IFI27

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to interferon-beta (GO:0035456)5.97906803
2eosinophil chemotaxis (GO:0048245)5.20963566
3response to interferon-alpha (GO:0035455)5.13421501
4* cellular response to type I interferon (GO:0071357)5.00414266
5* type I interferon signaling pathway (GO:0060337)5.00414266
6* response to type I interferon (GO:0034340)4.94594227
7regulation of sequestering of triglyceride (GO:0010889)4.74553926
8eosinophil migration (GO:0072677)4.60420599
9valine metabolic process (GO:0006573)4.58998313
10complement activation, classical pathway (GO:0006958)4.25600507
11fatty acid beta-oxidation (GO:0006635)4.17575413
12positive regulation of pseudopodium assembly (GO:0031274)3.98093043
13low-density lipoprotein particle clearance (GO:0034383)3.92575883
14negative regulation of viral genome replication (GO:0045071)3.91214710
15fatty acid catabolic process (GO:0009062)3.89223304
16brown fat cell differentiation (GO:0050873)3.87094035
17fatty acid oxidation (GO:0019395)3.80224242
18triglyceride catabolic process (GO:0019433)3.79270521
19complement activation (GO:0006956)3.77484540
20negative regulation of viral entry into host cell (GO:0046597)3.76261912
21lipid oxidation (GO:0034440)3.74682964
22biotin metabolic process (GO:0006768)3.74356417
23alpha-linolenic acid metabolic process (GO:0036109)3.72465929
24positive regulation of respiratory burst (GO:0060267)3.69381323
25fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.66778906
26antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.62483410
27antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.62483410
28fatty acid transmembrane transport (GO:1902001)3.58390324
29fibrinolysis (GO:0042730)3.57984257
30regulation of pseudopodium assembly (GO:0031272)3.53063286
31positive regulation of fatty acid oxidation (GO:0046321)3.49546430
32branched-chain amino acid catabolic process (GO:0009083)3.43766717
33acylglycerol catabolic process (GO:0046464)3.41508728
34neutral lipid catabolic process (GO:0046461)3.41508728
35antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.39916528
36carnitine shuttle (GO:0006853)3.39480893
37negative regulation of macrophage derived foam cell differentiation (GO:0010745)3.36000660
38interferon-gamma-mediated signaling pathway (GO:0060333)3.35312480
39positive regulation of triglyceride lipase activity (GO:0061365)3.33453327
40positive regulation of lipoprotein lipase activity (GO:0051006)3.33453327
41cellular response to interferon-alpha (GO:0035457)3.32919345
42immunoglobulin mediated immune response (GO:0016064)3.32445621
43regulation of cellular extravasation (GO:0002691)3.31776226
44branched-chain amino acid metabolic process (GO:0009081)3.30136946
45regulation of triglyceride catabolic process (GO:0010896)3.30125692
46positive regulation of fatty acid beta-oxidation (GO:0032000)3.27945357
47morphogenesis of an endothelium (GO:0003159)3.27457709
48endothelial tube morphogenesis (GO:0061154)3.27457709
49monocarboxylic acid catabolic process (GO:0072329)3.26952302
50negative regulation of complement activation (GO:0045916)3.24653555
51fatty-acyl-CoA metabolic process (GO:0035337)3.23955735
52regulation of fatty acid oxidation (GO:0046320)3.23545411
53regulation of viral entry into host cell (GO:0046596)3.23304648
54interferon-gamma secretion (GO:0072643)3.20909696
55cellular response to interferon-beta (GO:0035458)3.20024839
56protein activation cascade (GO:0072376)3.17488366
57antigen processing and presentation of endogenous antigen (GO:0019883)3.13859052
58regulation of mononuclear cell migration (GO:0071675)3.12511000
59acyl-CoA biosynthetic process (GO:0071616)3.11741503
60thioester biosynthetic process (GO:0035384)3.11741503
61fatty-acyl-CoA biosynthetic process (GO:0046949)3.11173394
62regulation of respiratory burst (GO:0060263)3.06175149
63phenol-containing compound catabolic process (GO:0019336)3.05067854
64detection of bacterium (GO:0016045)3.04677797
65extracellular fibril organization (GO:0043206)3.03926736
66L-phenylalanine catabolic process (GO:0006559)3.03816518
67erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.03816518
68cellular response to exogenous dsRNA (GO:0071360)3.03177387
69fibril organization (GO:0097435)3.03105092
70negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.02090064
71regulation of cholesterol storage (GO:0010885)2.99702841
72regulation of protein activation cascade (GO:2000257)2.99260252
73erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.98931500
74L-phenylalanine metabolic process (GO:0006558)2.98931500
75lipid storage (GO:0019915)2.98477388
76adhesion of symbiont to host cell (GO:0044650)2.94837369
77virion attachment to host cell (GO:0019062)2.94837369
78protein maturation by protein folding (GO:0022417)2.94707546
79long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.93697701
80hormone catabolic process (GO:0042447)2.92824234
81triglyceride biosynthetic process (GO:0019432)2.91278280
82long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.90849488
83negative regulation of protein activation cascade (GO:2000258)2.89829288
84sulfur amino acid catabolic process (GO:0000098)2.89296203
85regulation of macrophage chemotaxis (GO:0010758)2.89149564
86positive regulation of Cdc42 GTPase activity (GO:0043089)2.89055642
87neutral lipid biosynthetic process (GO:0046460)2.88826847
88acylglycerol biosynthetic process (GO:0046463)2.88826847
89regulation of cholesterol metabolic process (GO:0090181)2.87992475
90negative regulation of protein autophosphorylation (GO:0031953)2.87402453
91negative regulation of glycoprotein metabolic process (GO:1903019)2.87205550
