

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | maturation of 5.8S rRNA (GO:0000460) | 7.72671309 |
| 2 | DNA deamination (GO:0045006) | 5.92927847 |
| 3 | nucleotide transmembrane transport (GO:1901679) | 4.90412829 |
| 4 | DNA double-strand break processing (GO:0000729) | 4.71422115 |
| 5 | proteasome assembly (GO:0043248) | 4.69683516 |
| 6 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.61192808 |
| 7 | rRNA modification (GO:0000154) | 4.56484924 |
| 8 | protein-cofactor linkage (GO:0018065) | 4.46254158 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.45907670 |
| 10 | ATP synthesis coupled proton transport (GO:0015986) | 4.45907670 |
| 11 | chaperone-mediated protein transport (GO:0072321) | 4.38655892 |
| 12 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.38109737 |
| 13 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.38109737 |
| 14 | pseudouridine synthesis (GO:0001522) | 4.33857689 |
| 15 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.33836148 |
| 16 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.31576844 |
| 17 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.22819312 |
| 18 | intracellular protein transmembrane import (GO:0044743) | 4.17377218 |
| 19 | rRNA methylation (GO:0031167) | 4.15684383 |
| 20 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.09725239 |
| 21 | protein import into peroxisome matrix (GO:0016558) | 4.08714242 |
| 22 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.05010200 |
| 23 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.98014909 |
| 24 | protein neddylation (GO:0045116) | 3.89713858 |
| 25 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.78176226 |
| 26 | termination of RNA polymerase III transcription (GO:0006386) | 3.78176226 |
| 27 | spliceosomal snRNP assembly (GO:0000387) | 3.71184201 |
| 28 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.70998226 |
| 29 | NADH dehydrogenase complex assembly (GO:0010257) | 3.70998226 |
| 30 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.70998226 |
| 31 | negative regulation of protein oligomerization (GO:0032460) | 3.69779630 |
| 32 | rRNA catabolic process (GO:0016075) | 3.67043553 |
| 33 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.61310058 |
| 34 | ribosome assembly (GO:0042255) | 3.55186081 |
| 35 | protein complex biogenesis (GO:0070271) | 3.52884898 |
| 36 | platelet dense granule organization (GO:0060155) | 3.51812194 |
| 37 | respiratory electron transport chain (GO:0022904) | 3.48324600 |
| 38 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.47778653 |
| 39 | rRNA metabolic process (GO:0016072) | 3.46973472 |
| 40 | electron transport chain (GO:0022900) | 3.43512311 |
| 41 | rRNA processing (GO:0006364) | 3.43418948 |
| 42 | mitochondrial RNA metabolic process (GO:0000959) | 3.42796562 |
| 43 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.41024476 |
| 44 | GTP biosynthetic process (GO:0006183) | 3.40754920 |
| 45 | tRNA processing (GO:0008033) | 3.38018329 |
| 46 | chromatin remodeling at centromere (GO:0031055) | 3.35045741 |
| 47 | negative regulation of telomere maintenance (GO:0032205) | 3.29833087 |
| 48 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.29100816 |
| 49 | regulation of response to tumor cell (GO:0002834) | 3.25910772 |
| 50 | positive regulation of response to tumor cell (GO:0002836) | 3.25910772 |
| 51 | positive regulation of immune response to tumor cell (GO:0002839) | 3.25910772 |
| 52 | regulation of immune response to tumor cell (GO:0002837) | 3.25910772 |
| 53 | cullin deneddylation (GO:0010388) | 3.25814591 |
| 54 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.25153887 |
| 55 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.22932370 |
| 56 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.22391464 |
| 57 | negative regulation of ligase activity (GO:0051352) | 3.22391464 |
| 58 | RNA capping (GO:0036260) | 3.21440040 |
| 59 | 7-methylguanosine RNA capping (GO:0009452) | 3.21440040 |
| 60 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.21310229 |
| 61 | intracellular protein transmembrane transport (GO:0065002) | 3.18858662 |
| 62 | transcription from mitochondrial promoter (GO:0006390) | 3.18851831 |
| 63 | CENP-A containing nucleosome assembly (GO:0034080) | 3.18543336 |
| 64 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.18541889 |
