

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of immunoglobulin secretion (GO:0051023) | 9.92030567 |
| 2 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 9.59259162 |
| 3 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 8.30843766 |
| 4 | regulation of regulatory T cell differentiation (GO:0045589) | 6.15905706 |
| 5 | negative regulation of B cell apoptotic process (GO:0002903) | 6.08429857 |
| 6 | regulation of isotype switching to IgG isotypes (GO:0048302) | 5.97904213 |
| 7 | positive regulation of interleukin-17 production (GO:0032740) | 5.93952492 |
| 8 | tachykinin receptor signaling pathway (GO:0007217) | 5.34116958 |
| 9 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 5.30465199 |
| 10 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 5.30465199 |
| 11 | isotype switching (GO:0045190) | 5.30465199 |
| 12 | positive regulation of isotype switching (GO:0045830) | 4.96947880 |
| 13 | positive regulation of DNA recombination (GO:0045911) | 4.79199995 |
| 14 | rRNA modification (GO:0000154) | 4.76568441 |
| 15 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 4.73135043 |
| 16 | DNA deamination (GO:0045006) | 4.55143201 |
| 17 | positive regulation of T cell migration (GO:2000406) | 4.39414013 |
| 18 | cullin deneddylation (GO:0010388) | 4.39250205 |
| 19 | rRNA methylation (GO:0031167) | 4.22980384 |
| 20 | ribosome biogenesis (GO:0042254) | 4.22940616 |
| 21 | regulation of B cell apoptotic process (GO:0002902) | 4.20212354 |
| 22 | positive regulation of activated T cell proliferation (GO:0042104) | 4.06896529 |
| 23 | proteasome assembly (GO:0043248) | 4.05682705 |
| 24 | positive regulation of protein homodimerization activity (GO:0090073) | 4.05004547 |
| 25 | protein deneddylation (GO:0000338) | 4.02561837 |
| 26 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.89818444 |
| 27 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.89818444 |
| 28 | synapsis (GO:0007129) | 3.82732164 |
| 29 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 3.71140722 |
| 30 | regulation of T cell migration (GO:2000404) | 3.68088578 |
| 31 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.63863128 |
| 32 | interferon-gamma production (GO:0032609) | 3.58094430 |
| 33 | GTP biosynthetic process (GO:0006183) | 3.57784545 |
| 34 | somatic diversification of immunoglobulins (GO:0016445) | 3.57387984 |
| 35 | positive regulation of lymphocyte migration (GO:2000403) | 3.54356824 |
| 36 | regulation of uterine smooth muscle contraction (GO:0070472) | 3.50877874 |
| 37 | chaperone-mediated protein transport (GO:0072321) | 3.50784799 |
| 38 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.45395736 |
| 39 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.40701032 |
| 40 | regulation of immunoglobulin production (GO:0002637) | 3.39035850 |
| 41 | positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) | 3.38635584 |
| 42 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.25668680 |
| 43 | regulation of memory T cell differentiation (GO:0043380) | 3.24017018 |
| 44 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.23796223 |
| 45 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.22183704 |
| 46 | negative regulation of ligase activity (GO:0051352) | 3.22183704 |
| 47 | pseudouridine synthesis (GO:0001522) | 3.21675886 |
| 48 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.18295168 |
| 49 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 3.17012292 |
| 50 | regulation of interleukin-17 production (GO:0032660) | 3.14644241 |
| 51 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.12846667 |
| 52 | ATP synthesis coupled proton transport (GO:0015986) | 3.12846667 |
| 53 | protein targeting to mitochondrion (GO:0006626) | 3.12653365 |
| 54 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.11175129 |
| 55 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.08647459 |
| 56 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.08647459 |
| 57 | tolerance induction (GO:0002507) | 3.06979992 |
| 58 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.05967744 |
| 59 | positive regulation of B cell mediated immunity (GO:0002714) | 3.05967744 |
| 60 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.05757925 |
| 61 | regulation of mitochondrial translation (GO:0070129) | 3.05059064 |
| 62 | signal peptide processing (GO:0006465) | 3.04524644 |
