

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | histone H4-K12 acetylation (GO:0043983) | 8.61800956 |
| 2 | phosphorelay signal transduction system (GO:0000160) | 7.97314313 |
| 3 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 7.10311778 |
| 4 | flavonoid metabolic process (GO:0009812) | 5.93502173 |
| 5 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 5.82485470 |
| 6 | heparin metabolic process (GO:0030202) | 5.68521116 |
| 7 | heparin biosynthetic process (GO:0030210) | 5.68521116 |
| 8 | piRNA metabolic process (GO:0034587) | 5.67718996 |
| 9 | neuronal action potential (GO:0019228) | 5.66055475 |
| 10 | myoblast fusion (GO:0007520) | 5.47420006 |
| 11 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 5.41271847 |
| 12 | serotonin metabolic process (GO:0042428) | 5.28374899 |
| 13 | endoderm formation (GO:0001706) | 5.27998535 |
| 14 | primary amino compound metabolic process (GO:1901160) | 5.13716421 |
| 15 | lymph node development (GO:0048535) | 4.92418774 |
| 16 | peripheral nervous system development (GO:0007422) | 4.90803162 |
| 17 | phenylpropanoid metabolic process (GO:0009698) | 4.89841486 |
| 18 | syncytium formation by plasma membrane fusion (GO:0000768) | 4.68468558 |
| 19 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 4.62110275 |
| 20 | cellular response to ATP (GO:0071318) | 4.61034867 |
| 21 | negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) | 4.54477331 |
| 22 | positive regulation of heat generation (GO:0031652) | 4.44418041 |
| 23 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 4.39286826 |
| 24 | positive regulation of icosanoid secretion (GO:0032305) | 4.22924486 |
| 25 | behavioral response to nicotine (GO:0035095) | 4.21256880 |
| 26 | positive regulation of fatty acid transport (GO:2000193) | 4.20980478 |
| 27 | phenol-containing compound catabolic process (GO:0019336) | 4.19423284 |
| 28 | regulation of fever generation (GO:0031620) | 4.17775777 |
| 29 | regulation of female gonad development (GO:2000194) | 4.05697714 |
| 30 | replicative senescence (GO:0090399) | 4.04547623 |
| 31 | protein localization to synapse (GO:0035418) | 3.99402935 |
| 32 | negative regulation of sodium ion transport (GO:0010766) | 3.96148875 |
| 33 | regulation of cell maturation (GO:1903429) | 3.90711397 |
| 34 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 3.84946420 |
| 35 | syncytium formation (GO:0006949) | 3.81984527 |
| 36 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 3.79815197 |
| 37 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 3.79815197 |
| 38 | regulation of feeding behavior (GO:0060259) | 3.79639179 |
| 39 | positive regulation of gastrulation (GO:2000543) | 3.79612833 |
| 40 | synaptic transmission, glutamatergic (GO:0035249) | 3.76048633 |
| 41 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.75840868 |
| 42 | dopaminergic neuron differentiation (GO:0071542) | 3.69889373 |
| 43 | detection of mechanical stimulus involved in sensory perception (GO:0050974) | 3.69825066 |
| 44 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.66183711 |
| 45 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 3.58447944 |
| 46 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 3.58447944 |
| 47 | indole-containing compound metabolic process (GO:0042430) | 3.54270232 |
| 48 | appendage development (GO:0048736) | 3.54194061 |
| 49 | limb development (GO:0060173) | 3.54194061 |
| 50 | membrane depolarization during action potential (GO:0086010) | 3.51614185 |
| 51 | tachykinin receptor signaling pathway (GO:0007217) | 3.49190956 |
| 52 | alanine transport (GO:0032328) | 3.48019834 |
| 53 | glutamate receptor signaling pathway (GO:0007215) | 3.47184719 |
| 54 | regulation of heat generation (GO:0031650) | 3.43425615 |
| 55 | sulfation (GO:0051923) | 3.42439020 |
| 56 | primitive streak formation (GO:0090009) | 3.40761636 |
| 57 | cardiovascular system development (GO:0072358) | 3.36583042 |
| 58 | histone H4-K8 acetylation (GO:0043982) | 3.33482986 |
| 59 | histone H4-K5 acetylation (GO:0043981) | 3.33482986 |
| 60 | regulation of neuron projection regeneration (GO:0070570) | 3.30733578 |
| 61 | regulation of axon regeneration (GO:0048679) | 3.30733578 |
| 62 | hydrogen peroxide biosynthetic process (GO:0050665) | 3.27628232 |
| 63 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 3.25352860 |
