HSPD1P7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of isotype switching to IgG isotypes (GO:0048302)5.39216752
2positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)5.34240454
3proteasome assembly (GO:0043248)5.31058859
4establishment of protein localization to mitochondrial membrane (GO:0090151)4.92315578
5maturation of 5.8S rRNA (GO:0000460)4.66055547
6regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)4.64526475
7chaperone-mediated protein transport (GO:0072321)4.53612152
8DNA deamination (GO:0045006)4.51898625
9positive regulation of isotype switching (GO:0045830)4.38837175
10regulation of immunoglobulin secretion (GO:0051023)4.28240076
11negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.23399279
12water-soluble vitamin biosynthetic process (GO:0042364)4.14369045
13positive regulation of DNA recombination (GO:0045911)4.10854043
14ribosome assembly (GO:0042255)3.97836188
15IMP biosynthetic process (GO:0006188)3.95343861
16positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.93506731
17regulation of chronic inflammatory response (GO:0002676)3.90112342
18exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.88526759
19NADH dehydrogenase complex assembly (GO:0010257)3.86360628
20mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.86360628
21mitochondrial respiratory chain complex I assembly (GO:0032981)3.86360628
22regulation of cellular amino acid metabolic process (GO:0006521)3.85995522
23GTP biosynthetic process (GO:0006183)3.85354984
24regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.84260857
25nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.83695454
26negative regulation of ligase activity (GO:0051352)3.83528286
27negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.83528286
28tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.73931813
29RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.73931813
30DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.67649029
31signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.65409298
32signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.65409298
33signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.65409298
34anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.60120917
35rRNA modification (GO:0000154)3.59994929
36ATP synthesis coupled proton transport (GO:0015986)3.59868571
37energy coupled proton transport, down electrochemical gradient (GO:0015985)3.59868571
38protein complex biogenesis (GO:0070271)3.59622823
39intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.59583491
40signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.59583491
41protein neddylation (GO:0045116)3.54269865
42UTP biosynthetic process (GO:0006228)3.52888793
43regulation of regulatory T cell differentiation (GO:0045589)3.52670889
44signal transduction involved in DNA damage checkpoint (GO:0072422)3.52595897
45signal transduction involved in DNA integrity checkpoint (GO:0072401)3.52595897
46maturation of SSU-rRNA (GO:0030490)3.51124617
47rRNA methylation (GO:0031167)3.49032043
48transcription elongation from RNA polymerase I promoter (GO:0006362)3.48744193
49viral mRNA export from host cell nucleus (GO:0046784)3.48431638
50signal transduction involved in cell cycle checkpoint (GO:0072395)3.45455732
51rRNA processing (GO:0006364)3.42819652
52termination of RNA polymerase I transcription (GO:0006363)3.42314520
53mitochondrial respiratory chain complex assembly (GO:0033108)3.41714260
54RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.41697776
55mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.39091888
56nucleobase biosynthetic process (GO:0046112)3.36891517
57positive regulation of immunoglobulin mediated immune response (GO:0002891)3.32870089
