

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of chronic inflammatory response (GO:0002676) | 5.90150812 |
| 2 | DNA deamination (GO:0045006) | 5.23721416 |
| 3 | protein neddylation (GO:0045116) | 4.98845377 |
| 4 | rRNA modification (GO:0000154) | 4.85194679 |
| 5 | rRNA methylation (GO:0031167) | 4.69763185 |
| 6 | cellular response to interleukin-15 (GO:0071350) | 4.66271904 |
| 7 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.53134230 |
| 8 | positive regulation of immune response to tumor cell (GO:0002839) | 4.41305311 |
| 9 | regulation of immune response to tumor cell (GO:0002837) | 4.41305311 |
| 10 | regulation of response to tumor cell (GO:0002834) | 4.41305311 |
| 11 | positive regulation of response to tumor cell (GO:0002836) | 4.41305311 |
| 12 | regulation of immunoglobulin secretion (GO:0051023) | 4.39249359 |
| 13 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.36715107 |
| 14 | respiratory chain complex IV assembly (GO:0008535) | 4.10089902 |
| 15 | chaperone-mediated protein transport (GO:0072321) | 3.97178424 |
| 16 | ATP synthesis coupled proton transport (GO:0015986) | 3.95528850 |
| 17 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.95528850 |
| 18 | DNA double-strand break processing (GO:0000729) | 3.92616091 |
| 19 | cytidine deamination (GO:0009972) | 3.88232290 |
| 20 | cytidine metabolic process (GO:0046087) | 3.88232290 |
| 21 | cytidine catabolic process (GO:0006216) | 3.88232290 |
| 22 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.79492801 |
| 23 | pseudouridine synthesis (GO:0001522) | 3.78363160 |
| 24 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.76220077 |
| 25 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.70334306 |
| 26 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.70334306 |
| 27 | response to interleukin-15 (GO:0070672) | 3.70325712 |
| 28 | cullin deneddylation (GO:0010388) | 3.61545349 |
| 29 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.55466442 |
| 30 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.50490913 |
| 31 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.48112620 |
| 32 | NADH dehydrogenase complex assembly (GO:0010257) | 3.48112620 |
| 33 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.48112620 |
| 34 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.46535848 |
| 35 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.40291307 |
| 36 | protein deneddylation (GO:0000338) | 3.37961343 |
| 37 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.36856101 |
| 38 | peptidyl-histidine modification (GO:0018202) | 3.36521240 |
| 39 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.36460862 |
| 40 | maturation of 5.8S rRNA (GO:0000460) | 3.34633180 |
| 41 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.34019523 |
| 42 | interferon-gamma production (GO:0032609) | 3.30878715 |
| 43 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.26575922 |
| 44 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.26575922 |
| 45 | response to redox state (GO:0051775) | 3.25915167 |
| 46 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.25850701 |
| 47 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.25850701 |
| 48 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.25850701 |
| 49 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.25561706 |
| 50 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.19776753 |
| 51 | positive regulation of osteoclast differentiation (GO:0045672) | 3.18980262 |
| 52 | protein complex biogenesis (GO:0070271) | 3.16103249 |
| 53 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.15942946 |
| 54 | regulation of T cell chemotaxis (GO:0010819) | 3.14039648 |
| 55 | positive regulation of T cell chemotaxis (GO:0010820) | 3.14039648 |
| 56 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.13697249 |
| 57 | proteasome assembly (GO:0043248) | 3.13413839 |
| 58 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.13285589 |
| 59 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.12782922 |
| 60 | negative regulation of ligase activity (GO:0051352) | 3.12782922 |
| 61 | positive regulation of T cell cytokine production (GO:0002726) | 3.12611707 |
| 62 | negative regulation of heart rate (GO:0010459) | 3.08989554 |
| 63 | rRNA catabolic process (GO:0016075) | 3.08957233 |
| 64 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.07774719 |
