Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of vitamin D biosynthetic process (GO:0060556) | 6.56201015 |
2 | regulation of vitamin metabolic process (GO:0030656) | 5.20088045 |
3 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 4.65095115 |
4 | regulation of cytokine secretion involved in immune response (GO:0002739) | 4.42978787 |
5 | regulation of chemokine biosynthetic process (GO:0045073) | 4.37178290 |
6 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 4.35543166 |
7 | negative regulation of interleukin-12 production (GO:0032695) | 4.24273675 |
8 | regulation of chronic inflammatory response (GO:0002676) | 4.07401440 |
9 | NIK/NF-kappaB signaling (GO:0038061) | 4.04061364 |
10 | wound healing, spreading of epidermal cells (GO:0035313) | 3.97360638 |
11 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 3.91689755 |
12 | activation of MAPKKK activity (GO:0000185) | 3.77062777 |
13 | neutrophil activation involved in immune response (GO:0002283) | 3.65997921 |
14 | regulation of heat generation (GO:0031650) | 3.63087616 |
15 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 3.62653921 |
16 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 3.61820937 |
17 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 3.56555427 |
18 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.53289799 |
19 | positive regulation of nitric oxide biosynthetic process (GO:0045429) | 3.47321814 |
20 | cell adhesion mediated by integrin (GO:0033627) | 3.46779264 |
21 | regulation of nitric oxide biosynthetic process (GO:0045428) | 3.43864959 |
22 | T-helper 1 type immune response (GO:0042088) | 3.41744975 |
23 | positive regulation of p38MAPK cascade (GO:1900745) | 3.40437658 |
24 | positive regulation of osteoblast proliferation (GO:0033690) | 3.39199252 |
25 | oligosaccharide catabolic process (GO:0009313) | 3.38664136 |
26 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 3.36733460 |
27 | wound healing, spreading of cells (GO:0044319) | 3.31547662 |
28 | negative regulation of lipid storage (GO:0010888) | 3.27493403 |
29 | protein localization to endosome (GO:0036010) | 3.24533532 |
30 | germinal center formation (GO:0002467) | 3.23320826 |
31 | glycosphingolipid catabolic process (GO:0046479) | 3.22487631 |
32 | myeloid dendritic cell differentiation (GO:0043011) | 3.22075813 |
33 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.20350022 |
34 | cellular response to lipopolysaccharide (GO:0071222) | 3.20033948 |
35 | endothelial cell morphogenesis (GO:0001886) | 3.15566474 |
36 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.14965619 |
37 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 3.14951535 |
38 | lymph vessel development (GO:0001945) | 3.13757589 |
39 | response to muramyl dipeptide (GO:0032495) | 3.13716238 |
40 | virion attachment to host cell (GO:0019062) | 3.12961168 |
41 | adhesion of symbiont to host cell (GO:0044650) | 3.12961168 |
42 | regulation of immunoglobulin secretion (GO:0051023) | 3.10535803 |
43 | hemidesmosome assembly (GO:0031581) | 3.09407831 |
44 | regulation of chemokine secretion (GO:0090196) | 3.08594132 |
45 | regulation of interferon-alpha production (GO:0032647) | 3.07446741 |
46 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.05941113 |
47 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.05941113 |
48 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.05941113 |
49 | modulation by symbiont of host immune response (GO:0052553) | 3.05941113 |
50 | positive regulation by symbiont of host defense response (GO:0052509) | 3.05941113 |
51 | modulation by symbiont of host defense response (GO:0052031) | 3.05941113 |
52 | regulation of heterotypic cell-cell adhesion (GO:0034114) | 3.05405364 |
53 | cellular response to molecule of bacterial origin (GO:0071219) | 3.04623660 |
54 | positive regulation of acute inflammatory response (GO:0002675) | 3.01515512 |
55 | regulation of NF-kappaB import into nucleus (GO:0042345) | 3.00446391 |
56 | low-density lipoprotein particle clearance (GO:0034383) | 2.96502623 |
57 | monocyte chemotaxis (GO:0002548) | 2.96204393 |
58 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 2.95462255 |
59 | positive regulation of astrocyte differentiation (GO:0048711) | 2.93991544 |
60 | positive regulation of transcription factor import into nucleus (GO:0042993) | 2.93459815 |
61 | response to laminar fluid shear stress (GO:0034616) | 2.91985890 |
62 | positive regulation of chemokine secretion (GO:0090197) | 2.88019924 |
63 | cellular extravasation (GO:0045123) | 2.86497441 |
64 | glycolipid catabolic process (GO:0019377) | 2.86251526 |
65 | skin morphogenesis (GO:0043589) | 2.86177053 |
66 | eosinophil chemotaxis (GO:0048245) | 2.85461956 |
67 | adhesion of symbiont to host (GO:0044406) | 2.85086675 |
68 | microglial cell activation (GO:0001774) | 2.83852734 |
69 | positive regulation of hair cycle (GO:0042635) | 2.83000533 |
70 | positive regulation of hair follicle development (GO:0051798) | 2.83000533 |
71 | cellular response to type I interferon (GO:0071357) | 2.82399160 |
72 | type I interferon signaling pathway (GO:0060337) | 2.82399160 |
73 | regulation of toll-like receptor 4 signaling pathway (GO:0034143) | 2.81744921 |
74 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.81677970 |
75 | mesodermal cell differentiation (GO:0048333) | 2.80982172 |
76 | response to type I interferon (GO:0034340) | 2.78334212 |
77 | cellular response to arsenic-containing substance (GO:0071243) | 2.76903910 |
78 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.76512872 |
79 | defense response to protozoan (GO:0042832) | 2.76368582 |
80 | positive regulation of macrophage differentiation (GO:0045651) | 2.75794405 |
81 | response to peptidoglycan (GO:0032494) | 2.75734272 |
82 | macrophage activation (GO:0042116) | 2.73565860 |
83 | positive regulation of type 2 immune response (GO:0002830) | 2.72976261 |
84 | cellular response to nicotine (GO:0071316) | 2.72975622 |
85 | substrate-dependent cell migration (GO:0006929) | 2.72662309 |
86 | cellular response to thyroid hormone stimulus (GO:0097067) | 2.71281559 |
