

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | neutrophil activation involved in immune response (GO:0002283) | 6.41504117 |
| 2 | positive regulation of mast cell activation (GO:0033005) | 4.40767984 |
| 3 | response to peptidoglycan (GO:0032494) | 4.36186542 |
| 4 | granulocyte activation (GO:0036230) | 4.07285476 |
| 5 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.05162692 |
| 6 | neutrophil activation (GO:0042119) | 4.03014467 |
| 7 | regulation of platelet aggregation (GO:0090330) | 3.97358971 |
| 8 | cellular extravasation (GO:0045123) | 3.96424039 |
| 9 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.92225769 |
| 10 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.87010604 |
| 11 | regulation of mast cell degranulation (GO:0043304) | 3.83817810 |
| 12 | regulation of platelet activation (GO:0010543) | 3.76874312 |
| 13 | adenosine receptor signaling pathway (GO:0001973) | 3.73469753 |
| 14 | cellular response to thyroid hormone stimulus (GO:0097067) | 3.73074558 |
| 15 | positive regulation of macrophage differentiation (GO:0045651) | 3.63855212 |
| 16 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.61957129 |
| 17 | detection of molecule of bacterial origin (GO:0032490) | 3.56408327 |
| 18 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.55124721 |
| 19 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.54326625 |
| 20 | thrombin receptor signaling pathway (GO:0070493) | 3.49708672 |
| 21 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.48389083 |
| 22 | positive regulation of mast cell degranulation (GO:0043306) | 3.48389083 |
| 23 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.47332261 |
| 24 | regulation of mast cell activation (GO:0033003) | 3.41352108 |
| 25 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 3.39890871 |
| 26 | negative regulation of interleukin-12 production (GO:0032695) | 3.38385516 |
| 27 | protein neddylation (GO:0045116) | 3.37835924 |
| 28 | platelet aggregation (GO:0070527) | 3.33555924 |
| 29 | regulation of neuron projection regeneration (GO:0070570) | 3.33285740 |
| 30 | regulation of axon regeneration (GO:0048679) | 3.33285740 |
| 31 | germinal center formation (GO:0002467) | 3.26514458 |
| 32 | regulation of leukocyte degranulation (GO:0043300) | 3.20055143 |
| 33 | positive regulation of leukocyte degranulation (GO:0043302) | 3.18355004 |
| 34 | glycosphingolipid catabolic process (GO:0046479) | 3.15276148 |
| 35 | leukocyte degranulation (GO:0043299) | 3.14251112 |
| 36 | regulation of integrin activation (GO:0033623) | 3.13744187 |
| 37 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.12882740 |
| 38 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.12882740 |
| 39 | modulation by symbiont of host immune response (GO:0052553) | 3.12882740 |
| 40 | positive regulation by symbiont of host defense response (GO:0052509) | 3.12882740 |
| 41 | modulation by symbiont of host defense response (GO:0052031) | 3.12882740 |
| 42 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.12882740 |
| 43 | response to thyroid hormone (GO:0097066) | 3.11519851 |
| 44 | myeloid cell activation involved in immune response (GO:0002275) | 3.10736960 |
| 45 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 3.07920609 |
| 46 | positive regulation of receptor recycling (GO:0001921) | 3.04081490 |
| 47 | oligosaccharide catabolic process (GO:0009313) | 3.00806569 |
| 48 | negative regulation of protein localization to plasma membrane (GO:1903077) | 3.00791756 |
| 49 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.00330311 |
| 50 | regulation of integrin-mediated signaling pathway (GO:2001044) | 3.00138053 |
| 51 | macrophage activation involved in immune response (GO:0002281) | 2.97800930 |
| 52 | regulation of vitamin D biosynthetic process (GO:0060556) | 2.97474498 |
| 53 | negative regulation of interleukin-17 production (GO:0032700) | 2.97180287 |
| 54 | regulation of transmission of nerve impulse (GO:0051969) | 2.95974831 |
| 55 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.95582150 |
| 56 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 2.92390368 |
| 57 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.88833147 |
| 58 | protein localization to endosome (GO:0036010) | 2.86991807 |
| 59 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.84786081 |
