

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 7.63176366 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 7.29952809 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 7.29952809 |
| 4 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.95280356 |
| 5 | respiratory electron transport chain (GO:0022904) | 5.93448010 |
| 6 | electron transport chain (GO:0022900) | 5.81748360 |
| 7 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.38511756 |
| 8 | protein complex biogenesis (GO:0070271) | 5.14320903 |
| 9 | ribosomal small subunit assembly (GO:0000028) | 5.10686246 |
| 10 | proteasome assembly (GO:0043248) | 4.87481915 |
| 11 | viral transcription (GO:0019083) | 4.79117209 |
| 12 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.72621790 |
| 13 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.71830772 |
| 14 | NADH dehydrogenase complex assembly (GO:0010257) | 4.71830772 |
| 15 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.71830772 |
| 16 | translational termination (GO:0006415) | 4.64160312 |
| 17 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.57548515 |
| 18 | cotranslational protein targeting to membrane (GO:0006613) | 4.48529781 |
| 19 | protein targeting to ER (GO:0045047) | 4.43728599 |
| 20 | hydrogen ion transmembrane transport (GO:1902600) | 4.35771324 |
| 21 | chaperone-mediated protein transport (GO:0072321) | 4.29049881 |
| 22 | protein localization to endoplasmic reticulum (GO:0070972) | 4.25261881 |
| 23 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.23430305 |
| 24 | ATP biosynthetic process (GO:0006754) | 4.19684285 |
| 25 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 4.19136065 |
| 26 | GTP biosynthetic process (GO:0006183) | 4.17400036 |
| 27 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 4.17223739 |
| 28 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.14505104 |
| 29 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.14505104 |
| 30 | ribosomal large subunit biogenesis (GO:0042273) | 3.95933590 |
| 31 | proton transport (GO:0015992) | 3.88572220 |
| 32 | translational elongation (GO:0006414) | 3.88446524 |
| 33 | hydrogen transport (GO:0006818) | 3.80994814 |
| 34 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.80972308 |
| 35 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.80588255 |
| 36 | regulation of oxidative phosphorylation (GO:0002082) | 3.80110238 |
| 37 | cytochrome complex assembly (GO:0017004) | 3.79998037 |
| 38 | oxidative phosphorylation (GO:0006119) | 3.79656126 |
| 39 | gonadal mesoderm development (GO:0007506) | 3.73825600 |
| 40 | respiratory chain complex IV assembly (GO:0008535) | 3.71891169 |
| 41 | translation (GO:0006412) | 3.67128029 |
| 42 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.66439313 |
| 43 | regulation of hypersensitivity (GO:0002883) | 3.59796006 |
| 44 | UTP biosynthetic process (GO:0006228) | 3.52490685 |
| 45 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.49207362 |
| 46 | positive regulation of mast cell degranulation (GO:0043306) | 3.49207362 |
| 47 | protein neddylation (GO:0045116) | 3.49142446 |
| 48 | maturation of SSU-rRNA (GO:0030490) | 3.47960626 |
| 49 | regulation of cellular respiration (GO:0043457) | 3.46865175 |
| 50 | viral life cycle (GO:0019058) | 3.39217870 |
| 51 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.39105329 |
| 52 | cellular protein complex disassembly (GO:0043624) | 3.38186140 |
| 53 | translational initiation (GO:0006413) | 3.35351861 |
| 54 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.35190944 |
| 55 | positive regulation of mast cell activation (GO:0033005) | 3.27893555 |
| 56 | base-excision repair, AP site formation (GO:0006285) | 3.25113173 |
| 57 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.23272725 |
| 58 | UTP metabolic process (GO:0046051) | 3.19834560 |
| 59 | DNA deamination (GO:0045006) | 3.19735637 |
| 60 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 3.17534792 |
| 61 | aldehyde catabolic process (GO:0046185) | 3.14069765 |
| 62 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.08621097 |
| 63 | spliceosomal complex assembly (GO:0000245) | 3.02307143 |
| 64 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.02168704 |
| 65 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.99856440 |
