IFFO2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1establishment of skin barrier (GO:0061436)7.79676522
2keratinization (GO:0031424)7.70512246
3hemidesmosome assembly (GO:0031581)7.44454460
4regulation of water loss via skin (GO:0033561)7.38828056
5keratinocyte differentiation (GO:0030216)5.73506761
6hair cycle (GO:0042633)5.71704362
7molting cycle (GO:0042303)5.71704362
8skin morphogenesis (GO:0043589)5.42926446
9bundle of His cell to Purkinje myocyte communication (GO:0086069)5.18179221
10multicellular organismal water homeostasis (GO:0050891)4.90336915
11keratinocyte proliferation (GO:0043616)4.87312394
12peptide cross-linking (GO:0018149)4.73885002
13epidermal cell differentiation (GO:0009913)4.53563824
14intermediate filament organization (GO:0045109)4.23173752
15water homeostasis (GO:0030104)4.23079398
16epidermis development (GO:0008544)4.09732881
17surfactant homeostasis (GO:0043129)3.96678414
18ectoderm development (GO:0007398)3.88744408
19long-chain fatty acid biosynthetic process (GO:0042759)3.84088173
20epithelial cell differentiation involved in prostate gland development (GO:0060742)3.82966737
21atrioventricular valve morphogenesis (GO:0003181)3.78447303
22interferon-gamma secretion (GO:0072643)3.68860095
23cell-substrate junction assembly (GO:0007044)3.52480598
24epithelial cell-cell adhesion (GO:0090136)3.41207474
25negative regulation of keratinocyte proliferation (GO:0010839)3.38351844
26regulation of phospholipase A2 activity (GO:0032429)3.34407928
27regulation of ruffle assembly (GO:1900027)3.32366022
28hypotonic response (GO:0006971)3.27474934
29negative regulation of cell fate specification (GO:0009996)3.23055383
30cell adhesion mediated by integrin (GO:0033627)3.22236286
31chemical homeostasis within a tissue (GO:0048875)3.17409440
32planar cell polarity pathway involved in neural tube closure (GO:0090179)3.14229634
33negative regulation of stress fiber assembly (GO:0051497)3.13608727
34regulation of Wnt signaling pathway involved in heart development (GO:0003307)3.04552892
35lipoxygenase pathway (GO:0019372)3.03640636
36fibrinolysis (GO:0042730)3.00702413
37positive regulation of epidermis development (GO:0045684)2.98536372
38positive regulation of epidermal cell differentiation (GO:0045606)2.94885770
39positive regulation of endothelial cell apoptotic process (GO:2000353)2.94243736
40dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.91783215
41regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.89301703
42regulation of keratinocyte differentiation (GO:0045616)2.87137616
43gland morphogenesis (GO:0022612)2.86385329
44gap junction assembly (GO:0016264)2.86347999
45wound healing, spreading of epidermal cells (GO:0035313)2.81498247
46positive regulation of keratinocyte differentiation (GO:0045618)2.77084018
47protein localization to endosome (GO:0036010)2.73147470
48lymph vessel development (GO:0001945)2.72672336
49heart valve morphogenesis (GO:0003179)2.70604378
50cell-substrate adherens junction assembly (GO:0007045)2.69987452
51focal adhesion assembly (GO:0048041)2.69987452
52negative regulation of erythrocyte differentiation (GO:0045647)2.69847990
53intermediate filament cytoskeleton organization (GO:0045104)2.69814897
54keratinocyte development (GO:0003334)2.69476087
55phospholipid scrambling (GO:0017121)2.67078401
56negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.67026717
57response to muramyl dipeptide (GO:0032495)2.66991886
58cytoskeletal anchoring at plasma membrane (GO:0007016)2.65865244
59response to laminar fluid shear stress (GO:0034616)2.64946402
60detection of bacterium (GO:0016045)2.64492408
61regulation of natural killer cell differentiation (GO:0032823)2.63255951
62regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.63075840
63hippo signaling (GO:0035329)2.61761714
64polarized epithelial cell differentiation (GO:0030859)2.61392083
65sphingoid metabolic process (GO:0046519)2.60881612
66linoleic acid metabolic process (GO:0043651)2.60632535
67adherens junction assembly (GO:0034333)2.60208196
68intermediate filament-based process (GO:0045103)2.57659422
69regulation of transforming growth factor beta1 production (GO:0032908)2.56571537
70cellular response to interferon-alpha (GO:0035457)2.55934679
71hair follicle morphogenesis (GO:0031069)2.53098428
72positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.52718738
73regulation of hair follicle development (GO:0051797)2.51233907
74germ cell migration (GO:0008354)2.50221310
75plasma membrane repair (GO:0001778)2.50210837
76wound healing, spreading of cells (GO:0044319)2.49231110
77endodermal cell differentiation (GO:0035987)2.46542551
78negative regulation of fatty acid transport (GO:2000192)2.46088948
79virion attachment to host cell (GO:0019062)2.45884634
80adhesion of symbiont to host cell (GO:0044650)2.45884634
81regulation of cholesterol homeostasis (GO:2000188)2.45763067
82negative regulation of cell fate commitment (GO:0010454)2.45530808
83activation of Rac GTPase activity (GO:0032863)2.44498475
