

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of protein sumoylation (GO:0033235) | 9.79367284 |
| 2 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 9.67968061 |
| 3 | synaptic transmission, dopaminergic (GO:0001963) | 9.39126607 |
| 4 | peptidyl-histidine modification (GO:0018202) | 9.15918411 |
| 5 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 8.12179429 |
| 6 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254) | 7.26423896 |
| 7 | regulation of protein sumoylation (GO:0033233) | 6.45013477 |
| 8 | negative regulation of mast cell activation (GO:0033004) | 6.08610184 |
| 9 | keratinocyte development (GO:0003334) | 5.87542756 |
| 10 | regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253) | 5.87248369 |
| 11 | tryptophan catabolic process (GO:0006569) | 5.77240629 |
| 12 | indole-containing compound catabolic process (GO:0042436) | 5.77240629 |
| 13 | indolalkylamine catabolic process (GO:0046218) | 5.77240629 |
| 14 | centriole replication (GO:0007099) | 5.55683668 |
| 15 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 5.47329438 |
| 16 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 5.47024825 |
| 17 | tryptophan metabolic process (GO:0006568) | 5.39773804 |
| 18 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 5.15346958 |
| 19 | tumor necrosis factor-mediated signaling pathway (GO:0033209) | 5.15333022 |
| 20 | regulation of cAMP-mediated signaling (GO:0043949) | 5.06862132 |
| 21 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 4.94987930 |
| 22 | regulation of Wnt signaling pathway involved in heart development (GO:0003307) | 4.93915273 |
| 23 | positive regulation of interleukin-1 secretion (GO:0050716) | 4.82846043 |
| 24 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 4.76995787 |
| 25 | establishment of skin barrier (GO:0061436) | 4.72889626 |
| 26 | hair follicle development (GO:0001942) | 4.68340384 |
| 27 | regulation of action potential (GO:0098900) | 4.57155677 |
| 28 | regulation of interleukin-1 beta secretion (GO:0050706) | 4.55677801 |
| 29 | negative regulation of signal transduction by p53 class mediator (GO:1901797) | 4.53957208 |
| 30 | amyloid precursor protein catabolic process (GO:0042987) | 4.47797167 |
| 31 | DNA damage induced protein phosphorylation (GO:0006975) | 4.32158953 |
| 32 | GMP metabolic process (GO:0046037) | 4.31977805 |
| 33 | positive regulation of DNA-templated transcription, elongation (GO:0032786) | 4.28917861 |
| 34 | receptor recycling (GO:0001881) | 4.19012030 |
| 35 | deoxyribonucleoside diphosphate metabolic process (GO:0009186) | 4.05951676 |
| 36 | peroxisome fission (GO:0016559) | 4.01946772 |
| 37 | regulation of interleukin-1 secretion (GO:0050704) | 3.97037331 |
| 38 | nucleoside diphosphate catabolic process (GO:0009134) | 3.91868151 |
| 39 | mitochondrial calcium ion transport (GO:0006851) | 3.83224240 |
| 40 | regulation of female gonad development (GO:2000194) | 3.81908523 |
| 41 | indolalkylamine metabolic process (GO:0006586) | 3.76446344 |
| 42 | pituitary gland development (GO:0021983) | 3.73943358 |
| 43 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902230) | 3.73050203 |
| 44 | positive regulation of neural precursor cell proliferation (GO:2000179) | 3.72053418 |
| 45 | centriole assembly (GO:0098534) | 3.70261240 |
| 46 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.62041191 |
| 47 | auditory receptor cell stereocilium organization (GO:0060088) | 3.54705243 |
| 48 | respiratory chain complex IV assembly (GO:0008535) | 3.51814845 |
| 49 | regulation of water loss via skin (GO:0033561) | 3.48124733 |
| 50 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 3.43872549 |
| 51 | muscle atrophy (GO:0014889) | 3.40153754 |
| 52 | positive regulation of mitochondrial fission (GO:0090141) | 3.38729801 |
| 53 | positive regulation of epidermis development (GO:0045684) | 3.38092600 |
| 54 | RNA localization (GO:0006403) | 3.37293666 |
| 55 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.35886008 |
| 56 | epithelial cell maturation (GO:0002070) | 3.35806422 |
| 57 | positive regulation of interleukin-1 beta production (GO:0032731) | 3.34718865 |
| 58 | cellular biogenic amine catabolic process (GO:0042402) | 3.33002237 |
| 59 | amine catabolic process (GO:0009310) | 3.33002237 |
| 60 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.30858442 |
| 61 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.30858442 |