92detection of other organism (GO:0098543)2.85886260
93regulation of metalloenzyme activity (GO:0048552)2.85771081
94response to interferon-gamma (GO:0034341)2.85563711
95complement activation, alternative pathway (GO:0006957)2.84730623
96short-chain fatty acid metabolic process (GO:0046459)2.82356904
97urea cycle (GO:0000050)2.82016071
98GDP-mannose metabolic process (GO:0019673)2.81785408
99positive regulation of lipid catabolic process (GO:0050996)2.81512793
100urea metabolic process (GO:0019627)2.80329262
101angiotensin maturation (GO:0002003)2.79877270
102NADH metabolic process (GO:0006734)2.78646621
103acetyl-CoA metabolic process (GO:0006084)2.78058486
104transcytosis (GO:0045056)2.77875706
105plasma lipoprotein particle clearance (GO:0034381)2.77518885
106negative regulation of humoral immune response (GO:0002921)2.76700797
107carnitine transmembrane transport (GO:1902603)2.76526966
108carnitine metabolic process (GO:0009437)2.76469550
109nucleoside diphosphate biosynthetic process (GO:0009133)2.74109228
110triglyceride metabolic process (GO:0006641)2.73333715
111lipid particle organization (GO:0034389)2.73284415
112thioester metabolic process (GO:0035383)2.71760187
113acyl-CoA metabolic process (GO:0006637)2.71760187
114positive regulation of fatty acid metabolic process (GO:0045923)2.69854542
115epoxygenase P450 pathway (GO:0019373)2.69539973
116negative regulation of lipid storage (GO:0010888)2.69151270
117white fat cell differentiation (GO:0050872)2.69039211
118barbed-end actin filament capping (GO:0051016)2.68207086
119positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.68106428
120positive regulation of triglyceride metabolic process (GO:0090208)2.67199898
121cellular response to interferon-gamma (GO:0071346)2.66493534
122regulation of triglyceride metabolic process (GO:0090207)2.66457148
123opsonization (GO:0008228)2.65680461
124negative regulation of viral process (GO:0048525)2.63856753
125nitrogen cycle metabolic process (GO:0071941)2.63053486
126negative regulation of lipase activity (GO:0060192)2.61951222
127arginine catabolic process (GO:0006527)2.61916555
128cellular response to virus (GO:0098586)2.61865611
129glomerular filtration (GO:0003094)2.60678125
130negative regulation of coagulation (GO:0050819)2.59785797
131regulation of dendritic cell antigen processing and presentation (GO:0002604)2.59515425
132regulation of fatty acid beta-oxidation (GO:0031998)2.59418768
133positive regulation of type 2 immune response (GO:0002830)2.59118001
134negative regulation of hemostasis (GO:1900047)2.58729208
135negative regulation of blood coagulation (GO:0030195)2.58729208
136defense response to virus (GO:0051607)2.58402829
137positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.57903184
138detection of external biotic stimulus (GO:0098581)2.57616885
139adhesion of symbiont to host (GO:0044406)2.56666105
140acylglycerol metabolic process (GO:0006639)2.56483330
141regulation of triglyceride biosynthetic process (GO:0010866)2.56463413
142arginine metabolic process (GO:0006525)2.56115990
143neutral lipid metabolic process (GO:0006638)2.55039630
144regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.54636848
145protein carboxylation (GO:0018214)2.53726294
146peptidyl-glutamic acid carboxylation (GO:0017187)2.53726294
147renal filtration (GO:0097205)2.53566759
148bile acid biosynthetic process (GO:0006699)2.53400809
149triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.53234513
150carnitine transport (GO:0015879)2.52124583
151amino-acid betaine transport (GO:0015838)2.52124583
152amino-acid betaine metabolic process (GO:0006577)2.51398318
153negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.50618878
154cellular lipid catabolic process (GO:0044242)2.50127978
155antimicrobial humoral response (GO:0019730)2.49602888
156coenzyme A metabolic process (GO:0015936)2.48562270
157drug metabolic process (GO:0017144)2.48478330
158bile acid and bile salt transport (GO:0015721)2.48261776
159lymphocyte chemotaxis (GO:0048247)2.47408110
160NADP metabolic process (GO:0006739)2.46895073
161tricarboxylic acid metabolic process (GO:0072350)2.45412532
162positive regulation of cholesterol transport (GO:0032376)2.45340563
163positive regulation of sterol transport (GO:0032373)2.45340563
164positive regulation of toll-like receptor signaling pathway (GO:0034123)2.45206652
165NADPH regeneration (GO:0006740)2.44500701
166regulation of RIG-I signaling pathway (GO:0039535)2.44339226
167xenobiotic catabolic process (GO:0042178)2.43884833
168peptide catabolic process (GO:0043171)2.43866654
169coenzyme catabolic process (GO:0009109)2.42025140
170succinate metabolic process (GO:0006105)2.41998164
171ethanol oxidation (GO:0006069)2.41384751
172cofactor catabolic process (GO:0051187)2.41203197
173cellular copper ion homeostasis (GO:0006878)2.40555058
174humoral immune response (GO:0006959)2.39892615
175regulation of viral genome replication (GO:0045069)2.39435679
176coenzyme A biosynthetic process (GO:0015937)2.38616619
177fructose metabolic process (GO:0006000)2.38061868
178antibacterial humoral response (GO:0019731)2.37909677
179bile acid metabolic process (GO:0008206)2.36754171
180glucuronate metabolic process (GO:0019585)2.35945605
181uronic acid metabolic process (GO:0006063)2.35945605
182L-ascorbic acid metabolic process (GO:0019852)2.35191850
183triglyceride homeostasis (GO:0070328)2.34026592
184acylglycerol homeostasis (GO:0055090)2.34026592
185regulation of cholesterol biosynthetic process (GO:0045540)2.33861128
186membrane raft organization (GO:0031579)2.33688074
