

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.61397121 |
| 2 | negative regulation of cell killing (GO:0031342) | 5.61397121 |
| 3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.51391262 |
| 4 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.39514001 |
| 5 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.39514001 |
| 6 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.39514001 |
| 7 | modulation by symbiont of host immune response (GO:0052553) | 5.39514001 |
| 8 | positive regulation by symbiont of host defense response (GO:0052509) | 5.39514001 |
| 9 | modulation by symbiont of host defense response (GO:0052031) | 5.39514001 |
| 10 | neutrophil activation involved in immune response (GO:0002283) | 5.13814692 |
| 11 | response to peptidoglycan (GO:0032494) | 5.12989870 |
| 12 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.05879688 |
| 13 | macrophage activation involved in immune response (GO:0002281) | 5.02539597 |
| 14 | negative regulation of interleukin-12 production (GO:0032695) | 4.92551986 |
| 15 | detection of other organism (GO:0098543) | 4.79630787 |
| 16 | detection of bacterium (GO:0016045) | 4.63052757 |
| 17 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.61737470 |
| 18 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.51980358 |
| 19 | immunoglobulin mediated immune response (GO:0016064) | 4.32323402 |
| 20 | detection of molecule of bacterial origin (GO:0032490) | 4.22267939 |
| 21 | detection of external biotic stimulus (GO:0098581) | 4.19155615 |
| 22 | regulation of gamma-delta T cell activation (GO:0046643) | 4.16785657 |
| 23 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.09885706 |
| 24 | cellular extravasation (GO:0045123) | 4.00989378 |
| 25 | regulation of mast cell degranulation (GO:0043304) | 3.98822912 |
| 26 | microglial cell activation (GO:0001774) | 3.98201418 |
| 27 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.96914271 |
| 28 | macrophage activation (GO:0042116) | 3.85395631 |
| 29 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.78475056 |
| 30 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.75377751 |
| 31 | response to muramyl dipeptide (GO:0032495) | 3.73372459 |
| 32 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.72732282 |
| 33 | detection of biotic stimulus (GO:0009595) | 3.72415642 |
| 34 | neutrophil activation (GO:0042119) | 3.71536384 |
| 35 | leukocyte aggregation (GO:0070486) | 3.69128866 |
| 36 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.65605366 |
| 37 | response to host immune response (GO:0052572) | 3.61214788 |
| 38 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.61214788 |
| 39 | positive regulation of mast cell activation (GO:0033005) | 3.61152338 |
| 40 | granulocyte activation (GO:0036230) | 3.60851350 |
| 41 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.59841246 |
| 42 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.59756570 |
| 43 | respiratory burst (GO:0045730) | 3.57948140 |
| 44 | germinal center formation (GO:0002467) | 3.54905219 |
| 45 | myeloid cell activation involved in immune response (GO:0002275) | 3.53306386 |
| 46 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.49873078 |
| 47 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.48962709 |
| 48 | cellular response to type I interferon (GO:0071357) | 3.48245843 |
| 49 | type I interferon signaling pathway (GO:0060337) | 3.48245843 |
| 50 | response to type I interferon (GO:0034340) | 3.48151819 |
| 51 | regulation of leukocyte degranulation (GO:0043300) | 3.44894188 |
| 52 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.43690484 |
| 53 | regulation of mast cell activation (GO:0033003) | 3.41999196 |
| 54 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.39038970 |
| 55 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.37371809 |
| 56 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.36717884 |
| 57 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.36199329 |
| 58 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.35610373 |
| 59 | negative regulation of T cell mediated immunity (GO:0002710) | 3.34594293 |
| 60 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.34564624 |
| 61 | positive regulation of mast cell degranulation (GO:0043306) | 3.34564624 |
| 62 | defense response to protozoan (GO:0042832) | 3.34464715 |
