

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.67698575 |
| 2 | cytidine metabolic process (GO:0046087) | 5.33561110 |
| 3 | cytidine catabolic process (GO:0006216) | 5.33561110 |
| 4 | cytidine deamination (GO:0009972) | 5.33561110 |
| 5 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.05567227 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.81378591 |
| 7 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.72312872 |
| 8 | proteasome assembly (GO:0043248) | 4.69181962 |
| 9 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.17477178 |
| 10 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.13710122 |
| 11 | rRNA modification (GO:0000154) | 4.13094061 |
| 12 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.09470215 |
| 13 | ATP synthesis coupled proton transport (GO:0015986) | 4.04603047 |
| 14 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.04603047 |
| 15 | rRNA methylation (GO:0031167) | 3.94871156 |
| 16 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.94412071 |
| 17 | protein neddylation (GO:0045116) | 3.88615998 |
| 18 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.86493026 |
| 19 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.84757398 |
| 20 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.84757398 |
| 21 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.84757398 |
| 22 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.83087356 |
| 23 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.83087356 |
| 24 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.78314305 |
| 25 | cullin deneddylation (GO:0010388) | 3.76136436 |
| 26 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.70487447 |
| 27 | negative regulation of ligase activity (GO:0051352) | 3.70169322 |
| 28 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.70169322 |
| 29 | pseudouridine synthesis (GO:0001522) | 3.68765681 |
| 30 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.66952479 |
| 31 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.66952479 |
| 32 | platelet dense granule organization (GO:0060155) | 3.64311714 |
| 33 | termination of RNA polymerase III transcription (GO:0006386) | 3.63414683 |
| 34 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.63414683 |
| 35 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.61686123 |
| 36 | protein deneddylation (GO:0000338) | 3.59837762 |
| 37 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.47889936 |
| 38 | regulation of chronic inflammatory response (GO:0002676) | 3.47508710 |
| 39 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.42532431 |
| 40 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.42532431 |
| 41 | chaperone-mediated protein transport (GO:0072321) | 3.40084834 |
| 42 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.35903707 |
| 43 | maturation of 5.8S rRNA (GO:0000460) | 3.35110275 |
| 44 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.33822719 |
| 45 | respiratory electron transport chain (GO:0022904) | 3.32880105 |
| 46 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.31832571 |
| 47 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.30715950 |
| 48 | electron transport chain (GO:0022900) | 3.29530943 |
| 49 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.22396090 |
| 50 | positive regulation of ligase activity (GO:0051351) | 3.21518778 |
| 51 | respiratory chain complex IV assembly (GO:0008535) | 3.18210821 |
| 52 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.16197235 |
| 53 | protein complex biogenesis (GO:0070271) | 3.14002118 |
| 54 | DNA double-strand break processing (GO:0000729) | 3.12539223 |
| 55 | signal peptide processing (GO:0006465) | 3.11743088 |
| 56 | positive regulation of cell cycle arrest (GO:0071158) | 3.05975093 |
| 57 | regulation of regulatory T cell differentiation (GO:0045589) | 3.03204382 |
| 58 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.99582661 |
| 59 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.99582661 |
| 60 | isotype switching (GO:0045190) | 2.99582661 |
| 61 | regulation of cellular amine metabolic process (GO:0033238) | 2.96584573 |
| 62 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.95928253 |
| 63 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.94684501 |
| 64 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.94684501 |
