HTATIP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)5.00953967
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.00953967
3L-phenylalanine metabolic process (GO:0006558)4.98800637
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.98800637
5neutrophil activation involved in immune response (GO:0002283)4.87823231
6aromatic amino acid family catabolic process (GO:0009074)4.60649931
7triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.51886684
8cysteine metabolic process (GO:0006534)4.39923646
9indole-containing compound catabolic process (GO:0042436)4.29421127
10indolalkylamine catabolic process (GO:0046218)4.29421127
11tryptophan catabolic process (GO:0006569)4.29421127
12tryptophan metabolic process (GO:0006568)4.20798830
13protein carboxylation (GO:0018214)4.18775409
14peptidyl-glutamic acid carboxylation (GO:0017187)4.18775409
15urea metabolic process (GO:0019627)4.15063533
16urea cycle (GO:0000050)4.15063533
17polyketide metabolic process (GO:0030638)4.13635184
18doxorubicin metabolic process (GO:0044598)4.13635184
19daunorubicin metabolic process (GO:0044597)4.13635184
20kynurenine metabolic process (GO:0070189)4.13132742
21aldehyde catabolic process (GO:0046185)4.11683104
22high-density lipoprotein particle remodeling (GO:0034375)4.07057942
23sulfur amino acid catabolic process (GO:0000098)4.05305726
24bile acid biosynthetic process (GO:0006699)3.99203758
25nitrogen cycle metabolic process (GO:0071941)3.88872342
26fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.84885163
27regulation of protein activation cascade (GO:2000257)3.83245091
28glyoxylate metabolic process (GO:0046487)3.79123050
29amino-acid betaine metabolic process (GO:0006577)3.78248443
30phospholipid efflux (GO:0033700)3.76909903
31regulation of cholesterol esterification (GO:0010872)3.74803362
32negative regulation of fibrinolysis (GO:0051918)3.74410862
33regulation of triglyceride catabolic process (GO:0010896)3.73714758
34epoxygenase P450 pathway (GO:0019373)3.71631226
35complement activation, alternative pathway (GO:0006957)3.70725469
36regulation of complement activation (GO:0030449)3.65170420
37aminoglycoside antibiotic metabolic process (GO:0030647)3.60170562
38plasma lipoprotein particle clearance (GO:0034381)3.58807216
39aromatic amino acid family metabolic process (GO:0009072)3.55259672
40plasma lipoprotein particle remodeling (GO:0034369)3.53404256
41protein-lipid complex remodeling (GO:0034368)3.53404256
42macromolecular complex remodeling (GO:0034367)3.53404256
43cyclooxygenase pathway (GO:0019371)3.51413119
44serine family amino acid catabolic process (GO:0009071)3.50958498
45reverse cholesterol transport (GO:0043691)3.50703056
46alpha-linolenic acid metabolic process (GO:0036109)3.46747989
47regulation of fibrinolysis (GO:0051917)3.44606643
48cofactor catabolic process (GO:0051187)3.44573938
49homocysteine metabolic process (GO:0050667)3.42799897
50tyrosine metabolic process (GO:0006570)3.42393208
51lysine metabolic process (GO:0006553)3.40129587
52lysine catabolic process (GO:0006554)3.40129587
53ethanol oxidation (GO:0006069)3.38229943
54bile acid metabolic process (GO:0008206)3.33818698
55glycoside metabolic process (GO:0016137)3.31905818
56glycolipid catabolic process (GO:0019377)3.28488589
57glycosphingolipid catabolic process (GO:0046479)3.27192875
58positive regulation of lipoprotein lipase activity (GO:0051006)3.23878706
59positive regulation of triglyceride lipase activity (GO:0061365)3.23878706
60drug catabolic process (GO:0042737)3.23489578
61cholesterol efflux (GO:0033344)3.21206305
62plasma lipoprotein particle assembly (GO:0034377)3.19539568
63cellular glucuronidation (GO:0052695)3.16091848
64carnitine metabolic process (GO:0009437)3.15610026
65benzene-containing compound metabolic process (GO:0042537)3.13239314
66NAD biosynthetic process (GO:0009435)3.13121216
67fibrinolysis (GO:0042730)3.13117341
68nicotinamide nucleotide biosynthetic process (GO:0019359)3.12615678
69pyridine nucleotide biosynthetic process (GO:0019363)3.12615678
70indolalkylamine metabolic process (GO:0006586)3.10374578
71negative regulation of cholesterol transport (GO:0032375)3.09461783
72negative regulation of sterol transport (GO:0032372)3.09461783
73alpha-amino acid catabolic process (GO:1901606)3.08067614
74acylglycerol homeostasis (GO:0055090)3.07476094
75triglyceride homeostasis (GO:0070328)3.07476094
76serine family amino acid metabolic process (GO:0009069)3.07126061
77very-low-density lipoprotein particle assembly (GO:0034379)3.06813795
78cellular biogenic amine catabolic process (GO:0042402)3.06313906
79amine catabolic process (GO:0009310)3.06313906
80uronic acid metabolic process (GO:0006063)3.05853979
81glucuronate metabolic process (GO:0019585)3.05853979
82glycine metabolic process (GO:0006544)3.05224970
83peptide catabolic process (GO:0043171)3.00230319
84xenobiotic catabolic process (GO:0042178)3.00082256
85bile acid and bile salt transport (GO:0015721)2.99976181
86positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.99311416
87positive regulation of Cdc42 GTPase activity (GO:0043089)2.98229423
88pyrimidine nucleoside catabolic process (GO:0046135)2.95231629
89acute-phase response (GO:0006953)2.93210924