87 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.70827765 |
88 | regulation of vascular endothelial growth factor production (GO:0010574) | 2.70466513 |
89 | response to progesterone (GO:0032570) | 2.69164149 |
90 | decidualization (GO:0046697) | 2.69120931 |
91 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.68441072 |
92 | cellular response to biotic stimulus (GO:0071216) | 2.67389667 |
93 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.67274431 |
94 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.65956946 |
95 | eosinophil migration (GO:0072677) | 2.65870137 |
96 | regulation of mononuclear cell migration (GO:0071675) | 2.64394593 |
97 | atrioventricular valve morphogenesis (GO:0003181) | 2.63931293 |
98 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.63816415 |
99 | positive regulation of chemokine biosynthetic process (GO:0045080) | 2.62933430 |
100 | regulation of interleukin-6 production (GO:0032675) | 2.62740335 |
101 | macrophage activation involved in immune response (GO:0002281) | 2.61514791 |
102 | tyrosine phosphorylation of STAT protein (GO:0007260) | 2.60121046 |
103 | lymphangiogenesis (GO:0001946) | 2.59425593 |
104 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.58599832 |
105 | membrane lipid catabolic process (GO:0046466) | 2.57698604 |
106 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.57516453 |
107 | modulation by symbiont of host cellular process (GO:0044068) | 2.55557506 |
108 | myeloid dendritic cell activation (GO:0001773) | 2.55032334 |
109 | regulation of macrophage cytokine production (GO:0010935) | 2.54978970 |
110 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.54767690 |
111 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.54315531 |
112 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.53321588 |
113 | establishment of endothelial barrier (GO:0061028) | 2.53198317 |
114 | endothelium development (GO:0003158) | 2.52615176 |
115 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.51997656 |
116 | sphingosine metabolic process (GO:0006670) | 2.50624981 |
117 | collagen fibril organization (GO:0030199) | 2.50331648 |
118 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 2.50042022 |
119 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.49678284 |
120 | granulocyte activation (GO:0036230) | 2.49452564 |
121 | regulation of cholesterol storage (GO:0010885) | 2.49387601 |
122 | lung vasculature development (GO:0060426) | 2.48594553 |
123 | neutrophil activation (GO:0042119) | 2.48462693 |
124 | regulation of mast cell degranulation (GO:0043304) | 2.48119372 |
125 | glial cell migration (GO:0008347) | 2.47514151 |
126 | lipoxygenase pathway (GO:0019372) | 2.47025417 |
127 | positive regulation of interferon-alpha production (GO:0032727) | 2.47012575 |
128 | detection of molecule of bacterial origin (GO:0032490) | 2.46887451 |
129 | ceramide catabolic process (GO:0046514) | 2.45326600 |
130 | positive regulation of T-helper cell differentiation (GO:0045624) | 2.45298562 |
131 | positive regulation of chemokine production (GO:0032722) | 2.45202871 |
132 | response to fluid shear stress (GO:0034405) | 2.44086482 |
133 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.43805331 |
134 | lung lobe morphogenesis (GO:0060463) | 2.43565453 |
135 | positive regulation of odontogenesis (GO:0042482) | 2.41569853 |
136 | regulation of podosome assembly (GO:0071801) | 2.41242885 |
137 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.40265367 |
138 | surfactant homeostasis (GO:0043129) | 2.39624930 |
139 | regulation of p38MAPK cascade (GO:1900744) | 2.39217294 |
140 | negative regulation of mast cell activation (GO:0033004) | 2.38266833 |
141 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.37603595 |
142 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.36675893 |
143 | hyaluronan catabolic process (GO:0030214) | 2.36464378 |
144 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.35758662 |
145 | angiogenesis involved in wound healing (GO:0060055) | 2.35330645 |
146 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.35096412 |
147 | positive regulation of mast cell degranulation (GO:0043306) | 2.34945979 |
148 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.34945979 |
149 | regulation of monocyte chemotaxis (GO:0090025) | 2.34856359 |
150 | keratan sulfate catabolic process (GO:0042340) | 2.33654072 |
151 | blood vessel remodeling (GO:0001974) | 2.30716784 |
152 | positive regulation of leukocyte degranulation (GO:0043302) | 2.29078997 |
153 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.28636918 |
154 | regulation of endothelial cell differentiation (GO:0045601) | 2.28139189 |
155 | chondrocyte proliferation (GO:0035988) | 2.27984227 |
156 | fibroblast migration (GO:0010761) | 2.27874107 |
157 | endodermal cell differentiation (GO:0035987) | 2.27804379 |
158 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.27715295 |
159 | regulation of fever generation (GO:0031620) | 2.26174428 |
160 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.24509190 |
161 | response to interferon-alpha (GO:0035455) | 2.24479971 |
162 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.22995040 |
163 | response to host immune response (GO:0052572) | 2.22995040 |
164 | positive regulation of interleukin-6 production (GO:0032755) | 2.22419811 |
165 | immunoglobulin mediated immune response (GO:0016064) | 2.20200713 |
166 | positive regulation of heat generation (GO:0031652) | 2.20117324 |
167 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.19609238 |
168 | response to host (GO:0075136) | 2.19609238 |
169 | response to host defenses (GO:0052200) | 2.19609238 |
170 | response to interferon-beta (GO:0035456) | 2.19457354 |
171 | regulation of cell migration involved in sprouting angiogenesis (GO:0090049) | 2.19274642 |
172 | morphogenesis of an endothelium (GO:0003159) | 2.19055544 |
173 | endothelial tube morphogenesis (GO:0061154) | 2.19055544 |
174 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.18883550 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 6.92281017 |
