

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of isotype switching to IgG isotypes (GO:0048302) | 6.45940964 |
| 2 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 5.56964760 |
| 3 | regulation of immunoglobulin secretion (GO:0051023) | 5.43066798 |
| 4 | proteasome assembly (GO:0043248) | 5.08370839 |
| 5 | DNA deamination (GO:0045006) | 4.85000434 |
| 6 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.82247759 |
| 7 | ribosome assembly (GO:0042255) | 4.21462817 |
| 8 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.06107652 |
| 9 | DNA double-strand break processing (GO:0000729) | 3.86463740 |
| 10 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.83381789 |
| 11 | isotype switching (GO:0045190) | 3.83381789 |
| 12 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.83381789 |
| 13 | maturation of SSU-rRNA (GO:0030490) | 3.81625447 |
| 14 | positive regulation of isotype switching (GO:0045830) | 3.81429806 |
| 15 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.75821292 |
| 16 | rRNA modification (GO:0000154) | 3.74552294 |
| 17 | positive regulation of DNA recombination (GO:0045911) | 3.65274608 |
| 18 | GTP biosynthetic process (GO:0006183) | 3.60989984 |
| 19 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.53945667 |
| 20 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.53356207 |
| 21 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.53352768 |
| 22 | termination of RNA polymerase III transcription (GO:0006386) | 3.53352768 |
| 23 | rRNA methylation (GO:0031167) | 3.48948867 |
| 24 | tRNA aminoacylation (GO:0043039) | 3.48343632 |
| 25 | amino acid activation (GO:0043038) | 3.48343632 |
| 26 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.46834289 |
| 27 | cullin deneddylation (GO:0010388) | 3.46702727 |
| 28 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.46531066 |
| 29 | ribosome biogenesis (GO:0042254) | 3.43195473 |
| 30 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.41479047 |
| 31 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.40558761 |
| 32 | pseudouridine synthesis (GO:0001522) | 3.40096509 |
| 33 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.39914812 |
| 34 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.39866498 |
| 35 | DNA damage response, detection of DNA damage (GO:0042769) | 3.37788712 |
| 36 | negative regulation of ligase activity (GO:0051352) | 3.35573015 |
| 37 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.35573015 |
| 38 | positive regulation of interleukin-17 production (GO:0032740) | 3.33791101 |
| 39 | tRNA aminoacylation for protein translation (GO:0006418) | 3.33444003 |
| 40 | chaperone-mediated protein transport (GO:0072321) | 3.29877138 |
| 41 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.28065453 |
| 42 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.28065453 |
| 43 | rRNA processing (GO:0006364) | 3.26805208 |
| 44 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.26314113 |
| 45 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.22280307 |
| 46 | rRNA metabolic process (GO:0016072) | 3.21809830 |
| 47 | somatic diversification of immunoglobulins (GO:0016445) | 3.20866306 |
| 48 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.20338887 |
| 49 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.20338887 |
| 50 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.20338887 |
| 51 | UTP biosynthetic process (GO:0006228) | 3.20058620 |
| 52 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.18356767 |
| 53 | negative regulation of DNA recombination (GO:0045910) | 3.15739164 |
| 54 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.14490672 |
| 55 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.14490672 |
| 56 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.11972329 |
| 57 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.11972329 |
| 58 | respiratory chain complex IV assembly (GO:0008535) | 3.11946217 |
| 59 | protein deneddylation (GO:0000338) | 3.10516505 |
| 60 | spliceosomal snRNP assembly (GO:0000387) | 3.09480183 |
| 61 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 3.08494323 |
| 62 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.07225221 |
| 63 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.06456406 |
| 64 | tRNA metabolic process (GO:0006399) | 3.05778169 |