| 62 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.30858442 |
| 63 | cell migration involved in gastrulation (GO:0042074) | 3.29203301 |
| 64 | negative regulation of monooxygenase activity (GO:0032769) | 3.27277805 |
| 65 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.24439622 |
| 66 | negative regulation of DNA repair (GO:0045738) | 3.17041466 |
| 67 | behavioral response to nicotine (GO:0035095) | 3.16868003 |
| 68 | pseudouridine synthesis (GO:0001522) | 3.13237348 |
| 69 | cellular response to reactive nitrogen species (GO:1902170) | 3.11858233 |
| 70 | hair cycle process (GO:0022405) | 3.07039477 |
| 71 | molting cycle process (GO:0022404) | 3.07039477 |
| 72 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.05158649 |
| 73 | regulation of protein polyubiquitination (GO:1902914) | 2.96646803 |
| 74 | radial glial cell differentiation (GO:0060019) | 2.95523711 |
| 75 | pantothenate metabolic process (GO:0015939) | 2.94295726 |
| 76 | negative regulation of response to DNA damage stimulus (GO:2001021) | 2.94181820 |
| 77 | ribosomal small subunit biogenesis (GO:0042274) | 2.92989662 |
| 78 | positive regulation of interleukin-1 production (GO:0032732) | 2.88480397 |
| 79 | negative regulation of phosphoprotein phosphatase activity (GO:0032515) | 2.86560101 |
| 80 | UTP biosynthetic process (GO:0006228) | 2.84577763 |
| 81 | positive regulation of CREB transcription factor activity (GO:0032793) | 2.83394445 |
| 82 | aromatic amino acid family catabolic process (GO:0009074) | 2.82831323 |
| 83 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902229) | 2.82034765 |
| 84 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.80557254 |
| 85 | ATP synthesis coupled proton transport (GO:0015986) | 2.79439357 |
| 86 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.79439357 |
| 87 | inositol metabolic process (GO:0006020) | 2.79348905 |
| 88 | regulation of histone deacetylation (GO:0031063) | 2.77678422 |
| 89 | regulation of DNA-templated transcription, elongation (GO:0032784) | 2.77208969 |
| 90 | negative regulation of G2/M transition of mitotic cell cycle (GO:0010972) | 2.76038540 |
| 91 | peristalsis (GO:0030432) | 2.72595830 |
| 92 | neuron remodeling (GO:0016322) | 2.71640829 |
| 93 | mitochondrial fusion (GO:0008053) | 2.70205831 |
| 94 | mitochondrion morphogenesis (GO:0070584) | 2.69914150 |
| 95 | negative regulation of translational initiation (GO:0045947) | 2.69630257 |
| 96 | formation of translation preinitiation complex (GO:0001731) | 2.68712571 |
| 97 | poly(A)+ mRNA export from nucleus (GO:0016973) | 2.66502353 |
| 98 | regulation of steroid hormone secretion (GO:2000831) | 2.65671330 |
| 99 | cytochrome complex assembly (GO:0017004) | 2.64222989 |
| 100 | snRNA transcription (GO:0009301) | 11.1237920 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZNF263_19887448_ChIP-Seq_K562_Human | 5.23644312 |
| 2 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 4.26593659 |
| 3 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.35497673 |
| 4 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 3.18220553 |
| 5 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.12997332 |
| 6 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.90174446 |
| 7 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 2.87420985 |
| 8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.83879710 |
| 9 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.80919351 |
| 10 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.76950166 |
| 11 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.59869682 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.54266865 |
| 13 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 2.48722245 |
| 14 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 2.45497545 |
| 15 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.42590969 |
| 16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.36989768 |
| 17 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.33721344 |
| 18 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.27463494 |
| 19 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.19109365 |
| 20 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.19097986 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.15851634 |
| 22 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.09661629 |
| 23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.04500607 |