| 66 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.98100191 |
| 67 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.97786257 |
| 68 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.97133540 |
| 69 | protein targeting to membrane (GO:0006612) | 2.97062143 |
| 70 | CTP metabolic process (GO:0046036) | 2.94060014 |
| 71 | CTP biosynthetic process (GO:0006241) | 2.94060014 |
| 72 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.93038203 |
| 73 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.93038203 |
| 74 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.93038203 |
| 75 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.91074712 |
| 76 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.90421834 |
| 77 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.90112324 |
| 78 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.90112324 |
| 79 | purine nucleoside monophosphate biosynthetic process (GO:0009127) | 2.84195625 |
| 80 | purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 2.84195625 |
| 81 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.80857011 |
| 82 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.80857011 |
| 83 | RNA phosphodiester bond hydrolysis (GO:0090501) | 2.80256518 |
| 84 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.78616902 |
| 85 | negative regulation of ligase activity (GO:0051352) | 2.78616902 |
| 86 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.78075329 |
| 87 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.78075329 |
| 88 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.77656152 |
| 89 | platelet dense granule organization (GO:0060155) | 2.75604678 |
| 90 | cellular component biogenesis (GO:0044085) | 2.75564304 |
| 91 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.75356514 |
| 92 | one-carbon compound transport (GO:0019755) | 2.74681035 |
| 93 | protein targeting to mitochondrion (GO:0006626) | 2.73625070 |
| 94 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.73349680 |
| 95 | protein complex disassembly (GO:0043241) | 2.73278034 |
| 96 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.72962746 |
| 97 | cellular respiration (GO:0045333) | 2.72496540 |
| 98 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.72211228 |
| 99 | deoxyribose phosphate catabolic process (GO:0046386) | 2.71840660 |
| 100 | protein localization to mitochondrion (GO:0070585) | 2.71823725 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.74332299 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.64822637 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.43699392 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.21721220 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.01259467 |
| 6 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.98960612 |
| 7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.87297055 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.83503867 |
| 9 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.80639862 |
| 10 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.63397526 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.61104283 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.60695557 |
| 13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.48278378 |
| 14 | VDR_22108803_ChIP-Seq_LS180_Human | 2.44413764 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.29854979 |
| 16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.23992494 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.21791669 |
| 18 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.17115828 |
| 19 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.13830111 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.08489154 |
| 21 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.02130359 |
| 22 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.72347987 |
| 23 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.72319543 |
| 24 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.70630819 |
| 25 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.65106414 |
| 26 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.62800633 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.62202821 |
| 28 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.60771762 |
| 29 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.57507436 |
