

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of inclusion body assembly (GO:0090083) | 8.96883143 |
| 2 | * protein refolding (GO:0042026) | 8.08615403 |
| 3 | cellular response to arsenic-containing substance (GO:0071243) | 5.01340135 |
| 4 | positive regulation by symbiont of host defense response (GO:0052509) | 4.86454479 |
| 5 | modulation by symbiont of host defense response (GO:0052031) | 4.86454479 |
| 6 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.86454479 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.86454479 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.86454479 |
| 9 | modulation by symbiont of host immune response (GO:0052553) | 4.86454479 |
| 10 | negative regulation of striated muscle cell apoptotic process (GO:0010664) | 4.82299049 |
| 11 | negative regulation of cell killing (GO:0031342) | 4.81756540 |
| 12 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.81756540 |
| 13 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.72351491 |
| 14 | regulation of MHC class I biosynthetic process (GO:0045343) | 4.40659652 |
| 15 | macrophage activation involved in immune response (GO:0002281) | 4.38895193 |
| 16 | neutrophil activation involved in immune response (GO:0002283) | 4.35476138 |
| 17 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.25388789 |
| 18 | detection of molecule of bacterial origin (GO:0032490) | 4.18531674 |
| 19 | detection of other organism (GO:0098543) | 4.12357505 |
| 20 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.09768513 |
| 21 | response to peptidoglycan (GO:0032494) | 4.08984444 |
| 22 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.00561395 |
| 23 | detection of bacterium (GO:0016045) | 3.94605674 |
| 24 | microglial cell activation (GO:0001774) | 3.92557489 |
| 25 | detection of external biotic stimulus (GO:0098581) | 3.86148366 |
| 26 | negative regulation of interleukin-12 production (GO:0032695) | 3.83940810 |
| 27 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.83499487 |
| 28 | macrophage activation (GO:0042116) | 3.83336128 |
| 29 | leukocyte aggregation (GO:0070486) | 3.64280288 |
| 30 | neutrophil mediated immunity (GO:0002446) | 3.51531929 |
| 31 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.48821830 |
| 32 | response to host immune response (GO:0052572) | 3.48821830 |
| 33 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.45323335 |
| 34 | neutrophil activation (GO:0042119) | 3.45115270 |
| 35 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.43811492 |
| 36 | viral protein processing (GO:0019082) | 3.43320720 |
| 37 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.43271785 |
| 38 | cellular extravasation (GO:0045123) | 3.42015184 |
| 39 | regulation of mast cell degranulation (GO:0043304) | 3.40609542 |
| 40 | germinal center formation (GO:0002467) | 3.40348694 |
| 41 | positive regulation of ATP catabolic process (GO:1903291) | 3.34808211 |
| 42 | positive regulation of ATPase activity (GO:0032781) | 3.34808211 |
| 43 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.34462729 |
| 44 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 3.34078324 |
| 45 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.33388356 |
| 46 | detection of biotic stimulus (GO:0009595) | 3.32117300 |
| 47 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.29250974 |
| 48 | respiratory burst (GO:0045730) | 3.27602195 |
| 49 | regulation of superoxide anion generation (GO:0032928) | 3.26137135 |
| 50 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.24950327 |
| 51 | granulocyte activation (GO:0036230) | 3.24701061 |
| 52 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.23592493 |
| 53 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.16173957 |
| 54 | cellular response to type I interferon (GO:0071357) | 3.16006163 |
| 55 | type I interferon signaling pathway (GO:0060337) | 3.16006163 |
| 56 | immunoglobulin mediated immune response (GO:0016064) | 3.15571897 |
| 57 | response to type I interferon (GO:0034340) | 3.12819602 |
| 58 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.11935924 |
| 59 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.11935924 |
| 60 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.11922328 |
| 61 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.09979996 |
| 62 | response to host (GO:0075136) | 3.06742214 |