| 64 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.20659813 |
| 65 | regulation of catecholamine metabolic process (GO:0042069) | 3.15245213 |
| 66 | regulation of dopamine metabolic process (GO:0042053) | 3.15245213 |
| 67 | regulation of establishment of cell polarity (GO:2000114) | 3.13013444 |
| 68 | regulation of icosanoid secretion (GO:0032303) | 3.12922859 |
| 69 | cytoplasmic mRNA processing body assembly (GO:0033962) | 3.10580364 |
| 70 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 3.09793128 |
| 71 | action potential (GO:0001508) | 3.09383675 |
| 72 | histone H4-K16 acetylation (GO:0043984) | 3.02908415 |
| 73 | positive regulation of prostaglandin secretion (GO:0032308) | 2.99685654 |
| 74 | transmission of nerve impulse (GO:0019226) | 2.92650171 |
| 75 | gene silencing by RNA (GO:0031047) | 2.91873002 |
| 76 | reactive oxygen species biosynthetic process (GO:1903409) | 2.91247030 |
| 77 | regulation of establishment or maintenance of cell polarity (GO:0032878) | 2.89856062 |
| 78 | calcium ion-dependent exocytosis (GO:0017156) | 2.89306047 |
| 79 | protein K48-linked deubiquitination (GO:0071108) | 2.87887216 |
| 80 | neuron cell-cell adhesion (GO:0007158) | 2.86897606 |
| 81 | pyrimidine dimer repair (GO:0006290) | 2.85284326 |
| 82 | behavioral response to ethanol (GO:0048149) | 2.82634176 |
| 83 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.82405427 |
| 84 | positive regulation of axon extension (GO:0045773) | 2.82054713 |
| 85 | indole-containing compound catabolic process (GO:0042436) | 2.81218928 |
| 86 | indolalkylamine catabolic process (GO:0046218) | 2.81218928 |
| 87 | tryptophan catabolic process (GO:0006569) | 2.81218928 |
| 88 | positive regulation of mRNA catabolic process (GO:0061014) | 2.80961056 |
| 89 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.79468411 |
| 90 | organelle disassembly (GO:1903008) | 2.78488974 |
| 91 | interferon-gamma secretion (GO:0072643) | 2.76211531 |
| 92 | locomotory exploration behavior (GO:0035641) | 2.75504007 |
| 93 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.74806539 |
| 94 | branching involved in prostate gland morphogenesis (GO:0060442) | 2.74429393 |
| 95 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 2.73576227 |
| 96 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 2.73520739 |
| 97 | endocardial cushion development (GO:0003197) | 2.72896579 |
| 98 | response to acidic pH (GO:0010447) | 2.72586265 |
| 99 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 2.71497155 |
| 100 | autophagic vacuole fusion (GO:0000046) | 2.69363701 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.76362222 |
| 2 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 5.30012724 |
| 3 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 3.96665374 |
| 4 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.53342451 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 3.47139552 |
| 6 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 3.04086327 |
| 7 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.66958861 |
| 8 | EWS_26573619_Chip-Seq_HEK293_Human | 2.57625032 |
| 9 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 2.43527382 |
| 10 | FUS_26573619_Chip-Seq_HEK293_Human | 2.32099265 |
| 11 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.30549243 |
| 12 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.21544654 |
| 13 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.05284201 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.94590314 |
| 15 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.87227087 |
| 16 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.84822726 |
| 17 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.84610771 |
| 18 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.77778740 |
| 19 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.74458228 |
| 20 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.71902504 |
| 21 | P300_19829295_ChIP-Seq_ESCs_Human | 1.70614207 |
| 22 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.70074842 |
| 23 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.70070515 |
| 24 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.68384389 |
| 25 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.68102060 |
| 26 | STAT3_23295773_ChIP-Seq_U87_Human | 1.67163268 |