| 30 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.57178592 |
| 31 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.55788135 |
| 32 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.53198166 |
| 33 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.52960178 |
| 34 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.51150232 |
| 35 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.47811416 |
| 36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.46458806 |
| 37 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.46056978 |
| 38 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.45414638 |
| 39 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.36601588 |
| 40 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.34813647 |
| 41 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.34338567 |
| 42 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.34316226 |
| 43 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.30925080 |
| 44 | P300_19829295_ChIP-Seq_ESCs_Human | 1.29080536 |
| 45 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.27640339 |
| 46 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.27306541 |
| 47 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.27306541 |
| 48 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.26851842 |
| 49 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.26620797 |
| 50 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.24046778 |
| 51 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.23722427 |
| 52 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.22920537 |
| 53 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.22814018 |
| 54 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.18222272 |
| 55 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.17699044 |
| 56 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.16738567 |
| 57 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.16336048 |
| 58 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.15635390 |
| 59 | FUS_26573619_Chip-Seq_HEK293_Human | 1.15365001 |
| 60 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.15171535 |
| 61 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14660085 |
| 62 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.14536151 |
| 63 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.14501485 |
| 64 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.12523612 |
| 65 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.10327216 |
| 66 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.10295734 |
| 67 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.10234519 |
| 68 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.09957290 |
| 69 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.07059382 |
| 70 | AR_20517297_ChIP-Seq_VCAP_Human | 1.06965207 |
| 71 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.06462514 |
| 72 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.05387809 |
| 73 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.05302004 |
| 74 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.04796131 |
| 75 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.03683796 |
| 76 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.03556973 |
| 77 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.02242996 |
| 78 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.01993519 |
| 79 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.99550830 |
| 80 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.97695531 |
| 81 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.96622368 |
| 82 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.95713740 |
| 83 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.95528062 |
| 84 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.95528062 |
| 85 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.95264933 |
| 86 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.95171702 |
| 87 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.95171702 |
| 88 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.95007786 |
| 89 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.94888484 |
| 90 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.94845476 |
| 91 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.94493030 |
| 92 | NCOR_22424771_ChIP-Seq_293T_Human | 0.93577959 |