| 63 | response to host defenses (GO:0052200) | 3.06742214 |
| 64 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.06742214 |
| 65 | regulation of striated muscle cell apoptotic process (GO:0010662) | 3.06646424 |
| 66 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.03163424 |
| 67 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.01088388 |
| 68 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.96637722 |
| 69 | myeloid cell activation involved in immune response (GO:0002275) | 2.95117927 |
| 70 | negative regulation of muscle cell apoptotic process (GO:0010656) | 2.93911195 |
| 71 | purine nucleotide salvage (GO:0032261) | 2.93311303 |
| 72 | response to muramyl dipeptide (GO:0032495) | 2.93246888 |
| 73 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.93030324 |
| 74 | myeloid leukocyte mediated immunity (GO:0002444) | 2.91971477 |
| 75 | regulation of leukocyte degranulation (GO:0043300) | 2.91259992 |
| 76 | chaperone-mediated protein folding (GO:0061077) | 2.86657339 |
| 77 | regulation of mast cell activation (GO:0033003) | 2.86466303 |
| 78 | extrinsic apoptotic signaling pathway via death domain receptors (GO:0008625) | 2.85144835 |
| 79 | regulation of gamma-delta T cell activation (GO:0046643) | 2.84122686 |
| 80 | negative regulation of T cell mediated immunity (GO:0002710) | 2.83723143 |
| 81 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.81365997 |
| 82 | defense response to protozoan (GO:0042832) | 2.78823945 |
| 83 | positive regulation of interferon-alpha production (GO:0032727) | 2.77978114 |
| 84 | response to interleukin-15 (GO:0070672) | 2.77812354 |
| 85 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.77626661 |
| 86 | regulation of interferon-alpha production (GO:0032647) | 2.75861133 |
| 87 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.75394749 |
| 88 | negative regulation of interleukin-6 production (GO:0032715) | 2.74535531 |
| 89 | de novo posttranslational protein folding (GO:0051084) | 2.73090381 |
| 90 | B cell mediated immunity (GO:0019724) | 2.72051304 |
| 91 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.71589780 |
| 92 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.68456334 |
| 93 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.68456334 |
| 94 | negative regulation of glycoprotein metabolic process (GO:1903019) | 2.67653988 |
| 95 | positive regulation of mast cell activation (GO:0033005) | 2.67483462 |
| 96 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.63086637 |
| 97 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.59812665 |
| 98 | cellular response to interleukin-15 (GO:0071350) | 2.57454834 |
| 99 | negative regulation of inclusion body assembly (GO:0090084) | 14.7879230 |
| 100 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 14.3300396 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.73816228 |
| 2 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.53684013 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.47829632 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.02796322 |
| 5 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.12609255 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.03353023 |
| 7 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.83654280 |
| 8 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.79464083 |
| 9 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.76035694 |
| 10 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.70059489 |
| 11 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.67407920 |
| 12 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.66905707 |
| 13 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.57247929 |
| 14 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.50780332 |
| 15 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.34606166 |
| 16 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.33808001 |
| 17 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.32438747 |
| 18 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.32284605 |
| 19 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 2.29080583 |
| 20 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.24206329 |
| 21 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.24033776 |
| 22 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.22792875 |
| 23 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.14590996 |