84regulation of cell proliferation involved in kidney development (GO:1901722)2.44177138
85regulation of hypersensitivity (GO:0002883)2.43043403
86collagen fibril organization (GO:0030199)2.41701903
87regulation of glomerular filtration (GO:0003093)2.41437091
88regulation of cardioblast differentiation (GO:0051890)2.40576395
89skin development (GO:0043588)2.40040821
90lateral sprouting from an epithelium (GO:0060601)2.39916676
91detection of other organism (GO:0098543)2.39822201
92cell migration involved in sprouting angiogenesis (GO:0002042)2.37965969
93cellular response to fluid shear stress (GO:0071498)2.37643296
94regulation of epidermis development (GO:0045682)2.37524593
95regulation of chemokine secretion (GO:0090196)2.37478320
96wound healing (GO:0042060)2.37141345
97mesodermal cell differentiation (GO:0048333)2.37110451
98regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.36921267
99glucosamine-containing compound catabolic process (GO:1901072)2.33534050
100sphingosine metabolic process (GO:0006670)2.33202739
101regulation of p38MAPK cascade (GO:1900744)2.31497561
102phosphatidylserine acyl-chain remodeling (GO:0036150)2.31336518
103positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)2.30044512
104stress fiber assembly (GO:0043149)2.28715036
105negative regulation of interferon-gamma production (GO:0032689)2.27592246
106glomerular visceral epithelial cell development (GO:0072015)2.25701790
107cell junction assembly (GO:0034329)2.25694064
108positive regulation of hair follicle development (GO:0051798)2.25658204
109positive regulation of hair cycle (GO:0042635)2.25658204
110regulation of cell fate specification (GO:0042659)2.24978957
111endothelial cell chemotaxis (GO:0035767)2.23891694
112regulation of hair cycle (GO:0042634)2.23563775
113positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.22392202
114neural crest cell development (GO:0014032)2.22286018
115regulation of keratinocyte proliferation (GO:0010837)2.20611243
116negative regulation of catenin import into nucleus (GO:0035414)2.19960619
117epithelium development (GO:0060429)2.19928821
118semaphorin-plexin signaling pathway (GO:0071526)2.19864591
119neuron projection extension involved in neuron projection guidance (GO:1902284)2.19036085
120axon extension involved in axon guidance (GO:0048846)2.19036085
121phosphatidylinositol acyl-chain remodeling (GO:0036149)2.17737182
122growth hormone receptor signaling pathway (GO:0060396)2.17421387
123negative regulation of chondrocyte differentiation (GO:0032331)2.16923810
124cell surface receptor signaling pathway involved in heart development (GO:0061311)2.16677401
125positive regulation of cholesterol efflux (GO:0010875)2.15819240
126positive regulation of hormone metabolic process (GO:0032352)2.15665459
127phospholipid efflux (GO:0033700)2.14679526
128cell junction organization (GO:0034330)2.14573990
129embryonic process involved in female pregnancy (GO:0060136)2.14518848
130cardiac right ventricle morphogenesis (GO:0003215)2.13449296
131positive regulation of p38MAPK cascade (GO:1900745)2.13011320
132regulation of transforming growth factor beta2 production (GO:0032909)2.12861064
133mammary gland epithelial cell proliferation (GO:0033598)2.12088496
134establishment of tissue polarity (GO:0007164)2.11133528
135establishment of planar polarity (GO:0001736)2.11133528
136detection of external biotic stimulus (GO:0098581)2.10683474
137positive regulation of Cdc42 GTPase activity (GO:0043089)2.10371378
138eyelid development in camera-type eye (GO:0061029)2.10037024
139regulation of anoikis (GO:2000209)2.09465315
140cellular component disassembly involved in execution phase of apoptosis (GO:0006921)2.08402761
141negative regulation of anoikis (GO:2000811)2.08214235
142adherens junction organization (GO:0034332)2.07945578
143negative regulation of interleukin-17 production (GO:0032700)2.06365429
144regulation of epidermal cell differentiation (GO:0045604)2.05674318
145response to progesterone (GO:0032570)2.05533726
146endocytic recycling (GO:0032456)2.04384987
147membrane raft organization (GO:0031579)2.04284388
148negative regulation of interleukin-2 production (GO:0032703)2.04253213
149desmosome organization (GO:0002934)11.2513400

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse5.00782121
2TRIM28_21343339_ChIP-Seq_HEK293_Human3.05795133
3* SOX9_24532713_ChIP-Seq_HFSC_Mouse2.49316504
4SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.42965498
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.31764526
6RARG_19884340_ChIP-ChIP_MEFs_Mouse2.19488226
7SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.17723403
8SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.17723403
9P63_26484246_Chip-Seq_KERATINOCYTES_Human2.13445396
10ESR1_21235772_ChIP-Seq_MCF-7_Human2.10976886
11ZNF263_19887448_ChIP-Seq_K562_Human2.10394319
12STAT6_21828071_ChIP-Seq_BEAS2B_Human2.08695383
13FOXO3_23340844_ChIP-Seq_DLD1_Human2.05610356