58positive regulation of B cell mediated immunity (GO:0002714)3.32870089
59DNA catabolic process, exonucleolytic (GO:0000738)3.32700540
60rRNA metabolic process (GO:0016072)3.30631880
61positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.26840199
62folic acid-containing compound biosynthetic process (GO:0009396)3.26656500
63ribosome biogenesis (GO:0042254)3.22758132
64respiratory chain complex IV assembly (GO:0008535)3.21612784
65spliceosomal snRNP assembly (GO:0000387)3.18725435
66pseudouridine synthesis (GO:0001522)3.15817365
67IMP metabolic process (GO:0046040)3.15668214
68antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.13372370
69positive regulation of ligase activity (GO:0051351)3.12115092
70histone mRNA metabolic process (GO:0008334)3.10675715
71regulation of podosome assembly (GO:0071801)3.10234625
72regulation of isotype switching (GO:0045191)3.09941573
73peptidyl-histidine modification (GO:0018202)3.09404241
74intracellular protein transmembrane import (GO:0044743)3.09284971
75regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033393.07593445
76UTP metabolic process (GO:0046051)3.07494141
77DNA replication checkpoint (GO:0000076)3.03472647
78protein K6-linked ubiquitination (GO:0085020)3.03061778
79ribosomal large subunit biogenesis (GO:0042273)3.01731406
80tRNA aminoacylation (GO:0043039)3.00940056
81amino acid activation (GO:0043038)3.00940056
82positive regulation of immunoglobulin production (GO:0002639)2.99178390
83tRNA aminoacylation for protein translation (GO:0006418)2.98827347
847-methylguanosine mRNA capping (GO:0006370)2.98360846
85regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.97799581
86chromatin remodeling at centromere (GO:0031055)2.96475465
87CENP-A containing nucleosome assembly (GO:0034080)2.95909434
88tRNA processing (GO:0008033)2.93792303
89tRNA metabolic process (GO:0006399)2.92932889
90purine nucleobase biosynthetic process (GO:0009113)2.92257978
91replication fork processing (GO:0031297)2.91246897
927-methylguanosine RNA capping (GO:0009452)2.91017992
93RNA capping (GO:0036260)2.91017992
94somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.88799764
95isotype switching (GO:0045190)2.88799764
96somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.88799764
97pteridine-containing compound biosynthetic process (GO:0042559)2.88069437
98ncRNA metabolic process (GO:0034660)2.87274815
99termination of RNA polymerase III transcription (GO:0006386)2.86942011
100transcription elongation from RNA polymerase III promoter (GO:0006385)2.86942011

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human5.62020373
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.74822099
3EST1_17652178_ChIP-ChIP_JURKAT_Human4.30309302
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.63151416
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.37599182
6HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.33442382
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.14243834
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.09341445
9MYC_18555785_ChIP-Seq_MESCs_Mouse3.05495441
10VDR_23849224_ChIP-Seq_CD4+_Human3.04952271
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.97853711
12ELK1_19687146_ChIP-ChIP_HELA_Human2.97654315
13CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.72828965
14FOXP3_21729870_ChIP-Seq_TREG_Human2.46160039
15NOTCH1_21737748_ChIP-Seq_TLL_Human2.45462824
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.44830011
17FLI1_27457419_Chip-Seq_LIVER_Mouse2.32411368
18MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.25754616
19VDR_22108803_ChIP-Seq_LS180_Human2.25063880