| 63 | B cell activation involved in immune response (GO:0002312) | 3.04360241 |
| 64 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 3.03027039 |
| 65 | ribosomal small subunit assembly (GO:0000028) | 3.00654294 |
| 66 | positive regulation of defense response to virus by host (GO:0002230) | 2.99561395 |
| 67 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.97106958 |
| 68 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.97106958 |
| 69 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.97106958 |
| 70 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.96750575 |
| 71 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.96750575 |
| 72 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 2.96486409 |
| 73 | UTP biosynthetic process (GO:0006228) | 2.96385693 |
| 74 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.94749283 |
| 75 | peptidyl-histidine modification (GO:0018202) | 2.93852057 |
| 76 | rRNA processing (GO:0006364) | 2.90990716 |
| 77 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.90530524 |
| 78 | regulation of isotype switching (GO:0045191) | 2.86173346 |
| 79 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.86112100 |
| 80 | rRNA metabolic process (GO:0016072) | 2.84873191 |
| 81 | establishment of protein localization to mitochondrion (GO:0072655) | 2.83710067 |
| 82 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.82673352 |
| 83 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.82673352 |
| 84 | regulation of tyrosine phosphorylation of STAT protein (GO:0042509) | 2.79948416 |
| 85 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.79871830 |
| 86 | cellular component biogenesis (GO:0044085) | 2.79555809 |
| 87 | pyrimidine ribonucleotide biosynthetic process (GO:0009220) | 2.78379144 |
| 88 | ribosomal large subunit biogenesis (GO:0042273) | 2.77652948 |
| 89 | protein localization to mitochondrion (GO:0070585) | 2.77584617 |
| 90 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.76538015 |
| 91 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.73703146 |
| 92 | termination of RNA polymerase III transcription (GO:0006386) | 2.73703146 |
| 93 | pyrimidine nucleotide biosynthetic process (GO:0006221) | 2.72533231 |
| 94 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.71601968 |
| 95 | nucleobase biosynthetic process (GO:0046112) | 2.69985454 |
| 96 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.69236109 |
| 97 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.69236109 |
| 98 | inner mitochondrial membrane organization (GO:0007007) | 2.68917372 |
| 99 | CTP metabolic process (GO:0046036) | 2.68771462 |
| 100 | CTP biosynthetic process (GO:0006241) | 2.68771462 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.93372395 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.76684838 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.52182101 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.08607600 |
| 5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.18922526 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.16168615 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.11422978 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.95827155 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.70373977 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.68498484 |
| 11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.65510250 |
| 12 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.59568000 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.36723046 |
| 14 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.35728270 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.26486963 |
| 16 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.24262602 |
| 17 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.23345993 |
| 18 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.20300024 |
| 19 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.03581002 |
| 20 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.02445759 |
| 21 | EWS_26573619_Chip-Seq_HEK293_Human | 1.98957035 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.96474234 |
| 23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.93415696 |
| 24 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.90206674 |
| 25 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.89358961 |
