

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | adaptation of signaling pathway (GO:0023058) | 8.96252277 |
| 2 | tachykinin receptor signaling pathway (GO:0007217) | 7.84225820 |
| 3 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 6.27631795 |
| 4 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 6.06576245 |
| 5 | neuron fate determination (GO:0048664) | 5.86272289 |
| 6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.47515440 |
| 7 | viral transcription (GO:0019083) | 5.19085705 |
| 8 | chaperone-mediated protein complex assembly (GO:0051131) | 5.09310562 |
| 9 | translational termination (GO:0006415) | 4.98755152 |
| 10 | ATP synthesis coupled proton transport (GO:0015986) | 4.80734598 |
| 11 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.80734598 |
| 12 | serotonin metabolic process (GO:0042428) | 4.76984761 |
| 13 | regulation of uterine smooth muscle contraction (GO:0070472) | 4.65234325 |
| 14 | dopamine biosynthetic process (GO:0042416) | 4.63689366 |
| 15 | regulation of dopamine metabolic process (GO:0042053) | 4.48933391 |
| 16 | regulation of catecholamine metabolic process (GO:0042069) | 4.48933391 |
| 17 | cotranslational protein targeting to membrane (GO:0006613) | 4.39668480 |
| 18 | protein targeting to ER (GO:0045047) | 4.36507848 |
| 19 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.33995252 |
| 20 | translational elongation (GO:0006414) | 4.26323067 |
| 21 | hyperosmotic salinity response (GO:0042538) | 4.24805319 |
| 22 | neuron fate specification (GO:0048665) | 4.20564868 |
| 23 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 4.16980886 |
| 24 | RNA destabilization (GO:0050779) | 4.15695602 |
| 25 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.09724954 |
| 26 | spinal cord association neuron differentiation (GO:0021527) | 4.03988655 |
| 27 | primary amino compound metabolic process (GO:1901160) | 4.00326930 |
| 28 | protein localization to endoplasmic reticulum (GO:0070972) | 3.99479707 |
| 29 | otic vesicle formation (GO:0030916) | 3.97892234 |
| 30 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 3.76680519 |
| 31 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 3.76680519 |
| 32 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.74721580 |
| 33 | regulation of feeding behavior (GO:0060259) | 3.71801599 |
| 34 | cellular protein complex disassembly (GO:0043624) | 3.68631053 |
| 35 | response to insecticide (GO:0017085) | 3.61201735 |
| 36 | alkaloid metabolic process (GO:0009820) | 3.55949070 |
| 37 | viral life cycle (GO:0019058) | 3.54170517 |
| 38 | behavioral response to nicotine (GO:0035095) | 3.53603423 |
| 39 | activation of MAPKKK activity (GO:0000185) | 3.52163176 |
| 40 | translational initiation (GO:0006413) | 3.45594369 |
| 41 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 3.44061210 |
| 42 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 3.44061210 |
| 43 | rRNA modification (GO:0000154) | 3.42538504 |
| 44 | catecholamine biosynthetic process (GO:0042423) | 3.41851837 |
| 45 | catechol-containing compound biosynthetic process (GO:0009713) | 3.41851837 |
| 46 | chaperone-mediated protein transport (GO:0072321) | 3.40183077 |
| 47 | ribosomal small subunit assembly (GO:0000028) | 3.39008760 |
| 48 | positive regulation of dendritic spine development (GO:0060999) | 3.37879080 |
| 49 | positive regulation of G2/M transition of mitotic cell cycle (GO:0010971) | 3.35106644 |
| 50 | positive regulation of cell cycle G2/M phase transition (GO:1902751) | 3.35106644 |
| 51 | nonmotile primary cilium assembly (GO:0035058) | 3.34500753 |
| 52 | multicellular organismal aging (GO:0010259) | 3.30358572 |
| 53 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.26208985 |
| 54 | startle response (GO:0001964) | 3.25765951 |
| 55 | negative regulation by host of viral transcription (GO:0043922) | 3.24723949 |
| 56 | signal peptide processing (GO:0006465) | 3.24585354 |
| 57 | forebrain neuron differentiation (GO:0021879) | 3.23360025 |
| 58 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.17070203 |
| 59 | protein complex disassembly (GO:0043241) | 3.13636794 |
| 60 | rRNA methylation (GO:0031167) | 3.11209095 |
| 61 | synaptic transmission, cholinergic (GO:0007271) | 3.10402947 |
| 62 | respiratory electron transport chain (GO:0022904) | 3.09508616 |
| 63 | electron transport chain (GO:0022900) | 3.02739038 |