| 65 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.99537951 |
| 66 | IMP biosynthetic process (GO:0006188) | 2.97337312 |
| 67 | ncRNA metabolic process (GO:0034660) | 2.96970789 |
| 68 | synapsis (GO:0007129) | 2.96476198 |
| 69 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.93317612 |
| 70 | ATP synthesis coupled proton transport (GO:0015986) | 2.93317612 |
| 71 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.92366222 |
| 72 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.92366222 |
| 73 | termination of RNA polymerase I transcription (GO:0006363) | 2.92199776 |
| 74 | protein refolding (GO:0042026) | 2.91998012 |
| 75 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.91650450 |
| 76 | cytidine catabolic process (GO:0006216) | 2.91169042 |
| 77 | cytidine deamination (GO:0009972) | 2.91169042 |
| 78 | cytidine metabolic process (GO:0046087) | 2.91169042 |
| 79 | regulation of podosome assembly (GO:0071801) | 2.90463053 |
| 80 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.86529115 |
| 81 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.86529115 |
| 82 | NADH dehydrogenase complex assembly (GO:0010257) | 2.86529115 |
| 83 | tRNA processing (GO:0008033) | 2.82068485 |
| 84 | positive regulation of ligase activity (GO:0051351) | 2.79991329 |
| 85 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.79288202 |
| 86 | maturation of 5.8S rRNA (GO:0000460) | 2.79235638 |
| 87 | signal peptide processing (GO:0006465) | 2.79233791 |
| 88 | ribosomal large subunit biogenesis (GO:0042273) | 2.78950965 |
| 89 | UTP metabolic process (GO:0046051) | 2.78355807 |
| 90 | protein targeting to mitochondrion (GO:0006626) | 2.77743969 |
| 91 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.75997974 |
| 92 | CTP metabolic process (GO:0046036) | 2.75374204 |
| 93 | CTP biosynthetic process (GO:0006241) | 2.75374204 |
| 94 | ncRNA processing (GO:0034470) | 2.75226013 |
| 95 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.74593264 |
| 96 | regulation of immunoglobulin production (GO:0002637) | 2.73405123 |
| 97 | mitochondrial RNA metabolic process (GO:0000959) | 2.72907110 |
| 98 | positive regulation of immunoglobulin production (GO:0002639) | 2.72370461 |
| 99 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.72294065 |
| 100 | behavioral response to nicotine (GO:0035095) | 2.71032891 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.23113445 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.35499800 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.15709835 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.87596881 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.97000911 |
| 6 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.93242853 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.92697772 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.92025074 |
| 9 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.90602339 |
| 10 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.85021719 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.83883578 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.81495486 |
| 13 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.77386817 |
| 14 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.66467754 |
| 15 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.60757072 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.56798735 |
| 17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.47722933 |
| 18 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.44265219 |
| 19 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.41257591 |
| 20 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.40148710 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.35528560 |
| 22 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.27229680 |
| 23 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.21250148 |
| 24 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.09567835 |
| 25 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.03105528 |
| 26 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.02427174 |
| 27 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.86908686 |
| 28 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.85115338 |
| 29 | VDR_22108803_ChIP-Seq_LS180_Human | 1.82680876 |
| 30 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.81576846 |