90positive regulation of lipid catabolic process (GO:0050996)2.93173467
91pentose-phosphate shunt (GO:0006098)2.92446911
92plasma lipoprotein particle organization (GO:0071827)2.91812658
93low-density lipoprotein particle remodeling (GO:0034374)2.90970318
94ethanol metabolic process (GO:0006067)2.90608930
95protein maturation by protein folding (GO:0022417)2.90409807
96flavonoid metabolic process (GO:0009812)2.90138056
97primary alcohol catabolic process (GO:0034310)2.89749817
98complement activation, classical pathway (GO:0006958)2.89297262
99response to nitrosative stress (GO:0051409)2.87204086
100complement activation (GO:0006956)2.86369354
101serine family amino acid biosynthetic process (GO:0009070)2.86281000
102exogenous drug catabolic process (GO:0042738)2.85831679
103protein-lipid complex assembly (GO:0065005)2.85687588
104blood coagulation, intrinsic pathway (GO:0007597)2.84175457
105cellular amino acid catabolic process (GO:0009063)2.82956892
106NADPH regeneration (GO:0006740)2.82864690
107protein activation cascade (GO:0072376)2.81894649
108alkaloid metabolic process (GO:0009820)2.81703174
109arginine metabolic process (GO:0006525)2.81684030
110imidazole-containing compound metabolic process (GO:0052803)2.81229393
111heme metabolic process (GO:0042168)2.79786969
112fatty acid oxidation (GO:0019395)2.79017473
113phospholipid homeostasis (GO:0055091)2.78923490
114oligosaccharide catabolic process (GO:0009313)2.76435122
115cholesterol homeostasis (GO:0042632)2.76244433
116neutrophil activation (GO:0042119)2.68921908
117antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.65822681
118granulocyte activation (GO:0036230)2.65538512
119antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.64012515
120antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.61267018
121ceramide catabolic process (GO:0046514)2.57353629
122response to peptidoglycan (GO:0032494)2.54619613
123nucleobase-containing small molecule interconversion (GO:0015949)2.54251188
124negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.53365377
125Golgi transport vesicle coating (GO:0048200)2.52947209
126COPI coating of Golgi vesicle (GO:0048205)2.52947209
127NIK/NF-kappaB signaling (GO:0038061)2.51260707
128NADH metabolic process (GO:0006734)2.48802304
129progesterone metabolic process (GO:0042448)2.48160700
130immunoglobulin mediated immune response (GO:0016064)2.45600624
131regulation of superoxide anion generation (GO:0032928)2.45094257
132glucose catabolic process (GO:0006007)2.44423825
133antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.43938873
134lipoxygenase pathway (GO:0019372)2.43397975
135proteasome assembly (GO:0043248)2.42330385
136positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.40563013
137regulation of metalloenzyme activity (GO:0048552)2.39078741
138fat-soluble vitamin biosynthetic process (GO:0042362)2.36755303
139B cell mediated immunity (GO:0019724)2.35920015
140membrane lipid catabolic process (GO:0046466)2.35547829
141negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.35032265
142regulation of cellular amino acid metabolic process (GO:0006521)2.34003091
143antigen processing and presentation of endogenous antigen (GO:0019883)2.33297938
144regulation of vitamin metabolic process (GO:0030656)2.32614192
145nucleotide-sugar biosynthetic process (GO:0009226)2.31766942
146pentose metabolic process (GO:0019321)2.29197506
147GDP-mannose metabolic process (GO:0019673)2.28217951
148antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.25244106
149negative regulation of protein localization to plasma membrane (GO:1903077)2.24656023
150sphingolipid catabolic process (GO:0030149)2.23900396
151NADP metabolic process (GO:0006739)2.23602937
152lipopolysaccharide-mediated signaling pathway (GO:0031663)2.22569236
153arachidonic acid metabolic process (GO:0019369)2.20724126
154regulation of RIG-I signaling pathway (GO:0039535)2.20353957
155antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.19791307
156glucose 6-phosphate metabolic process (GO:0051156)2.19613123
157ribosome assembly (GO:0042255)2.17391415
158cellular response to cadmium ion (GO:0071276)2.16105710
159positive regulation of cellular amine metabolic process (GO:0033240)2.15970959
160detection of other organism (GO:0098543)2.14625988
161negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.14013612
162regulation of interferon-beta biosynthetic process (GO:0045357)2.13318093
163pyrimidine-containing compound salvage (GO:0008655)2.12247312
164pyrimidine nucleoside salvage (GO:0043097)2.12247312
165cellular response to arsenic-containing substance (GO:0071243)2.12228712
166nucleoside diphosphate biosynthetic process (GO:0009133)2.11306601
167detection of bacterium (GO:0016045)2.09089565
168positive regulation by symbiont of host defense response (GO:0052509)2.08254547
169modulation by symbiont of host defense response (GO:0052031)2.08254547
170modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.08254547
171modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.08254547
172positive regulation by organism of defense response of other organism involved in symbiotic interact2.08254547
173modulation by symbiont of host immune response (GO:0052553)2.08254547