| 24 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.99080376 |
| 25 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.96197757 |
| 26 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.91629230 |
| 27 | GATA1_22025678_ChIP-Seq_K562_Human | 1.84900187 |
| 28 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.78793942 |
| 29 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.77599034 |
| 30 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.72954338 |
| 31 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.72877935 |
| 32 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.68706001 |
| 33 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.68024979 |
| 34 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.65364661 |
| 35 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.59272335 |
| 36 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.54715053 |
| 37 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.53993205 |
| 38 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.53725387 |
| 39 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.52354885 |
| 40 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.50776320 |
| 41 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.48671585 |
| 42 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.47149065 |
| 43 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.46869847 |
| 44 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.44718359 |
| 45 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.40538968 |
| 46 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.37177310 |
| 47 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.35489807 |
| 48 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.29768676 |
| 49 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.28626353 |
| 50 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.25317721 |
| 51 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.24370892 |
| 52 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.22132436 |
| 53 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.19509904 |
| 54 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.19453186 |
| 55 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.19059350 |
| 56 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 1.18648980 |
| 57 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.18222567 |
| 58 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.16304855 |
| 59 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.15226150 |
| 60 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.14809999 |
| 61 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.14640028 |
| 62 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.12564920 |
| 63 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.11014640 |
| 64 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.10916659 |
| 65 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.08956853 |
| 66 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.08280639 |
| 67 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.07607520 |
| 68 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.07040993 |
| 69 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.04816117 |
| 70 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.02783437 |
| 71 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.02614119 |
| 72 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.01389173 |
| 73 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.99930240 |
| 74 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.99642469 |
| 75 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.99039571 |
| 76 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.98774060 |
| 77 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.98730700 |
| 78 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.98180573 |
| 79 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.97847724 |
| 80 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.95512905 |
| 81 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.95213391 |
| 82 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.94823981 |
| 83 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.93150074 |
| 84 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.92580430 |
| 85 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.92411207 |
| 86 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.92075394 |