187regulation of macrophage derived foam cell differentiation (GO:0010743)2.32936475
188positive regulation of cholesterol efflux (GO:0010875)2.31558534
189regulation of complement activation (GO:0030449)2.29437719
190organic acid catabolic process (GO:0016054)2.27261812

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse8.55837841
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.16192167
3TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.90800815
4RXR_22158963_ChIP-Seq_LIVER_Mouse3.70782518
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.69191963
6PPARA_22158963_ChIP-Seq_LIVER_Mouse3.17050510
7LXR_22158963_ChIP-Seq_LIVER_Mouse2.84173826
8TP63_17297297_ChIP-ChIP_HaCaT_Human2.75130008
9IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.70633535
10CLOCK_20551151_ChIP-Seq_293T_Human2.69108011
11RARG_19884340_ChIP-ChIP_MEFs_Mouse2.58714102
12EGR1_23403033_ChIP-Seq_LIVER_Mouse2.56441555
13TRIM28_21343339_ChIP-Seq_HEK293_Human2.42058636
14FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.39263027
15TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.38111214
16CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.28049864
17CDX2_20551321_ChIP-Seq_CACO-2_Human2.20545214
18PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.14506841
19STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.14090200
20SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.02076081
21IRF8_21731497_ChIP-ChIP_J774_Mouse1.99755607
22IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.93274952
23TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.92910605
24NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.90167942
25FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.83220532
26BP1_19119308_ChIP-ChIP_Hs578T_Human1.80235098
27CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.75464525
28GATA1_22025678_ChIP-Seq_K562_Human1.69718014
29MYB_21317192_ChIP-Seq_ERMYB_Mouse1.66445174
30THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.65822784
31SRY_22984422_ChIP-ChIP_TESTIS_Rat1.65284648
32RACK7_27058665_Chip-Seq_MCF-7_Human1.60676722
33RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.58354437
34CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.57032679
35STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.54676407
36RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.51060345
37SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.49914573
38NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.48694822
39SOX2_27498859_Chip-Seq_STOMACH_Mouse1.48592972
40MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.48237386
41LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.47765737
42RUNX_20019798_ChIP-Seq_JUKART_Human1.47509473
43GATA2_21666600_ChIP-Seq_HMVEC_Human1.47243386
44Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.45904503
45TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.45345598
46NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.43563294
47* SOX2_20726797_ChIP-Seq_SW620_Human1.41157052
48STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.34773669
49GATA4_25053715_ChIP-Seq_YYC3_Human1.34016141
50BCOR_27268052_Chip-Seq_Bcells_Human1.34001431
51FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.33145023
52BCL6_27268052_Chip-Seq_Bcells_Human1.33034262
53NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.32816206
54* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.32357014
55IRF8_27001747_Chip-Seq_BMDM_Mouse1.32171080
56CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.30152571
57CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.25584893
58ESR2_21235772_ChIP-Seq_MCF-7_Human1.25309941
59NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.23241541
60NRF2_20460467_ChIP-Seq_MEFs_Mouse1.23241541
61STAT1_20625510_ChIP-Seq_HELA_Human1.23098068
62P63_26484246_Chip-Seq_KERATINOCYTES_Human1.22030810
63GATA6_25053715_ChIP-Seq_YYC3_Human1.21705715
64HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.19168101
65KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.17438653
66ZNF263_19887448_ChIP-Seq_K562_Human1.16412521
67* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.15025410
68SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.13956052
69SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.13956052
70JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.13815807
71PPAR_26484153_Chip-Seq_NCI-H1993_Human1.13334244
72MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.11588747
73* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.11215009
74PPARG_20887899_ChIP-Seq_3T3-L1_Mouse1.10693968
75PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.08941154
76CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.08607809
77EGR1_19032775_ChIP-ChIP_M12_Human1.08121391
78PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.07165807
79SCL_19346495_ChIP-Seq_HPC-7_Human1.06747519
80KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.06610816
81CJUN_26792858_Chip-Seq_BT549_Human1.05619523
82CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.02642784
83TET1_21451524_ChIP-Seq_MESCs_Mouse1.01155061
84CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.00981842
85* SA1_27219007_Chip-Seq_Bcells_Human1.00933863
86ESR1_21235772_ChIP-Seq_MCF-7_Human1.00688889
87PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.00669128
88* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99570637
89ATF3_27146783_Chip-Seq_COLON_Human0.99149385
90ESR1_20079471_ChIP-ChIP_T-47D_Human0.98595729
91UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.96849736
92ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.96833840
93SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.96784592
94CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95817602
95SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.95681443
96FOXO3_23340844_ChIP-Seq_DLD1_Human0.95023418
97ELF1_20517297_ChIP-Seq_JURKAT_Human0.94844032
98SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.94114261
99SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93023092
100ELK3_25401928_ChIP-Seq_HUVEC_Human0.92399073
101CSB_26484114_Chip-Seq_FIBROBLAST_Human0.89735357
102FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.89626931
103TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.89592390
104SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.89284066
105CTCF_20526341_ChIP-Seq_ESCs_Human0.88951227
106P300_27268052_Chip-Seq_Bcells_Human0.88581721
107BRD4_27068464_Chip-Seq_AML-cells_Mouse0.88460506
108TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.88325320
109TP63_22573176_ChIP-Seq_HFKS_Human0.88110717
110FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.87898091
111* VDR_24763502_ChIP-Seq_THP-1_Human0.87823540
112GATA3_24758297_ChIP-Seq_MCF-7_Human0.87741831
113CDX2_19796622_ChIP-Seq_MESCs_Mouse0.87315520
114ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.87021740
115GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.85618580
116PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.85082614
117STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.84553493
118LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.84454486
119TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.84109157
120BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.83922825
121BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.83272555
122GATA2_19941826_ChIP-Seq_K562_Human0.82795547
123FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.82468013
124ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.81711431
125LXR_22292898_ChIP-Seq_THP-1_Human0.79215602
126MYB_26560356_Chip-Seq_TH2_Human0.79189223
127MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.78758375
128SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.78755028
129HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.77086669
130RAD21_21589869_ChIP-Seq_MESCs_Mouse0.76828345
131CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.76547723
132SOX9_24532713_ChIP-Seq_HFSC_Mouse0.76145588
133MAF_26560356_Chip-Seq_TH1_Human0.75667400
134HIF1A_21447827_ChIP-Seq_MCF-7_Human0.74867617
135GATA1_22383799_ChIP-Seq_G1ME_Mouse0.73626942
136SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.73034231
137PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.72805872
138RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.72564784
139* VDR_24787735_ChIP-Seq_THP-1_Human0.71472586

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen3.64240416
2MP0005670_abnormal_white_adipose3.61771422
3MP0003724_increased_susceptibility_to3.09339810
4MP0005365_abnormal_bile_salt2.66241922
5MP0002138_abnormal_hepatobiliary_system2.61145443
6MP0002139_abnormal_hepatobiliary_system2.58857849
7MP0003191_abnormal_cellular_cholesterol2.54739870
8MP0005666_abnormal_adipose_tissue2.48958423
9MP0004130_abnormal_muscle_cell2.44459241
10MP0005275_abnormal_skin_tensile2.38478912
11MP0010234_abnormal_vibrissa_follicle2.37269523
12MP0010329_abnormal_lipoprotein_level2.26398419
13MP0003186_abnormal_redox_activity2.15315669
14MP0005085_abnormal_gallbladder_physiolo2.10575405
15MP0005360_urolithiasis2.01946633
16MP0010155_abnormal_intestine_physiology1.96817322
17MP0004185_abnormal_adipocyte_glucose1.93997121
18MP0002971_abnormal_brown_adipose1.87627964
19MP0009379_abnormal_foot_pigmentation1.86282298
20MP0002166_altered_tumor_susceptibility1.84162429
21MP0005166_decreased_susceptibility_to1.78297870
22MP0001835_abnormal_antigen_presentation1.76207632
23MP0003279_aneurysm1.75616115
24MP0002118_abnormal_lipid_homeostasis1.74664173
25MP0005375_adipose_tissue_phenotype1.72976566
26MP0009785_altered_susceptibility_to1.69690975
27MP0005165_increased_susceptibility_to1.66809811
28MP0003075_altered_response_to1.66787008
29MP0008875_abnormal_xenobiotic_pharmacok1.61917211
30MP0004019_abnormal_vitamin_homeostasis1.61396979
31MP0002876_abnormal_thyroid_physiology1.61395026
32MP0005332_abnormal_amino_acid1.52753626
33MP0004510_myositis1.51296376
34MP0005535_abnormal_body_temperature1.49682309
35MP0003183_abnormal_peptide_metabolism1.48570259
36MP0002254_reproductive_system_inflammat1.48549546
37MP0000685_abnormal_immune_system1.47485772
38MP0001853_heart_inflammation1.44449430
39MP0000609_abnormal_liver_physiology1.43186725
40MP0003436_decreased_susceptibility_to1.43029583
41MP0000858_altered_metastatic_potential1.42511201
42MP0003806_abnormal_nucleotide_metabolis1.42223203
43MP0005584_abnormal_enzyme/coenzyme_acti1.41973722
44MP0004264_abnormal_extraembryonic_tissu1.39703822
45MP0000372_irregular_coat_pigmentation1.38725454
46MP0005334_abnormal_fat_pad1.37535236
47MP0005503_abnormal_tendon_morphology1.36523778
48MP0001666_abnormal_nutrient_absorption1.35878506
49MP0002822_catalepsy1.35321456
50MP0000013_abnormal_adipose_tissue1.34158266
51MP0003868_abnormal_feces_composition1.34023464
52MP0000343_altered_response_to1.32605066
53MP0005083_abnormal_biliary_tract1.30673981
54MP0002060_abnormal_skin_morphology1.29809443
55MP0009115_abnormal_fat_cell1.29188411
56MP0001533_abnormal_skeleton_physiology1.26643159
57MP0009643_abnormal_urine_homeostasis1.26258119
58MP0005257_abnormal_intraocular_pressure1.26238346
59MP0002148_abnormal_hypersensitivity_rea1.25504967
60MP0001958_emphysema1.25368202
61MP0009840_abnormal_foam_cell1.25203256
62MP0002006_tumorigenesis1.24976187