14TP63_17297297_ChIP-ChIP_HaCaT_Human12.5672105
15ESR2_21235772_ChIP-Seq_MCF-7_Human1.97151812
16ZNF217_24962896_ChIP-Seq_MCF-7_Human1.78449048
17* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.71809973
18CJUN_26792858_Chip-Seq_BT549_Human1.68450206
19CLOCK_20551151_ChIP-Seq_293T_Human1.67934328
20ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.66292664
21TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.51673753
22HIF1A_21447827_ChIP-Seq_MCF-7_Human1.51615575
23ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.49541945
24* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.47010634
25SOX2_20726797_ChIP-Seq_SW620_Human1.44684661
26PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.42588833
27TCF4_18268006_ChIP-ChIP_LS174T_Human1.42251142
28TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.39746346
29RXR_22158963_ChIP-Seq_LIVER_Mouse1.39629778
30VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.39394419
31* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.39338409
32FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.38698119
33PPARA_22158963_ChIP-Seq_LIVER_Mouse1.37359677
34THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.36765932
35STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.35668241
36TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.32559244
37* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.31610557
38LXR_22158963_ChIP-Seq_LIVER_Mouse1.30431642
39PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.29507746
40ATF3_27146783_Chip-Seq_COLON_Human1.28434881
41RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.27787454
42* TP63_23658742_ChIP-Seq_EP156T_Human1.27258201
43RUNX1_27514584_Chip-Seq_MCF-7_Human1.25705756
44EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.25665119
45SMAD_19615063_ChIP-ChIP_OVARY_Human1.23186144
46KLF5_25053715_ChIP-Seq_YYC3_Human1.23014527
47RACK7_27058665_Chip-Seq_MCF-7_Human1.22819109
48CDX2_20551321_ChIP-Seq_CACO-2_Human1.22109028
49AR_21572438_ChIP-Seq_LNCaP_Human1.20778858
50VDR_21846776_ChIP-Seq_THP-1_Human1.20758511
51RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.20340796
52* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.19571838
53MYC_22102868_ChIP-Seq_BL_Human1.19316620
54TP53_18474530_ChIP-ChIP_U2OS_Human1.18694571
55* UBF1/2_26484160_Chip-Seq_HMECs_Human1.18446010
56* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.18105477
57TP53_20018659_ChIP-ChIP_R1E_Mouse1.16332435
58TP53_16413492_ChIP-PET_HCT116_Human1.15962308
59NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.15926707
60* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.14493209
61GATA2_21666600_ChIP-Seq_HMVEC_Human1.14306659
62* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.08307109
63CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.06385950
64EGR1_19374776_ChIP-ChIP_THP-1_Human1.06241778
65ELK3_25401928_ChIP-Seq_HUVEC_Human1.04381488
66* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.03901187
67AHR_22903824_ChIP-Seq_MCF-7_Human1.03740378
68* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.03429391
69VDR_24763502_ChIP-Seq_THP-1_Human1.02560712
70STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.01917872
71JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.01679175
72SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.00885278
73GATA6_25053715_ChIP-Seq_YYC3_Human1.00112961
74* P300_27058665_Chip-Seq_ZR-75-30cells_Human0.99986387
75NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.99510310
76WT1_19549856_ChIP-ChIP_CCG9911_Human0.99076372
77GATA4_25053715_ChIP-Seq_YYC3_Human0.99053782
78NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.98145595
79* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.97148802
80* RXR_22108803_ChIP-Seq_LS180_Human0.96869867
81* KDM2B_26808549_Chip-Seq_K562_Human0.95318101
82* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.94796494
83GATA3_24758297_ChIP-Seq_MCF-7_Human0.94423926
84CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.94359345
85* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.93743949
86SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.93550420
87CTNNB1_20460455_ChIP-Seq_HCT116_Human0.93540388
88ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.93491786
89CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.93413050
90* BRD4_27068464_Chip-Seq_AML-cells_Mouse0.93279702
91SMC4_20622854_ChIP-Seq_HELA_Human0.93197449
92TP53_22127205_ChIP-Seq_IMR90_Human0.92314007
93ZFP281_18757296_ChIP-ChIP_E14_Mouse0.90917865
94TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.90876037
95BRD4_25478319_ChIP-Seq_HGPS_Human0.89828316
96MAF_26560356_Chip-Seq_TH1_Human0.89588689
97NRF2_20460467_ChIP-Seq_MEFs_Mouse0.89379646
98NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.89379646
99WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.88453498
100DNAJC2_21179169_ChIP-ChIP_NT2_Human0.87976034
101STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.86794485
102SOX2_27498859_Chip-Seq_STOMACH_Mouse0.86754989