| 31 | EWS_26573619_Chip-Seq_HEK293_Human | 1.80761468 |
| 32 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.80454533 |
| 33 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.78367481 |
| 34 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.75574868 |
| 35 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.75471375 |
| 36 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.72151368 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.69995395 |
| 38 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.68610579 |
| 39 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.64757930 |
| 40 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.63393650 |
| 41 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.55928357 |
| 42 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.55790435 |
| 43 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.53911701 |
| 44 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.42833345 |
| 45 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.41642978 |
| 46 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.38458133 |
| 47 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.36308419 |
| 48 | FUS_26573619_Chip-Seq_HEK293_Human | 1.35924780 |
| 49 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.35256714 |
| 50 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.34089918 |
| 51 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.34001203 |
| 52 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.33447162 |
| 53 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.32955896 |
| 54 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.32844670 |
| 55 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.30841010 |
| 56 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.29432237 |
| 57 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.29224084 |
| 58 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.28583646 |
| 59 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.27457535 |
| 60 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.26508913 |
| 61 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.26396992 |
| 62 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.23987182 |
| 63 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.23793025 |
| 64 | P300_19829295_ChIP-Seq_ESCs_Human | 1.22192303 |
| 65 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.21224954 |
| 66 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.20192524 |
| 67 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.19946506 |
| 68 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.19253269 |
| 69 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.16743535 |
| 70 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.11827933 |
| 71 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.08554229 |
| 72 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.08317524 |
| 73 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.03252053 |
| 74 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.03069377 |
| 75 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02108488 |
| 76 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.00198654 |
| 77 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.99601433 |
| 78 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.98516558 |
| 79 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.97657998 |
| 80 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.97496986 |
| 81 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.97189109 |
| 82 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.96019216 |
| 83 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.96019216 |
| 84 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.95468060 |
| 85 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.94770473 |
| 86 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.94152132 |
| 87 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.93401563 |
| 88 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.93157835 |
| 89 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.92216161 |
| 90 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.91757347 |
| 91 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.91240346 |
| 92 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.91240346 |
| 93 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.90625778 |