| 63 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.33878205 |
| 64 | response to host (GO:0075136) | 3.32816247 |
| 65 | response to host defenses (GO:0052200) | 3.32816247 |
| 66 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.32816247 |
| 67 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.31250748 |
| 68 | regulation of T cell tolerance induction (GO:0002664) | 3.25399739 |
| 69 | B cell mediated immunity (GO:0019724) | 3.24902888 |
| 70 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.23192037 |
| 71 | regulation of antigen processing and presentation (GO:0002577) | 3.21608830 |
| 72 | positive regulation of antigen processing and presentation (GO:0002579) | 3.14309751 |
| 73 | response to protozoan (GO:0001562) | 3.08737520 |
| 74 | regulation of tolerance induction (GO:0002643) | 3.08401385 |
| 75 | T-helper 1 type immune response (GO:0042088) | 3.05376308 |
| 76 | NIK/NF-kappaB signaling (GO:0038061) | 2.99020157 |
| 77 | positive regulation of interferon-alpha production (GO:0032727) | 2.98700646 |
| 78 | regulation of interferon-alpha production (GO:0032647) | 2.98260862 |
| 79 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.97395293 |
| 80 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.97277923 |
| 81 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.96748025 |
| 82 | positive regulation of type 2 immune response (GO:0002830) | 2.96664845 |
| 83 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.96440593 |
| 84 | negative regulation of innate immune response (GO:0045824) | 2.94920355 |
| 85 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.92145304 |
| 86 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.85167777 |
| 87 | regulation of regulated secretory pathway (GO:1903305) | 2.84967911 |
| 88 | B cell receptor signaling pathway (GO:0050853) | 2.81338310 |
| 89 | positive thymic T cell selection (GO:0045059) | 2.81309233 |
| 90 | positive regulation of B cell differentiation (GO:0045579) | 2.79441082 |
| 91 | myeloid leukocyte activation (GO:0002274) | 2.78681713 |
| 92 | regulation of type 2 immune response (GO:0002828) | 2.78568598 |
| 93 | negative regulation of alpha-beta T cell activation (GO:0046636) | 2.78156603 |
| 94 | negative regulation of interleukin-6 production (GO:0032715) | 2.77431997 |
| 95 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.76813452 |
| 96 | neutrophil mediated immunity (GO:0002446) | 2.75842780 |
| 97 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 2.71682217 |
| 98 | T cell migration (GO:0072678) | 2.71391899 |
| 99 | negative regulation of type 2 immune response (GO:0002829) | 2.70610836 |
| 100 | leukocyte degranulation (GO:0043299) | 2.69904498 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.35463331 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.61949378 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.17611445 |
| 4 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.27844765 |
| 5 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.26052473 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.23481959 |
| 7 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.12764996 |
| 8 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.85103417 |
| 9 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.83621332 |
| 10 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.77803437 |
| 11 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.66996459 |
| 12 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.58842146 |
| 13 | SPI1_23127762_ChIP-Seq_K562_Human | 2.48574167 |
| 14 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.43689005 |
| 15 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.38314189 |
| 16 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.34448424 |
| 17 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.29353540 |
| 18 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.28908951 |
| 19 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.25571755 |
| 20 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.25529509 |
| 21 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.21682120 |
| 22 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.18792327 |
| 23 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.18131882 |
| 24 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.18011682 |