| 65 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.18541889 |
| 66 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.18541889 |
| 67 | regulation of immunoglobulin secretion (GO:0051023) | 3.17678174 |
| 68 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.15495361 |
| 69 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.15495361 |
| 70 | behavioral response to nicotine (GO:0035095) | 3.11010480 |
| 71 | inner mitochondrial membrane organization (GO:0007007) | 3.09592049 |
| 72 | tRNA metabolic process (GO:0006399) | 3.08872108 |
| 73 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.08138893 |
| 74 | cellular component biogenesis (GO:0044085) | 3.04258314 |
| 75 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.04256482 |
| 76 | isotype switching (GO:0045190) | 3.04064874 |
| 77 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.04064874 |
| 78 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.04064874 |
| 79 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.03024752 |
| 80 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.03024752 |
| 81 | respiratory chain complex IV assembly (GO:0008535) | 3.01650493 |
| 82 | ncRNA metabolic process (GO:0034660) | 3.00800620 |
| 83 | protein targeting to peroxisome (GO:0006625) | 2.99958373 |
| 84 | establishment of protein localization to peroxisome (GO:0072663) | 2.99958373 |
| 85 | protein localization to peroxisome (GO:0072662) | 2.99958373 |
| 86 | regulation of chronic inflammatory response (GO:0002676) | 2.99501881 |
| 87 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.98634344 |
| 88 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.95642295 |
| 89 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.95029853 |
| 90 | DNA damage response, detection of DNA damage (GO:0042769) | 2.93796030 |
| 91 | ncRNA processing (GO:0034470) | 2.93573707 |
| 92 | protein transmembrane transport (GO:0071806) | 2.92871823 |
| 93 | UTP biosynthetic process (GO:0006228) | 2.90028262 |
| 94 | IMP biosynthetic process (GO:0006188) | 2.90009189 |
| 95 | ribosome biogenesis (GO:0042254) | 2.89389111 |
| 96 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.88130982 |
| 97 | protein deneddylation (GO:0000338) | 2.87511478 |
| 98 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.86987038 |
| 99 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.85822119 |
| 100 | nucleobase biosynthetic process (GO:0046112) | 2.83846317 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.69827856 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.13471598 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.58121942 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.96434561 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.34743844 |
| 6 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.08700955 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.08342479 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.74012374 |
| 9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.72317770 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.65060242 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.47090067 |
| 12 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.46804177 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.39631398 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.39533831 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.39497249 |
| 16 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.38636305 |
| 17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.36830148 |
| 18 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.34833672 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.31901207 |
| 20 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.31261312 |
| 21 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.21744305 |
| 22 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.97993654 |
| 23 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.95177780 |
| 24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.94489720 |
| 25 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.91375486 |
| 26 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.90627901 |
| 27 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.90587163 |
| 28 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.86072112 |
| 29 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.85219448 |