174hormone catabolic process (GO:0042447)2.07189538
175positive regulation of leukocyte degranulation (GO:0043302)2.06743422
176regulation of podosome assembly (GO:0071801)2.06584032
177thrombin receptor signaling pathway (GO:0070493)2.05296749
178negative regulation of hemostasis (GO:1900047)2.03372706
179negative regulation of blood coagulation (GO:0030195)2.03372706
180pinocytosis (GO:0006907)2.02504627
181mitochondrial calcium ion transport (GO:0006851)2.01997291
182negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.01697028

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse7.26639838
2RXR_22158963_ChIP-Seq_LIVER_Mouse5.03574358
3PPARA_22158963_ChIP-Seq_LIVER_Mouse4.54829990
4EGR1_23403033_ChIP-Seq_LIVER_Mouse4.22291547
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.07710750
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.79751757
7* LXR_22158963_ChIP-Seq_LIVER_Mouse3.60299383
8IRF8_22096565_ChIP-ChIP_GC-B_Human3.52762310
9FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.97642273
10CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.88366486
11GATA1_22025678_ChIP-Seq_K562_Human2.62598520
12* IRF8_21731497_ChIP-ChIP_J774_Mouse2.33916797
13SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.30100468
14EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.20541887
15IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.12773938
16BP1_19119308_ChIP-ChIP_Hs578T_Human2.09212280
17TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.98709444
18IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.95579617
19STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.92974938
20NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.92288809
21TP63_17297297_ChIP-ChIP_HaCaT_Human1.88267042
22TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.85158769
23NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.81245217
24HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.79464531
25MYB_21317192_ChIP-Seq_ERMYB_Mouse1.69397663
26NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.64143947
27ELF1_17652178_ChIP-ChIP_JURKAT_Human1.57775698
28SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.55800285
29* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.55503513
30IRF8_27001747_Chip-Seq_BMDM_Mouse1.54242696
31RARG_19884340_ChIP-ChIP_MEFs_Mouse1.53566357
32RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.49644969
33* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.48047176
34RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.46138824
35SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.43121376
36KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.38583765
37SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.36201731
38THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.35913196
39* SOX2_20726797_ChIP-Seq_SW620_Human1.35881420
40NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.35533931
41EGR1_19374776_ChIP-ChIP_THP-1_Human1.35426312
42FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.35395475
43NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.31536102
44* GATA6_25053715_ChIP-Seq_YYC3_Human1.30285838
45BRD4_27068464_Chip-Seq_AML-cells_Mouse1.30157248
46TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.27943295
47SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.27936275
48SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.27936275
49GATA2_21666600_ChIP-Seq_HMVEC_Human1.25131583
50KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.24924695
51SPI1_23127762_ChIP-Seq_K562_Human1.23951094
52FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.23068206
53SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.22342302
54ELK3_25401928_ChIP-Seq_HUVEC_Human1.22137398
55STAT4_19710469_ChIP-ChIP_TH1__Mouse1.21987723
56FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.20467650
57STAT3_1855785_ChIP-Seq_MESCs_Mouse1.18747038
58JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.17927356
59* RACK7_27058665_Chip-Seq_MCF-7_Human1.16172364
60CREB1_15753290_ChIP-ChIP_HEK293T_Human1.15997012
61* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.15124379
62PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.14291268
63KLF4_18555785_ChIP-Seq_MESCs_Mouse1.14277008
64SRF_21415370_ChIP-Seq_HL-1_Mouse1.14230413
65KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.13129601
66GABP_17652178_ChIP-ChIP_JURKAT_Human1.12504245
67GATA1_22383799_ChIP-Seq_G1ME_Mouse1.10683487
68HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.10482154
69SPI1_23547873_ChIP-Seq_NB4_Human1.10006039
70NELFA_20434984_ChIP-Seq_ESCs_Mouse1.09708524
71NCOR1_26117541_ChIP-Seq_K562_Human1.08183712
72ESR2_21235772_ChIP-Seq_MCF-7_Human1.07200200
73CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.07098860
74E2F7_22180533_ChIP-Seq_HELA_Human1.06370531
75CDX2_20551321_ChIP-Seq_CACO-2_Human1.04900292
76CLOCK_20551151_ChIP-Seq_293T_Human1.03933637
77PPAR_26484153_Chip-Seq_NCI-H1993_Human1.03421173
78MYC_18555785_ChIP-Seq_MESCs_Mouse1.02970807
79AR_21909140_ChIP-Seq_LNCAP_Human1.02928057
80STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.02876816
81GATA2_22383799_ChIP-Seq_G1ME_Mouse1.02053316
82HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.01880488
83ZNF263_19887448_ChIP-Seq_K562_Human1.01621305
84CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00650692
85SRY_22984422_ChIP-ChIP_TESTIS_Rat0.99017609
86ZFX_18555785_ChIP-Seq_MESCs_Mouse0.97994913
87GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.97648554
88TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97399252
89LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.97139424
90MYC_19030024_ChIP-ChIP_MESCs_Mouse0.96851275
91GATA4_25053715_ChIP-Seq_YYC3_Human0.95635547
92* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.95514912
93RUNX1_22412390_ChIP-Seq_EML_Mouse0.94966734
94CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93941405
95LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.93852034
96DCP1A_22483619_ChIP-Seq_HELA_Human0.93602741
97MAF_26560356_Chip-Seq_TH1_Human0.93258487
98CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.92831990
99GATA1_19941827_ChIP-Seq_MEL_Mouse0.91904849
100PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.89991084
101TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.88596425
102E2F1_18555785_ChIP-Seq_MESCs_Mouse0.87833870
103EST1_17652178_ChIP-ChIP_JURKAT_Human0.87772481
104SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87691470
105HOXB4_20404135_ChIP-ChIP_EML_Mouse0.87651070
106TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.87395446
107ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.86523766
108PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86461840
109TFEB_21752829_ChIP-Seq_HELA_Human0.86236308
110MYB_26560356_Chip-Seq_TH1_Human0.86162635
111MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.85831843
112TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.84996397
113PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.83377280
114MYB_26560356_Chip-Seq_TH2_Human0.82837047
115CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.82030795
116* SOX2_27498859_Chip-Seq_STOMACH_Mouse0.81594981
117SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.81500481
118MYC_18358816_ChIP-ChIP_MESCs_Mouse0.80843620
119PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.80405625
120PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.79621869
121ETS1_20019798_ChIP-Seq_JURKAT_Human0.79299688
122RXRA_24833708_ChIP-Seq_LIVER_Mouse0.77890757
123STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.76944102
124SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.76345095
125CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.76302049
126PU_27001747_Chip-Seq_BMDM_Mouse0.75480499
127VDR_23849224_ChIP-Seq_CD4+_Human0.75389542
128ATF3_27146783_Chip-Seq_COLON_Human0.75368246
129SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.74886453
130ERG_20887958_ChIP-Seq_HPC-7_Mouse0.74782472
131BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.73397432
132* HNF4A_19822575_ChIP-Seq_HepG2_Human0.72499014

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system5.46215505
2MP0005360_urolithiasis5.06326655
3MP0005085_abnormal_gallbladder_physiolo4.29362330
4MP0005365_abnormal_bile_salt4.16413180
5MP0003806_abnormal_nucleotide_metabolis4.03503647
6MP0008875_abnormal_xenobiotic_pharmacok3.80284026
7MP0009840_abnormal_foam_cell3.13603326
8MP0005083_abnormal_biliary_tract2.73360466
9MP0010329_abnormal_lipoprotein_level2.53780580
10MP0003191_abnormal_cellular_cholesterol2.52606391
11MP0003656_abnormal_erythrocyte_physiolo2.48908698
12MP0003252_abnormal_bile_duct2.39788121
13MP0003186_abnormal_redox_activity2.30024434
14MP0003195_calcinosis2.28181779
15MP0005332_abnormal_amino_acid2.10349063
16MP0002877_abnormal_melanocyte_morpholog1.97873775
17MP0003436_decreased_susceptibility_to1.97074428
18MP0000609_abnormal_liver_physiology1.92852772
19MP0001666_abnormal_nutrient_absorption1.89876724
20MP0005319_abnormal_enzyme/_coenzyme1.81631928
21MP0001835_abnormal_antigen_presentation1.81282418
22MP0009785_altered_susceptibility_to1.78827240
23MP0008004_abnormal_stomach_pH1.77945316
24MP0010352_gastrointestinal_tract_polyps1.71328326
25MP0002138_abnormal_hepatobiliary_system1.70609494
26MP0005058_abnormal_lysosome_morphology1.63585574
27MP0001764_abnormal_homeostasis1.60124107
28MP0005464_abnormal_platelet_physiology1.59236424
29MP0009764_decreased_sensitivity_to1.59091941
30MP0003566_abnormal_cell_adhesion1.58925695
31MP0004019_abnormal_vitamin_homeostasis1.58496894
32MP0002118_abnormal_lipid_homeostasis1.55593342
33MP0008469_abnormal_protein_level1.51441592
34MP0008260_abnormal_autophagy1.49088725
35MP0005584_abnormal_enzyme/coenzyme_acti1.44988449
36MP0003453_abnormal_keratinocyte_physiol1.44747549
37MP0005025_abnormal_response_to1.43771070
38MP0009643_abnormal_urine_homeostasis1.42216336
39MP0003724_increased_susceptibility_to1.41377925
40MP0002148_abnormal_hypersensitivity_rea1.40702768
41MP0000465_gastrointestinal_hemorrhage1.40562695
42MP0002419_abnormal_innate_immunity1.36821593
43MP0005451_abnormal_body_composition1.35916270
44MP0000685_abnormal_immune_system1.35770537
45MP0001853_heart_inflammation1.31228539
46MP0006082_CNS_inflammation1.30480579
47MP0000604_amyloidosis1.27878680
48MP0005636_abnormal_mineral_homeostasis1.26593511
49MP0005501_abnormal_skin_physiology1.25532592
50MP0004947_skin_inflammation1.25355975
51MP0000490_abnormal_crypts_of1.22740801