103* KDM2B_26808549_Chip-Seq_JURKAT_Human0.86576216
104* TP63_22573176_ChIP-Seq_HFKS_Human0.86510082
105BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.86490324
106* SA1_27219007_Chip-Seq_ERYTHROID_Human0.86071263
107* CREB1_26743006_Chip-Seq_LNCaP_Human0.85835746
108RUNX_20019798_ChIP-Seq_JUKART_Human0.85802529
109STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.85045368
110FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.84634427
111TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.83996474
112CDX2_19796622_ChIP-Seq_MESCs_Mouse0.83733823
113EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.83185165
114LXR_22292898_ChIP-Seq_THP-1_Human0.81969007
115* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.81730985
116ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.81451834
117Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.81274994
118SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.80595877
119FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.80392292
120TBX20_22080862_ChIP-Seq_HEART_Mouse0.80160699
121TBX20_22328084_ChIP-Seq_HEART_Mouse0.80160699
122SALL4_18804426_ChIP-ChIP_XEN_Mouse0.79539855
123ARNT_22903824_ChIP-Seq_MCF-7_Human0.79305526
124GATA1_19941826_ChIP-Seq_K562_Human0.78458429
125RUNX1_22412390_ChIP-Seq_EML_Mouse0.77693774
126NFIB_24661679_ChIP-Seq_LUNG_Mouse0.77670907
127ESR1_20079471_ChIP-ChIP_T-47D_Human0.75309010
128* KDM2B_26808549_Chip-Seq_DND41_Human0.75192552
129EGR1_19032775_ChIP-ChIP_M12_Human0.74754141
130TCF7_22412390_ChIP-Seq_EML_Mouse0.74290987
131SMAD3_21741376_ChIP-Seq_HESCs_Human0.72019410
132EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.70966541
133SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.70823915
134EED_16625203_ChIP-ChIP_MESCs_Mouse0.70499673
135FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.70117432

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier6.41168295
2MP0005275_abnormal_skin_tensile5.58056154
3MP0010234_abnormal_vibrissa_follicle5.16332597
4MP0005501_abnormal_skin_physiology3.90666195
5MP0003941_abnormal_skin_development3.85926499
6MP0003705_abnormal_hypodermis_morpholog3.70127513
7MP0002060_abnormal_skin_morphology3.41360080
8MP0000579_abnormal_nail_morphology3.31001420
9MP0001216_abnormal_epidermal_layer2.99699621
10MP0004381_abnormal_hair_follicle2.89198449
11MP0003453_abnormal_keratinocyte_physiol2.78788124
12MP0005409_darkened_coat_color2.67311086
13MP0002254_reproductive_system_inflammat2.66502791
14MP0010678_abnormal_skin_adnexa2.64783914
15MP0002098_abnormal_vibrissa_morphology2.61237657
16MP0003566_abnormal_cell_adhesion2.56484782
17MP0010771_integument_phenotype2.51570142
18MP0000383_abnormal_hair_follicle2.48312146
19MP0000647_abnormal_sebaceous_gland2.39888650
20MP0005451_abnormal_body_composition2.34946626
21MP0004947_skin_inflammation2.34571692
22MP0000377_abnormal_hair_follicle2.22814106
23MP0000467_abnormal_esophagus_morphology2.12706214
24MP0002009_preneoplasia1.87367800
25MP0000762_abnormal_tongue_morphology1.84533586
26MP0008438_abnormal_cutaneous_collagen1.83352505
27MP0000427_abnormal_hair_cycle1.82041591
28MP0010352_gastrointestinal_tract_polyps1.79610633
29MP0009053_abnormal_anal_canal1.72493252
30MP0001346_abnormal_lacrimal_gland1.68001869
31MP0004272_abnormal_basement_membrane1.62291408
32MP0005623_abnormal_meninges_morphology1.60187930
33MP0001243_abnormal_dermal_layer1.52415072
34MP0005076_abnormal_cell_differentiation1.50776587
35MP0009931_abnormal_skin_appearance1.50028057
36MP0001191_abnormal_skin_condition1.49213213
37MP0005023_abnormal_wound_healing1.40986910
38MP0004185_abnormal_adipocyte_glucose1.38725474
39MP0000566_synostosis1.37660932
40MP0003763_abnormal_thymus_physiology1.28711594
41MP0000367_abnormal_coat/_hair1.15756430
42MP0010030_abnormal_orbit_morphology1.15497162
43MP0009384_cardiac_valve_regurgitation1.15014329
44MP0002877_abnormal_melanocyte_morpholog1.10435798
45MP0008260_abnormal_autophagy1.01843299
46MP0001851_eye_inflammation1.00727271
47MP0000537_abnormal_urethra_morphology0.99625145
48MP0003828_pulmonary_edema0.99530910
49MP0001340_abnormal_eyelid_morphology0.99149695
50MP0002166_altered_tumor_susceptibility0.97616582
51MP0005508_abnormal_skeleton_morphology0.97537466
52MP0002282_abnormal_trachea_morphology0.97350236
53MP0009780_abnormal_chondrocyte_physiolo0.96726948
54MP0000627_abnormal_mammary_gland0.95862587
55MP0002234_abnormal_pharynx_morphology0.95789799
56MP0009379_abnormal_foot_pigmentation0.95291155
57MP0003300_gastrointestinal_ulcer0.92342242
58MP0002006_tumorigenesis0.86938840
59MP0001849_ear_inflammation0.86331689
60MP0003950_abnormal_plasma_membrane0.86085725
61MP0005367_renal/urinary_system_phenotyp0.82600684
62MP0000516_abnormal_urinary_system0.82600684
63MP0003091_abnormal_cell_migration0.82129992
64MP0004885_abnormal_endolymph0.81003905
65MP0003045_fibrosis0.80948369
66MP0000015_abnormal_ear_pigmentation0.80735525
67MP0005257_abnormal_intraocular_pressure0.80679021
68MP0002896_abnormal_bone_mineralization0.80552211