| 60 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.81068608 |
| 61 | lipoxygenase pathway (GO:0019372) | 2.80245367 |
| 62 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.79637329 |
| 63 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.78429880 |
| 64 | negative regulation of platelet activation (GO:0010544) | 2.76503695 |
| 65 | glycolipid catabolic process (GO:0019377) | 2.75440325 |
| 66 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.74609031 |
| 67 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.73493180 |
| 68 | hepatocyte apoptotic process (GO:0097284) | 2.73009891 |
| 69 | platelet degranulation (GO:0002576) | 2.72507185 |
| 70 | megakaryocyte development (GO:0035855) | 2.70604002 |
| 71 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.70285340 |
| 72 | regulation of homotypic cell-cell adhesion (GO:0034110) | 2.68689100 |
| 73 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.67369603 |
| 74 | hypotonic response (GO:0006971) | 2.66533094 |
| 75 | detection of other organism (GO:0098543) | 2.66200064 |
| 76 | regulation of early endosome to late endosome transport (GO:2000641) | 2.64287109 |
| 77 | detection of external biotic stimulus (GO:0098581) | 2.63878559 |
| 78 | positive regulation of interleukin-6 production (GO:0032755) | 2.63678149 |
| 79 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.63160561 |
| 80 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 2.62682594 |
| 81 | platelet formation (GO:0030220) | 2.60626493 |
| 82 | cellular response to arsenic-containing substance (GO:0071243) | 2.59628457 |
| 83 | leukocyte aggregation (GO:0070486) | 2.58757003 |
| 84 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.55476575 |
| 85 | iron ion import (GO:0097286) | 2.53681356 |
| 86 | positive regulation of B cell differentiation (GO:0045579) | 2.53448084 |
| 87 | regulation of interleukin-17 production (GO:0032660) | 2.53433449 |
| 88 | G-protein coupled purinergic receptor signaling pathway (GO:0035588) | 2.52305118 |
| 89 | negative regulation of stress fiber assembly (GO:0051497) | 2.52071256 |
| 90 | homotypic cell-cell adhesion (GO:0034109) | 2.50911194 |
| 91 | mesodermal cell differentiation (GO:0048333) | 2.50236639 |
| 92 | positive regulation of hemostasis (GO:1900048) | 2.49109110 |
| 93 | positive regulation of blood coagulation (GO:0030194) | 2.49109110 |
| 94 | negative regulation of lipid storage (GO:0010888) | 2.47727920 |
| 95 | immunoglobulin mediated immune response (GO:0016064) | 2.46084871 |
| 96 | cellular response to molecule of bacterial origin (GO:0071219) | 2.42512773 |
| 97 | positive regulation of tumor necrosis factor production (GO:0032760) | 2.40665191 |
| 98 | phagocytosis, engulfment (GO:0006911) | 2.40579919 |
| 99 | cellular response to lipopolysaccharide (GO:0071222) | 2.40540566 |
| 100 | platelet activation (GO:0030168) | 2.39325350 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.56848421 |
| 2 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 3.41864512 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.38414958 |
| 4 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.20664920 |
| 5 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.18028964 |
| 6 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 3.06072953 |
| 7 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.00942520 |
| 8 | SPI1_23127762_ChIP-Seq_K562_Human | 2.78661473 |
| 9 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.70094245 |
| 10 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.69285563 |
| 11 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.67490931 |
| 12 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.60914950 |
| 13 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.57579918 |
| 14 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.53509977 |
| 15 | GATA1_19941826_ChIP-Seq_K562_Human | 2.48270281 |
| 16 | GATA1_22025678_ChIP-Seq_K562_Human | 2.47002959 |
| 17 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.36336612 |
| 18 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.32264195 |
| 19 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.29213664 |
| 20 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.21805438 |
| 21 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 2.19080146 |
| 22 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.12560001 |
| 23 | GATA2_19941826_ChIP-Seq_K562_Human | 2.11956427 |