52MP0004264_abnormal_extraembryonic_tissu1.20998672
53MP0006036_abnormal_mitochondrial_physio1.19578784
54MP0009763_increased_sensitivity_to1.19253964
55MP0003866_abnormal_defecation1.17143880
56MP0005000_abnormal_immune_tolerance1.16891409
57MP0005165_increased_susceptibility_to1.16723539
58MP0001845_abnormal_inflammatory_respons1.16718870
59MP0009697_abnormal_copulation1.16013735
60MP0000598_abnormal_liver_morphology1.15792781
61MP0005671_abnormal_response_to1.11436645
62MP0001800_abnormal_humoral_immune1.10462830
63MP0004147_increased_porphyrin_level1.08934067
64MP0001790_abnormal_immune_system1.05022241
65MP0005387_immune_system_phenotype1.05022241
66MP0002723_abnormal_immune_serum1.02541099
67MP0002166_altered_tumor_susceptibility1.02054427
68MP0003172_abnormal_lysosome_physiology1.02042807
69MP0003705_abnormal_hypodermis_morpholog1.00641913
70MP0002452_abnormal_antigen_presenting1.00615089
71MP0000343_altered_response_to0.99678524
72MP0004957_abnormal_blastocyst_morpholog0.99473435
73MP0001756_abnormal_urination0.99234950
74MP0001873_stomach_inflammation0.99073634
75MP0003448_altered_tumor_morphology0.97117178
76MP0002132_abnormal_respiratory_system0.94639019
77MP0005408_hypopigmentation0.93655508
78MP0001533_abnormal_skeleton_physiology0.93407307
79MP0009765_abnormal_xenobiotic_induced0.93079548
80MP0003183_abnormal_peptide_metabolism0.90762879
81MP0002405_respiratory_system_inflammati0.88973411
82MP0001216_abnormal_epidermal_layer0.88682275
83MP0004782_abnormal_surfactant_physiolog0.88553756
84MP0002136_abnormal_kidney_physiology0.87560075
85MP0009642_abnormal_blood_homeostasis0.87385418
86MP0001819_abnormal_immune_cell0.87367236
87MP0002420_abnormal_adaptive_immunity0.87094172
88MP0001542_abnormal_bone_strength0.86973760
89MP0002006_tumorigenesis0.86596540
90MP0001881_abnormal_mammary_gland0.85167850
91MP0002796_impaired_skin_barrier0.83234743
92MP0005376_homeostasis/metabolism_phenot0.82363661
93MP0010155_abnormal_intestine_physiology0.81998554
94MP0001851_eye_inflammation0.81666592
95MP0002254_reproductive_system_inflammat0.80786938
96MP0009333_abnormal_splenocyte_physiolog0.80716954
97MP0000689_abnormal_spleen_morphology0.78399125
98MP0002998_abnormal_bone_remodeling0.78333751
99MP0003300_gastrointestinal_ulcer0.78196112
100MP0005164_abnormal_response_to0.76558772
101MP0003868_abnormal_feces_composition0.76502547
102MP0005397_hematopoietic_system_phenotyp0.76485467
103MP0001545_abnormal_hematopoietic_system0.76485467
104MP0003763_abnormal_thymus_physiology0.75997756
105MP0004510_myositis0.73661506
106MP0006035_abnormal_mitochondrial_morpho0.72859390
107MP0003011_delayed_dark_adaptation0.72587311
108MP0005023_abnormal_wound_healing0.69614194
109MP0000716_abnormal_immune_system0.69180044
110MP0002722_abnormal_immune_system0.68997161
111MP0002876_abnormal_thyroid_physiology0.68760391
112MP0008873_increased_physiological_sensi0.67781054
113MP0005266_abnormal_metabolism0.66772530
114MP0003303_peritoneal_inflammation0.66704128
115MP0006054_spinal_hemorrhage0.65756016
116MP0002398_abnormal_bone_marrow0.65568910
117MP0005166_decreased_susceptibility_to0.65465927
118MP0002429_abnormal_blood_cell0.65367376
119* MP0000858_altered_metastatic_potential0.63495618
120MP0003075_altered_response_to0.63349996
121MP0010234_abnormal_vibrissa_follicle0.62522421
122MP0002060_abnormal_skin_morphology0.61935756
123MP0001243_abnormal_dermal_layer0.60805759

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)5.05275341
2Abnormality of monocarboxylic acid metabolism (HP:0010996)5.04556377
3Intrahepatic cholestasis (HP:0001406)4.62772545
4Hypobetalipoproteinemia (HP:0003563)4.55316604
5Deep venous thrombosis (HP:0002625)4.52628277
6Xanthomatosis (HP:0000991)4.51621782
7Prolonged partial thromboplastin time (HP:0003645)4.24869139
8Hyperlipoproteinemia (HP:0010980)3.91385181
9Joint hemorrhage (HP:0005261)3.67644833
10Abnormality of glycolipid metabolism (HP:0010969)3.54659319
11Abnormality of liposaccharide metabolism (HP:0010968)3.54659319
12Abnormality of glycosphingolipid metabolism (HP:0004343)3.54659319
13Complement deficiency (HP:0004431)3.49773257
14Abnormality of glutamine family amino acid metabolism (HP:0010902)3.48513528
15Hyperammonemia (HP:0001987)3.47563222
16Recurrent gram-negative bacterial infections (HP:0005420)3.40865462
17Hypolipoproteinemia (HP:0010981)3.37044797
18Abnormality of the common coagulation pathway (HP:0010990)3.36833589
19Hyperbilirubinemia (HP:0002904)3.23401960
20Systemic lupus erythematosus (HP:0002725)3.22255385
21Abnormality of fatty-acid metabolism (HP:0004359)3.19698637
22Prolonged bleeding time (HP:0003010)3.16617014
23Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.16069504
24Increased mean platelet volume (HP:0011877)3.15668455
25Abnormality of sulfur amino acid metabolism (HP:0004339)3.09927920
26Abnormality of pyrimidine metabolism (HP:0004353)3.08617099
27Abnormal platelet volume (HP:0011876)3.08255960
28Conjugated hyperbilirubinemia (HP:0002908)3.06475365
29Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.05090043
30Fat malabsorption (HP:0002630)3.04714461
31Abnormality of methionine metabolism (HP:0010901)2.94406326
32Abnormality of complement system (HP:0005339)2.94384870