2 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 4.86600076 |
3 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 4.78127521 |
4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.41918853 |
5 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.77582125 |
6 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.68065885 |
7 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 3.13467012 |
8 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.12901119 |
9 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.01276306 |
10 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.89416484 |
11 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 2.81875525 |
12 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.56218736 |
13 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.40653499 |
14 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 2.33216530 |
15 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.32143416 |
16 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.31199794 |
17 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.25622335 |
18 | * ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.17475353 |
19 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.16583883 |
20 | * Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.15545216 |
21 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.10401987 |
22 | * MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.08239849 |
23 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.06275304 |
24 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 2.05259985 |
25 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 2.05259985 |
26 | * CJUN_26792858_Chip-Seq_BT549_Human | 2.02471555 |
27 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.02359953 |
28 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.99565008 |
29 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.97671792 |
30 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.80342284 |
31 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.79584318 |
32 | * NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.78811759 |
33 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.78254742 |
34 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.77562661 |
35 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.74221719 |
36 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.71241588 |
37 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.67959139 |
38 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.65205525 |
39 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.64727116 |
40 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.61860809 |
41 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.59095879 |
42 | * STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.53730473 |
43 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.53718427 |
44 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.53122531 |
45 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.49001389 |
46 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.48837611 |
47 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.48518166 |
48 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.46912694 |
49 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.45543154 |
50 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.44897022 |
51 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.41674560 |
52 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.41674560 |
53 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.38848246 |
54 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.37812987 |
55 | * FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.37104112 |
56 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.36699020 |
57 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.36598715 |
58 | * P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.34178717 |
59 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.33216030 |
60 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.30360613 |
61 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.28380532 |
62 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.27001208 |
63 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.22869077 |
64 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.22743988 |
65 | KDM2B_26808549_Chip-Seq_K562_Human | 1.21934281 |
66 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.21648025 |
67 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.21329239 |
68 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.20802065 |
69 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.20515263 |
70 | SPI1_23127762_ChIP-Seq_K562_Human | 1.20413632 |
71 | MYC_22102868_ChIP-Seq_BL_Human | 1.19797891 |
72 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.19389545 |
73 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.19385582 |
74 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.18800285 |
75 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.18690604 |
76 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.18496594 |
77 | * UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.17703314 |
78 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.17626500 |
79 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.15723453 |
80 | * STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.15687196 |
81 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.14652789 |
82 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.14319549 |
83 | * RUNX_20019798_ChIP-Seq_JUKART_Human | 1.12089899 |
84 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.11422686 |
85 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.11045687 |
86 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.09744399 |
87 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.09725772 |
88 | ATF3_27146783_Chip-Seq_COLON_Human | 1.09645346 |
89 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.09021163 |
90 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.08912082 |
91 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.07585582 |
92 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.07243963 |