| 26 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.87254285 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.81245027 |
| 28 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.80324579 |
| 29 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.77190677 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.71655101 |
| 31 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.71279630 |
| 32 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.70435702 |
| 33 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.62725660 |
| 34 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.62398835 |
| 35 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.61742268 |
| 36 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.59947435 |
| 37 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.59752315 |
| 38 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.57544593 |
| 39 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.56610303 |
| 40 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.51580291 |
| 41 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.50184726 |
| 42 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.45708838 |
| 43 | GATA3_26560356_Chip-Seq_TH2_Human | 1.42678041 |
| 44 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.36074599 |
| 45 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.35886295 |
| 46 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.33872243 |
| 47 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.33720327 |
| 48 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.32997081 |
| 49 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.32029544 |
| 50 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.31350600 |
| 51 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.30438583 |
| 52 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.30021119 |
| 53 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.28857369 |
| 54 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.27292635 |
| 55 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.27144407 |
| 56 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20596894 |
| 57 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.19563225 |
| 58 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.19030008 |
| 59 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.18597235 |
| 60 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.17324193 |
| 61 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.15527229 |
| 62 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.12313916 |
| 63 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.12165448 |
| 64 | MYB_26560356_Chip-Seq_TH2_Human | 1.11924826 |
| 65 | NCOR_22424771_ChIP-Seq_293T_Human | 1.10871749 |
| 66 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.08751408 |
| 67 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.08168208 |
| 68 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.05172076 |
| 69 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.05166822 |
| 70 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.05145623 |
| 71 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.04887312 |
| 72 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.04429524 |
| 73 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.03914614 |
| 74 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.03397164 |
| 75 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.02601263 |
| 76 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.01506228 |
| 77 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.01340338 |
| 78 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.00536133 |
| 79 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.00132307 |
| 80 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.99889011 |
| 81 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.98898692 |
| 82 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.98898692 |
| 83 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.98391714 |
| 84 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.97960953 |
| 85 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.97835637 |
| 86 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.95253135 |
| 87 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.94110813 |
| 88 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.94110813 |
| 89 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.93043286 |