| 65 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.05768146 |
| 66 | mitochondrial RNA metabolic process (GO:0000959) | 3.05477807 |
| 67 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.05234658 |
| 68 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.05234658 |
| 69 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.04605583 |
| 70 | protein localization to cilium (GO:0061512) | 3.04195068 |
| 71 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.03655278 |
| 72 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.03655278 |
| 73 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.01909797 |
| 74 | hepatocyte apoptotic process (GO:0097284) | 3.01707140 |
| 75 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.99884293 |
| 76 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.99723834 |
| 77 | regulation of regulatory T cell differentiation (GO:0045589) | 2.99632668 |
| 78 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.98496709 |
| 79 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.93149049 |
| 80 | tRNA processing (GO:0008033) | 2.91226719 |
| 81 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.89690727 |
| 82 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.89268417 |
| 83 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 2.88798270 |
| 84 | positive regulation of T cell mediated immunity (GO:0002711) | 2.88618002 |
| 85 | cellular response to interferon-beta (GO:0035458) | 2.88050675 |
| 86 | positive regulation of cell killing (GO:0031343) | 2.87452507 |
| 87 | behavioral response to nicotine (GO:0035095) | 2.87421323 |
| 88 | activated T cell proliferation (GO:0050798) | 2.86287810 |
| 89 | termination of RNA polymerase III transcription (GO:0006386) | 2.84010189 |
| 90 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.84010189 |
| 91 | positive regulation of immunoglobulin production (GO:0002639) | 2.83235775 |
| 92 | tRNA metabolic process (GO:0006399) | 2.82717985 |
| 93 | signal peptide processing (GO:0006465) | 2.82186667 |
| 94 | protein-cofactor linkage (GO:0018065) | 2.79168030 |
| 95 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.78773309 |
| 96 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.78534859 |
| 97 | positive regulation of B cell mediated immunity (GO:0002714) | 2.78534859 |
| 98 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.77988266 |
| 99 | protein refolding (GO:0042026) | 2.75792595 |
| 100 | hydrogen ion transmembrane transport (GO:1902600) | 2.75001353 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.18031970 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.12851872 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.58354899 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.35369568 |
| 5 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 3.03220776 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 2.96852547 |
| 7 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.85073146 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.59556418 |
| 9 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.57056795 |
| 10 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.52027392 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.39885002 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.37153811 |
| 13 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.33788025 |
| 14 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.30087858 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.27314607 |
| 16 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.27224698 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.22242245 |
| 18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.15824427 |
| 19 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.08702984 |
| 20 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 2.03045860 |
| 21 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.98301312 |
| 22 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.95947176 |
| 23 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.95768488 |
| 24 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.87468589 |
| 25 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.87260775 |
| 26 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.85099471 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.83552123 |
| 28 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.79596565 |