93 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.07238907 |
94 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.07201125 |
95 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.06884473 |
96 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06855417 |
97 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.06522682 |
98 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.06276998 |
99 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.06143618 |
100 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.01449306 |
101 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.00716611 |
102 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.99501596 |
103 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.98538478 |
104 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.97623784 |
105 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.97321303 |
106 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.97173202 |
107 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 0.96954789 |
108 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.96771044 |
109 | * STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.96223689 |
110 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.96101108 |
111 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.96038947 |
112 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.95610708 |
113 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.94104727 |
114 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.93816153 |
115 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.93693444 |
116 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.93284612 |
117 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92024084 |
118 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.91818233 |
119 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.91116867 |
120 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.90968202 |
121 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.89987033 |
122 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.89987033 |
123 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.89987033 |
124 | MAF_26560356_Chip-Seq_TH1_Human | 0.89956714 |
125 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.89600620 |
126 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.89495661 |
127 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.88533796 |
128 | KLF5_25053715_ChIP-Seq_YYC3_Human | 0.86028015 |
129 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.85836907 |
130 | MYB_26560356_Chip-Seq_TH2_Human | 0.85027693 |
131 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.83801323 |
132 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.83679991 |
133 | * GATA2_19941826_ChIP-Seq_K562_Human | 0.80196714 |
134 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.78592294 |
135 | * TP63_23658742_ChIP-Seq_EP156T_Human | 0.77501567 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0009840_abnormal_foam_cell | 3.45012943 |
2 | MP0003724_increased_susceptibility_to | 3.34135646 |
3 | MP0008438_abnormal_cutaneous_collagen | 3.28171039 |
4 | MP0010368_abnormal_lymphatic_system | 3.03457124 |
5 | MP0003436_decreased_susceptibility_to | 2.79107265 |
6 | MP0005275_abnormal_skin_tensile | 2.77067369 |
7 | MP0003279_aneurysm | 2.44391622 |
8 | MP0003303_peritoneal_inflammation | 2.44227631 |
9 | MP0003566_abnormal_cell_adhesion | 2.33777756 |
10 | MP0005451_abnormal_body_composition | 2.29827291 |
11 | MP0001879_abnormal_lymphatic_vessel | 2.25572077 |
12 | MP0000343_altered_response_to | 2.25070254 |
13 | MP0002148_abnormal_hypersensitivity_rea | 2.22961052 |
14 | MP0001533_abnormal_skeleton_physiology | 2.22892834 |
15 | MP0002139_abnormal_hepatobiliary_system | 2.22076327 |
16 | MP0005023_abnormal_wound_healing | 2.18346816 |
17 | MP0006054_spinal_hemorrhage | 2.13650611 |
18 | MP0004272_abnormal_basement_membrane | 2.10655477 |
19 | MP0009785_altered_susceptibility_to | 2.10514579 |
20 | MP0005503_abnormal_tendon_morphology | 2.07000875 |
21 | MP0003828_pulmonary_edema | 1.99552250 |
22 | MP0003705_abnormal_hypodermis_morpholog | 1.89243474 |
23 | MP0001958_emphysema | 1.87199175 |
24 | MP0005164_abnormal_response_to | 1.86357701 |
25 | MP0002419_abnormal_innate_immunity | 1.86092066 |
26 | MP0010352_gastrointestinal_tract_polyps | 1.84988932 |
27 | MP0002332_abnormal_exercise_endurance | 1.81686632 |
28 | MP0002254_reproductive_system_inflammat | 1.77575297 |
29 | MP0001835_abnormal_antigen_presentation | 1.77202029 |
30 | MP0005390_skeleton_phenotype | 1.73201042 |
31 | MP0002933_joint_inflammation | 1.70709690 |
32 | MP0003300_gastrointestinal_ulcer | 1.70694245 |
33 | MP0003191_abnormal_cellular_cholesterol | 1.68968232 |
34 | MP0001853_heart_inflammation | 1.65545107 |
35 | MP0001542_abnormal_bone_strength | 1.64718860 |
36 | MP0003453_abnormal_keratinocyte_physiol | 1.61359022 |
37 | MP0003448_altered_tumor_morphology | 1.60768921 |
38 | MP0008004_abnormal_stomach_pH | 1.60592206 |
39 | MP0002060_abnormal_skin_morphology | 1.60510118 |
40 | MP0004883_abnormal_blood_vessel | 1.60253497 |
41 | MP0005000_abnormal_immune_tolerance | 1.59224706 |
42 | MP0003172_abnormal_lysosome_physiology | 1.57759624 |
43 | MP0009278_abnormal_bone_marrow | 1.57719688 |
44 | MP0000604_amyloidosis | 1.55920416 |
45 | MP0004510_myositis | 1.52472788 |
46 | MP0001851_eye_inflammation | 1.50883987 |
47 | MP0005167_abnormal_blood-brain_barrier | 1.50794012 |
48 | MP0000858_altered_metastatic_potential | 1.50096487 |
49 | MP0002998_abnormal_bone_remodeling | 1.49306718 |
50 | MP0004947_skin_inflammation | 1.47851671 |
51 | MP0003091_abnormal_cell_migration | 1.44229240 |
52 | MP0005671_abnormal_response_to | 1.42873663 |
53 | MP0005623_abnormal_meninges_morphology | 1.42221238 |
54 | MP0000767_abnormal_smooth_muscle | 1.41251613 |
55 | MP0002295_abnormal_pulmonary_circulatio | 1.40652084 |
56 | MP0005025_abnormal_response_to | 1.40149723 |
57 | MP0005508_abnormal_skeleton_morphology | 1.38848917 |
58 | MP0009764_decreased_sensitivity_to | 1.38642253 |
59 | MP0002405_respiratory_system_inflammati | 1.38241453 |