| 90 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.93041627 |
| 91 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.92659710 |
| 92 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.92156380 |
| 93 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.92109611 |
| 94 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.91557610 |
| 95 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.91554033 |
| 96 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.91191756 |
| 97 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.89973301 |
| 98 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.89214188 |
| 99 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.88146184 |
| 100 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.87253382 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000604_amyloidosis | 5.24662550 |
| 2 | MP0003300_gastrointestinal_ulcer | 4.54345304 |
| 3 | MP0001835_abnormal_antigen_presentation | 4.38103067 |
| 4 | MP0000465_gastrointestinal_hemorrhage | 4.01486504 |
| 5 | MP0003329_amyloid_beta_deposits | 3.66292009 |
| 6 | MP0005671_abnormal_response_to | 3.12775116 |
| 7 | MP0003806_abnormal_nucleotide_metabolis | 3.08914124 |
| 8 | MP0002102_abnormal_ear_morphology | 2.86184140 |
| 9 | MP0001853_heart_inflammation | 2.76108273 |
| 10 | MP0003786_premature_aging | 2.74182080 |
| 11 | MP0000685_abnormal_immune_system | 2.50537923 |
| 12 | MP0003763_abnormal_thymus_physiology | 2.28632062 |
| 13 | MP0004885_abnormal_endolymph | 2.10032775 |
| 14 | MP0002876_abnormal_thyroid_physiology | 1.94448231 |
| 15 | MP0003718_maternal_effect | 1.92518766 |
| 16 | MP0002736_abnormal_nociception_after | 1.83540253 |
| 17 | MP0000372_irregular_coat_pigmentation | 1.78399934 |
| 18 | MP0008877_abnormal_DNA_methylation | 1.73651390 |
| 19 | MP0008875_abnormal_xenobiotic_pharmacok | 1.69367948 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 1.68906938 |
| 21 | MP0001790_abnormal_immune_system | 1.67778671 |
| 22 | MP0005387_immune_system_phenotype | 1.67778671 |
| 23 | MP0004782_abnormal_surfactant_physiolog | 1.58707330 |
| 24 | MP0009840_abnormal_foam_cell | 1.53951532 |
| 25 | MP0009333_abnormal_splenocyte_physiolog | 1.53427828 |
| 26 | MP0008789_abnormal_olfactory_epithelium | 1.53244905 |
| 27 | MP0003191_abnormal_cellular_cholesterol | 1.50567747 |
| 28 | MP0010094_abnormal_chromosome_stability | 1.46084728 |
| 29 | MP0001800_abnormal_humoral_immune | 1.42234519 |
| 30 | MP0006292_abnormal_olfactory_placode | 1.42085995 |
| 31 | MP0002405_respiratory_system_inflammati | 1.41737297 |
| 32 | MP0002837_dystrophic_cardiac_calcinosis | 1.40365587 |
| 33 | MP0001968_abnormal_touch/_nociception | 1.36860767 |
| 34 | MP0002234_abnormal_pharynx_morphology | 1.32068671 |
| 35 | MP0001873_stomach_inflammation | 1.30579826 |
| 36 | MP0008007_abnormal_cellular_replicative | 1.30308857 |
| 37 | MP0009697_abnormal_copulation | 1.30185866 |
| 38 | MP0006036_abnormal_mitochondrial_physio | 1.30102309 |
| 39 | MP0003878_abnormal_ear_physiology | 1.29429607 |
| 40 | MP0005377_hearing/vestibular/ear_phenot | 1.29429607 |
| 41 | MP0002138_abnormal_hepatobiliary_system | 1.26773424 |
| 42 | MP0005000_abnormal_immune_tolerance | 1.25712469 |
| 43 | MP0003693_abnormal_embryo_hatching | 1.25185313 |
| 44 | MP0002723_abnormal_immune_serum | 1.19590155 |
| 45 | MP0005025_abnormal_response_to | 1.17569632 |
| 46 | MP0008872_abnormal_physiological_respon | 1.17387522 |
| 47 | MP0004957_abnormal_blastocyst_morpholog | 1.16482526 |
| 48 | MP0003195_calcinosis | 1.15866019 |
| 49 | MP0003011_delayed_dark_adaptation | 1.15486774 |
| 50 | MP0001348_abnormal_lacrimal_gland | 1.11381114 |
| 51 | MP0005645_abnormal_hypothalamus_physiol | 1.10301146 |
| 52 | MP0006072_abnormal_retinal_apoptosis | 1.09504629 |
| 53 | MP0000703_abnormal_thymus_morphology | 1.03261140 |
| 54 | MP0002420_abnormal_adaptive_immunity | 1.00543162 |
| 55 | MP0001819_abnormal_immune_cell | 0.99720276 |
| 56 | MP0002398_abnormal_bone_marrow | 0.99559961 |
| 57 | MP0001529_abnormal_vocalization | 0.98981615 |
| 58 | MP0002277_abnormal_respiratory_mucosa | 0.98980100 |
| 59 | MP0003252_abnormal_bile_duct | 0.98508356 |
| 60 | MP0000689_abnormal_spleen_morphology | 0.98498903 |
| 61 | MP0002163_abnormal_gland_morphology | 0.98233902 |
| 62 | MP0002722_abnormal_immune_system | 0.97952247 |
| 63 | MP0000049_abnormal_middle_ear | 0.97720869 |