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.18923905
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.17889461
22SRF_21415370_ChIP-Seq_HL-1_Mouse2.16434413
23PADI4_21655091_ChIP-ChIP_MCF-7_Human2.14906756
24MYC_19030024_ChIP-ChIP_MESCs_Mouse2.14597132
25E2F7_22180533_ChIP-Seq_HELA_Human2.13434085
26NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.13394278
27MYC_18358816_ChIP-ChIP_MESCs_Mouse1.99605235
28PCGF2_27294783_Chip-Seq_ESCs_Mouse1.96735885
29DCP1A_22483619_ChIP-Seq_HELA_Human1.95456578
30FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.95274485
31HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.92501140
32MYC_18940864_ChIP-ChIP_HL60_Human1.86954864
33ZNF274_21170338_ChIP-Seq_K562_Hela1.85151360
34MYC_19079543_ChIP-ChIP_MESCs_Mouse1.83505365
35PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.81474554
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.79385300
37EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.79076262
38EWS_26573619_Chip-Seq_HEK293_Human1.78542965
39CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.76666286
40TTF2_22483619_ChIP-Seq_HELA_Human1.75879836
41HOXB4_20404135_ChIP-ChIP_EML_Mouse1.72036125
42FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.71281315
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.66511946
44GABP_19822575_ChIP-Seq_HepG2_Human1.64169833
45IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.59913368
46MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.58462370
47SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.58140384
48CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.56185424
49PCGF2_27294783_Chip-Seq_NPCs_Mouse1.54452717
50ELK1_22589737_ChIP-Seq_MCF10A_Human1.52959328
51XRN2_22483619_ChIP-Seq_HELA_Human1.51753836
52DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.50462161
53E2F1_18555785_ChIP-Seq_MESCs_Mouse1.50412197
54NELFA_20434984_ChIP-Seq_ESCs_Mouse1.43630463
55THAP11_20581084_ChIP-Seq_MESCs_Mouse1.38661412
56YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.35307532
57HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.34838073
58HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.22107683
59POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.17318553
60SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.17166701
61POU5F1_16153702_ChIP-ChIP_HESCs_Human1.16410275
62FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.15177256
63SUZ12_27294783_Chip-Seq_NPCs_Mouse1.14795250
64ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.13585522
65KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.12230962
66TP53_22573176_ChIP-Seq_HFKS_Human1.11888155
67MYCN_18555785_ChIP-Seq_MESCs_Mouse1.09730755
68NFE2_27457419_Chip-Seq_LIVER_Mouse1.08688733
69EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.07852210
70GATA1_22025678_ChIP-Seq_K562_Human1.03560066
71FUS_26573619_Chip-Seq_HEK293_Human0.97251327
72EZH2_27294783_Chip-Seq_NPCs_Mouse0.96984456
73MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.96851421
74FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.96064759
75NANOG_19829295_ChIP-Seq_ESCs_Human0.95960614
76SOX2_19829295_ChIP-Seq_ESCs_Human0.95960614
77E2F1_21310950_ChIP-Seq_MCF-7_Human0.95444405
78P300_19829295_ChIP-Seq_ESCs_Human0.95304690
79IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.94478713
80ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.93900624
81FOXA1_25329375_ChIP-Seq_VCAP_Human0.93274637
82FOXA1_27270436_Chip-Seq_PROSTATE_Human0.93274637
83POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.91474059
84NANOG_16153702_ChIP-ChIP_HESCs_Human0.90876081
85GATA3_26560356_Chip-Seq_TH2_Human0.90462921
86SALL4_22934838_ChIP-ChIP_CD34+_Human0.89739878