| 24 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.07108310 |
| 25 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.06621372 |
| 26 | MAF_26560356_Chip-Seq_TH1_Human | 2.00399132 |
| 27 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.97971625 |
| 28 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.91898727 |
| 29 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.91519022 |
| 30 | SPI1_23127762_ChIP-Seq_K562_Human | 1.90359047 |
| 31 | MYB_26560356_Chip-Seq_TH1_Human | 1.86105952 |
| 32 | * MYB_26560356_Chip-Seq_TH2_Human | 1.84802673 |
| 33 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.79713158 |
| 34 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.78857449 |
| 35 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.77815740 |
| 36 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.77245918 |
| 37 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.67968805 |
| 38 | * ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.66443875 |
| 39 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.66271991 |
| 40 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.66266317 |
| 41 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.65782822 |
| 42 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.57794277 |
| 43 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.57611177 |
| 44 | MAF_26560356_Chip-Seq_TH2_Human | 1.56547280 |
| 45 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.53036609 |
| 46 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.52237826 |
| 47 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.52083650 |
| 48 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.51853002 |
| 49 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.51116826 |
| 50 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.42686102 |
| 51 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.36955899 |
| 52 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.36892445 |
| 53 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.33277615 |
| 54 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.30867983 |
| 55 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.29391064 |
| 56 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.27769977 |
| 57 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.27136369 |
| 58 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.25743602 |
| 59 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.23816237 |
| 60 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.23729188 |
| 61 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.22830973 |
| 62 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.22023002 |
| 63 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.21220517 |
| 64 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.20104935 |
| 65 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.19714503 |
| 66 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.18551649 |
| 67 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.16147418 |
| 68 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.16032170 |
| 69 | * GATA3_26560356_Chip-Seq_TH2_Human | 1.15452882 |
| 70 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.13822070 |
| 71 | MYC_22102868_ChIP-Seq_BL_Human | 1.12531659 |
| 72 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.11851429 |
| 73 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.11506171 |
| 74 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.11366751 |
| 75 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.11149306 |
| 76 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.08659001 |
| 77 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.03538783 |
| 78 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03180302 |
| 79 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.01722308 |
| 80 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.01372066 |
| 81 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.00230547 |
| 82 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.99503495 |
| 83 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.99125989 |
| 84 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.97819028 |
| 85 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.97579791 |
| 86 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97428658 |
| 87 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.92682333 |