| 94 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.89375338 |
| 95 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87160358 |
| 96 | GATA3_26560356_Chip-Seq_TH2_Human | 0.83109745 |
| 97 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.81731070 |
| 98 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.80909261 |
| 99 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.80399811 |
| 100 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.79850011 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 3.50631065 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 3.49540811 |
| 3 | MP0008877_abnormal_DNA_methylation | 3.46560995 |
| 4 | MP0001873_stomach_inflammation | 3.38437042 |
| 5 | MP0001348_abnormal_lacrimal_gland | 3.03837335 |
| 6 | MP0005671_abnormal_response_to | 2.94034378 |
| 7 | MP0003693_abnormal_embryo_hatching | 2.75752883 |
| 8 | MP0003786_premature_aging | 2.71891961 |
| 9 | MP0008875_abnormal_xenobiotic_pharmacok | 2.51604271 |
| 10 | MP0005084_abnormal_gallbladder_morpholo | 2.45167133 |
| 11 | MP0010094_abnormal_chromosome_stability | 2.39118139 |
| 12 | MP0006072_abnormal_retinal_apoptosis | 2.36373439 |
| 13 | MP0008872_abnormal_physiological_respon | 2.29546353 |
| 14 | MP0008058_abnormal_DNA_repair | 2.29268409 |
| 15 | MP0004147_increased_porphyrin_level | 2.27231151 |
| 16 | MP0004957_abnormal_blastocyst_morpholog | 2.08398890 |
| 17 | MP0005387_immune_system_phenotype | 2.04833626 |
| 18 | MP0001790_abnormal_immune_system | 2.04833626 |
| 19 | MP0005645_abnormal_hypothalamus_physiol | 2.02614213 |
| 20 | MP0003718_maternal_effect | 1.96154753 |
| 21 | MP0000569_abnormal_digit_pigmentation | 1.73878215 |
| 22 | MP0006292_abnormal_olfactory_placode | 1.72077930 |
| 23 | MP0001853_heart_inflammation | 1.71933865 |
| 24 | MP0008007_abnormal_cellular_replicative | 1.71922335 |
| 25 | MP0002736_abnormal_nociception_after | 1.68374991 |
| 26 | MP0004742_abnormal_vestibular_system | 1.60354380 |
| 27 | MP0002102_abnormal_ear_morphology | 1.58036296 |
| 28 | MP0003806_abnormal_nucleotide_metabolis | 1.53587170 |
| 29 | MP0004782_abnormal_surfactant_physiolog | 1.47037737 |
| 30 | MP0001800_abnormal_humoral_immune | 1.45870300 |
| 31 | MP0003111_abnormal_nucleus_morphology | 1.40703208 |
| 32 | MP0008789_abnormal_olfactory_epithelium | 1.39975644 |
| 33 | MP0009333_abnormal_splenocyte_physiolog | 1.30819702 |
| 34 | MP0008995_early_reproductive_senescence | 1.30518649 |
| 35 | MP0002277_abnormal_respiratory_mucosa | 1.29710454 |
| 36 | MP0003195_calcinosis | 1.28800750 |
| 37 | MP0001968_abnormal_touch/_nociception | 1.27439830 |
| 38 | MP0002148_abnormal_hypersensitivity_rea | 1.25877309 |
| 39 | MP0002405_respiratory_system_inflammati | 1.22736755 |
| 40 | MP0006036_abnormal_mitochondrial_physio | 1.22452374 |
| 41 | MP0001984_abnormal_olfaction | 1.22201612 |
| 42 | MP0005253_abnormal_eye_physiology | 1.20645888 |
| 43 | MP0000465_gastrointestinal_hemorrhage | 1.19549926 |
| 44 | MP0002160_abnormal_reproductive_system | 1.18971341 |
| 45 | MP0005551_abnormal_eye_electrophysiolog | 1.17943073 |
| 46 | MP0000685_abnormal_immune_system | 1.17273240 |
| 47 | MP0003878_abnormal_ear_physiology | 1.16933165 |
| 48 | MP0005377_hearing/vestibular/ear_phenot | 1.16933165 |
| 49 | MP0009785_altered_susceptibility_to | 1.15692237 |
| 50 | MP0002254_reproductive_system_inflammat | 1.12649555 |
| 51 | MP0003646_muscle_fatigue | 1.12476573 |
| 52 | MP0003077_abnormal_cell_cycle | 1.09411968 |
| 53 | MP0003186_abnormal_redox_activity | 1.09089268 |
| 54 | MP0003567_abnormal_fetal_cardiomyocyte | 1.07302338 |
| 55 | MP0002210_abnormal_sex_determination | 1.07124236 |
| 56 | MP0006035_abnormal_mitochondrial_morpho | 1.06994260 |
| 57 | MP0005389_reproductive_system_phenotype | 1.06047403 |
| 58 | MP0002938_white_spotting | 1.02626007 |
| 59 | MP0001293_anophthalmia | 1.02581507 |
| 60 | MP0005000_abnormal_immune_tolerance | 1.01594293 |
| 61 | MP0000372_irregular_coat_pigmentation | 1.01295077 |
| 62 | MP0002163_abnormal_gland_morphology | 1.01042028 |
| 63 | MP0001485_abnormal_pinna_reflex | 0.99390803 |
| 64 | MP0003011_delayed_dark_adaptation | 0.98045276 |
| 65 | MP0005187_abnormal_penis_morphology | 0.95579833 |
| 66 | MP0000653_abnormal_sex_gland | 0.91237446 |
| 67 | MP0005310_abnormal_salivary_gland | 0.90601685 |
| 68 | MP0003763_abnormal_thymus_physiology | 0.88955793 |