| 25 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.16807671 |
| 26 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.12721251 |
| 27 | MAF_26560356_Chip-Seq_TH1_Human | 2.12613029 |
| 28 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.07588364 |
| 29 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.06118659 |
| 30 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.02908775 |
| 31 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.02750095 |
| 32 | MYC_22102868_ChIP-Seq_BL_Human | 2.01357614 |
| 33 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.97466258 |
| 34 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.97250106 |
| 35 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.89671480 |
| 36 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.84887635 |
| 37 | UTX_26944678_Chip-Seq_JUKART_Human | 1.82573782 |
| 38 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.81980563 |
| 39 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.80737236 |
| 40 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.80512073 |
| 41 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.80372519 |
| 42 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.74066752 |
| 43 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.73889310 |
| 44 | * MYB_26560356_Chip-Seq_TH2_Human | 1.73249587 |
| 45 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.72964777 |
| 46 | MAF_26560356_Chip-Seq_TH2_Human | 1.64842072 |
| 47 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.57151498 |
| 48 | MYB_26560356_Chip-Seq_TH1_Human | 1.50717642 |
| 49 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.47075344 |
| 50 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.46578416 |
| 51 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.46178839 |
| 52 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.44773085 |
| 53 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.39519596 |
| 54 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.35586558 |
| 55 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.35366719 |
| 56 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.34103274 |
| 57 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.32956826 |
| 58 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.30930966 |
| 59 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.30735284 |
| 60 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.29284149 |
| 61 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.27784520 |
| 62 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.27452074 |
| 63 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.26785991 |
| 64 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.25933915 |
| 65 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24931194 |
| 66 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.24805944 |
| 67 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.22988527 |
| 68 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.22745918 |
| 69 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.22508808 |
| 70 | GATA1_19941826_ChIP-Seq_K562_Human | 1.21580330 |
| 71 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.21199908 |
| 72 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.19165014 |
| 73 | * KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.18929173 |
| 74 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.18536198 |
| 75 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.18462188 |
| 76 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.17928909 |
| 77 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.15252917 |
| 78 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.14472003 |
| 79 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.13301245 |
| 80 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.12146803 |
| 81 | GATA1_22025678_ChIP-Seq_K562_Human | 1.09928155 |
| 82 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.07918231 |
| 83 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.03133988 |
| 84 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.02862742 |
| 85 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.00470288 |
| 86 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.99737104 |
| 87 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.99529958 |