| 24 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.10305775 |
| 25 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.06915282 |
| 26 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.05922503 |
| 27 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.05127228 |
| 28 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.03866599 |
| 29 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.99776594 |
| 30 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.99656385 |
| 31 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.96566926 |
| 32 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.94004841 |
| 33 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.89743264 |
| 34 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.86227267 |
| 35 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.86108304 |
| 36 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.83805235 |
| 37 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.82202389 |
| 38 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.80828029 |
| 39 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.79296482 |
| 40 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.77325144 |
| 41 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.72157795 |
| 42 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.69869063 |
| 43 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.65653903 |
| 44 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.65422829 |
| 45 | MYC_22102868_ChIP-Seq_BL_Human | 1.62573079 |
| 46 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.61681446 |
| 47 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.57800290 |
| 48 | MAF_26560356_Chip-Seq_TH1_Human | 1.55133095 |
| 49 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.54830064 |
| 50 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.54445429 |
| 51 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.49221139 |
| 52 | MYB_26560356_Chip-Seq_TH2_Human | 1.47963215 |
| 53 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.47521693 |
| 54 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.45237340 |
| 55 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.44267186 |
| 56 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.42497901 |
| 57 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.39842679 |
| 58 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.37630584 |
| 59 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.37451686 |
| 60 | UTX_26944678_Chip-Seq_JUKART_Human | 1.36059868 |
| 61 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.35533108 |
| 62 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.34707533 |
| 63 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34008537 |
| 64 | MYB_26560356_Chip-Seq_TH1_Human | 1.33777587 |
| 65 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.33130932 |
| 66 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.32674346 |
| 67 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.29356615 |
| 68 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.28766899 |
| 69 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.25490988 |
| 70 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24860681 |
| 71 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.21915719 |
| 72 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.21667569 |
| 73 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.17820390 |
| 74 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.14998978 |
| 75 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.14219191 |
| 76 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.13951977 |
| 77 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.13866724 |
| 78 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.13162300 |
| 79 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.13109943 |
| 80 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.12424082 |
| 81 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.11593767 |
| 82 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.10011890 |
| 83 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.07689079 |
| 84 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.07689079 |
| 85 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.07100682 |
| 86 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.06896055 |