| 27 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.66703087 |
| 28 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.66450194 |
| 29 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.66450194 |
| 30 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.66139402 |
| 31 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.66060990 |
| 32 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.59309119 |
| 33 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.52408446 |
| 34 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.52208900 |
| 35 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.50977764 |
| 36 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.49528833 |
| 37 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.48938935 |
| 38 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.43285000 |
| 39 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.42729146 |
| 40 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.41169090 |
| 41 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.41158253 |
| 42 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.41129591 |
| 43 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.38756297 |
| 44 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.38185805 |
| 45 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.37839873 |
| 46 | TCF4_23295773_ChIP-Seq_U87_Human | 1.37015649 |
| 47 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.36690288 |
| 48 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.36331549 |
| 49 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.34111864 |
| 50 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.34111864 |
| 51 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.34047193 |
| 52 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.33171867 |
| 53 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.32962044 |
| 54 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.32085126 |
| 55 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.29824026 |
| 56 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.29148914 |
| 57 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.28325788 |
| 58 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.26387437 |
| 59 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.24848832 |
| 60 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21803854 |
| 61 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.21608432 |
| 62 | AR_25329375_ChIP-Seq_VCAP_Human | 1.21046052 |
| 63 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.20385915 |
| 64 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.19404489 |
| 65 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.18720599 |
| 66 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.17960699 |
| 67 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.17321217 |
| 68 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.16893819 |
| 69 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.12979738 |
| 70 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.12541017 |
| 71 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.12069690 |
| 72 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.11842472 |
| 73 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.11166443 |
| 74 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.10879343 |
| 75 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.10541532 |
| 76 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.10232517 |
| 77 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.09766750 |
| 78 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.09510862 |
| 79 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.08712552 |
| 80 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.08070477 |
| 81 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.06628853 |
| 82 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.03584445 |
| 83 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.02944723 |
| 84 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02204967 |
| 85 | GF1B_26923725_Chip-Seq_HPCs_Mouse | 1.00938008 |
| 86 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.00562764 |
| 87 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.00211180 |
| 88 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.99155360 |
| 89 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.99145462 |