| 64 | hindbrain development (GO:0030902) | 3.02195295 |
| 65 | proximal/distal pattern formation (GO:0009954) | 2.98952698 |
| 66 | positive regulation of response to oxidative stress (GO:1902884) | 2.98658205 |
| 67 | positive regulation of cellular response to oxidative stress (GO:1900409) | 2.98658205 |
| 68 | limb bud formation (GO:0060174) | 2.97283390 |
| 69 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.96978875 |
| 70 | maturation of SSU-rRNA (GO:0030490) | 2.96888980 |
| 71 | response to auditory stimulus (GO:0010996) | 2.96138661 |
| 72 | regulation of meiosis I (GO:0060631) | 2.90445153 |
| 73 | lateral sprouting from an epithelium (GO:0060601) | 2.87098699 |
| 74 | indole-containing compound metabolic process (GO:0042430) | 2.86878199 |
| 75 | macromolecular complex disassembly (GO:0032984) | 2.86450289 |
| 76 | indolalkylamine metabolic process (GO:0006586) | 2.86227868 |
| 77 | establishment of nucleus localization (GO:0040023) | 2.83027256 |
| 78 | cochlea development (GO:0090102) | 2.82507845 |
| 79 | positive regulation of mRNA catabolic process (GO:0061014) | 2.81804323 |
| 80 | ribosomal small subunit biogenesis (GO:0042274) | 2.81142288 |
| 81 | protein targeting to membrane (GO:0006612) | 2.78635556 |
| 82 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.76839759 |
| 83 | DNA damage response, detection of DNA damage (GO:0042769) | 2.76574861 |
| 84 | neuronal action potential propagation (GO:0019227) | 2.74035068 |
| 85 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.69655161 |
| 86 | sulfation (GO:0051923) | 2.68036532 |
| 87 | purine nucleobase biosynthetic process (GO:0009113) | 2.67245445 |
| 88 | forebrain neuron development (GO:0021884) | 2.64796584 |
| 89 | dopamine transport (GO:0015872) | 2.64762532 |
| 90 | mRNA catabolic process (GO:0006402) | 2.64171901 |
| 91 | cell differentiation in spinal cord (GO:0021515) | 2.63572366 |
| 92 | glutamate receptor signaling pathway (GO:0007215) | 2.63468421 |
| 93 | retinal ganglion cell axon guidance (GO:0031290) | 2.61516829 |
| 94 | regulation of mRNA catabolic process (GO:0061013) | 2.58677728 |
| 95 | ATP biosynthetic process (GO:0006754) | 2.58136987 |
| 96 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.57467537 |
| 97 | negative regulation of inclusion body assembly (GO:0090084) | 2.57122535 |
| 98 | neuronal action potential (GO:0019228) | 2.56815925 |
| 99 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.55817970 |
| 100 | intracellular protein transmembrane import (GO:0044743) | 2.54003549 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.88482592 |
| 2 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 4.78409272 |
| 3 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.60212694 |
| 4 | TAF15_26573619_Chip-Seq_HEK293_Human | 3.32697440 |
| 5 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.26721621 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.05352047 |
| 7 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 3.04553095 |
| 8 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.69143741 |
| 9 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.68499710 |
| 10 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.50705797 |
| 11 | FUS_26573619_Chip-Seq_HEK293_Human | 2.41163641 |
| 12 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.39971315 |
| 13 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.37667815 |
| 14 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.25726098 |
| 15 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.20028109 |
| 16 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.14163921 |
| 17 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.10440819 |
| 18 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.03362713 |
| 19 | VDR_22108803_ChIP-Seq_LS180_Human | 2.01876736 |
| 20 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.93967526 |
| 21 | EWS_26573619_Chip-Seq_HEK293_Human | 1.91924024 |
| 22 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.91149526 |
| 23 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.90346503 |
| 24 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.89871379 |
| 25 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.87837655 |
| 26 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.85791010 |
| 27 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.80376666 |