| 30 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.84781842 |
| 31 | EWS_26573619_Chip-Seq_HEK293_Human | 1.80450607 |
| 32 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.66146581 |
| 33 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.64404657 |
| 34 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.63453956 |
| 35 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.61569696 |
| 36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.61003720 |
| 37 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.52976574 |
| 38 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.45862037 |
| 39 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.45357806 |
| 40 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.42105315 |
| 41 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.40335767 |
| 42 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.37506028 |
| 43 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.36975583 |
| 44 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.36623512 |
| 45 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.35931515 |
| 46 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.35915241 |
| 47 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.35514436 |
| 48 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.34760738 |
| 49 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.31127382 |
| 50 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.25632791 |
| 51 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.24549210 |
| 52 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.21047202 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.19983267 |
| 54 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.19983267 |
| 55 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.19731733 |
| 56 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.17574995 |
| 57 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.16196326 |
| 58 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.15566750 |
| 59 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.14943307 |
| 60 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.13616395 |
| 61 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.13352103 |
| 62 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.12013463 |
| 63 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.11963325 |
| 64 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.11456474 |
| 65 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.09651813 |
| 66 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.07681821 |
| 67 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.07565764 |
| 68 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.06497191 |
| 69 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.06497191 |
| 70 | P300_19829295_ChIP-Seq_ESCs_Human | 1.06409370 |
| 71 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.04530915 |
| 72 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.02048564 |
| 73 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.00684722 |
| 74 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.00283362 |
| 75 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.00263306 |
| 76 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.97079489 |
| 77 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.96916525 |
| 78 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.96199558 |
| 79 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.96168277 |
| 80 | FUS_26573619_Chip-Seq_HEK293_Human | 0.95141437 |
| 81 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92189585 |
| 82 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.91747367 |
| 83 | NCOR_22424771_ChIP-Seq_293T_Human | 0.89776793 |
| 84 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.85049549 |
| 85 | AR_20517297_ChIP-Seq_VCAP_Human | 0.84553748 |
| 86 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.83952613 |
| 87 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.83900718 |
| 88 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.83294935 |
| 89 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.81828537 |
| 90 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.81503196 |
| 91 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.80078866 |
| 92 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.79961992 |
| 93 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.79124162 |