| 65 | NADH dehydrogenase complex assembly (GO:0010257) | 2.94684501 |
| 66 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.87877201 |
| 67 | protein-cofactor linkage (GO:0018065) | 2.86078953 |
| 68 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.83986796 |
| 69 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.81869478 |
| 70 | cellular ketone body metabolic process (GO:0046950) | 2.79083375 |
| 71 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.78639118 |
| 72 | fucose catabolic process (GO:0019317) | 2.78383653 |
| 73 | L-fucose metabolic process (GO:0042354) | 2.78383653 |
| 74 | L-fucose catabolic process (GO:0042355) | 2.78383653 |
| 75 | peptidyl-histidine modification (GO:0018202) | 2.77662955 |
| 76 | ribosome assembly (GO:0042255) | 2.77650164 |
| 77 | regulation of ligase activity (GO:0051340) | 2.76330129 |
| 78 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.76018511 |
| 79 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.73658229 |
| 80 | cellular response to interferon-beta (GO:0035458) | 2.70409046 |
| 81 | inner mitochondrial membrane organization (GO:0007007) | 2.69622238 |
| 82 | tRNA processing (GO:0008033) | 2.69104168 |
| 83 | cytochrome complex assembly (GO:0017004) | 2.66112990 |
| 84 | protein refolding (GO:0042026) | 2.64234789 |
| 85 | negative regulation of protein ubiquitination (GO:0031397) | 2.61823652 |
| 86 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.59789949 |
| 87 | rRNA processing (GO:0006364) | 2.57140102 |
| 88 | regulation of cell cycle arrest (GO:0071156) | 2.52381617 |
| 89 | protein targeting to mitochondrion (GO:0006626) | 2.51818490 |
| 90 | ketone body metabolic process (GO:1902224) | 2.51546413 |
| 91 | rRNA metabolic process (GO:0016072) | 2.51068143 |
| 92 | response to interferon-beta (GO:0035456) | 2.51012719 |
| 93 | protein localization to mitochondrion (GO:0070585) | 2.50727073 |
| 94 | negative regulation of cell cycle G1/S phase transition (GO:1902807) | 2.49793721 |
| 95 | negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) | 2.49793721 |
| 96 | histone mRNA metabolic process (GO:0008334) | 2.49167907 |
| 97 | establishment of protein localization to mitochondrion (GO:0072655) | 2.48247848 |
| 98 | positive regulation of interleukin-8 secretion (GO:2000484) | 2.47749775 |
| 99 | tRNA metabolic process (GO:0006399) | 2.47087342 |
| 100 | hydrogen ion transmembrane transport (GO:1902600) | 2.45511846 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.03562795 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.35829767 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.69497237 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.34896499 |
| 5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.13305755 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.02973298 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 3.01594829 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.98720078 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.94399510 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.86664227 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.86364523 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.64385491 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.47219463 |
| 14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.38205042 |
| 15 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.31351069 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.26594105 |
| 17 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.23703731 |
| 18 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.18181382 |
| 19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.09351328 |
| 20 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.09129955 |
| 21 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.06214454 |
| 22 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.02619904 |
| 23 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.00047760 |
| 24 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.99399951 |
| 25 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.97847188 |
| 26 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.90699997 |
| 27 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.89763315 |
| 28 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.86639355 |
| 29 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.85278362 |