60 | MP0003045_fibrosis | 1.35100332 |
61 | MP0003806_abnormal_nucleotide_metabolis | 1.34946605 |
62 | MP0005387_immune_system_phenotype | 1.33308806 |
63 | MP0001790_abnormal_immune_system | 1.33308806 |
64 | MP0000249_abnormal_blood_vessel | 1.32901648 |
65 | MP0003075_altered_response_to | 1.31786296 |
66 | MP0000465_gastrointestinal_hemorrhage | 1.31694618 |
67 | MP0002452_abnormal_antigen_presenting | 1.31682482 |
68 | MP0010155_abnormal_intestine_physiology | 1.28923360 |
69 | MP0002282_abnormal_trachea_morphology | 1.24749953 |
70 | MP0002877_abnormal_melanocyte_morpholog | 1.23530212 |
71 | MP0006082_CNS_inflammation | 1.22292058 |
72 | MP0005166_decreased_susceptibility_to | 1.19735004 |
73 | MP0005076_abnormal_cell_differentiation | 1.18601361 |
74 | MP0003656_abnormal_erythrocyte_physiolo | 1.15758608 |
75 | MP0005397_hematopoietic_system_phenotyp | 1.14358627 |
76 | MP0001545_abnormal_hematopoietic_system | 1.14358627 |
77 | MP0000685_abnormal_immune_system | 1.13702874 |
78 | MP0003941_abnormal_skin_development | 1.11995070 |
79 | MP0000750_abnormal_muscle_regeneration | 1.11018328 |
80 | MP0005464_abnormal_platelet_physiology | 1.08247878 |
81 | MP0002723_abnormal_immune_serum | 1.07969524 |
82 | MP0005165_increased_susceptibility_to | 1.06354585 |
83 | MP0004808_abnormal_hematopoietic_stem | 1.05332618 |
84 | MP0001845_abnormal_inflammatory_respons | 1.05306045 |
85 | MP0003795_abnormal_bone_structure | 1.05277729 |
86 | MP0009384_cardiac_valve_regurgitation | 1.03556341 |
87 | MP0010234_abnormal_vibrissa_follicle | 1.03216230 |
88 | MP0001819_abnormal_immune_cell | 1.00050060 |
89 | MP0002420_abnormal_adaptive_immunity | 0.99982610 |
90 | MP0001800_abnormal_humoral_immune | 0.98598730 |
91 | MP0004782_abnormal_surfactant_physiolog | 0.98426659 |
92 | MP0005257_abnormal_intraocular_pressure | 0.97131033 |
93 | MP0002138_abnormal_hepatobiliary_system | 0.96646249 |
94 | MP0003690_abnormal_glial_cell | 0.96072918 |
95 | MP0005310_abnormal_salivary_gland | 0.95189389 |
96 | MP0001216_abnormal_epidermal_layer | 0.94585514 |
97 | MP0001849_ear_inflammation | 0.93952842 |
98 | MP0005058_abnormal_lysosome_morphology | 0.92894576 |
99 | MP0003329_amyloid_beta_deposits | 0.92818163 |
100 | MP0008260_abnormal_autophagy | 0.92230341 |
101 | MP0005595_abnormal_vascular_smooth | 0.92149974 |
102 | MP0002896_abnormal_bone_mineralization | 0.91073235 |
103 | MP0000516_abnormal_urinary_system | 0.87347714 |
104 | MP0005367_renal/urinary_system_phenotyp | 0.87347714 |
105 | MP0001243_abnormal_dermal_layer | 0.84094365 |
106 | MP0001614_abnormal_blood_vessel | 0.81631197 |
107 | MP0003950_abnormal_plasma_membrane | 0.81581737 |
108 | MP0009763_increased_sensitivity_to | 0.79946401 |
109 | MP0002113_abnormal_skeleton_development | 0.79247839 |
110 | MP0001727_abnormal_embryo_implantation | 0.77596339 |
111 | MP0000716_abnormal_immune_system | 0.77537090 |
112 | MP0001881_abnormal_mammary_gland | 0.76257110 |
113 | MP0008469_abnormal_protein_level | 0.76057875 |
114 | MP0009765_abnormal_xenobiotic_induced | 0.75963229 |
115 | MP0002133_abnormal_respiratory_system | 0.75128761 |
116 | MP0005388_respiratory_system_phenotype | 0.75128761 |
117 | MP0005197_abnormal_uvea_morphology | 0.75029437 |
118 | MP0000163_abnormal_cartilage_morphology | 0.74485474 |
119 | MP0001191_abnormal_skin_condition | 0.74031967 |
120 | MP0009333_abnormal_splenocyte_physiolog | 0.73909033 |
121 | MP0003195_calcinosis | 0.70668070 |
122 | MP0008874_decreased_physiological_sensi | 0.69196302 |
123 | MP0000920_abnormal_myelination | 0.68173110 |
124 | MP0004233_abnormal_muscle_weight | 0.67234954 |
125 | MP0001663_abnormal_digestive_system | 0.65937426 |
126 | MP0002796_impaired_skin_barrier | 0.63126222 |
127 | MP0010307_abnormal_tumor_latency | 0.62609419 |
128 | MP0004858_abnormal_nervous_system | 0.61566826 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of glycolipid metabolism (HP:0010969) | 6.73601395 |
2 | Abnormality of liposaccharide metabolism (HP:0010968) | 6.73601395 |
3 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 6.73601395 |
4 | Loss of speech (HP:0002371) | 4.24801485 |
5 | Premature rupture of membranes (HP:0001788) | 4.06835248 |
6 | Nuclear cataract (HP:0100018) | 3.99353532 |
7 | Neurofibrillary tangles (HP:0002185) | 3.91563331 |
8 | Eczematoid dermatitis (HP:0000976) | 3.73821992 |
9 | Atrophic scars (HP:0001075) | 3.68365061 |
10 | Disinhibition (HP:0000734) | 3.67273917 |
11 | Recurrent abscess formation (HP:0002722) | 3.48640005 |
12 | Protrusio acetabuli (HP:0003179) | 3.47674785 |
13 | Vascular tortuosity (HP:0004948) | 3.31956541 |
14 | Interstitial pulmonary disease (HP:0006530) | 3.31046912 |
15 | Abnormality of polysaccharide metabolism (HP:0011012) | 3.29353461 |
16 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 3.29353461 |
17 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 3.29353461 |
18 | Aortic dissection (HP:0002647) | 3.15970153 |
19 | Aortic aneurysm (HP:0004942) | 3.06282603 |
20 | Arterial tortuosity (HP:0005116) | 3.05877041 |
21 | Cervical subluxation (HP:0003308) | 3.01617705 |
22 | Vertebral compression fractures (HP:0002953) | 2.99718211 |
23 | Cerebral inclusion bodies (HP:0100314) | 2.98869668 |
24 | Cerebral aneurysm (HP:0004944) | 2.98683025 |
25 | Myositis (HP:0100614) | 2.95178016 |
26 | Recurrent bacterial skin infections (HP:0005406) | 2.95015854 |
27 | Orchitis (HP:0100796) | 2.94764482 |
28 | Hematochezia (HP:0002573) | 2.89101441 |
29 | Osteolytic defects of the hand bones (HP:0009699) | 2.88002545 |
30 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.88002545 |
31 | Autoimmune thrombocytopenia (HP:0001973) | 2.86559148 |
32 | Mutism (HP:0002300) | 2.85549268 |
33 | Systemic lupus erythematosus (HP:0002725) | 2.85224806 |
34 | Apathy (HP:0000741) | 2.84102033 |
35 | Stomatitis (HP:0010280) | 2.77539321 |
36 | Amyloidosis (HP:0011034) | 2.76906471 |
37 | Onycholysis (HP:0001806) | 2.74302584 |
38 | Increased serum ferritin (HP:0003281) | 2.73032250 |
39 | Diminished motivation (HP:0000745) | 2.72433554 |
40 | Epiphyseal dysplasia (HP:0002656) | 2.70116755 |