| 88 | KDM2B_26808549_Chip-Seq_K562_Human | 0.99127732 |
| 89 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.98889307 |
| 90 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.94815607 |
| 91 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.94491952 |
| 92 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.93250676 |
| 93 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92427297 |
| 94 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.91282376 |
| 95 | * GATA3_26560356_Chip-Seq_TH2_Human | 0.89886052 |
| 96 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.89490581 |
| 97 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.88850777 |
| 98 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.84376797 |
| 99 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.83917780 |
| 100 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.83745565 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.31801467 |
| 2 | MP0003436_decreased_susceptibility_to | 4.11932152 |
| 3 | MP0003303_peritoneal_inflammation | 4.09298856 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.56407193 |
| 5 | MP0006082_CNS_inflammation | 3.15904719 |
| 6 | MP0002419_abnormal_innate_immunity | 3.14536183 |
| 7 | MP0005387_immune_system_phenotype | 2.97683812 |
| 8 | MP0001790_abnormal_immune_system | 2.97683812 |
| 9 | MP0005671_abnormal_response_to | 2.92681003 |
| 10 | MP0009785_altered_susceptibility_to | 2.92039216 |
| 11 | MP0005025_abnormal_response_to | 2.82586078 |
| 12 | MP0005058_abnormal_lysosome_morphology | 2.81631772 |
| 13 | MP0005000_abnormal_immune_tolerance | 2.80202457 |
| 14 | MP0001800_abnormal_humoral_immune | 2.68224908 |
| 15 | MP0000685_abnormal_immune_system | 2.65044698 |
| 16 | MP0002148_abnormal_hypersensitivity_rea | 2.62736659 |
| 17 | MP0002723_abnormal_immune_serum | 2.49072023 |
| 18 | MP0003300_gastrointestinal_ulcer | 2.47873054 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.47828444 |
| 20 | MP0003172_abnormal_lysosome_physiology | 2.46150771 |
| 21 | MP0002420_abnormal_adaptive_immunity | 2.30319177 |
| 22 | MP0001819_abnormal_immune_cell | 2.28761609 |
| 23 | MP0001533_abnormal_skeleton_physiology | 2.21327941 |
| 24 | MP0003191_abnormal_cellular_cholesterol | 1.96857297 |
| 25 | MP0003828_pulmonary_edema | 1.94978876 |
| 26 | MP0009278_abnormal_bone_marrow | 1.94253851 |
| 27 | MP0002405_respiratory_system_inflammati | 1.93711140 |
| 28 | MP0004510_myositis | 1.89132850 |
| 29 | MP0008260_abnormal_autophagy | 1.82962959 |
| 30 | MP0001845_abnormal_inflammatory_respons | 1.76152878 |
| 31 | MP0004947_skin_inflammation | 1.74943086 |
| 32 | MP0005464_abnormal_platelet_physiology | 1.74278531 |
| 33 | MP0000343_altered_response_to | 1.72461122 |
| 34 | MP0003075_altered_response_to | 1.71241269 |
| 35 | MP0010155_abnormal_intestine_physiology | 1.70766324 |
| 36 | MP0000716_abnormal_immune_system | 1.67363097 |
| 37 | MP0009764_decreased_sensitivity_to | 1.66141617 |
| 38 | MP0002998_abnormal_bone_remodeling | 1.55649055 |
| 39 | MP0008469_abnormal_protein_level | 1.55264921 |
| 40 | MP0002398_abnormal_bone_marrow | 1.54025955 |
| 41 | MP0003690_abnormal_glial_cell | 1.51864539 |
| 42 | MP0009840_abnormal_foam_cell | 1.49233877 |
| 43 | MP0009333_abnormal_splenocyte_physiolog | 1.45969961 |
| 44 | MP0003763_abnormal_thymus_physiology | 1.43482024 |
| 45 | MP0005310_abnormal_salivary_gland | 1.41887654 |
| 46 | MP0002132_abnormal_respiratory_system | 1.39452998 |
| 47 | MP0003806_abnormal_nucleotide_metabolis | 1.39057857 |
| 48 | MP0003183_abnormal_peptide_metabolism | 1.38757200 |
| 49 | MP0005451_abnormal_body_composition | 1.36439124 |
| 50 | MP0000858_altered_metastatic_potential | 1.34603347 |
| 51 | MP0000689_abnormal_spleen_morphology | 1.31807738 |
| 52 | MP0001545_abnormal_hematopoietic_system | 1.31698913 |
| 53 | MP0005397_hematopoietic_system_phenotyp | 1.31698913 |
| 54 | MP0001853_heart_inflammation | 1.29688140 |
| 55 | MP0002429_abnormal_blood_cell | 1.28734188 |
| 56 | MP0004883_abnormal_blood_vessel | 1.27011035 |
| 57 | MP0002722_abnormal_immune_system | 1.25235454 |
| 58 | MP0001851_eye_inflammation | 1.24374797 |
| 59 | MP0000465_gastrointestinal_hemorrhage | 1.21772469 |
| 60 | MP0008004_abnormal_stomach_pH | 1.18159264 |
| 61 | MP0000604_amyloidosis | 1.17986993 |