| 64 | MP0001119_abnormal_female_reproductive | 0.96365235 |
| 65 | MP0004145_abnormal_muscle_electrophysio | 0.94297028 |
| 66 | MP0005360_urolithiasis | 0.93069805 |
| 67 | MP0002452_abnormal_antigen_presenting | 0.91045243 |
| 68 | MP0008057_abnormal_DNA_replication | 0.89670121 |
| 69 | MP0003866_abnormal_defecation | 0.88620423 |
| 70 | MP0005410_abnormal_fertilization | 0.86598159 |
| 71 | MP0010155_abnormal_intestine_physiology | 0.86099419 |
| 72 | MP0001881_abnormal_mammary_gland | 0.85432410 |
| 73 | MP0002796_impaired_skin_barrier | 0.85076798 |
| 74 | MP0003724_increased_susceptibility_to | 0.84882797 |
| 75 | MP0005499_abnormal_olfactory_system | 0.84414251 |
| 76 | MP0005394_taste/olfaction_phenotype | 0.84414251 |
| 77 | MP0008058_abnormal_DNA_repair | 0.84095715 |
| 78 | MP0002210_abnormal_sex_determination | 0.84002340 |
| 79 | MP0000716_abnormal_immune_system | 0.83940785 |
| 80 | MP0009785_altered_susceptibility_to | 0.83776810 |
| 81 | MP0001485_abnormal_pinna_reflex | 0.81206127 |
| 82 | MP0009278_abnormal_bone_marrow | 0.79854180 |
| 83 | MP0002429_abnormal_blood_cell | 0.73962239 |
| 84 | MP0003941_abnormal_skin_development | 0.73799264 |
| 85 | MP0004147_increased_porphyrin_level | 0.73575691 |
| 86 | MP0003646_muscle_fatigue | 0.72591936 |
| 87 | MP0009379_abnormal_foot_pigmentation | 0.72040124 |
| 88 | MP0004043_abnormal_pH_regulation | 0.71211718 |
| 89 | MP0005646_abnormal_pituitary_gland | 0.70924157 |
| 90 | MP0001845_abnormal_inflammatory_respons | 0.69779081 |
| 91 | MP0001501_abnormal_sleep_pattern | 0.69538899 |
| 92 | MP0010329_abnormal_lipoprotein_level | 0.69455982 |
| 93 | MP0003077_abnormal_cell_cycle | 0.67966014 |
| 94 | MP0001929_abnormal_gametogenesis | 0.67762307 |
| 95 | MP0001346_abnormal_lacrimal_gland | 0.66764180 |
| 96 | MP0006035_abnormal_mitochondrial_morpho | 0.65456342 |
| 97 | MP0005551_abnormal_eye_electrophysiolog | 0.65445209 |
| 98 | MP0002693_abnormal_pancreas_physiology | 0.63442271 |
| 99 | MP0002229_neurodegeneration | 0.63319399 |
| 100 | MP0000631_abnormal_neuroendocrine_gland | 0.60361048 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 9.72782943 |
| 2 | Increased IgM level (HP:0003496) | 5.78379554 |
| 3 | IgG deficiency (HP:0004315) | 5.50489727 |
| 4 | IgA deficiency (HP:0002720) | 4.89701373 |
| 5 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.23815638 |
| 6 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.23216666 |
| 7 | Abnormality of T cell physiology (HP:0011840) | 4.16997746 |
| 8 | 3-Methylglutaconic aciduria (HP:0003535) | 3.86728513 |
| 9 | Hypoplasia of the pons (HP:0012110) | 3.56396909 |
| 10 | Abnormality of T cells (HP:0002843) | 3.34802996 |
| 11 | Poor head control (HP:0002421) | 3.32465794 |
| 12 | Colon cancer (HP:0003003) | 3.29640986 |
| 13 | Testicular atrophy (HP:0000029) | 3.26543800 |
| 14 | Abnormal number of erythroid precursors (HP:0012131) | 3.25577214 |
| 15 | Abnormality of the pons (HP:0007361) | 3.24336669 |
| 16 | Limb dystonia (HP:0002451) | 3.22005935 |
| 17 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.05656673 |
| 18 | Parakeratosis (HP:0001036) | 2.98290822 |
| 19 | Dysphonia (HP:0001618) | 2.96792073 |
| 20 | Dyschromatopsia (HP:0007641) | 2.86778679 |
| 21 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.84120311 |
| 22 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.82614763 |
| 23 | Acute necrotizing encephalopathy (HP:0006965) | 2.80010255 |
| 24 | Lipid accumulation in hepatocytes (HP:0006561) | 2.78183890 |
| 25 | Abnormality of incisor morphology (HP:0011063) | 2.68690034 |
| 26 | Type 2 muscle fiber atrophy (HP:0003554) | 2.66805151 |
| 27 | Erythroderma (HP:0001019) | 2.64160254 |
| 28 | IgM deficiency (HP:0002850) | 2.62508662 |
| 29 | Pancytopenia (HP:0001876) | 2.62297508 |
| 30 | Bile duct proliferation (HP:0001408) | 2.61161534 |
| 31 | Abnormal biliary tract physiology (HP:0012439) | 2.61161534 |
| 32 | Hypergammaglobulinemia (HP:0010702) | 2.49445040 |
| 33 | Sensory axonal neuropathy (HP:0003390) | 2.48390486 |
| 34 | Acute encephalopathy (HP:0006846) | 2.45746298 |
| 35 | Increased CSF lactate (HP:0002490) | 2.43516477 |
| 36 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.43206265 |
| 37 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.42828633 |
| 38 | Oral leukoplakia (HP:0002745) | 2.41368713 |