| 90 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.97497457 |
| 91 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 0.96460736 |
| 92 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.95948608 |
| 93 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.95871259 |
| 94 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.95610561 |
| 95 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.95035567 |
| 96 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 0.94871660 |
| 97 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 0.93627055 |
| 98 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.93564406 |
| 99 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.93017707 |
| 100 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.91313282 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001968_abnormal_touch/_nociception | 3.94065207 |
| 2 | MP0009046_muscle_twitch | 3.85697862 |
| 3 | MP0004270_analgesia | 3.64521248 |
| 4 | MP0003880_abnormal_central_pattern | 3.31774318 |
| 5 | MP0002277_abnormal_respiratory_mucosa | 3.20087386 |
| 6 | MP0005423_abnormal_somatic_nervous | 3.17655372 |
| 7 | MP0002822_catalepsy | 2.96449182 |
| 8 | MP0003890_abnormal_embryonic-extraembry | 2.76486609 |
| 9 | MP0009745_abnormal_behavioral_response | 2.70852958 |
| 10 | MP0002064_seizures | 2.65289632 |
| 11 | MP0001486_abnormal_startle_reflex | 2.55478615 |
| 12 | MP0002733_abnormal_thermal_nociception | 2.52987093 |
| 13 | MP0005646_abnormal_pituitary_gland | 2.49744594 |
| 14 | MP0002734_abnormal_mechanical_nocicepti | 2.33768036 |
| 15 | MP0003635_abnormal_synaptic_transmissio | 2.29534177 |
| 16 | MP0008877_abnormal_DNA_methylation | 2.26833086 |
| 17 | MP0002736_abnormal_nociception_after | 2.16862709 |
| 18 | MP0008961_abnormal_basal_metabolism | 2.09423377 |
| 19 | MP0002735_abnormal_chemical_nociception | 1.95523737 |
| 20 | MP0010352_gastrointestinal_tract_polyps | 1.89852219 |
| 21 | MP0004133_heterotaxia | 1.87641141 |
| 22 | MP0002089_abnormal_postnatal_growth/wei | 1.86878230 |
| 23 | MP0002751_abnormal_autonomic_nervous | 1.84573308 |
| 24 | MP0002138_abnormal_hepatobiliary_system | 1.79392245 |
| 25 | MP0003195_calcinosis | 1.77898557 |
| 26 | MP0008872_abnormal_physiological_respon | 1.73695750 |
| 27 | MP0000750_abnormal_muscle_regeneration | 1.73621795 |
| 28 | MP0001346_abnormal_lacrimal_gland | 1.70705182 |
| 29 | MP0002572_abnormal_emotion/affect_behav | 1.67701262 |
| 30 | MP0002272_abnormal_nervous_system | 1.66632812 |
| 31 | MP0001485_abnormal_pinna_reflex | 1.64853256 |
| 32 | MP0001970_abnormal_pain_threshold | 1.58983020 |
| 33 | MP0005248_abnormal_Harderian_gland | 1.56958751 |
| 34 | MP0010030_abnormal_orbit_morphology | 1.55943356 |
| 35 | MP0000751_myopathy | 1.54926856 |
| 36 | MP0002090_abnormal_vision | 1.53353885 |
| 37 | MP0003646_muscle_fatigue | 1.49727585 |
| 38 | MP0005386_behavior/neurological_phenoty | 1.48857282 |
| 39 | MP0004924_abnormal_behavior | 1.48857282 |
| 40 | MP0004145_abnormal_muscle_electrophysio | 1.48113009 |
| 41 | MP0004043_abnormal_pH_regulation | 1.47739771 |
| 42 | MP0003045_fibrosis | 1.45289538 |
| 43 | MP0003633_abnormal_nervous_system | 1.44131341 |
| 44 | MP0002067_abnormal_sensory_capabilities | 1.43565305 |
| 45 | MP0000427_abnormal_hair_cycle | 1.39485663 |
| 46 | MP0001986_abnormal_taste_sensitivity | 1.38304257 |
| 47 | MP0001879_abnormal_lymphatic_vessel | 1.33188438 |
| 48 | MP0003119_abnormal_digestive_system | 1.28252345 |
| 49 | MP0000749_muscle_degeneration | 1.26991567 |
| 50 | MP0005551_abnormal_eye_electrophysiolog | 1.25523108 |
| 51 | MP0002638_abnormal_pupillary_reflex | 1.24980168 |
| 52 | MP0003631_nervous_system_phenotype | 1.18741075 |
| 53 | MP0005671_abnormal_response_to | 1.11933034 |
| 54 | MP0002063_abnormal_learning/memory/cond | 1.11805469 |
| 55 | MP0002234_abnormal_pharynx_morphology | 1.07029852 |
| 56 | MP0002148_abnormal_hypersensitivity_rea | 1.06230209 |
| 57 | MP0004742_abnormal_vestibular_system | 1.04556365 |
| 58 | MP0004142_abnormal_muscle_tone | 1.02982905 |
| 59 | MP0005084_abnormal_gallbladder_morpholo | 1.01712993 |
| 60 | MP0002184_abnormal_innervation | 0.99849397 |
| 61 | MP0003385_abnormal_body_wall | 0.99283701 |
| 62 | MP0001293_anophthalmia | 0.96468647 |
| 63 | MP0001188_hyperpigmentation | 0.93760898 |
| 64 | MP0008775_abnormal_heart_ventricle | 0.92944079 |
