HSF5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)9.86653176
2acrosome reaction (GO:0007340)9.75068941
3binding of sperm to zona pellucida (GO:0007339)9.29606177
4plasma membrane fusion (GO:0045026)9.04141073
5cell-cell recognition (GO:0009988)9.01208730
6epithelial cilium movement (GO:0003351)8.96605881
7synaptonemal complex organization (GO:0070193)8.77985004
8spermatid development (GO:0007286)8.77958589
9motile cilium assembly (GO:0044458)8.68308917
10cell wall macromolecule catabolic process (GO:0016998)8.67319885
11cell wall macromolecule metabolic process (GO:0044036)8.67319885
12synaptonemal complex assembly (GO:0007130)8.44305294
13reproduction (GO:0000003)8.43304210
14DNA methylation involved in gamete generation (GO:0043046)7.96848220
15cilium movement (GO:0003341)7.82189546
16epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.81122089
17regulation of cilium movement (GO:0003352)7.16931138
18single fertilization (GO:0007338)6.96772931
19male meiosis I (GO:0007141)6.71879184
20fertilization (GO:0009566)6.36614701
21sperm capacitation (GO:0048240)6.16732575
22chromosome organization involved in meiosis (GO:0070192)6.05288385
23spermatogenesis (GO:0007283)5.95485516
24male gamete generation (GO:0048232)5.93608489
25meiotic nuclear division (GO:0007126)5.87879013
26negative regulation of inclusion body assembly (GO:0090084)5.65356284
27microtubule depolymerization (GO:0007019)5.60692747
28gamete generation (GO:0007276)5.56394025
29meiosis I (GO:0007127)5.45926015
30meiotic cell cycle (GO:0051321)5.42325078
31pyrimidine deoxyribonucleotide catabolic process (GO:0009223)5.40798087
32germ cell development (GO:0007281)5.29616213
33cellular process involved in reproduction in multicellular organism (GO:0022412)5.21225609
34positive regulation of B cell differentiation (GO:0045579)4.90972981
35ventricular system development (GO:0021591)4.90629798
36pyrimidine nucleotide catabolic process (GO:0006244)4.88579892
37protein localization to cilium (GO:0061512)4.84230998
38microtubule severing (GO:0051013)4.75568152
39RNA destabilization (GO:0050779)4.68344828
40regulation of meiosis I (GO:0060631)4.65411024
41organic cation transport (GO:0015695)4.60333148
42seminiferous tubule development (GO:0072520)4.53634153
43monoubiquitinated protein deubiquitination (GO:0035520)4.50840121
44rRNA methylation (GO:0031167)4.46956124
45multicellular organismal reproductive process (GO:0048609)4.34702906
46regulation of histone H3-K9 methylation (GO:0051570)4.33325135
47regulation of inclusion body assembly (GO:0090083)4.30386428
48calcium ion-dependent exocytosis (GO:0017156)4.30216842
49rRNA modification (GO:0000154)4.26407638
50gene silencing by RNA (GO:0031047)4.22207360
51cell recognition (GO:0008037)4.20978502
52protein targeting to Golgi (GO:0000042)4.04401273
53succinate metabolic process (GO:0006105)4.00789957
54meiotic cell cycle process (GO:1903046)4.00477805
55regulation of microtubule-based movement (GO:0060632)3.95973671
56establishment of protein localization to Golgi (GO:0072600)3.94765960
57interkinetic nuclear migration (GO:0022027)3.93584863
58regulation of female gonad development (GO:2000194)3.84878199
59synapsis (GO:0007129)3.82296831
60retrograde transport, vesicle recycling within Golgi (GO:0000301)3.78000619
61left/right pattern formation (GO:0060972)3.75562735
62genitalia morphogenesis (GO:0035112)3.73284975
63base-excision repair, AP site formation (GO:0006285)3.70806992
64muscle organ morphogenesis (GO:0048644)3.70239444
65reciprocal DNA recombination (GO:0035825)3.64984982
66reciprocal meiotic recombination (GO:0007131)3.64984982
67positive regulation of growth hormone secretion (GO:0060124)3.64371520
68positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO3.60864833
69regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)3.60864833
70protein polyglutamylation (GO:0018095)3.59109157
71response to pheromone (GO:0019236)3.56192835
72regulation of centriole replication (GO:0046599)3.55026079
73peptidyl-arginine methylation (GO:0018216)3.49357624
74peptidyl-arginine N-methylation (GO:0035246)3.49357624
75spermatid nucleus differentiation (GO:0007289)3.47914776
76intraciliary transport (GO:0042073)3.46504563
77positive regulation of mitochondrial fission (GO:0090141)3.46458782
78regulation of spindle checkpoint (GO:0090231)3.41256812
79nuclear pore complex assembly (GO:0051292)3.39891477
80deoxyribonucleotide catabolic process (GO:0009264)3.39080621
81pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.38215164
82centriole replication (GO:0007099)3.37732555
83multicellular organismal development (GO:0007275)3.37279998
84peptidyl-arginine omega-N-methylation (GO:0035247)3.34219761
85positive regulation of T cell cytokine production (GO:0002726)3.31511952
86mature B cell differentiation involved in immune response (GO:0002313)3.26943233
87regulation of B cell differentiation (GO:0045577)3.25481863
88centriole assembly (GO:0098534)3.23977302
89protein kinase C signaling (GO:0070528)3.21566156
90cilium organization (GO:0044782)3.14034590
91microtubule polymerization or depolymerization (GO:0031109)3.14014100
92DNA alkylation (GO:0006305)3.10244124
93DNA methylation (GO:0006306)3.10244124
94axoneme assembly (GO:0035082)3.10117294
95positive regulation of phosphoprotein phosphatase activity (GO:0032516)3.09778321
96positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)3.08004351
97regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)3.08004351
98glomerular visceral epithelial cell development (GO:0072015)3.07685256
99deoxyribose phosphate catabolic process (GO:0046386)3.07243298
100DNA packaging (GO:0006323)3.06525040
101mitotic cell cycle arrest (GO:0071850)3.06212553