| 30 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.76784750 |
| 31 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.71867115 |
| 32 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.71381914 |
| 33 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.71290687 |
| 34 | EWS_26573619_Chip-Seq_HEK293_Human | 1.68300400 |
| 35 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.61721569 |
| 36 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.61441916 |
| 37 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.59658369 |
| 38 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.57187934 |
| 39 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.49596854 |
| 40 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.49146263 |
| 41 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.47217472 |
| 42 | GATA3_26560356_Chip-Seq_TH2_Human | 1.40079089 |
| 43 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.39627384 |
| 44 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.38874628 |
| 45 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.38748484 |
| 46 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.37089509 |
| 47 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.36740610 |
| 48 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.34074883 |
| 49 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.33490357 |
| 50 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.29924968 |
| 51 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.26580891 |
| 52 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.25988147 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.25988147 |
| 54 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.22251219 |
| 55 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21747012 |
| 56 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.20879166 |
| 57 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.20838580 |
| 58 | FUS_26573619_Chip-Seq_HEK293_Human | 1.20464714 |
| 59 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.20430091 |
| 60 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.20014996 |
| 61 | MYB_26560356_Chip-Seq_TH2_Human | 1.20007850 |
| 62 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.18327187 |
| 63 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.18327187 |
| 64 | P300_19829295_ChIP-Seq_ESCs_Human | 1.18322555 |
| 65 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.17879375 |
| 66 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.17865955 |
| 67 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.15426043 |
| 68 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.15048013 |
| 69 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.14237633 |
| 70 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.13405336 |
| 71 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.10172378 |
| 72 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.07396061 |
| 73 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.07303755 |
| 74 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.07115441 |
| 75 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.07102981 |
| 76 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.03856245 |
| 77 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.03805767 |
| 78 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.03631337 |
| 79 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.03266049 |
| 80 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.02378452 |
| 81 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.02143783 |
| 82 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.01973795 |
| 83 | AR_20517297_ChIP-Seq_VCAP_Human | 1.01712187 |
| 84 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.99983183 |
| 85 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.98197512 |
| 86 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.98011711 |
| 87 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.97946093 |
| 88 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.96946813 |
| 89 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.95687573 |
| 90 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.94211675 |
| 91 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.94004359 |
| 92 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.91931726 |
| 93 | NCOR_22424771_ChIP-Seq_293T_Human | 0.91748788 |