| 88 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.91112137 |
| 89 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89278420 |
| 90 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.88460453 |
| 91 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88096508 |
| 92 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.88009746 |
| 93 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.87511229 |
| 94 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.86538794 |
| 95 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.86188552 |
| 96 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.84135993 |
| 97 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.83468574 |
| 98 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.82500359 |
| 99 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.81270016 |
| 100 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.79196539 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003828_pulmonary_edema | 5.04578371 |
| 2 | MP0003806_abnormal_nucleotide_metabolis | 4.59194151 |
| 3 | MP0003724_increased_susceptibility_to | 4.55824166 |
| 4 | MP0003436_decreased_susceptibility_to | 3.97033487 |
| 5 | MP0003303_peritoneal_inflammation | 3.52959920 |
| 6 | MP0002132_abnormal_respiratory_system | 3.17630480 |
| 7 | MP0003221_abnormal_cardiomyocyte_apopto | 3.16072307 |
| 8 | MP0001835_abnormal_antigen_presentation | 2.94723781 |
| 9 | MP0009785_altered_susceptibility_to | 2.88260209 |
| 10 | MP0002419_abnormal_innate_immunity | 2.73946688 |
| 11 | MP0006082_CNS_inflammation | 2.58682017 |
| 12 | MP0005025_abnormal_response_to | 2.56105000 |
| 13 | MP0005000_abnormal_immune_tolerance | 2.52398490 |
| 14 | MP0001800_abnormal_humoral_immune | 2.50240140 |
| 15 | MP0000749_muscle_degeneration | 2.48068054 |
| 16 | MP0005387_immune_system_phenotype | 2.46953313 |
| 17 | MP0001790_abnormal_immune_system | 2.46953313 |
| 18 | MP0005671_abnormal_response_to | 2.42096833 |
| 19 | MP0002723_abnormal_immune_serum | 2.28155061 |
| 20 | MP0003300_gastrointestinal_ulcer | 2.22872111 |
| 21 | MP0002148_abnormal_hypersensitivity_rea | 2.20311856 |
| 22 | MP0000685_abnormal_immune_system | 2.17426084 |
| 23 | MP0002452_abnormal_antigen_presenting | 2.15901574 |
| 24 | MP0000343_altered_response_to | 2.15418878 |
| 25 | MP0008260_abnormal_autophagy | 2.09865173 |
| 26 | MP0002420_abnormal_adaptive_immunity | 2.06826239 |
| 27 | MP0001819_abnormal_immune_cell | 2.04328839 |
| 28 | MP0001533_abnormal_skeleton_physiology | 1.91469683 |
| 29 | MP0002653_abnormal_ependyma_morphology | 1.81587394 |
| 30 | MP0003172_abnormal_lysosome_physiology | 1.71664860 |
| 31 | MP0003075_altered_response_to | 1.71509132 |
| 32 | MP0002405_respiratory_system_inflammati | 1.70857039 |
| 33 | MP0002277_abnormal_respiratory_mucosa | 1.63585503 |
| 34 | MP0005451_abnormal_body_composition | 1.61184180 |
| 35 | MP0000716_abnormal_immune_system | 1.60378768 |
| 36 | MP0005058_abnormal_lysosome_morphology | 1.59179531 |
| 37 | MP0001845_abnormal_inflammatory_respons | 1.55175700 |
| 38 | MP0009840_abnormal_foam_cell | 1.43167657 |
| 39 | MP0004947_skin_inflammation | 1.42271946 |
| 40 | MP0003763_abnormal_thymus_physiology | 1.36955499 |
| 41 | MP0002398_abnormal_bone_marrow | 1.36182656 |
| 42 | MP0000689_abnormal_spleen_morphology | 1.33260520 |
| 43 | MP0002722_abnormal_immune_system | 1.33078290 |
| 44 | MP0009764_decreased_sensitivity_to | 1.32536394 |
| 45 | MP0008469_abnormal_protein_level | 1.32332281 |
| 46 | MP0003191_abnormal_cellular_cholesterol | 1.31782393 |
| 47 | MP0010155_abnormal_intestine_physiology | 1.30772242 |
| 48 | MP0000703_abnormal_thymus_morphology | 1.29613997 |
| 49 | MP0002429_abnormal_blood_cell | 1.24269865 |
| 50 | MP0004510_myositis | 1.23950127 |
| 51 | MP0005164_abnormal_response_to | 1.23802941 |
| 52 | MP0004883_abnormal_blood_vessel | 1.22840337 |
| 53 | MP0005464_abnormal_platelet_physiology | 1.21081110 |
| 54 | MP0009333_abnormal_splenocyte_physiolog | 1.18744632 |
| 55 | MP0003690_abnormal_glial_cell | 1.16954877 |
| 56 | MP0000465_gastrointestinal_hemorrhage | 1.16578145 |
| 57 | MP0002332_abnormal_exercise_endurance | 1.09048869 |
| 58 | MP0009278_abnormal_bone_marrow | 1.05431485 |
| 59 | MP0005334_abnormal_fat_pad | 0.99807742 |
| 60 | MP0009763_increased_sensitivity_to | 0.96572566 |