| 65 | MP0002693_abnormal_pancreas_physiology | 0.92631974 |
| 66 | MP0001664_abnormal_digestion | 0.88792285 |
| 67 | MP0003718_maternal_effect | 0.87267138 |
| 68 | MP0004134_abnormal_chest_morphology | 0.83477062 |
| 69 | MP0005645_abnormal_hypothalamus_physiol | 0.82931763 |
| 70 | MP0003283_abnormal_digestive_organ | 0.81675598 |
| 71 | MP0003303_peritoneal_inflammation | 0.81482950 |
| 72 | MP0005332_abnormal_amino_acid | 0.80692102 |
| 73 | MP0000428_abnormal_craniofacial_morphol | 0.79228400 |
| 74 | MP0001501_abnormal_sleep_pattern | 0.79013907 |
| 75 | MP0003959_abnormal_lean_body | 0.78657411 |
| 76 | MP0001324_abnormal_eye_pigmentation | 0.78315524 |
| 77 | MP0006292_abnormal_olfactory_placode | 0.77825539 |
| 78 | MP0001440_abnormal_grooming_behavior | 0.73597267 |
| 79 | MP0002069_abnormal_eating/drinking_beha | 0.72428456 |
| 80 | MP0005171_absent_coat_pigmentation | 0.71978547 |
| 81 | MP0006276_abnormal_autonomic_nervous | 0.65170443 |
| 82 | MP0001663_abnormal_digestive_system | 0.65080966 |
| 83 | MP0000631_abnormal_neuroendocrine_gland | 0.64888297 |
| 84 | MP0000230_abnormal_systemic_arterial | 0.64720278 |
| 85 | MP0000613_abnormal_salivary_gland | 0.64469258 |
| 86 | MP0002837_dystrophic_cardiac_calcinosis | 0.64459347 |
| 87 | MP0005195_abnormal_posterior_eye | 0.63873677 |
| 88 | MP0002557_abnormal_social/conspecific_i | 0.63052454 |
| 89 | MP0002882_abnormal_neuron_morphology | 0.61755972 |
| 90 | MP0008875_abnormal_xenobiotic_pharmacok | 0.61725387 |
| 91 | MP0000778_abnormal_nervous_system | 0.60464514 |
| 92 | MP0005075_abnormal_melanosome_morpholog | 0.60160848 |
| 93 | MP0005448_abnormal_energy_balance | 0.59780874 |
| 94 | MP0000955_abnormal_spinal_cord | 0.59686151 |
| 95 | MP0010386_abnormal_urinary_bladder | 0.57947883 |
| 96 | MP0003698_abnormal_male_reproductive | 0.57859889 |
| 97 | MP0002066_abnormal_motor_capabilities/c | 0.57315224 |
| 98 | MP0003632_abnormal_nervous_system | 0.56697239 |
| 99 | MP0003011_delayed_dark_adaptation | 0.55491896 |
| 100 | MP0003137_abnormal_impulse_conducting | 0.54023535 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Slender build (HP:0001533) | 7.05708542 |
| 2 | Inability to walk (HP:0002540) | 4.52051962 |
| 3 | Prominent supraorbital ridges (HP:0000336) | 4.50954849 |
| 4 | Increased number of teeth (HP:0011069) | 4.50358017 |
| 5 | Type II lissencephaly (HP:0007260) | 4.48580524 |
| 6 | Anhidrosis (HP:0000970) | 4.38090676 |
| 7 | Progressive inability to walk (HP:0002505) | 3.80382662 |
| 8 | Stomach cancer (HP:0012126) | 3.73633998 |
| 9 | Hypoplastic ischia (HP:0003175) | 3.71838871 |
| 10 | Autoamputation (HP:0001218) | 3.69821014 |
| 11 | Midline defect of the nose (HP:0004122) | 3.66441233 |
| 12 | Focal motor seizures (HP:0011153) | 3.66264495 |
| 13 | Medial flaring of the eyebrow (HP:0010747) | 3.53640549 |
| 14 | Curly hair (HP:0002212) | 3.53304293 |
| 15 | Gaze-evoked nystagmus (HP:0000640) | 3.47540310 |
| 16 | Amblyopia (HP:0000646) | 3.31039499 |
| 17 | Hyperventilation (HP:0002883) | 3.21279930 |
| 18 | Ventricular fibrillation (HP:0001663) | 3.11169233 |
| 19 | Abnormality of the ischium (HP:0003174) | 3.10855663 |
| 20 | Thick nail (HP:0001805) | 3.09783657 |
| 21 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.07923648 |
| 22 | Mesangial abnormality (HP:0001966) | 3.04415891 |
| 23 | Osteomalacia (HP:0002749) | 2.98833778 |
| 24 | Nephrogenic diabetes insipidus (HP:0009806) | 2.97413939 |
| 25 | Anterior segment dysgenesis (HP:0007700) | 2.95985693 |
| 26 | Fair hair (HP:0002286) | 2.87191996 |
| 27 | Abnormality of secondary sexual hair (HP:0009888) | 2.84454900 |
| 28 | Abnormality of the axillary hair (HP:0100134) | 2.84454900 |
| 29 | Optic nerve hypoplasia (HP:0000609) | 2.80366265 |
| 30 | Gait imbalance (HP:0002141) | 2.79266877 |
| 31 | Relative macrocephaly (HP:0004482) | 2.76395214 |
| 32 | Congenital, generalized hypertrichosis (HP:0004540) | 2.74212941 |
| 33 | Pancreatic cysts (HP:0001737) | 2.73176392 |
| 34 | Cerebellar dysplasia (HP:0007033) | 2.70687342 |
| 35 | Abnormality of the sella turcica (HP:0002679) | 2.70052765 |
| 36 | Partial agenesis of the corpus callosum (HP:0001338) | 2.68614556 |
| 37 | Lissencephaly (HP:0001339) | 2.66074853 |
| 38 | Neoplasm of the adrenal cortex (HP:0100641) | 2.63594505 |
| 39 | Cystic hygroma (HP:0000476) | 2.62118374 |
| 40 | Neuroendocrine neoplasm (HP:0100634) | 2.61517063 |