| 94 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.79052194 |
| 95 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.79011504 |
| 96 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.77733338 |
| 97 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.75902656 |
| 98 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.75667459 |
| 99 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.75331343 |
| 100 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.75062617 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002254_reproductive_system_inflammat | 4.68941488 |
| 2 | MP0006082_CNS_inflammation | 3.35223961 |
| 3 | MP0001348_abnormal_lacrimal_gland | 3.28220375 |
| 4 | MP0002102_abnormal_ear_morphology | 3.22730513 |
| 5 | MP0001873_stomach_inflammation | 3.03135383 |
| 6 | MP0002876_abnormal_thyroid_physiology | 2.85216758 |
| 7 | MP0008877_abnormal_DNA_methylation | 2.76872161 |
| 8 | MP0003693_abnormal_embryo_hatching | 2.29055640 |
| 9 | MP0003718_maternal_effect | 2.28560769 |
| 10 | MP0006072_abnormal_retinal_apoptosis | 2.25664544 |
| 11 | MP0005360_urolithiasis | 2.21558470 |
| 12 | MP0008058_abnormal_DNA_repair | 2.16014738 |
| 13 | MP0002837_dystrophic_cardiac_calcinosis | 2.00365287 |
| 14 | MP0005671_abnormal_response_to | 1.98056334 |
| 15 | MP0004142_abnormal_muscle_tone | 1.96483535 |
| 16 | MP0006292_abnormal_olfactory_placode | 1.93462145 |
| 17 | MP0001188_hyperpigmentation | 1.93421517 |
| 18 | MP0008875_abnormal_xenobiotic_pharmacok | 1.92417302 |
| 19 | MP0008872_abnormal_physiological_respon | 1.76917142 |
| 20 | MP0003786_premature_aging | 1.75971318 |
| 21 | MP0000685_abnormal_immune_system | 1.75524122 |
| 22 | MP0002277_abnormal_respiratory_mucosa | 1.73380930 |
| 23 | MP0001984_abnormal_olfaction | 1.72374198 |
| 24 | MP0005645_abnormal_hypothalamus_physiol | 1.67063849 |
| 25 | MP0004957_abnormal_blastocyst_morpholog | 1.65514722 |
| 26 | MP0002736_abnormal_nociception_after | 1.63635079 |
| 27 | MP0003806_abnormal_nucleotide_metabolis | 1.63598718 |
| 28 | MP0002138_abnormal_hepatobiliary_system | 1.61272764 |
| 29 | MP0004147_increased_porphyrin_level | 1.59345363 |
| 30 | MP0009333_abnormal_splenocyte_physiolog | 1.51334559 |
| 31 | MP0004885_abnormal_endolymph | 1.47886916 |
| 32 | MP0010094_abnormal_chromosome_stability | 1.46409912 |
| 33 | MP0001919_abnormal_reproductive_system | 1.45139011 |
| 34 | MP0005084_abnormal_gallbladder_morpholo | 1.44610129 |
| 35 | MP0003195_calcinosis | 1.44393611 |
| 36 | MP0001968_abnormal_touch/_nociception | 1.40757985 |
| 37 | MP0001346_abnormal_lacrimal_gland | 1.37139997 |
| 38 | MP0009046_muscle_twitch | 1.34143401 |
| 39 | MP0003011_delayed_dark_adaptation | 1.29683887 |
| 40 | MP0005551_abnormal_eye_electrophysiolog | 1.29025792 |
| 41 | MP0003186_abnormal_redox_activity | 1.28499541 |
| 42 | MP0001835_abnormal_antigen_presentation | 1.24838837 |
| 43 | MP0002272_abnormal_nervous_system | 1.22890172 |
| 44 | MP0005389_reproductive_system_phenotype | 1.21671188 |
| 45 | MP0009785_altered_susceptibility_to | 1.21168686 |
| 46 | MP0001790_abnormal_immune_system | 1.20302713 |
| 47 | MP0005387_immune_system_phenotype | 1.20302713 |
| 48 | MP0005253_abnormal_eye_physiology | 1.18689470 |
| 49 | MP0001293_anophthalmia | 1.18681657 |
| 50 | MP0005310_abnormal_salivary_gland | 1.17446691 |
| 51 | MP0004742_abnormal_vestibular_system | 1.17319843 |
| 52 | MP0002163_abnormal_gland_morphology | 1.14563858 |
| 53 | MP0003646_muscle_fatigue | 1.11734315 |
| 54 | MP0009697_abnormal_copulation | 1.08917535 |
| 55 | MP0005379_endocrine/exocrine_gland_phen | 1.07536001 |
| 56 | MP0001501_abnormal_sleep_pattern | 1.04380180 |
| 57 | MP0006035_abnormal_mitochondrial_morpho | 1.03357615 |
| 58 | MP0004145_abnormal_muscle_electrophysio | 1.02829969 |
| 59 | MP0006276_abnormal_autonomic_nervous | 1.00625831 |
| 60 | MP0004043_abnormal_pH_regulation | 1.00303870 |
| 61 | MP0005167_abnormal_blood-brain_barrier | 0.99802040 |
| 62 | MP0006036_abnormal_mitochondrial_physio | 0.96853674 |
| 63 | MP0002938_white_spotting | 0.96565900 |
| 64 | MP0005636_abnormal_mineral_homeostasis | 0.96080324 |
| 65 | MP0002132_abnormal_respiratory_system | 0.95774635 |
| 66 | MP0001529_abnormal_vocalization | 0.94775016 |
| 67 | MP0009745_abnormal_behavioral_response | 0.91522333 |