33Abnormality of the intrinsic pathway (HP:0010989)2.92044089
34Abnormality of aspartate family amino acid metabolism (HP:0010899)2.90365552
35Hypoalphalipoproteinemia (HP:0003233)2.83723288
36Hyperglycinuria (HP:0003108)2.83471828
37Ketosis (HP:0001946)2.80459490
38Eczematoid dermatitis (HP:0000976)2.78546960
39Myocardial infarction (HP:0001658)2.77874259
40Hyperglycinemia (HP:0002154)2.77266347
41Hypoglycemic coma (HP:0001325)2.71054149
42Epidermoid cyst (HP:0200040)2.70128948
43Hepatosplenomegaly (HP:0001433)2.68636801
44Vacuolated lymphocytes (HP:0001922)2.65625100
45Poikilocytosis (HP:0004447)2.64911226
46Nausea (HP:0002018)2.62454223
47Abnormality of nucleobase metabolism (HP:0010932)2.58454023
48Hypercholesterolemia (HP:0003124)2.57031854
49Abnormality of glycine metabolism (HP:0010895)2.55538449
50Abnormality of serine family amino acid metabolism (HP:0010894)2.55538449
51Acanthocytosis (HP:0001927)2.52378365
52Dysostosis multiplex (HP:0000943)2.51767151
53Steatorrhea (HP:0002570)2.50325297
54Abnormality of iron homeostasis (HP:0011031)2.48273167
55Abnormality of transition element cation homeostasis (HP:0011030)2.47990555
56Metabolic acidosis (HP:0001942)2.47209400
57Dicarboxylic aciduria (HP:0003215)2.46687877
58Abnormality of dicarboxylic acid metabolism (HP:0010995)2.46687877
59Autoimmune thrombocytopenia (HP:0001973)2.44214109
60Increased serum ferritin (HP:0003281)2.42778873
61Vascular calcification (HP:0004934)2.41056956
62Loss of speech (HP:0002371)2.41002247
63Progressive neurologic deterioration (HP:0002344)2.40773951
64Pustule (HP:0200039)2.39726429
65Cholelithiasis (HP:0001081)2.38517067
66Recurrent bacterial skin infections (HP:0005406)2.36885160
67Recurrent abscess formation (HP:0002722)2.36672573
68Abnormal gallbladder morphology (HP:0012437)2.35062677
69Abnormality of purine metabolism (HP:0004352)2.33372486
70Gingival bleeding (HP:0000225)2.29744003
71Lethargy (HP:0001254)2.26598622
72Abnormality of serum amino acid levels (HP:0003112)2.26370851
73Glomerulonephritis (HP:0000099)2.26244334
74Hepatocellular carcinoma (HP:0001402)2.22177953
75Purpura (HP:0000979)2.21728275
76Axonal loss (HP:0003447)2.20502314
77Tetraparesis (HP:0002273)2.17755354
78Cerebral edema (HP:0002181)2.15807330
79Cardiovascular calcification (HP:0011915)2.15557885
80Menorrhagia (HP:0000132)2.12572693
81Generalized aminoaciduria (HP:0002909)2.11814499
82Hypochromic microcytic anemia (HP:0004840)2.10664807
83Amyloidosis (HP:0011034)2.08702229
84Mucopolysacchariduria (HP:0008155)2.08582360
85Urinary glycosaminoglycan excretion (HP:0003541)2.08582360
86Increased cerebral lipofuscin (HP:0011813)2.07374634
87Hydroxyprolinuria (HP:0003080)2.07234433
88Abnormality of proline metabolism (HP:0010907)2.07234433
89Malnutrition (HP:0004395)2.06773273
90Petechiae (HP:0000967)2.06279587
91Vomiting (HP:0002013)2.05867454
92Chronic obstructive pulmonary disease (HP:0006510)2.05579569
93Obstructive lung disease (HP:0006536)2.05579569
94Elevated erythrocyte sedimentation rate (HP:0003565)2.05393612
95Urticaria (HP:0001025)2.05203743
96Vertebral compression fractures (HP:0002953)2.02155599
97Abnormality of polysaccharide metabolism (HP:0011012)2.02130427
98Abnormality of glycosaminoglycan metabolism (HP:0004371)2.02130427
99Abnormality of mucopolysaccharide metabolism (HP:0011020)2.02130427
100Abnormal platelet function (HP:0011869)2.00329439
101Impaired platelet aggregation (HP:0003540)2.00329439
102Hypokinesia (HP:0002375)1.99582468
103Pancreatitis (HP:0001733)1.99544352
104Osteolytic defects of the hand bones (HP:0009699)1.98613575
105Osteolytic defects of the phalanges of the hand (HP:0009771)1.98613575
106Abnormality of macrophages (HP:0004311)1.97053396
107Decreased activity of mitochondrial respiratory chain (HP:0008972)1.97006422
108Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.97006422
109Abnormality of the heme biosynthetic pathway (HP:0010472)1.96541886
110Micronodular cirrhosis (HP:0001413)1.95367638
111Opisthotonus (HP:0002179)1.95143425
112Sensorimotor neuropathy (HP:0007141)1.92729254
113Reticulocytosis (HP:0001923)1.91762591
114Microcytic anemia (HP:0001935)1.91416382
115Hypertriglyceridemia (HP:0002155)1.91346258
116Abnormality of the vasculature of the conjunctiva (HP:0008054)1.90382801
117Alkalosis (HP:0001948)1.89082652
118Skin nodule (HP:0200036)1.88999471
119Increased IgM level (HP:0003496)1.88648754
120Bone pain (HP:0002653)1.88386672
121Rough bone trabeculation (HP:0100670)1.87421154
122Abnormality of the gallbladder (HP:0005264)1.87357807
123Epistaxis (HP:0000421)1.86912419
124Ketoacidosis (HP:0001993)1.86541621
125Joint swelling (HP:0001386)1.86050196
126Brushfield spots (HP:0001088)1.85287171
127Prolonged neonatal jaundice (HP:0006579)1.85171860
128Spontaneous abortion (HP:0005268)1.83919968
129Abnormal cartilage morphology (HP:0002763)1.83760182
130Paralysis (HP:0003470)1.83374144
131Irritability (HP:0000737)1.82939033
132Abnormal gallbladder physiology (HP:0012438)1.82874178
133Orchitis (HP:0100796)1.79880468
134Orthostatic hypotension (HP:0001278)1.78222334
135Rickets (HP:0002748)1.76968369
136Autoimmune hemolytic anemia (HP:0001890)1.75509467
137Anorexia (HP:0002039)1.74892781
138Abnormality of the Achilles tendon (HP:0005109)1.73911520
