IGFBP6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein heterotrimerization (GO:0070208)7.45115598
2type B pancreatic cell proliferation (GO:0044342)6.11763173
3collagen fibril organization (GO:0030199)5.57351820
4keratan sulfate catabolic process (GO:0042340)5.07050196
5extracellular fibril organization (GO:0043206)4.95154228
6sequestering of extracellular ligand from receptor (GO:0035581)4.93223448
7regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.69111373
8extracellular matrix assembly (GO:0085029)4.51164742
9cell migration involved in heart development (GO:0060973)4.47124925
10fibril organization (GO:0097435)4.29812214
11basement membrane organization (GO:0071711)4.18150000
12collagen metabolic process (GO:0032963)4.13771960
13skin morphogenesis (GO:0043589)4.10255506
14peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)4.06298959
15protein retention in ER lumen (GO:0006621)4.06161102
16adhesion of symbiont to host (GO:0044406)4.06159520
17regulation of vascular endothelial growth factor signaling pathway (GO:1900746)4.03477429
18multicellular organismal macromolecule metabolic process (GO:0044259)4.03199324
19collagen catabolic process (GO:0030574)4.02921110
20negative regulation of smooth muscle cell migration (GO:0014912)3.91667107
21apoptotic cell clearance (GO:0043277)3.89539402
22maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.88964468
23glomerular basement membrane development (GO:0032836)3.83716223
24neuron projection extension involved in neuron projection guidance (GO:1902284)3.83682822
25axon extension involved in axon guidance (GO:0048846)3.83682822
26multicellular organismal metabolic process (GO:0044236)3.82766167
27blood vessel maturation (GO:0001955)3.82590500
28multicellular organismal catabolic process (GO:0044243)3.77958325
29cellular response to vitamin (GO:0071295)3.77450703
30mesenchymal-epithelial cell signaling (GO:0060638)3.69869214
31negative regulation of leukocyte chemotaxis (GO:0002689)3.67562745
32chondrocyte proliferation (GO:0035988)3.65421495
33Golgi transport vesicle coating (GO:0048200)3.58944081
34COPI coating of Golgi vesicle (GO:0048205)3.58944081
35endodermal cell differentiation (GO:0035987)3.52458042
36bone trabecula formation (GO:0060346)3.49707909
37opsonization (GO:0008228)3.48584808
38peptidyl-proline hydroxylation (GO:0019511)3.40164305
39extracellular matrix disassembly (GO:0022617)3.39580981
40regulation of extracellular matrix disassembly (GO:0010715)3.38250063
41regulation of plasminogen activation (GO:0010755)3.38227365
42substrate-dependent cell migration (GO:0006929)3.37258054
43plasma membrane repair (GO:0001778)3.37131047
44protein maturation by protein folding (GO:0022417)3.34452427
45negative regulation of complement activation (GO:0045916)3.30570811
46positive regulation of p38MAPK cascade (GO:1900745)3.29763699
47endocardial cushion development (GO:0003197)3.27750146
48positive regulation of respiratory burst (GO:0060267)3.27474610
49vascular endothelial growth factor signaling pathway (GO:0038084)3.26613283
50hyaluronan catabolic process (GO:0030214)3.26425405
51tooth mineralization (GO:0034505)3.25784839
52protein hydroxylation (GO:0018126)3.25352371
53stress fiber assembly (GO:0043149)3.16590052
54negative regulation of cardiac muscle tissue growth (GO:0055022)3.16013988
55negative regulation of heart growth (GO:0061117)3.16013988
56positive regulation of blood vessel endothelial cell migration (GO:0043536)3.15868098
57glial cell migration (GO:0008347)3.15834921
58hemidesmosome assembly (GO:0031581)3.12971348
59protein localization to endosome (GO:0036010)3.10707454
60dermatan sulfate biosynthetic process (GO:0030208)3.10165407
61hypotonic response (GO:0006971)3.07762161
62regulation of macrophage cytokine production (GO:0010935)3.06982339
63glomerular filtration (GO:0003094)3.03882656
64lymphangiogenesis (GO:0001946)3.00731124
65negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)3.00175307
66negative regulation of chondrocyte differentiation (GO:0032331)2.99670278
67low-density lipoprotein particle clearance (GO:0034383)2.98704767
68epithelial cell-cell adhesion (GO:0090136)2.97540420
69renal filtration (GO:0097205)2.96782181
70smooth muscle tissue development (GO:0048745)2.96533513
71membrane raft organization (GO:0031579)2.93324148
72middle ear morphogenesis (GO:0042474)2.91716723
73regulation of p38MAPK cascade (GO:1900744)2.91391842
74cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.90988306