69MP0001188_hyperpigmentation0.77464149
70MP0002249_abnormal_larynx_morphology0.77005629
71MP0000685_abnormal_immune_system0.76847305
72MP0003385_abnormal_body_wall0.76763159
73MP0003755_abnormal_palate_morphology0.74598510
74MP0009250_abnormal_appendicular_skeleto0.72785680
75MP0003191_abnormal_cellular_cholesterol0.70857138
76MP0005248_abnormal_Harderian_gland0.69159535
77MP0002095_abnormal_skin_pigmentation0.67837389
78MP0000733_abnormal_muscle_development0.65028313
79MP0009333_abnormal_splenocyte_physiolog0.64439281
80MP0002089_abnormal_postnatal_growth/wei0.64273387
81MP0005503_abnormal_tendon_morphology0.64151492
82MP0005085_abnormal_gallbladder_physiolo0.63989700
83MP0003252_abnormal_bile_duct0.63216019
84MP0001784_abnormal_fluid_regulation0.61731005
85MP0003279_aneurysm0.61671795
86MP0010368_abnormal_lymphatic_system0.60685883
87MP0002233_abnormal_nose_morphology0.60552741
88MP0003329_amyloid_beta_deposits0.59922265
89MP0002177_abnormal_outer_ear0.59268986
90MP0005666_abnormal_adipose_tissue0.57132956
91MP0005390_skeleton_phenotype0.56845501
92MP0000767_abnormal_smooth_muscle0.56801808
93MP0000678_abnormal_parathyroid_gland0.56353460
94MP0005621_abnormal_cell_physiology0.55131221
95MP0002111_abnormal_tail_morphology0.54155712
96MP0003436_decreased_susceptibility_to0.53827098
97MP0001299_abnormal_eye_distance/0.52378893
98MP0000432_abnormal_head_morphology0.51654271
99MP0005388_respiratory_system_phenotype0.51161497
100MP0002133_abnormal_respiratory_system0.51161497
101MP0000858_altered_metastatic_potential0.49976360
102MP0000465_gastrointestinal_hemorrhage0.49489097
103MP0004264_abnormal_extraembryonic_tissu0.48544664
104MP0001533_abnormal_skeleton_physiology0.48249324
105MP0002295_abnormal_pulmonary_circulatio0.48237254
106MP0003448_altered_tumor_morphology0.47992618
107MP0005377_hearing/vestibular/ear_phenot0.47588990
108MP0003878_abnormal_ear_physiology0.47588990
109MP0002697_abnormal_eye_size0.46631721
110MP0006138_congestive_heart_failure0.46487634
111MP0003303_peritoneal_inflammation0.46405970
112MP0001879_abnormal_lymphatic_vessel0.46359717
113MP0001348_abnormal_lacrimal_gland0.46271703
114MP0005375_adipose_tissue_phenotype0.44909083
115MP0002115_abnormal_skeleton_extremities0.44384292
116MP0004782_abnormal_surfactant_physiolog0.44278532
117MP0001958_emphysema0.44194291
118MP0000163_abnormal_cartilage_morphology0.43427917
119MP0001542_abnormal_bone_strength0.43349236
120MP0002998_abnormal_bone_remodeling0.43272237
121MP0001915_intracranial_hemorrhage0.42915697
122MP0005164_abnormal_response_to0.42842008
123MP0008004_abnormal_stomach_pH0.42707495
124MP0004858_abnormal_nervous_system0.42576339
125MP0004019_abnormal_vitamin_homeostasis0.41771855
126MP0005083_abnormal_biliary_tract0.41410674
127MP0005387_immune_system_phenotype0.39989435
128MP0001790_abnormal_immune_system0.39989435
129MP0009840_abnormal_foam_cell0.39660956
130MP0000003_abnormal_adipose_tissue0.39019897

Predicted human phenotypes

RankGene SetZ-score
1Right ventricular cardiomyopathy (HP:0011663)5.90599672
2Increased IgE level (HP:0003212)5.89903312
3Hypotrichosis (HP:0001006)5.89887511
4Plantar hyperkeratosis (HP:0007556)5.27198407
5Abnormality of nail color (HP:0100643)5.07346083
6Fragile nails (HP:0001808)4.91666583
7Woolly hair (HP:0002224)4.88168650
8Onycholysis (HP:0001806)4.87300985
9Palmoplantar hyperkeratosis (HP:0000972)4.60868283
10Milia (HP:0001056)4.49163027
11Palmar hyperkeratosis (HP:0010765)4.32058806
12Atrophic scars (HP:0001075)4.25998514
13Congenital ichthyosiform erythroderma (HP:0007431)4.04665513
14Thick nail (HP:0001805)3.95329540
15Lip pit (HP:0100267)3.83476668
16Abnormality of the axillary hair (HP:0100134)3.74427713
17Abnormality of secondary sexual hair (HP:0009888)3.74427713
18Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.62979317
19Erythroderma (HP:0001019)3.58547129
20Erythema (HP:0010783)3.56149179
21Premature rupture of membranes (HP:0001788)3.55150431
22Alopecia of scalp (HP:0002293)3.48390996
23Advanced eruption of teeth (HP:0006288)3.32479654
24Parakeratosis (HP:0001036)3.32356104
25Abnormal blistering of the skin (HP:0008066)3.30588526
26Pili torti (HP:0003777)3.30032971
27Nail dystrophy (HP:0008404)3.25188858
28Natal tooth (HP:0000695)3.24583783
29Acanthosis nigricans (HP:0000956)3.18595951
30Oral leukoplakia (HP:0002745)3.15444937
31Protrusio acetabuli (HP:0003179)3.15166217
32Abnormality of the salivary glands (HP:0010286)3.12471301
33Fragile skin (HP:0001030)3.00863447
34Distal lower limb muscle weakness (HP:0009053)2.99908974
35Eczematoid dermatitis (HP:0000976)2.92850205
36Hyporeflexia of lower limbs (HP:0002600)2.89594792
37Conjunctival hamartoma (HP:0100780)2.86437308
38Increased connective tissue (HP:0009025)2.76670901
39Peritonitis (HP:0002586)2.75367807
40Shallow orbits (HP:0000586)2.63198477
41Sparse scalp hair (HP:0002209)2.62939106
42Absent eyelashes (HP:0000561)2.60029711
43Selective tooth agenesis (HP:0001592)2.55368151