| 29 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.78645576 |
| 30 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.70331210 |
| 31 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.62825488 |
| 32 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.61626768 |
| 33 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.58737256 |
| 34 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.58062501 |
| 35 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.50125659 |
| 36 | P300_19829295_ChIP-Seq_ESCs_Human | 1.48793601 |
| 37 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.46595014 |
| 38 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.46387556 |
| 39 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.45447407 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.41163117 |
| 41 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.40434238 |
| 42 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.40434238 |
| 43 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.39280749 |
| 44 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.38912240 |
| 45 | FUS_26573619_Chip-Seq_HEK293_Human | 1.37696189 |
| 46 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.36738763 |
| 47 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.35671459 |
| 48 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.33992810 |
| 49 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.31401714 |
| 50 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.30887622 |
| 51 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.30242983 |
| 52 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.29372832 |
| 53 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.27715925 |
| 54 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.27715925 |
| 55 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.26622075 |
| 56 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.24926648 |
| 57 | GATA3_26560356_Chip-Seq_TH2_Human | 1.24344518 |
| 58 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.23877152 |
| 59 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.23060168 |
| 60 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.22051671 |
| 61 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.21743985 |
| 62 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.21069882 |
| 63 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.21013911 |
| 64 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.21003506 |
| 65 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.17656288 |
| 66 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.17385890 |
| 67 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.15948862 |
| 68 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.15889025 |
| 69 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.15224344 |
| 70 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.14643495 |
| 71 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.13633545 |
| 72 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.13439730 |
| 73 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.13208221 |
| 74 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.11180740 |
| 75 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.10934860 |
| 76 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.10781417 |
| 77 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.10571795 |
| 78 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.10180130 |
| 79 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.09775043 |
| 80 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.09298837 |
| 81 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.08817308 |
| 82 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.07579989 |
| 83 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06962384 |
| 84 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.06777088 |
| 85 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.06730281 |
| 86 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.04099419 |
| 87 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.02659879 |
| 88 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.02428631 |
| 89 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.02254401 |
| 90 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.02193719 |
| 91 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.01793668 |