| 87 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.05661854 |
| 88 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.05408732 |
| 89 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.04466428 |
| 90 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.04112015 |
| 91 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.02221793 |
| 92 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.02150006 |
| 93 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.99247732 |
| 94 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.98706308 |
| 95 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.98050481 |
| 96 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.97731493 |
| 97 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.96421985 |
| 98 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.94483783 |
| 99 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.93394551 |
| 100 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.92529058 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005464_abnormal_platelet_physiology | 4.82319035 |
| 2 | MP0002877_abnormal_melanocyte_morpholog | 3.54659557 |
| 3 | MP0003724_increased_susceptibility_to | 3.51129128 |
| 4 | MP0003303_peritoneal_inflammation | 3.44614251 |
| 5 | MP0003436_decreased_susceptibility_to | 2.86556708 |
| 6 | MP0000343_altered_response_to | 2.70684448 |
| 7 | MP0005058_abnormal_lysosome_morphology | 2.66731562 |
| 8 | MP0005451_abnormal_body_composition | 2.61703225 |
| 9 | MP0001835_abnormal_antigen_presentation | 2.59651946 |
| 10 | MP0003191_abnormal_cellular_cholesterol | 2.52759958 |
| 11 | MP0002148_abnormal_hypersensitivity_rea | 2.48451549 |
| 12 | MP0008004_abnormal_stomach_pH | 2.27485039 |
| 13 | MP0002419_abnormal_innate_immunity | 2.23399741 |
| 14 | MP0004510_myositis | 2.18184536 |
| 15 | MP0003656_abnormal_erythrocyte_physiolo | 2.05831693 |
| 16 | MP0005000_abnormal_immune_tolerance | 2.04478946 |
| 17 | MP0003300_gastrointestinal_ulcer | 1.97897153 |
| 18 | MP0000858_altered_metastatic_potential | 1.97584738 |
| 19 | MP0009840_abnormal_foam_cell | 1.92084561 |
| 20 | MP0009278_abnormal_bone_marrow | 1.90856515 |
| 21 | MP0005397_hematopoietic_system_phenotyp | 1.81762011 |
| 22 | MP0001545_abnormal_hematopoietic_system | 1.81762011 |
| 23 | MP0003566_abnormal_cell_adhesion | 1.81418682 |
| 24 | MP0003828_pulmonary_edema | 1.80948707 |
| 25 | MP0002452_abnormal_antigen_presenting | 1.70894220 |
| 26 | MP0005025_abnormal_response_to | 1.70682630 |
| 27 | MP0001533_abnormal_skeleton_physiology | 1.70275490 |
| 28 | MP0004947_skin_inflammation | 1.69790179 |
| 29 | MP0009785_altered_susceptibility_to | 1.67726740 |
| 30 | MP0009764_decreased_sensitivity_to | 1.66252977 |
| 31 | MP0002723_abnormal_immune_serum | 1.65019442 |
| 32 | MP0003172_abnormal_lysosome_physiology | 1.62041647 |
| 33 | MP0002332_abnormal_exercise_endurance | 1.50515717 |
| 34 | MP0005171_absent_coat_pigmentation | 1.50167261 |
| 35 | MP0005387_immune_system_phenotype | 1.50086737 |
| 36 | MP0001790_abnormal_immune_system | 1.50086737 |
| 37 | MP0003950_abnormal_plasma_membrane | 1.49213407 |
| 38 | MP0003075_altered_response_to | 1.48166449 |
| 39 | MP0002420_abnormal_adaptive_immunity | 1.43423275 |
| 40 | MP0001819_abnormal_immune_cell | 1.42275940 |
| 41 | MP0005671_abnormal_response_to | 1.41616093 |
| 42 | MP0001800_abnormal_humoral_immune | 1.39274916 |
| 43 | MP0002998_abnormal_bone_remodeling | 1.37162093 |
| 44 | MP0001845_abnormal_inflammatory_respons | 1.36426505 |
| 45 | MP0003448_altered_tumor_morphology | 1.34073992 |
| 46 | MP0002398_abnormal_bone_marrow | 1.32946498 |
| 47 | MP0009333_abnormal_splenocyte_physiolog | 1.32556814 |
| 48 | MP0000685_abnormal_immune_system | 1.32330861 |
| 49 | MP0000015_abnormal_ear_pigmentation | 1.30664959 |
| 50 | MP0005164_abnormal_response_to | 1.28368049 |
| 51 | MP0005167_abnormal_blood-brain_barrier | 1.28073524 |
| 52 | MP0006082_CNS_inflammation | 1.24356860 |
| 53 | MP0003705_abnormal_hypodermis_morpholog | 1.23102795 |
| 54 | MP0008260_abnormal_autophagy | 1.23042470 |
| 55 | MP0010155_abnormal_intestine_physiology | 1.22846530 |
| 56 | MP0000465_gastrointestinal_hemorrhage | 1.18176049 |
| 57 | MP0009763_increased_sensitivity_to | 1.17855133 |
| 58 | MP0002405_respiratory_system_inflammati | 1.13855684 |
| 59 | MP0000716_abnormal_immune_system | 1.09714770 |
| 60 | MP0002429_abnormal_blood_cell | 1.08692626 |