41 | Pustule (HP:0200039) | 2.68663774 |
42 | Fragile skin (HP:0001030) | 2.63052110 |
43 | Axonal loss (HP:0003447) | 2.62984337 |
44 | Distal lower limb muscle weakness (HP:0009053) | 2.61351222 |
45 | Thick nail (HP:0001805) | 2.60480411 |
46 | Vitreoretinal degeneration (HP:0000655) | 2.48288333 |
47 | Vacuolated lymphocytes (HP:0001922) | 2.46021037 |
48 | Prolonged neonatal jaundice (HP:0006579) | 2.43658462 |
49 | Right ventricular cardiomyopathy (HP:0011663) | 2.43356427 |
50 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.41232877 |
51 | Achilles tendon contracture (HP:0001771) | 2.40862359 |
52 | Peritonitis (HP:0002586) | 2.40219301 |
53 | Spontaneous hematomas (HP:0007420) | 2.39891460 |
54 | Neuronal loss in central nervous system (HP:0002529) | 2.39866170 |
55 | Milia (HP:0001056) | 2.39650229 |
56 | Abnormality of macrophages (HP:0004311) | 2.36425818 |
57 | Metaphyseal irregularity (HP:0003025) | 2.35536561 |
58 | Alopecia of scalp (HP:0002293) | 2.35054196 |
59 | Increased cerebral lipofuscin (HP:0011813) | 2.33364736 |
60 | Pulmonary artery stenosis (HP:0004415) | 2.29363665 |
61 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.28395978 |
62 | Thin bony cortex (HP:0002753) | 2.27790263 |
63 | Progressive neurologic deterioration (HP:0002344) | 2.25864533 |
64 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.24288160 |
65 | Beaking of vertebral bodies (HP:0004568) | 2.23811519 |
66 | Retrobulbar optic neuritis (HP:0100654) | 2.20086186 |
67 | Optic neuritis (HP:0100653) | 2.20086186 |
68 | Hyperparathyroidism (HP:0000843) | 2.19735014 |
69 | Dilatation of the ascending aorta (HP:0005111) | 2.18785092 |
70 | Neonatal short-limb short stature (HP:0008921) | 2.18678114 |
71 | Soft skin (HP:0000977) | 2.16923756 |
72 | Malnutrition (HP:0004395) | 2.16686047 |
73 | Abnormality of the Achilles tendon (HP:0005109) | 2.15054130 |
74 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.13636800 |
75 | Anhidrosis (HP:0000970) | 2.13320928 |
76 | Keratoconjunctivitis sicca (HP:0001097) | 2.12907517 |
77 | Joint stiffness (HP:0001387) | 2.12394784 |
78 | Flat acetabular roof (HP:0003180) | 2.11136701 |
79 | Parakeratosis (HP:0001036) | 2.10781929 |
80 | Bone pain (HP:0002653) | 2.10532165 |
81 | Spinal rigidity (HP:0003306) | 2.08801788 |
82 | Glomerulonephritis (HP:0000099) | 2.08782670 |
83 | Shallow orbits (HP:0000586) | 2.08673859 |
84 | Upper motor neuron abnormality (HP:0002127) | 2.08321228 |
85 | Wormian bones (HP:0002645) | 2.07708623 |
86 | Abnormality of proline metabolism (HP:0010907) | 2.06293453 |
87 | Hydroxyprolinuria (HP:0003080) | 2.06293453 |
88 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.05974805 |
89 | Spondylolisthesis (HP:0003302) | 2.05811786 |
90 | Plantar hyperkeratosis (HP:0007556) | 2.05392615 |
91 | Cellulitis (HP:0100658) | 2.04860001 |
92 | Cupped ribs (HP:0000887) | 2.03927894 |
93 | Broad metatarsal (HP:0001783) | 2.03323188 |
94 | Short hallux (HP:0010109) | 2.02654813 |
95 | Short nail (HP:0001799) | 2.01839389 |
96 | Complement deficiency (HP:0004431) | 2.00867412 |
97 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.00570835 |
98 | Mediastinal lymphadenopathy (HP:0100721) | 1.98741743 |
99 | Nephritis (HP:0000123) | 1.98609308 |
100 | Myocardial infarction (HP:0001658) | 1.98275300 |
101 | Purpura (HP:0000979) | 1.98238065 |
102 | Pathologic fracture (HP:0002756) | 1.96637742 |
103 | Gangrene (HP:0100758) | 1.94804063 |
104 | Supranuclear gaze palsy (HP:0000605) | 1.94715200 |
105 | Gingivitis (HP:0000230) | 1.94092647 |
106 | Fragile nails (HP:0001808) | 1.92992163 |
107 | Abnormality of complement system (HP:0005339) | 1.92043326 |
108 | Asymmetric septal hypertrophy (HP:0001670) | 1.91889981 |
109 | Pulmonary infiltrates (HP:0002113) | 1.91394567 |
110 | J-shaped sella turcica (HP:0002680) | 1.90205046 |
111 | Basal ganglia calcification (HP:0002135) | 1.87701506 |
112 | Abnormality of iron homeostasis (HP:0011031) | 1.87319499 |
113 | Increased connective tissue (HP:0009025) | 1.87303544 |
114 | Nausea (HP:0002018) | 1.84727472 |
115 | Abnormality of the nasal mucosa (HP:0000433) | 1.84707134 |
116 | Dementia (HP:0000726) | 1.84249002 |
117 | Blue sclerae (HP:0000592) | 1.83788835 |
118 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.82918456 |
119 | Keratoconjunctivitis (HP:0001096) | 1.82594145 |
120 | Hepatosplenomegaly (HP:0001433) | 1.81887619 |
121 | Stomach cancer (HP:0012126) | 1.81407756 |
122 | Coxa vara (HP:0002812) | 1.79612862 |
123 | Esophageal varix (HP:0002040) | 1.79558189 |
124 | Platyspondyly (HP:0000926) | 1.78948646 |
125 | Petechiae (HP:0000967) | 1.78514488 |
126 | Hypoplastic ischia (HP:0003175) | 1.77859920 |
127 | Vasculitis (HP:0002633) | 1.77800620 |
128 | Dysostosis multiplex (HP:0000943) | 1.77475145 |
129 | Mitral valve prolapse (HP:0001634) | 1.77346785 |
130 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.74340360 |
131 | Abnormality of the odontoid process (HP:0003310) | 1.74316420 |
132 | Personality changes (HP:0000751) | 1.73677851 |
133 | Abnormality of the nasal septum (HP:0000419) | 1.73170817 |
134 | Ovoid vertebral bodies (HP:0003300) | 1.72655827 |
135 | Inappropriate behavior (HP:0000719) | 1.72111592 |
136 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.71734043 |
137 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.71651173 |
138 | Abnormality of the pericardium (HP:0001697) | 1.71508254 |
139 | Deep venous thrombosis (HP:0002625) | 1.70302706 |
140 | Tetraparesis (HP:0002273) | 1.69308948 |
141 | Polyneuropathy (HP:0001271) | 1.68474364 |
142 | Prostate neoplasm (HP:0100787) | 1.68371890 |
143 | Zonular cataract (HP:0010920) | 1.67383707 |
144 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.66713010 |
145 | Osteoarthritis (HP:0002758) | 1.65896490 |
146 | Persistence of primary teeth (HP:0006335) | 1.64915490 |
147 | Hypoplasia of the odontoid process (HP:0003311) | 1.64448862 |
148 | Aneurysm (HP:0002617) | 1.63443912 |
149 | Polycythemia (HP:0001901) | 1.63059197 |
150 | Thoracolumbar scoliosis (HP:0002944) | 1.63025601 |
151 | Abnormality of the acetabulum (HP:0003170) | 1.62926845 |