| 87 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.91916721 |
| 88 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.91001810 |
| 89 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.90697475 |
| 90 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.90540794 |
| 91 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.89247003 |
| 92 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.88817153 |
| 93 | FUS_26573619_Chip-Seq_HEK293_Human | 0.88519473 |
| 94 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.88438232 |
| 95 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.87810285 |
| 96 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.87756654 |
| 97 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.87158156 |
| 98 | NFYA_21822215_ChIP-Seq_K562_Human | 0.87143206 |
| 99 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.86376289 |
| 100 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.85396200 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005408_hypopigmentation | 6.73728104 |
| 2 | MP0000579_abnormal_nail_morphology | 4.46413773 |
| 3 | MP0001661_extended_life_span | 3.78351648 |
| 4 | MP0005275_abnormal_skin_tensile | 3.32451964 |
| 5 | MP0000427_abnormal_hair_cycle | 3.06366241 |
| 6 | MP0000383_abnormal_hair_follicle | 2.65418026 |
| 7 | MP0002098_abnormal_vibrissa_morphology | 2.62074869 |
| 8 | MP0005075_abnormal_melanosome_morpholog | 2.31469380 |
| 9 | MP0005451_abnormal_body_composition | 13.7828051 |
| 10 | MP0002837_dystrophic_cardiac_calcinosis | 1.92472788 |
| 11 | MP0002095_abnormal_skin_pigmentation | 1.84713913 |
| 12 | MP0004381_abnormal_hair_follicle | 1.82611636 |
| 13 | MP0002132_abnormal_respiratory_system | 1.76456573 |
| 14 | MP0010678_abnormal_skin_adnexa | 1.73792885 |
| 15 | MP0008260_abnormal_autophagy | 1.57654124 |
| 16 | MP0005083_abnormal_biliary_tract | 1.55312804 |
| 17 | MP0003950_abnormal_plasma_membrane | 1.52490798 |
| 18 | MP0010030_abnormal_orbit_morphology | 1.52268104 |
| 19 | MP0009384_cardiac_valve_regurgitation | 1.45114260 |
| 20 | MP0000647_abnormal_sebaceous_gland | 1.42700083 |
| 21 | MP0002938_white_spotting | 1.40439516 |
| 22 | MP0001348_abnormal_lacrimal_gland | 1.34607831 |
| 23 | MP0008995_early_reproductive_senescence | 1.33756432 |
| 24 | MP0000639_abnormal_adrenal_gland | 1.33265987 |
| 25 | MP0000631_abnormal_neuroendocrine_gland | 1.31896357 |
| 26 | MP0002638_abnormal_pupillary_reflex | 1.31701602 |
| 27 | MP0006035_abnormal_mitochondrial_morpho | 1.30780331 |
| 28 | MP0001186_pigmentation_phenotype | 1.30185862 |
| 29 | MP0003890_abnormal_embryonic-extraembry | 1.29822469 |
| 30 | MP0010094_abnormal_chromosome_stability | 1.27997410 |
| 31 | MP0004147_increased_porphyrin_level | 1.26369306 |
| 32 | MP0008877_abnormal_DNA_methylation | 1.20148765 |
| 33 | MP0000377_abnormal_hair_follicle | 1.18208386 |
| 34 | MP0003787_abnormal_imprinting | 1.16385491 |
| 35 | MP0003786_premature_aging | 1.10415036 |
| 36 | MP0001188_hyperpigmentation | 1.08145110 |
| 37 | MP0002075_abnormal_coat/hair_pigmentati | 1.07500277 |
| 38 | MP0006292_abnormal_olfactory_placode | 1.06517534 |
| 39 | MP0004742_abnormal_vestibular_system | 1.00224894 |
| 40 | MP0003693_abnormal_embryo_hatching | 0.99859002 |
| 41 | MP0000367_abnormal_coat/_hair | 0.95196344 |
| 42 | MP0002254_reproductive_system_inflammat | 0.93041322 |
| 43 | MP0002138_abnormal_hepatobiliary_system | 0.91083271 |
| 44 | MP0001849_ear_inflammation | 0.86487194 |
| 45 | MP0004264_abnormal_extraembryonic_tissu | 0.85439932 |
| 46 | MP0002282_abnormal_trachea_morphology | 0.84917455 |
| 47 | MP0006036_abnormal_mitochondrial_physio | 0.84179661 |
| 48 | MP0005171_absent_coat_pigmentation | 0.82972353 |
| 49 | MP0009703_decreased_birth_body | 0.81445852 |
| 50 | MP0004957_abnormal_blastocyst_morpholog | 0.81407835 |
| 51 | MP0005084_abnormal_gallbladder_morpholo | 0.77467980 |
| 52 | MP0001243_abnormal_dermal_layer | 0.75637480 |
| 53 | MP0002796_impaired_skin_barrier | 0.74201491 |
| 54 | MP0010352_gastrointestinal_tract_polyps | 0.71911051 |
| 55 | MP0001293_anophthalmia | 0.68901941 |
| 56 | MP0004947_skin_inflammation | 0.68556055 |
| 57 | MP0001881_abnormal_mammary_gland | 0.67323857 |
| 58 | MP0004084_abnormal_cardiac_muscle | 0.64321576 |
| 59 | MP0004858_abnormal_nervous_system | 0.63432027 |
| 60 | MP0005076_abnormal_cell_differentiation | 0.61587568 |
| 61 | MP0003172_abnormal_lysosome_physiology | 0.61194102 |