| 94 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.91561427 |
| 95 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.91352234 |
| 96 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89459018 |
| 97 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89229547 |
| 98 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.87415061 |
| 99 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.87278182 |
| 100 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.87070049 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.43930187 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.31378985 |
| 3 | MP0009785_altered_susceptibility_to | 2.80823707 |
| 4 | MP0006072_abnormal_retinal_apoptosis | 2.55047150 |
| 5 | MP0002102_abnormal_ear_morphology | 2.48870191 |
| 6 | MP0003806_abnormal_nucleotide_metabolis | 2.23776310 |
| 7 | MP0002166_altered_tumor_susceptibility | 2.22053180 |
| 8 | MP0008875_abnormal_xenobiotic_pharmacok | 2.17312157 |
| 9 | MP0004147_increased_porphyrin_level | 2.17229610 |
| 10 | MP0000685_abnormal_immune_system | 2.15536950 |
| 11 | MP0008058_abnormal_DNA_repair | 2.02490070 |
| 12 | MP0002837_dystrophic_cardiac_calcinosis | 2.01504928 |
| 13 | MP0001873_stomach_inflammation | 1.99547214 |
| 14 | MP0009333_abnormal_splenocyte_physiolog | 1.97140575 |
| 15 | MP0002006_tumorigenesis | 1.94372119 |
| 16 | MP0002148_abnormal_hypersensitivity_rea | 1.91791490 |
| 17 | MP0005645_abnormal_hypothalamus_physiol | 1.89034980 |
| 18 | MP0003763_abnormal_thymus_physiology | 1.77505577 |
| 19 | MP0003786_premature_aging | 1.77272406 |
| 20 | MP0001800_abnormal_humoral_immune | 1.73653849 |
| 21 | MP0008872_abnormal_physiological_respon | 1.71346829 |
| 22 | MP0002876_abnormal_thyroid_physiology | 1.68313457 |
| 23 | MP0005000_abnormal_immune_tolerance | 1.67093966 |
| 24 | MP0005387_immune_system_phenotype | 1.65374564 |
| 25 | MP0001790_abnormal_immune_system | 1.65374564 |
| 26 | MP0001188_hyperpigmentation | 1.62557838 |
| 27 | MP0003195_calcinosis | 1.62412366 |
| 28 | MP0006036_abnormal_mitochondrial_physio | 1.61296854 |
| 29 | MP0010094_abnormal_chromosome_stability | 1.58026143 |
| 30 | MP0005075_abnormal_melanosome_morpholog | 1.52057601 |
| 31 | MP0000372_irregular_coat_pigmentation | 1.51997337 |
| 32 | MP0003011_delayed_dark_adaptation | 1.49228543 |
| 33 | MP0006035_abnormal_mitochondrial_morpho | 1.46765845 |
| 34 | MP0002723_abnormal_immune_serum | 1.45261964 |
| 35 | MP0004957_abnormal_blastocyst_morpholog | 1.45087036 |
| 36 | MP0009697_abnormal_copulation | 1.44210039 |
| 37 | MP0005551_abnormal_eye_electrophysiolog | 1.43066550 |
| 38 | MP0004145_abnormal_muscle_electrophysio | 1.42655559 |
| 39 | MP0004142_abnormal_muscle_tone | 1.41645709 |
| 40 | MP0008877_abnormal_DNA_methylation | 1.39240544 |
| 41 | MP0002420_abnormal_adaptive_immunity | 1.37181192 |
| 42 | MP0003186_abnormal_redox_activity | 1.35061653 |
| 43 | MP0003718_maternal_effect | 1.34765493 |
| 44 | MP0001819_abnormal_immune_cell | 1.33867204 |
| 45 | MP0005253_abnormal_eye_physiology | 1.29014466 |
| 46 | MP0005389_reproductive_system_phenotype | 1.28904359 |
| 47 | MP0005084_abnormal_gallbladder_morpholo | 1.28757719 |
| 48 | MP0001501_abnormal_sleep_pattern | 1.27362102 |
| 49 | MP0006082_CNS_inflammation | 1.26626580 |
| 50 | MP0005025_abnormal_response_to | 1.25356544 |
| 51 | MP0003866_abnormal_defecation | 1.24611693 |
| 52 | MP0002452_abnormal_antigen_presenting | 1.23985962 |
| 53 | MP0001919_abnormal_reproductive_system | 1.22952485 |
| 54 | MP0001853_heart_inflammation | 1.21688971 |
| 55 | MP0001905_abnormal_dopamine_level | 1.17151983 |
| 56 | MP0003646_muscle_fatigue | 1.17130478 |
| 57 | MP0005646_abnormal_pituitary_gland | 1.13344369 |
| 58 | MP0002398_abnormal_bone_marrow | 1.12119164 |
| 59 | MP0002736_abnormal_nociception_after | 1.10139129 |
| 60 | MP0000689_abnormal_spleen_morphology | 1.09775951 |
| 61 | MP0003693_abnormal_embryo_hatching | 1.09619518 |
| 62 | MP0002277_abnormal_respiratory_mucosa | 1.08424078 |
| 63 | MP0009379_abnormal_foot_pigmentation | 1.08248607 |
| 64 | MP0001986_abnormal_taste_sensitivity | 1.07547876 |
| 65 | MP0009764_decreased_sensitivity_to | 1.07307182 |
| 66 | MP0005636_abnormal_mineral_homeostasis | 1.07227027 |
| 67 | MP0002693_abnormal_pancreas_physiology | 1.07134730 |
| 68 | MP0010155_abnormal_intestine_physiology | 1.06738963 |