| 92 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 0.99807320 |
| 93 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.98807645 |
| 94 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.96646446 |
| 95 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.95651067 |
| 96 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.95298544 |
| 97 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.94808245 |
| 98 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.94326826 |
| 99 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.94186210 |
| 100 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.93860665 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001348_abnormal_lacrimal_gland | 4.54662662 |
| 2 | MP0005671_abnormal_response_to | 3.44121293 |
| 3 | MP0002163_abnormal_gland_morphology | 3.18519054 |
| 4 | MP0003646_muscle_fatigue | 3.01584394 |
| 5 | MP0000685_abnormal_immune_system | 2.94184418 |
| 6 | MP0001835_abnormal_antigen_presentation | 2.84110492 |
| 7 | MP0008872_abnormal_physiological_respon | 2.84101404 |
| 8 | MP0004147_increased_porphyrin_level | 2.75922273 |
| 9 | MP0005387_immune_system_phenotype | 2.37242440 |
| 10 | MP0001790_abnormal_immune_system | 2.37242440 |
| 11 | MP0008875_abnormal_xenobiotic_pharmacok | 2.30422853 |
| 12 | MP0009785_altered_susceptibility_to | 2.21437764 |
| 13 | MP0002102_abnormal_ear_morphology | 2.19211168 |
| 14 | MP0001873_stomach_inflammation | 2.11898251 |
| 15 | MP0004145_abnormal_muscle_electrophysio | 2.11118849 |
| 16 | MP0005379_endocrine/exocrine_gland_phen | 2.09180399 |
| 17 | MP0003436_decreased_susceptibility_to | 2.08369394 |
| 18 | MP0002006_tumorigenesis | 2.00869864 |
| 19 | MP0002876_abnormal_thyroid_physiology | 2.00826312 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 1.93444717 |
| 21 | MP0001800_abnormal_humoral_immune | 1.83740244 |
| 22 | MP0002138_abnormal_hepatobiliary_system | 1.81545485 |
| 23 | MP0002166_altered_tumor_susceptibility | 1.81323458 |
| 24 | MP0005645_abnormal_hypothalamus_physiol | 1.79205408 |
| 25 | MP0006072_abnormal_retinal_apoptosis | 1.75997233 |
| 26 | MP0004142_abnormal_muscle_tone | 1.74289764 |
| 27 | MP0005000_abnormal_immune_tolerance | 1.71214917 |
| 28 | MP0002254_reproductive_system_inflammat | 1.63344470 |
| 29 | MP0009333_abnormal_splenocyte_physiolog | 1.62428611 |
| 30 | MP0001501_abnormal_sleep_pattern | 1.59296202 |
| 31 | MP0003786_premature_aging | 1.55080408 |
| 32 | MP0003866_abnormal_defecation | 1.50262384 |
| 33 | MP0006054_spinal_hemorrhage | 1.50087619 |
| 34 | MP0003880_abnormal_central_pattern | 1.46036143 |
| 35 | MP0002272_abnormal_nervous_system | 1.41527628 |
| 36 | MP0002723_abnormal_immune_serum | 1.36813919 |
| 37 | MP0005310_abnormal_salivary_gland | 1.34165602 |
| 38 | MP0001905_abnormal_dopamine_level | 1.30347050 |
| 39 | MP0001968_abnormal_touch/_nociception | 1.27253814 |
| 40 | MP0008877_abnormal_DNA_methylation | 1.25278987 |
| 41 | MP0009046_muscle_twitch | 1.24140224 |
| 42 | MP0005084_abnormal_gallbladder_morpholo | 1.23261922 |
| 43 | MP0003724_increased_susceptibility_to | 1.22083976 |
| 44 | MP0003718_maternal_effect | 1.21768178 |
| 45 | MP0003763_abnormal_thymus_physiology | 1.21324217 |
| 46 | MP0009745_abnormal_behavioral_response | 1.20345473 |
| 47 | MP0002452_abnormal_antigen_presenting | 1.20045652 |
| 48 | MP0005551_abnormal_eye_electrophysiolog | 1.19522836 |
| 49 | MP0001440_abnormal_grooming_behavior | 1.17396265 |
| 50 | MP0009764_decreased_sensitivity_to | 1.17160360 |
| 51 | MP0004742_abnormal_vestibular_system | 1.15644111 |
| 52 | MP0001986_abnormal_taste_sensitivity | 1.14322414 |
| 53 | MP0000372_irregular_coat_pigmentation | 1.14232750 |
| 54 | MP0003186_abnormal_redox_activity | 1.12566218 |
| 55 | MP0005377_hearing/vestibular/ear_phenot | 1.11901646 |
| 56 | MP0003878_abnormal_ear_physiology | 1.11901646 |
| 57 | MP0002420_abnormal_adaptive_immunity | 1.11354086 |
| 58 | MP0010155_abnormal_intestine_physiology | 1.10757663 |
| 59 | MP0001919_abnormal_reproductive_system | 1.10739603 |
| 60 | MP0001819_abnormal_immune_cell | 1.10576582 |
| 61 | MP0001765_abnormal_ion_homeostasis | 1.09599597 |
| 62 | MP0001502_abnormal_circadian_rhythm | 1.09382090 |
| 63 | MP0003011_delayed_dark_adaptation | 1.06555630 |
| 64 | MP0005389_reproductive_system_phenotype | 1.05936072 |