| 62 | MP0008932_abnormal_embryonic_tissue | 0.61110856 |
| 63 | MP0005645_abnormal_hypothalamus_physiol | 0.59943831 |
| 64 | MP0005551_abnormal_eye_electrophysiolog | 0.59604681 |
| 65 | MP0009931_abnormal_skin_appearance | 0.57282263 |
| 66 | MP0004808_abnormal_hematopoietic_stem | 0.57038126 |
| 67 | MP0000358_abnormal_cell_content/ | 0.55840623 |
| 68 | MP0001730_embryonic_growth_arrest | 0.55361611 |
| 69 | MP0003111_abnormal_nucleus_morphology | 0.54559692 |
| 70 | MP0001191_abnormal_skin_condition | 0.53556700 |
| 71 | MP0003806_abnormal_nucleotide_metabolis | 0.53347054 |
| 72 | MP0002970_abnormal_white_adipose | 0.53211002 |
| 73 | MP0002405_respiratory_system_inflammati | 0.52910380 |
| 74 | MP0003656_abnormal_erythrocyte_physiolo | 0.49286932 |
| 75 | MP0000350_abnormal_cell_proliferation | 0.49196388 |
| 76 | MP0001216_abnormal_epidermal_layer | 0.47693379 |
| 77 | MP0002088_abnormal_embryonic_growth/wei | 0.45515806 |
| 78 | MP0003984_embryonic_growth_retardation | 0.44751788 |
| 79 | MP0005670_abnormal_white_adipose | 0.43328290 |
| 80 | MP0001697_abnormal_embryo_size | 0.43120196 |
| 81 | MP0008770_decreased_survivor_rate | 0.42803715 |
| 82 | MP0000627_abnormal_mammary_gland | 0.39188193 |
| 83 | MP0002697_abnormal_eye_size | 0.38916134 |
| 84 | MP0005266_abnormal_metabolism | 0.38631351 |
| 85 | MP0005380_embryogenesis_phenotype | 0.37848534 |
| 86 | MP0001672_abnormal_embryogenesis/_devel | 0.37848534 |
| 87 | MP0001919_abnormal_reproductive_system | 0.36921652 |
| 88 | MP0002295_abnormal_pulmonary_circulatio | 0.35772231 |
| 89 | MP0005174_abnormal_tail_pigmentation | 0.35704556 |
| 90 | MP0000372_irregular_coat_pigmentation | 0.35385914 |
| 91 | MP0002396_abnormal_hematopoietic_system | 0.35371362 |
| 92 | MP0008058_abnormal_DNA_repair | 0.35093374 |
| 93 | MP0009379_abnormal_foot_pigmentation | 0.34334399 |
| 94 | MP0003077_abnormal_cell_cycle | 0.33963028 |
| 95 | MP0005501_abnormal_skin_physiology | 0.33868053 |
| 96 | MP0003121_genomic_imprinting | 0.33642552 |
| 97 | MP0001545_abnormal_hematopoietic_system | 0.32296324 |
| 98 | MP0005397_hematopoietic_system_phenotyp | 0.32296324 |
| 99 | MP0001119_abnormal_female_reproductive | 0.29498060 |
| 100 | MP0010771_integument_phenotype | 0.28816052 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Follicular hyperkeratosis (HP:0007502) | 8.54046964 |
| 2 | Congenital, generalized hypertrichosis (HP:0004540) | 6.86050122 |
| 3 | Adrenal hypoplasia (HP:0000835) | 6.71315247 |
| 4 | Abnormal hair laboratory examination (HP:0003328) | 6.68153061 |
| 5 | Sparse lateral eyebrow (HP:0005338) | 5.61814760 |
| 6 | Slow-growing hair (HP:0002217) | 5.55053882 |
| 7 | Abnormality of hair growth rate (HP:0011363) | 5.55053882 |
| 8 | Woolly hair (HP:0002224) | 5.15325336 |
| 9 | Sparse eyelashes (HP:0000653) | 4.71826870 |
| 10 | Intrahepatic cholestasis (HP:0001406) | 4.33196647 |
| 11 | Concave nail (HP:0001598) | 3.96136814 |
| 12 | Degeneration of anterior horn cells (HP:0002398) | 3.71617120 |
| 13 | Abnormality of the anterior horn cell (HP:0006802) | 3.71617120 |
| 14 | Birth length less than 3rd percentile (HP:0003561) | 3.64477839 |
| 15 | Right ventricular cardiomyopathy (HP:0011663) | 3.62118334 |
| 16 | Brittle hair (HP:0002299) | 3.55776287 |
| 17 | Abnormality of homocysteine metabolism (HP:0010919) | 3.18490299 |
| 18 | Homocystinuria (HP:0002156) | 3.18490299 |
| 19 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.12295663 |
| 20 | Tubulointerstitial nephritis (HP:0001970) | 3.11241736 |
| 21 | Flat capital femoral epiphysis (HP:0003370) | 3.09603156 |
| 22 | Deep philtrum (HP:0002002) | 2.90143726 |
| 23 | Infantile muscular hypotonia (HP:0008947) | 2.79928327 |
| 24 | Anhidrosis (HP:0000970) | 2.78689671 |
| 25 | Morphological abnormality of the inner ear (HP:0011390) | 2.76241471 |
| 26 | Amyloidosis (HP:0011034) | 2.75963799 |
| 27 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.72940283 |
| 28 | Conjugated hyperbilirubinemia (HP:0002908) | 2.67497120 |
| 29 | Abnormality of the preputium (HP:0100587) | 2.48609072 |
| 30 | Hypoparathyroidism (HP:0000829) | 2.46768069 |
| 31 | Abnormality of lateral ventricle (HP:0030047) | 2.46295825 |
| 32 | Long clavicles (HP:0000890) | 2.42127611 |
| 33 | Increased hepatocellular lipid droplets (HP:0006565) | 2.41914536 |
| 34 | Abnormality of midbrain morphology (HP:0002418) | 2.41717466 |