63MP0009333_abnormal_splenocyte_physiolog1.23966348
64MP0003866_abnormal_defecation1.23648255
65MP0002452_abnormal_antigen_presenting1.20893526
66MP0005025_abnormal_response_to1.20299072
67MP0002837_dystrophic_cardiac_calcinosis1.20159439
68MP0005023_abnormal_wound_healing1.18992098
69MP0005164_abnormal_response_to1.18550058
70MP0010386_abnormal_urinary_bladder1.17569378
71MP0005319_abnormal_enzyme/_coenzyme1.17532704
72MP0002419_abnormal_innate_immunity1.16682946
73MP0003656_abnormal_erythrocyte_physiolo1.16265404
74MP0000465_gastrointestinal_hemorrhage1.16230544
75MP0006036_abnormal_mitochondrial_physio1.15705906
76MP0002277_abnormal_respiratory_mucosa1.15420976
77MP0003303_peritoneal_inflammation1.15016424
78MP0008469_abnormal_protein_level1.14372060
79MP0009764_decreased_sensitivity_to1.13530828
80MP0003329_amyloid_beta_deposits1.12097787
81MP0002970_abnormal_white_adipose1.10762254
82MP0005058_abnormal_lysosome_morphology1.10672213
83MP0005464_abnormal_platelet_physiology1.10352025
84MP0003950_abnormal_plasma_membrane1.09957742
85MP0001663_abnormal_digestive_system1.09859283
86MP0000003_abnormal_adipose_tissue1.06993904
87MP0001873_stomach_inflammation1.06476277
88MP0001542_abnormal_bone_strength1.05606893
89MP0003195_calcinosis1.05544338
90MP0004947_skin_inflammation1.04572274
91MP0003705_abnormal_hypodermis_morpholog1.04084759
92MP0001756_abnormal_urination1.02681546
93MP0008260_abnormal_autophagy1.01097289
94MP0005000_abnormal_immune_tolerance0.99484728
95MP0003959_abnormal_lean_body0.99481321
96MP0004272_abnormal_basement_membrane0.99198026
97MP0005671_abnormal_response_to0.98236388
98MP0002295_abnormal_pulmonary_circulatio0.97068624
99MP0001790_abnormal_immune_system0.96416907
100MP0005387_immune_system_phenotype0.96416907
101MP0005501_abnormal_skin_physiology0.95413716
102MP0003252_abnormal_bile_duct0.95017998
103MP0004883_abnormal_blood_vessel0.95004880
104MP0003690_abnormal_glial_cell0.94946931
105MP0002933_joint_inflammation0.94526538
106MP0003453_abnormal_keratinocyte_physiol0.93510645
107MP0001764_abnormal_homeostasis0.92480247
108MP0009384_cardiac_valve_regurgitation0.92259327
109MP0001881_abnormal_mammary_gland0.92156026
110MP0002136_abnormal_kidney_physiology0.92110399
111MP0001845_abnormal_inflammatory_respons0.92068694
112MP0001819_abnormal_immune_cell0.92012647
113MP0003011_delayed_dark_adaptation0.91603279
114MP0001661_extended_life_span0.90861000
115MP0001879_abnormal_lymphatic_vessel0.90420756
116MP0003638_abnormal_response/metabolism_0.90082734
117MP0009763_increased_sensitivity_to0.89984825
118MP0003315_abnormal_perineum_morphology0.89810024
119MP0004381_abnormal_hair_follicle0.89340707
120MP0001216_abnormal_epidermal_layer0.89296154
121MP0004782_abnormal_surfactant_physiolog0.89113564
122MP0002420_abnormal_adaptive_immunity0.88999185
123MP0000249_abnormal_blood_vessel0.88571617
124MP0002877_abnormal_melanocyte_morpholog0.86533666
125MP0003566_abnormal_cell_adhesion0.86122068
126MP0002723_abnormal_immune_serum0.85500621
127MP0005408_hypopigmentation0.85281783
128MP0000490_abnormal_crypts_of0.84187826
129MP0002078_abnormal_glucose_homeostasis0.83280577
130MP0002638_abnormal_pupillary_reflex0.82824086
131MP0001800_abnormal_humoral_immune0.82444522
132MP0005381_digestive/alimentary_phenotyp0.81934632
133MP0005448_abnormal_energy_balance0.81069462
134MP0002998_abnormal_bone_remodeling0.81020168
135MP0006082_CNS_inflammation0.79466708
136MP0005084_abnormal_gallbladder_morpholo0.79389856
137MP0005330_cardiomyopathy0.79242838
138MP0003045_fibrosis0.78401432
139MP0002796_impaired_skin_barrier0.78261829
140MP0000604_amyloidosis0.78204032
141MP0005390_skeleton_phenotype0.75916209
142MP0010368_abnormal_lymphatic_system0.75488725

Predicted human phenotypes

RankGene SetZ-score
1Hypothermia (HP:0002045)4.55344293
2Glomerulonephritis (HP:0000099)4.30101828
3Abnormality of fatty-acid metabolism (HP:0004359)3.86524000
4Malnutrition (HP:0004395)3.72826615
5Abnormality of aromatic amino acid family metabolism (HP:0004338)3.40911063
6Oligomenorrhea (HP:0000876)3.34596870
7Increased muscle lipid content (HP:0009058)3.30034715
8Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.28129413
9Hyperglycinuria (HP:0003108)3.25447632
10Hepatic necrosis (HP:0002605)3.23519542
11Hypertriglyceridemia (HP:0002155)3.14868522
12Complement deficiency (HP:0004431)3.11327868
13Acanthosis nigricans (HP:0000956)3.07944105
14Dicarboxylic aciduria (HP:0003215)3.07681372
15Abnormality of dicarboxylic acid metabolism (HP:0010995)3.07681372
16Xanthomatosis (HP:0000991)3.06846082
17Abnormality of glycolipid metabolism (HP:0010969)2.96024582
18Abnormality of liposaccharide metabolism (HP:0010968)2.96024582
19Abnormality of glycosphingolipid metabolism (HP:0004343)2.96024582
20Hypoglycemic coma (HP:0001325)2.93395069
21Intrahepatic cholestasis (HP:0001406)2.86311438
22Generalized aminoaciduria (HP:0002909)2.80194001
23Abnormality of serine family amino acid metabolism (HP:0010894)2.78029472
24Abnormality of glycine metabolism (HP:0010895)2.78029472
25Hyperlipoproteinemia (HP:0010980)2.75820266
26Hyperammonemia (HP:0001987)2.74717293
27Abnormal hemoglobin (HP:0011902)2.73387025
28Distal lower limb muscle weakness (HP:0009053)2.71502194
29Abnormality of proline metabolism (HP:0010907)2.71281109
30Hydroxyprolinuria (HP:0003080)2.71281109
31Hyperactive renin-angiotensin system (HP:0000841)2.68200517
32Myoglobinuria (HP:0002913)2.67179506
33Systemic lupus erythematosus (HP:0002725)2.66710306
34Elevated erythrocyte sedimentation rate (HP:0003565)2.63729629
35Acute encephalopathy (HP:0006846)2.62755000
36Right ventricular cardiomyopathy (HP:0011663)2.62230287