| 93 | GATA3_26560356_Chip-Seq_TH2_Human | 0.93503519 |
| 94 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.92962300 |
| 95 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.92333421 |
| 96 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.90099297 |
| 97 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.88799324 |
| 98 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.87336460 |
| 99 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.87080259 |
| 100 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.86677386 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 4.56333282 |
| 2 | MP0009379_abnormal_foot_pigmentation | 4.36235823 |
| 3 | MP0002837_dystrophic_cardiac_calcinosis | 3.69398574 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.13621963 |
| 5 | MP0001529_abnormal_vocalization | 3.11299689 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.63872104 |
| 7 | MP0003787_abnormal_imprinting | 2.44128388 |
| 8 | MP0006072_abnormal_retinal_apoptosis | 2.36213837 |
| 9 | MP0003646_muscle_fatigue | 2.36037339 |
| 10 | MP0006036_abnormal_mitochondrial_physio | 2.27174244 |
| 11 | MP0005671_abnormal_response_to | 2.22451904 |
| 12 | MP0002102_abnormal_ear_morphology | 2.15761184 |
| 13 | MP0002163_abnormal_gland_morphology | 2.14333702 |
| 14 | MP0003186_abnormal_redox_activity | 2.04518496 |
| 15 | MP0000372_irregular_coat_pigmentation | 2.01301664 |
| 16 | MP0004142_abnormal_muscle_tone | 1.99663823 |
| 17 | MP0008995_early_reproductive_senescence | 1.95156679 |
| 18 | MP0005367_renal/urinary_system_phenotyp | 1.86018984 |
| 19 | MP0000516_abnormal_urinary_system | 1.86018984 |
| 20 | MP0008875_abnormal_xenobiotic_pharmacok | 1.82797759 |
| 21 | MP0005423_abnormal_somatic_nervous | 1.81489095 |
| 22 | MP0008872_abnormal_physiological_respon | 1.81399595 |
| 23 | MP0005075_abnormal_melanosome_morpholog | 1.75490146 |
| 24 | MP0005379_endocrine/exocrine_gland_phen | 1.67761050 |
| 25 | MP0004145_abnormal_muscle_electrophysio | 1.62660170 |
| 26 | MP0009764_decreased_sensitivity_to | 1.61921630 |
| 27 | MP0001919_abnormal_reproductive_system | 1.60827739 |
| 28 | MP0006292_abnormal_olfactory_placode | 1.48554371 |
| 29 | MP0000569_abnormal_digit_pigmentation | 1.43282318 |
| 30 | MP0001905_abnormal_dopamine_level | 1.42879820 |
| 31 | MP0005253_abnormal_eye_physiology | 1.40251467 |
| 32 | MP0001968_abnormal_touch/_nociception | 1.38131665 |
| 33 | MP0005551_abnormal_eye_electrophysiolog | 1.31380507 |
| 34 | MP0008058_abnormal_DNA_repair | 1.31157635 |
| 35 | MP0002090_abnormal_vision | 1.27557204 |
| 36 | MP0002736_abnormal_nociception_after | 1.27081909 |
| 37 | MP0003121_genomic_imprinting | 1.26985445 |
| 38 | MP0003786_premature_aging | 1.26162683 |
| 39 | MP0003195_calcinosis | 1.26121000 |
| 40 | MP0001800_abnormal_humoral_immune | 1.25262950 |
| 41 | MP0003567_abnormal_fetal_cardiomyocyte | 1.25130641 |
| 42 | MP0005389_reproductive_system_phenotype | 1.24253282 |
| 43 | MP0001727_abnormal_embryo_implantation | 1.23205024 |
| 44 | MP0002272_abnormal_nervous_system | 1.22205402 |
| 45 | MP0009046_muscle_twitch | 1.21064055 |
| 46 | MP0001440_abnormal_grooming_behavior | 1.20953253 |
| 47 | MP0005645_abnormal_hypothalamus_physiol | 1.19185903 |
| 48 | MP0003252_abnormal_bile_duct | 1.16700299 |
| 49 | MP0006082_CNS_inflammation | 1.15578687 |
| 50 | MP0001984_abnormal_olfaction | 1.15555494 |
| 51 | MP0002160_abnormal_reproductive_system | 1.14269664 |
| 52 | MP0003880_abnormal_central_pattern | 1.14109806 |
| 53 | MP0002234_abnormal_pharynx_morphology | 1.12608841 |
| 54 | MP0001486_abnormal_startle_reflex | 1.10922932 |
| 55 | MP0009785_altered_susceptibility_to | 1.10756455 |
| 56 | MP0005646_abnormal_pituitary_gland | 1.10615581 |
| 57 | MP0006276_abnormal_autonomic_nervous | 1.10049584 |
| 58 | MP0001756_abnormal_urination | 1.07350694 |
| 59 | MP0005410_abnormal_fertilization | 1.06570983 |
| 60 | MP0002876_abnormal_thyroid_physiology | 1.05714937 |
| 61 | MP0001485_abnormal_pinna_reflex | 1.04995766 |
| 62 | MP0005408_hypopigmentation | 1.03371421 |
| 63 | MP0008789_abnormal_olfactory_epithelium | 1.03124807 |
| 64 | MP0009745_abnormal_behavioral_response | 1.03062076 |
| 65 | MP0002148_abnormal_hypersensitivity_rea | 1.02853478 |
| 66 | MP0005332_abnormal_amino_acid | 1.02312518 |
| 67 | MP0002095_abnormal_skin_pigmentation | 0.99258577 |
