01091353
41LIMK11.00169466
42PDGFRA0.98494310
43CCNB10.97762756
44BRSK20.96785527
45PRKAA10.95117776
46DMPK0.92131165
47MOS0.92098015
48MAP3K120.89867544
49PDPK10.89649491
50MAP3K70.89644770
51FGFR20.89012910
52MAP3K20.87988411
53PTK60.87951353
54ERBB40.87762023
55STK38L0.87354037
56PRKD10.85135618
57YES10.84526873
58AKT20.83100679
59LATS10.81570737
60MAPK110.80919976
61MST40.77768099
62JAK20.76218122
63PDK10.76094919
64MAP2K40.74731262
65CAMK1G0.73561123
66MAPK120.73551572
67GRK70.72996276
68PAK30.72864465
69PRKACG0.72380670
70CAMK2D0.71398668
71MAP3K30.70317450
72TTK0.70275859
73KDR0.69434054
74JAK10.68914602
75TAOK30.68515948
76RIPK10.67893591
77ROCK20.67442236
78TYK20.64544271
79WNK10.62019615
80ARAF0.61282536
81AKT30.59785666
82EPHA30.58349332
83CAMK2G0.56603564
84ILK0.56602845
85ABL20.55973377
86PAK40.55947231
87SGK30.54106566
88STK40.53909000
89OXSR10.53026377
90RET0.52770218
91WEE10.52638811
92RPS6KB20.51562093
93MAP2K30.51317254
94TGFBR20.50008950
95MET0.49873684
96MAP3K60.49588963
97PKN10.47928235
98FRK0.47754853
99PLK40.47302837
100MAP2K10.46785200
101SGK2230.46493531
102SGK4940.46493531
103LRRK20.46279255
104PTK20.46132496
105PRKCH0.45281583
106FGFR30.44865675
107TBK10.43510343
108TRPM70.43268532
109MAPK40.43253259
110MAPK70.41200151
111PRKG10.41128182
112MAP3K50.40885787
113PRKCQ0.40737139
114KSR20.40318894
115ROCK10.38967907
116PRKG20.38886419
117GSK3A0.38485726
118PRKACA0.38417966
119STK380.36161285
120SGK20.34932557
121MAPKAPK50.33353760
122FER0.32792302
123TESK10.32475332
124PRKACB0.31310630
125EIF2AK20.31269573
126ICK0.31042654
127STK30.30346193
128BRAF0.30100606
129MAP3K80.29452597
130CAMK10.29060877
131CDK60.28248032
132FGFR10.27277749
133IRAK10.27172343
134CAMK40.27079612
135IGF1R0.27039361
136MAP3K130.26199593
137PRKCE0.24892265
138CAMK2A0.24546760

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid degradation_Homo sapiens_hsa000713.61747781
2Propanoate metabolism_Homo sapiens_hsa006403.59015469
3Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.33642135
4Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.10717583
5Fatty acid metabolism_Homo sapiens_hsa012123.04391582
6Primary bile acid biosynthesis_Homo sapiens_hsa001202.94245178
7Nitrogen metabolism_Homo sapiens_hsa009102.80240836
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.74405009
9Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.71877183
10Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.66522628
112-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.66315979
12PPAR signaling pathway_Homo sapiens_hsa033202.47673104
13Butanoate metabolism_Homo sapiens_hsa006502.46421748
14Fatty acid elongation_Homo sapiens_hsa000622.29247304
15Tryptophan metabolism_Homo sapiens_hsa003802.27081608
16Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.19939175
17Pyruvate metabolism_Homo sapiens_hsa006202.18318815
18Arginine biosynthesis_Homo sapiens_hsa002202.14240235
19Peroxisome_Homo sapiens_hsa041462.04371573
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.97921565
21Carbon metabolism_Homo sapiens_hsa012001.97028269
22beta-Alanine metabolism_Homo sapiens_hsa004101.89259864
23Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.79479956
24Fatty acid biosynthesis_Homo sapiens_hsa000611.60842055
25Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.58027012
26Complement and coagulation cascades_Homo sapiens_hsa046101.57092949
27Pentose and glucuronate interconversions_Homo sapiens_hsa000401.56627440
28Sulfur metabolism_Homo sapiens_hsa009201.38820955
29Caffeine metabolism_Homo sapiens_hsa002321.38740629
30Chemical carcinogenesis_Homo sapiens_hsa052041.34379557
31Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.33646732
32Phenylalanine metabolism_Homo sapiens_hsa003601.27313348
33Starch and sucrose metabolism_Homo sapiens_hsa005001.26017638
34Histidine metabolism_Homo sapiens_hsa003401.25077086
35Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.20854759
36Biosynthesis of amino acids_Homo sapiens_hsa012301.18319051
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.15450795
38Tyrosine metabolism_Homo sapiens_hsa003501.12204253
39Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.11887941
40Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.10333407
41Steroid biosynthesis_Homo sapiens_hsa001001.09521258
42Bile secretion_Homo sapiens_hsa049761.07511492