87TAF15_26573619_Chip-Seq_HEK293_Human0.86654977
88ER_23166858_ChIP-Seq_MCF-7_Human0.85092003
89GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.84836397
90CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.84445875
91EGR1_23403033_ChIP-Seq_LIVER_Mouse0.84247094
92IRF8_21731497_ChIP-ChIP_J774_Mouse0.84000298
93STAT4_19710469_ChIP-ChIP_TH1__Mouse0.83958934
94PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.81376767
95RBPJ_21746931_ChIP-Seq_IB4_Human0.80462199
96AUTS2_25519132_ChIP-Seq_293T-REX_Human0.79637053
97SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.78797908
98PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.78387640
99CTBP1_25329375_ChIP-Seq_LNCAP_Human0.77243624
100CRX_20693478_ChIP-Seq_RETINA_Mouse0.77040562

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008058_abnormal_DNA_repair4.07102722
2MP0001835_abnormal_antigen_presentation3.60670625
3MP0001873_stomach_inflammation3.55316333
4MP0003693_abnormal_embryo_hatching3.23609587
5MP0002138_abnormal_hepatobiliary_system3.05866349
6MP0005671_abnormal_response_to2.87466578
7MP0004957_abnormal_blastocyst_morpholog2.85343344
8MP0008057_abnormal_DNA_replication2.59103902
9MP0003195_calcinosis2.54772401
10MP0001853_heart_inflammation2.42788603
11MP0003806_abnormal_nucleotide_metabolis2.41140148
12MP0010094_abnormal_chromosome_stability2.30416697
13MP0008875_abnormal_xenobiotic_pharmacok2.14151557
14MP0003718_maternal_effect2.13084095
15MP0008872_abnormal_physiological_respon2.04905308
16MP0002006_tumorigenesis2.00731395
17MP0009333_abnormal_splenocyte_physiolog1.98039354
18MP0003890_abnormal_embryonic-extraembry1.96138431
19MP0005084_abnormal_gallbladder_morpholo1.93954179
20MP0002938_white_spotting1.91991461
21MP0000685_abnormal_immune_system1.89715898
22MP0005387_immune_system_phenotype1.89212914
23MP0001790_abnormal_immune_system1.89212914
24MP0003786_premature_aging1.86377163
25MP0001348_abnormal_lacrimal_gland1.79752149
26MP0006072_abnormal_retinal_apoptosis1.77099885
27MP0005408_hypopigmentation1.74007456
28MP0002102_abnormal_ear_morphology1.73606691
29MP0009785_altered_susceptibility_to1.72984113
30MP0003077_abnormal_cell_cycle1.72706066
31MP0002148_abnormal_hypersensitivity_rea1.68699632
32MP0003186_abnormal_redox_activity1.68657153
33MP0002166_altered_tumor_susceptibility1.67778576
34MP0001529_abnormal_vocalization1.61012678
35MP0002163_abnormal_gland_morphology1.57484973
36MP0003111_abnormal_nucleus_morphology1.57089700
37MP0003878_abnormal_ear_physiology1.52278322
38MP0005377_hearing/vestibular/ear_phenot1.52278322
39MP0001881_abnormal_mammary_gland1.46370096
40MP0001800_abnormal_humoral_immune1.45809013
41MP0004147_increased_porphyrin_level1.44778877
42MP0001968_abnormal_touch/_nociception1.43280591
43MP0000372_irregular_coat_pigmentation1.42902265
44MP0008007_abnormal_cellular_replicative1.37749199
45MP0009697_abnormal_copulation1.35925636
46MP0002736_abnormal_nociception_after1.33341223
47MP0002405_respiratory_system_inflammati1.32473643
48MP0001501_abnormal_sleep_pattern1.30601012
49MP0006292_abnormal_olfactory_placode1.22226277
50MP0006036_abnormal_mitochondrial_physio1.12839053
51MP0006082_CNS_inflammation1.08217256
52MP0003300_gastrointestinal_ulcer1.05992061
53MP0001984_abnormal_olfaction1.05074556
54MP0004782_abnormal_surfactant_physiolog1.04576224
55MP0004142_abnormal_muscle_tone1.02984836
56MP0005075_abnormal_melanosome_morpholog1.02720801
57MP0008877_abnormal_DNA_methylation1.02675823
58MP0003936_abnormal_reproductive_system1.01698383
59MP0002837_dystrophic_cardiac_calcinosis1.01215971
60MP0003567_abnormal_fetal_cardiomyocyte1.00843594
61MP0005000_abnormal_immune_tolerance0.99167533
62MP0004145_abnormal_muscle_electrophysio0.98729089