152 | Abnormal vertebral ossification (HP:0100569) | 1.62449560 |
153 | Peripheral demyelination (HP:0011096) | 1.62179946 |
154 | Ankle contracture (HP:0006466) | 1.59896202 |
155 | Increased IgM level (HP:0003496) | 1.59625591 |
156 | Upper limb amyotrophy (HP:0009129) | 1.59302116 |
157 | Distal upper limb amyotrophy (HP:0007149) | 1.59302116 |
158 | Cardiomegaly (HP:0001640) | 1.59173964 |
159 | Prolonged bleeding time (HP:0003010) | 1.58990661 |
160 | Follicular hyperkeratosis (HP:0007502) | 1.58655754 |
161 | Mucopolysacchariduria (HP:0008155) | 1.56517595 |
162 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.56517595 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA2 | 4.37496552 |
2 | PIM2 | 3.63826030 |
3 | TGFBR2 | 3.48672983 |
4 | MAP3K3 | 3.33011760 |
5 | MAP3K14 | 2.83687323 |
6 | TIE1 | 2.81779408 |
7 | ERN1 | 2.39028069 |
8 | TBK1 | 2.36298497 |
9 | EPHA3 | 2.24254265 |
10 | EPHB1 | 2.23399383 |
11 | PRPF4B | 1.92950272 |
12 | MST4 | 1.90054801 |
13 | EPHB2 | 1.86358906 |
14 | IKBKB | 1.84583216 |
15 | KDR | 1.66287506 |
16 | IKBKE | 1.60110520 |
17 | MAPK15 | 1.58251920 |
18 | LATS2 | 1.57774000 |
19 | SIK1 | 1.55277793 |
20 | BLK | 1.51852048 |
21 | TRPM7 | 1.51848845 |
22 | PAK4 | 1.48282049 |
23 | STK10 | 1.41070415 |
24 | FER | 1.40479193 |
25 | FGR | 1.40220703 |
26 | CDC42BPA | 1.39257915 |
27 | KIT | 1.38726310 |
28 | NEK9 | 1.35316086 |
29 | MYLK | 1.32432410 |
30 | CHUK | 1.28869786 |
31 | ICK | 1.28401697 |
32 | MAP2K2 | 1.26949160 |
33 | MAP2K3 | 1.26839513 |
34 | NME2 | 1.26597472 |
35 | ARAF | 1.23291589 |
36 | TYK2 | 1.22457725 |
37 | MATK | 1.20752760 |
38 | TTN | 1.20175167 |
39 | IRAK3 | 1.19271700 |
40 | PRKG2 | 1.19168736 |
41 | TESK1 | 1.18910169 |
42 | RIPK1 | 1.17092328 |
43 | LRRK2 | 1.15997424 |
44 | TGFBR1 | 1.15158695 |
45 | MAP3K13 | 1.11887914 |
46 | DDR2 | 1.11603247 |
47 | RPS6KA4 | 1.10738437 |
48 | IRAK2 | 1.09655713 |
49 | BMX | 1.08715392 |
50 | MAP3K11 | 1.08134597 |
51 | MAP3K12 | 1.05363458 |
52 | PIM1 | 1.02095542 |
53 | TEC | 0.96261228 |
54 | CSK | 0.95962956 |
55 | ZAP70 | 0.95436958 |
56 | PTK2 | 0.95345408 |
57 | JAK3 | 0.94127359 |
58 | PTK6 | 0.92261100 |
59 | MAP3K5 | 0.92133434 |
60 | IRAK4 | 0.92011265 |
61 | PBK | 0.90763621 |
62 | RPS6KB2 | 0.86170484 |
63 | JAK1 | 0.86016795 |
64 | SIK3 | 0.84252261 |
65 | PAK2 | 0.83992283 |
66 | TESK2 | 0.83955899 |
67 | FGFR4 | 0.82994480 |
68 | MOS | 0.81443550 |
69 | PTK2B | 0.80454536 |
70 | PDK2 | 0.79728936 |
71 | MAPKAPK3 | 0.79372006 |
72 | IRAK1 | 0.79276736 |
73 | MAPKAPK2 | 0.77913268 |
74 | FLT3 | 0.77684417 |
75 | CDK6 | 0.75172525 |
76 | MAP3K9 | 0.75091722 |
77 | TYRO3 | 0.73777250 |
78 | BTK | 0.73571462 |
79 | ERBB3 | 0.73520939 |
80 | MST1R | 0.71424935 |
81 | NLK | 0.70619119 |
82 | HCK | 0.70446262 |
83 | TAOK1 | 0.68442401 |
84 | BMPR2 | 0.68391654 |
85 | TAOK2 | 0.67874481 |
86 | PDGFRA | 0.67557612 |
87 | GSK3A | 0.67534099 |
88 | GRK7 | 0.66913158 |
89 | MAP3K1 | 0.66516589 |
90 | EIF2AK2 | 0.66326298 |
91 | NUAK1 | 0.66177785 |
92 | ABL2 | 0.65701610 |
93 | ADRBK2 | 0.63725657 |
94 | MET | 0.63434723 |
95 | PIK3CG | 0.62165202 |
96 | PDGFRB | 0.61977690 |
97 | TRIB3 | 0.61081908 |
98 | MAP2K1 | 0.60104587 |
99 | DYRK1B | 0.59171322 |
100 | ABL1 | 0.57048394 |
101 | ERBB4 | 0.55186571 |
102 | DAPK3 | 0.54178784 |
103 | EGFR | 0.52574535 |
104 | STK24 | 0.51511156 |
105 | STK3 | 0.51480854 |
106 | RIPK4 | 0.50821367 |
107 | RPS6KL1 | 0.50316510 |
108 | RPS6KC1 | 0.50316510 |
109 | LIMK1 | 0.49549389 |
110 | ZAK | 0.49343322 |
111 | MAPK4 | 0.48988975 |
112 | JAK2 | 0.47401987 |
113 | CLK1 | 0.46481903 |
114 | FGFR3 | 0.45900395 |
115 | DMPK | 0.45696474 |
116 | ITK | 0.44872640 |
117 | TXK | 0.44722929 |
118 | RPS6KA6 | 0.44274088 |
119 | LYN | 0.42087710 |
120 | CSF1R | 0.41810128 |
121 | MAP3K8 | 0.41104076 |
122 | MAP3K2 | 0.41027948 |
123 | SMG1 | 0.40191765 |
124 | GRK1 | 0.40123336 |
125 | MARK3 | 0.39828871 |
126 | MAP4K1 | 0.39581074 |
127 | HIPK2 | 0.38805470 |
128 | PDPK1 | 0.38626900 |
129 | BRAF | 0.38610369 |
130 | ACVR1B | 0.35870928 |
131 | MAP2K6 | 0.35558651 |
132 | PKN2 | 0.34351586 |
133 | LMTK2 | 0.34009119 |
134 | DYRK3 | 0.33391297 |
135 | RPS6KA2 | 0.32541595 |
136 | PRKD2 | 0.25690224 |
137 | MELK | 0.23744501 |
138 | MTOR | 0.23673082 |
139 | MAP3K6 | 0.22542983 |
140 | PAK1 | 0.20232887 |
141 | RPS6KA1 | 0.19715853 |
142 | MARK2 | 0.19145798 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Malaria_Homo sapiens_hsa05144 | 2.81658737 |
2 | Leishmaniasis_Homo sapiens_hsa05140 | 2.75415366 |
3 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.30919782 |
4 | TNF signaling pathway_Homo sapiens_hsa04668 | 2.25474470 |
5 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.21834502 |
6 | Legionellosis_Homo sapiens_hsa05134 | 2.19337901 |
7 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.03772193 |
8 | Pertussis_Homo sapiens_hsa05133 | 1.98079791 |
9 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.94927474 |
10 | Salmonella infection_Homo sapiens_hsa05132 | 1.85452287 |
11 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.83569409 |
12 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.83550939 |
13 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.83434296 |
14 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.77373012 |
15 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.76240471 |
16 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.74546581 |
17 | Amoebiasis_Homo sapiens_hsa05146 | 1.72080987 |
18 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.71635399 |
19 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.65305881 |
20 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.64662456 |
21 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.57699505 |
22 | Focal adhesion_Homo sapiens_hsa04510 | 1.57494990 |
23 | Shigellosis_Homo sapiens_hsa05131 | 1.52160958 |
24 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.50251780 |
25 | Apoptosis_Homo sapiens_hsa04210 | 1.44265639 |
26 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.44207575 |
27 | Tuberculosis_Homo sapiens_hsa05152 | 1.41046807 |