139Abnormal trabecular bone morphology (HP:0100671)1.73400234
140Cardiomegaly (HP:0001640)1.72738542
141Conjunctival telangiectasia (HP:0000524)1.72701892
142Symptomatic seizures (HP:0011145)1.72467467
143Increased neuronal autofluorescent lipopigment (HP:0002074)1.72301782
144Right ventricular cardiomyopathy (HP:0011663)1.71635985
145Stomatitis (HP:0010280)1.67895825
146Myositis (HP:0100614)1.67810129
147Abnormal pupillary function (HP:0007686)1.66150893
148Reduced antithrombin III activity (HP:0001976)1.65076644

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN13.34782401
2BCKDK3.27122732
3PIM23.16167344
4NME22.86596046
5BLK2.60430984
6TBK12.52166533
7MAP3K142.34682278
8TYK22.29753888
9MAP4K12.29043796
10EIF2AK12.28895372
11NEK92.25159443
12FGFR42.12471858
13MAP3K112.10667717
14IRAK32.01396668
15ZAP701.96184699
16ARAF1.88282321
17MAP3K31.79052980
18MST1R1.78327825
19TAOK31.76880744
20TESK11.74697153
21IKBKE1.70383359
22TRIB31.68897641
23MAP2K31.67123456
24KDR1.53038025
25BMX1.48591724
26ABL21.40120388
27BMPR21.39484860
28IRAK41.36584050
29PIM11.32528244
30FRK1.32359544
31KIT1.29704813
32IKBKB1.28671894
33SCYL21.28549803
34RIPK41.28497943
35JAK11.28208764
36PKN21.27533768
37MAPKAPK31.27496129
38JAK31.21601392
39STK241.19568783
40PBK1.19563297
41TXK1.18022294
42SYK1.17364515
43MET1.16028213
44FLT31.14135593
45TEC1.02265937
46GRK61.01948181
47ILK1.00849192
48MAP3K121.00434666
49RPS6KA40.99118079
50LMTK20.97612118
51MST40.94714418
52JAK20.94371730
53MAP3K50.92887198
54MYLK0.89182667
55TESK20.88351606
56LRRK20.87104772
57DAPK10.86829767
58EIF2AK30.86498079
59CDK60.85005526
60PRPF4B0.84958019
61NEK10.82944330
62RPS6KB20.82819416
63SIK10.82257242
64PIK3CG0.81811981
65BRAF0.81214123
66PDK30.80788182
67PDK40.80788182
68MAPK110.78916071
69STK100.75685095
70STK160.75574026
71SIK30.74566196
72VRK20.73636911
73STK40.73114237
74FER0.73025080
75ZAK0.72288993
76BTK0.69541534
77MATK0.68169458
78SMG10.67214204
79EPHA30.66764577
80PRKG20.65295443
81ACVR1B0.65019148
82IRAK10.64813140
83YES10.64497691
84IRAK20.64297688
85FGR0.63852562
86TAOK20.63828603
87CHUK0.63619439
88ERBB40.63450179
89PAK10.60533909
90LYN0.60100134
91PRKCI0.59829164
92CSK0.59323589
93MARK30.57995406
94MAP3K10.56480596
95MAP2K10.55713416
96TRPM70.55290460
97NME10.53564338
98ALK0.53050908
99MAP3K80.51997235
100PDK20.50924137
101LCK0.50892465
102PDPK10.50123200
103BUB10.49701042
104EPHB10.49463324
105LIMK10.48086461
106DYRK1B0.46736025
107TAOK10.46671536
108PRKCD0.46208169
109PTK20.46128137
110MAP2K20.44942122
111CSF1R0.44891096
112RIPK10.44092178
113EPHA20.43142848
114MAP2K60.42243766
115DAPK30.40797410
116MAP3K20.40209245
117RAF10.39955430
118PTK60.38427098
119TGFBR20.37522165
120TTK0.37405017
121FGFR30.36047003
122MAP3K130.35938208
123MAPKAPK20.35497394
124HCK0.35364586
125PAK40.35319979
126BRSK20.35295826
127CAMK2G0.34688770
128KSR20.31511101

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.63874505
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.93213319
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.81419278
4Caffeine metabolism_Homo sapiens_hsa002322.59495052
5Pentose and glucuronate interconversions_Homo sapiens_hsa000402.46580302
6Complement and coagulation cascades_Homo sapiens_hsa046102.42147931
7Fatty acid degradation_Homo sapiens_hsa000712.34558720
8Tryptophan metabolism_Homo sapiens_hsa003802.32301274
9Arginine biosynthesis_Homo sapiens_hsa002202.31395929
10Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.16977226
11Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.16553869
12Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.16519024
13Chemical carcinogenesis_Homo sapiens_hsa052042.09810285
14Staphylococcus aureus infection_Homo sapiens_hsa051502.06478831
15Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.02974716
16Peroxisome_Homo sapiens_hsa041462.02292312
17Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.00118149
18Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.84261282
19Nitrogen metabolism_Homo sapiens_hsa009101.82156678
20Drug metabolism - other enzymes_Homo sapiens_hsa009831.78192699
21Histidine metabolism_Homo sapiens_hsa003401.73771294
22Folate biosynthesis_Homo sapiens_hsa007901.68858071
23Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.66866840
24PPAR signaling pathway_Homo sapiens_hsa033201.64755060
25Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.58338740
26beta-Alanine metabolism_Homo sapiens_hsa004101.57531582
27Steroid hormone biosynthesis_Homo sapiens_hsa001401.57525263
28Retinol metabolism_Homo sapiens_hsa008301.57064278
29Propanoate metabolism_Homo sapiens_hsa006401.56534775
30Selenocompound metabolism_Homo sapiens_hsa004501.51181445
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.51178524
32Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.43137336
33Fatty acid metabolism_Homo sapiens_hsa012121.38958753
34Phenylalanine metabolism_Homo sapiens_hsa003601.35382509
35Sulfur relay system_Homo sapiens_hsa041221.33522342
36Proteasome_Homo sapiens_hsa030501.32735233
37Pyruvate metabolism_Homo sapiens_hsa006201.32645804
382-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.31113519
39Sulfur metabolism_Homo sapiens_hsa009201.26765991
40Starch and sucrose metabolism_Homo sapiens_hsa005001.26086316
41Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.24644012
42Carbon metabolism_Homo sapiens_hsa012001.24585415
43Glutathione metabolism_Homo sapiens_hsa004801.23529016
44ABC transporters_Homo sapiens_hsa020101.20116333
45Pentose phosphate pathway_Homo sapiens_hsa000301.19134771
46Tyrosine metabolism_Homo sapiens_hsa003501.17861776
47Butanoate metabolism_Homo sapiens_hsa006501.15158029
48Cyanoamino acid metabolism_Homo sapiens_hsa004601.14072917
49Cysteine and methionine metabolism_Homo sapiens_hsa002701.13645233
50Vitamin B6 metabolism_Homo sapiens_hsa007501.08583746
51Steroid biosynthesis_Homo sapiens_hsa001001.07081389
52Fat digestion and absorption_Homo sapiens_hsa049751.07024503
53SNARE interactions in vesicular transport_Homo sapiens_hsa041301.03063202
54Shigellosis_Homo sapiens_hsa051311.01740275
55Bile secretion_Homo sapiens_hsa049760.97647219
56Biosynthesis of amino acids_Homo sapiens_hsa012300.96654859
57Fatty acid elongation_Homo sapiens_hsa000620.91425518
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.91242122
59Mineral absorption_Homo sapiens_hsa049780.90872247
60Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.90849562
61Sphingolipid metabolism_Homo sapiens_hsa006000.90761276
62Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.89762984
63Renin-angiotensin system_Homo sapiens_hsa046140.88676347
64Vitamin digestion and absorption_Homo sapiens_hsa049770.85739497
65One carbon pool by folate_Homo sapiens_hsa006700.84798245
66Rheumatoid arthritis_Homo sapiens_hsa053230.84179615
67Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.83356570
68Osteoclast differentiation_Homo sapiens_hsa043800.81590407
69Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.81361150
70Collecting duct acid secretion_Homo sapiens_hsa049660.75335051
71Vibrio cholerae infection_Homo sapiens_hsa051100.74626848
72Salmonella infection_Homo sapiens_hsa051320.72734811
73Autoimmune thyroid disease_Homo sapiens_hsa053200.72330217
74Hepatitis C_Homo sapiens_hsa051600.71924444
75Glycerolipid metabolism_Homo sapiens_hsa005610.70736702
76Type I diabetes mellitus_Homo sapiens_hsa049400.69903491
77Platelet activation_Homo sapiens_hsa046110.68684556
78Arginine and proline metabolism_Homo sapiens_hsa003300.66698951
79Lysosome_Homo sapiens_hsa041420.64709338
80Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.63415322
81Fructose and mannose metabolism_Homo sapiens_hsa000510.63091189
82Mismatch repair_Homo sapiens_hsa034300.62669009
83Legionellosis_Homo sapiens_hsa051340.62509932
84Galactose metabolism_Homo sapiens_hsa000520.61777576
85Leukocyte transendothelial migration_Homo sapiens_hsa046700.60636955
86Influenza A_Homo sapiens_hsa051640.58648193
87Other glycan degradation_Homo sapiens_hsa005110.57514711
88Metabolic pathways_Homo sapiens_hsa011000.56971774
89Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.56579220
90Asthma_Homo sapiens_hsa053100.56165623
91Leishmaniasis_Homo sapiens_hsa051400.54353888
92Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.52858054
93Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.52349462
94Herpes simplex infection_Homo sapiens_hsa051680.52326424
95Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.52168553
96Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.51652328
97N-Glycan biosynthesis_Homo sapiens_hsa005100.50362148
98Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.50341510
99NOD-like receptor signaling pathway_Homo sapiens_hsa046210.48056296
100Intestinal immune network for IgA production_Homo sapiens_hsa046720.47457189
101Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.47441766
102Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.47140083
103Toxoplasmosis_Homo sapiens_hsa051450.45325217
104Protein export_Homo sapiens_hsa030600.41051390
105RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.39097952
106Glycosaminoglycan degradation_Homo sapiens_hsa005310.38231792
107Regulation of autophagy_Homo sapiens_hsa041400.37733511
108Pertussis_Homo sapiens_hsa051330.37493007
109Maturity onset diabetes of the young_Homo sapiens_hsa049500.35725929
110Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.35634239
111Adipocytokine signaling pathway_Homo sapiens_hsa049200.33541225
112Linoleic acid metabolism_Homo sapiens_hsa005910.33132311
113Pyrimidine metabolism_Homo sapiens_hsa002400.33057380
114Hematopoietic cell lineage_Homo sapiens_hsa046400.32830902
115Antigen processing and presentation_Homo sapiens_hsa046120.30953070
116Graft-versus-host disease_Homo sapiens_hsa053320.29747273
117Arachidonic acid metabolism_Homo sapiens_hsa005900.29738034
118Malaria_Homo sapiens_hsa051440.29589952
119Apoptosis_Homo sapiens_hsa042100.29120820
120NF-kappa B signaling pathway_Homo sapiens_hsa040640.29117525
121Toll-like receptor signaling pathway_Homo sapiens_hsa046200.28536892
122Phagosome_Homo sapiens_hsa041450.27624099
123Measles_Homo sapiens_hsa051620.24024009
124Tuberculosis_Homo sapiens_hsa051520.23918852
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.23000281
126Oxidative phosphorylation_Homo sapiens_hsa001900.22893568
127Ribosome_Homo sapiens_hsa030100.22880391
128Allograft rejection_Homo sapiens_hsa053300.21633281

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