| 68 | MP0008995_early_reproductive_senescence | 0.90568480 |
| 69 | MP0009765_abnormal_xenobiotic_induced | 0.89101480 |
| 70 | MP0001800_abnormal_humoral_immune | 0.87760344 |
| 71 | MP0000631_abnormal_neuroendocrine_gland | 0.85565207 |
| 72 | MP0001119_abnormal_female_reproductive | 0.82334920 |
| 73 | MP0002160_abnormal_reproductive_system | 0.79758090 |
| 74 | MP0002735_abnormal_chemical_nociception | 0.79548575 |
| 75 | MP0003763_abnormal_thymus_physiology | 0.77424746 |
| 76 | MP0001764_abnormal_homeostasis | 0.76295911 |
| 77 | MP0001485_abnormal_pinna_reflex | 0.76254062 |
| 78 | MP0003567_abnormal_fetal_cardiomyocyte | 0.76144335 |
| 79 | MP0008007_abnormal_cellular_replicative | 0.75067090 |
| 80 | MP0002822_catalepsy | 0.74726706 |
| 81 | MP0000372_irregular_coat_pigmentation | 0.74470352 |
| 82 | MP0004019_abnormal_vitamin_homeostasis | 0.72873629 |
| 83 | MP0001986_abnormal_taste_sensitivity | 0.71757633 |
| 84 | MP0003111_abnormal_nucleus_morphology | 0.71710973 |
| 85 | MP0005085_abnormal_gallbladder_physiolo | 0.71531961 |
| 86 | MP0001905_abnormal_dopamine_level | 0.71179481 |
| 87 | MP0009379_abnormal_foot_pigmentation | 0.70958593 |
| 88 | MP0002693_abnormal_pancreas_physiology | 0.70490912 |
| 89 | MP0002210_abnormal_sex_determination | 0.69869576 |
| 90 | MP0002148_abnormal_hypersensitivity_rea | 0.68812401 |
| 91 | MP0002405_respiratory_system_inflammati | 0.68707627 |
| 92 | MP0001663_abnormal_digestive_system | 0.68281950 |
| 93 | MP0000653_abnormal_sex_gland | 0.66654782 |
| 94 | MP0005646_abnormal_pituitary_gland | 0.66303846 |
| 95 | MP0003936_abnormal_reproductive_system | 0.64676777 |
| 96 | MP0001440_abnormal_grooming_behavior | 0.64197073 |
| 97 | MP0001486_abnormal_startle_reflex | 0.64060455 |
| 98 | MP0003787_abnormal_imprinting | 0.63619186 |
| 99 | MP0008873_increased_physiological_sensi | 0.62627908 |
| 100 | MP0003866_abnormal_defecation | 0.61896196 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.14129768 |
| 2 | Increased CSF lactate (HP:0002490) | 3.92774565 |
| 3 | Methylmalonic acidemia (HP:0002912) | 3.86115727 |
| 4 | Acute encephalopathy (HP:0006846) | 3.82121624 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.76032278 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.60671901 |
| 7 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.53240687 |
| 8 | Abnormality of alanine metabolism (HP:0010916) | 3.53240687 |
| 9 | Hyperalaninemia (HP:0003348) | 3.53240687 |
| 10 | Stomatitis (HP:0010280) | 3.50813636 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.49320985 |
| 12 | Progressive macrocephaly (HP:0004481) | 3.40383697 |
| 13 | Methylmalonic aciduria (HP:0012120) | 3.38007918 |
| 14 | Lipid accumulation in hepatocytes (HP:0006561) | 3.37133619 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.37020585 |
| 16 | Increased serum lactate (HP:0002151) | 3.17367442 |
| 17 | Hepatic necrosis (HP:0002605) | 3.12718156 |
| 18 | Brushfield spots (HP:0001088) | 3.12484329 |
| 19 | Abnormality of the labia minora (HP:0012880) | 3.06904736 |
| 20 | Abnormality of the pons (HP:0007361) | 3.05933281 |
| 21 | Hypoplasia of the pons (HP:0012110) | 3.04335518 |
| 22 | Cerebral edema (HP:0002181) | 2.87525129 |
| 23 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.80357081 |
| 24 | Lactic acidosis (HP:0003128) | 2.73153222 |
| 25 | Pendular nystagmus (HP:0012043) | 2.70658084 |
| 26 | Increased IgM level (HP:0003496) | 2.64383018 |
| 27 | 3-Methylglutaconic aciduria (HP:0003535) | 2.63413520 |
| 28 | IgG deficiency (HP:0004315) | 2.61963802 |
| 29 | Aplastic anemia (HP:0001915) | 2.61484539 |
| 30 | Pancytopenia (HP:0001876) | 2.55844863 |
| 31 | Renal Fanconi syndrome (HP:0001994) | 2.55512858 |
| 32 | Lethargy (HP:0001254) | 2.53350423 |
| 33 | Abnormality of methionine metabolism (HP:0010901) | 2.52114905 |
| 34 | Oral leukoplakia (HP:0002745) | 2.50134025 |
| 35 | Hyperglycinemia (HP:0002154) | 2.48271110 |
| 36 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.46608350 |
| 37 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.44932827 |
| 38 | Asplenia (HP:0001746) | 2.44384789 |
| 39 | Type II lissencephaly (HP:0007260) | 2.40264580 |
| 40 | Abnormality of serum amino acid levels (HP:0003112) | 2.38986655 |
| 41 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.38580669 |
| 42 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.37824463 |
| 43 | Abnormality of vitamin B metabolism (HP:0004340) | 2.35751633 |
| 44 | Hypomagnesemia (HP:0002917) | 2.33260956 |
| 45 | Abnormality of midbrain morphology (HP:0002418) | 2.32902783 |
| 46 | Molar tooth sign on MRI (HP:0002419) | 2.32902783 |
| 47 | Colon cancer (HP:0003003) | 2.32804209 |
| 48 | Female pseudohermaphroditism (HP:0010458) | 2.29789837 |
| 49 | Optic disc pallor (HP:0000543) | 2.28473683 |
| 50 | Megaloblastic anemia (HP:0001889) | 2.26950357 |
| 51 | Abnormality of homocysteine metabolism (HP:0010919) | 2.22448134 |
| 52 | Homocystinuria (HP:0002156) | 2.22448134 |
| 53 | Congenital, generalized hypertrichosis (HP:0004540) | 2.22245063 |
| 54 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.16741613 |
| 55 | Recurrent cutaneous fungal infections (HP:0011370) | 2.16741613 |
| 56 | Increased intramyocellular lipid droplets (HP:0012240) | 2.16656171 |
| 57 | Glycosuria (HP:0003076) | 2.15551184 |
| 58 | Abnormality of urine glucose concentration (HP:0011016) | 2.15551184 |
| 59 | Pancreatic cysts (HP:0001737) | 2.13928507 |
| 60 | Abnormality of magnesium homeostasis (HP:0004921) | 2.12869335 |
| 61 | Reticulocytopenia (HP:0001896) | 2.10493068 |
| 62 | Abnormality of glycine metabolism (HP:0010895) | 2.08350945 |
| 63 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.08350945 |
| 64 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.06427270 |
| 65 | Respiratory failure (HP:0002878) | 2.05949701 |
| 66 | Hyperglycinuria (HP:0003108) | 2.05509459 |
| 67 | Abnormality of B cell number (HP:0010975) | 2.05309240 |
| 68 | Abnormality of the anterior horn cell (HP:0006802) | 2.04945827 |
| 69 | Degeneration of anterior horn cells (HP:0002398) | 2.04945827 |
| 70 | True hermaphroditism (HP:0010459) | 2.03840569 |
| 71 | Exercise intolerance (HP:0003546) | 2.01412575 |
| 72 | Nephronophthisis (HP:0000090) | 2.00260731 |
| 73 | Abolished electroretinogram (ERG) (HP:0000550) | 1.97516657 |
| 74 | Horseshoe kidney (HP:0000085) | 1.95599556 |
| 75 | Meckel diverticulum (HP:0002245) | 1.94048430 |
| 76 | Constricted visual fields (HP:0001133) | 1.93854490 |
| 77 | Epiphyseal stippling (HP:0010655) | 1.91949582 |
| 78 | Exertional dyspnea (HP:0002875) | 1.91186959 |
| 79 | Abnormal drinking behavior (HP:0030082) | 1.91077327 |
| 80 | Polydipsia (HP:0001959) | 1.91077327 |
| 81 | Primary adrenal insufficiency (HP:0008207) | 1.88978582 |
| 82 | Leukodystrophy (HP:0002415) | 1.88029197 |
| 83 | Abnormality of the ileum (HP:0001549) | 1.86929120 |
| 84 | Hyperphosphaturia (HP:0003109) | 1.85169451 |
| 85 | Generalized aminoaciduria (HP:0002909) | 1.83134234 |
| 86 | Congenital stationary night blindness (HP:0007642) | 1.83106169 |
| 87 | Increased serum pyruvate (HP:0003542) | 1.82070392 |
| 88 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.81498581 |
| 89 | Dicarboxylic aciduria (HP:0003215) | 1.81498581 |
| 90 | Increased muscle lipid content (HP:0009058) | 1.81150594 |
| 91 | Neutropenia (HP:0001875) | 1.78107660 |
| 92 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.76366645 |
| 93 | Medial flaring of the eyebrow (HP:0010747) | 1.75962168 |
| 94 | Pancreatic fibrosis (HP:0100732) | 1.74382566 |
| 95 | Large for gestational age (HP:0001520) | 1.74102439 |
| 96 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.73569493 |
| 97 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.69892398 |
| 98 | Abnormality of chromosome stability (HP:0003220) | 1.69808094 |
| 99 | CNS demyelination (HP:0007305) | 1.69209201 |
| 100 | Ketoacidosis (HP:0001993) | 1.69162513 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 5.91638605 |
| 2 | PASK | 3.37463171 |
| 3 | VRK2 | 2.80555938 |
| 4 | STK16 | 2.74248830 |
| 5 | MST4 | 2.53184936 |
| 6 | BUB1 | 2.34571662 |
| 7 | ZAK | 2.29028567 |
| 8 | EIF2AK1 | 2.26842905 |
| 9 | NEK1 | 2.18679709 |
| 10 | TXK | 2.18576399 |
| 11 | SRPK1 | 2.11301360 |
| 12 | NUAK1 | 2.08233239 |
| 13 | EIF2AK3 | 2.05861420 |
| 14 | ADRBK2 | 2.05652231 |
| 15 | TRIM28 | 2.01776793 |
| 16 | WNK4 | 2.00163398 |
| 17 | VRK1 | 1.84089554 |
| 18 | PLK3 | 1.79560521 |
| 19 | GRK1 | 1.77956153 |
| 20 | TLK1 | 1.77040944 |
| 21 | PBK | 1.72850592 |
| 22 | STK39 | 1.72183627 |
| 23 | ACVR1B | 1.63013552 |
| 24 | TAF1 | 1.53139281 |
| 25 | MKNK2 | 1.53015458 |
| 26 | OXSR1 | 1.38199975 |
| 27 | BMPR1B | 1.35538174 |
| 28 | WNK3 | 1.34771711 |
| 29 | TAOK3 | 1.30767749 |
| 30 | NME1 | 1.29689664 |
| 31 | CDC7 | 1.29610704 |
| 32 | DYRK2 | 1.18441083 |
| 33 | MAP3K12 | 1.15297731 |
| 34 | MAP4K2 | 1.15129016 |
| 35 | ITK | 1.13451027 |
| 36 | BCKDK | 1.10646599 |
| 37 | MKNK1 | 1.06587707 |
| 38 | BCR | 0.99501789 |
| 39 | TNIK | 0.98098670 |
| 40 | CSNK1G2 | 0.97259136 |
| 41 | PLK4 | 0.94362128 |
| 42 | PLK1 | 0.93601049 |
| 43 | EIF2AK2 | 0.92361650 |
| 44 | CSNK1G3 | 0.91154657 |
| 45 | MAPKAPK5 | 0.90597150 |
| 46 | TTK | 0.89772450 |
| 47 | MAP2K6 | 0.88087822 |
| 48 | WEE1 | 0.83817813 |
| 49 | ALK | 0.83526370 |
| 50 | PLK2 | 0.82429969 |
| 51 | CSNK1G1 | 0.81241819 |
| 52 | TIE1 | 0.80341680 |
| 53 | CSNK1A1L | 0.76634028 |
| 54 | FRK | 0.74467948 |
| 55 | TEC | 0.73612051 |
| 56 | INSRR | 0.67875773 |
| 57 | FGR | 0.65718436 |
| 58 | IKBKB | 0.65271881 |
| 59 | PINK1 | 0.64189727 |
| 60 | PHKG1 | 0.63944398 |
| 61 | PHKG2 | 0.63944398 |
| 62 | MAP3K14 | 0.62924915 |
| 63 | PDK2 | 0.60347172 |
| 64 | ATR | 0.59170753 |
| 65 | PRKCG | 0.58753893 |
| 66 | CASK | 0.54676502 |
| 67 | PRKCQ | 0.53900322 |
| 68 | CCNB1 | 0.53441824 |
| 69 | MAP4K1 | 0.53108849 |
| 70 | RPS6KA5 | 0.49036448 |
| 71 | CSNK2A2 | 0.48121674 |
| 72 | STK38L | 0.46434070 |
| 73 | TGFBR1 | 0.46429167 |
| 74 | EPHB2 | 0.45079139 |
| 75 | CSNK2A1 | 0.45075091 |
| 76 | PAK3 | 0.44706294 |
| 77 | MAP3K11 | 0.42647969 |
| 78 | AURKA | 0.41468712 |
| 79 | NME2 | 0.40505907 |
| 80 | ATM | 0.39038409 |
| 81 | CAMKK1 | 0.38550357 |
| 82 | CSNK1E | 0.37926093 |
| 83 | CSNK1A1 | 0.37423312 |
| 84 | MAP2K7 | 0.37339363 |
| 85 | CHEK2 | 0.36507719 |
| 86 | AURKB | 0.36037611 |
| 87 | SIK3 | 0.35391275 |
| 88 | PNCK | 0.34084392 |
| 89 | FGFR1 | 0.33341859 |
| 90 | PIM2 | 0.32984861 |
| 91 | ADRBK1 | 0.32921057 |
| 92 | MAP3K4 | 0.32666723 |
| 93 | MAPK13 | 0.30469114 |
| 94 | PRKCE | 0.30350163 |
| 95 | MINK1 | 0.29540444 |
| 96 | PRKACA | 0.28007918 |
| 97 | CAMK2A | 0.27821383 |
| 98 | PRKCA | 0.27248272 |
| 99 | PRKCI | 0.25432049 |
| 100 | IKBKE | 0.25302193 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.36034926 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.50960585 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.08256849 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.96765398 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.92462628 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.84672037 |
| 7 | Ribosome_Homo sapiens_hsa03010 | 2.17416100 |
| 8 | RNA degradation_Homo sapiens_hsa03018 | 2.13428399 |
| 9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.07265207 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.00532207 |
| 11 | Mismatch repair_Homo sapiens_hsa03430 | 1.88344794 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 1.88098478 |
| 13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.71325311 |
| 14 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.69088508 |
| 15 | Homologous recombination_Homo sapiens_hsa03440 | 1.67944003 |
| 16 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.65265729 |
| 17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.64643336 |
| 18 | RNA transport_Homo sapiens_hsa03013 | 1.63767483 |
| 19 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.58653350 |
| 20 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.57564096 |
| 21 | Spliceosome_Homo sapiens_hsa03040 | 1.53705221 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.52985663 |
| 23 | DNA replication_Homo sapiens_hsa03030 | 1.48164747 |
| 24 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.47854474 |
| 25 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.43048321 |
| 26 | Allograft rejection_Homo sapiens_hsa05330 | 1.40589149 |
| 27 | Asthma_Homo sapiens_hsa05310 | 1.38198436 |
| 28 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.34487312 |
| 29 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.33568234 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.33064188 |
| 31 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.30948761 |
| 32 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.30345299 |
| 33 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.30249667 |
| 34 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.29731527 |
| 35 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.28363346 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.27262953 |
| 37 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.26837728 |
| 38 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.26064706 |
| 39 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.23074741 |
| 40 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.19028890 |
| 41 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.17795235 |
| 42 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.17772116 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 1.14599163 |
| 44 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.14457102 |
| 45 | Purine metabolism_Homo sapiens_hsa00230 | 1.13418430 |
| 46 | Sulfur relay system_Homo sapiens_hsa04122 | 1.12343843 |
| 47 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.11056001 |
| 48 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.08621870 |
| 49 | Phototransduction_Homo sapiens_hsa04744 | 1.02323009 |
| 50 | Base excision repair_Homo sapiens_hsa03410 | 1.02293940 |
| 51 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.97699695 |
| 52 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.94545169 |
| 53 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.92567877 |
| 54 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.92358149 |
| 55 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.88027443 |
| 56 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.85549800 |
| 57 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.84806070 |
| 58 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.84804323 |
| 59 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.82867507 |
| 60 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.80075349 |
| 61 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.76417235 |
| 62 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.73582824 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.72605082 |
| 64 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.71694814 |
| 65 | Retinol metabolism_Homo sapiens_hsa00830 | 0.71303230 |
| 66 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.71197783 |
| 67 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.70964928 |
| 68 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.70914709 |
| 69 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.68665692 |
| 70 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.67307972 |
| 71 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.66503804 |
| 72 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.66028917 |
| 73 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.63221561 |
| 74 | Mineral absorption_Homo sapiens_hsa04978 | 0.62047001 |
| 75 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.58158714 |
| 76 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55985872 |
| 77 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.54597985 |
| 78 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.54185579 |
| 79 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.53228725 |
| 80 | Nicotine addiction_Homo sapiens_hsa05033 | 0.52694323 |
| 81 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.51037075 |
| 82 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.50408742 |
| 83 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.50406038 |
| 84 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.47117476 |
| 85 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.46315336 |
| 86 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.46057396 |
| 87 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.45219759 |
| 88 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.44943843 |
| 89 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.43774796 |
| 90 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.42998122 |
| 91 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.40270656 |
| 92 | Carbon metabolism_Homo sapiens_hsa01200 | 0.38891494 |
| 93 | Olfactory transduction_Homo sapiens_hsa04740 | 0.32125625 |
| 94 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.31441140 |
| 95 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.30362901 |
| 96 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.29660876 |
| 97 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.29562368 |
| 98 | Legionellosis_Homo sapiens_hsa05134 | 0.26997132 |
| 99 | Morphine addiction_Homo sapiens_hsa05032 | 0.26576271 |
| 100 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.26413209 |