| 69 | MP0001845_abnormal_inflammatory_respons | 1.02558496 |
| 70 | MP0000716_abnormal_immune_system | 1.02100502 |
| 71 | MP0005174_abnormal_tail_pigmentation | 1.01773439 |
| 72 | MP0002095_abnormal_skin_pigmentation | 1.00626753 |
| 73 | MP0005379_endocrine/exocrine_gland_phen | 1.00049676 |
| 74 | MP0001968_abnormal_touch/_nociception | 0.97332464 |
| 75 | MP0000015_abnormal_ear_pigmentation | 0.96852897 |
| 76 | MP0002138_abnormal_hepatobiliary_system | 0.95122372 |
| 77 | MP0002405_respiratory_system_inflammati | 0.94768678 |
| 78 | MP0001764_abnormal_homeostasis | 0.94757622 |
| 79 | MP0008007_abnormal_cellular_replicative | 0.94127207 |
| 80 | MP0000703_abnormal_thymus_morphology | 0.93880508 |
| 81 | MP0002272_abnormal_nervous_system | 0.93847874 |
| 82 | MP0004885_abnormal_endolymph | 0.93153746 |
| 83 | MP0001485_abnormal_pinna_reflex | 0.91931663 |
| 84 | MP0001529_abnormal_vocalization | 0.89864452 |
| 85 | MP0002160_abnormal_reproductive_system | 0.88932770 |
| 86 | MP0002429_abnormal_blood_cell | 0.88789196 |
| 87 | MP0002722_abnormal_immune_system | 0.88506780 |
| 88 | MP0009046_muscle_twitch | 0.86932781 |
| 89 | MP0005310_abnormal_salivary_gland | 0.86763520 |
| 90 | MP0008469_abnormal_protein_level | 0.85666884 |
| 91 | MP0005332_abnormal_amino_acid | 0.85095910 |
| 92 | MP0005410_abnormal_fertilization | 0.84253084 |
| 93 | MP0002254_reproductive_system_inflammat | 0.83861051 |
| 94 | MP0002933_joint_inflammation | 0.83767113 |
| 95 | MP0003448_altered_tumor_morphology | 0.83189200 |
| 96 | MP0010386_abnormal_urinary_bladder | 0.80298264 |
| 97 | MP0002751_abnormal_autonomic_nervous | 0.79199571 |
| 98 | MP0002163_abnormal_gland_morphology | 0.78192899 |
| 99 | MP0005085_abnormal_gallbladder_physiolo | 0.77915007 |
| 100 | MP0005360_urolithiasis | 0.77667263 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.54604127 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.03125631 |
| 3 | Acute encephalopathy (HP:0006846) | 4.01658234 |
| 4 | Increased CSF lactate (HP:0002490) | 3.95616509 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.93639447 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.91774238 |
| 7 | Aplastic anemia (HP:0001915) | 3.90466741 |
| 8 | IgG deficiency (HP:0004315) | 3.83093104 |
| 9 | 3-Methylglutaconic aciduria (HP:0003535) | 3.63815739 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.62285928 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.54818933 |
| 12 | Lipid accumulation in hepatocytes (HP:0006561) | 3.45629043 |
| 13 | Hepatic necrosis (HP:0002605) | 3.43623564 |
| 14 | Stomatitis (HP:0010280) | 3.29846543 |
| 15 | Hypoproteinemia (HP:0003075) | 3.27193105 |
| 16 | T lymphocytopenia (HP:0005403) | 3.19050345 |
| 17 | Cerebral edema (HP:0002181) | 3.18688789 |
| 18 | Abnormality of T cell number (HP:0011839) | 3.04883338 |
| 19 | Severe combined immunodeficiency (HP:0004430) | 3.03681869 |
| 20 | Increased serum lactate (HP:0002151) | 2.94381788 |
| 21 | Hypothermia (HP:0002045) | 2.87944890 |
| 22 | Methylmalonic acidemia (HP:0002912) | 2.75370319 |
| 23 | Congenital stationary night blindness (HP:0007642) | 2.71531760 |
| 24 | Increased IgM level (HP:0003496) | 2.67354540 |
| 25 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.66384417 |
| 26 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.65215721 |
| 27 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.65215721 |
| 28 | Lactic acidosis (HP:0003128) | 2.64197253 |
| 29 | Renal Fanconi syndrome (HP:0001994) | 2.62955781 |
| 30 | Thyroiditis (HP:0100646) | 2.60244791 |
| 31 | Abnormality of B cell number (HP:0010975) | 2.56871705 |
| 32 | Abnormality of T cells (HP:0002843) | 2.52935591 |
| 33 | B lymphocytopenia (HP:0010976) | 2.49355552 |
| 34 | Abolished electroretinogram (ERG) (HP:0000550) | 2.49184023 |
| 35 | Lethargy (HP:0001254) | 2.49023431 |
| 36 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.48992602 |
| 37 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.47781081 |
| 38 | Combined immunodeficiency (HP:0005387) | 2.45431664 |
| 39 | Methylmalonic aciduria (HP:0012120) | 2.44631179 |
| 40 | Pancytopenia (HP:0001876) | 2.43046880 |
| 41 | Pancreatic cysts (HP:0001737) | 2.42346757 |
| 42 | Optic disc pallor (HP:0000543) | 2.41886493 |
| 43 | Respiratory failure (HP:0002878) | 2.41638017 |