| 68 | MP0000639_abnormal_adrenal_gland | 0.97822300 |
| 69 | MP0005386_behavior/neurological_phenoty | 0.94380920 |
| 70 | MP0004924_abnormal_behavior | 0.94380920 |
| 71 | MP0004019_abnormal_vitamin_homeostasis | 0.90541874 |
| 72 | MP0001970_abnormal_pain_threshold | 0.89442083 |
| 73 | MP0005636_abnormal_mineral_homeostasis | 0.88568326 |
| 74 | MP0005377_hearing/vestibular/ear_phenot | 0.87579036 |
| 75 | MP0003878_abnormal_ear_physiology | 0.87579036 |
| 76 | MP0004742_abnormal_vestibular_system | 0.87432589 |
| 77 | MP0006035_abnormal_mitochondrial_morpho | 0.87051941 |
| 78 | MP0003137_abnormal_impulse_conducting | 0.86943266 |
| 79 | MP0002557_abnormal_social/conspecific_i | 0.85070055 |
| 80 | MP0004215_abnormal_myocardial_fiber | 0.84614188 |
| 81 | MP0005394_taste/olfaction_phenotype | 0.83504458 |
| 82 | MP0005499_abnormal_olfactory_system | 0.83504458 |
| 83 | MP0001986_abnormal_taste_sensitivity | 0.83440037 |
| 84 | MP0002229_neurodegeneration | 0.82966097 |
| 85 | MP0005266_abnormal_metabolism | 0.82877271 |
| 86 | MP0005084_abnormal_gallbladder_morpholo | 0.81858237 |
| 87 | MP0002822_catalepsy | 0.81472577 |
| 88 | MP0005174_abnormal_tail_pigmentation | 0.80931768 |
| 89 | MP0009333_abnormal_splenocyte_physiolog | 0.78367164 |
| 90 | MP0004885_abnormal_endolymph | 0.78017781 |
| 91 | MP0002452_abnormal_antigen_presenting | 0.77371395 |
| 92 | MP0000427_abnormal_hair_cycle | 0.76162069 |
| 93 | MP0005000_abnormal_immune_tolerance | 0.75875913 |
| 94 | MP0008775_abnormal_heart_ventricle | 0.75705639 |
| 95 | MP0001873_stomach_inflammation | 0.74967229 |
| 96 | MP0001765_abnormal_ion_homeostasis | 0.73576350 |
| 97 | MP0002723_abnormal_immune_serum | 0.73332992 |
| 98 | MP0003638_abnormal_response/metabolism_ | 0.72515902 |
| 99 | MP0003315_abnormal_perineum_morphology | 0.71829788 |
| 100 | MP0001764_abnormal_homeostasis | 0.71641021 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 6.89078170 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 6.06089430 |
| 3 | Mitochondrial inheritance (HP:0001427) | 5.87142807 |
| 4 | Progressive macrocephaly (HP:0004481) | 5.75637205 |
| 5 | Acute encephalopathy (HP:0006846) | 5.69257276 |
| 6 | Hepatocellular necrosis (HP:0001404) | 5.56043753 |
| 7 | Increased CSF lactate (HP:0002490) | 5.23553783 |
| 8 | Hepatic necrosis (HP:0002605) | 4.92260593 |
| 9 | Congenital, generalized hypertrichosis (HP:0004540) | 4.29628192 |
| 10 | Cerebral edema (HP:0002181) | 4.17381133 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.98318343 |
| 12 | 3-Methylglutaconic aciduria (HP:0003535) | 3.96752950 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 3.75867424 |
| 14 | Leukodystrophy (HP:0002415) | 3.65686342 |
| 15 | Renal Fanconi syndrome (HP:0001994) | 3.50833735 |
| 16 | Respiratory failure (HP:0002878) | 3.36638708 |
| 17 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.35706650 |
| 18 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.35706650 |
| 19 | Exertional dyspnea (HP:0002875) | 3.29162492 |
| 20 | Optic disc pallor (HP:0000543) | 3.25204996 |
| 21 | Increased serum lactate (HP:0002151) | 3.10108179 |
| 22 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.06717272 |
| 23 | Lactic acidosis (HP:0003128) | 3.00569412 |
| 24 | Increased intramyocellular lipid droplets (HP:0012240) | 2.89128686 |
| 25 | Reticulocytopenia (HP:0001896) | 2.83849063 |
| 26 | Exercise intolerance (HP:0003546) | 2.67665412 |
| 27 | Macrocytic anemia (HP:0001972) | 2.65952283 |
| 28 | Stomatitis (HP:0010280) | 2.56675559 |
| 29 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.56280139 |
| 30 | Myokymia (HP:0002411) | 2.52191167 |
| 31 | Abnormality of renal resorption (HP:0011038) | 2.50773349 |
| 32 | Abolished electroretinogram (ERG) (HP:0000550) | 2.48143543 |
| 33 | Increased muscle lipid content (HP:0009058) | 2.43665010 |
| 34 | Molar tooth sign on MRI (HP:0002419) | 2.41714715 |
| 35 | Abnormality of midbrain morphology (HP:0002418) | 2.41714715 |
| 36 | Abnormality of the prostate (HP:0008775) | 2.33665872 |
| 37 | X-linked dominant inheritance (HP:0001423) | 2.33431061 |
| 38 | Pancreatic cysts (HP:0001737) | 2.33183641 |
| 39 | CNS demyelination (HP:0007305) | 2.30973545 |
| 40 | Medial flaring of the eyebrow (HP:0010747) | 2.30109059 |
| 41 | Respiratory difficulties (HP:0002880) | 2.26866197 |