| 35 | Molar tooth sign on MRI (HP:0002419) | 2.41717466 |
| 36 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.39626882 |
| 37 | Spastic paraparesis (HP:0002313) | 2.36622844 |
| 38 | Methylmalonic acidemia (HP:0002912) | 2.35847401 |
| 39 | Testicular atrophy (HP:0000029) | 2.31922705 |
| 40 | Symptomatic seizures (HP:0011145) | 2.28753417 |
| 41 | Fine hair (HP:0002213) | 2.26994522 |
| 42 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.21589533 |
| 43 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.21280599 |
| 44 | Tetany (HP:0001281) | 2.20444635 |
| 45 | Porencephaly (HP:0002132) | 2.16383004 |
| 46 | Attenuation of retinal blood vessels (HP:0007843) | 2.15434111 |
| 47 | Erythema (HP:0010783) | 2.13671800 |
| 48 | Volvulus (HP:0002580) | 2.09546571 |
| 49 | Decreased central vision (HP:0007663) | 2.08791850 |
| 50 | Abnormality of vitamin metabolism (HP:0100508) | 2.07422340 |
| 51 | Thickened nuchal skin fold (HP:0000474) | 2.07327933 |
| 52 | Curly hair (HP:0002212) | 2.07045978 |
| 53 | Petechiae (HP:0000967) | 2.06178073 |
| 54 | Cerebral hypomyelination (HP:0006808) | 2.04999532 |
| 55 | Lipid accumulation in hepatocytes (HP:0006561) | 2.03775237 |
| 56 | Congenital stationary night blindness (HP:0007642) | 2.02826634 |
| 57 | Sensory axonal neuropathy (HP:0003390) | 2.02699717 |
| 58 | Hyperacusis (HP:0010780) | 2.02047087 |
| 59 | Methylmalonic aciduria (HP:0012120) | 2.01163761 |
| 60 | Pili torti (HP:0003777) | 11.3099806 |
| 61 | Myokymia (HP:0002411) | 1.99673774 |
| 62 | Steatorrhea (HP:0002570) | 1.99488514 |
| 63 | Horizontal nystagmus (HP:0000666) | 1.98996806 |
| 64 | CNS hypomyelination (HP:0003429) | 1.97439939 |
| 65 | Hypotrichosis (HP:0001006) | 1.95807788 |
| 66 | Syncope (HP:0001279) | 1.94672142 |
| 67 | Deep palmar crease (HP:0006191) | 1.91465403 |
| 68 | Abnormality of cochlea (HP:0000375) | 1.86998538 |
| 69 | Hypoplasia of the pons (HP:0012110) | 1.86947717 |
| 70 | Protruding tongue (HP:0010808) | 1.85844580 |
| 71 | Renal Fanconi syndrome (HP:0001994) | 1.85357887 |
| 72 | Cellular immunodeficiency (HP:0005374) | 1.84324650 |
| 73 | Chronic sinusitis (HP:0011109) | 1.81725520 |
| 74 | Respiratory difficulties (HP:0002880) | 1.80577815 |
| 75 | Abnormality of nail color (HP:0100643) | 1.77948157 |
| 76 | Elfin facies (HP:0004428) | 1.77020275 |
| 77 | Microvesicular hepatic steatosis (HP:0001414) | 1.75439648 |
| 78 | Neoplasm of the oral cavity (HP:0100649) | 1.74923271 |
| 79 | Horseshoe kidney (HP:0000085) | 1.74771911 |
| 80 | Abnormality of the epiphyses of the phalanges of the hand (HP:0005920) | 1.74578463 |
| 81 | Down-sloping shoulders (HP:0200021) | 1.74482394 |
| 82 | Hypomagnesemia (HP:0002917) | 1.72002230 |
| 83 | Coarse hair (HP:0002208) | 1.71555794 |
| 84 | Oral leukoplakia (HP:0002745) | 1.69564826 |
| 85 | Overriding aorta (HP:0002623) | 1.68621469 |
| 86 | Abnormality of the pons (HP:0007361) | 1.68420344 |
| 87 | Hypophosphatemic rickets (HP:0004912) | 1.67578481 |
| 88 | Increased number of teeth (HP:0011069) | 1.64103166 |
| 89 | Abnormality of chromosome stability (HP:0003220) | 1.62313680 |
| 90 | Pruritus (HP:0000989) | 1.61375208 |
| 91 | Smooth philtrum (HP:0000319) | 1.61021160 |
| 92 | Spontaneous abortion (HP:0005268) | 1.60367638 |
| 93 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.59869812 |
| 94 | Abnormality of renal resorption (HP:0011038) | 1.59229656 |
| 95 | Pendular nystagmus (HP:0012043) | 1.59187049 |
| 96 | Abnormality of the gastric mucosa (HP:0004295) | 1.58302128 |
| 97 | Abnormality of methionine metabolism (HP:0010901) | 1.56464695 |
| 98 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.54792853 |
| 99 | Dicarboxylic aciduria (HP:0003215) | 1.54792853 |
| 100 | J-shaped sella turcica (HP:0002680) | 1.53181912 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GRK1 | 5.37171992 |
| 2 | MAP2K3 | 5.26524431 |
| 3 | NME2 | 3.91801261 |
| 4 | CSNK1G1 | 3.23541578 |
| 5 | EPHA2 | 3.17497438 |
| 6 | EIF2AK1 | 3.16218769 |
| 7 | MAP2K4 | 3.13022479 |
| 8 | IRAK3 | 2.92892616 |
| 9 | MAP2K6 | 2.74105945 |
| 10 | IRAK2 | 2.37932700 |
| 11 | NME1 | 2.34725706 |
| 12 | CSNK1G3 | 2.30046279 |
| 13 | SRPK1 | 2.23068707 |
| 14 | CASK | 2.19066464 |
| 15 | CSNK1A1L | 2.15789948 |
| 16 | ZAK | 2.06344856 |
| 17 | PHKG1 | 1.98824301 |
| 18 | PHKG2 | 1.98824301 |
| 19 | VRK2 | 1.96853628 |
| 20 | CSNK1G2 | 1.89427827 |
| 21 | NEK2 | 1.76026366 |