| 44 | Ketoacidosis (HP:0001993) | 2.40989796 |
| 45 | Abnormality of the prostate (HP:0008775) | 2.30763912 |
| 46 | Abnormality of midbrain morphology (HP:0002418) | 2.25650892 |
| 47 | Molar tooth sign on MRI (HP:0002419) | 2.25650892 |
| 48 | Increased intramyocellular lipid droplets (HP:0012240) | 2.24863012 |
| 49 | Degeneration of anterior horn cells (HP:0002398) | 2.21452621 |
| 50 | Abnormality of the anterior horn cell (HP:0006802) | 2.21452621 |
| 51 | Abnormality of the pons (HP:0007361) | 2.21173194 |
| 52 | Hypomagnesemia (HP:0002917) | 2.19424729 |
| 53 | Leukodystrophy (HP:0002415) | 2.18384694 |
| 54 | Congenital, generalized hypertrichosis (HP:0004540) | 2.18345239 |
| 55 | Type I transferrin isoform profile (HP:0003642) | 2.17279370 |
| 56 | True hermaphroditism (HP:0010459) | 2.16115482 |
| 57 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.15085015 |
| 58 | Chronic diarrhea (HP:0002028) | 2.14922821 |
| 59 | Oral leukoplakia (HP:0002745) | 2.14836512 |
| 60 | Exertional dyspnea (HP:0002875) | 2.09918224 |
| 61 | Autoimmune hemolytic anemia (HP:0001890) | 2.05855955 |
| 62 | Decreased central vision (HP:0007663) | 2.05114489 |
| 63 | Pancreatic fibrosis (HP:0100732) | 2.04129516 |
| 64 | Large for gestational age (HP:0001520) | 2.03484968 |
| 65 | Exercise intolerance (HP:0003546) | 2.03147376 |
| 66 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.02891386 |
| 67 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.00164277 |
| 68 | Ketosis (HP:0001946) | 1.99289113 |
| 69 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.98957126 |
| 70 | Renal cortical cysts (HP:0000803) | 1.97791070 |
| 71 | Abnormality of methionine metabolism (HP:0010901) | 1.95876891 |
| 72 | Tongue fasciculations (HP:0001308) | 1.94532787 |
| 73 | Generalized aminoaciduria (HP:0002909) | 1.94287650 |
| 74 | Abnormality of eosinophils (HP:0001879) | 1.94166352 |
| 75 | Hypoplasia of the pons (HP:0012110) | 1.93216015 |
| 76 | Pendular nystagmus (HP:0012043) | 1.92941171 |
| 77 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.91850944 |
| 78 | Recurrent cutaneous fungal infections (HP:0011370) | 1.91850944 |
| 79 | Constricted visual fields (HP:0001133) | 1.90347839 |
| 80 | Abnormality of macular pigmentation (HP:0008002) | 1.89769505 |
| 81 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.89700709 |
| 82 | Abnormality of alanine metabolism (HP:0010916) | 1.89700709 |
| 83 | Hyperalaninemia (HP:0003348) | 1.89700709 |
| 84 | Abnormal glycosylation (HP:0012345) | 1.88935307 |
| 85 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.88935307 |
| 86 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.88935307 |
| 87 | Abnormal protein glycosylation (HP:0012346) | 1.88935307 |
| 88 | Increased muscle lipid content (HP:0009058) | 1.88587958 |
| 89 | Palpitations (HP:0001962) | 1.87386409 |
| 90 | Type II lissencephaly (HP:0007260) | 1.87095145 |
| 91 | Abnormality of T cell physiology (HP:0011840) | 1.85598832 |
| 92 | Nephronophthisis (HP:0000090) | 1.84832455 |
| 93 | Abnormality of the renal cortex (HP:0011035) | 1.84401283 |
| 94 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.82167121 |
| 95 | Glycosuria (HP:0003076) | 1.81895020 |
| 96 | Abnormality of urine glucose concentration (HP:0011016) | 1.81895020 |
| 97 | Abnormality of magnesium homeostasis (HP:0004921) | 1.81758099 |
| 98 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.79741977 |
| 99 | Dicarboxylic aciduria (HP:0003215) | 1.79741977 |
| 100 | Attenuation of retinal blood vessels (HP:0007843) | 1.79496433 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 4.85313230 |
| 2 | TXK | 3.79392375 |
| 3 | MST4 | 3.61237179 |
| 4 | EIF2AK3 | 3.40302872 |
| 5 | VRK2 | 2.74860791 |
| 6 | ZAK | 2.40264412 |
| 7 | EIF2AK1 | 2.18026519 |
| 8 | TAOK3 | 2.12751028 |
| 9 | BUB1 | 2.03689776 |
| 10 | NEK1 | 2.01585869 |
| 11 | VRK1 | 2.00969632 |
| 12 | NUAK1 | 1.98494146 |
| 13 | MAP4K2 | 1.96443584 |
| 14 | BCKDK | 1.96017326 |
| 15 | TLK1 | 1.95140297 |
| 16 | KDR | 1.93488761 |
| 17 | TRIM28 | 1.87846182 |
| 18 | MAP3K12 | 1.84712283 |
| 19 | FRK | 1.82138992 |
| 20 | ADRBK2 | 1.76941301 |
| 21 | WNK4 | 1.60859494 |
| 22 | PLK3 | 1.55755304 |
| 23 | TESK2 | 1.53480951 |
| 24 | GRK1 | 1.52593498 |
| 25 | WNK3 | 1.49884915 |
| 26 | ITK | 1.39269461 |
| 27 | TAF1 | 1.36210110 |
| 28 | TEC | 1.35141677 |