37Hepatocellular necrosis (HP:0001404)2.61846589
38Cerebral edema (HP:0002181)2.61226516
39Alopecia of scalp (HP:0002293)2.58054674
40Ketosis (HP:0001946)2.54595592
41Growth hormone excess (HP:0000845)2.54555067
42Vacuolated lymphocytes (HP:0001922)2.53321450
43Abnormality of macrophages (HP:0004311)2.52012334
44Neonatal hypoglycemia (HP:0001998)2.51508823
45Pustule (HP:0200039)2.50272792
46Vascular calcification (HP:0004934)2.41815731
47Acute necrotizing encephalopathy (HP:0006965)2.38432920
48Pancreatitis (HP:0001733)2.38175413
49Delayed CNS myelination (HP:0002188)2.38139055
50Abnormality of complement system (HP:0005339)2.37618889
51Nausea (HP:0002018)2.35340855
52Abnormal mitochondria in muscle tissue (HP:0008316)2.35242654
53Abnormality of glutamine family amino acid metabolism (HP:0010902)2.34224191
54Deep venous thrombosis (HP:0002625)2.33542262
55Myocardial infarction (HP:0001658)2.32882302
56Prolonged partial thromboplastin time (HP:0003645)2.31254012
57Amyloidosis (HP:0011034)2.30619727
58Conjugated hyperbilirubinemia (HP:0002908)2.30010981
59Rhabdomyolysis (HP:0003201)2.29046071
60Bone cyst (HP:0012062)2.27914114
61Abnormality of the common coagulation pathway (HP:0010990)2.27364075
62Lethargy (HP:0001254)2.25707706
63Mitochondrial inheritance (HP:0001427)2.22886527
64Thick nail (HP:0001805)2.22536066
65Abnormality of pyrimidine metabolism (HP:0004353)2.22126161
66Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.21919810
67Decreased activity of mitochondrial respiratory chain (HP:0008972)2.21919810
68Increased intramyocellular lipid droplets (HP:0012240)2.21828784
69Hypoalphalipoproteinemia (HP:0003233)2.19810182
70Alkalosis (HP:0001948)2.19478189
71Purpura (HP:0000979)2.17043154
72Axonal loss (HP:0003447)2.14744273
73Cardiovascular calcification (HP:0011915)2.12372755
74Erythema (HP:0010783)2.12294171
75Ketoacidosis (HP:0001993)2.11260737
76Renal cortical cysts (HP:0000803)2.09810760
77Fat malabsorption (HP:0002630)2.07874756
78Recurrent bacterial skin infections (HP:0005406)2.05750156
79Ileus (HP:0002595)2.04951464
80Progressive macrocephaly (HP:0004481)2.04648286
81Lactic acidosis (HP:0003128)2.04226922
82Cholecystitis (HP:0001082)2.04175548
83Abnormal gallbladder physiology (HP:0012438)2.04175548
84Protrusio acetabuli (HP:0003179)2.04064674
85Chronic otitis media (HP:0000389)2.03552511
86Recurrent abscess formation (HP:0002722)2.03386486
87Glucose intolerance (HP:0000833)2.03342999
88Abnormal glucose tolerance (HP:0001952)2.02732356
89Eczematoid dermatitis (HP:0000976)2.02515389
90Interstitial pulmonary disease (HP:0006530)2.02434516
91Broad metatarsal (HP:0001783)2.01198459
92Vomiting (HP:0002013)2.00778461
93Polygenic inheritance (HP:0010982)1.99904268
94Conjunctival hamartoma (HP:0100780)1.98908132
95Osteolytic defects of the hand bones (HP:0009699)1.98486516
96Osteolytic defects of the phalanges of the hand (HP:0009771)1.98486516
97Lipid accumulation in hepatocytes (HP:0006561)1.98339700
98Recurrent gram-negative bacterial infections (HP:0005420)1.97522821
99Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.97018660
100Gingivitis (HP:0000230)1.96252125
101Vertebral compression fractures (HP:0002953)1.95573690
102Premature rupture of membranes (HP:0001788)1.95563944
103Abnormal cartilage morphology (HP:0002763)1.95315619
104Reduced antithrombin III activity (HP:0001976)1.95067795
105Abnormality of the distal phalanges of the toes (HP:0010182)1.94934090
106Muscle stiffness (HP:0003552)1.94745294
107Decreased circulating renin level (HP:0003351)1.94546855
108Increased CSF lactate (HP:0002490)1.94189471
109Congenital ichthyosiform erythroderma (HP:0007431)1.93871762
110Cerebral hemorrhage (HP:0001342)1.93859086
111Hypergammaglobulinemia (HP:0010702)1.93677464
112Abnormality of the intrinsic pathway (HP:0010989)1.90760505
113Prolonged neonatal jaundice (HP:0006579)1.90279622
114Abnormality of mucopolysaccharide metabolism (HP:0011020)1.89969534
115Abnormality of polysaccharide metabolism (HP:0011012)1.89969534
116Abnormality of glycosaminoglycan metabolism (HP:0004371)1.89969534
117Reduced subcutaneous adipose tissue (HP:0003758)1.89379998
118Beaking of vertebral bodies (HP:0004568)1.88967352
119Colitis (HP:0002583)1.88451818
120Premature loss of primary teeth (HP:0006323)1.88057843
121Loss of speech (HP:0002371)1.87947148
122Hyperglycinemia (HP:0002154)1.86159639
123Abnormality of monocarboxylic acid metabolism (HP:0010996)1.85981687
124Orthostatic hypotension (HP:0001278)1.85426983
125Esophageal neoplasm (HP:0100751)1.85321151
126Neoplasm of head and neck (HP:0012288)1.85321151
127Myositis (HP:0100614)1.85317088
128Recurrent bronchitis (HP:0002837)1.85042735
129Abnormality of the nasal mucosa (HP:0000433)1.84368451
130Aortic aneurysm (HP:0004942)1.83415764
131Pulmonary infiltrates (HP:0002113)1.83412054
132Urinary glycosaminoglycan excretion (HP:0003541)1.82085284
133Mucopolysacchariduria (HP:0008155)1.82085284
134Menorrhagia (HP:0000132)1.82022017
135Orchitis (HP:0100796)1.81314631
136Methylmalonic aciduria (HP:0012120)1.79977005
137Petechiae (HP:0000967)1.78604662
138Nephritis (HP:0000123)1.78087071
139Dysostosis multiplex (HP:0000943)1.77843052
140Increased IgE level (HP:0003212)1.77059194
141Palmoplantar hyperkeratosis (HP:0000972)1.77022060
142Hyperpituitarism (HP:0010514)1.75923093
143Brushfield spots (HP:0001088)1.75825859
144Respiratory failure (HP:0002878)1.74793165
145Tetraparesis (HP:0002273)1.73730702
146Cerebral palsy (HP:0100021)1.73442360
147Renal Fanconi syndrome (HP:0001994)1.73420123
148Skin rash (HP:0000988)1.73371504
149Joint hemorrhage (HP:0005261)1.73214368