| 28 | P300_19829295_ChIP-Seq_ESCs_Human | 1.80143930 |
| 29 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.75748391 |
| 30 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.73531255 |
| 31 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.66520663 |
| 32 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.62716703 |
| 33 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.62033383 |
| 34 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.60395149 |
| 35 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.58977516 |
| 36 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.55828502 |
| 37 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.55172129 |
| 38 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.51724657 |
| 39 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.51724657 |
| 40 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.49624450 |
| 41 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.46638549 |
| 42 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.44330167 |
| 43 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.43324079 |
| 44 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.42266047 |
| 45 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.40066259 |
| 46 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.39755071 |
| 47 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.38652226 |
| 48 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.35148274 |
| 49 | AR_25329375_ChIP-Seq_VCAP_Human | 1.35139633 |
| 50 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.35062124 |
| 51 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.32519330 |
| 52 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.32519330 |
| 53 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.32519330 |
| 54 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.32462602 |
| 55 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.32315364 |
| 56 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.32111647 |
| 57 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.30554851 |
| 58 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.29971476 |
| 59 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.29461610 |
| 60 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.27173241 |
| 61 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.26946080 |
| 62 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.26806574 |
| 63 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.22252038 |
| 64 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.22252038 |
| 65 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.21961627 |
| 66 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.21961627 |
| 67 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.20831632 |
| 68 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.19164164 |
| 69 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.19036110 |
| 70 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.17902473 |
| 71 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.15415341 |
| 72 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.14230102 |
| 73 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.13930532 |
| 74 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.12497254 |
| 75 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.11721558 |
| 76 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.11278883 |
| 77 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.11152301 |
| 78 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.10875805 |
| 79 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.07735627 |
| 80 | STAT3_23295773_ChIP-Seq_U87_Human | 1.07529357 |
| 81 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.05890120 |
| 82 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.05749451 |
| 83 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.05694920 |
| 84 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.05124725 |
| 85 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.04828872 |
| 86 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.04509649 |
| 87 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.04240157 |
| 88 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.03391688 |
| 89 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.00867982 |
| 90 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.99859528 |
| 91 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.99859528 |