| 65 | MP0001542_abnormal_bone_strength | 1.05847577 |
| 66 | MP0002735_abnormal_chemical_nociception | 1.02421642 |
| 67 | MP0005636_abnormal_mineral_homeostasis | 1.02334635 |
| 68 | MP0010386_abnormal_urinary_bladder | 1.01236660 |
| 69 | MP0005025_abnormal_response_to | 0.99730717 |
| 70 | MP0002736_abnormal_nociception_after | 0.99669891 |
| 71 | MP0001533_abnormal_skeleton_physiology | 0.99308381 |
| 72 | MP0001188_hyperpigmentation | 0.99016608 |
| 73 | MP0008438_abnormal_cutaneous_collagen | 0.98532001 |
| 74 | MP0002405_respiratory_system_inflammati | 0.97771316 |
| 75 | MP0002933_joint_inflammation | 0.96859419 |
| 76 | MP0005165_increased_susceptibility_to | 0.93050776 |
| 77 | MP0005187_abnormal_penis_morphology | 0.92714897 |
| 78 | MP0001845_abnormal_inflammatory_respons | 0.92619406 |
| 79 | MP0005646_abnormal_pituitary_gland | 0.92047217 |
| 80 | MP0000465_gastrointestinal_hemorrhage | 0.90600917 |
| 81 | MP0005253_abnormal_eye_physiology | 0.90064246 |
| 82 | MP0005085_abnormal_gallbladder_physiolo | 0.88822060 |
| 83 | MP0002160_abnormal_reproductive_system | 0.85123728 |
| 84 | MP0002751_abnormal_autonomic_nervous | 0.83370212 |
| 85 | MP0000689_abnormal_spleen_morphology | 0.82243032 |
| 86 | MP0004084_abnormal_cardiac_muscle | 0.82191568 |
| 87 | MP0004957_abnormal_blastocyst_morpholog | 0.78600374 |
| 88 | MP0001984_abnormal_olfaction | 0.77612886 |
| 89 | MP0001243_abnormal_dermal_layer | 0.76973719 |
| 90 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.76306817 |
| 91 | MP0005451_abnormal_body_composition | 0.75958926 |
| 92 | MP0000716_abnormal_immune_system | 0.73870047 |
| 93 | MP0002063_abnormal_learning/memory/cond | 0.73716077 |
| 94 | MP0004381_abnormal_hair_follicle | 0.72744144 |
| 95 | MP0002398_abnormal_bone_marrow | 0.72200974 |
| 96 | MP0000569_abnormal_digit_pigmentation | 0.71555021 |
| 97 | MP0008469_abnormal_protein_level | 0.68382498 |
| 98 | MP0004036_abnormal_muscle_relaxation | 0.68370589 |
| 99 | MP0000427_abnormal_hair_cycle | 0.68013890 |
| 100 | MP0006082_CNS_inflammation | 0.67214259 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of alanine metabolism (HP:0010916) | 4.61145450 |
| 2 | Hyperalaninemia (HP:0003348) | 4.61145450 |
| 3 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 4.61145450 |
| 4 | IgG deficiency (HP:0004315) | 4.50657565 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.20016793 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 3.97347510 |
| 7 | Increased CSF lactate (HP:0002490) | 3.97066305 |
| 8 | Mitochondrial inheritance (HP:0001427) | 3.90728236 |
| 9 | Stomatitis (HP:0010280) | 3.76889977 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.71760687 |
| 11 | Lipid accumulation in hepatocytes (HP:0006561) | 3.56381395 |
| 12 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.53087901 |
| 13 | Progressive macrocephaly (HP:0004481) | 3.51119077 |
| 14 | Acute encephalopathy (HP:0006846) | 3.46898589 |
| 15 | Increased serum lactate (HP:0002151) | 3.36988113 |
| 16 | 3-Methylglutaconic aciduria (HP:0003535) | 3.29987329 |
| 17 | Hypoproteinemia (HP:0003075) | 3.27772854 |
| 18 | Increased intramyocellular lipid droplets (HP:0012240) | 2.98160759 |
| 19 | Hepatic necrosis (HP:0002605) | 2.91440255 |
| 20 | Progressive inability to walk (HP:0002505) | 2.88768668 |
| 21 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.80246536 |
| 22 | Recurrent cutaneous fungal infections (HP:0011370) | 2.80246536 |
| 23 | Renal Fanconi syndrome (HP:0001994) | 2.75639902 |
| 24 | Congenital stationary night blindness (HP:0007642) | 2.73763414 |
| 25 | Exertional dyspnea (HP:0002875) | 2.72180971 |
| 26 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.72166364 |
| 27 | Hypoplasia of the fovea (HP:0007750) | 2.72166364 |
| 28 | Abnormality of the anterior horn cell (HP:0006802) | 2.66029956 |
| 29 | Degeneration of anterior horn cells (HP:0002398) | 2.66029956 |
| 30 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.64727164 |
| 31 | Optic disc pallor (HP:0000543) | 2.64371333 |
| 32 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.63109736 |
| 33 | Aplastic anemia (HP:0001915) | 2.62263934 |
| 34 | Abnormality of the labia minora (HP:0012880) | 2.60434952 |
| 35 | Pancreatic cysts (HP:0001737) | 2.56776905 |
| 36 | Pendular nystagmus (HP:0012043) | 2.56283525 |
| 37 | Renal cortical cysts (HP:0000803) | 2.54675015 |