| 69 | MP0001502_abnormal_circadian_rhythm | 0.88682500 |
| 70 | MP0002723_abnormal_immune_serum | 0.88184093 |
| 71 | MP0005499_abnormal_olfactory_system | 0.87930327 |
| 72 | MP0005394_taste/olfaction_phenotype | 0.87930327 |
| 73 | MP0001119_abnormal_female_reproductive | 0.87906594 |
| 74 | MP0003936_abnormal_reproductive_system | 0.87137282 |
| 75 | MP0002693_abnormal_pancreas_physiology | 0.86623183 |
| 76 | MP0001929_abnormal_gametogenesis | 0.86226259 |
| 77 | MP0004215_abnormal_myocardial_fiber | 0.84591476 |
| 78 | MP0005379_endocrine/exocrine_gland_phen | 0.82330119 |
| 79 | MP0001529_abnormal_vocalization | 0.81040472 |
| 80 | MP0001663_abnormal_digestive_system | 0.77698187 |
| 81 | MP0005636_abnormal_mineral_homeostasis | 0.77458959 |
| 82 | MP0005408_hypopigmentation | 0.77286151 |
| 83 | MP0002751_abnormal_autonomic_nervous | 0.76795839 |
| 84 | MP0002272_abnormal_nervous_system | 0.76768736 |
| 85 | MP0002638_abnormal_pupillary_reflex | 0.76446805 |
| 86 | MP0005646_abnormal_pituitary_gland | 0.76008732 |
| 87 | MP0005075_abnormal_melanosome_morpholog | 0.75981871 |
| 88 | MP0002095_abnormal_skin_pigmentation | 0.75837963 |
| 89 | MP0001145_abnormal_male_reproductive | 0.75676118 |
| 90 | MP0000631_abnormal_neuroendocrine_gland | 0.74046901 |
| 91 | MP0000647_abnormal_sebaceous_gland | 0.74023448 |
| 92 | MP0000689_abnormal_spleen_morphology | 0.72663275 |
| 93 | MP0001986_abnormal_taste_sensitivity | 0.72591581 |
| 94 | MP0001764_abnormal_homeostasis | 0.71833705 |
| 95 | MP0004142_abnormal_muscle_tone | 0.71474669 |
| 96 | MP0010155_abnormal_intestine_physiology | 0.70506733 |
| 97 | MP0009745_abnormal_behavioral_response | 0.68926005 |
| 98 | MP0004145_abnormal_muscle_electrophysio | 0.68439089 |
| 99 | MP0003866_abnormal_defecation | 0.67913056 |
| 100 | MP0005395_other_phenotype | 0.67669619 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased hepatocellular lipid droplets (HP:0006565) | 4.78662706 |
| 2 | Lipid accumulation in hepatocytes (HP:0006561) | 4.35394043 |
| 3 | Stomatitis (HP:0010280) | 4.04786791 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 3.69909316 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.57931460 |
| 6 | Increased CSF lactate (HP:0002490) | 3.55252477 |
| 7 | Exertional dyspnea (HP:0002875) | 3.46883523 |
| 8 | Acute encephalopathy (HP:0006846) | 3.43616276 |
| 9 | Aplastic anemia (HP:0001915) | 3.39855053 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.39548654 |
| 11 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.34649323 |
| 12 | Renal Fanconi syndrome (HP:0001994) | 3.33258011 |
| 13 | Methylmalonic acidemia (HP:0002912) | 3.25573303 |
| 14 | Abnormality of the labia minora (HP:0012880) | 3.18896739 |
| 15 | IgG deficiency (HP:0004315) | 3.17953532 |
| 16 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.11944042 |
| 17 | Progressive macrocephaly (HP:0004481) | 3.08471448 |
| 18 | Colon cancer (HP:0003003) | 3.03191423 |
| 19 | Increased intramyocellular lipid droplets (HP:0012240) | 2.99331460 |
| 20 | Hepatocellular necrosis (HP:0001404) | 2.97998479 |
| 21 | Methylmalonic aciduria (HP:0012120) | 2.94363449 |
| 22 | Increased serum lactate (HP:0002151) | 2.83451269 |
| 23 | Abolished electroretinogram (ERG) (HP:0000550) | 2.79650429 |
| 24 | Hepatic necrosis (HP:0002605) | 2.78777240 |
| 25 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.75813573 |
| 26 | Abnormality of alanine metabolism (HP:0010916) | 2.75813573 |
| 27 | Hyperalaninemia (HP:0003348) | 2.75813573 |
| 28 | Pancreatic cysts (HP:0001737) | 2.57178197 |
| 29 | Respiratory difficulties (HP:0002880) | 2.56093545 |
| 30 | Molar tooth sign on MRI (HP:0002419) | 2.48641302 |
| 31 | Abnormality of midbrain morphology (HP:0002418) | 2.48641302 |
| 32 | Hyperglycinemia (HP:0002154) | 2.46522486 |
| 33 | Increased muscle lipid content (HP:0009058) | 2.45043798 |
| 34 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.44838692 |
| 35 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.43495402 |
| 36 | Cerebral edema (HP:0002181) | 2.43109964 |
| 37 | Optic disc pallor (HP:0000543) | 2.39235697 |
| 38 | Chorioretinal atrophy (HP:0000533) | 2.35047532 |
| 39 | Pancytopenia (HP:0001876) | 2.29342522 |
| 40 | Nephronophthisis (HP:0000090) | 2.29067466 |
| 41 | Lactic acidosis (HP:0003128) | 2.27053988 |
| 42 | Oral leukoplakia (HP:0002745) | 2.21048125 |