| 41 | Alveolar cell carcinoma (HP:0006519) | 2.60458691 |
| 42 | Pheochromocytoma (HP:0002666) | 2.60335075 |
| 43 | Congenital primary aphakia (HP:0007707) | 2.58834347 |
| 44 | Tapered finger (HP:0001182) | 2.58781929 |
| 45 | True hermaphroditism (HP:0010459) | 2.53474920 |
| 46 | Broad metatarsal (HP:0001783) | 2.51893012 |
| 47 | Protruding tongue (HP:0010808) | 2.51127416 |
| 48 | Pancreatic fibrosis (HP:0100732) | 2.50172833 |
| 49 | Long nose (HP:0003189) | 2.50163124 |
| 50 | Clumsiness (HP:0002312) | 2.48286767 |
| 51 | Glossoptosis (HP:0000162) | 2.45755038 |
| 52 | Retinal dysplasia (HP:0007973) | 2.45177554 |
| 53 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.41278360 |
| 54 | Abnormality of alanine metabolism (HP:0010916) | 2.39564427 |
| 55 | Hyperalaninemia (HP:0003348) | 2.39564427 |
| 56 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.39564427 |
| 57 | Megalencephaly (HP:0001355) | 2.39560744 |
| 58 | Nephronophthisis (HP:0000090) | 2.39417094 |
| 59 | Furrowed tongue (HP:0000221) | 2.36104432 |
| 60 | Hydroxyprolinuria (HP:0003080) | 2.35523345 |
| 61 | Abnormality of proline metabolism (HP:0010907) | 2.35523345 |
| 62 | Tubular atrophy (HP:0000092) | 2.32780363 |
| 63 | Poor coordination (HP:0002370) | 2.30778034 |
| 64 | Brachycephaly (HP:0000248) | 2.29993300 |
| 65 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.29672542 |
| 66 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.29240794 |
| 67 | Absent/shortened dynein arms (HP:0200106) | 2.29240794 |
| 68 | Genetic anticipation (HP:0003743) | 2.24718734 |
| 69 | Epileptic encephalopathy (HP:0200134) | 2.21778178 |
| 70 | Sclerocornea (HP:0000647) | 2.21000453 |
| 71 | Meningioma (HP:0002858) | 2.18839689 |
| 72 | Generalized hypopigmentation of hair (HP:0011358) | 2.18237590 |
| 73 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.17921779 |
| 74 | High anterior hairline (HP:0009890) | 2.17361043 |
| 75 | Overgrowth (HP:0001548) | 2.16420835 |
| 76 | Vaginal atresia (HP:0000148) | 2.15186496 |
| 77 | Hip contracture (HP:0003273) | 2.14016613 |
| 78 | Genital tract atresia (HP:0001827) | 2.13048964 |
| 79 | Self-mutilation (HP:0000742) | 2.12948504 |
| 80 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.11455428 |
| 81 | Neonatal respiratory distress (HP:0002643) | 2.10143040 |
| 82 | Irregular vertebral endplates (HP:0003301) | 2.07178219 |
| 83 | Autism (HP:0000717) | 2.06697854 |
| 84 | Intellectual disability, profound (HP:0002187) | 2.05626212 |
| 85 | Bone cyst (HP:0012062) | 2.03696718 |
| 86 | Deeply set eye (HP:0000490) | 2.02395931 |
| 87 | Episodic fever (HP:0001954) | 1.98051227 |
| 88 | Hamartoma of the eye (HP:0010568) | 1.95868906 |
| 89 | Poor eye contact (HP:0000817) | 1.93750185 |
| 90 | Chronic bronchitis (HP:0004469) | 1.90078140 |
| 91 | Abnormal auditory evoked potentials (HP:0006958) | 1.88884226 |
| 92 | Meningocele (HP:0002435) | 1.88503192 |
| 93 | Melanocytic nevus (HP:0000995) | 1.87610894 |
| 94 | Preaxial foot polydactyly (HP:0001841) | 1.85118667 |
| 95 | Absent hair (HP:0002298) | 1.84138095 |
| 96 | Focal seizures (HP:0007359) | 1.83841373 |
| 97 | Colon cancer (HP:0003003) | 1.83650102 |
| 98 | Generalized tonic-clonic seizures (HP:0002069) | 1.81400814 |
| 99 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.81345073 |
| 100 | Drooling (HP:0002307) | 1.80335407 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK24 | 6.24561099 |
| 2 | FRK | 4.44496776 |
| 3 | STK3 | 3.14022957 |
| 4 | PNCK | 3.10058864 |
| 5 | TAOK3 | 2.91510357 |
| 6 | ZAK | 2.83838004 |
| 7 | IRAK1 | 2.78694402 |
| 8 | MAPKAPK3 | 2.72537261 |
| 9 | ACVR1B | 2.18466899 |
| 10 | NUAK1 | 1.94253820 |
| 11 | ADRBK1 | 1.88300730 |
| 12 | BMPR1B | 1.86027099 |
| 13 | ADRBK2 | 1.85039198 |
| 14 | MAPK13 | 1.69858639 |
| 15 | SIK1 | 1.61734518 |
| 16 | CDK19 | 1.58970077 |
| 17 | MAP3K13 | 1.55518703 |
| 18 | MAP3K4 | 1.55114238 |
| 19 | MAP2K7 | 1.52441232 |
| 20 | CHUK | 1.51609843 |
| 21 | IRAK2 | 1.50070270 |
| 22 | PINK1 | 1.48498397 |
| 23 | EEF2K | 1.45722725 |
| 24 | FGFR2 | 1.38576375 |
| 25 | TXK | 1.33872638 |
| 26 | NTRK1 | 1.32180706 |
| 27 | VRK2 | 1.26925626 |
| 28 | TEC | 1.22796552 |
| 29 | CSNK1G1 | 1.22185212 |
| 30 | CCNB1 | 1.19690746 |
| 31 | CSNK1G2 | 1.14210783 |
| 32 | SGK2 | 1.13986631 |
| 33 | TAF1 | 1.11366465 |