75peripheral nervous system axon ensheathment (GO:0032292)2.89347529
76myelination in peripheral nervous system (GO:0022011)2.89347529
77regulation of metalloenzyme activity (GO:0048552)2.88757547
78planar cell polarity pathway involved in neural tube closure (GO:0090179)2.87939664
79positive regulation of macrophage cytokine production (GO:0060907)2.86375498
80retina vasculature morphogenesis in camera-type eye (GO:0061299)2.85103216
81cellular response to vitamin D (GO:0071305)2.84625330
82detection of molecule of bacterial origin (GO:0032490)2.83852087
83focal adhesion assembly (GO:0048041)2.81983277
84cell-substrate adherens junction assembly (GO:0007045)2.81983277
85positive regulation of osteoblast proliferation (GO:0033690)2.81330519
86barbed-end actin filament capping (GO:0051016)2.81045154
87cellular response to cadmium ion (GO:0071276)2.80784682
88UV protection (GO:0009650)2.79915732
89adherens junction assembly (GO:0034333)2.79831391
90extracellular matrix organization (GO:0030198)2.78696297
91dermatan sulfate metabolic process (GO:0030205)2.78505581
92endothelial cell morphogenesis (GO:0001886)2.78267456
93cortical actin cytoskeleton organization (GO:0030866)2.78096310
94negative regulation of BMP signaling pathway (GO:0030514)2.77880596
95extracellular structure organization (GO:0043062)2.77664610
96heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.77386854
97vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.76799533
98negative regulation of nitric oxide biosynthetic process (GO:0045019)2.76092293
99negative regulation of nitric-oxide synthase activity (GO:0051001)2.74894847
100skeletal muscle adaptation (GO:0043501)2.74850452
101regulation of integrin-mediated signaling pathway (GO:2001044)2.74329944
102ovulation from ovarian follicle (GO:0001542)2.73912111
103metanephric mesenchyme development (GO:0072075)2.71533908
104cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.71092037
105cell-substrate junction assembly (GO:0007044)2.70950624
106positive regulation of extracellular matrix organization (GO:1903055)2.70744624
107protein localization to cell surface (GO:0034394)2.70176020
108regulation of smooth muscle cell migration (GO:0014910)2.69114046
109negative regulation of cartilage development (GO:0061037)2.68706013
110venous blood vessel morphogenesis (GO:0048845)2.68677365
111regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.68473111
112dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.66756944
113cell migration involved in sprouting angiogenesis (GO:0002042)2.66197785
114surfactant homeostasis (GO:0043129)2.65352893
115positive regulation of endothelial cell apoptotic process (GO:2000353)2.63997336
116regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.63470890
117negative regulation of fatty acid transport (GO:2000192)2.62861009
118cellular response to interferon-alpha (GO:0035457)2.62537973
119wound healing, spreading of epidermal cells (GO:0035313)2.61095837
120cell adhesion mediated by integrin (GO:0033627)2.60077104
121positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.59108747
122pathway-restricted SMAD protein phosphorylation (GO:0060389)2.56061424
123protein trimerization (GO:0070206)2.55760458
124blood vessel remodeling (GO:0001974)2.55204101
125protein targeting to plasma membrane (GO:0072661)2.53329848
126regulation of tight junction assembly (GO:2000810)2.53286446
127negative regulation of Rho protein signal transduction (GO:0035024)2.52781435
128negative regulation of protein activation cascade (GO:2000258)2.50901368
129regulation of endothelial cell differentiation (GO:0045601)2.49716965
130negative regulation of stress fiber assembly (GO:0051497)2.46917574
131complement activation, alternative pathway (GO:0006957)2.46118148
132regulation of skeletal muscle contraction (GO:0014819)2.46027269
133fibroblast migration (GO:0010761)2.45445179
134cardiac muscle cell proliferation (GO:0060038)2.45246051
135extracellular negative regulation of signal transduction (GO:1900116)2.42421213
136extracellular regulation of signal transduction (GO:1900115)2.42421213
137endothelial cell proliferation (GO:0001935)2.42228674
138substrate adhesion-dependent cell spreading (GO:0034446)2.40967146
139kidney mesenchyme development (GO:0072074)2.39864258
140cellular response to amino acid stimulus (GO:0071230)2.39080304
141adhesion of symbiont to host cell (GO:0044650)2.38909502
142virion attachment to host cell (GO:0019062)2.38909502