63MP0008932_abnormal_embryonic_tissue0.94092161
64MP0003950_abnormal_plasma_membrane0.93699718
65MP0002723_abnormal_immune_serum0.93230217
66MP0004885_abnormal_endolymph0.89081819
67MP0002822_catalepsy0.87266447
68MP0002210_abnormal_sex_determination0.85982180
69MP0005551_abnormal_eye_electrophysiolog0.85039883
70MP0001905_abnormal_dopamine_level0.83958704
71MP0003436_decreased_susceptibility_to0.79718256
72MP0005379_endocrine/exocrine_gland_phen0.77725384
73MP0000627_abnormal_mammary_gland0.76507135
74MP0002751_abnormal_autonomic_nervous0.76160335
75MP0001764_abnormal_homeostasis0.75722295
76MP0001845_abnormal_inflammatory_respons0.75481091
77MP0003763_abnormal_thymus_physiology0.74986744
78MP0005636_abnormal_mineral_homeostasis0.74978267
79MP0005253_abnormal_eye_physiology0.74680678
80MP0005645_abnormal_hypothalamus_physiol0.73799907
81MP0002693_abnormal_pancreas_physiology0.73436258
82MP0000689_abnormal_spleen_morphology0.73039872
83MP0004742_abnormal_vestibular_system0.72345895
84MP0002420_abnormal_adaptive_immunity0.72092283
85MP0001663_abnormal_digestive_system0.71500630
86MP0002019_abnormal_tumor_incidence0.71443256
87MP0003137_abnormal_impulse_conducting0.71176590
88MP0010155_abnormal_intestine_physiology0.70966666
89MP0001188_hyperpigmentation0.69804970
90MP0002452_abnormal_antigen_presenting0.68886097
91MP0002277_abnormal_respiratory_mucosa0.68259815
92MP0000631_abnormal_neuroendocrine_gland0.68207984
93MP0001819_abnormal_immune_cell0.66712135
94MP0006035_abnormal_mitochondrial_morpho0.65786835
95MP0001293_anophthalmia0.65637506
96MP0004215_abnormal_myocardial_fiber0.63879026
97MP0000703_abnormal_thymus_morphology0.63556597
98MP0001730_embryonic_growth_arrest0.62694699
99MP0010030_abnormal_orbit_morphology0.61539762
100MP0000613_abnormal_salivary_gland0.61151642

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.73112537
2Acute encephalopathy (HP:0006846)4.18668877
3Abnormal mitochondria in muscle tissue (HP:0008316)4.10832448
4Mitochondrial inheritance (HP:0001427)3.99621015
5Progressive macrocephaly (HP:0004481)3.93735528
6Increased CSF lactate (HP:0002490)3.93618657
7Abnormality of the pons (HP:0007361)3.62085471
8Stomatitis (HP:0010280)3.53147138
9Hepatocellular necrosis (HP:0001404)3.44932277
10Hypoproteinemia (HP:0003075)3.42176339
11Hepatic necrosis (HP:0002605)3.33892914
12Increased hepatocellular lipid droplets (HP:0006565)3.32947100
13Pancreatic cysts (HP:0001737)3.24644533
143-Methylglutaconic aciduria (HP:0003535)3.24347648
15Methylmalonic acidemia (HP:0002912)3.23474372
16IgG deficiency (HP:0004315)3.04777299
17Cerebral edema (HP:0002181)3.04537378
18Reduced antithrombin III activity (HP:0001976)3.03286305
19Molar tooth sign on MRI (HP:0002419)3.02274307
20Abnormality of midbrain morphology (HP:0002418)3.02274307
21Hypoplasia of the pons (HP:0012110)3.01101110
22Lipid accumulation in hepatocytes (HP:0006561)2.97023461
23Increased serum pyruvate (HP:0003542)2.90604391
24Increased serum lactate (HP:0002151)2.86873273
25Optic disc pallor (HP:0000543)2.85149503
26Type I transferrin isoform profile (HP:0003642)2.84035564
27Congenital, generalized hypertrichosis (HP:0004540)2.70315720
28Oral leukoplakia (HP:0002745)2.68737806
29Leukodystrophy (HP:0002415)2.66398200
30Exercise intolerance (HP:0003546)2.66048437
31Methylmalonic aciduria (HP:0012120)2.66032963
32Abnormality of glycolysis (HP:0004366)2.65529642
33Abnormality of the renal cortex (HP:0011035)2.65229402
34Meckel diverticulum (HP:0002245)2.64246767
35Abnormality of the ileum (HP:0001549)2.60000383
36Abnormality of the labia minora (HP:0012880)2.55767471
37Aplasia/Hypoplasia involving the musculature (HP:0001460)2.52799093