| 34 | GRK1 | 1.10881017 |
| 35 | MAP4K2 | 1.07875115 |
| 36 | MATK | 1.07679921 |
| 37 | DYRK1A | 1.06010276 |
| 38 | PASK | 1.03531683 |
| 39 | MAPKAPK5 | 0.99915356 |
| 40 | TSSK6 | 0.99772563 |
| 41 | INSRR | 0.99564687 |
| 42 | PRKCG | 0.99442306 |
| 43 | TRPM7 | 0.97731169 |
| 44 | CDK3 | 0.92779407 |
| 45 | DYRK2 | 0.90389572 |
| 46 | MARK1 | 0.89742462 |
| 47 | TGFBR1 | 0.86400101 |
| 48 | IKBKB | 0.85650063 |
| 49 | WNK3 | 0.79899342 |
| 50 | CSNK1G3 | 0.78022610 |
| 51 | ERBB3 | 0.76090120 |
| 52 | VRK1 | 0.74756233 |
| 53 | MAP2K4 | 0.72845637 |
| 54 | PLK1 | 0.71855964 |
| 55 | DAPK1 | 0.70140857 |
| 56 | PTK2B | 0.69424618 |
| 57 | ERBB2 | 0.69271461 |
| 58 | CAMK2B | 0.68786561 |
| 59 | SGK223 | 0.65654536 |
| 60 | SGK494 | 0.65654536 |
| 61 | GRK5 | 0.64041980 |
| 62 | ITK | 0.62370666 |
| 63 | DYRK3 | 0.61467266 |
| 64 | IRAK4 | 0.60680428 |
| 65 | WNK4 | 0.55777028 |
| 66 | PRKCQ | 0.55535569 |
| 67 | PRKAA2 | 0.55309260 |
| 68 | CSF1R | 0.54519910 |
| 69 | MELK | 0.54102040 |
| 70 | STK11 | 0.53299966 |
| 71 | CAMK1G | 0.52454214 |
| 72 | SIK2 | 0.51087250 |
| 73 | PRKAA1 | 0.50525367 |
| 74 | TIE1 | 0.50013109 |
| 75 | PAK3 | 0.45352128 |
| 76 | CAMK2A | 0.45194542 |
| 77 | CHEK2 | 0.44676695 |
| 78 | PRKCE | 0.43743087 |
| 79 | PBK | 0.43630938 |
| 80 | RPS6KA6 | 0.42338829 |
| 81 | SGK3 | 0.41808097 |
| 82 | PHKG1 | 0.40964443 |
| 83 | PHKG2 | 0.40964443 |
| 84 | TYRO3 | 0.38936245 |
| 85 | EIF2AK2 | 0.38490640 |
| 86 | RPS6KA5 | 0.38488798 |
| 87 | CDC7 | 0.37542984 |
| 88 | PRKACG | 0.35681497 |
| 89 | OBSCN | 0.34882530 |
| 90 | CSNK1D | 0.33846254 |
| 91 | STK38L | 0.33821736 |
| 92 | NTRK2 | 0.29710405 |
| 93 | PLK3 | 0.29291705 |
| 94 | PKN1 | 0.29079023 |
| 95 | GRK6 | 0.28849442 |
| 96 | AKT2 | 0.28405259 |
| 97 | RPS6KA2 | 0.28157585 |
| 98 | PRKACA | 0.28095371 |
| 99 | CDK8 | 0.27988061 |
| 100 | EPHB2 | 0.27951571 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nicotine addiction_Homo sapiens_hsa05033 | 4.42793164 |
| 2 | Long-term depression_Homo sapiens_hsa04730 | 3.21130824 |
| 3 | Asthma_Homo sapiens_hsa05310 | 3.11875194 |
| 4 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.49035475 |
| 5 | Circadian entrainment_Homo sapiens_hsa04713 | 2.48282858 |
| 6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.43399331 |
| 7 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.27801525 |
| 8 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.21267134 |
| 9 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.04735176 |
| 10 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.91369164 |
| 11 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.89693193 |
| 12 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.87429267 |
| 13 | Taste transduction_Homo sapiens_hsa04742 | 1.85550641 |
| 14 | Olfactory transduction_Homo sapiens_hsa04740 | 1.83649387 |
| 15 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.77147628 |
| 16 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.76158704 |
| 17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.70578931 |
| 18 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.62732556 |
| 19 | Allograft rejection_Homo sapiens_hsa05330 | 1.59902989 |
| 20 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.58704981 |
| 21 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.55742195 |
| 22 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.53288512 |
| 23 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.48396371 |
| 24 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.46712385 |
| 25 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.43727499 |
| 26 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.39788532 |
| 27 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.38359668 |
| 28 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.36440337 |
| 29 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.34694357 |
| 30 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.34491807 |
| 31 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.30025399 |
| 32 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.29041836 |
| 33 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.28929264 |
| 34 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.27971238 |
| 35 | Salivary secretion_Homo sapiens_hsa04970 | 1.26479585 |
| 36 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.26199474 |