44Curly hair (HP:0002212)2.54551468
45Corneal erosion (HP:0200020)2.54344534
46Ectropion (HP:0000656)2.48721584
47Ventricular tachycardia (HP:0004756)2.44111569
48Hypohidrosis (HP:0000966)2.38601795
49Oligodontia (HP:0000677)2.33118907
50Sparse eyelashes (HP:0000653)2.31274360
51Ankyloglossia (HP:0010296)2.24087895
52Follicular hyperkeratosis (HP:0007502)2.21684407
53Achilles tendon contracture (HP:0001771)2.21630517
54Abnormality of the gastric mucosa (HP:0004295)2.20238045
55Gangrene (HP:0100758)2.18433572
56Hypoplastic labia majora (HP:0000059)2.17056813
57Abnormality of the Achilles tendon (HP:0005109)2.15811793
58Pustule (HP:0200039)2.14019013
59Abnormal hair laboratory examination (HP:0003328)2.11349674
60Popliteal pterygium (HP:0009756)2.11259695
61Pruritus (HP:0000989)2.09954480
62Xerostomia (HP:0000217)2.08575671
63Pterygium (HP:0001059)2.08519735
64Myocardial infarction (HP:0001658)2.06404100
65Broad face (HP:0000283)2.06304817
66Palmoplantar keratoderma (HP:0000982)2.05687417
67Arterial tortuosity (HP:0005116)2.04233428
68Distal lower limb amyotrophy (HP:0008944)2.02291270
69Abnormality of the distal phalanges of the toes (HP:0010182)2.00369879
70Osteolytic defects of the hand bones (HP:0009699)1.99350894
71Osteolytic defects of the phalanges of the hand (HP:0009771)1.99350894
72Abnormality of the labia majora (HP:0012881)1.97415408
73Concave nail (HP:0001598)1.95846682
74Aplasia cutis congenita (HP:0001057)1.94224197
75Abnormality of oral frenula (HP:0000190)1.93822237
76Blepharitis (HP:0000498)1.93106862
77Obstructive sleep apnea (HP:0002870)1.89850364
78Skin ulcer (HP:0200042)1.89834255
79Xanthomatosis (HP:0000991)1.88829102
80Bronchomalacia (HP:0002780)1.88531930
81Ridged nail (HP:0001807)1.87760561
82Mitral valve prolapse (HP:0001634)1.87140303
83Epidermoid cyst (HP:0200040)1.86723856
84Cerebral aneurysm (HP:0004944)1.84791625
85Hyperhidrosis (HP:0000975)1.83600022
86Short nail (HP:0001799)1.81855058
87Vascular tortuosity (HP:0004948)1.80649668
88Down-sloping shoulders (HP:0200021)1.77221128
89Dilatation of the ascending aorta (HP:0005111)1.76453523
90Scapular winging (HP:0003691)1.75677952
91Deep venous thrombosis (HP:0002625)1.74838173
92Spinal rigidity (HP:0003306)1.74574724
93Hypoplasia of dental enamel (HP:0006297)1.73958352
94Aortic dissection (HP:0002647)1.73892535
95Multifactorial inheritance (HP:0001426)1.73857456
96Aplasia involving bones of the extremities (HP:0009825)1.73278191
97Aplasia involving bones of the upper limbs (HP:0009823)1.73278191
98Aplasia of the phalanges of the hand (HP:0009802)1.73278191
99Hamartoma of the eye (HP:0010568)1.72939013
100Nasolacrimal duct obstruction (HP:0000579)1.72852090
101Brittle hair (HP:0002299)1.68669277
102Fatigable weakness (HP:0003473)1.68293695
103Abnormality of the neuromuscular junction (HP:0003398)1.68293695
104Round ear (HP:0100830)1.67805420
105Neonatal short-limb short stature (HP:0008921)1.65192678
106Laryngomalacia (HP:0001601)1.65086397
107Absent hair (HP:0002298)1.64837883
108Hypergammaglobulinemia (HP:0010702)1.64655564
109Abnormality of hair growth rate (HP:0011363)1.63931233
110Slow-growing hair (HP:0002217)1.63931233
111Anonychia (HP:0001798)1.63240314
112Neurofibrillary tangles (HP:0002185)1.63055407
113Broad metatarsal (HP:0001783)1.62860306
114Split foot (HP:0001839)1.62210993
115Hypoplasia of the iris (HP:0007676)1.61657677
116Coronal craniosynostosis (HP:0004440)1.60661088
117Conical tooth (HP:0000698)1.60421408
118Carious teeth (HP:0000670)1.60134137
119Melanocytic nevus (HP:0000995)1.59635195
120Lack of skin elasticity (HP:0100679)1.58697023
121Abnormality of the dental root (HP:0006486)1.58622599
122Taurodontia (HP:0000679)1.58622599
123Abnormality of permanent molar morphology (HP:0011071)1.58622599
124Corneal dystrophy (HP:0001131)1.58586251
125Soft skin (HP:0000977)1.58059531
126Thin bony cortex (HP:0002753)1.56788198
127Coarse hair (HP:0002208)1.55921852
128Aortic aneurysm (HP:0004942)1.55395746
129Ankle contracture (HP:0006466)1.54639803
130Tibial bowing (HP:0002982)1.54122622
131Neonatal death (HP:0003811)1.53897728
132Abnormality of molar (HP:0011077)1.52762831
133Abnormality of molar morphology (HP:0011070)1.52762831
134Dehydration (HP:0001944)1.51554221
135Vertebral arch anomaly (HP:0008438)1.49546604
136Abnormality of the fingernails (HP:0001231)1.44864718
137Autoamputation (HP:0001218)1.44838060

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPKAPK33.37400591
2LATS13.27585308
3PRPF4B3.21934651
4FER3.21108594
5MST43.18005384
6MAP3K33.15159822
7EPHA22.86527047
8MST1R2.86184978
9TRIB32.77723913
10EPHB22.74742664
11EPHA32.39592683
12MAP3K62.09764684
13FGFR42.03796830
14ERN12.03680360
15PTK61.99210557
16SMG11.92072051
17SIK11.86208725
18RPS6KB21.80942480
19TTN1.75989424
20RIPK11.72657239
21EPHB11.70935324
22LATS21.69618946
23LRRK21.69371958
24PIM21.66883300
25NTRK11.62947189
26TRPM71.59718026
27ICK1.58835282
28EEF2K1.54422153
29MAP3K21.53593697
30FGFR31.50295907
31TAOK11.48525348
32MAP3K131.48426627