| 92 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.99202826 |
| 93 | TBL1_22424771_ChIP-Seq_293T_Human | 0.97999093 |
| 94 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97091037 |
| 95 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.96016123 |
| 96 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.94039230 |
| 97 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.92986245 |
| 98 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.92413511 |
| 99 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.91539280 |
| 100 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90704082 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003880_abnormal_central_pattern | 4.39649637 |
| 2 | MP0005423_abnormal_somatic_nervous | 4.33160471 |
| 3 | MP0002736_abnormal_nociception_after | 4.01412969 |
| 4 | MP0004147_increased_porphyrin_level | 3.58232253 |
| 5 | MP0009379_abnormal_foot_pigmentation | 3.55931537 |
| 6 | MP0001968_abnormal_touch/_nociception | 3.48944164 |
| 7 | MP0003136_yellow_coat_color | 3.00332951 |
| 8 | MP0002277_abnormal_respiratory_mucosa | 2.86775208 |
| 9 | MP0002653_abnormal_ependyma_morphology | 2.85133943 |
| 10 | MP0005646_abnormal_pituitary_gland | 2.68115136 |
| 11 | MP0004142_abnormal_muscle_tone | 2.04463812 |
| 12 | MP0000631_abnormal_neuroendocrine_gland | 2.01785869 |
| 13 | MP0006292_abnormal_olfactory_placode | 1.98279699 |
| 14 | MP0001529_abnormal_vocalization | 1.90668943 |
| 15 | MP0005645_abnormal_hypothalamus_physiol | 1.90377042 |
| 16 | MP0005084_abnormal_gallbladder_morpholo | 1.87308538 |
| 17 | MP0004885_abnormal_endolymph | 1.68819340 |
| 18 | MP0009745_abnormal_behavioral_response | 1.55728456 |
| 19 | MP0000569_abnormal_digit_pigmentation | 1.54776055 |
| 20 | MP0002928_abnormal_bile_duct | 1.53502913 |
| 21 | MP0005187_abnormal_penis_morphology | 1.52978100 |
| 22 | MP0004145_abnormal_muscle_electrophysio | 1.43810722 |
| 23 | MP0008058_abnormal_DNA_repair | 1.43226713 |
| 24 | MP0001486_abnormal_startle_reflex | 1.42654326 |
| 25 | MP0002735_abnormal_chemical_nociception | 1.37938936 |
| 26 | MP0002572_abnormal_emotion/affect_behav | 1.37481389 |
| 27 | MP0003121_genomic_imprinting | 1.36646281 |
| 28 | MP0001286_abnormal_eye_development | 1.36433346 |
| 29 | MP0002067_abnormal_sensory_capabilities | 1.35379206 |
| 30 | MP0004133_heterotaxia | 1.32914387 |
| 31 | MP0003315_abnormal_perineum_morphology | 1.31580297 |
| 32 | MP0005171_absent_coat_pigmentation | 1.29662567 |
| 33 | MP0000026_abnormal_inner_ear | 1.29507793 |
| 34 | MP0003123_paternal_imprinting | 1.27480865 |
| 35 | MP0000778_abnormal_nervous_system | 1.27012978 |
| 36 | MP0003787_abnormal_imprinting | 1.26583103 |
| 37 | MP0003635_abnormal_synaptic_transmissio | 1.26432766 |
| 38 | MP0001485_abnormal_pinna_reflex | 1.26318092 |
| 39 | MP0002272_abnormal_nervous_system | 1.24901753 |
| 40 | MP0000955_abnormal_spinal_cord | 1.24454021 |
| 41 | MP0002733_abnormal_thermal_nociception | 1.24260265 |
| 42 | MP0001440_abnormal_grooming_behavior | 1.24025879 |
| 43 | MP0006072_abnormal_retinal_apoptosis | 1.23998097 |
| 44 | MP0009697_abnormal_copulation | 1.23776564 |
| 45 | MP0003937_abnormal_limbs/digits/tail_de | 1.23465281 |
| 46 | MP0003938_abnormal_ear_development | 1.21188994 |
| 47 | MP0000049_abnormal_middle_ear | 1.19662109 |
| 48 | MP0005410_abnormal_fertilization | 1.16417189 |
| 49 | MP0001502_abnormal_circadian_rhythm | 1.14704221 |
| 50 | MP0002938_white_spotting | 1.14348080 |
| 51 | MP0002638_abnormal_pupillary_reflex | 1.12651476 |
| 52 | MP0005551_abnormal_eye_electrophysiolog | 1.12008956 |
| 53 | MP0002184_abnormal_innervation | 1.11967937 |
| 54 | MP0003943_abnormal_hepatobiliary_system | 1.11220014 |
| 55 | MP0002734_abnormal_mechanical_nocicepti | 1.09075787 |
| 56 | MP0002282_abnormal_trachea_morphology | 1.08129943 |
| 57 | MP0009250_abnormal_appendicular_skeleto | 1.07112870 |
| 58 | MP0000639_abnormal_adrenal_gland | 1.07060823 |
| 59 | MP0005503_abnormal_tendon_morphology | 1.06689794 |
| 60 | MP0002063_abnormal_learning/memory/cond | 1.03448293 |
| 61 | MP0006276_abnormal_autonomic_nervous | 1.03440707 |
| 62 | MP0001970_abnormal_pain_threshold | 1.02100479 |
| 63 | MP0005174_abnormal_tail_pigmentation | 1.01387972 |
| 64 | MP0001293_anophthalmia | 1.00637561 |
| 65 | MP0002138_abnormal_hepatobiliary_system | 0.99453940 |