| 39 | Abnormality of the prostate (HP:0008775) | 2.39913556 |
| 40 | B lymphocytopenia (HP:0010976) | 2.38917361 |
| 41 | Mitochondrial inheritance (HP:0001427) | 2.38312989 |
| 42 | Severe combined immunodeficiency (HP:0004430) | 2.34709953 |
| 43 | Duplicated collecting system (HP:0000081) | 2.34594036 |
| 44 | Abnormality of B cell number (HP:0010975) | 2.33547294 |
| 45 | Neutropenia (HP:0001875) | 2.32158409 |
| 46 | Hyperglycinuria (HP:0003108) | 2.29816475 |
| 47 | Prostate neoplasm (HP:0100787) | 2.28410541 |
| 48 | Multiple enchondromatosis (HP:0005701) | 2.27168493 |
| 49 | Alopecia of scalp (HP:0002293) | 2.25419282 |
| 50 | Reticulocytopenia (HP:0001896) | 2.24806965 |
| 51 | Supernumerary spleens (HP:0009799) | 2.23065699 |
| 52 | Abnormality of the renal collecting system (HP:0004742) | 2.22750753 |
| 53 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.19973320 |
| 54 | Congenital, generalized hypertrichosis (HP:0004540) | 2.17533479 |
| 55 | Progressive macrocephaly (HP:0004481) | 2.13445625 |
| 56 | Muscle fiber atrophy (HP:0100295) | 2.07026120 |
| 57 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.05109003 |
| 58 | Methylmalonic acidemia (HP:0002912) | 2.03900918 |
| 59 | Cerebral edema (HP:0002181) | 2.03298921 |
| 60 | Palmoplantar hyperkeratosis (HP:0000972) | 2.02377235 |
| 61 | Increased hepatocellular lipid droplets (HP:0006565) | 2.01872195 |
| 62 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.94976375 |
| 63 | Abnormality of T cell number (HP:0011839) | 1.92206937 |
| 64 | Renal cortical cysts (HP:0000803) | 1.92027652 |
| 65 | Paralysis (HP:0003470) | 1.89199580 |
| 66 | T lymphocytopenia (HP:0005403) | 1.89159205 |
| 67 | Abnormality of the lower motor neuron (HP:0002366) | 1.86390957 |
| 68 | Microvesicular hepatic steatosis (HP:0001414) | 1.86130581 |
| 69 | Optic disc pallor (HP:0000543) | 1.85879373 |
| 70 | Palmar hyperkeratosis (HP:0010765) | 1.84343932 |
| 71 | Amaurosis fugax (HP:0100576) | 1.83295802 |
| 72 | Abnormality of the incisor (HP:0000676) | 1.83105882 |
| 73 | Combined immunodeficiency (HP:0005387) | 1.82821575 |
| 74 | Thyroiditis (HP:0100646) | 1.81392583 |
| 75 | Type I transferrin isoform profile (HP:0003642) | 1.80802801 |
| 76 | Pustule (HP:0200039) | 1.80562908 |
| 77 | Myositis (HP:0100614) | 1.80055463 |
| 78 | Methylmalonic aciduria (HP:0012120) | 1.78611882 |
| 79 | Chronic diarrhea (HP:0002028) | 1.75353162 |
| 80 | Pallor (HP:0000980) | 1.72230404 |
| 81 | Gonadotropin excess (HP:0000837) | 1.71250715 |
| 82 | Increased serum lactate (HP:0002151) | 1.70174136 |
| 83 | Hepatocellular necrosis (HP:0001404) | 1.69477135 |
| 84 | Increased muscle lipid content (HP:0009058) | 1.67886294 |
| 85 | Gangrene (HP:0100758) | 1.66922976 |
| 86 | Dicarboxylic aciduria (HP:0003215) | 1.65708011 |
| 87 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.65708011 |
| 88 | Cleft eyelid (HP:0000625) | 1.65159697 |
| 89 | Constricted visual fields (HP:0001133) | 1.64983688 |
| 90 | Pendular nystagmus (HP:0012043) | 1.63517856 |
| 91 | Exertional dyspnea (HP:0002875) | 1.62949659 |
| 92 | Abnormality of male internal genitalia (HP:0000022) | 1.62513879 |
| 93 | Absent septum pellucidum (HP:0001331) | 1.62433643 |
| 94 | Keratoconjunctivitis (HP:0001096) | 1.62017333 |
| 95 | Abnormality of glycine metabolism (HP:0010895) | 1.60804350 |
| 96 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.60804350 |
| 97 | Clubbing of toes (HP:0100760) | 1.60709095 |
| 98 | Abnormality of placental membranes (HP:0011409) | 1.60681829 |
| 99 | Amniotic constriction ring (HP:0009775) | 1.60681829 |
| 100 | Abnormality of the labia minora (HP:0012880) | 1.59485270 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EIF2AK1 | 3.94095006 |
| 2 | SCYL2 | 3.48331034 |
| 3 | EIF2AK3 | 3.00205764 |
| 4 | MKNK2 | 2.93383020 |
| 5 | ZAK | 2.89332944 |
| 6 | NUAK1 | 2.81580915 |
| 7 | STK39 | 2.79733099 |
| 8 | TXK | 2.61690471 |
| 9 | BUB1 | 2.47355519 |
| 10 | OXSR1 | 2.39771615 |
| 11 | ADRBK2 | 2.39635775 |
| 12 | NME1 | 2.37245114 |
| 13 | VRK2 | 2.35677216 |
| 14 | TEC | 2.23652101 |
| 15 | WNK4 | 2.16356084 |
| 16 | MKNK1 | 2.13403708 |
| 17 | PRPF4B | 2.06886956 |
| 18 | NEK1 | 2.00873642 |
| 19 | TLK1 | 1.90267603 |
| 20 | TESK2 | 1.89469256 |
| 21 | GRK1 | 1.88085649 |
| 22 | TAOK2 | 1.87463873 |
| 23 | PASK | 1.87379841 |
| 24 | TAF1 | 1.76794053 |
| 25 | FES | 1.71668520 |