33STK101.46774208
34DMPK1.43025400
35PDGFRA1.42687072
36PTK21.41570176
37DDR21.36736802
38CDK61.28748904
39PKN21.24251395
40FGFR21.18209567
41MET1.17861846
42PRKD21.14869557
43LMTK21.11605972
44FGFR11.11397551
45TGFBR21.09017839
46MAP3K141.06944615
47RPS6KA41.05258997
48BMX1.03572168
49KSR21.02583603
50MAP3K91.01720990
51FRK0.99234232
52DYRK1B0.98114409
53PAK20.97649725
54NEK90.97286826
55PAK30.96950744
56MAP2K30.95856939
57MAP3K70.92997635
58TYK20.92380662
59BRD40.91567846
60ARAF0.90539965
61MAPK70.90104562
62JAK10.88911099
63ERBB30.88310089
64CDC42BPA0.88096782
65SGK30.87582866
66BMPR20.86499463
67STK30.85336867
68SIK30.80138119
69MAP3K10.79573551
70PDGFRB0.79067658
71RPS6KA20.78122296
72MAPK120.75966983
73IKBKB0.74149102
74CSK0.72985741
75ZAP700.72513361
76CHUK0.70605475
77GSK3A0.68719530
78WNK10.67039981
79PIK3CG0.66740998
80MTOR0.66439000
81MAPKAPK20.66251796
82SGK4940.65706599
83SGK2230.65706599
84IRAK10.64687051
85ROCK10.63681436
86MAP2K20.63603989
87TBK10.63324939
88PRKD10.63174517
89MAP2K10.62987316
90MAP3K110.62038146
91MAP3K50.61855381
92MAP4K10.60787562
93GRK10.60303235
94MAPK150.59729752
95RET0.56190820
96JAK30.53998412
97MAPKAPK50.51169605
98CDK120.50965996
99NUAK10.50635657
100ROCK20.50631082
101IRAK20.50613781
102STK380.48690398
103ITK0.47936861
104RPS6KA10.47515651
105NLK0.46849623
106TGFBR10.46623897
107ERBB20.45823499
108ERBB40.45026914
109PDPK10.44907287
110PAK40.44581532
111MELK0.44489633
112GRK60.43991126
113SGK20.43722646
114TYRO30.43526791
115BCR0.40330498
116IRAK40.39579823
117CDK90.38933434
118HCK0.38863120
119ABL10.37256117
120STK110.36619527
121RPS6KC10.36174963
122RPS6KL10.36174963
123STK240.35063510
124PRKAA20.33219754
125MOS0.33180300
126MARK20.32912244
127HIPK20.32811167
128CAMK1D0.32478797
129EGFR0.31808147
130ALK0.31382630
131SRC0.31346435
132ILK0.31033983
133IRAK30.30578712
134TAOK20.30067039

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.34576263
2Adherens junction_Homo sapiens_hsa045201.89852986
3Proteoglycans in cancer_Homo sapiens_hsa052051.81978079
4Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.73390351
5Amoebiasis_Homo sapiens_hsa051461.65648600
6Small cell lung cancer_Homo sapiens_hsa052221.64696835
7Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.56730562
8Hippo signaling pathway_Homo sapiens_hsa043901.54206224
9Bladder cancer_Homo sapiens_hsa052191.53443567
10Focal adhesion_Homo sapiens_hsa045101.53276150
11Nitrogen metabolism_Homo sapiens_hsa009101.48424872
12Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.48292430
13Complement and coagulation cascades_Homo sapiens_hsa046101.46304426
14Basal cell carcinoma_Homo sapiens_hsa052171.46127781
15Staphylococcus aureus infection_Homo sapiens_hsa051501.43945587
16Phenylalanine metabolism_Homo sapiens_hsa003601.42219168
17MicroRNAs in cancer_Homo sapiens_hsa052061.38511919
18Phosphatidylinositol signaling system_Homo sapiens_hsa040701.37149861
19Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.36265013
20AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.34973630
21Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.33838653
22Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.31578823
23TGF-beta signaling pathway_Homo sapiens_hsa043501.31317415
24Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.30391338
25Toxoplasmosis_Homo sapiens_hsa051451.27838218
26Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.25912714
27Primary bile acid biosynthesis_Homo sapiens_hsa001201.25362722
28Leukocyte transendothelial migration_Homo sapiens_hsa046701.25026954
29Non-small cell lung cancer_Homo sapiens_hsa052231.23121574
30TNF signaling pathway_Homo sapiens_hsa046681.22023903
31Choline metabolism in cancer_Homo sapiens_hsa052311.20622693
32Chemical carcinogenesis_Homo sapiens_hsa052041.20520948
33Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.19640897
34Axon guidance_Homo sapiens_hsa043601.19109789
35Tight junction_Homo sapiens_hsa045301.16762706
36p53 signaling pathway_Homo sapiens_hsa041151.15891828
37Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.14901874
38Retinol metabolism_Homo sapiens_hsa008301.14333130
39VEGF signaling pathway_Homo sapiens_hsa043701.12532193
40Phospholipase D signaling pathway_Homo sapiens_hsa040721.09948672
41Inositol phosphate metabolism_Homo sapiens_hsa005621.08758621
42Cyanoamino acid metabolism_Homo sapiens_hsa004601.08593961
43Histidine metabolism_Homo sapiens_hsa003401.05608014
44Caffeine metabolism_Homo sapiens_hsa002321.04784718
45Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.03699289
46Thyroid hormone signaling pathway_Homo sapiens_hsa049191.02710527
47B cell receptor signaling pathway_Homo sapiens_hsa046621.01508727
48GnRH signaling pathway_Homo sapiens_hsa049121.01414374
49T cell receptor signaling pathway_Homo sapiens_hsa046601.01052746
50Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.98974663
51Protein digestion and absorption_Homo sapiens_hsa049740.97978060
52Hedgehog signaling pathway_Homo sapiens_hsa043400.96180847