| 66 | MP0000372_irregular_coat_pigmentation | 0.98780054 |
| 67 | MP0002697_abnormal_eye_size | 0.96798195 |
| 68 | MP0004742_abnormal_vestibular_system | 0.96681529 |
| 69 | MP0002249_abnormal_larynx_morphology | 0.96436997 |
| 70 | MP0004924_abnormal_behavior | 0.96325157 |
| 71 | MP0005386_behavior/neurological_phenoty | 0.96325157 |
| 72 | MP0000647_abnormal_sebaceous_gland | 0.95889486 |
| 73 | MP0002557_abnormal_social/conspecific_i | 0.93320820 |
| 74 | MP0002751_abnormal_autonomic_nervous | 0.93061187 |
| 75 | MP0002064_seizures | 0.91041338 |
| 76 | MP0002752_abnormal_somatic_nervous | 0.90139515 |
| 77 | MP0001905_abnormal_dopamine_level | 0.89553187 |
| 78 | MP0001963_abnormal_hearing_physiology | 0.86071693 |
| 79 | MP0004043_abnormal_pH_regulation | 0.85580737 |
| 80 | MP0003942_abnormal_urinary_system | 0.84610699 |
| 81 | MP0002152_abnormal_brain_morphology | 0.83065887 |
| 82 | MP0003119_abnormal_digestive_system | 0.82888825 |
| 83 | MP0003698_abnormal_male_reproductive | 0.81886764 |
| 84 | MP0006036_abnormal_mitochondrial_physio | 0.80390835 |
| 85 | MP0005195_abnormal_posterior_eye | 0.80036672 |
| 86 | MP0002177_abnormal_outer_ear | 0.79760387 |
| 87 | MP0003890_abnormal_embryonic-extraembry | 0.79064772 |
| 88 | MP0005220_abnormal_exocrine_pancreas | 0.77447227 |
| 89 | MP0002882_abnormal_neuron_morphology | 0.76257067 |
| 90 | MP0002069_abnormal_eating/drinking_beha | 0.75963542 |
| 91 | MP0001270_distended_abdomen | 0.74902088 |
| 92 | MP0003755_abnormal_palate_morphology | 0.74717521 |
| 93 | MP0001340_abnormal_eyelid_morphology | 0.73973152 |
| 94 | MP0004859_abnormal_synaptic_plasticity | 0.73117587 |
| 95 | MP0001188_hyperpigmentation | 0.72908611 |
| 96 | MP0000762_abnormal_tongue_morphology | 0.69478329 |
| 97 | MP0000579_abnormal_nail_morphology | 0.68732215 |
| 98 | MP0002095_abnormal_skin_pigmentation | 0.68569405 |
| 99 | MP0008995_early_reproductive_senescence | 0.68008360 |
| 100 | MP0003638_abnormal_response/metabolism_ | 0.67871502 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Septo-optic dysplasia (HP:0100842) | 4.95753970 |
| 2 | Type II lissencephaly (HP:0007260) | 4.33053533 |
| 3 | Hypothermia (HP:0002045) | 4.05465415 |
| 4 | Abnormal number of erythroid precursors (HP:0012131) | 3.90192968 |
| 5 | Diastasis recti (HP:0001540) | 3.82907077 |
| 6 | Absent septum pellucidum (HP:0001331) | 3.72972214 |
| 7 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.71701208 |
| 8 | Medial flaring of the eyebrow (HP:0010747) | 3.59969310 |
| 9 | Nephronophthisis (HP:0000090) | 3.49342178 |
| 10 | Bilateral microphthalmos (HP:0007633) | 3.45608657 |
| 11 | Focal motor seizures (HP:0011153) | 3.39893159 |
| 12 | True hermaphroditism (HP:0010459) | 3.38914361 |
| 13 | Pancreatic fibrosis (HP:0100732) | 3.25598913 |
| 14 | Oligodactyly (hands) (HP:0001180) | 3.10131653 |
| 15 | Oligodactyly (HP:0012165) | 3.07963502 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 3.05269626 |
| 17 | Abnormality of midbrain morphology (HP:0002418) | 3.05269626 |
| 18 | Abnormality of the septum pellucidum (HP:0007375) | 3.03045548 |
| 19 | Acute lymphatic leukemia (HP:0006721) | 2.99590229 |
| 20 | Optic nerve hypoplasia (HP:0000609) | 2.88690314 |
| 21 | Limb dystonia (HP:0002451) | 2.88298585 |
| 22 | Acute necrotizing encephalopathy (HP:0006965) | 2.87849191 |
| 23 | Increased hepatocellular lipid droplets (HP:0006565) | 2.79143053 |
| 24 | Anophthalmia (HP:0000528) | 2.78042964 |
| 25 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.77897177 |
| 26 | Pancreatic cysts (HP:0001737) | 2.74483167 |
| 27 | Esophageal atresia (HP:0002032) | 2.71224104 |
| 28 | Cerebellar dysplasia (HP:0007033) | 2.68690940 |
| 29 | Abnormality of the renal medulla (HP:0100957) | 2.67712722 |
| 30 | Chronic hepatic failure (HP:0100626) | 2.67171316 |
| 31 | Partial duplication of thumb phalanx (HP:0009944) | 2.66933978 |
| 32 | Growth hormone deficiency (HP:0000824) | 2.65173380 |
| 33 | Abnormality of the labia minora (HP:0012880) | 2.61391513 |
| 34 | Hypogonadotrophic hypogonadism (HP:0000044) | 2.61326856 |
| 35 | Gastrointestinal atresia (HP:0002589) | 2.60882435 |
| 36 | Renal Fanconi syndrome (HP:0001994) | 2.54132309 |
| 37 | Congenital primary aphakia (HP:0007707) | 2.52401469 |
| 38 | Gait imbalance (HP:0002141) | 2.50732960 |
| 39 | Limb hypertonia (HP:0002509) | 2.48114168 |
| 40 | Infantile muscular hypotonia (HP:0008947) | 2.45946968 |