| 61 | MP0004782_abnormal_surfactant_physiolog | 1.08547707 |
| 62 | MP0010352_gastrointestinal_tract_polyps | 1.08013619 |
| 63 | MP0005408_hypopigmentation | 1.06914421 |
| 64 | MP0004808_abnormal_hematopoietic_stem | 1.06166040 |
| 65 | MP0002132_abnormal_respiratory_system | 1.06080374 |
| 66 | MP0003091_abnormal_cell_migration | 1.05765547 |
| 67 | MP0000249_abnormal_blood_vessel | 1.05160717 |
| 68 | MP0000689_abnormal_spleen_morphology | 1.04228994 |
| 69 | MP0008469_abnormal_protein_level | 1.03795396 |
| 70 | MP0002722_abnormal_immune_system | 1.03588208 |
| 71 | MP0003453_abnormal_keratinocyte_physiol | 1.02883391 |
| 72 | MP0003806_abnormal_nucleotide_metabolis | 1.02477771 |
| 73 | MP0004130_abnormal_muscle_cell | 1.00077541 |
| 74 | MP0005166_decreased_susceptibility_to | 0.96400198 |
| 75 | MP0001853_heart_inflammation | 0.95893727 |
| 76 | MP0002006_tumorigenesis | 0.94079268 |
| 77 | MP0005023_abnormal_wound_healing | 0.88317944 |
| 78 | MP0004036_abnormal_muscle_relaxation | 0.85189547 |
| 79 | MP0000569_abnormal_digit_pigmentation | 0.84045155 |
| 80 | MP0005165_increased_susceptibility_to | 0.82784719 |
| 81 | MP0000749_muscle_degeneration | 0.82003752 |
| 82 | MP0006054_spinal_hemorrhage | 0.81226579 |
| 83 | MP0005174_abnormal_tail_pigmentation | 0.80992030 |
| 84 | MP0004883_abnormal_blood_vessel | 0.79916997 |
| 85 | MP0004381_abnormal_hair_follicle | 0.78652055 |
| 86 | MP0004084_abnormal_cardiac_muscle | 0.77668502 |
| 87 | MP0005666_abnormal_adipose_tissue | 0.77392846 |
| 88 | MP0003795_abnormal_bone_structure | 0.75895619 |
| 89 | MP0002166_altered_tumor_susceptibility | 0.75315978 |
| 90 | MP0000604_amyloidosis | 0.74872417 |
| 91 | MP0001851_eye_inflammation | 0.74546382 |
| 92 | MP0005083_abnormal_biliary_tract | 0.73838581 |
| 93 | MP0003045_fibrosis | 0.70204787 |
| 94 | MP0005621_abnormal_cell_physiology | 0.70126709 |
| 95 | MP0008438_abnormal_cutaneous_collagen | 0.68816704 |
| 96 | MP0000358_abnormal_cell_content/ | 0.68776717 |
| 97 | MP0003221_abnormal_cardiomyocyte_apopto | 0.68489059 |
| 98 | MP0009765_abnormal_xenobiotic_induced | 0.68284376 |
| 99 | MP0003763_abnormal_thymus_physiology | 0.67809775 |
| 100 | MP0000371_diluted_coat_color | 0.67429675 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Prolonged bleeding time (HP:0003010) | 5.89120602 |
| 2 | Increased mean platelet volume (HP:0011877) | 5.55779045 |
| 3 | Abnormal platelet volume (HP:0011876) | 5.40076662 |
| 4 | Petechiae (HP:0000967) | 5.16792931 |
| 5 | Menorrhagia (HP:0000132) | 5.13030969 |
| 6 | Purpura (HP:0000979) | 4.52583781 |
| 7 | Epistaxis (HP:0000421) | 4.48079818 |
| 8 | Abnormality of macrophages (HP:0004311) | 4.46376084 |
| 9 | Myocardial infarction (HP:0001658) | 3.90766768 |
| 10 | Abnormal platelet function (HP:0011869) | 3.85610498 |
| 11 | Impaired platelet aggregation (HP:0003540) | 3.85610498 |
| 12 | Gingival bleeding (HP:0000225) | 3.70956789 |
| 13 | Eczematoid dermatitis (HP:0000976) | 3.52491280 |
| 14 | Recurrent bacterial skin infections (HP:0005406) | 3.36117013 |
| 15 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.33509548 |
| 16 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.33509548 |
| 17 | Abnormality of glycolipid metabolism (HP:0010969) | 3.33509548 |
| 18 | Recurrent abscess formation (HP:0002722) | 3.33067221 |
| 19 | Spontaneous hematomas (HP:0007420) | 3.10518450 |
| 20 | Vacuolated lymphocytes (HP:0001922) | 2.95566157 |
| 21 | Hepatosplenomegaly (HP:0001433) | 2.88746845 |
| 22 | Polycythemia (HP:0001901) | 2.87149386 |
| 23 | Upper limb muscle weakness (HP:0003484) | 2.86626973 |
| 24 | Dysostosis multiplex (HP:0000943) | 2.74272917 |
| 25 | Abnormality of the common coagulation pathway (HP:0010990) | 2.71073512 |
| 26 | Distal lower limb amyotrophy (HP:0008944) | 2.65018640 |
| 27 | Obstructive lung disease (HP:0006536) | 2.61769405 |
| 28 | Chronic obstructive pulmonary disease (HP:0006510) | 2.61769405 |
| 29 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.59583707 |
| 30 | Stomatitis (HP:0010280) | 2.58580068 |
| 31 | Fatigue (HP:0012378) | 2.56471556 |
| 32 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.45899243 |
| 33 | Increased serum ferritin (HP:0003281) | 2.44944648 |
| 34 | Conjunctival telangiectasia (HP:0000524) | 2.44424201 |
| 35 | Orchitis (HP:0100796) | 2.44387515 |