| 22 | TNIK | 1.72483682 |
| 23 | TLK1 | 1.65299431 |
| 24 | MST1R | 1.62103121 |
| 25 | MST4 | 1.53471158 |
| 26 | PBK | 1.53339270 |
| 27 | EPHA3 | 1.40666656 |
| 28 | MAP3K4 | 1.38648995 |
| 29 | STK38 | 1.23140044 |
| 30 | CDK19 | 1.20190685 |
| 31 | DMPK | 1.09461823 |
| 32 | CHEK2 | 1.04282355 |
| 33 | PIM2 | 1.03359152 |
| 34 | NUAK1 | 0.99361781 |
| 35 | IRAK1 | 0.98575240 |
| 36 | VRK1 | 0.97932168 |
| 37 | MAP4K2 | 0.96857124 |
| 38 | PRKCI | 0.93936919 |
| 39 | TNK2 | 0.88198489 |
| 40 | CSNK1E | 0.87997856 |
| 41 | TAF1 | 0.87734975 |
| 42 | WNK3 | 0.86443000 |
| 43 | PRKCH | 0.84099985 |
| 44 | PRKAA1 | 0.83019376 |
| 45 | MAPK12 | 0.82098049 |
| 46 | SCYL2 | 0.75759512 |
| 47 | ERBB2 | 0.74089911 |
| 48 | ADRBK1 | 0.70398061 |
| 49 | MKNK2 | 0.62770980 |
| 50 | RAF1 | 0.60290447 |
| 51 | WEE1 | 0.59512013 |
| 52 | MAPK15 | 0.55880438 |
| 53 | AURKB | 0.55016757 |
| 54 | CDC7 | 0.54134552 |
| 55 | CDK7 | 0.51916850 |
| 56 | ACVR1B | 0.48618607 |
| 57 | MAP2K7 | 0.48529086 |
| 58 | STK3 | 0.48014080 |
| 59 | ATR | 0.47726483 |
| 60 | MAP3K6 | 0.45508826 |
| 61 | TTK | 0.41851647 |
| 62 | PRPF4B | 0.41328676 |
| 63 | NLK | 0.38735108 |
| 64 | TAOK2 | 0.37131896 |
| 65 | ATM | 0.36239853 |
| 66 | WNK1 | 0.36084311 |
| 67 | CSNK1A1 | 0.35877658 |
| 68 | CDK2 | 0.35723176 |
| 69 | LRRK2 | 0.35128179 |
| 70 | FES | 0.34864641 |
| 71 | ZAP70 | 0.34828404 |
| 72 | CSNK1D | 0.33668908 |
| 73 | CDK1 | 0.33620487 |
| 74 | PLK4 | 0.33571552 |
| 75 | AURKA | 0.33296935 |
| 76 | GSK3A | 0.32970055 |
| 77 | JAK2 | 0.29473486 |
| 78 | MAP3K10 | 0.28915564 |
| 79 | DAPK3 | 0.28585342 |
| 80 | MAP3K2 | 0.27760789 |
| 81 | NEK1 | 0.27426737 |
| 82 | CSNK2A1 | 0.27316969 |
| 83 | DAPK2 | 0.26675828 |
| 84 | HCK | 0.26616327 |
| 85 | CSNK2A2 | 0.26365532 |
| 86 | MAPK13 | 0.26045003 |
| 87 | MET | 0.26033043 |
| 88 | PDGFRB | 0.25999780 |
| 89 | BMPR1B | 0.25270272 |
| 90 | PRKD2 | 0.25065044 |
| 91 | PIM1 | 0.24865160 |
| 92 | GSK3B | 0.23962070 |
| 93 | TEC | 0.22232028 |
| 94 | MAPK14 | 0.21859242 |
| 95 | IKBKE | 0.21651305 |
| 96 | CHEK1 | 0.20831347 |
| 97 | PRKDC | 0.19924962 |
| 98 | MAP3K9 | 0.19138562 |
| 99 | RPS6KA5 | 0.18400013 |
| 100 | ADRBK2 | 0.18261814 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 3.76585943 |
| 2 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 3.38117305 |
| 3 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 3.35828720 |
| 4 | Thyroid cancer_Homo sapiens_hsa05216 | 3.03939761 |
| 5 | Phototransduction_Homo sapiens_hsa04744 | 2.95675228 |
| 6 | Ribosome_Homo sapiens_hsa03010 | 2.75534022 |
| 7 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.58210598 |
| 8 | Mismatch repair_Homo sapiens_hsa03430 | 2.37067789 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.34106072 |
| 10 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.32690092 |
| 11 | Basal transcription factors_Homo sapiens_hsa03022 | 2.31134604 |
| 12 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.28453290 |
| 13 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.17381164 |
| 14 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.10023158 |
| 15 | Spliceosome_Homo sapiens_hsa03040 | 2.04096342 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.94296489 |
| 17 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.85035338 |
| 18 | Proteasome_Homo sapiens_hsa03050 | 1.84780664 |
| 19 | Sulfur relay system_Homo sapiens_hsa04122 | 1.83913423 |
| 20 | RNA polymerase_Homo sapiens_hsa03020 | 1.83567145 |
| 21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.81096118 |
| 22 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.79922452 |
| 23 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.72876306 |
| 24 | RNA transport_Homo sapiens_hsa03013 | 1.70691141 |
| 25 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.66072394 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.64837644 |
| 27 | Bladder cancer_Homo sapiens_hsa05219 | 1.58537818 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.46550248 |
| 29 | DNA replication_Homo sapiens_hsa03030 | 1.41346880 |
| 30 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.39717686 |
| 31 | Huntingtons disease_Homo sapiens_hsa05016 | 1.30938371 |
| 32 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.29045703 |
| 33 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.24204555 |
| 34 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.19932324 |