| 41 | Fibular hypoplasia (HP:0003038) | 2.43143497 |
| 42 | Lipid accumulation in hepatocytes (HP:0006561) | 2.43097749 |
| 43 | Abnormal ciliary motility (HP:0012262) | 2.41587992 |
| 44 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.40775183 |
| 45 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.40775183 |
| 46 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.39195906 |
| 47 | Progressive macrocephaly (HP:0004481) | 2.33769564 |
| 48 | Hyperventilation (HP:0002883) | 2.32572406 |
| 49 | Abnormal drinking behavior (HP:0030082) | 2.32260795 |
| 50 | Polydipsia (HP:0001959) | 2.32260795 |
| 51 | Genital tract atresia (HP:0001827) | 2.31478064 |
| 52 | Mitochondrial inheritance (HP:0001427) | 2.26117731 |
| 53 | Macrocytic anemia (HP:0001972) | 2.25804127 |
| 54 | Vaginal atresia (HP:0000148) | 2.22996431 |
| 55 | Severe visual impairment (HP:0001141) | 2.19265529 |
| 56 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.18745847 |
| 57 | Acute encephalopathy (HP:0006846) | 2.18640076 |
| 58 | Split foot (HP:0001839) | 2.18493650 |
| 59 | Partial duplication of the phalanx of hand (HP:0009999) | 2.18221571 |
| 60 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.16984490 |
| 61 | Absent/shortened dynein arms (HP:0200106) | 2.16984490 |
| 62 | Nephrogenic diabetes insipidus (HP:0009806) | 2.14860718 |
| 63 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.14321924 |
| 64 | Depressed nasal tip (HP:0000437) | 2.13553436 |
| 65 | Sclerocornea (HP:0000647) | 2.13483989 |
| 66 | Anencephaly (HP:0002323) | 2.10007386 |
| 67 | Postaxial hand polydactyly (HP:0001162) | 2.08396533 |
| 68 | Retinal atrophy (HP:0001105) | 2.04079857 |
| 69 | Maternal diabetes (HP:0009800) | 2.03633243 |
| 70 | Hemiplegia (HP:0002301) | 2.03341270 |
| 71 | Severe muscular hypotonia (HP:0006829) | 2.01436711 |
| 72 | Cystic liver disease (HP:0006706) | 1.98201967 |
| 73 | Decreased circulating renin level (HP:0003351) | 1.96929977 |
| 74 | Lissencephaly (HP:0001339) | 1.96814767 |
| 75 | Atonic seizures (HP:0010819) | 1.96163572 |
| 76 | Increased CSF lactate (HP:0002490) | 1.94730122 |
| 77 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.94629686 |
| 78 | Attenuation of retinal blood vessels (HP:0007843) | 1.93544510 |
| 79 | Tubular atrophy (HP:0000092) | 1.92773849 |
| 80 | Reticulocytopenia (HP:0001896) | 1.90284534 |
| 81 | Slender build (HP:0001533) | 1.89676922 |
| 82 | Poor coordination (HP:0002370) | 1.88281783 |
| 83 | Short tibia (HP:0005736) | 1.86836361 |
| 84 | Intestinal atresia (HP:0011100) | 1.86769396 |
| 85 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.86570204 |
| 86 | Hemivertebrae (HP:0002937) | 1.82691332 |
| 87 | Decreased testicular size (HP:0008734) | 1.82626847 |
| 88 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.82219396 |
| 89 | Optic nerve coloboma (HP:0000588) | 1.80415881 |
| 90 | Synostosis involving the elbow (HP:0003938) | 1.79433816 |
| 91 | Humeroradial synostosis (HP:0003041) | 1.79433816 |
| 92 | Congenital hepatic fibrosis (HP:0002612) | 1.78850166 |
| 93 | Supernumerary spleens (HP:0009799) | 1.78670397 |
| 94 | Stenosis of the external auditory canal (HP:0000402) | 1.78371269 |
| 95 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.75951946 |
| 96 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.75738959 |
| 97 | Retinal dysplasia (HP:0007973) | 1.75027618 |
| 98 | Abnormality of renal resorption (HP:0011038) | 1.74588516 |
| 99 | Hemiparesis (HP:0001269) | 1.73312711 |
| 100 | Type 2 muscle fiber atrophy (HP:0003554) | 1.73191405 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PNCK | 8.14526547 |
| 2 | MAPK15 | 5.92407462 |
| 3 | TSSK6 | 3.66884229 |
| 4 | MKNK2 | 2.90824786 |
| 5 | WEE1 | 2.52869322 |
| 6 | TNIK | 2.52161849 |
| 7 | NTRK2 | 2.24023023 |
| 8 | VRK1 | 2.15392118 |
| 9 | ZAK | 2.03329686 |
| 10 | BMPR1B | 2.00589949 |
| 11 | ACVR1B | 1.95169315 |
| 12 | MKNK1 | 1.81024373 |
| 13 | VRK2 | 1.80504127 |
| 14 | MAP3K12 | 1.72378297 |
| 15 | TGFBR1 | 1.71775885 |
| 16 | CASK | 1.67069075 |
| 17 | PLK4 | 1.59754854 |
| 18 | BRSK2 | 1.56268887 |
| 19 | PRKCG | 1.51275430 |
| 20 | MAP2K4 | 1.51050589 |
| 21 | PRKD3 | 1.44045068 |
| 22 | EPHA4 | 1.42196499 |
| 23 | MUSK | 1.41957157 |
| 24 | MAPK13 | 1.38698286 |
| 25 | MAP3K4 | 1.34118911 |
| 26 | ERBB4 | 1.32466544 |
| 27 | PASK | 1.30420819 |