| 29 | STK39 | 1.28726804 |
| 30 | SRPK1 | 1.28382625 |
| 31 | BMPR1B | 1.27894550 |
| 32 | PASK | 1.20619242 |
| 33 | MKNK2 | 1.16199886 |
| 34 | OXSR1 | 1.06562583 |
| 35 | MAP4K1 | 1.04711582 |
| 36 | WEE1 | 1.04217641 |
| 37 | MAP2K6 | 1.02704030 |
| 38 | PLK4 | 1.00474632 |
| 39 | EIF2AK2 | 0.95412922 |
| 40 | TIE1 | 0.92365735 |
| 41 | CSNK1G3 | 0.90517027 |
| 42 | BCR | 0.89375992 |
| 43 | TESK1 | 0.85223387 |
| 44 | PINK1 | 0.84956286 |
| 45 | STK16 | 0.83365273 |
| 46 | FES | 0.82846702 |
| 47 | ERBB3 | 0.81284448 |
| 48 | ACVR1B | 0.81121542 |
| 49 | PLK2 | 0.80562590 |
| 50 | CSNK1G1 | 0.80172847 |
| 51 | DAPK1 | 0.78581635 |
| 52 | SCYL2 | 0.78165742 |
| 53 | INSRR | 0.76247347 |
| 54 | MKNK1 | 0.76060719 |
| 55 | CSNK1G2 | 0.74967484 |
| 56 | NME1 | 0.72088388 |
| 57 | PRKCQ | 0.70419964 |
| 58 | PNCK | 0.68842160 |
| 59 | PIM2 | 0.68213563 |
| 60 | IKBKB | 0.66773987 |
| 61 | CSNK1A1L | 0.66272623 |
| 62 | RPS6KA4 | 0.64689768 |
| 63 | MYLK | 0.63675218 |
| 64 | CDC7 | 0.57149934 |
| 65 | SYK | 0.57062666 |
| 66 | RPS6KA5 | 0.56664467 |
| 67 | PLK1 | 0.56432062 |
| 68 | GRK7 | 0.56134287 |
| 69 | BMPR2 | 0.55631153 |
| 70 | LIMK1 | 0.55363129 |
| 71 | MAPKAPK5 | 0.53379133 |
| 72 | PBK | 0.52726713 |
| 73 | DYRK2 | 0.51331840 |
| 74 | KIT | 0.46459079 |
| 75 | TTK | 0.46291494 |
| 76 | MAP3K4 | 0.45887903 |
| 77 | STK38L | 0.42655379 |
| 78 | ADRBK1 | 0.42640863 |
| 79 | CCNB1 | 0.40787210 |
| 80 | LCK | 0.40670936 |
| 81 | MAPK15 | 0.39776377 |
| 82 | PRKCE | 0.39422678 |
| 83 | PHKG1 | 0.38540825 |
| 84 | PHKG2 | 0.38540825 |
| 85 | AKT3 | 0.38104436 |
| 86 | MAPKAPK3 | 0.37972138 |
| 87 | ATR | 0.37374881 |
| 88 | SIK3 | 0.36951261 |
| 89 | ALK | 0.36532835 |
| 90 | MAP2K7 | 0.35553688 |
| 91 | LYN | 0.34889457 |
| 92 | CSNK2A1 | 0.34737259 |
| 93 | CSNK2A2 | 0.34322120 |
| 94 | DAPK2 | 0.34133789 |
| 95 | TNIK | 0.32691595 |
| 96 | IGF1R | 0.29321141 |
| 97 | IKBKE | 0.27613635 |
| 98 | PRKCI | 0.27281678 |
| 99 | BRSK2 | 0.27092568 |
| 100 | BTK | 0.26675331 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.11923663 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.49238635 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.25996485 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.76429521 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.71255610 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.70062004 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.50174457 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.36386864 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.31871880 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.24165658 |
| 11 | Asthma_Homo sapiens_hsa05310 | 2.07648097 |
| 12 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.00981827 |
| 13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.93151327 |
| 14 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.91696552 |
| 15 | Alzheimers disease_Homo sapiens_hsa05010 | 1.75350688 |
| 16 | Huntingtons disease_Homo sapiens_hsa05016 | 1.74782368 |
| 17 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.73440104 |
| 18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.72306145 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.71735943 |
| 20 | Basal transcription factors_Homo sapiens_hsa03022 | 1.58656918 |
| 21 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.58501427 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.55828133 |
| 23 | Ribosome_Homo sapiens_hsa03010 | 1.53527102 |
| 24 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.52290475 |
| 25 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.49531277 |
| 26 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.48621562 |
| 27 | Mismatch repair_Homo sapiens_hsa03430 | 1.43975225 |
| 28 | Homologous recombination_Homo sapiens_hsa03440 | 1.39276883 |
| 29 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.38292371 |
| 30 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.33576098 |
| 31 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.28972360 |
| 32 | RNA transport_Homo sapiens_hsa03013 | 1.28711300 |
| 33 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.28575605 |
| 34 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.24157204 |
| 35 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.23878930 |