| 62 | MP0005166_decreased_susceptibility_to | 1.15861209 |
| 63 | MP0002933_joint_inflammation | 1.13620864 |
| 64 | MP0002277_abnormal_respiratory_mucosa | 1.10164144 |
| 65 | MP0003866_abnormal_defecation | 1.09126690 |
| 66 | MP0003448_altered_tumor_morphology | 1.08521193 |
| 67 | MP0005164_abnormal_response_to | 1.07513060 |
| 68 | MP0005390_skeleton_phenotype | 1.05602416 |
| 69 | MP0003453_abnormal_keratinocyte_physiol | 0.94547542 |
| 70 | MP0000703_abnormal_thymus_morphology | 0.94324633 |
| 71 | MP0005167_abnormal_blood-brain_barrier | 0.92575508 |
| 72 | MP0004381_abnormal_hair_follicle | 0.89855582 |
| 73 | MP0001663_abnormal_digestive_system | 0.87756992 |
| 74 | MP0009763_increased_sensitivity_to | 0.87442052 |
| 75 | MP0001873_stomach_inflammation | 0.86588694 |
| 76 | MP0000249_abnormal_blood_vessel | 0.79061213 |
| 77 | MP0003795_abnormal_bone_structure | 0.78777293 |
| 78 | MP0002396_abnormal_hematopoietic_system | 0.76158310 |
| 79 | MP0002254_reproductive_system_inflammat | 0.74965983 |
| 80 | MP0003656_abnormal_erythrocyte_physiolo | 0.74749796 |
| 81 | MP0003091_abnormal_cell_migration | 0.74365238 |
| 82 | MP0002332_abnormal_exercise_endurance | 0.74244507 |
| 83 | MP0000920_abnormal_myelination | 0.68337754 |
| 84 | MP0002138_abnormal_hepatobiliary_system | 0.68233003 |
| 85 | MP0001986_abnormal_taste_sensitivity | 0.67062954 |
| 86 | MP0008874_decreased_physiological_sensi | 0.66005359 |
| 87 | MP0001958_emphysema | 0.64777649 |
| 88 | MP0009765_abnormal_xenobiotic_induced | 0.63534445 |
| 89 | MP0003279_aneurysm | 0.59111663 |
| 90 | MP0003221_abnormal_cardiomyocyte_apopto | 0.57117463 |
| 91 | MP0005076_abnormal_cell_differentiation | 0.56937234 |
| 92 | MP0006054_spinal_hemorrhage | 0.56682317 |
| 93 | MP0003705_abnormal_hypodermis_morpholog | 0.54462967 |
| 94 | MP0004808_abnormal_hematopoietic_stem | 0.54155025 |
| 95 | MP0000767_abnormal_smooth_muscle | 0.54095141 |
| 96 | MP0002166_altered_tumor_susceptibility | 0.54086098 |
| 97 | MP0003045_fibrosis | 0.51721137 |
| 98 | MP0001542_abnormal_bone_strength | 0.51293842 |
| 99 | MP0005319_abnormal_enzyme/_coenzyme | 0.50893633 |
| 100 | MP0003329_amyloid_beta_deposits | 0.50882627 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 5.93985154 |
| 2 | Recurrent bacterial skin infections (HP:0005406) | 5.61657327 |
| 3 | Recurrent abscess formation (HP:0002722) | 5.61319653 |
| 4 | Abnormality of macrophages (HP:0004311) | 5.60672947 |
| 5 | Myositis (HP:0100614) | 5.25857889 |
| 6 | Orchitis (HP:0100796) | 5.04740343 |
| 7 | Retrobulbar optic neuritis (HP:0100654) | 4.79558221 |
| 8 | Optic neuritis (HP:0100653) | 4.79558221 |
| 9 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.63080643 |
| 10 | Abnormality of glycolipid metabolism (HP:0010969) | 4.30785526 |
| 11 | Abnormality of liposaccharide metabolism (HP:0010968) | 4.30785526 |
| 12 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 4.30785526 |
| 13 | Stomatitis (HP:0010280) | 4.14484359 |
| 14 | Mediastinal lymphadenopathy (HP:0100721) | 4.04064534 |
| 15 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.87432986 |
| 16 | Recurrent skin infections (HP:0001581) | 3.71740025 |
| 17 | Recurrent fungal infections (HP:0002841) | 3.66633174 |
| 18 | Systemic lupus erythematosus (HP:0002725) | 3.64791320 |
| 19 | Spontaneous hematomas (HP:0007420) | 3.63969036 |
| 20 | Obstructive lung disease (HP:0006536) | 3.62283865 |
| 21 | Chronic obstructive pulmonary disease (HP:0006510) | 3.62283865 |
| 22 | Meningitis (HP:0001287) | 3.55365163 |
| 23 | Increased cerebral lipofuscin (HP:0011813) | 3.52458151 |
| 24 | Keratoconjunctivitis sicca (HP:0001097) | 3.43685833 |
| 25 | Gastrointestinal infarctions (HP:0005244) | 3.36028415 |
| 26 | Dysostosis multiplex (HP:0000943) | 3.30596229 |
| 27 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.24155014 |
| 28 | Recurrent cutaneous fungal infections (HP:0011370) | 3.24155014 |
| 29 | Vasculitis (HP:0002633) | 3.23261367 |
| 30 | Increased IgE level (HP:0003212) | 3.21225821 |
| 31 | Gingivitis (HP:0000230) | 3.20939105 |
| 32 | Encephalitis (HP:0002383) | 3.18661185 |
| 33 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.18542938 |
| 34 | Keratoconjunctivitis (HP:0001096) | 3.13340246 |
| 35 | Loss of speech (HP:0002371) | 3.06806757 |
| 36 | Hemoptysis (HP:0002105) | 3.03001256 |