| 42 | Lethargy (HP:0001254) | 2.26548535 |
| 43 | Hypothermia (HP:0002045) | 2.24059098 |
| 44 | Colon cancer (HP:0003003) | 2.19647835 |
| 45 | Abnormality of urine glucose concentration (HP:0011016) | 2.17812415 |
| 46 | Glycosuria (HP:0003076) | 2.17812415 |
| 47 | Hyperphosphaturia (HP:0003109) | 2.08000327 |
| 48 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.00010441 |
| 49 | Woolly hair (HP:0002224) | 1.92995825 |
| 50 | Gait imbalance (HP:0002141) | 1.92817129 |
| 51 | Porencephaly (HP:0002132) | 1.92741073 |
| 52 | Congenital stationary night blindness (HP:0007642) | 1.92481263 |
| 53 | Sclerocornea (HP:0000647) | 1.91700639 |
| 54 | Progressive microcephaly (HP:0000253) | 1.91622471 |
| 55 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.91358057 |
| 56 | Absent/shortened dynein arms (HP:0200106) | 1.89604790 |
| 57 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.89604790 |
| 58 | Congenital primary aphakia (HP:0007707) | 1.88095640 |
| 59 | Male pseudohermaphroditism (HP:0000037) | 1.85053299 |
| 60 | Cleft eyelid (HP:0000625) | 1.84799464 |
| 61 | Obstructive lung disease (HP:0006536) | 1.83109149 |
| 62 | Chronic obstructive pulmonary disease (HP:0006510) | 1.83109149 |
| 63 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.82907499 |
| 64 | Nephrogenic diabetes insipidus (HP:0009806) | 1.82746334 |
| 65 | Sensory axonal neuropathy (HP:0003390) | 1.82738318 |
| 66 | Emotional lability (HP:0000712) | 1.79220792 |
| 67 | Abnormality of the anterior horn cell (HP:0006802) | 1.78750545 |
| 68 | Degeneration of anterior horn cells (HP:0002398) | 1.78750545 |
| 69 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.74601575 |
| 70 | Abnormality of alanine metabolism (HP:0010916) | 1.74601575 |
| 71 | Hyperalaninemia (HP:0003348) | 1.74601575 |
| 72 | Delayed CNS myelination (HP:0002188) | 1.72915941 |
| 73 | Agitation (HP:0000713) | 1.72355720 |
| 74 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.72205146 |
| 75 | Blindness (HP:0000618) | 1.71322321 |
| 76 | Hypomagnesemia (HP:0002917) | 1.68800867 |
| 77 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.67265162 |
| 78 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.66470344 |
| 79 | Gliosis (HP:0002171) | 1.65256402 |
| 80 | Nephronophthisis (HP:0000090) | 1.64595059 |
| 81 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.64181623 |
| 82 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.63306859 |
| 83 | Abnormality of magnesium homeostasis (HP:0004921) | 1.63242540 |
| 84 | Hypoproteinemia (HP:0003075) | 1.62387550 |
| 85 | Pendular nystagmus (HP:0012043) | 1.60527724 |
| 86 | Pallor (HP:0000980) | 1.59961162 |
| 87 | Neoplasm of the adrenal cortex (HP:0100641) | 1.59416051 |
| 88 | Abnormality of male internal genitalia (HP:0000022) | 1.57126245 |
| 89 | Absent thumb (HP:0009777) | 1.55475201 |
| 90 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.55378746 |
| 91 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.55378746 |
| 92 | IgG deficiency (HP:0004315) | 1.54869444 |
| 93 | Rectal fistula (HP:0100590) | 1.53150609 |
| 94 | Rectovaginal fistula (HP:0000143) | 1.53150609 |
| 95 | Abnormality of the renal medulla (HP:0100957) | 1.53131185 |
| 96 | Metaphyseal dysplasia (HP:0100255) | 1.51909409 |
| 97 | Parakeratosis (HP:0001036) | 1.51314293 |
| 98 | Vomiting (HP:0002013) | 1.51047340 |
| 99 | Neoplasm of the adrenal gland (HP:0100631) | 1.49703715 |
| 100 | Pancreatic fibrosis (HP:0100732) | 1.49668262 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K12 | 4.46518105 |
| 2 | VRK2 | 3.24423135 |
| 3 | BMPR2 | 3.17124269 |
| 4 | CDK19 | 2.53270289 |
| 5 | STK16 | 2.27692311 |
| 6 | MAP4K2 | 2.22217819 |
| 7 | ZAK | 2.17276878 |
| 8 | MYLK | 2.13912040 |
| 9 | FRK | 2.12614769 |
| 10 | MST4 | 2.05454397 |
| 11 | SRPK1 | 2.02419640 |
| 12 | TAF1 | 1.94011297 |
| 13 | EIF2AK3 | 1.89100580 |
| 14 | DYRK2 | 1.81027234 |
| 15 | NUAK1 | 1.69132984 |
| 16 | ADRBK2 | 1.67706938 |
| 17 | WNK4 | 1.64586116 |
| 18 | OXSR1 | 1.63315672 |
| 19 | NEK1 | 1.61766320 |
| 20 | EIF2AK1 | 1.61173276 |
| 21 | TLK1 | 1.56149675 |
| 22 | VRK1 | 1.51315861 |
| 23 | TAOK3 | 1.50383356 |
| 24 | DAPK1 | 1.46935240 |
| 25 | ILK | 1.40092423 |
| 26 | GRK1 | 1.32430902 |
| 27 | RIPK4 | 1.27794660 |
| 28 | TXK | 1.25682327 |
| 29 | DAPK3 | 1.24373591 |
| 30 | TEC | 1.20227784 |
| 31 | TIE1 | 1.18978443 |
| 32 | CAMKK2 | 1.16997355 |
| 33 | PBK | 1.14353660 |
| 34 | CSNK1G3 | 1.13144287 |
| 35 | PLK4 | 1.12764193 |
| 36 | TSSK6 | 1.11308443 |
| 37 | NME1 | 1.08711617 |
| 38 | CSNK1G2 | 1.07751178 |
| 39 | INSRR | 1.04613451 |
| 40 | PLK3 | 1.01546615 |
| 41 | ERBB3 | 0.97369630 |
| 42 | MKNK2 | 0.96562744 |
| 43 | CDK8 | 0.95236539 |
| 44 | WNK3 | 0.94965758 |
| 45 | IKBKB | 0.92543967 |
| 46 | CSNK1A1L | 0.90252577 |
| 47 | ABL2 | 0.89580101 |
| 48 | DAPK2 | 0.88920989 |
| 49 | PIK3CG | 0.84237780 |
| 50 | MAP2K7 | 0.83092613 |
| 51 | MINK1 | 0.82523206 |
| 52 | TNK2 | 0.81167449 |
| 53 | PHKG1 | 0.78295997 |
| 54 | PHKG2 | 0.78295997 |
| 55 | CSNK1G1 | 0.78121530 |
| 56 | GRK7 | 0.72654730 |
| 57 | CSF1R | 0.72133616 |
| 58 | LYN | 0.71594523 |
| 59 | PLK2 | 0.70417572 |
| 60 | ITK | 0.68935608 |
| 61 | KIT | 0.67690264 |
| 62 | PNCK | 0.66126919 |
| 63 | ACVR1B | 0.64495029 |
| 64 | GRK5 | 0.64003450 |
| 65 | MAP3K4 | 0.63729616 |
| 66 | AURKB | 0.61216328 |
| 67 | BCKDK | 0.60444461 |
| 68 | ATR | 0.58598051 |
| 69 | PAK3 | 0.58407559 |
| 70 | CSNK2A2 | 0.57935794 |
| 71 | BTK | 0.57540738 |
| 72 | PAK4 | 0.57019700 |
| 73 | EIF2AK2 | 0.56918462 |
| 74 | CHEK2 | 0.56863880 |
| 75 | PRKCG | 0.55723696 |
| 76 | ADRBK1 | 0.55013021 |
| 77 | BMPR1B | 0.53920685 |
| 78 | STK39 | 0.53257781 |
| 79 | PRKCE | 0.53227692 |
| 80 | PDK2 | 0.52858368 |
| 81 | MKNK1 | 0.52777929 |
| 82 | CSNK1A1 | 0.51884487 |
| 83 | NME2 | 0.49521679 |
| 84 | TRIM28 | 0.49252603 |
| 85 | PRKACA | 0.47277521 |
| 86 | SYK | 0.45884077 |
| 87 | PLK1 | 0.45384592 |
| 88 | OBSCN | 0.44501841 |
| 89 | PKN1 | 0.42758876 |
| 90 | DYRK3 | 0.42027554 |
| 91 | CSNK2A1 | 0.41823747 |
| 92 | SCYL2 | 0.41773809 |
| 93 | MAPK13 | 0.40083912 |
| 94 | PRKCD | 0.38958368 |
| 95 | PRKG1 | 0.38603062 |
| 96 | CCNB1 | 0.38428760 |
| 97 | PINK1 | 0.38068320 |
| 98 | TRPM7 | 0.37690607 |
| 99 | MAP2K4 | 0.37007299 |
| 100 | CDK3 | 0.34729396 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.79875675 |
| 2 | Asthma_Homo sapiens_hsa05310 | 4.58231968 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.88082413 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.83553945 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 3.57154697 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.98043605 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.91506161 |
| 8 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.88578571 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.87605101 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.76297395 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 2.58878364 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.37307881 |
| 13 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.36011371 |
| 14 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.25423407 |
| 15 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.23393934 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 2.01141513 |
| 17 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.84023583 |
| 18 | Mismatch repair_Homo sapiens_hsa03430 | 1.81330802 |
| 19 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.71152567 |
| 20 | DNA replication_Homo sapiens_hsa03030 | 1.56028159 |
| 21 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.50651138 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.48500065 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.48437583 |
| 24 | RNA polymerase_Homo sapiens_hsa03020 | 1.40814494 |
| 25 | Viral myocarditis_Homo sapiens_hsa05416 | 1.39303112 |
| 26 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.36749941 |
| 27 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.25750764 |
| 28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.14490388 |
| 29 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.10009505 |
| 30 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.93564537 |
| 31 | Spliceosome_Homo sapiens_hsa03040 | 0.91267699 |
| 32 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.90730999 |
| 33 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.89316119 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.84114329 |
| 35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.84046963 |
| 36 | Phototransduction_Homo sapiens_hsa04744 | 0.83463624 |
| 37 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.82748014 |
| 38 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.82714906 |
| 39 | Base excision repair_Homo sapiens_hsa03410 | 0.80951061 |
| 40 | RNA transport_Homo sapiens_hsa03013 | 0.80943759 |
| 41 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.76013759 |
| 42 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.74314701 |
| 43 | Phagosome_Homo sapiens_hsa04145 | 0.73475966 |
| 44 | Basal transcription factors_Homo sapiens_hsa03022 | 0.72987601 |
| 45 | Leishmaniasis_Homo sapiens_hsa05140 | 0.70813710 |
| 46 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.68887771 |
| 47 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.68196192 |
| 48 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.65393373 |
| 49 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.64674242 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.62758209 |
| 51 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.61417419 |
| 52 | Purine metabolism_Homo sapiens_hsa00230 | 0.59994412 |
| 53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.59130232 |
| 54 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.58204305 |
| 55 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.57159863 |
| 56 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.56546358 |
| 57 | Metabolic pathways_Homo sapiens_hsa01100 | 0.52557821 |
| 58 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.51763368 |
| 59 | Olfactory transduction_Homo sapiens_hsa04740 | 0.51369251 |
| 60 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.51007055 |
| 61 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.50748775 |
| 62 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.46924819 |
| 63 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.46173928 |
| 64 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.44300584 |
| 65 | Tuberculosis_Homo sapiens_hsa05152 | 0.43689671 |
| 66 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.43153266 |
| 67 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.42678886 |
| 68 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.42324333 |
| 69 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.41782839 |
| 70 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.40758822 |
| 71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.36865141 |
| 72 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.36848554 |
| 73 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.36642040 |
| 74 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.35965216 |
| 75 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.34640450 |
| 76 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.34014063 |
| 77 | Legionellosis_Homo sapiens_hsa05134 | 0.33957061 |
| 78 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.30539469 |
| 79 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.30397795 |
| 80 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.29188847 |
| 81 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.29070988 |
| 82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.28951642 |
| 83 | Nicotine addiction_Homo sapiens_hsa05033 | 0.27586764 |
| 84 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.27439441 |
| 85 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.27418200 |
| 86 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.26750397 |
| 87 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.26619892 |
| 88 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.26464023 |
| 89 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.26173982 |
| 90 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.24791406 |
| 91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.23592718 |
| 92 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.23316870 |
| 93 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.22541804 |
| 94 | GABAergic synapse_Homo sapiens_hsa04727 | 0.22445633 |
| 95 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.20715902 |
| 96 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.19437113 |
| 97 | Taste transduction_Homo sapiens_hsa04742 | 0.18857849 |
| 98 | Morphine addiction_Homo sapiens_hsa05032 | 0.17096268 |
| 99 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.13918055 |
| 100 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.13685453 |