38Aplasia/Hypoplasia of the uvula (HP:0010293)2.46940171
39Renal cortical cysts (HP:0000803)2.46764527
40Respiratory failure (HP:0002878)2.40502939
41Duplicated collecting system (HP:0000081)2.38876989
42Abnormality of alanine metabolism (HP:0010916)2.36391696
43Hyperalaninemia (HP:0003348)2.36391696
44Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.36391696
45Pancreatic fibrosis (HP:0100732)2.35257556
46Progressive inability to walk (HP:0002505)2.34514086
47Abnormality of the preputium (HP:0100587)2.33495463
48Nephronophthisis (HP:0000090)2.31417590
49Lactic acidosis (HP:0003128)2.29726949
50Testicular atrophy (HP:0000029)2.25965062
51Increased IgM level (HP:0003496)2.24940684
52Abnormality of the anterior horn cell (HP:0006802)2.24421188
53Degeneration of anterior horn cells (HP:0002398)2.24421188
54Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.22628474
55Decreased activity of mitochondrial respiratory chain (HP:0008972)2.22506286
56Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.22506286
57Colon cancer (HP:0003003)2.21214372
58Tubular atrophy (HP:0000092)2.20734405
59Microvesicular hepatic steatosis (HP:0001414)2.19045453
60Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.17650284
61Renal Fanconi syndrome (HP:0001994)2.15354023
62Abnormality of the renal collecting system (HP:0004742)2.13951531
63Lethargy (HP:0001254)2.11294353
64Constricted visual fields (HP:0001133)2.09784043
65Abolished electroretinogram (ERG) (HP:0000550)2.08933023
66Inability to walk (HP:0002540)2.08228910
67Pancytopenia (HP:0001876)2.07780037
68Chromsome breakage (HP:0040012)2.04590925
69Bile duct proliferation (HP:0001408)2.03372185
70Abnormal biliary tract physiology (HP:0012439)2.03372185
71Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.00726118
72Abnormal protein N-linked glycosylation (HP:0012347)2.00726118
73Abnormal protein glycosylation (HP:0012346)2.00726118
74Abnormal glycosylation (HP:0012345)2.00726118
75Aplasia/hypoplasia of the uterus (HP:0008684)2.00617201
76Exertional dyspnea (HP:0002875)2.00313895
77Chromosomal breakage induced by crosslinking agents (HP:0003221)1.98532581
78CNS demyelination (HP:0007305)1.92820173
79Abnormality of the renal medulla (HP:0100957)1.91716314
80Pendular nystagmus (HP:0012043)1.91707235
81Abnormality of chromosome stability (HP:0003220)1.91214140
82Abnormality of DNA repair (HP:0003254)1.88256134
83Increased intramyocellular lipid droplets (HP:0012240)1.87877428
84Amniotic constriction ring (HP:0009775)1.86565087
85Abnormality of placental membranes (HP:0011409)1.86565087
86Nausea (HP:0002018)1.86460817
87Carpal bone hypoplasia (HP:0001498)1.85923362
88Delayed CNS myelination (HP:0002188)1.84459282
89Horseshoe kidney (HP:0000085)1.83634801
90Generalized aminoaciduria (HP:0002909)1.83429860
91True hermaphroditism (HP:0010459)1.81911796
92Absent thumb (HP:0009777)1.81841939
93Aplastic anemia (HP:0001915)1.81481124
94Megaloblastic anemia (HP:0001889)1.80869507
95Large for gestational age (HP:0001520)1.79371945
96Abnormality of methionine metabolism (HP:0010901)1.79192661
97Cellular immunodeficiency (HP:0005374)1.78251066
98Abnormality of aspartate family amino acid metabolism (HP:0010899)1.77059586
99Clubbing of toes (HP:0100760)1.76757717
100Opisthotonus (HP:0002179)1.73907505

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TSSK64.53059847
2BMPR1B4.40921374
3MST43.92311649
4ZAK3.68691132
5EIF2AK33.25209258
6EIF2AK13.22165330
7TXK3.13968573
8VRK23.12545556
9BUB13.00161889
10VRK12.58118452
11TLK12.53097927
12NME12.42489646
13PBK2.34405692
14NUAK12.34372883
15NEK12.19032518
16PLK32.16679773
17SRPK12.14023392
18TRIM281.99802262
19TAF11.94892170
20PASK1.68898081
21ADRBK21.53043576