| 36 | Abnormal gallbladder physiology (HP:0012438) | 2.43598295 |
| 37 | Cholecystitis (HP:0001082) | 2.43598295 |
| 38 | Arterial thrombosis (HP:0004420) | 2.43267574 |
| 39 | Increased cerebral lipofuscin (HP:0011813) | 2.37848234 |
| 40 | Retrobulbar optic neuritis (HP:0100654) | 2.37356502 |
| 41 | Optic neuritis (HP:0100653) | 2.37356502 |
| 42 | Episodic fever (HP:0001954) | 2.36018476 |
| 43 | Paralysis (HP:0003470) | 2.34614857 |
| 44 | Abnormality of the sella turcica (HP:0002679) | 2.34037007 |
| 45 | Loss of speech (HP:0002371) | 2.23460792 |
| 46 | Abnormality of iron homeostasis (HP:0011031) | 2.21496077 |
| 47 | Hyperlipoproteinemia (HP:0010980) | 2.19317015 |
| 48 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.18389069 |
| 49 | Osteolytic defects of the hand bones (HP:0009699) | 2.18389069 |
| 50 | Increased connective tissue (HP:0009025) | 2.17110183 |
| 51 | Bruising susceptibility (HP:0000978) | 2.17022272 |
| 52 | Myositis (HP:0100614) | 2.12987933 |
| 53 | Nausea (HP:0002018) | 2.03969930 |
| 54 | Hypertensive crisis (HP:0100735) | 2.03252624 |
| 55 | Male infertility (HP:0003251) | 2.03180991 |
| 56 | Recurrent skin infections (HP:0001581) | 2.02227486 |
| 57 | Thick nail (HP:0001805) | 1.98206132 |
| 58 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.97771702 |
| 59 | Poikilocytosis (HP:0004447) | 1.96478999 |
| 60 | Orthostatic hypotension (HP:0001278) | 1.95359294 |
| 61 | Amyloidosis (HP:0011034) | 1.94479978 |
| 62 | Distal lower limb muscle weakness (HP:0009053) | 1.93807870 |
| 63 | Nemaline bodies (HP:0003798) | 1.92837479 |
| 64 | Tinnitus (HP:0000360) | 1.91549721 |
| 65 | Mucosal telangiectasiae (HP:0100579) | 1.90919497 |
| 66 | Albinism (HP:0001022) | 1.90114587 |
| 67 | Ventricular fibrillation (HP:0001663) | 1.88431308 |
| 68 | Recurrent fungal infections (HP:0002841) | 1.87155949 |
| 69 | Encephalitis (HP:0002383) | 1.87024384 |
| 70 | Lower limb amyotrophy (HP:0007210) | 1.86478124 |
| 71 | Keratoconjunctivitis sicca (HP:0001097) | 1.85608042 |
| 72 | Anorexia (HP:0002039) | 1.82903717 |
| 73 | Thrombocytosis (HP:0001894) | 1.82766231 |
| 74 | Urticaria (HP:0001025) | 1.80893231 |
| 75 | Chest pain (HP:0100749) | 1.80799735 |
| 76 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.79916710 |
| 77 | Recurrent viral infections (HP:0004429) | 1.79466083 |
| 78 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.78383215 |
| 79 | Subacute progressive viral hepatitis (HP:0006572) | 1.77606789 |
| 80 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.76909057 |
| 81 | Abnormality of the Achilles tendon (HP:0005109) | 1.76260783 |
| 82 | Autoimmune hemolytic anemia (HP:0001890) | 1.75244652 |
| 83 | Acanthocytosis (HP:0001927) | 1.73905272 |
| 84 | Muscle fiber inclusion bodies (HP:0100299) | 1.73731888 |
| 85 | Hypertriglyceridemia (HP:0002155) | 1.73635874 |
| 86 | Amaurosis fugax (HP:0100576) | 1.71065050 |
| 87 | Mediastinal lymphadenopathy (HP:0100721) | 1.70906236 |
| 88 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.70595034 |
| 89 | Tetraparesis (HP:0002273) | 1.70446854 |
| 90 | Abnormal pupillary function (HP:0007686) | 1.69403610 |
| 91 | Joint swelling (HP:0001386) | 1.69091996 |
| 92 | Mitral stenosis (HP:0001718) | 1.69029292 |
| 93 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.68955928 |
| 94 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.68691796 |
| 95 | Xanthomatosis (HP:0000991) | 1.68430141 |
| 96 | Gingivitis (HP:0000230) | 1.68411910 |
| 97 | Increased IgM level (HP:0003496) | 1.67426715 |
| 98 | Cellulitis (HP:0100658) | 1.66486443 |
| 99 | Glomerulopathy (HP:0100820) | 1.64571491 |
| 100 | Viral hepatitis (HP:0006562) | 1.63666779 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRAK3 | 5.44476409 |
| 2 | RIPK4 | 5.27716596 |
| 3 | BMPR2 | 2.81735124 |
| 4 | MAP2K3 | 2.36255367 |
| 5 | BLK | 2.20866691 |
| 6 | ZAP70 | 2.18947914 |
| 7 | ERBB4 | 2.18010455 |
| 8 | MAP3K14 | 2.13489434 |
| 9 | BMX | 2.09299221 |
| 10 | MST4 | 2.06335867 |
| 11 | IRAK4 | 2.05612778 |
| 12 | TAOK2 | 1.88582027 |
| 13 | TAOK3 | 1.88403569 |
| 14 | PIK3CG | 1.88063814 |
| 15 | PRPF4B | 1.87872219 |
| 16 | CSK | 1.73513287 |
| 17 | MAP3K3 | 1.71186215 |
| 18 | CLK1 | 1.69345921 |
| 19 | TTN | 1.64330036 |
| 20 | EIF2AK1 | 1.62182793 |
| 21 | BTK | 1.61691497 |
| 22 | SIK3 | 1.46557740 |
| 23 | IRAK2 | 1.39783177 |