43Steroid hormone biosynthesis_Homo sapiens_hsa001401.07345708
44Retinol metabolism_Homo sapiens_hsa008301.05971337
45Fat digestion and absorption_Homo sapiens_hsa049751.05320800
46Glycerolipid metabolism_Homo sapiens_hsa005611.03514407
47Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.00519563
48ABC transporters_Homo sapiens_hsa020100.89666333
49Selenocompound metabolism_Homo sapiens_hsa004500.87285042
50Drug metabolism - other enzymes_Homo sapiens_hsa009830.87118485
51Cysteine and methionine metabolism_Homo sapiens_hsa002700.86707486
52Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.86677160
53Staphylococcus aureus infection_Homo sapiens_hsa051500.84910238
54Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.81829961
55Adipocytokine signaling pathway_Homo sapiens_hsa049200.81694632
56Lysine degradation_Homo sapiens_hsa003100.81450444
57Arginine and proline metabolism_Homo sapiens_hsa003300.81019300
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.78672893
59Oxidative phosphorylation_Homo sapiens_hsa001900.78094677
60Vitamin B6 metabolism_Homo sapiens_hsa007500.74380048
61Parkinsons disease_Homo sapiens_hsa050120.73768406
62Cardiac muscle contraction_Homo sapiens_hsa042600.73058207
63Cyanoamino acid metabolism_Homo sapiens_hsa004600.71148390
64Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69780292
65Glutathione metabolism_Homo sapiens_hsa004800.64870006
66Pentose phosphate pathway_Homo sapiens_hsa000300.64779484
67Folate biosynthesis_Homo sapiens_hsa007900.63129972
68Insulin resistance_Homo sapiens_hsa049310.61990604
69Metabolic pathways_Homo sapiens_hsa011000.52314461
70AMPK signaling pathway_Homo sapiens_hsa041520.51617270
71Glucagon signaling pathway_Homo sapiens_hsa049220.51088786
72Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.49237803
73Alzheimers disease_Homo sapiens_hsa050100.49138817
74Sulfur relay system_Homo sapiens_hsa041220.46690189
75alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.45874030
76Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.41482607
77Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.40877333
78Dilated cardiomyopathy_Homo sapiens_hsa054140.40496575
79Vitamin digestion and absorption_Homo sapiens_hsa049770.39339246
80Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.34357009
81One carbon pool by folate_Homo sapiens_hsa006700.34277058
82Fructose and mannose metabolism_Homo sapiens_hsa000510.33564732
83Adherens junction_Homo sapiens_hsa045200.31227314
84Glycerophospholipid metabolism_Homo sapiens_hsa005640.31045522
85Focal adhesion_Homo sapiens_hsa045100.30418637
86Linoleic acid metabolism_Homo sapiens_hsa005910.30302965
87Insulin signaling pathway_Homo sapiens_hsa049100.29666693
88Galactose metabolism_Homo sapiens_hsa000520.27818744
89Huntingtons disease_Homo sapiens_hsa050160.27818714
90Other glycan degradation_Homo sapiens_hsa005110.27321403
91Tight junction_Homo sapiens_hsa045300.24898275
92Renin-angiotensin system_Homo sapiens_hsa046140.24882554
93Maturity onset diabetes of the young_Homo sapiens_hsa049500.22317660
94Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.20156466
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.13367622
96Thyroid cancer_Homo sapiens_hsa052160.13311784
97Thyroid hormone signaling pathway_Homo sapiens_hsa049190.12343251
98Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.12188453
99Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.11202825
100Mineral absorption_Homo sapiens_hsa049780.10610773
101Thyroid hormone synthesis_Homo sapiens_hsa049180.09192992
102Renin secretion_Homo sapiens_hsa049240.07444850
103Ovarian steroidogenesis_Homo sapiens_hsa049130.04995118
104Central carbon metabolism in cancer_Homo sapiens_hsa052300.03922087
105Arachidonic acid metabolism_Homo sapiens_hsa005900.01864041
106Prion diseases_Homo sapiens_hsa050200.01603851
107Longevity regulating pathway - mammal_Homo sapiens_hsa042110.01414131
108Type II diabetes mellitus_Homo sapiens_hsa04930-0.1343742
109cGMP-PKG signaling pathway_Homo sapiens_hsa04022-0.1260638
110Viral myocarditis_Homo sapiens_hsa05416-0.1234459
111Ether lipid metabolism_Homo sapiens_hsa00565-0.1204760
112Circadian rhythm_Homo sapiens_hsa04710-0.1001420
113Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261-0.0325651

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