| 35 | Parkinsons disease_Homo sapiens_hsa05012 | 1.11379951 |
| 36 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.10989747 |
| 37 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.10262887 |
| 38 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.09562769 |
| 39 | Purine metabolism_Homo sapiens_hsa00230 | 1.02449610 |
| 40 | Alzheimers disease_Homo sapiens_hsa05010 | 1.02187626 |
| 41 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.99281014 |
| 42 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.98889096 |
| 43 | Axon guidance_Homo sapiens_hsa04360 | 0.97697750 |
| 44 | Nicotine addiction_Homo sapiens_hsa05033 | 0.94679851 |
| 45 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.91669017 |
| 46 | Hepatitis C_Homo sapiens_hsa05160 | 0.89296862 |
| 47 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.88062377 |
| 48 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.87989470 |
| 49 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.85593346 |
| 50 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.84871226 |
| 51 | ABC transporters_Homo sapiens_hsa02010 | 0.84865986 |
| 52 | Lysine degradation_Homo sapiens_hsa00310 | 0.79208067 |
| 53 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.77906912 |
| 54 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.75733176 |
| 55 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.75586478 |
| 56 | Influenza A_Homo sapiens_hsa05164 | 0.74422965 |
| 57 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.73562084 |
| 58 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.70054346 |
| 59 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.68497219 |
| 60 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.67217462 |
| 61 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.64540028 |
| 62 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.62503697 |
| 63 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.62276593 |
| 64 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.61462013 |
| 65 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.60845492 |
| 66 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.60678308 |
| 67 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.57166907 |
| 68 | Colorectal cancer_Homo sapiens_hsa05210 | 0.55699574 |
| 69 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.55435830 |
| 70 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.52821048 |
| 71 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.52638206 |
| 72 | Taste transduction_Homo sapiens_hsa04742 | 0.52069986 |
| 73 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.51237577 |
| 74 | Hepatitis B_Homo sapiens_hsa05161 | 0.50788586 |
| 75 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.48164456 |
| 76 | Peroxisome_Homo sapiens_hsa04146 | 0.46520976 |
| 77 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.44231176 |
| 78 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.42413752 |
| 79 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.41871152 |
| 80 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.41657456 |
| 81 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.39032047 |
| 82 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.37846697 |
| 83 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.36551905 |
| 84 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.36119100 |
| 85 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.35849638 |
| 86 | Cell cycle_Homo sapiens_hsa04110 | 0.35566956 |
| 87 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.34277029 |
| 88 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.31751723 |
| 89 | Alcoholism_Homo sapiens_hsa05034 | 0.31369585 |
| 90 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.29186371 |
| 91 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.28847581 |
| 92 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.28377457 |
| 93 | Metabolic pathways_Homo sapiens_hsa01100 | 0.26671087 |
| 94 | Legionellosis_Homo sapiens_hsa05134 | 0.24385851 |
| 95 | Galactose metabolism_Homo sapiens_hsa00052 | 0.20309004 |
| 96 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.16053539 |
| 97 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.15499065 |
| 98 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.14914654 |
| 99 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.14711239 |
| 100 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.14599605 |