| 24 | MATK | 1.39076766 |
| 25 | TESK2 | 1.38649754 |
| 26 | FGR | 1.35557395 |
| 27 | EPHB1 | 1.33562425 |
| 28 | MARK3 | 1.32848231 |
| 29 | TYK2 | 1.29028821 |
| 30 | KSR2 | 1.27641151 |
| 31 | TXK | 1.22426512 |
| 32 | TEC | 1.21935883 |
| 33 | HCK | 1.19335984 |
| 34 | IKBKB | 1.17419010 |
| 35 | SYK | 1.16336427 |
| 36 | IRAK1 | 1.15234262 |
| 37 | MYLK | 1.13562387 |
| 38 | JAK3 | 1.02912303 |
| 39 | LYN | 1.02652195 |
| 40 | PTK2B | 1.00703234 |
| 41 | RAF1 | 1.00519410 |
| 42 | TBK1 | 0.98774763 |
| 43 | JAK2 | 0.97065732 |
| 44 | ERN1 | 0.96643218 |
| 45 | PAK1 | 0.95074383 |
| 46 | SCYL2 | 0.94673969 |
| 47 | PBK | 0.94177276 |
| 48 | CSF1R | 0.92875041 |
| 49 | YES1 | 0.92774092 |
| 50 | NME2 | 0.92566969 |
| 51 | STK10 | 0.90635751 |
| 52 | ILK | 0.86326938 |
| 53 | PIM2 | 0.85238708 |
| 54 | JAK1 | 0.84592884 |
| 55 | MOS | 0.84113290 |
| 56 | PAK4 | 0.83248623 |
| 57 | MAP3K1 | 0.82662270 |
| 58 | STK3 | 0.81692475 |
| 59 | MAP3K2 | 0.76459522 |
| 60 | DDR2 | 0.76243101 |
| 61 | FER | 0.74600581 |
| 62 | ARAF | 0.73578395 |
| 63 | GRK7 | 0.71318344 |
| 64 | TRPM7 | 0.67095980 |
| 65 | KSR1 | 0.64591710 |
| 66 | PDK2 | 0.62681162 |
| 67 | STK24 | 0.61224272 |
| 68 | MAP4K1 | 0.60910086 |
| 69 | MAP3K5 | 0.60365202 |
| 70 | FES | 0.58130281 |
| 71 | MAP3K13 | 0.57807471 |
| 72 | MAP3K8 | 0.57604612 |
| 73 | MAP2K1 | 0.56905038 |
| 74 | PDPK1 | 0.55109577 |
| 75 | MAP3K6 | 0.54685404 |
| 76 | RET | 0.53160545 |
| 77 | PDGFRB | 0.51107227 |
| 78 | TGFBR2 | 0.50363522 |
| 79 | GRK6 | 0.50281457 |
| 80 | TAOK1 | 0.48439400 |
| 81 | NEK9 | 0.48202832 |
| 82 | PLK2 | 0.46901139 |
| 83 | CDK6 | 0.45922884 |
| 84 | MAPKAPK3 | 0.45724252 |
| 85 | CDC42BPA | 0.44178681 |
| 86 | TESK1 | 0.43824854 |
| 87 | PDK1 | 0.40606763 |
| 88 | LCK | 0.39386860 |
| 89 | MAPKAPK2 | 0.39153256 |
| 90 | ICK | 0.38863501 |
| 91 | IKBKE | 0.38719113 |
| 92 | GSK3A | 0.38110803 |
| 93 | PRKD1 | 0.37179717 |
| 94 | SIK1 | 0.36724173 |
| 95 | STK4 | 0.35196253 |
| 96 | MAPK12 | 0.35038052 |
| 97 | ABL1 | 0.33076562 |
| 98 | TRIB3 | 0.32487423 |
| 99 | TRIM28 | 0.30313365 |
| 100 | BRSK2 | 0.29344140 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.95126020 |
| 2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.41663129 |
| 3 | Platelet activation_Homo sapiens_hsa04611 | 2.38568478 |
| 4 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.32678782 |
| 5 | Other glycan degradation_Homo sapiens_hsa00511 | 2.28345952 |
| 6 | Leishmaniasis_Homo sapiens_hsa05140 | 2.25175884 |
| 7 | Legionellosis_Homo sapiens_hsa05134 | 2.10229294 |
| 8 | Lysosome_Homo sapiens_hsa04142 | 1.94678856 |
| 9 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.94156338 |
| 10 | Shigellosis_Homo sapiens_hsa05131 | 1.90569835 |
| 11 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.90142520 |
| 12 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.89033259 |
| 13 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.88947464 |
| 14 | Malaria_Homo sapiens_hsa05144 | 1.81015831 |
| 15 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.79218543 |
| 16 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.74949421 |
| 17 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.73077217 |
| 18 | Tuberculosis_Homo sapiens_hsa05152 | 1.71034991 |
| 19 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.53880131 |
| 20 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.52640768 |
| 21 | Salmonella infection_Homo sapiens_hsa05132 | 1.51137049 |
| 22 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.50298833 |
| 23 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.49944844 |
| 24 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.49926020 |
| 25 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.48844339 |
| 26 | Phagosome_Homo sapiens_hsa04145 | 1.47623926 |
| 27 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.45773934 |
| 28 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.45608384 |
| 29 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.42010745 |
| 30 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.40968829 |
| 31 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.37088466 |
| 32 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.36018401 |
| 33 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.34339423 |
| 34 | Pertussis_Homo sapiens_hsa05133 | 1.32190340 |
| 35 | Bladder cancer_Homo sapiens_hsa05219 | 1.31572592 |