| 36 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.23834157 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.19665153 |
| 38 | Spliceosome_Homo sapiens_hsa03040 | 1.17795420 |
| 39 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.13367614 |
| 40 | Phototransduction_Homo sapiens_hsa04744 | 1.11197168 |
| 41 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.07108017 |
| 42 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.03590813 |
| 43 | DNA replication_Homo sapiens_hsa03030 | 1.03452116 |
| 44 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.02617549 |
| 45 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.01723197 |
| 46 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.01392340 |
| 47 | Purine metabolism_Homo sapiens_hsa00230 | 0.97995964 |
| 48 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.96569473 |
| 49 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.93196274 |
| 50 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.90211585 |
| 51 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.89772768 |
| 52 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.89046375 |
| 53 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.85990624 |
| 54 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.85521494 |
| 55 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.83785163 |
| 56 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.81162380 |
| 57 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.79458050 |
| 58 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.77253043 |
| 59 | Peroxisome_Homo sapiens_hsa04146 | 0.74788753 |
| 60 | Measles_Homo sapiens_hsa05162 | 0.67581949 |
| 61 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.66333416 |
| 62 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.65201327 |
| 63 | Legionellosis_Homo sapiens_hsa05134 | 0.63816327 |
| 64 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.62525550 |
| 65 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.60231988 |
| 66 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.60173902 |
| 67 | Viral myocarditis_Homo sapiens_hsa05416 | 0.59218187 |
| 68 | Base excision repair_Homo sapiens_hsa03410 | 0.58758907 |
| 69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.58543516 |
| 70 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.57763822 |
| 71 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.56849088 |
| 72 | Metabolic pathways_Homo sapiens_hsa01100 | 0.55400590 |
| 73 | Sulfur relay system_Homo sapiens_hsa04122 | 0.53018696 |
| 74 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.51737145 |
| 75 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.51673277 |
| 76 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.50008767 |
| 77 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.48437276 |
| 78 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.47820782 |
| 79 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.45936536 |
| 80 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.41777510 |
| 81 | Olfactory transduction_Homo sapiens_hsa04740 | 0.39939217 |
| 82 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.36427026 |
| 83 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.34835168 |
| 84 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.33761300 |
| 85 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.33377118 |
| 86 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.32911357 |
| 87 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.32518163 |
| 88 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.32423406 |
| 89 | Retinol metabolism_Homo sapiens_hsa00830 | 0.31883739 |
| 90 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.29415652 |
| 91 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.28429349 |
| 92 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.28176208 |
| 93 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.27935760 |
| 94 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.26360385 |
| 95 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.25973324 |
| 96 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.25502451 |
| 97 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.25144454 |
| 98 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22591826 |
| 99 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.21796582 |
| 100 | Mineral absorption_Homo sapiens_hsa04978 | 0.21389291 |