| 38 | Tongue fasciculations (HP:0001308) | 2.49447632 |
| 39 | Increased IgM level (HP:0003496) | 2.42573099 |
| 40 | Agitation (HP:0000713) | 2.42202006 |
| 41 | Abnormality of the pons (HP:0007361) | 2.42194255 |
| 42 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.41193746 |
| 43 | Leukodystrophy (HP:0002415) | 2.40984777 |
| 44 | Abnormality of T cell physiology (HP:0011840) | 2.38362883 |
| 45 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.36066552 |
| 46 | Hypoplasia of the pons (HP:0012110) | 2.35311129 |
| 47 | Inability to walk (HP:0002540) | 2.34450725 |
| 48 | Abnormality of T cells (HP:0002843) | 2.34298396 |
| 49 | Constricted visual fields (HP:0001133) | 2.33880351 |
| 50 | Abnormality of T cell number (HP:0011839) | 2.33528015 |
| 51 | Increased muscle lipid content (HP:0009058) | 2.31246336 |
| 52 | Increased corneal curvature (HP:0100692) | 2.30387676 |
| 53 | Keratoconus (HP:0000563) | 2.30387676 |
| 54 | Bilateral microphthalmos (HP:0007633) | 2.28450539 |
| 55 | Abnormality of eosinophils (HP:0001879) | 2.23617855 |
| 56 | Methylmalonic acidemia (HP:0002912) | 2.22231304 |
| 57 | Lactic acidosis (HP:0003128) | 2.20683909 |
| 58 | Chorioretinal atrophy (HP:0000533) | 2.20265986 |
| 59 | B lymphocytopenia (HP:0010976) | 2.20238237 |
| 60 | Pulmonary infiltrates (HP:0002113) | 2.17427918 |
| 61 | Muscle fibrillation (HP:0010546) | 2.15723106 |
| 62 | Cerebral edema (HP:0002181) | 2.12744626 |
| 63 | Severe combined immunodeficiency (HP:0004430) | 2.09743706 |
| 64 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.07141119 |
| 65 | Fibular aplasia (HP:0002990) | 2.06081618 |
| 66 | Fatigue (HP:0012378) | 2.05585544 |
| 67 | Eosinophilia (HP:0001880) | 2.05293391 |
| 68 | Congenital, generalized hypertrichosis (HP:0004540) | 2.05243638 |
| 69 | Recurrent bronchitis (HP:0002837) | 2.03289932 |
| 70 | Type II lissencephaly (HP:0007260) | 2.02423257 |
| 71 | T lymphocytopenia (HP:0005403) | 2.01949865 |
| 72 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.00007720 |
| 73 | Joint swelling (HP:0001386) | 1.99288167 |
| 74 | Abnormality of the renal cortex (HP:0011035) | 1.99266240 |
| 75 | Carpal bone hypoplasia (HP:0001498) | 1.98641033 |
| 76 | Fair hair (HP:0002286) | 1.97750349 |
| 77 | Respiratory failure (HP:0002878) | 1.96757076 |
| 78 | Retrobulbar optic neuritis (HP:0100654) | 1.96385172 |
| 79 | Optic neuritis (HP:0100653) | 1.96385172 |
| 80 | Mutism (HP:0002300) | 1.95392627 |
| 81 | Abnormality of the fovea (HP:0000493) | 1.95062311 |
| 82 | Short tibia (HP:0005736) | 1.94896620 |
| 83 | Exercise intolerance (HP:0003546) | 1.94880392 |
| 84 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.94246432 |
| 85 | Pancytopenia (HP:0001876) | 1.89576796 |
| 86 | Methylmalonic aciduria (HP:0012120) | 1.88343367 |
| 87 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.86009484 |
| 88 | Oral leukoplakia (HP:0002745) | 1.85087074 |
| 89 | Respiratory difficulties (HP:0002880) | 1.84164394 |
| 90 | Abnormality of B cell number (HP:0010975) | 1.82623096 |
| 91 | True hermaphroditism (HP:0010459) | 1.80198319 |
| 92 | Sensory axonal neuropathy (HP:0003390) | 1.79787229 |
| 93 | Thyroiditis (HP:0100646) | 1.79078202 |
| 94 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.78465900 |
| 95 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.75893812 |
| 96 | Hypokalemic alkalosis (HP:0001949) | 1.75205102 |
| 97 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.74723717 |
| 98 | Keratoconjunctivitis (HP:0001096) | 1.74565913 |
| 99 | IgA deficiency (HP:0002720) | 1.74446388 |
| 100 | X-linked dominant inheritance (HP:0001423) | 1.73287494 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 6.44678869 |
| 2 | MST4 | 3.29540787 |
| 3 | TXK | 3.20822264 |
| 4 | BUB1 | 2.92579366 |
| 5 | TAOK3 | 2.57660043 |
| 6 | WNK4 | 2.46756146 |
| 7 | MAP3K12 | 2.42597103 |
| 8 | TLK1 | 2.40917120 |
| 9 | NEK1 | 2.02591233 |
| 10 | STK39 | 1.98722906 |
| 11 | BCR | 1.89885413 |
| 12 | SIK3 | 1.87172362 |
| 13 | EIF2AK1 | 1.85960334 |
| 14 | SRPK1 | 1.84186568 |
| 15 | PBK | 1.71079171 |
| 16 | NUAK1 | 1.60472489 |
| 17 | TRIM28 | 1.59396656 |
| 18 | OXSR1 | 1.55223004 |
| 19 | PDK2 | 1.50933560 |
| 20 | AKT3 | 1.47579915 |
| 21 | ADRBK2 | 1.45324805 |
| 22 | EIF2AK3 | 1.42301729 |
| 23 | ZAK | 1.31981410 |
| 24 | MYLK | 1.31654567 |
| 25 | GRK1 | 1.22200830 |