| 43 | Leukodystrophy (HP:0002415) | 2.20764466 |
| 44 | Hypoproteinemia (HP:0003075) | 2.19232972 |
| 45 | IgA deficiency (HP:0002720) | 2.14792191 |
| 46 | Abnormality of serum amino acid levels (HP:0003112) | 2.13587056 |
| 47 | Renal cortical cysts (HP:0000803) | 2.12941338 |
| 48 | Congenital stationary night blindness (HP:0007642) | 2.11914466 |
| 49 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.08359936 |
| 50 | Abnormality of glycine metabolism (HP:0010895) | 2.08359936 |
| 51 | Hyperglycinuria (HP:0003108) | 2.07615329 |
| 52 | Abnormality of the ileum (HP:0001549) | 2.05755618 |
| 53 | Exercise intolerance (HP:0003546) | 2.04000262 |
| 54 | Meckel diverticulum (HP:0002245) | 2.03843132 |
| 55 | Increased IgM level (HP:0003496) | 2.03420353 |
| 56 | Increased serum pyruvate (HP:0003542) | 2.02392501 |
| 57 | Lethargy (HP:0001254) | 2.02197241 |
| 58 | Abnormality of methionine metabolism (HP:0010901) | 2.01905501 |
| 59 | Carpal bone hypoplasia (HP:0001498) | 2.00126067 |
| 60 | Abnormal biliary tract physiology (HP:0012439) | 1.99583610 |
| 61 | Bile duct proliferation (HP:0001408) | 1.99583610 |
| 62 | True hermaphroditism (HP:0010459) | 1.99574488 |
| 63 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.98325028 |
| 64 | Abnormality of urine glucose concentration (HP:0011016) | 1.98086038 |
| 65 | Glycosuria (HP:0003076) | 1.98086038 |
| 66 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.96828311 |
| 67 | Abnormality of renal resorption (HP:0011038) | 1.96084974 |
| 68 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.94342233 |
| 69 | Abnormality of the pons (HP:0007361) | 1.93289509 |
| 70 | Progressive inability to walk (HP:0002505) | 1.92981285 |
| 71 | Cleft eyelid (HP:0000625) | 1.91249118 |
| 72 | Respiratory failure (HP:0002878) | 1.91111584 |
| 73 | Abnormality of homocysteine metabolism (HP:0010919) | 1.89660539 |
| 74 | Homocystinuria (HP:0002156) | 1.89660539 |
| 75 | Abnormal lung lobation (HP:0002101) | 1.88598663 |
| 76 | Microvesicular hepatic steatosis (HP:0001414) | 1.87568664 |
| 77 | Abnormality of the renal cortex (HP:0011035) | 1.86725360 |
| 78 | Hypoplasia of the pons (HP:0012110) | 1.85874050 |
| 79 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.85593010 |
| 80 | Congenital, generalized hypertrichosis (HP:0004540) | 1.82944320 |
| 81 | Pancreatic fibrosis (HP:0100732) | 1.82716123 |
| 82 | Neutropenia (HP:0001875) | 1.82594486 |
| 83 | Prominent metopic ridge (HP:0005487) | 1.81402810 |
| 84 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.79030653 |
| 85 | Degeneration of anterior horn cells (HP:0002398) | 1.77447547 |
| 86 | Abnormality of the anterior horn cell (HP:0006802) | 1.77447547 |
| 87 | Abnormality of the renal medulla (HP:0100957) | 1.75010734 |
| 88 | Rhabdomyosarcoma (HP:0002859) | 1.73009882 |
| 89 | Hyperphosphaturia (HP:0003109) | 1.72604125 |
| 90 | Abnormality of vitamin B metabolism (HP:0004340) | 1.71338948 |
| 91 | Large for gestational age (HP:0001520) | 1.71246127 |
| 92 | Bilateral microphthalmos (HP:0007633) | 1.69642577 |
| 93 | Pendular nystagmus (HP:0012043) | 1.69591598 |
| 94 | Inability to walk (HP:0002540) | 1.69428836 |
| 95 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.69127202 |
| 96 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.69127202 |
| 97 | Bifid tongue (HP:0010297) | 1.68718174 |
| 98 | Clitoromegaly (HP:0000057) | 1.67493417 |
| 99 | Cerebral hypomyelination (HP:0006808) | 1.66664756 |
| 100 | Abnormality of the preputium (HP:0100587) | 1.66222084 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 4.50599491 |
| 2 | BUB1 | 4.48247657 |
| 3 | ZAK | 3.20314379 |
| 4 | EIF2AK3 | 3.00301464 |
| 5 | EIF2AK1 | 2.98749834 |
| 6 | MST4 | 2.91922992 |
| 7 | PBK | 2.68613095 |
| 8 | NUAK1 | 2.48092314 |
| 9 | TXK | 2.36397384 |
| 10 | NEK1 | 2.30075820 |
| 11 | TLK1 | 2.24334821 |
| 12 | SRPK1 | 2.23723074 |
| 13 | MAP4K2 | 2.16850959 |
| 14 | VRK1 | 2.00784910 |
| 15 | BMPR1B | 1.96125184 |
| 16 | PLK3 | 1.95081810 |
| 17 | WNK3 | 1.74562381 |
| 18 | MKNK2 | 1.68903112 |
| 19 | TRIM28 | 1.67790216 |
| 20 | NME1 | 1.64605488 |
| 21 | VRK2 | 1.64331526 |
| 22 | TNIK | 1.46187134 |
| 23 | TTK | 1.44248093 |
| 24 | MKNK1 | 1.43323951 |
| 25 | ADRBK2 | 1.41625316 |
| 26 | CDC7 | 1.28778748 |
| 27 | FRK | 1.27194929 |
| 28 | OXSR1 | 1.26995613 |