| 37 | Pulmonary infiltrates (HP:0002113) | 2.98905290 |
| 38 | Colitis (HP:0002583) | 2.91596271 |
| 39 | Amyloidosis (HP:0011034) | 2.89540134 |
| 40 | Vacuolated lymphocytes (HP:0001922) | 2.89292940 |
| 41 | Urticaria (HP:0001025) | 2.89180400 |
| 42 | Inflammation of the large intestine (HP:0002037) | 2.86035856 |
| 43 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.81455471 |
| 44 | Gastrointestinal inflammation (HP:0004386) | 2.75812632 |
| 45 | Prolonged bleeding time (HP:0003010) | 2.75325063 |
| 46 | Cellulitis (HP:0100658) | 2.74786234 |
| 47 | Recurrent viral infections (HP:0004429) | 2.69006561 |
| 48 | Purpura (HP:0000979) | 2.63360699 |
| 49 | Glomerulonephritis (HP:0000099) | 2.58116204 |
| 50 | Increased serum ferritin (HP:0003281) | 2.57458128 |
| 51 | Axonal loss (HP:0003447) | 2.55182188 |
| 52 | Pustule (HP:0200039) | 2.49309392 |
| 53 | Episodic fever (HP:0001954) | 2.48607584 |
| 54 | Chest pain (HP:0100749) | 2.47193351 |
| 55 | Disinhibition (HP:0000734) | 2.46041042 |
| 56 | Petechiae (HP:0000967) | 2.44253908 |
| 57 | Pulmonary embolism (HP:0002204) | 2.43007104 |
| 58 | Hematochezia (HP:0002573) | 2.42586150 |
| 59 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.40846607 |
| 60 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.40846607 |
| 61 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.40846607 |
| 62 | Epistaxis (HP:0000421) | 2.40621217 |
| 63 | Malnutrition (HP:0004395) | 2.36064796 |
| 64 | Arterial thrombosis (HP:0004420) | 2.35712573 |
| 65 | Leukocytosis (HP:0001974) | 2.31000790 |
| 66 | Anorexia (HP:0002039) | 2.29825515 |
| 67 | Hepatosplenomegaly (HP:0001433) | 2.29061731 |
| 68 | Nuclear cataract (HP:0100018) | 2.28974488 |
| 69 | Panhypogammaglobulinemia (HP:0003139) | 2.28702686 |
| 70 | Abnormality of the pleura (HP:0002103) | 2.26520227 |
| 71 | Mucopolysacchariduria (HP:0008155) | 2.25926203 |
| 72 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.25926203 |
| 73 | Abnormality of iron homeostasis (HP:0011031) | 2.24953107 |
| 74 | Peritonitis (HP:0002586) | 2.24717627 |
| 75 | Gastrointestinal stroma tumor (HP:0100723) | 2.24088296 |
| 76 | Osteomyelitis (HP:0002754) | 2.23601200 |
| 77 | T lymphocytopenia (HP:0005403) | 2.21586573 |
| 78 | Mutism (HP:0002300) | 2.20916061 |
| 79 | Gingival bleeding (HP:0000225) | 2.19481114 |
| 80 | Gangrene (HP:0100758) | 2.18219183 |
| 81 | Hypochromic anemia (HP:0001931) | 2.16678769 |
| 82 | Increased IgM level (HP:0003496) | 2.14929138 |
| 83 | Autoimmune thrombocytopenia (HP:0001973) | 2.13199441 |
| 84 | Abnormality of T cell number (HP:0011839) | 2.09561689 |
| 85 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.05830455 |
| 86 | Abnormality of the endocardium (HP:0004306) | 2.03098302 |
| 87 | Lymphopenia (HP:0001888) | 2.02630387 |
| 88 | Neuronal loss in central nervous system (HP:0002529) | 2.01931502 |
| 89 | Hypergammaglobulinemia (HP:0010702) | 2.01777718 |
| 90 | Premature loss of primary teeth (HP:0006323) | 2.01103728 |
| 91 | Restrictive lung disease (HP:0002091) | 2.00709322 |
| 92 | Interstitial pulmonary disease (HP:0006530) | 2.00142049 |
| 93 | Acne (HP:0001061) | 1.99787687 |
| 94 | Vertigo (HP:0002321) | 1.98221197 |
| 95 | Polyneuropathy (HP:0001271) | 1.98083527 |
| 96 | Abnormality of the peritoneum (HP:0002585) | 1.96653472 |
| 97 | Hypochromic microcytic anemia (HP:0004840) | 1.95350301 |
| 98 | Abnormality of T cells (HP:0002843) | 1.93470447 |
| 99 | Glomerulopathy (HP:0100820) | 1.92480526 |
| 100 | Sepsis (HP:0100806) | 1.91108683 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BLK | 4.76459846 |
| 2 | RIPK4 | 4.64157427 |
| 3 | MAP4K1 | 3.22866068 |
| 4 | TYK2 | 2.93924126 |
| 5 | ERN1 | 2.91413319 |
| 6 | IRAK4 | 2.74292214 |
| 7 | CSK | 2.55510287 |
| 8 | MAP2K3 | 2.49947635 |
| 9 | PRPF4B | 2.32600341 |
| 10 | TNK2 | 2.28864358 |
| 11 | FES | 2.14437618 |
| 12 | MAP3K14 | 1.95036097 |
| 13 | ZAP70 | 1.93440260 |
| 14 | TBK1 | 1.89675058 |
| 15 | FGR | 1.89675033 |
| 16 | MAP3K13 | 1.83159304 |
| 17 | MAPK15 | 1.81134432 |
| 18 | MAP3K3 | 1.78744735 |
| 19 | JAK3 | 1.70712079 |
| 20 | TAOK1 | 1.66413397 |
| 21 | IKBKE | 1.60574616 |
| 22 | SYK | 1.57323277 |
| 23 | MAP3K11 | 1.57070799 |
| 24 | EPHB1 | 1.55437790 |
| 25 | BTK | 1.51342050 |
| 26 | HCK | 1.45503083 |
| 27 | CSF1R | 1.39520801 |