150Impaired platelet aggregation (HP:0003540)1.72891178
151Abnormal platelet function (HP:0011869)1.72891178
152Metabolic acidosis (HP:0001942)1.71786415
153Hemorrhage of the eye (HP:0011885)1.71681502
154Multiple enchondromatosis (HP:0005701)1.71492279
155Hypobetalipoproteinemia (HP:0003563)1.71264447
156Nasal polyposis (HP:0100582)1.70490559
157Hypolipoproteinemia (HP:0010981)1.70035777
158Abnormality of nucleobase metabolism (HP:0010932)1.70026531
159Epidermoid cyst (HP:0200040)1.69298489
160Glomerulosclerosis (HP:0000096)1.68600395
161Progressive neurologic deterioration (HP:0002344)1.67819758
162Increased IgM level (HP:0003496)1.66834432
163Mediastinal lymphadenopathy (HP:0100721)1.66752070

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA24.97038823
2BCKDK4.10220316
3TESK23.57248886
4NME22.98988510
5ERN12.97543884
6CAMK1D2.59952704
7TRIB32.59312725
8VRK22.48089327
9SIK12.17145950
10TBK12.08082496
11TGFBR22.06294145
12PIM22.05488807
13LIMK12.04988317
14FLT32.04873717
15KIT1.96558746
16MYLK1.93031073
17FGFR41.82629915
18MST1R1.73810448
19GRK51.60314833
20TEC1.56353568
21KDR1.56318185
22ZAP701.51842095
23IKBKE1.49897989
24TYK21.49302200
25MST41.47059949
26JAK31.45946151
27MAP4K11.45512985
28MAP3K121.44009313
29GRK71.42382428
30MAP2K31.38012678
31ARAF1.37309653
32PDK21.31928345
33NTRK11.31311630
34CAMK1G1.30488086
35MATK1.25193739
36ILK1.24782005
37MAP3K141.24692226
38NEK91.24539368
39CAMKK21.18843872
40LRRK21.18788927
41MAP2K11.18764542
42PAK41.18406109
43MAPKAPK51.17980695
44MAP3K111.17605105
45JAK11.15571887
46MAP3K31.14024386
47PDK31.11393927
48PDK41.11393927
49EPHA31.10444776
50TIE11.09421989
51EPHB11.08433877
52TAOK21.07369923
53MAPKAPK31.05406655
54CSF1R1.04977222
55DAPK11.03138190
56HIPK21.00631789
57MAP2K20.97731349
58TRPM70.97687657
59PKN20.97256462
60PTK20.95537405
61TXK0.94406930
62INSRR0.94140574
63IRAK30.92313927
64MAP3K20.92257786
65TAOK30.90914471
66PIK3CG0.89538900
67LMTK20.85997661
68PTK60.85666829
69NLK0.84193574
70BTK0.83783208
71ITK0.83030780
72MAPK150.82766141
73PRPF4B0.82243727
74SIK30.81060479
75ADRBK20.80330955
76SYK0.79771723
77BMX0.79674455
78FGFR30.78572791
79PTK2B0.77760935
80RIPK10.77627093
81TNK20.76576168
82IRAK40.75902120
83PRKAA20.72532640
84JAK20.69977526
85LCK0.68647537
86SMG10.68431857
87MAPK40.67262647
88IKBKB0.67041801
89MET0.65542460
90STK100.63548709
91IGF1R0.63323676
92ABL20.62782513
93DAPK30.60408803
94RIPK40.60079929
95PRKG20.59149537
96GRK60.57925473
97IRAK10.57216949
98MAPK120.57185550
99ACVR1B0.56772904
100RET0.56565821
101MAP3K130.56175634
102TAOK10.54716820
103MAPKAPK20.54380406
104STK160.54100245
105CDC42BPA0.53330617
106PRKCH0.52747424
107MAP3K70.52373016
108PRKCI0.51991845
109MUSK0.50985937
110TESK10.49174468
111MAPK110.48183784
112DDR20.48141203
113FER0.47826536
114DMPK0.47517347
115ADRBK10.46007836
116BLK0.45274498
117PDPK10.44967703
118BMPR20.44655173
119CSK0.43944488
120PIK3CA0.43563704
121PRKCQ0.43354191
122MAP2K60.42710150
123TGFBR10.41701475
124MAP3K10.41146029
125LYN0.40628473
126EPHB20.40545810
127NME10.40024024
128PRKD10.39563483
129MOS0.38683952
130SRC0.34987418
131OXSR10.33953340
132PHKG10.33818225
133PHKG20.33818225
134PAK10.32317767
135CAMK2G0.31931653
136MAP2K70.31764640
137MAP3K60.30156552
138PRKCD0.28965218
139STK390.28416857
140GSK3A0.28292425
141MAPK70.25395582

Predicted pathways (KEGG)

RankGene SetZ-score
1Propanoate metabolism_Homo sapiens_hsa006403.46524588
2Fatty acid degradation_Homo sapiens_hsa000713.17473591
3Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.08730275
4Cyanoamino acid metabolism_Homo sapiens_hsa004602.88951184
5PPAR signaling pathway_Homo sapiens_hsa033202.88626844
6Fatty acid metabolism_Homo sapiens_hsa012122.84425896
7Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.54216898
8Allograft rejection_Homo sapiens_hsa053302.51690368
9Asthma_Homo sapiens_hsa053102.40704809
10Primary bile acid biosynthesis_Homo sapiens_hsa001202.39608313
11Fatty acid elongation_Homo sapiens_hsa000622.37036860
12Graft-versus-host disease_Homo sapiens_hsa053322.18994951
13Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.06502581
14Tyrosine metabolism_Homo sapiens_hsa003502.02646959
15Caffeine metabolism_Homo sapiens_hsa002322.02086088
16Fatty acid biosynthesis_Homo sapiens_hsa000612.01222200
17Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.99588294
18Peroxisome_Homo sapiens_hsa041461.96539689
19Pyruvate metabolism_Homo sapiens_hsa006201.81567971
20Tryptophan metabolism_Homo sapiens_hsa003801.71843856
21Fructose and mannose metabolism_Homo sapiens_hsa000511.70821564
22Antigen processing and presentation_Homo sapiens_hsa046121.69281367
23Type I diabetes mellitus_Homo sapiens_hsa049401.68954332
24Glycerolipid metabolism_Homo sapiens_hsa005611.68447013
25Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.67185422
26Pentose and glucuronate interconversions_Homo sapiens_hsa000401.66778927
27Histidine metabolism_Homo sapiens_hsa003401.65791607
28Phenylalanine metabolism_Homo sapiens_hsa003601.64609213
29Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.62956935
30Complement and coagulation cascades_Homo sapiens_hsa046101.60818073
31Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.58284028
32Chemical carcinogenesis_Homo sapiens_hsa052041.57377306
33beta-Alanine metabolism_Homo sapiens_hsa004101.57010497
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.56173044
35Sulfur metabolism_Homo sapiens_hsa009201.53981780
36Galactose metabolism_Homo sapiens_hsa000521.52313934
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.52209763
38Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.50888288