102glycerol ether metabolic process (GO:0006662)3.06118614
103positive regulation of granulocyte differentiation (GO:0030854)3.05266633
104male sex determination (GO:0030238)3.04713214
105chromosome condensation (GO:0030261)3.03132967
106cilium assembly (GO:0042384)3.00951983
107mast cell activation involved in immune response (GO:0002279)3.00364003
108mast cell degranulation (GO:0043303)3.00364003
109lactate metabolic process (GO:0006089)2.98625158
110negative regulation of organelle assembly (GO:1902116)2.97923536
111autophagic vacuole fusion (GO:0000046)2.97410475
112regulation of protein polyubiquitination (GO:1902914)2.96065711
113microtubule-based movement (GO:0007018)2.95780035
114definitive hemopoiesis (GO:0060216)2.95347704
115protein localization to Golgi apparatus (GO:0034067)2.93442225
116negative regulation of histone methylation (GO:0031061)2.93089336
117female gamete generation (GO:0007292)2.92093419
118interferon-gamma secretion (GO:0072643)2.90762805
119pore complex assembly (GO:0046931)2.89414876
120cellular response to gamma radiation (GO:0071480)2.89276850
121polyol catabolic process (GO:0046174)2.86647384
122RNA methylation (GO:0001510)2.86424869
123ether metabolic process (GO:0018904)2.82629735
124carnitine transmembrane transport (GO:1902603)2.82302443
125cellular component assembly involved in morphogenesis (GO:0010927)2.82247515
126carnitine transport (GO:0015879)2.81796975
127amino-acid betaine transport (GO:0015838)2.81796975
128regulation of mitochondrial depolarization (GO:0051900)2.81240891
129histone H3-K9 demethylation (GO:0033169)2.80041671
130protein K11-linked deubiquitination (GO:0035871)2.79306452
131cilium morphogenesis (GO:0060271)2.76825067
132RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.76778148
133antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.76563348
134histone exchange (GO:0043486)2.74554887
135single strand break repair (GO:0000012)2.72760377
136gene silencing (GO:0016458)2.70760701
137sister chromatid cohesion (GO:0007062)2.69271255
138nucleus organization (GO:0006997)2.69066199
139nuclear pore organization (GO:0006999)2.67919477
140natural killer cell mediated cytotoxicity (GO:0042267)2.67524745
141natural killer cell mediated immunity (GO:0002228)2.67524745
142meiotic chromosome segregation (GO:0045132)2.65539469
143chaperone-mediated protein complex assembly (GO:0051131)2.61861501
144cilium or flagellum-dependent cell motility (GO:0001539)13.1486832
145piRNA metabolic process (GO:0034587)12.1789077
146fusion of sperm to egg plasma membrane (GO:0007342)11.9788067
147sperm motility (GO:0030317)11.3292777
148multicellular organism reproduction (GO:0032504)10.4115176
149acrosome assembly (GO:0001675)10.1521865
150male meiosis (GO:0007140)10.1264129
151sperm-egg recognition (GO:0035036)10.0932291

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.68482308
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.96805884
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.51567604
4EZH2_22144423_ChIP-Seq_EOC_Human4.30600283
5GATA1_22025678_ChIP-Seq_K562_Human3.84569874
6BP1_19119308_ChIP-ChIP_Hs578T_Human3.29899636
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.28652248
8BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.96459852
9FLI1_27457419_Chip-Seq_LIVER_Mouse2.81607695
10STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.70495281
11PCGF2_27294783_Chip-Seq_ESCs_Mouse2.60483279
12SCL_19346495_ChIP-Seq_HPC-7_Human2.41272826
13VDR_22108803_ChIP-Seq_LS180_Human2.37813968
14MYB_26560356_Chip-Seq_TH2_Human2.27969151
15GATA1_26923725_Chip-Seq_HPCs_Mouse2.12471199
16FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.09971914
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.09599065
18VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.07992101
19EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.06760787
20RUNX_20019798_ChIP-Seq_JUKART_Human2.05217980
21PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.99008736
22CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.95363280
23FUS_26573619_Chip-Seq_HEK293_Human1.93963934
24KAP1_22055183_ChIP-Seq_ESCs_Mouse1.93943083
25NFE2_27457419_Chip-Seq_LIVER_Mouse1.91601477
26FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.87835602
27ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.86947514
28SUZ12_27294783_Chip-Seq_NPCs_Mouse1.86239029
29SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.84805929
30PCGF2_27294783_Chip-Seq_NPCs_Mouse1.81916425
31KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.78477003
32STAT1_17558387_ChIP-Seq_HELA_Human1.72296722
33MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.67541108
34ELK4_26923725_Chip-Seq_MESODERM_Mouse1.66878673
35* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.65403113
36CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.65081919
37GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.60608860
38RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.59461044
39TAL1_26923725_Chip-Seq_HPCs_Mouse1.54699860
40TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.53855082
41TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.53440604
42NANOG_20526341_ChIP-Seq_ESCs_Human1.52439384
43ZFP57_27257070_Chip-Seq_ESCs_Mouse1.51975390
44STAT6_21828071_ChIP-Seq_BEAS2B_Human1.51195945
45EZH2_27294783_Chip-Seq_NPCs_Mouse1.51117418
46IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.50686826
47NANOG_18555785_Chip-Seq_ESCs_Mouse1.48299951
48IRF1_19129219_ChIP-ChIP_H3396_Human1.47309673
49TP63_19390658_ChIP-ChIP_HaCaT_Human1.44322227
50KDM2B_26808549_Chip-Seq_REH_Human1.43628649
51ERA_21632823_ChIP-Seq_H3396_Human1.42651977
52RAC3_21632823_ChIP-Seq_H3396_Human1.42107873
53CRX_20693478_ChIP-Seq_RETINA_Mouse1.41119002