| 28 | TGFBR2 | 1.36934401 |
| 29 | GRK6 | 1.36133655 |
| 30 | LYN | 1.36082905 |
| 31 | JAK1 | 1.34946595 |
| 32 | TRIB3 | 1.31981431 |
| 33 | TXK | 1.30505246 |
| 34 | MAP3K1 | 1.23897492 |
| 35 | IKBKB | 1.21078537 |
| 36 | JAK2 | 1.18714540 |
| 37 | GRK7 | 1.17649432 |
| 38 | MATK | 1.17605475 |
| 39 | SIK3 | 1.15781926 |
| 40 | CDC42BPA | 1.15225282 |
| 41 | KIT | 1.13378936 |
| 42 | IRAK3 | 1.13034379 |
| 43 | TAOK2 | 1.07909872 |
| 44 | KSR2 | 1.07657331 |
| 45 | LCK | 1.05983444 |
| 46 | MAP3K6 | 1.03817804 |
| 47 | TAOK3 | 1.01998930 |
| 48 | MARK2 | 0.99536826 |
| 49 | BMPR2 | 0.93209738 |
| 50 | PRKD2 | 0.92800304 |
| 51 | IRAK2 | 0.91272682 |
| 52 | IRAK1 | 0.89616856 |
| 53 | MARK3 | 0.89149124 |
| 54 | YES1 | 0.87967500 |
| 55 | SIK1 | 0.86292983 |
| 56 | PDPK1 | 0.81612243 |
| 57 | ITK | 0.79187276 |
| 58 | SIK2 | 0.77922496 |
| 59 | PDK1 | 0.77187397 |
| 60 | PTK6 | 0.74177432 |
| 61 | MAPK7 | 0.73454714 |
| 62 | MAP3K7 | 0.71937767 |
| 63 | STK10 | 0.69225475 |
| 64 | MAPK12 | 0.66508706 |
| 65 | TEC | 0.63982242 |
| 66 | MAP2K6 | 0.63106661 |
| 67 | MOS | 0.62364933 |
| 68 | FYN | 0.59675993 |
| 69 | RPS6KL1 | 0.58584792 |
| 70 | RPS6KC1 | 0.58584792 |
| 71 | DYRK1B | 0.56438098 |
| 72 | BMX | 0.56011524 |
| 73 | RIPK1 | 0.55875192 |
| 74 | MAP3K2 | 0.54113025 |
| 75 | HIPK2 | 0.50782464 |
| 76 | FGFR4 | 0.50233111 |
| 77 | MAP3K5 | 0.50175137 |
| 78 | RPS6KA6 | 0.50094046 |
| 79 | RET | 0.44995878 |
| 80 | RPS6KA2 | 0.39883479 |
| 81 | CHUK | 0.39289908 |
| 82 | PRKD1 | 0.38207577 |
| 83 | PDGFRB | 0.38086648 |
| 84 | LRRK2 | 0.37709377 |
| 85 | DAPK2 | 0.36664502 |
| 86 | FGFR3 | 0.36305883 |
| 87 | MAPKAPK2 | 0.36173707 |
| 88 | EPHA3 | 0.35581012 |
| 89 | PTK2B | 0.34103594 |
| 90 | CDK19 | 0.33751787 |
| 91 | TESK2 | 0.33648632 |
| 92 | PIM1 | 0.33283089 |
| 93 | PRKCQ | 0.32973941 |
| 94 | MAPK4 | 0.31993286 |
| 95 | STK11 | 0.31121245 |
| 96 | ABL1 | 0.29648471 |
| 97 | TYRO3 | 0.29050249 |
| 98 | KSR1 | 0.28993024 |
| 99 | NME2 | 0.27540776 |
| 100 | DDR2 | 0.27313485 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.30280973 |
| 2 | Leishmaniasis_Homo sapiens_hsa05140 | 3.02858203 |
| 3 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.99753423 |
| 4 | Other glycan degradation_Homo sapiens_hsa00511 | 2.52006358 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.50581841 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.43189407 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.25607021 |
| 8 | Tuberculosis_Homo sapiens_hsa05152 | 2.20164462 |
| 9 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.18749761 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.02997704 |
| 11 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.00689910 |
| 12 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.97278570 |
| 13 | Malaria_Homo sapiens_hsa05144 | 1.94772567 |
| 14 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.90717481 |
| 15 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.87274814 |
| 16 | Asthma_Homo sapiens_hsa05310 | 1.83922421 |
| 17 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.81919620 |
| 18 | Legionellosis_Homo sapiens_hsa05134 | 1.80369603 |
| 19 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.78725904 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.76262699 |
| 21 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.74293125 |
| 22 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.68938378 |
| 23 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.68050199 |
| 24 | Influenza A_Homo sapiens_hsa05164 | 1.65187824 |
| 25 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.64204683 |
| 26 | Lysosome_Homo sapiens_hsa04142 | 1.61883273 |
| 27 | Phagosome_Homo sapiens_hsa04145 | 1.56534545 |
| 28 | Pertussis_Homo sapiens_hsa05133 | 1.56296875 |
| 29 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.55647807 |
| 30 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.54270514 |
| 31 | Measles_Homo sapiens_hsa05162 | 1.52836794 |
| 32 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.51646649 |
| 33 | Viral myocarditis_Homo sapiens_hsa05416 | 1.49840890 |
| 34 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.42857456 |
| 35 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.42640344 |
| 36 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.38868855 |