143muscle cell migration (GO:0014812)2.38861521
144trabecula formation (GO:0060343)2.38792161
145regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.38495762
146negative regulation of adherens junction organization (GO:1903392)2.37575406
147negative regulation of focal adhesion assembly (GO:0051895)2.37575406
148negative regulation of cell junction assembly (GO:1901889)2.37575406

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human5.05964700
2RARG_19884340_ChIP-ChIP_MEFs_Mouse4.54695385
3PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.72330143
4CLOCK_20551151_ChIP-Seq_293T_Human3.37628944
5PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.76997360
6TP63_17297297_ChIP-ChIP_HaCaT_Human2.67127219
7TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.65150541
8ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.56554168
9TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.34888874
10RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.19573630
11CJUN_26792858_Chip-Seq_BT549_Human2.10043954
12* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.96852158
13ESR2_21235772_ChIP-Seq_MCF-7_Human1.94423643
14RNF2_18974828_ChIP-Seq_MESCs_Mouse1.94041196
15EZH2_18974828_ChIP-Seq_MESCs_Mouse1.94041196
16EP300_21415370_ChIP-Seq_HL-1_Mouse1.93480863
17SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.93396246
18ESR1_21235772_ChIP-Seq_MCF-7_Human1.89403559
19* SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.85103211
20EED_16625203_ChIP-ChIP_MESCs_Mouse1.83122304
21* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.77192135
22TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.76727738
23NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.76229002
24* ELK3_25401928_ChIP-Seq_HUVEC_Human1.75206258
25TP53_22127205_ChIP-Seq_IMR90_Human1.74087307
26CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.73009262
27* SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.70616154
28* SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.67740067
29GATA2_21666600_ChIP-Seq_HMVEC_Human1.67322624
30CDX2_19796622_ChIP-Seq_MESCs_Mouse1.65781120
31THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.64574499
32EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.61489408
33TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.59331027
34SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.54773495
35POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.54073929
36STAT6_21828071_ChIP-Seq_BEAS2B_Human1.53865883
37* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.52777689
38* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.52101800
39TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.51675588
40HIF1A_21447827_ChIP-Seq_MCF-7_Human1.47967974
41JARID2_20075857_ChIP-Seq_MESCs_Mouse1.45593120
42* SA1_22415368_ChIP-Seq_MEFs_Mouse1.43964420
43KDM2B_26808549_Chip-Seq_SUP-B15_Human1.43264953
44NRF2_20460467_ChIP-Seq_MEFs_Mouse1.42469936
45NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.42469936
46BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.41798900
47PPAR_26484153_Chip-Seq_NCI-H1993_Human1.41082014
48LXR_22292898_ChIP-Seq_THP-1_Human1.37709443
49ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.36438004
50ESR1_20079471_ChIP-ChIP_T-47D_Human1.35660065
51* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.35598619
52TBX20_22080862_ChIP-Seq_HEART_Mouse1.34585406
53TBX20_22328084_ChIP-Seq_HEART_Mouse1.34585406
54KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.34571769
55* RACK7_27058665_Chip-Seq_MCF-7_Human1.34463887
56UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.34032065
57* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.33015122
58BRD4_25478319_ChIP-Seq_HGPS_Human1.32886786
59TP53_20018659_ChIP-ChIP_R1E_Mouse1.32045441
60* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.31300433
61SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.30295946
62TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.29562212
63* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.29461544
64* SMC1_22415368_ChIP-Seq_MEFs_Mouse1.29182593
65JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.28300051
66* KDM2B_26808549_Chip-Seq_K562_Human1.26355784
67P300_27058665_Chip-Seq_ZR-75-30cells_Human1.26171475
68SOX2_20726797_ChIP-Seq_SW620_Human1.26025411
69ZNF217_24962896_ChIP-Seq_MCF-7_Human1.25870784
70SOX9_24532713_ChIP-Seq_HFSC_Mouse1.25567859
71MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.25447076