28 | Phagosome_Homo sapiens_hsa04145 | 1.38592472 |
29 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.36730178 |
30 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.36022012 |
31 | Asthma_Homo sapiens_hsa05310 | 1.35453807 |
32 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.33463324 |
33 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.32002436 |
34 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.29441547 |
35 | Adherens junction_Homo sapiens_hsa04520 | 1.26562477 |
36 | Lysosome_Homo sapiens_hsa04142 | 1.22450097 |
37 | Bladder cancer_Homo sapiens_hsa05219 | 1.21224854 |
38 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.20184518 |
39 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.19970141 |
40 | Measles_Homo sapiens_hsa05162 | 1.19872423 |
41 | Other glycan degradation_Homo sapiens_hsa00511 | 1.17232748 |
42 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.15764173 |
43 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.15208817 |
44 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.14496295 |
45 | Influenza A_Homo sapiens_hsa05164 | 1.14061983 |
46 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.06981111 |
47 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.03846653 |
48 | Platelet activation_Homo sapiens_hsa04611 | 1.03361646 |
49 | Hepatitis B_Homo sapiens_hsa05161 | 1.01506500 |
50 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.00773319 |
51 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 1.00178266 |
52 | Viral myocarditis_Homo sapiens_hsa05416 | 0.97365967 |
53 | Allograft rejection_Homo sapiens_hsa05330 | 0.95520934 |
54 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.95311946 |
55 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.94402396 |
56 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.93134308 |
57 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.92630000 |
58 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.91130836 |
59 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.90015325 |
60 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.89253071 |
61 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.88197728 |
62 | Hepatitis C_Homo sapiens_hsa05160 | 0.87024695 |
63 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.81553046 |
64 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.81503999 |
65 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.81396056 |
66 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.81361633 |
67 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.80782670 |
68 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.79821199 |
69 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.78225373 |
70 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.77744581 |
71 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.76085211 |
72 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.74708328 |
73 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.73361292 |
74 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.72965559 |
75 | Galactose metabolism_Homo sapiens_hsa00052 | 0.72149047 |
76 | Mineral absorption_Homo sapiens_hsa04978 | 0.71300059 |
77 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.71246767 |
78 | HTLV-I infection_Homo sapiens_hsa05166 | 0.71050475 |
79 | Pathways in cancer_Homo sapiens_hsa05200 | 0.70286104 |
80 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.68087813 |
81 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.67713139 |
82 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.65343997 |
83 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.64437013 |
84 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.63648039 |
85 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.63436999 |
86 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.61732674 |
87 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.60402010 |
88 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.60329901 |
89 | Prostate cancer_Homo sapiens_hsa05215 | 0.58965912 |
90 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.58790035 |
91 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.57988604 |
92 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.57329258 |
93 | Melanoma_Homo sapiens_hsa05218 | 0.56205083 |
94 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.55966698 |
95 | Prion diseases_Homo sapiens_hsa05020 | 0.54972803 |
96 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.53852561 |
97 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.52335743 |
98 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.52299929 |
99 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.50170619 |
100 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.50054720 |
101 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.47696132 |
102 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.47485080 |
103 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.46929872 |
104 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.46156072 |
105 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.45793218 |
106 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.44598642 |
107 | Insulin resistance_Homo sapiens_hsa04931 | 0.44580728 |
108 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.44234943 |
109 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.43543123 |
110 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.43052590 |
111 | Endocytosis_Homo sapiens_hsa04144 | 0.42469588 |
112 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.42213787 |
113 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.41738173 |
114 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.38025907 |
115 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.37627357 |
116 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.35205204 |
117 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.33358302 |
118 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.30963073 |
119 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.27937757 |
120 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.24923432 |