| 61 | MP0005166_decreased_susceptibility_to | 0.95962229 |
| 62 | MP0003866_abnormal_defecation | 0.95797400 |
| 63 | MP0008004_abnormal_stomach_pH | 0.95181904 |
| 64 | MP0002133_abnormal_respiratory_system | 0.95015373 |
| 65 | MP0005388_respiratory_system_phenotype | 0.95015373 |
| 66 | MP0001851_eye_inflammation | 0.93547026 |
| 67 | MP0005535_abnormal_body_temperature | 0.93283147 |
| 68 | MP0002998_abnormal_bone_remodeling | 0.92547832 |
| 69 | MP0005310_abnormal_salivary_gland | 0.89436163 |
| 70 | MP0000604_amyloidosis | 0.88415364 |
| 71 | MP0003656_abnormal_erythrocyte_physiolo | 0.83232819 |
| 72 | MP0003453_abnormal_keratinocyte_physiol | 0.80421075 |
| 73 | MP0004381_abnormal_hair_follicle | 0.79015686 |
| 74 | MP0003329_amyloid_beta_deposits | 0.78491656 |
| 75 | MP0005390_skeleton_phenotype | 0.76526402 |
| 76 | MP0002970_abnormal_white_adipose | 0.71206807 |
| 77 | MP0002396_abnormal_hematopoietic_system | 0.71201624 |
| 78 | MP0001663_abnormal_digestive_system | 0.70112950 |
| 79 | MP0001764_abnormal_homeostasis | 0.70045805 |
| 80 | MP0003183_abnormal_peptide_metabolism | 0.68306779 |
| 81 | MP0000858_altered_metastatic_potential | 0.66253564 |
| 82 | MP0000015_abnormal_ear_pigmentation | 0.65971311 |
| 83 | MP0003448_altered_tumor_morphology | 0.64356262 |
| 84 | MP0001853_heart_inflammation | 0.62166490 |
| 85 | MP0005397_hematopoietic_system_phenotyp | 0.61917192 |
| 86 | MP0001545_abnormal_hematopoietic_system | 0.61917192 |
| 87 | MP0008007_abnormal_cellular_replicative | 0.60953302 |
| 88 | MP0009765_abnormal_xenobiotic_induced | 0.59128640 |
| 89 | MP0005376_homeostasis/metabolism_phenot | 0.56276567 |
| 90 | MP0002928_abnormal_bile_duct | 0.56149728 |
| 91 | MP0000249_abnormal_blood_vessel | 0.55358358 |
| 92 | MP0005075_abnormal_melanosome_morpholog | 0.55156139 |
| 93 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.54073723 |
| 94 | MP0003795_abnormal_bone_structure | 0.54005186 |
| 95 | MP0001873_stomach_inflammation | 0.52959848 |
| 96 | MP0004142_abnormal_muscle_tone | 0.52845625 |
| 97 | MP0005319_abnormal_enzyme/_coenzyme | 0.49981869 |
| 98 | MP0008873_increased_physiological_sensi | 0.47879450 |
| 99 | MP0002693_abnormal_pancreas_physiology | 0.47271932 |
| 100 | MP0001727_abnormal_embryo_implantation | 0.46935197 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Diaphragmatic weakness (HP:0009113) | 8.91532610 |
| 2 | Easy fatigability (HP:0003388) | 5.22406465 |
| 3 | Eczematoid dermatitis (HP:0000976) | 5.01120237 |
| 4 | Orchitis (HP:0100796) | 4.86756269 |
| 5 | Myositis (HP:0100614) | 4.81102744 |
| 6 | Abnormality of macrophages (HP:0004311) | 4.79353073 |
| 7 | Recurrent bacterial skin infections (HP:0005406) | 4.74527439 |
| 8 | Optic neuritis (HP:0100653) | 4.73731542 |
| 9 | Retrobulbar optic neuritis (HP:0100654) | 4.73731542 |
| 10 | Recurrent abscess formation (HP:0002722) | 4.61972816 |
| 11 | Stomatitis (HP:0010280) | 3.79142703 |
| 12 | Episodic fever (HP:0001954) | 3.73080567 |
| 13 | Mediastinal lymphadenopathy (HP:0100721) | 3.67996987 |
| 14 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.58376093 |
| 15 | Spinal rigidity (HP:0003306) | 3.53168489 |
| 16 | Acute hepatic failure (HP:0006554) | 3.36432780 |
| 17 | Keratoconjunctivitis sicca (HP:0001097) | 3.34157382 |
| 18 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.26656912 |
| 19 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.21246693 |
| 20 | Nuclear cataract (HP:0100018) | 3.20577292 |
| 21 | Recurrent skin infections (HP:0001581) | 3.16808892 |
| 22 | Encephalitis (HP:0002383) | 3.15970156 |
| 23 | Chronic obstructive pulmonary disease (HP:0006510) | 3.15647156 |
| 24 | Obstructive lung disease (HP:0006536) | 3.15647156 |
| 25 | Meningitis (HP:0001287) | 3.14882705 |
| 26 | Muscle fiber splitting (HP:0003555) | 3.10404128 |
| 27 | Gastrointestinal infarctions (HP:0005244) | 3.09931874 |
| 28 | Recurrent fungal infections (HP:0002841) | 3.08056294 |
| 29 | Keratoconjunctivitis (HP:0001096) | 3.05307040 |
| 30 | Rapidly progressive (HP:0003678) | 3.00187264 |
| 31 | Nasal speech (HP:0001611) | 2.90353157 |
| 32 | Generalized amyotrophy (HP:0003700) | 2.90352464 |
| 33 | Inflammation of the large intestine (HP:0002037) | 2.90260878 |
| 34 | Abnormality of glycolipid metabolism (HP:0010969) | 2.88757753 |
| 35 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.88757753 |