| 26 | CSK | 1.64994672 |
| 27 | PAK4 | 1.64445271 |
| 28 | VRK1 | 1.60835497 |
| 29 | ITK | 1.50952203 |
| 30 | WNK3 | 1.34206225 |
| 31 | ACVR1B | 1.33334924 |
| 32 | TESK1 | 1.29541710 |
| 33 | EIF2AK2 | 1.29116542 |
| 34 | MST4 | 1.28709997 |
| 35 | DYRK2 | 1.25364536 |
| 36 | LIMK1 | 1.25265022 |
| 37 | PLK3 | 1.24419630 |
| 38 | MAP3K4 | 1.24235151 |
| 39 | FRK | 1.20773031 |
| 40 | NME2 | 1.04419205 |
| 41 | STK16 | 1.03790452 |
| 42 | RPS6KA5 | 1.02725071 |
| 43 | KDR | 1.01185026 |
| 44 | MAPKAPK5 | 0.97205571 |
| 45 | CLK1 | 0.93304628 |
| 46 | IKBKB | 0.91062472 |
| 47 | BTK | 0.89146653 |
| 48 | PLK4 | 0.84448423 |
| 49 | FLT3 | 0.81548410 |
| 50 | MAP2K2 | 0.76505734 |
| 51 | SRPK1 | 0.75088678 |
| 52 | ERBB3 | 0.74925397 |
| 53 | CDC7 | 0.72720761 |
| 54 | TTK | 0.72385035 |
| 55 | IKBKE | 0.71268785 |
| 56 | GRK5 | 0.70967255 |
| 57 | TSSK6 | 0.70960824 |
| 58 | INSRR | 0.69260283 |
| 59 | IRAK4 | 0.65856450 |
| 60 | PLK1 | 0.64886053 |
| 61 | PRKCQ | 0.64174249 |
| 62 | BCKDK | 0.62358937 |
| 63 | LCK | 0.61199886 |
| 64 | WNK1 | 0.58224228 |
| 65 | PAK2 | 0.53575487 |
| 66 | ATR | 0.52956088 |
| 67 | PBK | 0.52878573 |
| 68 | FGFR1 | 0.50958921 |
| 69 | ADRBK1 | 0.50236136 |
| 70 | LYN | 0.48324598 |
| 71 | HCK | 0.42960685 |
| 72 | PLK2 | 0.41615077 |
| 73 | CSNK1A1L | 0.40912846 |
| 74 | WEE1 | 0.40260928 |
| 75 | DAPK2 | 0.39950992 |
| 76 | MATK | 0.39654310 |
| 77 | BCR | 0.39433616 |
| 78 | SYK | 0.36284734 |
| 79 | CSNK2A2 | 0.35878392 |
| 80 | PRKCG | 0.35720376 |
| 81 | STK4 | 0.33615887 |
| 82 | INSR | 0.33548970 |
| 83 | AURKB | 0.32221760 |
| 84 | CHEK1 | 0.30293700 |
| 85 | CSNK1G3 | 0.29482267 |
| 86 | CSNK2A1 | 0.28994989 |
| 87 | BMPR1B | 0.27999012 |
| 88 | RPS6KA6 | 0.27446462 |
| 89 | IGF1R | 0.27284728 |
| 90 | ZAP70 | 0.27005221 |
| 91 | RPS6KB2 | 0.24939126 |
| 92 | BLK | 0.23968698 |
| 93 | MELK | 0.23961091 |
| 94 | MAP4K2 | 0.23122708 |
| 95 | TYRO3 | 0.23064331 |
| 96 | CDK7 | 0.22635138 |
| 97 | ATM | 0.21896192 |
| 98 | TIE1 | 0.21775744 |
| 99 | TGFBR1 | 0.20605933 |
| 100 | BMPR2 | 0.20223865 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.58470823 |
| 2 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 4.24445866 |
| 3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.94672429 |
| 4 | Asthma_Homo sapiens_hsa05310 | 3.16835957 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.14204304 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.94534687 |
| 7 | Ribosome_Homo sapiens_hsa03010 | 2.90125912 |
| 8 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.88495343 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.79686505 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.75109782 |
| 11 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.28475740 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 2.17592225 |
| 13 | Mismatch repair_Homo sapiens_hsa03430 | 1.98426111 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 1.87356594 |
| 15 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.83651042 |
| 16 | RNA transport_Homo sapiens_hsa03013 | 1.75325659 |
| 17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.70747479 |
| 18 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.70425830 |
| 19 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.64618996 |
| 20 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.60935422 |
| 21 | DNA replication_Homo sapiens_hsa03030 | 1.59603702 |
| 22 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.59564656 |
| 23 | Homologous recombination_Homo sapiens_hsa03440 | 1.55373899 |
| 24 | Spliceosome_Homo sapiens_hsa03040 | 1.54255464 |
| 25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.53884908 |
| 26 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.42808745 |
| 27 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.33794438 |
| 28 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.29689462 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.28157517 |
| 30 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.24624223 |
| 31 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.24515250 |
| 32 | Basal transcription factors_Homo sapiens_hsa03022 | 1.23779306 |
| 33 | Alzheimers disease_Homo sapiens_hsa05010 | 1.19849309 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.19599899 |
| 35 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.19013597 |