| 37 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.36247951 |
| 38 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.34829536 |
| 39 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.33322835 |
| 40 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.27301369 |
| 41 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.23594870 |
| 42 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.19994648 |
| 43 | Salmonella infection_Homo sapiens_hsa05132 | 1.16546289 |
| 44 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.14100502 |
| 45 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.10966356 |
| 46 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.00203808 |
| 47 | Hepatitis B_Homo sapiens_hsa05161 | 0.99476994 |
| 48 | Hepatitis C_Homo sapiens_hsa05160 | 0.97156062 |
| 49 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.93171575 |
| 50 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.92800779 |
| 51 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.91870072 |
| 52 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.89509549 |
| 53 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.89371107 |
| 54 | Platelet activation_Homo sapiens_hsa04611 | 0.88425051 |
| 55 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.86717277 |
| 56 | Shigellosis_Homo sapiens_hsa05131 | 0.83890296 |
| 57 | Apoptosis_Homo sapiens_hsa04210 | 0.82611882 |
| 58 | Amoebiasis_Homo sapiens_hsa05146 | 0.75271579 |
| 59 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.74879946 |
| 60 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.74551593 |
| 61 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.72642575 |
| 62 | Prion diseases_Homo sapiens_hsa05020 | 0.71783587 |
| 63 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.68358414 |
| 64 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.67653588 |
| 65 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.65629076 |
| 66 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.65533912 |
| 67 | Endocytosis_Homo sapiens_hsa04144 | 0.65399251 |
| 68 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.64909460 |
| 69 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.64010864 |
| 70 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.63956071 |
| 71 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.62596727 |
| 72 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.62403672 |
| 73 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.59643021 |
| 74 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.57800130 |
| 75 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.56704126 |
| 76 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.54984722 |
| 77 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.50365220 |
| 78 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.49947727 |
| 79 | HTLV-I infection_Homo sapiens_hsa05166 | 0.48072310 |
| 80 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.47313215 |
| 81 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.45749976 |
| 82 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.45272876 |
| 83 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.44921219 |
| 84 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.43826957 |
| 85 | Bladder cancer_Homo sapiens_hsa05219 | 0.43659106 |
| 86 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.40214535 |
| 87 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.39606477 |
| 88 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.39521221 |
| 89 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.39309252 |
| 90 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.38727054 |
| 91 | Insulin resistance_Homo sapiens_hsa04931 | 0.38078673 |
| 92 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.36336262 |
| 93 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.34803855 |
| 94 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.32165256 |
| 95 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.30828476 |
| 96 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.29212952 |
| 97 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.29069748 |
| 98 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.27264575 |
| 99 | Endometrial cancer_Homo sapiens_hsa05213 | 0.25932732 |
| 100 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.25843633 |