39Oxidative phosphorylation_Homo sapiens_hsa001901.50778336
40Staphylococcus aureus infection_Homo sapiens_hsa051501.47723191
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.45120161
42Viral myocarditis_Homo sapiens_hsa054161.35561825
43Mineral absorption_Homo sapiens_hsa049781.32731900
44Arginine and proline metabolism_Homo sapiens_hsa003301.25658307
45Carbon metabolism_Homo sapiens_hsa012001.24800525
46Fat digestion and absorption_Homo sapiens_hsa049751.23986748
47Parkinsons disease_Homo sapiens_hsa050121.23761098
48Influenza A_Homo sapiens_hsa051641.20163333
49Adipocytokine signaling pathway_Homo sapiens_hsa049201.17037094
50Renin-angiotensin system_Homo sapiens_hsa046141.14843741
51Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.12432251
52Butanoate metabolism_Homo sapiens_hsa006501.09710769
53Folate biosynthesis_Homo sapiens_hsa007901.08015437
54Hepatitis C_Homo sapiens_hsa051601.07869145
55Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.01597429
56Alzheimers disease_Homo sapiens_hsa050101.01532407
57Steroid hormone biosynthesis_Homo sapiens_hsa001400.95364615
58Starch and sucrose metabolism_Homo sapiens_hsa005000.94770642
59Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.94035533
60Ribosome_Homo sapiens_hsa030100.94009201
61Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.89421852
62Tuberculosis_Homo sapiens_hsa051520.89209606
63Glutathione metabolism_Homo sapiens_hsa004800.88874479
64Herpes simplex infection_Homo sapiens_hsa051680.87589249
65Protein export_Homo sapiens_hsa030600.86053895
66Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.84030160
67Retinol metabolism_Homo sapiens_hsa008300.79685235
68Sulfur relay system_Homo sapiens_hsa041220.79123910
69Drug metabolism - other enzymes_Homo sapiens_hsa009830.77680490
70Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.77422213
71NF-kappa B signaling pathway_Homo sapiens_hsa040640.77230549
72Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.76626616
73Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.76035008
74Pentose phosphate pathway_Homo sapiens_hsa000300.74109636
75ABC transporters_Homo sapiens_hsa020100.73354631
76Malaria_Homo sapiens_hsa051440.68722896
77Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.67874695
78Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.67659413
79Arginine biosynthesis_Homo sapiens_hsa002200.66391575
80Pertussis_Homo sapiens_hsa051330.65361766
81Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.63477276
82Measles_Homo sapiens_hsa051620.61467997
83Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.61279617
84alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.58255096
85Leishmaniasis_Homo sapiens_hsa051400.57657419
86Prion diseases_Homo sapiens_hsa050200.57500561
87Lysosome_Homo sapiens_hsa041420.56738480
88Arachidonic acid metabolism_Homo sapiens_hsa005900.56308812
89Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.56237377
90Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.54885422
91Rheumatoid arthritis_Homo sapiens_hsa053230.53913107
92Sphingolipid metabolism_Homo sapiens_hsa006000.51870119
93Primary immunodeficiency_Homo sapiens_hsa053400.50978215
94Insulin resistance_Homo sapiens_hsa049310.50420790
95Metabolic pathways_Homo sapiens_hsa011000.50012860
96Glycosaminoglycan degradation_Homo sapiens_hsa005310.49953753
97Other glycan degradation_Homo sapiens_hsa005110.45724378
98Huntingtons disease_Homo sapiens_hsa050160.45565201
99Linoleic acid metabolism_Homo sapiens_hsa005910.44854769
100Protein digestion and absorption_Homo sapiens_hsa049740.44559225
101TNF signaling pathway_Homo sapiens_hsa046680.44529418
102Proteasome_Homo sapiens_hsa030500.44071635
103Hematopoietic cell lineage_Homo sapiens_hsa046400.43996100
104Biosynthesis of amino acids_Homo sapiens_hsa012300.43373638
105Leukocyte transendothelial migration_Homo sapiens_hsa046700.42348954
106Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.41467256
107Salmonella infection_Homo sapiens_hsa051320.41427206
108Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.41148630
109Osteoclast differentiation_Homo sapiens_hsa043800.41030299
110Bile secretion_Homo sapiens_hsa049760.40649727
111Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.39565875
112Vitamin digestion and absorption_Homo sapiens_hsa049770.39245516
113Autoimmune thyroid disease_Homo sapiens_hsa053200.39157987
114Vibrio cholerae infection_Homo sapiens_hsa051100.38427749
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.37383498
116Chemokine signaling pathway_Homo sapiens_hsa040620.37316955
117ECM-receptor interaction_Homo sapiens_hsa045120.36966398
118Pancreatic secretion_Homo sapiens_hsa049720.33655987
119SNARE interactions in vesicular transport_Homo sapiens_hsa041300.33404735
120AMPK signaling pathway_Homo sapiens_hsa041520.32927034
121Toxoplasmosis_Homo sapiens_hsa051450.32744411
122Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.31872451
123Intestinal immune network for IgA production_Homo sapiens_hsa046720.31446868
124Systemic lupus erythematosus_Homo sapiens_hsa053220.31193848
125African trypanosomiasis_Homo sapiens_hsa051430.31060734
126Nitrogen metabolism_Homo sapiens_hsa009100.29817728
127Jak-STAT signaling pathway_Homo sapiens_hsa046300.29280638
128RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.29230475
129Phagosome_Homo sapiens_hsa041450.28956188
130Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.28597998
131Amoebiasis_Homo sapiens_hsa051460.27910417
132Toll-like receptor signaling pathway_Homo sapiens_hsa046200.26447103
133Legionellosis_Homo sapiens_hsa051340.25461105

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