53Circadian rhythm_Homo sapiens_hsa047100.95421460
54Chronic myeloid leukemia_Homo sapiens_hsa052200.94856623
55Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.94812222
56Central carbon metabolism in cancer_Homo sapiens_hsa052300.94214988
57Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.94024130
58Glioma_Homo sapiens_hsa052140.93990104
59Long-term potentiation_Homo sapiens_hsa047200.93944192
60Jak-STAT signaling pathway_Homo sapiens_hsa046300.93037080
61Endocytosis_Homo sapiens_hsa041440.90819598
62Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.90550304
63Hepatitis C_Homo sapiens_hsa051600.90041221
64Acute myeloid leukemia_Homo sapiens_hsa052210.89461644
65Sphingolipid metabolism_Homo sapiens_hsa006000.87165463
66Influenza A_Homo sapiens_hsa051640.85873919
67Pancreatic cancer_Homo sapiens_hsa052120.85135181
68Regulation of actin cytoskeleton_Homo sapiens_hsa048100.84938145
69Platelet activation_Homo sapiens_hsa046110.84764724
70Insulin resistance_Homo sapiens_hsa049310.84567440
71Shigellosis_Homo sapiens_hsa051310.83896507
72Linoleic acid metabolism_Homo sapiens_hsa005910.83883837
73Rap1 signaling pathway_Homo sapiens_hsa040150.83882974
74Toll-like receptor signaling pathway_Homo sapiens_hsa046200.83381058
75Melanogenesis_Homo sapiens_hsa049160.83012455
76Apoptosis_Homo sapiens_hsa042100.82759774
77Insulin signaling pathway_Homo sapiens_hsa049100.82448221
78Osteoclast differentiation_Homo sapiens_hsa043800.82372121
79Long-term depression_Homo sapiens_hsa047300.82202593
80Arginine biosynthesis_Homo sapiens_hsa002200.82198035
81PPAR signaling pathway_Homo sapiens_hsa033200.81366693
82alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.81083299
83Pertussis_Homo sapiens_hsa051330.80834913
84MAPK signaling pathway_Homo sapiens_hsa040100.79806191
85Adipocytokine signaling pathway_Homo sapiens_hsa049200.78820613
86mTOR signaling pathway_Homo sapiens_hsa041500.78704210
87Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.78224601
88Colorectal cancer_Homo sapiens_hsa052100.77938453
89Endometrial cancer_Homo sapiens_hsa052130.76397203
90Malaria_Homo sapiens_hsa051440.76232933
91Estrogen signaling pathway_Homo sapiens_hsa049150.76024277
92Hepatitis B_Homo sapiens_hsa051610.75757924
93Vascular smooth muscle contraction_Homo sapiens_hsa042700.74480568
94Prion diseases_Homo sapiens_hsa050200.74107498
95Ether lipid metabolism_Homo sapiens_hsa005650.73464293
96Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.73398325
97Prostate cancer_Homo sapiens_hsa052150.72779442
98Wnt signaling pathway_Homo sapiens_hsa043100.72090962
99Measles_Homo sapiens_hsa051620.71839793
100Tyrosine metabolism_Homo sapiens_hsa003500.71685901
101FoxO signaling pathway_Homo sapiens_hsa040680.71563159
102Melanoma_Homo sapiens_hsa052180.70982401
103Dilated cardiomyopathy_Homo sapiens_hsa054140.70715620
104Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.70060013
105Pathways in cancer_Homo sapiens_hsa052000.69130773
106Prolactin signaling pathway_Homo sapiens_hsa049170.67722020
107Dorso-ventral axis formation_Homo sapiens_hsa043200.66884884
108Notch signaling pathway_Homo sapiens_hsa043300.66115564
109NOD-like receptor signaling pathway_Homo sapiens_hsa046210.66090021
110Fat digestion and absorption_Homo sapiens_hsa049750.65991789
111PI3K-Akt signaling pathway_Homo sapiens_hsa041510.65525647
112Other glycan degradation_Homo sapiens_hsa005110.65019454
113Bile secretion_Homo sapiens_hsa049760.64997464
114RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.64949240
115Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64907669
116NF-kappa B signaling pathway_Homo sapiens_hsa040640.64800312
117Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.64077913
118Steroid hormone biosynthesis_Homo sapiens_hsa001400.63855231
119Ras signaling pathway_Homo sapiens_hsa040140.63187395
120ErbB signaling pathway_Homo sapiens_hsa040120.62622720
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.61789031
122Glycerophospholipid metabolism_Homo sapiens_hsa005640.60998216
123Ovarian steroidogenesis_Homo sapiens_hsa049130.60710861
124Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.60591190
125Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60537153
126Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.58693287
127Viral myocarditis_Homo sapiens_hsa054160.58093892
128Leishmaniasis_Homo sapiens_hsa051400.57924690
129Fatty acid biosynthesis_Homo sapiens_hsa000610.56707276
130Renin secretion_Homo sapiens_hsa049240.56619493
131Arachidonic acid metabolism_Homo sapiens_hsa005900.55599066
132Neurotrophin signaling pathway_Homo sapiens_hsa047220.54715408
133Thyroid cancer_Homo sapiens_hsa052160.51350488
134Salmonella infection_Homo sapiens_hsa051320.51097278
135HTLV-I infection_Homo sapiens_hsa051660.50912234
136Tuberculosis_Homo sapiens_hsa051520.50012280
137ABC transporters_Homo sapiens_hsa020100.49696324
138Renal cell carcinoma_Homo sapiens_hsa052110.49407660

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