| 36 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.88757753 |
| 37 | Abnormality of the peritoneum (HP:0002585) | 2.88219088 |
| 38 | EMG: myopathic abnormalities (HP:0003458) | 2.87258156 |
| 39 | Muscular dystrophy (HP:0003560) | 2.85440813 |
| 40 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.80655356 |
| 41 | Recurrent cutaneous fungal infections (HP:0011370) | 2.80655356 |
| 42 | Gastrointestinal inflammation (HP:0004386) | 2.74740614 |
| 43 | Urticaria (HP:0001025) | 2.69410063 |
| 44 | Increased IgE level (HP:0003212) | 2.67706711 |
| 45 | Anorexia (HP:0002039) | 2.66722024 |
| 46 | Vasculitis (HP:0002633) | 2.53168646 |
| 47 | Spontaneous hematomas (HP:0007420) | 2.47922827 |
| 48 | Loss of speech (HP:0002371) | 2.42762654 |
| 49 | Glomerulonephritis (HP:0000099) | 2.41993348 |
| 50 | Hemoptysis (HP:0002105) | 2.40854456 |
| 51 | Pulmonary infiltrates (HP:0002113) | 2.39816566 |
| 52 | Abnormality of the pleura (HP:0002103) | 2.35731748 |
| 53 | Gingivitis (HP:0000230) | 2.32288231 |
| 54 | Hypochromic microcytic anemia (HP:0004840) | 2.31018015 |
| 55 | Acute necrotizing encephalopathy (HP:0006965) | 2.30117540 |
| 56 | Split foot (HP:0001839) | 2.29627327 |
| 57 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.29058010 |
| 58 | Disinhibition (HP:0000734) | 2.27053895 |
| 59 | Hypochromic anemia (HP:0001931) | 2.25738112 |
| 60 | Glomerulopathy (HP:0100820) | 2.23585731 |
| 61 | Parakeratosis (HP:0001036) | 2.21060697 |
| 62 | Arthropathy (HP:0003040) | 2.19107722 |
| 63 | Systemic lupus erythematosus (HP:0002725) | 2.18700385 |
| 64 | Knee flexion contracture (HP:0006380) | 2.17972354 |
| 65 | Colitis (HP:0002583) | 2.16307595 |
| 66 | Difficulty climbing stairs (HP:0003551) | 2.15892703 |
| 67 | Petechiae (HP:0000967) | 2.10145444 |
| 68 | Pulmonary embolism (HP:0002204) | 2.06965676 |
| 69 | Prolonged bleeding time (HP:0003010) | 2.06904373 |
| 70 | Panhypogammaglobulinemia (HP:0003139) | 2.06800652 |
| 71 | Gangrene (HP:0100758) | 2.03211167 |
| 72 | Mutism (HP:0002300) | 2.01271187 |
| 73 | Progressive macrocephaly (HP:0004481) | 2.00290500 |
| 74 | Axonal loss (HP:0003447) | 10.2003151 |
| 75 | Lymphopenia (HP:0001888) | 1.97582684 |
| 76 | Cellulitis (HP:0100658) | 1.95307127 |
| 77 | Severe visual impairment (HP:0001141) | 1.94267739 |
| 78 | Abnormality of T cell physiology (HP:0011840) | 1.92244431 |
| 79 | Cerebral edema (HP:0002181) | 1.89938378 |
| 80 | Polyneuropathy (HP:0001271) | 1.89044701 |
| 81 | Hepatosplenomegaly (HP:0001433) | 1.88827902 |
| 82 | Interstitial pulmonary disease (HP:0006530) | 1.88023965 |
| 83 | Peritonitis (HP:0002586) | 1.87328256 |
| 84 | Abnormality of T cells (HP:0002843) | 1.86479680 |
| 85 | Vacuolated lymphocytes (HP:0001922) | 1.85480751 |
| 86 | Leukocytosis (HP:0001974) | 1.84718758 |
| 87 | Recurrent viral infections (HP:0004429) | 1.84530981 |
| 88 | Amyloidosis (HP:0011034) | 1.83050094 |
| 89 | Aseptic necrosis (HP:0010885) | 1.81209652 |
| 90 | Microcytic anemia (HP:0001935) | 1.81104850 |
| 91 | Gingival bleeding (HP:0000225) | 1.80087860 |
| 92 | Chest pain (HP:0100749) | 1.79362155 |
| 93 | Epistaxis (HP:0000421) | 1.78045141 |
| 94 | Dysostosis multiplex (HP:0000943) | 1.77424375 |
| 95 | Vertigo (HP:0002321) | 1.75546700 |
| 96 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.75376109 |
| 97 | Arterial thrombosis (HP:0004420) | 1.73439864 |
| 98 | Increased IgM level (HP:0003496) | 1.72453917 |
| 99 | Pustule (HP:0200039) | 1.70387266 |
| 100 | Increased serum ferritin (HP:0003281) | 1.68489735 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAPKAPK5 | 9.72076886 |
| 2 | BCKDK | 4.24007751 |
| 3 | TSSK6 | 3.37560546 |
| 4 | RIPK4 | 2.88813751 |
| 5 | ERN1 | 2.72281629 |
| 6 | MAP4K1 | 2.33772215 |
| 7 | BLK | 2.27330423 |
| 8 | MAP2K3 | 2.27227343 |
| 9 | IRAK4 | 2.26055303 |
| 10 | TNK2 | 1.89261174 |
| 11 | FES | 1.87638796 |
| 12 | TAOK3 | 1.80643836 |
| 13 | CSK | 1.79482377 |
| 14 | TYK2 | 1.78840483 |
| 15 | MAP3K11 | 1.69255124 |
| 16 | MAP3K13 | 1.53834390 |
| 17 | TAOK1 | 1.50603833 |
| 18 | PNCK | 1.41193810 |
| 19 | SIK3 | 1.38997560 |
| 20 | MAPK15 | 1.37750518 |
| 21 | PRPF4B | 1.35784979 |
| 22 | MAP3K3 | 1.33830918 |
| 23 | JAK3 | 1.33821540 |
| 24 | FGR | 1.33532132 |
| 25 | ARAF | 1.32075998 |
| 26 | ZAP70 | 1.22315136 |
| 27 | TAOK2 | 1.19641246 |
| 28 | IRAK1 | 1.19432287 |
| 29 | TBK1 | 1.19376989 |
| 30 | EPHB1 | 1.13636758 |
| 31 | IKBKE | 1.11873930 |
| 32 | HCK | 1.11076719 |
| 33 | MAP3K5 | 1.09899667 |
| 34 | TXK | 1.07211769 |
| 35 | GRK6 | 1.05125669 |
| 36 | RAF1 | 0.99320092 |
| 37 | MAP3K1 | 0.97717507 |
| 38 | LYN | 0.96771638 |
| 39 | IKBKB | 0.95562158 |
| 40 | MAP3K14 | 0.94831913 |
| 41 | KSR2 | 0.94278563 |
| 42 | JAK2 | 0.93366208 |
| 43 | MARK2 | 0.91271147 |
| 44 | MOS | 0.89545384 |
| 45 | BTK | 0.89119344 |
| 46 | SYK | 0.85978499 |
| 47 | GRK7 | 0.83460919 |
| 48 | MAPKAPK3 | 0.75490377 |
| 49 | PDK2 | 0.74731543 |
| 50 | LCK | 0.73468610 |
| 51 | CSF1R | 0.70576754 |
| 52 | SIK2 | 0.67207748 |
| 53 | YES1 | 0.65632339 |
| 54 | EIF2AK3 | 0.62811322 |
| 55 | BMPR2 | 0.61244850 |
| 56 | WNK4 | 0.61064368 |
| 57 | JAK1 | 0.58762232 |
| 58 | PIM2 | 0.58629319 |
| 59 | MARK3 | 0.57386244 |
| 60 | TESK2 | 0.55363132 |
| 61 | PDK1 | 0.54003515 |
| 62 | PRKCD | 0.53425509 |
| 63 | SIK1 | 0.51407520 |
| 64 | PDPK1 | 0.50618429 |
| 65 | BRD4 | 0.50055384 |
| 66 | IRAK2 | 0.49938426 |
| 67 | MAP2K6 | 0.48857494 |
| 68 | MATK | 0.48431608 |
| 69 | TGFBR2 | 0.48213655 |
| 70 | PTK2B | 0.47218302 |
| 71 | KSR1 | 0.45974680 |
| 72 | PRKD2 | 0.42863513 |
| 73 | KIT | 0.42071535 |
| 74 | DYRK1B | 0.41297025 |
| 75 | STK10 | 0.39150064 |
| 76 | MAP2K4 | 0.38129722 |
| 77 | MAPKAPK2 | 0.37026735 |
| 78 | MAP3K6 | 0.36686633 |
| 79 | EPHA3 | 0.36489507 |
| 80 | MAPK12 | 0.31163027 |
| 81 | FYN | 0.31038538 |
| 82 | ITK | 0.30833805 |
| 83 | PIM1 | 0.30527447 |
| 84 | CHUK | 0.29319607 |
| 85 | PRKD1 | 0.29178994 |
| 86 | STK11 | 0.27093948 |
| 87 | WNK1 | 0.27076326 |
| 88 | PRKG2 | 0.25598166 |
| 89 | PIK3CG | 0.24413667 |
| 90 | RET | 0.24141644 |
| 91 | PDGFRB | 0.21943925 |
| 92 | MAP2K2 | 0.21389211 |
| 93 | MAP3K7 | 0.21109626 |
| 94 | PTK6 | 0.20220968 |
| 95 | MTOR | 0.19134914 |
| 96 | CDC42BPA | 0.18822917 |
| 97 | PRKCQ | 0.18785180 |
| 98 | MAPK7 | 0.18726782 |
| 99 | DAPK2 | 0.18177908 |
| 100 | PKN1 | 0.17547305 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | * Legionellosis_Homo sapiens_hsa05134 | 2.99312427 |
| 2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.78209783 |
| 3 | Leishmaniasis_Homo sapiens_hsa05140 | 2.75111700 |
| 4 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.72350268 |
| 5 | * Influenza A_Homo sapiens_hsa05164 | 2.46342815 |
| 6 | * Antigen processing and presentation_Homo sapiens_hsa04612 | 2.35017446 |
| 7 | Other glycan degradation_Homo sapiens_hsa00511 | 2.32741467 |
| 8 | Tuberculosis_Homo sapiens_hsa05152 | 2.24230088 |
| 9 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.21017581 |
| 10 | Allograft rejection_Homo sapiens_hsa05330 | 2.16084776 |
| 11 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.10476419 |
| 12 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.07166157 |
| 13 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.90524455 |
| 14 | Malaria_Homo sapiens_hsa05144 | 1.84079998 |
| 15 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.81811732 |
| 16 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.79506557 |
| 17 | * Toxoplasmosis_Homo sapiens_hsa05145 | 1.77357884 |
| 18 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.77309913 |
| 19 | * Measles_Homo sapiens_hsa05162 | 1.76447202 |
| 20 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.71800180 |
| 21 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.70961345 |
| 22 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.69696783 |
| 23 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.66388150 |
| 24 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.63313605 |
| 25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.60414264 |
| 26 | Phagosome_Homo sapiens_hsa04145 | 1.57203241 |
| 27 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.48436637 |
| 28 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.47535151 |
| 29 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.46221239 |
| 30 | * Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.45132326 |
| 31 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.39820805 |
| 32 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.37537674 |
| 33 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.35538049 |
| 34 | Prion diseases_Homo sapiens_hsa05020 | 1.34997995 |
| 35 | Viral myocarditis_Homo sapiens_hsa05416 | 1.33330420 |
| 36 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.31375460 |
| 37 | Salmonella infection_Homo sapiens_hsa05132 | 1.29995547 |
| 38 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.29537330 |
| 39 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.29507727 |
| 40 | Lysosome_Homo sapiens_hsa04142 | 1.28523078 |
| 41 | Pertussis_Homo sapiens_hsa05133 | 1.26674324 |
| 42 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.25429021 |
| 43 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.25062404 |
| 44 | Asthma_Homo sapiens_hsa05310 | 1.24343858 |
| 45 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.18062378 |
| 46 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.16037774 |
| 47 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.13651620 |
| 48 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.10733206 |
| 49 | * Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.08831764 |
| 50 | Hepatitis B_Homo sapiens_hsa05161 | 1.04347354 |
| 51 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.04057560 |
| 52 | * Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.01399688 |
| 53 | Proteasome_Homo sapiens_hsa03050 | 1.01338090 |
| 54 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.00840018 |
| 55 | Protein export_Homo sapiens_hsa03060 | 0.99612353 |
| 56 | * Endocytosis_Homo sapiens_hsa04144 | 0.99220799 |
| 57 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.96623869 |
| 58 | Apoptosis_Homo sapiens_hsa04210 | 0.95453477 |
| 59 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.95002638 |
| 60 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.94784048 |
| 61 | Hepatitis C_Homo sapiens_hsa05160 | 0.93410613 |
| 62 | Shigellosis_Homo sapiens_hsa05131 | 0.92532087 |
| 63 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.91213881 |
| 64 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.87628376 |
| 65 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.82163013 |
| 66 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.77538244 |
| 67 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.68994590 |
| 68 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.60964277 |
| 69 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.58500537 |
| 70 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.56732646 |
| 71 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.55825948 |
| 72 | * MAPK signaling pathway_Homo sapiens_hsa04010 | 0.55438501 |
| 73 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.52598689 |
| 74 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.48412945 |
| 75 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.46783020 |
| 76 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.46182976 |
| 77 | Amoebiasis_Homo sapiens_hsa05146 | 0.43609549 |
| 78 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.43277092 |
| 79 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.43050282 |
| 80 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.42962874 |
| 81 | Platelet activation_Homo sapiens_hsa04611 | 0.38711398 |
| 82 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.38683687 |
| 83 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.38228013 |
| 84 | * Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.37794836 |
| 85 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.34749379 |
| 86 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.34432482 |
| 87 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.34402255 |
| 88 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.32735313 |
| 89 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.31886895 |
| 90 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.30628445 |
| 91 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.30198632 |
| 92 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.30155443 |
| 93 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.29765880 |
| 94 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.29433070 |
| 95 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.27765921 |
| 96 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.27105135 |
| 97 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.24789258 |
| 98 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.24698341 |
| 99 | Morphine addiction_Homo sapiens_hsa05032 | 0.20808983 |
| 100 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.19391174 |