22MKNK21.35884912
23TTK1.31157895
24TGFBR11.30655414
25EIF2AK21.22730758
26ALK1.21312614
27CDC71.19286136
28GRK11.15720252
29WNK41.13022335
30TAOK31.11799861
31TNIK1.11607980
32DYRK21.10899476
33STK391.03047528
34PLK41.01617748
35STK160.97579719
36MKNK10.95378048
37WNK30.89987243
38MAP4K20.88391017
39TEC0.85790480
40MAP4K10.83392656
41WEE10.81918507
42FRK0.80231335
43ATR0.79763760
44CDK80.79009776
45PLK10.77560453
46DAPK10.72928181
47BCKDK0.70780655
48STK40.69184430
49TIE10.64692865
50RPS6KA50.63696231
51PDK20.62672343
52AKT30.62103380
53RPS6KA40.60852098
54PLK20.57738466
55SIK30.57657418
56DYRK30.53475851
57AURKB0.52521692
58MAPKAPK30.50428292
59OXSR10.49764981
60FGFR10.48893642
61IKBKB0.48396726
62ITK0.48307310
63STK38L0.43897782
64ATM0.42980821
65CHEK20.42731088
66IKBKE0.41756301
67CDK90.40009619
68CSNK2A20.39808340
69CSNK2A10.39010152
70CCNB10.38336317
71PHKG10.36244243
72PHKG20.36244243
73PAK40.35415039
74CSNK1A1L0.34084904
75BRSK20.34010882
76NME20.32289844
77FLT30.30919899
78NEK90.30545522
79PNCK0.30210828
80CHEK10.30140502
81LATS10.29610141
82CSNK1G10.29398360
83INSRR0.29310521
84DAPK30.28535222
85NLK0.28502962
86CSNK1G30.28404064
87CAMK2D0.27727561
88AURKA0.27631605
89ERBB40.27258273
90PRKCE0.26520125
91IRAK10.25459842
92CSNK1A10.24915031
93PRKCG0.24897080
94CSNK1E0.24515991
95BCR0.24484066
96PRKCQ0.24281337
97HIPK20.24206136
98MAP3K120.22763456
99STK30.21553679
100ACVR1B0.21547248

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030505.34783210
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.71506516
3Protein export_Homo sapiens_hsa030602.99901640
4Oxidative phosphorylation_Homo sapiens_hsa001902.64795970
5RNA polymerase_Homo sapiens_hsa030202.51251276
6Ribosome_Homo sapiens_hsa030102.23470216
7One carbon pool by folate_Homo sapiens_hsa006702.20508852
8Mismatch repair_Homo sapiens_hsa034302.18345228
9RNA degradation_Homo sapiens_hsa030182.12934733
10Parkinsons disease_Homo sapiens_hsa050122.10614515
11Homologous recombination_Homo sapiens_hsa034402.09475775
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.05751546
13Basal transcription factors_Homo sapiens_hsa030221.96500253
14RNA transport_Homo sapiens_hsa030131.94881984
15DNA replication_Homo sapiens_hsa030301.86922446
16Asthma_Homo sapiens_hsa053101.86440692
17Allograft rejection_Homo sapiens_hsa053301.85446677
18Non-homologous end-joining_Homo sapiens_hsa034501.72431110
19Nucleotide excision repair_Homo sapiens_hsa034201.68964588
20Cysteine and methionine metabolism_Homo sapiens_hsa002701.67897597
21Spliceosome_Homo sapiens_hsa030401.66572779
22Propanoate metabolism_Homo sapiens_hsa006401.56783978
23Type I diabetes mellitus_Homo sapiens_hsa049401.51233249
24Pyrimidine metabolism_Homo sapiens_hsa002401.50038002
25Base excision repair_Homo sapiens_hsa034101.49373464
26Fanconi anemia pathway_Homo sapiens_hsa034601.46599069
27Autoimmune thyroid disease_Homo sapiens_hsa053201.46077825
28Huntingtons disease_Homo sapiens_hsa050161.45107922
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.43970358
30Primary immunodeficiency_Homo sapiens_hsa053401.42702740
31Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.42519956
32Intestinal immune network for IgA production_Homo sapiens_hsa046721.39765572
33Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.28971005
34Systemic lupus erythematosus_Homo sapiens_hsa053221.26867716
35Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.22160896
36Purine metabolism_Homo sapiens_hsa002301.19230415
37Alzheimers disease_Homo sapiens_hsa050101.19204474
38Pyruvate metabolism_Homo sapiens_hsa006201.09001848
39Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.04856463
40Graft-versus-host disease_Homo sapiens_hsa053321.02163592