| 36 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.18187344 |
| 37 | Huntingtons disease_Homo sapiens_hsa05016 | 1.15323098 |
| 38 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.14645244 |
| 39 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.12890489 |
| 40 | RNA degradation_Homo sapiens_hsa03018 | 1.07949015 |
| 41 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.06549885 |
| 42 | Base excision repair_Homo sapiens_hsa03410 | 1.06363676 |
| 43 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.86055521 |
| 44 | Purine metabolism_Homo sapiens_hsa00230 | 0.85355952 |
| 45 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.84409014 |
| 46 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.82377538 |
| 47 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.79425897 |
| 48 | Malaria_Homo sapiens_hsa05144 | 0.78737756 |
| 49 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.78421979 |
| 50 | Viral myocarditis_Homo sapiens_hsa05416 | 0.76198563 |
| 51 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.75376234 |
| 52 | Peroxisome_Homo sapiens_hsa04146 | 0.72688933 |
| 53 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.68848630 |
| 54 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.68721823 |
| 55 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.67981961 |
| 56 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.67721570 |
| 57 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.66322906 |
| 58 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.63370911 |
| 59 | Phototransduction_Homo sapiens_hsa04744 | 0.62885955 |
| 60 | Measles_Homo sapiens_hsa05162 | 0.62009038 |
| 61 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.59600951 |
| 62 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.58370069 |
| 63 | Apoptosis_Homo sapiens_hsa04210 | 0.58160528 |
| 64 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.56956701 |
| 65 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.52838902 |
| 66 | Retinol metabolism_Homo sapiens_hsa00830 | 0.50931802 |
| 67 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.49128177 |
| 68 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.47967434 |
| 69 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.47295807 |
| 70 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.47208565 |
| 71 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.46562107 |
| 72 | Legionellosis_Homo sapiens_hsa05134 | 0.46287249 |
| 73 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.46168971 |
| 74 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44405362 |
| 75 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.43919575 |
| 76 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.43437404 |
| 77 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.42421349 |
| 78 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.37602517 |
| 79 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.35516793 |
| 80 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.34257172 |
| 81 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.33584500 |
| 82 | Metabolic pathways_Homo sapiens_hsa01100 | 0.32780404 |
| 83 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.29475916 |
| 84 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.29418599 |
| 85 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.26457914 |
| 86 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.24407575 |
| 87 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.23418345 |
| 88 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.23188695 |
| 89 | HTLV-I infection_Homo sapiens_hsa05166 | 0.22316828 |
| 90 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.21647079 |
| 91 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.21001733 |
| 92 | Nicotine addiction_Homo sapiens_hsa05033 | 0.20866024 |
| 93 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.20621852 |
| 94 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.18275185 |
| 95 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.17311600 |
| 96 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.16436437 |
| 97 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.16410709 |
| 98 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.15985850 |
| 99 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.15366895 |
| 100 | Cell cycle_Homo sapiens_hsa04110 | 0.14854529 |