| 26 | CASK | 1.21526064 |
| 27 | FES | 1.14990213 |
| 28 | DYRK2 | 1.14018782 |
| 29 | BMPR2 | 1.12101055 |
| 30 | MAP3K14 | 1.09910726 |
| 31 | PIK3CG | 1.09431615 |
| 32 | JAK1 | 1.06483931 |
| 33 | EPHA3 | 1.01986042 |
| 34 | PLK3 | 1.00195883 |
| 35 | ALK | 0.99864243 |
| 36 | CDK19 | 0.93780425 |
| 37 | MAP4K2 | 0.93091455 |
| 38 | JAK3 | 0.92795931 |
| 39 | DAPK1 | 0.90045103 |
| 40 | MARK3 | 0.88816767 |
| 41 | VRK2 | 0.87497093 |
| 42 | SGK2 | 0.87140529 |
| 43 | IKBKB | 0.85042516 |
| 44 | PINK1 | 0.83339952 |
| 45 | STK38L | 0.80696799 |
| 46 | TESK1 | 0.79882297 |
| 47 | PHKG2 | 0.79302563 |
| 48 | PHKG1 | 0.79302563 |
| 49 | TAF1 | 0.77777372 |
| 50 | WNK1 | 0.76921100 |
| 51 | IKBKE | 0.74906636 |
| 52 | DYRK3 | 0.74374060 |
| 53 | EIF2AK2 | 0.72289444 |
| 54 | TIE1 | 0.71744413 |
| 55 | SCYL2 | 0.71398656 |
| 56 | MINK1 | 0.67505709 |
| 57 | CSNK1A1L | 0.66996078 |
| 58 | RPS6KA4 | 0.65109770 |
| 59 | VRK1 | 0.64535607 |
| 60 | CSNK1G3 | 0.62876385 |
| 61 | PAK3 | 0.60779964 |
| 62 | INSRR | 0.59559500 |
| 63 | TGFBR2 | 0.59399655 |
| 64 | NME1 | 0.59129092 |
| 65 | GRK6 | 0.58757617 |
| 66 | SGK223 | 0.57352471 |
| 67 | SGK494 | 0.57352471 |
| 68 | KIT | 0.55071169 |
| 69 | MAP2K6 | 0.55010349 |
| 70 | MAP4K1 | 0.53961010 |
| 71 | STK24 | 0.53703212 |
| 72 | CSNK1G2 | 0.53124230 |
| 73 | CSNK1G1 | 0.51776426 |
| 74 | MAPK12 | 0.50269678 |
| 75 | CAMK2A | 0.50093822 |
| 76 | STK4 | 0.49839976 |
| 77 | MARK1 | 0.49047378 |
| 78 | LCK | 0.48350950 |
| 79 | FRK | 0.46500294 |
| 80 | LIMK1 | 0.45402587 |
| 81 | PRKCE | 0.43337156 |
| 82 | MAPKAPK3 | 0.42919214 |
| 83 | TEC | 0.41882164 |
| 84 | SGK3 | 0.41706033 |
| 85 | PLK2 | 0.41308883 |
| 86 | MKNK2 | 0.39344941 |
| 87 | PAK4 | 0.39217062 |
| 88 | DAPK2 | 0.38869209 |
| 89 | MUSK | 0.36350349 |
| 90 | PRKCQ | 0.35538179 |
| 91 | IGF1R | 0.34737795 |
| 92 | OBSCN | 0.34518630 |
| 93 | STK16 | 0.34508228 |
| 94 | STK10 | 0.33990766 |
| 95 | SYK | 0.29819551 |
| 96 | ATR | 0.29182748 |
| 97 | DAPK3 | 0.28987717 |
| 98 | GRK5 | 0.28673527 |
| 99 | PRKCG | 0.28621036 |
| 100 | CAMK2D | 0.28458610 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.88245183 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.71482890 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.97047557 |
| 4 | Asthma_Homo sapiens_hsa05310 | 2.83670612 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.76665946 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.71202397 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.55575265 |
| 8 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.49094378 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.48905105 |
| 10 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.36725048 |
| 11 | Parkinsons disease_Homo sapiens_hsa05012 | 2.33287963 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.30195724 |
| 13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.30146210 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 1.96019153 |
| 15 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.90372575 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.89236401 |
| 17 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.88969191 |
| 18 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.87505469 |
| 19 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.85813713 |
| 20 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.80492911 |
| 21 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.76542435 |
| 22 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.69473349 |
| 23 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.67105076 |
| 24 | Alzheimers disease_Homo sapiens_hsa05010 | 1.51965602 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.46499898 |
| 26 | Huntingtons disease_Homo sapiens_hsa05016 | 1.41121199 |
| 27 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.39235033 |
| 28 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.37228563 |
| 29 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.35314333 |
| 30 | RNA degradation_Homo sapiens_hsa03018 | 1.34895971 |
| 31 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.22913502 |
| 32 | RNA transport_Homo sapiens_hsa03013 | 1.21870551 |
| 33 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.18689564 |
| 34 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.18067080 |
| 35 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.13340842 |