| 29 | PINK1 | 1.23397007 |
| 30 | GRK1 | 1.23100633 |
| 31 | RPS6KA4 | 1.22706002 |
| 32 | MAP3K12 | 1.17340486 |
| 33 | STK16 | 1.11545232 |
| 34 | DYRK2 | 1.11405814 |
| 35 | PLK4 | 0.99209406 |
| 36 | TAF1 | 0.96995606 |
| 37 | PLK1 | 0.96429409 |
| 38 | WEE1 | 0.95117504 |
| 39 | TAOK3 | 0.94792856 |
| 40 | BCKDK | 0.93707294 |
| 41 | BCR | 0.93481177 |
| 42 | TIE1 | 0.93425533 |
| 43 | PAK4 | 0.90273898 |
| 44 | PNCK | 0.87969150 |
| 45 | EIF2AK2 | 0.87492863 |
| 46 | CDK8 | 0.85410582 |
| 47 | ALK | 0.84635424 |
| 48 | RPS6KA5 | 0.84075577 |
| 49 | CSNK1G1 | 0.83054518 |
| 50 | ATR | 0.82987233 |
| 51 | SIK3 | 0.82845076 |
| 52 | CASK | 0.79388045 |
| 53 | STK4 | 0.78473044 |
| 54 | CSNK1G3 | 0.76234367 |
| 55 | WNK4 | 0.75916942 |
| 56 | ITK | 0.73047018 |
| 57 | CSNK1A1L | 0.72322516 |
| 58 | WNK1 | 0.71461064 |
| 59 | BRSK2 | 0.68733892 |
| 60 | TEC | 0.68154613 |
| 61 | TGFBR1 | 0.67166496 |
| 62 | PASK | 0.64483923 |
| 63 | CSNK1G2 | 0.62561537 |
| 64 | IKBKB | 0.61582522 |
| 65 | DAPK1 | 0.60575578 |
| 66 | MAPKAPK5 | 0.59912255 |
| 67 | ACVR1B | 0.59272468 |
| 68 | MAPK15 | 0.59068382 |
| 69 | PLK2 | 0.55937745 |
| 70 | CLK1 | 0.54699085 |
| 71 | CDK3 | 0.52638676 |
| 72 | STK39 | 0.51744125 |
| 73 | AURKB | 0.50624197 |
| 74 | CSNK2A2 | 0.49108326 |
| 75 | CSNK2A1 | 0.46028970 |
| 76 | CDK9 | 0.44661812 |
| 77 | MYLK | 0.43426215 |
| 78 | BMPR2 | 0.42284042 |
| 79 | GRK7 | 0.41274470 |
| 80 | AKT3 | 0.41245982 |
| 81 | FGFR1 | 0.40435342 |
| 82 | DAPK3 | 0.36970569 |
| 83 | CHEK1 | 0.36932055 |
| 84 | CHEK2 | 0.36642399 |
| 85 | CDK19 | 0.36621406 |
| 86 | DYRK3 | 0.36222952 |
| 87 | ATM | 0.35682287 |
| 88 | PAK3 | 0.34833156 |
| 89 | NME2 | 0.34797705 |
| 90 | NLK | 0.34602650 |
| 91 | INSRR | 0.32812033 |
| 92 | AURKA | 0.31799606 |
| 93 | CSNK1A1 | 0.30684823 |
| 94 | MAP3K4 | 0.30434243 |
| 95 | MAP2K6 | 0.30008628 |
| 96 | BLK | 0.29007614 |
| 97 | AKT2 | 0.28953505 |
| 98 | PRKCE | 0.25019453 |
| 99 | CHUK | 0.24166024 |
| 100 | CSNK1E | 0.24044498 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.47691416 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.65750959 |
| 3 | Asthma_Homo sapiens_hsa05310 | 2.91347401 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.88760535 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.73037565 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.62643367 |
| 7 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.58603816 |
| 8 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.47811932 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.36677107 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.21216827 |
| 11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.20788575 |
| 12 | Mismatch repair_Homo sapiens_hsa03430 | 2.13424065 |
| 13 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.00929651 |
| 14 | Ribosome_Homo sapiens_hsa03010 | 1.95588944 |
| 15 | Basal transcription factors_Homo sapiens_hsa03022 | 1.86690989 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.86011036 |
| 17 | DNA replication_Homo sapiens_hsa03030 | 1.85383952 |
| 18 | RNA transport_Homo sapiens_hsa03013 | 1.84623159 |
| 19 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.81526443 |
| 20 | Homologous recombination_Homo sapiens_hsa03440 | 1.80989715 |
| 21 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.72685301 |
| 22 | Parkinsons disease_Homo sapiens_hsa05012 | 1.68781679 |
| 23 | Spliceosome_Homo sapiens_hsa03040 | 1.62777940 |
| 24 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.55258681 |
| 25 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.51673441 |
| 26 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.51034977 |
| 27 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.50359319 |
| 28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.46023316 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.43392631 |
| 30 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.36869545 |
| 31 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.35613378 |
| 32 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.29077089 |
| 33 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.27686239 |
| 34 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.27482707 |
| 35 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.22417907 |
| 36 | Base excision repair_Homo sapiens_hsa03410 | 1.17688022 |