54* AUTS2_25519132_ChIP-Seq_293T-REX_Human1.39616074
55GATA3_27048872_Chip-Seq_THYMUS_Human1.39201070
56BCL6_27268052_Chip-Seq_Bcells_Human1.37972197
57EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.36734922
58P53_22387025_ChIP-Seq_ESCs_Mouse1.35513348
59STAT3_18555785_Chip-Seq_ESCs_Mouse1.35500726
60IRF8_21731497_ChIP-ChIP_J774_Mouse1.35078550
61SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.35051685
62OCT4_18555785_Chip-Seq_ESCs_Mouse1.34194480
63FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.33644452
64MYB_26560356_Chip-Seq_TH1_Human1.32427938
65IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.32345413
66CBP_20019798_ChIP-Seq_JUKART_Human1.32345413
67EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.31045387
68EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.30972594
69MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.30926113
70RNF2_27304074_Chip-Seq_NSC_Mouse1.30471871
71EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.29655201
72RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.29561033
73BCOR_27268052_Chip-Seq_Bcells_Human1.29527114
74CBX2_27304074_Chip-Seq_ESCs_Mouse1.28376290
75CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.28082052
76GATA3_26560356_Chip-Seq_TH1_Human1.27664622
77CMYC_18555785_Chip-Seq_ESCs_Mouse1.27357020
78OCT4_21477851_ChIP-Seq_ESCs_Mouse1.27131735
79GATA3_26560356_Chip-Seq_TH2_Human1.26808180
80GATA3_21867929_ChIP-Seq_TH1_Mouse1.26691681
81P300_18555785_Chip-Seq_ESCs_Mouse1.26307285
82PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.26154982
83* FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26067153
84KLF4_18555785_Chip-Seq_ESCs_Mouse1.25691257
85MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25684464
86TAF2_19829295_ChIP-Seq_ESCs_Human1.25604886
87EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.24988999
88MYC_19829295_ChIP-Seq_ESCs_Human1.24778382
89GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.24478142
90YY1_22570637_ChIP-Seq_MALME-3M_Human1.23992440
91OCT4_20526341_ChIP-Seq_ESCs_Human1.23639393
92MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.23337875
93TP53_22573176_ChIP-Seq_HFKS_Human1.23314144
94SUZ12_18555785_Chip-Seq_ESCs_Mouse1.23195643
95WDR5_24793694_ChIP-Seq_LNCAP_Human1.22895664
96RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.21803624
97IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.21699123
98FOXA1_27270436_Chip-Seq_PROSTATE_Human1.21355612
99FOXA1_25329375_ChIP-Seq_VCAP_Human1.21355612
100ESRRB_18555785_Chip-Seq_ESCs_Mouse1.21161824
101SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.19772784
102ETV2_25802403_ChIP-Seq_MESCs_Mouse1.19727170
103FLI1_21867929_ChIP-Seq_TH2_Mouse1.18040862
104RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.17401048
105GATA3_21867929_ChIP-Seq_CD8_Mouse1.16811669
106UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16746922
107NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.16587868
108CTBP2_25329375_ChIP-Seq_LNCAP_Human1.16580576
109E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.15956434
110PU1_27457419_Chip-Seq_LIVER_Mouse1.15134759
111PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.14858878
112E2F1_18555785_Chip-Seq_ESCs_Mouse1.14791728
113POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.13952929
114TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13952929
115CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.13885602
116ZNF274_21170338_ChIP-Seq_K562_Hela1.13782377
117* SMRT_27268052_Chip-Seq_Bcells_Human1.13768906
118GATA3_21878914_ChIP-Seq_MCF-7_Human1.13314933
119VDR_24787735_ChIP-Seq_THP-1_Human1.12922764
120RUNX1_27457419_Chip-Seq_LIVER_Mouse1.12692706
121VDR_23849224_ChIP-Seq_CD4+_Human1.12619975
122SOX2_18555785_Chip-Seq_ESCs_Mouse1.12522771
123PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.11997047
124CTBP1_25329375_ChIP-Seq_LNCAP_Human1.11606509
125GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.11556739
126FOXA1_21572438_ChIP-Seq_LNCaP_Human1.10950487
127SOX2_22085726_ChIP-Seq_NPCs_Mouse1.09916946
128PRDM14_20953172_ChIP-Seq_ESCs_Human1.09657083
129FOXP3_21729870_ChIP-Seq_TREG_Human1.09500443
130GF1_26923725_Chip-Seq_HPCs_Mouse1.09339832
131P300_27268052_Chip-Seq_Bcells_Human1.08862164
132NMYC_18555785_Chip-Seq_ESCs_Mouse1.07756390
133CTCF_18555785_Chip-Seq_ESCs_Mouse1.07629365
134MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.07398436
135POU3F2_20337985_ChIP-ChIP_501MEL_Human1.07252030
136LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.06652588
137ER_23166858_ChIP-Seq_MCF-7_Human1.06089004
138ZFX_18555785_Chip-Seq_ESCs_Mouse1.05965659
139* RUNX1_26923725_Chip-Seq_HPCs_Mouse1.05283494
140PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.05038014
141TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human1.04660275
142SMAD1_18555785_Chip-Seq_ESCs_Mouse1.03835873
143ELF1_20517297_ChIP-Seq_JURKAT_Human1.03794777
144SALL4_22934838_ChIP-ChIP_CD34+_Human1.03566095
145* FOXH1_21741376_ChIP-Seq_EPCs_Human1.03226981
146* CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03144987
147STAT1_20625510_ChIP-Seq_HELA_Human1.03110355
148IGF1R_20145208_ChIP-Seq_DFB_Human1.03028790
149CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.01845700
150TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00792745
151NCOR_22424771_ChIP-Seq_293T_Human1.00439272
152LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.00252255
153UTX_26944678_Chip-Seq_JUKART_Human0.99499025
154RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.99212058
155TCF4_23295773_ChIP-Seq_U87_Human0.98733716
156CEBPB_22108803_ChIP-Seq_LS180_Human0.97393129
157PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.97358192
158SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.97283970
159SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.97147570
160KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.96510889
161* SMAD4_21741376_ChIP-Seq_EPCs_Human0.95663634
162E2F1_20622854_ChIP-Seq_HELA_Human0.95087906
163FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95046973
164NFYB_21822215_ChIP-Seq_K562_Human0.94698686
165SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.94100335
166STAT3_23295773_ChIP-Seq_U87_Human0.93801169
167TAF15_26573619_Chip-Seq_HEK293_Human0.93664571
168SPI1_20517297_ChIP-Seq_HL60_Human0.93110239
169AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.92410519
170TBL1_22424771_ChIP-Seq_293T_Human0.92327172
171ERG_20517297_ChIP-Seq_VCAP_Human0.90389849
172REST_21632747_ChIP-Seq_MESCs_Mouse0.89380363
173CDX2_22108803_ChIP-Seq_LS180_Human0.88301292
174STAT3_18555785_ChIP-Seq_MESCs_Mouse0.88215668
175P300_19829295_ChIP-Seq_ESCs_Human0.87877223
176* SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.87608264
177PHF8_20622854_ChIP-Seq_HELA_Human0.85429329
178VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.85403390
179P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.85350627
180NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.84797916

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation6.21230020
2MP0003698_abnormal_male_reproductive5.68113466
3MP0001929_abnormal_gametogenesis5.51007775
4MP0002210_abnormal_sex_determination4.08204875
5MP0001145_abnormal_male_reproductive3.29087981
6MP0002161_abnormal_fertility/fecundity3.20720687
7MP0000653_abnormal_sex_gland3.04476733
8MP0002653_abnormal_ependyma_morphology2.80915145
9MP0003646_muscle_fatigue2.79905460
10MP0006292_abnormal_olfactory_placode2.19986131
11MP0008057_abnormal_DNA_replication2.17842244
12MP0003763_abnormal_thymus_physiology2.15650868
13MP0000681_abnormal_thyroid_gland2.05964121
14MP0000566_synostosis2.05307901
15MP0005410_abnormal_fertilization13.7984562
16MP0008058_abnormal_DNA_repair1.95124644
17MP0002160_abnormal_reproductive_system1.82841659
18MP0001800_abnormal_humoral_immune1.74259820
19MP0010094_abnormal_chromosome_stability1.72265993
20MP0001873_stomach_inflammation1.66988965
21MP0000465_gastrointestinal_hemorrhage1.64943935
22MP0005623_abnormal_meninges_morphology1.55145081
23MP0005464_abnormal_platelet_physiology1.52898352
24MP0002398_abnormal_bone_marrow1.51270743
25MP0002396_abnormal_hematopoietic_system1.49483245
26MP0005647_abnormal_sex_gland1.43040033
27MP0009333_abnormal_splenocyte_physiolog1.39231471
28MP0005084_abnormal_gallbladder_morpholo1.37278855
29MP0002234_abnormal_pharynx_morphology1.36346851
30MP0005645_abnormal_hypothalamus_physiol1.34711562
31MP0003252_abnormal_bile_duct1.34496211
32MP0002132_abnormal_respiratory_system1.34234802
33MP0002420_abnormal_adaptive_immunity1.33100742
34MP0003786_premature_aging1.32316878
35MP0003183_abnormal_peptide_metabolism1.31183321
36MP0000689_abnormal_spleen_morphology1.28709724
37MP0003121_genomic_imprinting1.28706871
38MP0000015_abnormal_ear_pigmentation1.27682418
39MP0010368_abnormal_lymphatic_system1.25900414
40MP0000569_abnormal_digit_pigmentation1.25489476
41MP0005671_abnormal_response_to1.24636906
42MP0003806_abnormal_nucleotide_metabolis1.23130755
43MP0000716_abnormal_immune_system1.22305279
44MP0008995_early_reproductive_senescence1.21579724
45MP0005075_abnormal_melanosome_morpholog1.16927611
46MP0002722_abnormal_immune_system1.14972445
47MP0005365_abnormal_bile_salt1.13436917
48MP0002282_abnormal_trachea_morphology1.13006080
49MP0001119_abnormal_female_reproductive1.12434523
50MP0008007_abnormal_cellular_replicative1.11657659
51MP0005389_reproductive_system_phenotype1.06786206
52MP0005451_abnormal_body_composition1.06335045
53MP0000678_abnormal_parathyroid_gland1.05480479
54MP0002102_abnormal_ear_morphology1.03799871
55MP0001835_abnormal_antigen_presentation1.03755199
56MP0003950_abnormal_plasma_membrane1.02393119
57MP0009046_muscle_twitch1.01727527
58MP0000703_abnormal_thymus_morphology1.01588677
59MP0005085_abnormal_gallbladder_physiolo1.01178142
60MP0002429_abnormal_blood_cell1.00189728
61MP0005670_abnormal_white_adipose0.99210214
62MP0003699_abnormal_female_reproductive0.96686169
63MP0002019_abnormal_tumor_incidence0.94625234
64MP0001485_abnormal_pinna_reflex0.90555796
65MP0003943_abnormal_hepatobiliary_system0.90102419
66MP0003718_maternal_effect0.87029419
67MP0004233_abnormal_muscle_weight0.86217226
68MP0003866_abnormal_defecation0.84390993
69MP0003303_peritoneal_inflammation0.83704296
70MP0003111_abnormal_nucleus_morphology0.81790125
71MP0009785_altered_susceptibility_to0.81564529
72MP0000631_abnormal_neuroendocrine_gland0.79918334
73MP0001984_abnormal_olfaction0.78602427
74MP0005551_abnormal_eye_electrophysiolog0.73827811
75MP0002254_reproductive_system_inflammat0.73384826
76MP0003878_abnormal_ear_physiology0.72038690
77MP0005377_hearing/vestibular/ear_phenot0.72038690
78MP0003077_abnormal_cell_cycle0.71887931
79MP0008469_abnormal_protein_level0.69477711
80MP0001486_abnormal_startle_reflex0.69182996
81MP0002148_abnormal_hypersensitivity_rea0.69142520
82MP0001765_abnormal_ion_homeostasis0.69071850
83MP0006036_abnormal_mitochondrial_physio0.68951577
84MP0001664_abnormal_digestion0.66440173
85MP0002127_abnormal_cardiovascular_syste0.65895076
86MP0005174_abnormal_tail_pigmentation0.65775604
87MP0003283_abnormal_digestive_organ0.64729801
88MP0000490_abnormal_crypts_of0.64245363
89MP0001188_hyperpigmentation0.62629500
90MP0006082_CNS_inflammation0.61750441
91MP0000427_abnormal_hair_cycle0.60596724
92MP0001986_abnormal_taste_sensitivity0.60251885
93MP0002295_abnormal_pulmonary_circulatio0.60178191
94MP0005397_hematopoietic_system_phenotyp0.59796062
95MP0001545_abnormal_hematopoietic_system0.59796062
96MP0005503_abnormal_tendon_morphology0.58804504
97MP0002405_respiratory_system_inflammati0.57622309
98MP0003879_abnormal_hair_cell0.57380123
99MP0010307_abnormal_tumor_latency0.54235424
100MP0003448_altered_tumor_morphology0.53662094
101MP0003787_abnormal_imprinting0.53021873
102MP0000685_abnormal_immune_system0.52627804
103MP0010386_abnormal_urinary_bladder0.51577604
104MP0002163_abnormal_gland_morphology0.48902825
105MP0002277_abnormal_respiratory_mucosa0.48744567
106MP0003011_delayed_dark_adaptation0.46932171
107MP0001348_abnormal_lacrimal_gland0.46351938
108MP0004808_abnormal_hematopoietic_stem0.45355627
109MP0002138_abnormal_hepatobiliary_system0.43994834
110MP0002419_abnormal_innate_immunity0.43455365
111MP0004510_myositis0.41412979
112MP0005310_abnormal_salivary_gland0.38914621
113MP0000313_abnormal_cell_death0.38781347
114MP0004134_abnormal_chest_morphology0.38638786
115MP0000358_abnormal_cell_content/0.38083321
116MP0003693_abnormal_embryo_hatching0.37162309
117MP0005025_abnormal_response_to0.37007511
118MP0005395_other_phenotype0.36815585
119MP0005646_abnormal_pituitary_gland0.36624430
120MP0005076_abnormal_cell_differentiation0.36118643
121MP0002723_abnormal_immune_serum0.35968037
122MP0002928_abnormal_bile_duct0.34423332
123MP0001851_eye_inflammation0.33993283
124MP0009278_abnormal_bone_marrow0.33506497
125MP0009115_abnormal_fat_cell0.33324421
126MP0004782_abnormal_surfactant_physiolog0.32846700
127MP0001764_abnormal_homeostasis0.32343526
128MP0009697_abnormal_copulation0.31422602
129MP0003936_abnormal_reproductive_system0.31217819
130MP0001346_abnormal_lacrimal_gland0.29653562
131MP0001727_abnormal_embryo_implantation0.29107781
132MP0001790_abnormal_immune_system0.29026280
133MP0005387_immune_system_phenotype0.29026280
134MP0005253_abnormal_eye_physiology0.28577110
135MP0002638_abnormal_pupillary_reflex0.28450212
136MP0002452_abnormal_antigen_presenting0.28023509
137MP0001905_abnormal_dopamine_level0.27814418
138MP0008932_abnormal_embryonic_tissue0.27354436
139MP0008260_abnormal_autophagy0.27297807
140MP0005000_abnormal_immune_tolerance0.26719234
141MP0004019_abnormal_vitamin_homeostasis0.25945112
142MP0001324_abnormal_eye_pigmentation0.25457573
143MP0003436_decreased_susceptibility_to0.25023155
144MP0009764_decreased_sensitivity_to0.24778952
145MP0002876_abnormal_thyroid_physiology0.24293416
146MP0003959_abnormal_lean_body0.21935079
147MP0001819_abnormal_immune_cell0.20676478
148MP0003186_abnormal_redox_activity0.19909355

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.85814392
2Abnormal respiratory motile cilium morphology (HP:0005938)8.07735277
3Abnormal respiratory epithelium morphology (HP:0012253)8.07735277
4Rhinitis (HP:0012384)7.59649032
5Abnormal ciliary motility (HP:0012262)7.07150596
6Hyperventilation (HP:0002883)6.80257184
7Chronic bronchitis (HP:0004469)6.66688539
8Infertility (HP:0000789)6.17072248
9Nasal polyposis (HP:0100582)5.94692712
10Attenuation of retinal blood vessels (HP:0007843)5.07363564
11Abnormality of the nasal mucosa (HP:0000433)4.77253447
12Nephronophthisis (HP:0000090)4.76076446
13Decreased central vision (HP:0007663)4.68554970
14Bronchiectasis (HP:0002110)4.45357663
15Absent rod-and cone-mediated responses on ERG (HP:0007688)4.34358450
16Male infertility (HP:0003251)4.24885009
17Severe visual impairment (HP:0001141)4.23717524
18Bronchitis (HP:0012387)4.19738233
19Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.97556830
20Abnormal rod and cone electroretinograms (HP:0008323)3.93705536
21Methylmalonic aciduria (HP:0012120)3.93108984
22Abnormality of the renal medulla (HP:0100957)3.68147964
23Acute lymphatic leukemia (HP:0006721)3.53856187
24Abnormal spermatogenesis (HP:0008669)3.50365595
25Abnormality of macular pigmentation (HP:0008002)3.41335005
26Asymmetric septal hypertrophy (HP:0001670)3.24640867
27Bony spicule pigmentary retinopathy (HP:0007737)3.23855641
28Abnormality of B cell number (HP:0010975)3.18704974
29Recurrent sinusitis (HP:0011108)3.18058087
30B lymphocytopenia (HP:0010976)3.05901404
31Gonadotropin excess (HP:0000837)3.05742044
32Recurrent otitis media (HP:0000403)3.03853083
33Hypoplasia of the thymus (HP:0000778)3.03276525
34Autoimmune hemolytic anemia (HP:0001890)3.02088728
35Tubular atrophy (HP:0000092)2.96591785
36Spontaneous abortion (HP:0005268)2.91259692
37Tubulointerstitial nephritis (HP:0001970)2.90745323
38Cone-rod dystrophy (HP:0000548)2.88659286
39Azoospermia (HP:0000027)2.88654848
40Abnormality of the lower motor neuron (HP:0002366)2.87017778
41Limb hypertonia (HP:0002509)2.82377300
42Thrombocytosis (HP:0001894)2.78354469
43Molar tooth sign on MRI (HP:0002419)2.76783149
44Abnormality of midbrain morphology (HP:0002418)2.76783149
45Medial flaring of the eyebrow (HP:0010747)2.69542931
46Tubulointerstitial abnormality (HP:0001969)2.66252051
47Recurrent bronchitis (HP:0002837)2.55104696
48Truncal obesity (HP:0001956)2.53685476
49Abnormality of dicarboxylic acid metabolism (HP:0010995)2.48841003
50Dicarboxylic aciduria (HP:0003215)2.48841003
51Impulsivity (HP:0100710)2.47211769
52Unsteady gait (HP:0002317)2.46507897
53Hypoplasia of the capital femoral epiphysis (HP:0003090)2.43071247
54Progressive cerebellar ataxia (HP:0002073)2.41870411
55Macular degeneration (HP:0000608)2.40869011
56Postaxial foot polydactyly (HP:0001830)2.38617238
57Insulin-resistant diabetes mellitus (HP:0000831)2.37341438
58Fibular hypoplasia (HP:0003038)2.34343960
59Upper motor neuron abnormality (HP:0002127)2.30016615
60Acute myeloid leukemia (HP:0004808)2.28221442
61Tubulointerstitial fibrosis (HP:0005576)2.24904925
62Elevated erythrocyte sedimentation rate (HP:0003565)2.24750634
63Amyotrophic lateral sclerosis (HP:0007354)2.24419675
64Gaze-evoked nystagmus (HP:0000640)2.23219538
65Rhabdomyosarcoma (HP:0002859)2.20495171
66Congenital hepatic fibrosis (HP:0002612)2.18148041
67Impaired proprioception (HP:0010831)2.14599256
68Aplasia/Hypoplasia of the earlobes (HP:0009906)2.14400356
69Facial shape deformation (HP:0011334)2.12080288
70Potter facies (HP:0002009)2.12080288
71Abnormality of the anterior horn cell (HP:0006802)2.09240803
72Degeneration of anterior horn cells (HP:0002398)2.09240803
73Stage 5 chronic kidney disease (HP:0003774)2.08309870
74Genetic anticipation (HP:0003743)2.05609318
75Abnormality of T cells (HP:0002843)2.04757976
76Supernumerary spleens (HP:0009799)2.04541877
77Abnormality of the renal cortex (HP:0011035)2.03555926
78Stomatitis (HP:0010280)2.01126579
79Hyperglycinemia (HP:0002154)2.00992450
80Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.0119935
81Dynein arm defect of respiratory motile cilia (HP:0012255)11.7025985
82Absent/shortened dynein arms (HP:0200106)11.7025985
83Hyperkalemia (HP:0002153)1.99408119
84Congenital stationary night blindness (HP:0007642)1.97772322
85Portal hypertension (HP:0001409)1.96455713
86Gonadal dysgenesis (HP:0000133)1.96389850
87Hypoalphalipoproteinemia (HP:0003233)1.96197605
88Panhypogammaglobulinemia (HP:0003139)1.93223819
89J-shaped sella turcica (HP:0002680)1.92096754
90Prostate neoplasm (HP:0100787)1.92062892
91Photophobia (HP:0000613)1.91263248
92Slow saccadic eye movements (HP:0000514)1.89950046
93Amelogenesis imperfecta (HP:0000705)1.88986204
94Hypophosphatemia (HP:0002148)1.88667471
95Abnormality of the prostate (HP:0008775)1.88174453
96Abolished electroretinogram (ERG) (HP:0000550)1.87884374
97Aplasia/Hypoplasia of the thymus (HP:0010515)1.87134366
98Absent epiphyses (HP:0010577)1.86802376
99Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.86802376
100Abnormality of molar morphology (HP:0011070)1.86770368
101Abnormality of molar (HP:0011077)1.86770368
102Progressive microcephaly (HP:0000253)1.86244757
103Optic nerve hypoplasia (HP:0000609)1.86214590
104Resting tremor (HP:0002322)1.85992404
105Abnormality of permanent molar morphology (HP:0011071)1.85831462
106Abnormality of the dental root (HP:0006486)1.85831462
107Taurodontia (HP:0000679)1.85831462
108Median cleft lip (HP:0000161)1.83888374
109Cerebral hemorrhage (HP:0001342)1.83282656
110Absent frontal sinuses (HP:0002688)1.81741476
111Spastic tetraparesis (HP:0001285)1.81083779
112Menstrual irregularities (HP:0000858)1.81046468
113Decreased electroretinogram (ERG) amplitude (HP:0000654)1.80530254
114Oculomotor apraxia (HP:0000657)1.80157152
115Renal dysplasia (HP:0000110)1.78788861
116Abnormality of the hepatic vasculature (HP:0006707)1.78767834
117T lymphocytopenia (HP:0005403)1.77092722
118Recurrent pneumonia (HP:0006532)1.76611991
119Polydipsia (HP:0001959)1.76575200
120Abnormal drinking behavior (HP:0030082)1.76575200
121Abnormality of dentin (HP:0010299)1.75160955
122Short ribs (HP:0000773)1.73230141
123Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.71706763
124Pancreatic fibrosis (HP:0100732)1.70581797
125Abnormality of T cell number (HP:0011839)1.70037579
126Osteomalacia (HP:0002749)1.68999069
127Myositis (HP:0100614)1.68716322
128Prolonged bleeding time (HP:0003010)1.68477938
129Clitoromegaly (HP:0000057)1.68177579
130Prolonged neonatal jaundice (HP:0006579)1.67392471
131Abnormality of the dental pulp (HP:0006479)1.66842318
132Pulmonary fibrosis (HP:0002206)1.66750777
133Postaxial hand polydactyly (HP:0001162)1.66104837
134Chromosomal breakage induced by crosslinking agents (HP:0003221)1.65904316
135Papillary thyroid carcinoma (HP:0002895)1.65609904
136Optic neuritis (HP:0100653)1.64718267
137Retrobulbar optic neuritis (HP:0100654)1.64718267
138Abnormality of T cell physiology (HP:0011840)1.63639249
139Abnormal delayed hypersensitivity skin test (HP:0002963)1.63323782
140Chronic sinusitis (HP:0011109)1.63264335
141Short thorax (HP:0010306)1.61212316
142Microglossia (HP:0000171)1.58636464
143Deformed sella turcica (HP:0002681)1.55621420
144Facial cleft (HP:0002006)1.55541182
145Aplasia/Hypoplasia of the fibula (HP:0006492)1.55446504
146Dyschromatopsia (HP:0007641)1.55378731
147Aplasia/Hypoplasia of the uvula (HP:0010293)1.55176228
148Abnormal biliary tract physiology (HP:0012439)1.54208468
149Bile duct proliferation (HP:0001408)1.54208468
150Cystic liver disease (HP:0006706)1.54128070
151Chromsome breakage (HP:0040012)1.53666953
152Abnormality of renal excretion (HP:0011036)1.50610617
153Breast carcinoma (HP:0003002)1.48519741
154Congenital primary aphakia (HP:0007707)1.48347719
155Nephropathy (HP:0000112)1.47645253
156Ectopic kidney (HP:0000086)1.47185274
157Decreased motor nerve conduction velocity (HP:0003431)1.44656022
158Aplasia/Hypoplasia of the tongue (HP:0010295)1.44335713
159Gait imbalance (HP:0002141)1.44253140
160Sloping forehead (HP:0000340)1.43698489
161Aplasia/Hypoplasia of the lens (HP:0008063)1.42497897
162True hermaphroditism (HP:0010459)1.42392670
163Choroideremia (HP:0001139)1.40645035
164Heterotopia (HP:0002282)1.40393857
165Abnormal gallbladder physiology (HP:0012438)1.40292731
166Cholecystitis (HP:0001082)1.40292731
167Chronic hepatic failure (HP:0100626)1.38472802
168Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.37949672
169Nephroblastoma (Wilms tumor) (HP:0002667)1.37447405
170Pancreatic cysts (HP:0001737)1.35946399
171Hypoplasia of dental enamel (HP:0006297)1.34692241

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.27061956
2PDK48.27061956
3PDK25.73147051
4TAF15.42592242
5TESK14.42923289
6PRKD33.92558388
7NUAK13.68546547
8ICK3.61895485
9CDK193.35489755
10KIT2.75758897
11BRD42.31885696
12PTK2B2.23387160
13MAP4K12.16649660
14STK392.12233009
15NEK21.95097785
16PIK3CG1.93747812
17WNK41.91493955
18PNCK1.72625612
19RIPK41.65877944
20NLK1.64914952
21PLK41.63020341
22TAOK31.60264042
23CDK81.56447934
24INSRR1.55623634
25VRK21.54810368
26CSNK1G11.49486436
27MAP3K111.47930212
28FLT31.43399939
29STK38L1.42370657
30STK31.38239515
31STK381.29981324
32SYK1.27799176
33TTK1.21311246
34KDR1.19710928
35BRAF1.19699029
36MUSK1.18354899
37CDC71.17001289
38SGK21.15037872
39MAP3K71.11470073
40TEC1.08843053
41VRK11.08106200
42ARAF1.04518022
43GRK71.04055502
44BTK1.02414905
45TIE10.98453713
46CSNK1G30.93896714
47PDK10.92844145
48GRK50.92347318
49MAPK70.91507116
50BMPR1B0.90107582
51PINK10.89765464
52FES0.86273602
53WNK10.85527049
54PBK0.84298803
55RPS6KA60.82805826
56ITK0.81260576
57CSNK1G20.81001187
58SGK4940.78861826
59SGK2230.78861826
60MAP3K140.75937385
61CDK90.75159602
62TNK20.74994138
63MAP4K20.74884734
64HIPK20.73627810
65CDK70.73502242
66MST40.73157360
67MAP2K70.71519288
68CHEK20.70851036
69NEK60.70793317
70SGK30.70431319
71BMPR20.70241222
72CDK40.68737450
73CCNB10.66551833
74IRAK10.63615245
75RPS6KC10.63586880
76RPS6KL10.63586880
77AURKA0.60003813
78TYRO30.59510825
79TGFBR20.56501484
80ATR0.55447387
81HCK0.54340937
82DYRK1A0.52987315
83CHEK10.52353224
84PLK10.50433242
85ERBB40.49758883
86PRKG10.48776426
87LCK0.48087886
88GRK60.47738419
89DYRK1B0.46832246
90PIM20.46225477
91KSR20.46216797
92PDPK10.46033336
93MAPK150.45984679
94CAMK10.45466504
95CSNK1A1L0.45435168
96ATM0.45183113
97MAP3K50.45006868
98MAP3K20.44322799
99LYN0.43659543
100RPS6KA40.42957334
101PIM10.41498630
102CDK60.40198174
103PRKCH0.37691785
104DAPK20.35954986
105LATS10.35357795
106MAPKAPK50.35260144
107TXK0.34955079
108PASK0.34588619
109SMG10.33203565
110ZAK0.32738183
111CDK20.31638984
112BRSK20.31088916
113NTRK20.29934532
114PRKAA10.28984709
115PLK20.27975324
116WEE10.27727316
117MAP3K40.26979091
118PAK10.26964833
119IKBKB0.26358165
120YES10.26187024
121CDK120.26165128
122RPS6KB10.25527884
123CHUK0.25398577
124EIF2AK20.25126055
125AKT30.24651355
126DYRK30.23996256
127MAP3K60.23776833
128CASK0.23367701
129LATS20.21184200
130JAK30.21077308
131BCR0.18913098
132FRK0.17775041
133MAP3K130.17364694
134TBK10.16596888
135STK240.15845288
136CAMK1G0.15401863
137IRAK20.14679734
138PLK30.14144087
139TAOK10.12928462
140CDK30.12892371
141RPS6KA10.12334780
142MARK30.12334200
143PRKCQ0.11850466
144MAP2K60.11066360
145SIK30.10874108
146MTOR0.10779599
147MAP3K10.10032543
148EIF2AK10.09884223
149STK40.09192818
150PRKCG0.08328469
151PRPF4B0.07760802
152MELK0.07255680
153MARK20.06425802
154JAK10.06297345
155CSF1R0.06181557
156IKBKE0.05525519
157MOS0.05414880
158PKN10.05084194
159CSNK2A10.04446913
160RAF10.04277950
161MAP3K90.04028981

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.41463899
2Basal transcription factors_Homo sapiens_hsa030223.59323530
3Fanconi anemia pathway_Homo sapiens_hsa034603.45442187
4Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.07281641
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.96641787
6Dorso-ventral axis formation_Homo sapiens_hsa043202.96173077
7Base excision repair_Homo sapiens_hsa034102.93148932
8Linoleic acid metabolism_Homo sapiens_hsa005912.90436987
9Pyruvate metabolism_Homo sapiens_hsa006202.90408003
10Fatty acid biosynthesis_Homo sapiens_hsa000612.70847928
11Olfactory transduction_Homo sapiens_hsa047402.44255857
12Primary immunodeficiency_Homo sapiens_hsa053402.21296123
13Glucagon signaling pathway_Homo sapiens_hsa049222.15256952
14Mismatch repair_Homo sapiens_hsa034302.08152792
15Pentose phosphate pathway_Homo sapiens_hsa000302.01159448
16Oocyte meiosis_Homo sapiens_hsa041141.87571695
17Ether lipid metabolism_Homo sapiens_hsa005651.84344642
18Nucleotide excision repair_Homo sapiens_hsa034201.83610488
19Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.79474381
20Propanoate metabolism_Homo sapiens_hsa006401.75284412
21SNARE interactions in vesicular transport_Homo sapiens_hsa041301.71020444
22Graft-versus-host disease_Homo sapiens_hsa053321.60243469
23Glycosaminoglycan degradation_Homo sapiens_hsa005311.58589311
24Collecting duct acid secretion_Homo sapiens_hsa049661.56277597
25Legionellosis_Homo sapiens_hsa051341.52868151
26DNA replication_Homo sapiens_hsa030301.49374238
27Homologous recombination_Homo sapiens_hsa034401.41961698
28Huntingtons disease_Homo sapiens_hsa050161.40623924
29Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.36869232
30Cysteine and methionine metabolism_Homo sapiens_hsa002701.35172383
31RNA polymerase_Homo sapiens_hsa030201.28319182
32Glycerolipid metabolism_Homo sapiens_hsa005611.28230428
33Hematopoietic cell lineage_Homo sapiens_hsa046401.27264831
34RNA degradation_Homo sapiens_hsa030181.25965585
35Rheumatoid arthritis_Homo sapiens_hsa053231.25781174
36Antigen processing and presentation_Homo sapiens_hsa046121.25020871
37T cell receptor signaling pathway_Homo sapiens_hsa046601.24936116
38Glycerophospholipid metabolism_Homo sapiens_hsa005641.22260617
39mRNA surveillance pathway_Homo sapiens_hsa030151.21573588
40Selenocompound metabolism_Homo sapiens_hsa004501.20680988
41Influenza A_Homo sapiens_hsa051641.20549471
42Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.18082418
43Transcriptional misregulation in cancer_Homo sapiens_hsa052021.15942403
44Maturity onset diabetes of the young_Homo sapiens_hsa049501.15047346
45RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.14970608
46Pyrimidine metabolism_Homo sapiens_hsa002401.12843509
47Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.09817387
48Carbohydrate digestion and absorption_Homo sapiens_hsa049731.08162935
49Arachidonic acid metabolism_Homo sapiens_hsa005901.08088565
50NOD-like receptor signaling pathway_Homo sapiens_hsa046211.07788016
51Allograft rejection_Homo sapiens_hsa053301.07591552
52Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.05636554
53RNA transport_Homo sapiens_hsa030131.04940401
54Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.03844508
55Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.02734804
56Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.02714738
57Viral myocarditis_Homo sapiens_hsa054161.01512771
58Measles_Homo sapiens_hsa051621.00944717
59Ribosome_Homo sapiens_hsa030100.99838729
60Mineral absorption_Homo sapiens_hsa049780.99202911
61Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.98531830
62Acute myeloid leukemia_Homo sapiens_hsa052210.94975301
63Regulation of autophagy_Homo sapiens_hsa041400.93322242
64Salmonella infection_Homo sapiens_hsa051320.93150089
65Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.91502850
66Cell cycle_Homo sapiens_hsa041100.90784445
67Amphetamine addiction_Homo sapiens_hsa050310.90757656
68PPAR signaling pathway_Homo sapiens_hsa033200.86848899
69Purine metabolism_Homo sapiens_hsa002300.86457293
70Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.85678344
71Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.83876521
72Phototransduction_Homo sapiens_hsa047440.82065805
73Toxoplasmosis_Homo sapiens_hsa051450.81860882
74Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.78102675
75Malaria_Homo sapiens_hsa051440.75779740
76Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.75751977
77Asthma_Homo sapiens_hsa053100.75104331
78Herpes simplex infection_Homo sapiens_hsa051680.72536167
79ABC transporters_Homo sapiens_hsa020100.72519589
80Type I diabetes mellitus_Homo sapiens_hsa049400.71624854
81Platelet activation_Homo sapiens_hsa046110.69878257
82Phagosome_Homo sapiens_hsa041450.67837782
83Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.65825666
84Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.65573684
85Sphingolipid metabolism_Homo sapiens_hsa006000.63886243
86Renin secretion_Homo sapiens_hsa049240.63841161
87TNF signaling pathway_Homo sapiens_hsa046680.63615927
88Taste transduction_Homo sapiens_hsa047420.63125050
89Non-homologous end-joining_Homo sapiens_hsa034500.62985234
90Ovarian steroidogenesis_Homo sapiens_hsa049130.62760469
91Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61973679
92Autoimmune thyroid disease_Homo sapiens_hsa053200.60798660
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.60705431
94Steroid hormone biosynthesis_Homo sapiens_hsa001400.57902030
95Adipocytokine signaling pathway_Homo sapiens_hsa049200.57390044
96p53 signaling pathway_Homo sapiens_hsa041150.56417927
97Fructose and mannose metabolism_Homo sapiens_hsa000510.56235660
98Osteoclast differentiation_Homo sapiens_hsa043800.55926286
99Sphingolipid signaling pathway_Homo sapiens_hsa040710.54635327
100Peroxisome_Homo sapiens_hsa041460.51026668
101Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.48406737
102One carbon pool by folate_Homo sapiens_hsa006700.47409400
103Intestinal immune network for IgA production_Homo sapiens_hsa046720.47002905
104Carbon metabolism_Homo sapiens_hsa012000.46683084
105Epstein-Barr virus infection_Homo sapiens_hsa051690.46410407
106Glutathione metabolism_Homo sapiens_hsa004800.45888205
107MAPK signaling pathway_Homo sapiens_hsa040100.45123052
108Toll-like receptor signaling pathway_Homo sapiens_hsa046200.45103100
109Phosphatidylinositol signaling system_Homo sapiens_hsa040700.44847202
110Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.44224320
111Butanoate metabolism_Homo sapiens_hsa006500.43417462
112African trypanosomiasis_Homo sapiens_hsa051430.42371855
113Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.42095922
114Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.42069802
115VEGF signaling pathway_Homo sapiens_hsa043700.41901427
116Inositol phosphate metabolism_Homo sapiens_hsa005620.41617914
117B cell receptor signaling pathway_Homo sapiens_hsa046620.41255924
118Staphylococcus aureus infection_Homo sapiens_hsa051500.40588348
119Hepatitis B_Homo sapiens_hsa051610.40314612
120Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.39781523
121Vascular smooth muscle contraction_Homo sapiens_hsa042700.39137360
122Longevity regulating pathway - mammal_Homo sapiens_hsa042110.38746041
123Tuberculosis_Homo sapiens_hsa051520.38346902
124mTOR signaling pathway_Homo sapiens_hsa041500.37066786
125Jak-STAT signaling pathway_Homo sapiens_hsa046300.35721466
126Leishmaniasis_Homo sapiens_hsa051400.35264302
127Chemokine signaling pathway_Homo sapiens_hsa040620.34542248
128Long-term potentiation_Homo sapiens_hsa047200.32867558
129Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.31522485
130Estrogen signaling pathway_Homo sapiens_hsa049150.30927053
131Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.29354801
132Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.29058593
133Viral carcinogenesis_Homo sapiens_hsa052030.28536616
134Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.28451514
135Synaptic vesicle cycle_Homo sapiens_hsa047210.27114971
136Fatty acid metabolism_Homo sapiens_hsa012120.26936307
137Fatty acid degradation_Homo sapiens_hsa000710.26634375
138HTLV-I infection_Homo sapiens_hsa051660.26602174
139Fat digestion and absorption_Homo sapiens_hsa049750.26551053
140Proteasome_Homo sapiens_hsa030500.25727778
141Steroid biosynthesis_Homo sapiens_hsa001000.25661360
142Calcium signaling pathway_Homo sapiens_hsa040200.25439757
143Endocytosis_Homo sapiens_hsa041440.24793390
144Vitamin digestion and absorption_Homo sapiens_hsa049770.22355502
145Cardiac muscle contraction_Homo sapiens_hsa042600.22295038
146cGMP-PKG signaling pathway_Homo sapiens_hsa040220.22175602
147Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.21321331

Most similar genes based on co-expression Upload to Enrichr

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