| 36 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.09482558 |
| 37 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.08816467 |
| 38 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.07161560 |
| 39 | Measles_Homo sapiens_hsa05162 | 1.05528420 |
| 40 | Mismatch repair_Homo sapiens_hsa03430 | 1.00016422 |
| 41 | Ribosome_Homo sapiens_hsa03010 | 0.97779927 |
| 42 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.90703295 |
| 43 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.84050663 |
| 44 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.81372401 |
| 45 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.80419131 |
| 46 | Purine metabolism_Homo sapiens_hsa00230 | 0.79707728 |
| 47 | Nicotine addiction_Homo sapiens_hsa05033 | 0.78118140 |
| 48 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.77343713 |
| 49 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.77196949 |
| 50 | Morphine addiction_Homo sapiens_hsa05032 | 0.76327287 |
| 51 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.76125865 |
| 52 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.72423181 |
| 53 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.72263468 |
| 54 | Viral myocarditis_Homo sapiens_hsa05416 | 0.71285250 |
| 55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.70193220 |
| 56 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.65291284 |
| 57 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.63889073 |
| 58 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.63853725 |
| 59 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.62165752 |
| 60 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.58073485 |
| 61 | Salivary secretion_Homo sapiens_hsa04970 | 0.54512175 |
| 62 | Olfactory transduction_Homo sapiens_hsa04740 | 0.54406674 |
| 63 | Homologous recombination_Homo sapiens_hsa03440 | 0.53737593 |
| 64 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.53611432 |
| 65 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.51149805 |
| 66 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.48996291 |
| 67 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.48278443 |
| 68 | GABAergic synapse_Homo sapiens_hsa04727 | 0.47517144 |
| 69 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.43393454 |
| 70 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.40048690 |
| 71 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.39548619 |
| 72 | Spliceosome_Homo sapiens_hsa03040 | 0.39175040 |
| 73 | Peroxisome_Homo sapiens_hsa04146 | 0.38633560 |
| 74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.35299234 |
| 75 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.34513948 |
| 76 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.34217971 |
| 77 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.33597277 |
| 78 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.33134411 |
| 79 | Renin secretion_Homo sapiens_hsa04924 | 0.32871825 |
| 80 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.32642131 |
| 81 | Insulin secretion_Homo sapiens_hsa04911 | 0.28042206 |
| 82 | Circadian entrainment_Homo sapiens_hsa04713 | 0.27201274 |
| 83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.27007260 |
| 84 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.26741151 |
| 85 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.25869033 |
| 86 | Taste transduction_Homo sapiens_hsa04742 | 0.25562141 |
| 87 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.25378654 |
| 88 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.23308593 |
| 89 | Circadian rhythm_Homo sapiens_hsa04710 | 0.22619278 |
| 90 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.22477417 |
| 91 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.21956036 |
| 92 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.21070609 |
| 93 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.20862876 |
| 94 | Retinol metabolism_Homo sapiens_hsa00830 | 0.20278594 |
| 95 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.16544321 |
| 96 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.16500972 |
| 97 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.14827730 |
| 98 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.14374422 |
| 99 | Phagosome_Homo sapiens_hsa04145 | 0.13893321 |
| 100 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.13809915 |