| 28 | PLK2 | 1.23200016 |
| 29 | CAMKK2 | 1.16541747 |
| 30 | PBK | 1.13203258 |
| 31 | WNK3 | 1.07845272 |
| 32 | PLK3 | 1.07254846 |
| 33 | CAMK1G | 1.06153002 |
| 34 | TIE1 | 1.03075874 |
| 35 | STK16 | 1.00684979 |
| 36 | CDK8 | 0.98714944 |
| 37 | TAOK1 | 0.98150200 |
| 38 | ERBB3 | 0.97465624 |
| 39 | EIF2AK3 | 0.89411390 |
| 40 | BUB1 | 0.85570829 |
| 41 | MARK1 | 0.84021528 |
| 42 | PRKCQ | 0.83600061 |
| 43 | MAP2K7 | 0.82583745 |
| 44 | ADRBK2 | 0.81500643 |
| 45 | GRK1 | 0.72664660 |
| 46 | DYRK3 | 0.72009909 |
| 47 | CAMK2B | 0.68889846 |
| 48 | PRKCE | 0.67284302 |
| 49 | MAPKAPK3 | 0.66575467 |
| 50 | TEC | 0.60234401 |
| 51 | TLK1 | 0.59584163 |
| 52 | TAOK3 | 0.58470678 |
| 53 | FGFR2 | 0.55130247 |
| 54 | EIF2AK2 | 0.54493261 |
| 55 | MAPKAPK5 | 0.53414827 |
| 56 | DYRK2 | 0.50064600 |
| 57 | YES1 | 0.47836478 |
| 58 | NTRK3 | 0.47137371 |
| 59 | TTK | 0.46038022 |
| 60 | WNK4 | 0.45768785 |
| 61 | PAK2 | 0.45711057 |
| 62 | SGK1 | 0.45318456 |
| 63 | CSNK1G2 | 0.43563152 |
| 64 | EIF2AK1 | 0.43060826 |
| 65 | STK24 | 0.42474181 |
| 66 | MAP3K6 | 0.42224820 |
| 67 | NEK9 | 0.42219633 |
| 68 | STK38L | 0.42016140 |
| 69 | PINK1 | 0.41700501 |
| 70 | IRAK1 | 0.40990834 |
| 71 | INSRR | 0.39996995 |
| 72 | CCNB1 | 0.37859449 |
| 73 | STK3 | 0.37586303 |
| 74 | PRKCZ | 0.33388108 |
| 75 | ADRBK1 | 0.32728552 |
| 76 | PTK2B | 0.32245084 |
| 77 | MAP3K5 | 0.31669730 |
| 78 | LRRK2 | 0.31149557 |
| 79 | NUAK1 | 0.31067009 |
| 80 | BRD4 | 0.30172898 |
| 81 | CDK3 | 0.30080101 |
| 82 | OXSR1 | 0.29265992 |
| 83 | NEK2 | 0.28987356 |
| 84 | CAMK1 | 0.28795827 |
| 85 | LATS2 | 0.28440669 |
| 86 | STK39 | 0.28400525 |
| 87 | CAMK2A | 0.28023747 |
| 88 | BRSK1 | 0.26450137 |
| 89 | CSNK1E | 0.25499968 |
| 90 | CAMK2D | 0.24311399 |
| 91 | CSNK1G1 | 0.22736549 |
| 92 | PRKACA | 0.22695774 |
| 93 | FGR | 0.22321286 |
| 94 | MAP2K6 | 0.21644760 |
| 95 | PLK1 | 0.20727877 |
| 96 | OBSCN | 0.20664479 |
| 97 | PHKG2 | 0.20569105 |
| 98 | PHKG1 | 0.20569105 |
| 99 | BCKDK | 0.19245695 |
| 100 | PRKG1 | 0.19131544 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.17727000 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.67496382 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.35795974 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.32403819 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 3.02435870 |
| 6 | Nicotine addiction_Homo sapiens_hsa05033 | 2.59148311 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.51400379 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.07032627 |
| 9 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.98332990 |
| 10 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.89496522 |
| 11 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.89222072 |
| 12 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.83604932 |
| 13 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.67125048 |
| 14 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.66129034 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.65770365 |
| 16 | Cocaine addiction_Homo sapiens_hsa05030 | 1.59761770 |
| 17 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.54287768 |
| 18 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.51563902 |
| 19 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.47224074 |
| 20 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.47171562 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.46816604 |
| 22 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.35389635 |
| 23 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.33541820 |
| 24 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.29276805 |
| 25 | Taste transduction_Homo sapiens_hsa04742 | 1.27384261 |
| 26 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.27015553 |
| 27 | Circadian entrainment_Homo sapiens_hsa04713 | 1.22839982 |
| 28 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.19579636 |
| 29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.16686525 |
| 30 | Spliceosome_Homo sapiens_hsa03040 | 1.15024208 |
| 31 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.12760376 |
| 32 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.11798527 |
| 33 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.09221501 |
| 34 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.07424584 |
| 35 | Phototransduction_Homo sapiens_hsa04744 | 1.06921876 |