| 37 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.18578548 |
| 38 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.17073841 |
| 39 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.16940553 |
| 40 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.16064716 |
| 41 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.13073879 |
| 42 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.10148075 |
| 43 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.08934334 |
| 44 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.08526886 |
| 45 | Retinol metabolism_Homo sapiens_hsa00830 | 1.08481149 |
| 46 | Morphine addiction_Homo sapiens_hsa05032 | 1.07398927 |
| 47 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 1.07187009 |
| 48 | Renin secretion_Homo sapiens_hsa04924 | 1.07075430 |
| 49 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.05770920 |
| 50 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.00308249 |
| 51 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.98319212 |
| 52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.97414975 |
| 53 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.95840120 |
| 54 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.93774644 |
| 55 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.93325082 |
| 56 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.91674314 |
| 57 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.90573017 |
| 58 | Histidine metabolism_Homo sapiens_hsa00340 | 0.87717776 |
| 59 | RNA polymerase_Homo sapiens_hsa03020 | 0.86471360 |
| 60 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.86151161 |
| 61 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.84979797 |
| 62 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.83764190 |
| 63 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.82752844 |
| 64 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.78220010 |
| 65 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.73778970 |
| 66 | ABC transporters_Homo sapiens_hsa02010 | 0.73174228 |
| 67 | GABAergic synapse_Homo sapiens_hsa04727 | 0.69368036 |
| 68 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.63235908 |
| 69 | Cocaine addiction_Homo sapiens_hsa05030 | 0.62738751 |
| 70 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.59979274 |
| 71 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.57742968 |
| 72 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.56752615 |
| 73 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.54819077 |
| 74 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.52031406 |
| 75 | Insulin secretion_Homo sapiens_hsa04911 | 0.51466116 |
| 76 | Long-term potentiation_Homo sapiens_hsa04720 | 0.46906777 |
| 77 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.43667891 |
| 78 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.41619880 |
| 79 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.39844774 |
| 80 | Alzheimers disease_Homo sapiens_hsa05010 | 0.39721136 |
| 81 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.39373823 |
| 82 | Phototransduction_Homo sapiens_hsa04744 | 0.38699040 |
| 83 | Viral myocarditis_Homo sapiens_hsa05416 | 0.37619002 |
| 84 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.37571632 |
| 85 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.36622982 |
| 86 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.36206208 |
| 87 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.35934995 |
| 88 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.35869915 |
| 89 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.32426370 |
| 90 | Melanoma_Homo sapiens_hsa05218 | 0.31385875 |
| 91 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.30681023 |
| 92 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.30516859 |
| 93 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.30207748 |
| 94 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.29504547 |
| 95 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.29374761 |
| 96 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.28332517 |
| 97 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.27196843 |
| 98 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.26294824 |
| 99 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.25059497 |
| 100 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.25026273 |