41Hematopoietic cell lineage_Homo sapiens_hsa046401.00537766
42Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.00181284
43Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.98943334
44Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.98500004
45Steroid biosynthesis_Homo sapiens_hsa001000.97425817
46Regulation of autophagy_Homo sapiens_hsa041400.96205885
47Pentose and glucuronate interconversions_Homo sapiens_hsa000400.94313721
48Antigen processing and presentation_Homo sapiens_hsa046120.92375906
49Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.89729230
50Rheumatoid arthritis_Homo sapiens_hsa053230.89513442
51Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.89025743
52Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.88543752
53Cyanoamino acid metabolism_Homo sapiens_hsa004600.83512030
54Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.83124645
55Vitamin digestion and absorption_Homo sapiens_hsa049770.80456844
56Glutathione metabolism_Homo sapiens_hsa004800.78040674
57Peroxisome_Homo sapiens_hsa041460.76706511
582-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.75684416
59Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.75130698
60Cardiac muscle contraction_Homo sapiens_hsa042600.75105159
61Nitrogen metabolism_Homo sapiens_hsa009100.74613950
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.73642941
63Caffeine metabolism_Homo sapiens_hsa002320.69162010
64mRNA surveillance pathway_Homo sapiens_hsa030150.68524535
65Sulfur metabolism_Homo sapiens_hsa009200.68408583
66Linoleic acid metabolism_Homo sapiens_hsa005910.66934309
67Metabolic pathways_Homo sapiens_hsa011000.61107510
68Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.57521397
69Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.56836194
70Butanoate metabolism_Homo sapiens_hsa006500.56243270
71Measles_Homo sapiens_hsa051620.54543092
72Jak-STAT signaling pathway_Homo sapiens_hsa046300.53652987
73Carbon metabolism_Homo sapiens_hsa012000.53508310
74Epstein-Barr virus infection_Homo sapiens_hsa051690.52455096
75Phototransduction_Homo sapiens_hsa047440.51885603
76NF-kappa B signaling pathway_Homo sapiens_hsa040640.51813716
77Biosynthesis of amino acids_Homo sapiens_hsa012300.49256455
78T cell receptor signaling pathway_Homo sapiens_hsa046600.48128035
79Cell cycle_Homo sapiens_hsa041100.47733094
80alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.47013433
81Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.46485148
82Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.45227259
83beta-Alanine metabolism_Homo sapiens_hsa004100.43810632
84Alcoholism_Homo sapiens_hsa050340.42364426
85Collecting duct acid secretion_Homo sapiens_hsa049660.41633907
86Transcriptional misregulation in cancer_Homo sapiens_hsa052020.37318629
87Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36673821
88Tryptophan metabolism_Homo sapiens_hsa003800.36356795
89Fatty acid degradation_Homo sapiens_hsa000710.36038011
90Maturity onset diabetes of the young_Homo sapiens_hsa049500.36000257
91Glycerolipid metabolism_Homo sapiens_hsa005610.35270699
92Selenocompound metabolism_Homo sapiens_hsa004500.35177968
93N-Glycan biosynthesis_Homo sapiens_hsa005100.34076134
94Vitamin B6 metabolism_Homo sapiens_hsa007500.33346978
95Fatty acid elongation_Homo sapiens_hsa000620.31211615
96Fat digestion and absorption_Homo sapiens_hsa049750.30925390
97Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.30862106
98Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.28798271
99Ether lipid metabolism_Homo sapiens_hsa005650.28743158
100Drug metabolism - other enzymes_Homo sapiens_hsa009830.27967115

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »