

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein neddylation (GO:0045116) | 7.07931493 |
| 2 | chaperone-mediated protein transport (GO:0072321) | 6.22419096 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.05644489 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 6.05644489 |
| 5 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.99458897 |
| 6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.54317136 |
| 7 | ribosomal small subunit assembly (GO:0000028) | 5.13131666 |
| 8 | DNA deamination (GO:0045006) | 5.12470384 |
| 9 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.93691766 |
| 10 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.93691766 |
| 11 | NADH dehydrogenase complex assembly (GO:0010257) | 4.93691766 |
| 12 | GTP biosynthetic process (GO:0006183) | 4.91495756 |
| 13 | protein complex biogenesis (GO:0070271) | 4.77598313 |
| 14 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.59845900 |
| 15 | UTP biosynthetic process (GO:0006228) | 4.34050832 |
| 16 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.11394765 |
| 17 | respiratory electron transport chain (GO:0022904) | 4.01916604 |
| 18 | chromatin remodeling at centromere (GO:0031055) | 3.99942845 |
| 19 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.97258550 |
| 20 | UTP metabolic process (GO:0046051) | 3.96385854 |
| 21 | electron transport chain (GO:0022900) | 3.94923012 |
| 22 | rRNA modification (GO:0000154) | 3.90462257 |
| 23 | proteasome assembly (GO:0043248) | 3.89462978 |
| 24 | maturation of SSU-rRNA (GO:0030490) | 3.84913185 |
| 25 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.81362624 |
| 26 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.80928409 |
| 27 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.79673376 |
| 28 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.78866417 |
| 29 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.78866417 |
| 30 | CENP-A containing nucleosome assembly (GO:0034080) | 3.75718585 |
| 31 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.73995176 |
| 32 | behavioral response to nicotine (GO:0035095) | 3.63764439 |
| 33 | rRNA methylation (GO:0031167) | 3.56468033 |
| 34 | hydrogen ion transmembrane transport (GO:1902600) | 3.52937556 |
| 35 | CTP biosynthetic process (GO:0006241) | 3.52372834 |
| 36 | CTP metabolic process (GO:0046036) | 3.52372834 |
| 37 | positive regulation of protein homodimerization activity (GO:0090073) | 3.50287934 |
| 38 | ATP biosynthetic process (GO:0006754) | 3.44361045 |
| 39 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.41097685 |
| 40 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.38305320 |
| 41 | termination of RNA polymerase III transcription (GO:0006386) | 3.38305320 |
| 42 | cellular component biogenesis (GO:0044085) | 3.36777112 |
| 43 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.36085172 |
| 44 | rRNA processing (GO:0006364) | 3.23089863 |
| 45 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.18613885 |
| 46 | replication fork processing (GO:0031297) | 3.16958387 |
| 47 | ribosome biogenesis (GO:0042254) | 3.16372798 |
| 48 | rRNA metabolic process (GO:0016072) | 3.15812400 |
| 49 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.14227989 |
| 50 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.14002977 |
| 51 | regulation of immunoglobulin secretion (GO:0051023) | 3.12263618 |
| 52 | cullin deneddylation (GO:0010388) | 3.10209914 |
| 53 | viral transcription (GO:0019083) | 3.10144358 |
| 54 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.08009909 |
| 55 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.08009909 |
| 56 | isotype switching (GO:0045190) | 3.08009909 |
| 57 | respiratory chain complex IV assembly (GO:0008535) | 3.07425152 |
| 58 | proton transport (GO:0015992) | 3.06349225 |
| 59 | translational termination (GO:0006415) | 3.04729224 |
| 60 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.04340004 |
| 61 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.03928851 |
| 62 | ribosomal large subunit biogenesis (GO:0042273) | 3.03789992 |
| 63 | translation (GO:0006412) | 3.02756608 |
| 64 | histone exchange (GO:0043486) | 3.02639340 |
| 65 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.01017963 |
| 66 | hydrogen transport (GO:0006818) | 2.98623938 |
| 67 | regulation of chronic inflammatory response (GO:0002676) | 2.98230790 |
| 68 | protein deneddylation (GO:0000338) | 2.97470461 |
| 69 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.96936372 |
| 70 | protein-cofactor linkage (GO:0018065) | 2.94642590 |
| 71 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.89216046 |
| 72 | DNA replication-independent nucleosome organization (GO:0034724) | 2.89216046 |
| 73 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.87616450 |
| 74 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.86941713 |
| 75 | head development (GO:0060322) | 2.86478644 |
| 76 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.86349555 |
| 77 | ribosomal small subunit biogenesis (GO:0042274) | 2.84518219 |
| 78 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.83578812 |
| 79 | negative regulation of ligase activity (GO:0051352) | 2.83578812 |
| 80 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.82006644 |
| 81 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.82006644 |
| 82 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.82006644 |
| 83 | DNA strand renaturation (GO:0000733) | 2.81848929 |
| 84 | intracellular protein transmembrane import (GO:0044743) | 2.81242110 |
| 85 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.80957182 |
| 86 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.79603757 |
| 87 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.79603757 |
| 88 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.79243604 |
| 89 | cotranslational protein targeting to membrane (GO:0006613) | 2.79076435 |
| 90 | cytochrome complex assembly (GO:0017004) | 2.77362445 |
| 91 | cellular ketone body metabolic process (GO:0046950) | 2.76680242 |
| 92 | protein targeting to ER (GO:0045047) | 2.76579144 |
| 93 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.76153572 |
| 94 | regulation of oxidative phosphorylation (GO:0002082) | 2.75141788 |
| 95 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.74664122 |
| 96 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.74593334 |
| 97 | kinetochore assembly (GO:0051382) | 2.74310584 |
| 98 | piRNA metabolic process (GO:0034587) | 2.73631653 |
| 99 | tRNA metabolic process (GO:0006399) | 2.73033043 |
| 100 | tRNA processing (GO:0008033) | 2.71989283 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.36746143 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.59296083 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.99095883 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.36403090 |
| 5 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.32739458 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.07631873 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.97699563 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.86907244 |
| 9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.86685635 |
| 10 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.82639807 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.80438881 |
| 12 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.74443052 |
| 13 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.56046638 |
| 14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.45235149 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.29876775 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.24921631 |
| 17 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.09042624 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.02634978 |
| 19 | EWS_26573619_Chip-Seq_HEK293_Human | 1.99336612 |
| 20 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.82939596 |
| 21 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.79907497 |
| 22 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.79466686 |
| 23 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.75981713 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.74949520 |
| 25 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.68362836 |
| 26 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.67331641 |
| 27 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.65257097 |
| 28 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.64398581 |
| 29 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.62444729 |
| 30 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.60300456 |
| 31 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.60068538 |
| 32 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.58752548 |
| 33 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.58488712 |
| 34 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.56394715 |
| 35 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.55317644 |
| 36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.52924689 |
| 37 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.47681304 |
| 38 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.43447251 |
| 39 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.40971956 |
| 40 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.40146331 |
| 41 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.37560953 |
| 42 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.37477981 |
| 43 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.35340149 |
| 44 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.35238401 |
| 45 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.34724790 |
| 46 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.30527166 |
| 47 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.29978955 |
| 48 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.29012031 |
| 49 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.26679529 |
| 50 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.20321700 |
| 51 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.19753918 |
| 52 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.16932955 |
| 53 | P300_19829295_ChIP-Seq_ESCs_Human | 1.15502357 |
| 54 | FUS_26573619_Chip-Seq_HEK293_Human | 1.14090502 |
| 55 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.14048196 |
| 56 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.14048196 |
| 57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.14011384 |
| 58 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.13990024 |
| 59 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.13933414 |
| 60 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.12593052 |
| 61 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.12051900 |
| 62 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.12048529 |
| 63 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.12014565 |
| 64 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.09394938 |
| 65 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.04065853 |
| 66 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.02757838 |
| 67 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.01022603 |
| 68 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.01022603 |
| 69 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.00815118 |
| 70 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.00692797 |
| 71 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.00606425 |
| 72 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.98519521 |
| 73 | NCOR_22424771_ChIP-Seq_293T_Human | 0.98232588 |
| 74 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.98154898 |
| 75 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.97348998 |
| 76 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.94993280 |
| 77 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.94814230 |
| 78 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.93985421 |
| 79 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.93521175 |
| 80 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.93419699 |
| 81 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.93109565 |
| 82 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.92399455 |
| 83 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.91437434 |
| 84 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.91199553 |
| 85 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.90091407 |
| 86 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.88122804 |
| 87 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.87745787 |
| 88 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.87625764 |
| 89 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.86252603 |
| 90 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.85642068 |
| 91 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.85422505 |
| 92 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.85055294 |
| 93 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.83952420 |
| 94 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.81239558 |
| 95 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.81229973 |
| 96 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.81192196 |
| 97 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.80075814 |
| 98 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.79809291 |
| 99 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.78659874 |
| 100 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.78612214 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.31243662 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.76486483 |
| 3 | MP0002102_abnormal_ear_morphology | 2.85105545 |
| 4 | MP0003787_abnormal_imprinting | 2.73427454 |
| 5 | MP0004147_increased_porphyrin_level | 2.58094568 |
| 6 | MP0009379_abnormal_foot_pigmentation | 2.49033619 |
| 7 | MP0003693_abnormal_embryo_hatching | 2.39640531 |
| 8 | MP0001348_abnormal_lacrimal_gland | 2.26455007 |
| 9 | MP0003122_maternal_imprinting | 2.23218769 |
| 10 | MP0002653_abnormal_ependyma_morphology | 2.15342098 |
| 11 | MP0001873_stomach_inflammation | 2.01478179 |
| 12 | MP0003718_maternal_effect | 2.00250728 |
| 13 | MP0008872_abnormal_physiological_respon | 1.88595476 |
| 14 | MP0003121_genomic_imprinting | 1.81749804 |
| 15 | MP0005423_abnormal_somatic_nervous | 1.68856304 |
| 16 | MP0002733_abnormal_thermal_nociception | 1.66521849 |
| 17 | MP0006036_abnormal_mitochondrial_physio | 1.65921683 |
| 18 | MP0004957_abnormal_blastocyst_morpholog | 1.60510900 |
| 19 | MP0008058_abnormal_DNA_repair | 1.60393719 |
| 20 | MP0001968_abnormal_touch/_nociception | 1.59996475 |
| 21 | MP0008875_abnormal_xenobiotic_pharmacok | 1.59547594 |
| 22 | MP0002272_abnormal_nervous_system | 1.57660555 |
| 23 | MP0004142_abnormal_muscle_tone | 1.56474240 |
| 24 | MP0001485_abnormal_pinna_reflex | 1.55815781 |
| 25 | MP0004145_abnormal_muscle_electrophysio | 1.54203536 |
| 26 | MP0003786_premature_aging | 1.52313248 |
| 27 | MP0002277_abnormal_respiratory_mucosa | 1.52189636 |
| 28 | MP0001529_abnormal_vocalization | 1.51971726 |
| 29 | MP0002735_abnormal_chemical_nociception | 1.51576692 |
| 30 | MP0003123_paternal_imprinting | 1.49788463 |
| 31 | MP0003880_abnormal_central_pattern | 1.49570634 |
| 32 | MP0010094_abnormal_chromosome_stability | 1.49130911 |
| 33 | MP0004043_abnormal_pH_regulation | 1.47913047 |
| 34 | MP0009745_abnormal_behavioral_response | 1.46317214 |
| 35 | MP0001970_abnormal_pain_threshold | 1.44396407 |
| 36 | MP0002184_abnormal_innervation | 1.43165034 |
| 37 | MP0004742_abnormal_vestibular_system | 1.42563531 |
| 38 | MP0005551_abnormal_eye_electrophysiolog | 1.41170557 |
| 39 | MP0000049_abnormal_middle_ear | 1.39740449 |
| 40 | MP0005084_abnormal_gallbladder_morpholo | 1.37283505 |
| 41 | MP0003646_muscle_fatigue | 1.36380962 |
| 42 | MP0002736_abnormal_nociception_after | 1.35407574 |
| 43 | MP0006072_abnormal_retinal_apoptosis | 1.34562922 |
| 44 | MP0003635_abnormal_synaptic_transmissio | 1.33008925 |
| 45 | MP0004859_abnormal_synaptic_plasticity | 1.25197603 |
| 46 | MP0003011_delayed_dark_adaptation | 1.24961251 |
| 47 | MP0006035_abnormal_mitochondrial_morpho | 1.24868832 |
| 48 | MP0002163_abnormal_gland_morphology | 1.23663209 |
| 49 | MP0001440_abnormal_grooming_behavior | 1.22889103 |
| 50 | MP0001986_abnormal_taste_sensitivity | 1.21957778 |
| 51 | MP0003936_abnormal_reproductive_system | 1.21755188 |
| 52 | MP0008007_abnormal_cellular_replicative | 1.20938089 |
| 53 | MP0000569_abnormal_digit_pigmentation | 1.17290214 |
| 54 | MP0003283_abnormal_digestive_organ | 1.15197908 |
| 55 | MP0006276_abnormal_autonomic_nervous | 1.13183079 |
| 56 | MP0002063_abnormal_learning/memory/cond | 1.11645735 |
| 57 | MP0001919_abnormal_reproductive_system | 1.11230775 |
| 58 | MP0001984_abnormal_olfaction | 1.09568411 |
| 59 | MP0002557_abnormal_social/conspecific_i | 1.09548116 |
| 60 | MP0002138_abnormal_hepatobiliary_system | 1.09295228 |
| 61 | MP0005389_reproductive_system_phenotype | 1.09168140 |
| 62 | MP0001486_abnormal_startle_reflex | 1.08710751 |
| 63 | MP0003937_abnormal_limbs/digits/tail_de | 1.08662904 |
| 64 | MP0001293_anophthalmia | 1.08477940 |
| 65 | MP0002638_abnormal_pupillary_reflex | 1.06881014 |
| 66 | MP0008789_abnormal_olfactory_epithelium | 1.06244265 |
| 67 | MP0001727_abnormal_embryo_implantation | 1.05458056 |
| 68 | MP0002572_abnormal_emotion/affect_behav | 1.05398930 |
| 69 | MP0005645_abnormal_hypothalamus_physiol | 1.04872624 |
| 70 | MP0000955_abnormal_spinal_cord | 1.04306004 |
| 71 | MP0002160_abnormal_reproductive_system | 1.02243978 |
| 72 | MP0000778_abnormal_nervous_system | 1.01740054 |
| 73 | MP0009046_muscle_twitch | 0.98617732 |
| 74 | MP0002752_abnormal_somatic_nervous | 0.98167873 |
| 75 | MP0003195_calcinosis | 0.97980234 |
| 76 | MP0005379_endocrine/exocrine_gland_phen | 0.97829767 |
| 77 | MP0000631_abnormal_neuroendocrine_gland | 0.97550219 |
| 78 | MP0001188_hyperpigmentation | 0.96893933 |
| 79 | MP0008995_early_reproductive_senescence | 0.96649267 |
| 80 | MP0005387_immune_system_phenotype | 0.96520720 |
| 81 | MP0001790_abnormal_immune_system | 0.96520720 |
| 82 | MP0005671_abnormal_response_to | 0.95819064 |
| 83 | MP0003567_abnormal_fetal_cardiomyocyte | 0.94976504 |
| 84 | MP0004133_heterotaxia | 0.92426680 |
| 85 | MP0002006_tumorigenesis | 0.92323530 |
| 86 | MP0001905_abnormal_dopamine_level | 0.91723374 |
| 87 | MP0002064_seizures | 0.91252080 |
| 88 | MP0001881_abnormal_mammary_gland | 0.90559409 |
| 89 | MP0002210_abnormal_sex_determination | 0.88645703 |
| 90 | MP0004885_abnormal_endolymph | 0.88554518 |
| 91 | MP0000685_abnormal_immune_system | 0.86544194 |
| 92 | MP0002734_abnormal_mechanical_nocicepti | 0.84902343 |
| 93 | MP0001835_abnormal_antigen_presentation | 0.84365415 |
| 94 | MP0003890_abnormal_embryonic-extraembry | 0.84223306 |
| 95 | MP0008569_lethality_at_weaning | 0.83973940 |
| 96 | MP0003077_abnormal_cell_cycle | 0.83591812 |
| 97 | MP0000026_abnormal_inner_ear | 0.79739698 |
| 98 | MP0003186_abnormal_redox_activity | 0.78407188 |
| 99 | MP0003315_abnormal_perineum_morphology | 0.75644257 |
| 100 | MP0002751_abnormal_autonomic_nervous | 0.73985948 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.23722395 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.51131686 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.40801994 |
| 4 | Acute encephalopathy (HP:0006846) | 4.40136645 |
| 5 | Increased hepatocellular lipid droplets (HP:0006565) | 4.30668807 |
| 6 | Increased CSF lactate (HP:0002490) | 4.20051301 |
| 7 | Progressive macrocephaly (HP:0004481) | 4.19170433 |
| 8 | Lipid accumulation in hepatocytes (HP:0006561) | 4.06877088 |
| 9 | Renal Fanconi syndrome (HP:0001994) | 3.88501321 |
| 10 | Increased serum pyruvate (HP:0003542) | 3.76007809 |
| 11 | Reticulocytopenia (HP:0001896) | 3.59877370 |
| 12 | Abnormality of the labia minora (HP:0012880) | 3.57665492 |
| 13 | Hepatocellular necrosis (HP:0001404) | 3.45646140 |
| 14 | Cerebral edema (HP:0002181) | 3.26306125 |
| 15 | Myokymia (HP:0002411) | 3.26246021 |
| 16 | Abnormality of glycolysis (HP:0004366) | 3.13366937 |
| 17 | Optic disc pallor (HP:0000543) | 3.12423169 |
| 18 | Pancreatic cysts (HP:0001737) | 3.09236775 |
| 19 | Abnormality of midbrain morphology (HP:0002418) | 3.07683766 |
| 20 | Molar tooth sign on MRI (HP:0002419) | 3.07683766 |
| 21 | Increased serum lactate (HP:0002151) | 3.01407299 |
| 22 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.00374885 |
| 23 | Hepatic necrosis (HP:0002605) | 2.86943506 |
| 24 | Pendular nystagmus (HP:0012043) | 2.78955187 |
| 25 | Increased intramyocellular lipid droplets (HP:0012240) | 2.74241527 |
| 26 | Exertional dyspnea (HP:0002875) | 2.73712804 |
| 27 | Colon cancer (HP:0003003) | 2.64167835 |
| 28 | Abnormality of renal resorption (HP:0011038) | 2.63999265 |
| 29 | True hermaphroditism (HP:0010459) | 2.63078636 |
| 30 | Respiratory difficulties (HP:0002880) | 2.61568214 |
| 31 | Agitation (HP:0000713) | 2.56820962 |
| 32 | Pancreatic fibrosis (HP:0100732) | 2.56044075 |
| 33 | Stomatitis (HP:0010280) | 2.45036483 |
| 34 | 3-Methylglutaconic aciduria (HP:0003535) | 2.44524719 |
| 35 | Abnormality of the pons (HP:0007361) | 2.41400331 |
| 36 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.41051383 |
| 37 | Macrocytic anemia (HP:0001972) | 2.39759470 |
| 38 | Respiratory failure (HP:0002878) | 2.38249735 |
| 39 | Leukodystrophy (HP:0002415) | 2.37332525 |
| 40 | Septo-optic dysplasia (HP:0100842) | 2.36125247 |
| 41 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.35842225 |
| 42 | Nephronophthisis (HP:0000090) | 2.31803976 |
| 43 | Congenital stationary night blindness (HP:0007642) | 2.31250556 |
| 44 | Sclerocornea (HP:0000647) | 2.30917421 |
| 45 | Supernumerary spleens (HP:0009799) | 2.29837517 |
| 46 | Increased muscle lipid content (HP:0009058) | 2.27078179 |
| 47 | Exercise intolerance (HP:0003546) | 2.26784994 |
| 48 | Absent thumb (HP:0009777) | 2.25756254 |
| 49 | Hypoplasia of the pons (HP:0012110) | 2.25206455 |
| 50 | Lactic acidosis (HP:0003128) | 2.22819801 |
| 51 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.19300237 |
| 52 | IgG deficiency (HP:0004315) | 2.18985361 |
| 53 | Chromsome breakage (HP:0040012) | 2.17827381 |
| 54 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.15135413 |
| 55 | Abnormality of DNA repair (HP:0003254) | 2.11625351 |
| 56 | Methylmalonic acidemia (HP:0002912) | 2.10720111 |
| 57 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.07960350 |
| 58 | Abnormality of alanine metabolism (HP:0010916) | 2.07960350 |
| 59 | Hyperalaninemia (HP:0003348) | 2.07960350 |
| 60 | Aplastic anemia (HP:0001915) | 2.05133350 |
| 61 | Lethargy (HP:0001254) | 2.05044258 |
| 62 | Hyperphosphaturia (HP:0003109) | 2.02797473 |
| 63 | Meckel diverticulum (HP:0002245) | 2.02752848 |
| 64 | Increased IgM level (HP:0003496) | 2.02483249 |
| 65 | Cerebral hypomyelination (HP:0006808) | 2.01980972 |
| 66 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.97119647 |
| 67 | Abnormality of the ileum (HP:0001549) | 1.94984987 |
| 68 | Congenital, generalized hypertrichosis (HP:0004540) | 1.94779720 |
| 69 | Abnormal hair whorl (HP:0010721) | 1.94188261 |
| 70 | Male pseudohermaphroditism (HP:0000037) | 1.94011610 |
| 71 | X-linked dominant inheritance (HP:0001423) | 1.91317204 |
| 72 | Methylmalonic aciduria (HP:0012120) | 1.91271243 |
| 73 | Glycosuria (HP:0003076) | 1.91041629 |
| 74 | Abnormality of urine glucose concentration (HP:0011016) | 1.91041629 |
| 75 | Genetic anticipation (HP:0003743) | 1.90932688 |
| 76 | Optic nerve hypoplasia (HP:0000609) | 1.89016697 |
| 77 | Pallor (HP:0000980) | 1.87109852 |
| 78 | Abnormality of the renal collecting system (HP:0004742) | 1.84989978 |
| 79 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.84343122 |
| 80 | Progressive cerebellar ataxia (HP:0002073) | 1.84262051 |
| 81 | Duplicated collecting system (HP:0000081) | 1.83891325 |
| 82 | Multiple enchondromatosis (HP:0005701) | 1.82482817 |
| 83 | Impulsivity (HP:0100710) | 1.82220060 |
| 84 | Type 2 muscle fiber atrophy (HP:0003554) | 1.82043166 |
| 85 | Abnormal number of erythroid precursors (HP:0012131) | 1.81766777 |
| 86 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.80417458 |
| 87 | Narrow forehead (HP:0000341) | 1.78807605 |
| 88 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.77908598 |
| 89 | Anencephaly (HP:0002323) | 1.77750855 |
| 90 | Abnormality of the renal medulla (HP:0100957) | 1.76626253 |
| 91 | Horseshoe kidney (HP:0000085) | 1.74427331 |
| 92 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.74125873 |
| 93 | Abnormality of serum amino acid levels (HP:0003112) | 1.72342323 |
| 94 | Medial flaring of the eyebrow (HP:0010747) | 1.71847628 |
| 95 | Rib fusion (HP:0000902) | 1.69784055 |
| 96 | Increased corneal curvature (HP:0100692) | 1.69205056 |
| 97 | Keratoconus (HP:0000563) | 1.69205056 |
| 98 | Myotonia (HP:0002486) | 1.69068907 |
| 99 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.68553289 |
| 100 | CNS demyelination (HP:0007305) | 1.68388597 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 5.05649453 |
| 2 | VRK2 | 3.95928654 |
| 3 | MST4 | 2.96828700 |
| 4 | EIF2AK1 | 2.88686274 |
| 5 | BUB1 | 2.52155196 |
| 6 | TAF1 | 2.51661183 |
| 7 | EIF2AK3 | 2.30781213 |
| 8 | CASK | 2.14714503 |
| 9 | PBK | 2.13544338 |
| 10 | VRK1 | 2.05945817 |
| 11 | PLK3 | 2.05814198 |
| 12 | NEK1 | 2.03238533 |
| 13 | NUAK1 | 1.98118359 |
| 14 | DYRK2 | 1.93065485 |
| 15 | NME1 | 1.91793414 |
| 16 | PLK4 | 1.87557317 |
| 17 | STK16 | 1.87072267 |
| 18 | SRPK1 | 1.82417947 |
| 19 | TLK1 | 1.82342372 |
| 20 | PLK2 | 1.74626226 |
| 21 | WNK4 | 1.64783896 |
| 22 | ZAK | 1.57802912 |
| 23 | DYRK3 | 1.57363456 |
| 24 | GRK1 | 1.53683230 |
| 25 | CDC7 | 1.51386571 |
| 26 | MKNK2 | 1.49578588 |
| 27 | PNCK | 1.46785619 |
| 28 | WNK3 | 1.46447548 |
| 29 | ADRBK2 | 1.44532996 |
| 30 | EIF2AK2 | 1.29801076 |
| 31 | MAP3K9 | 1.19388527 |
| 32 | TRIM28 | 1.12811343 |
| 33 | MINK1 | 1.12790997 |
| 34 | ALK | 1.09790307 |
| 35 | SIK2 | 1.04970417 |
| 36 | PDK2 | 1.00232868 |
| 37 | CDK8 | 0.95000194 |
| 38 | PLK1 | 0.93708732 |
| 39 | OXSR1 | 0.92701866 |
| 40 | CSNK1G2 | 0.92517747 |
| 41 | MAP3K4 | 0.91249092 |
| 42 | WEE1 | 0.90742907 |
| 43 | FRK | 0.85490943 |
| 44 | CSNK1G3 | 0.83300276 |
| 45 | MKNK1 | 0.82105013 |
| 46 | PIK3CA | 0.81271965 |
| 47 | NME2 | 0.78120833 |
| 48 | GRK5 | 0.77774550 |
| 49 | MAPK13 | 0.77541501 |
| 50 | CSNK1A1L | 0.76345452 |
| 51 | PRKCG | 0.75299804 |
| 52 | BMPR1B | 0.75075150 |
| 53 | TTK | 0.73724161 |
| 54 | ATR | 0.72986193 |
| 55 | CSNK1E | 0.72754305 |
| 56 | AURKB | 0.69933520 |
| 57 | TAOK3 | 0.68147749 |
| 58 | PHKG2 | 0.67855437 |
| 59 | PHKG1 | 0.67855437 |
| 60 | ADRBK1 | 0.67814766 |
| 61 | INSRR | 0.67699245 |
| 62 | CSNK2A2 | 0.66602585 |
| 63 | BCR | 0.66063412 |
| 64 | CSNK1G1 | 0.65629931 |
| 65 | TNIK | 0.62952183 |
| 66 | TXK | 0.61349925 |
| 67 | MARK1 | 0.61096125 |
| 68 | STK39 | 0.60696105 |
| 69 | MAP4K2 | 0.60574804 |
| 70 | PASK | 0.59161462 |
| 71 | MAPKAPK5 | 0.57968748 |
| 72 | AKT3 | 0.56100548 |
| 73 | NTRK2 | 0.54888863 |
| 74 | CSNK2A1 | 0.52993606 |
| 75 | EPHB2 | 0.52142107 |
| 76 | GRK7 | 0.51937203 |
| 77 | DAPK3 | 0.51589568 |
| 78 | SIK3 | 0.50713753 |
| 79 | EPHA4 | 0.50039997 |
| 80 | STK4 | 0.45415716 |
| 81 | ERBB3 | 0.44274946 |
| 82 | TYRO3 | 0.43283712 |
| 83 | PINK1 | 0.42595285 |
| 84 | TIE1 | 0.42299693 |
| 85 | PRKACA | 0.40292324 |
| 86 | ATM | 0.40221967 |
| 87 | AURKA | 0.38428620 |
| 88 | NTRK3 | 0.37231139 |
| 89 | CAMK2A | 0.36348041 |
| 90 | CCNB1 | 0.35246793 |
| 91 | PRKCI | 0.34706870 |
| 92 | CSNK1A1 | 0.34353103 |
| 93 | DAPK1 | 0.33542879 |
| 94 | CHEK1 | 0.32971101 |
| 95 | DYRK1A | 0.32709020 |
| 96 | CHEK2 | 0.31896861 |
| 97 | ILK | 0.30917346 |
| 98 | PRKDC | 0.29348179 |
| 99 | CDK14 | 0.29160322 |
| 100 | KIT | 0.29117949 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.10763570 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.80843478 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.57007820 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.46644676 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.31565356 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.89172508 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.80855849 |
| 8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.57959327 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.54000385 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.41406738 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.37255238 |
| 12 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.26246387 |
| 13 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.19585413 |
| 14 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.13973664 |
| 15 | Mismatch repair_Homo sapiens_hsa03430 | 1.94967572 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.88479671 |
| 17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.84828166 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.84611386 |
| 19 | Asthma_Homo sapiens_hsa05310 | 1.84603404 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.73517414 |
| 21 | RNA transport_Homo sapiens_hsa03013 | 1.63257002 |
| 22 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.57220002 |
| 23 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.56730050 |
| 24 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.51629913 |
| 25 | DNA replication_Homo sapiens_hsa03030 | 1.50739745 |
| 26 | Spliceosome_Homo sapiens_hsa03040 | 1.43331322 |
| 27 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.41619352 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.35886638 |
| 29 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.32721780 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.29496902 |
| 31 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.26061981 |
| 32 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.20321565 |
| 33 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.19376484 |
| 34 | Sulfur relay system_Homo sapiens_hsa04122 | 1.10265901 |
| 35 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.04155292 |
| 36 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.03318921 |
| 37 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.02430934 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.01630323 |
| 39 | Phototransduction_Homo sapiens_hsa04744 | 0.99859596 |
| 40 | Nicotine addiction_Homo sapiens_hsa05033 | 0.99156773 |
| 41 | Peroxisome_Homo sapiens_hsa04146 | 0.96567294 |
| 42 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.96197155 |
| 43 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.93944797 |
| 44 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.90571788 |
| 45 | Allograft rejection_Homo sapiens_hsa05330 | 0.87813851 |
| 46 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.86996338 |
| 47 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.85645988 |
| 48 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.82183092 |
| 49 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.80635237 |
| 50 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.78770241 |
| 51 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.76862305 |
| 52 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.76523334 |
| 53 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.76048868 |
| 54 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.70071530 |
| 55 | Base excision repair_Homo sapiens_hsa03410 | 0.69649204 |
| 56 | Olfactory transduction_Homo sapiens_hsa04740 | 0.67307125 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.64788839 |
| 58 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.63291836 |
| 59 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.63227272 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62996762 |
| 61 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.62783726 |
| 62 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.57642728 |
| 63 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.56491415 |
| 64 | Taste transduction_Homo sapiens_hsa04742 | 0.56178122 |
| 65 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.53284296 |
| 66 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.51460614 |
| 67 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.50906420 |
| 68 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.50096797 |
| 69 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.49104908 |
| 70 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.45346406 |
| 71 | Retinol metabolism_Homo sapiens_hsa00830 | 0.44803026 |
| 72 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.43350689 |
| 73 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.41965950 |
| 74 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.38214395 |
| 75 | Cell cycle_Homo sapiens_hsa04110 | 0.35588252 |
| 76 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.34953669 |
| 77 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.34636448 |
| 78 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.32638331 |
| 79 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.31606332 |
| 80 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.31480461 |
| 81 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.30611784 |
| 82 | Morphine addiction_Homo sapiens_hsa05032 | 0.29001550 |
| 83 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.27909043 |
| 84 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.26816152 |
| 85 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.25109427 |
| 86 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.25065236 |
| 87 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.24707167 |
| 88 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.22588415 |
| 89 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.21158150 |
| 90 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.19454442 |
| 91 | GABAergic synapse_Homo sapiens_hsa04727 | 0.18185762 |
| 92 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.17722647 |
| 93 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.17417163 |
| 94 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.15927437 |
| 95 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.15845122 |
| 96 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.14245212 |
| 97 | Insulin secretion_Homo sapiens_hsa04911 | 0.13626532 |
| 98 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.12414312 |
| 99 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.12242721 |
| 100 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.11940122 |