| 36 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.99189645 |
| 37 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.98759409 |
| 38 | GABAergic synapse_Homo sapiens_hsa04727 | 0.97641061 |
| 39 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.96956514 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 0.93950070 |
| 41 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.93489527 |
| 42 | Proteasome_Homo sapiens_hsa03050 | 0.93157770 |
| 43 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.88758683 |
| 44 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.86870838 |
| 45 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.86177102 |
| 46 | Sulfur relay system_Homo sapiens_hsa04122 | 0.84866238 |
| 47 | Homologous recombination_Homo sapiens_hsa03440 | 0.84025638 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 0.83715519 |
| 49 | Olfactory transduction_Homo sapiens_hsa04740 | 0.81365361 |
| 50 | Axon guidance_Homo sapiens_hsa04360 | 0.80748933 |
| 51 | Renin secretion_Homo sapiens_hsa04924 | 0.80606189 |
| 52 | Morphine addiction_Homo sapiens_hsa05032 | 0.80123035 |
| 53 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.79879832 |
| 54 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.79522784 |
| 55 | RNA transport_Homo sapiens_hsa03013 | 0.77436511 |
| 56 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.76148658 |
| 57 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.75438512 |
| 58 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.74953005 |
| 59 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.73943338 |
| 60 | Basal transcription factors_Homo sapiens_hsa03022 | 0.73679741 |
| 61 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.73594299 |
| 62 | Long-term potentiation_Homo sapiens_hsa04720 | 0.72796128 |
| 63 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.72364088 |
| 64 | Circadian rhythm_Homo sapiens_hsa04710 | 0.72096595 |
| 65 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.67153956 |
| 66 | Long-term depression_Homo sapiens_hsa04730 | 0.64493525 |
| 67 | Base excision repair_Homo sapiens_hsa03410 | 0.64424223 |
| 68 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.63812829 |
| 69 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.58850961 |
| 70 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.57584158 |
| 71 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.57457887 |
| 72 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.56089014 |
| 73 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54822825 |
| 74 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.54673985 |
| 75 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.53573986 |
| 76 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.51374239 |
| 77 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.50904830 |
| 78 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.50808691 |
| 79 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.50389134 |
| 80 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.49283395 |
| 81 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.48416574 |
| 82 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.48153858 |
| 83 | Metabolic pathways_Homo sapiens_hsa01100 | 0.47652588 |
| 84 | Retinol metabolism_Homo sapiens_hsa00830 | 0.46853358 |
| 85 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.45370515 |
| 86 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.44674442 |
| 87 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.44313587 |
| 88 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.42897677 |
| 89 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.42423101 |
| 90 | Gap junction_Homo sapiens_hsa04540 | 0.41101000 |
| 91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40951923 |
| 92 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.40673252 |
| 93 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.39817434 |
| 94 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.38162701 |
| 95 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.37633776 |
| 96 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.35092306 |
| 97 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.34571609 |
| 98 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.34195486 |
| 99 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.32491530 |
| 100 | Histidine metabolism_Homo sapiens_hsa00340 | 0.32359838 |