| 36 | Influenza A_Homo sapiens_hsa05164 | 1.27092123 |
| 37 | Measles_Homo sapiens_hsa05162 | 1.26320739 |
| 38 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.25743191 |
| 39 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.23640599 |
| 40 | Hepatitis B_Homo sapiens_hsa05161 | 1.22248208 |
| 41 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.17435078 |
| 42 | Apoptosis_Homo sapiens_hsa04210 | 1.16753508 |
| 43 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.14757145 |
| 44 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.13631182 |
| 45 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.12032830 |
| 46 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.10371073 |
| 47 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.09829404 |
| 48 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.03619229 |
| 49 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.03021663 |
| 50 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.96878216 |
| 51 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.96219825 |
| 52 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.95820090 |
| 53 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.95240336 |
| 54 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.95125041 |
| 55 | Galactose metabolism_Homo sapiens_hsa00052 | 0.93049813 |
| 56 | Amoebiasis_Homo sapiens_hsa05146 | 0.92940310 |
| 57 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.92821471 |
| 58 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.90289600 |
| 59 | Endocytosis_Homo sapiens_hsa04144 | 0.85452749 |
| 60 | Endometrial cancer_Homo sapiens_hsa05213 | 0.84445928 |
| 61 | Viral myocarditis_Homo sapiens_hsa05416 | 0.83123014 |
| 62 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.82780035 |
| 63 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.80605574 |
| 64 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.78361558 |
| 65 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.76197291 |
| 66 | Hepatitis C_Homo sapiens_hsa05160 | 0.74636039 |
| 67 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.74014279 |
| 68 | Focal adhesion_Homo sapiens_hsa04510 | 0.72657365 |
| 69 | Glioma_Homo sapiens_hsa05214 | 0.70183153 |
| 70 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.69072339 |
| 71 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.68485087 |
| 72 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.67299592 |
| 73 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.65670892 |
| 74 | Prostate cancer_Homo sapiens_hsa05215 | 0.65578953 |
| 75 | Thyroid cancer_Homo sapiens_hsa05216 | 0.65344136 |
| 76 | Allograft rejection_Homo sapiens_hsa05330 | 0.65126846 |
| 77 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.63642662 |
| 78 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.61416841 |
| 79 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.60772740 |
| 80 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.60490343 |
| 81 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.59592258 |
| 82 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.58093843 |
| 83 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.57618037 |
| 84 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.57050000 |
| 85 | Insulin resistance_Homo sapiens_hsa04931 | 0.56914476 |
| 86 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.56677158 |
| 87 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.56140430 |
| 88 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.55482665 |
| 89 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.55049300 |
| 90 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.54270772 |
| 91 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.52716146 |
| 92 | Prion diseases_Homo sapiens_hsa05020 | 0.51078214 |
| 93 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.51003441 |
| 94 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.50022078 |
| 95 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.48043120 |
| 96 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.47801070 |
| 97 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.47712290 |
| 98 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.47086337 |
| 99 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.44814634 |
| 100 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.43418454 |