| 37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.16980791 |
| 38 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.13567516 |
| 39 | Purine metabolism_Homo sapiens_hsa00230 | 1.10955580 |
| 40 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.10763045 |
| 41 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.07270078 |
| 42 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.07244571 |
| 43 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.06386928 |
| 44 | Huntingtons disease_Homo sapiens_hsa05016 | 1.06174551 |
| 45 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.05441306 |
| 46 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.03232589 |
| 47 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.02747933 |
| 48 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.00901647 |
| 49 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.88919654 |
| 50 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.88016853 |
| 51 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.87715655 |
| 52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.84786963 |
| 53 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.84465561 |
| 54 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.84406462 |
| 55 | Phototransduction_Homo sapiens_hsa04744 | 0.78426442 |
| 56 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.77779328 |
| 57 | Alzheimers disease_Homo sapiens_hsa05010 | 0.74166286 |
| 58 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.73281927 |
| 59 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.70636721 |
| 60 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.67067700 |
| 61 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.65821190 |
| 62 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.63994797 |
| 63 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.63519102 |
| 64 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.61385381 |
| 65 | Peroxisome_Homo sapiens_hsa04146 | 0.59843726 |
| 66 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.57692348 |
| 67 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.57649090 |
| 68 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.57201867 |
| 69 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.56035451 |
| 70 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.50716782 |
| 71 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.48474356 |
| 72 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.47365679 |
| 73 | Measles_Homo sapiens_hsa05162 | 0.46525106 |
| 74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46364534 |
| 75 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.45849848 |
| 76 | Viral myocarditis_Homo sapiens_hsa05416 | 0.45706262 |
| 77 | Carbon metabolism_Homo sapiens_hsa01200 | 0.45649788 |
| 78 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.45380408 |
| 79 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.45066813 |
| 80 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.45003592 |
| 81 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.42899149 |
| 82 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.41621309 |
| 83 | Cell cycle_Homo sapiens_hsa04110 | 0.39288876 |
| 84 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.39037228 |
| 85 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.35901977 |
| 86 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.35573042 |
| 87 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.35295818 |
| 88 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.34296278 |
| 89 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.32187135 |
| 90 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.30839413 |
| 91 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.30716630 |
| 92 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.28205031 |
| 93 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.27262321 |
| 94 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.26290622 |
| 95 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.26007776 |
| 96 | Mineral absorption_Homo sapiens_hsa04978 | 0.23834389 |
| 97 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.23427554 |
| 98 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.23393146 |
| 99 | Retinol metabolism_Homo sapiens_hsa00830 | 0.23044143 |
| 100 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.22870826 |