72DROSHA_22980978_ChIP-Seq_HELA_Human1.23197989
73ZFP281_18757296_ChIP-ChIP_E14_Mouse1.22828673
74NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.21782848
75WT1_19549856_ChIP-ChIP_CCG9911_Human1.20817785
76TP53_18474530_ChIP-ChIP_U2OS_Human1.18909887
77JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.18600888
78TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.18267126
79SMAD_19615063_ChIP-ChIP_OVARY_Human1.15387719
80RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.14668249
81IKZF1_21737484_ChIP-ChIP_HCT116_Human1.12791364
82EZH2_27304074_Chip-Seq_ESCs_Mouse1.11787966
83DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.11768056
84ZNF263_19887448_ChIP-Seq_K562_Human1.09734282
85* TET1_21490601_ChIP-Seq_MESCs_Mouse1.08122241
86SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.07797815
87SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.07797815
88WT1_25993318_ChIP-Seq_PODOCYTE_Human1.07341098
89RNF2_27304074_Chip-Seq_ESCs_Mouse1.07334557
90KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.06697511
91* ATF3_27146783_Chip-Seq_COLON_Human1.06606549
92TP53_16413492_ChIP-PET_HCT116_Human1.06392578
93AHR_22903824_ChIP-Seq_MCF-7_Human1.05890011
94JARID2_20064375_ChIP-Seq_MESCs_Mouse1.05010417
95EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.03896062
96CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.03401639
97ERG_21242973_ChIP-ChIP_JURKAT_Human1.03310552
98P63_26484246_Chip-Seq_KERATINOCYTES_Human1.03249466
99CSB_26484114_Chip-Seq_FIBROBLAST_Human1.02880587
100UBF1/2_26484160_Chip-Seq_HMECs_Human1.02861803
101SUZ12_27294783_Chip-Seq_ESCs_Mouse1.01385231
102EGR1_19374776_ChIP-ChIP_THP-1_Human1.00267820
103NFIB_24661679_ChIP-Seq_LUNG_Mouse1.00194980
104PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.00008630
105ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.99932820
106RAD21_21589869_ChIP-Seq_MESCs_Mouse0.99037842
107* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.98665621
108FOXO3_23340844_ChIP-Seq_DLD1_Human0.97072586
109* EZH2_27294783_Chip-Seq_ESCs_Mouse0.95281041
110SMC3_22415368_ChIP-Seq_MEFs_Mouse0.93872797
111NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.93618289
112PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.92877107
113ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.90817364
114TET1_21451524_ChIP-Seq_MESCs_Mouse0.90802120
115NR3C1_23031785_ChIP-Seq_PC12_Mouse0.90521592
116EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.90485211
117SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.90335106
118KLF5_25053715_ChIP-Seq_YYC3_Human0.90236822
119TP53_23651856_ChIP-Seq_MEFs_Mouse0.90175339
120SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.90105938
121RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.89833434
122DNAJC2_21179169_ChIP-ChIP_NT2_Human0.89505476
123SALL4_18804426_ChIP-ChIP_XEN_Mouse0.87164797
124NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.86781542
125ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.86343066
126CTCF_27219007_Chip-Seq_ERYTHROID_Human0.86279089
127HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.86217843
128PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.85369897

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen8.38798229
2MP0005275_abnormal_skin_tensile6.26312943
3MP0005503_abnormal_tendon_morphology5.49159990
4MP0001958_emphysema4.28166771
5MP0003705_abnormal_hypodermis_morpholog3.28066038
6MP0003279_aneurysm3.24106104
7MP0006054_spinal_hemorrhage3.05445195
8MP0004272_abnormal_basement_membrane2.84095213
9MP0000751_myopathy2.71260487
10MP0005257_abnormal_intraocular_pressure2.28234658
11MP0010368_abnormal_lymphatic_system2.22254931
12MP0002108_abnormal_muscle_morphology2.09336996
13MP0000013_abnormal_adipose_tissue2.06662236
14MP0005508_abnormal_skeleton_morphology1.94426143
15MP0001542_abnormal_bone_strength1.92632132
16MP0002060_abnormal_skin_morphology1.92158391
17MP0003566_abnormal_cell_adhesion1.81315890
18MP0000750_abnormal_muscle_regeneration1.71514928
19MP0002295_abnormal_pulmonary_circulatio1.70849067
20MP0002837_dystrophic_cardiac_calcinosis1.68603318
21MP0001879_abnormal_lymphatic_vessel1.65592922
22MP0005623_abnormal_meninges_morphology1.63318832
23MP0005023_abnormal_wound_healing1.56163925
24MP0009384_cardiac_valve_regurgitation1.53967545
25MP0000749_muscle_degeneration1.48211017
26MP0009780_abnormal_chondrocyte_physiolo1.45699628
27MP0002877_abnormal_melanocyte_morpholog1.43753364
28MP0003091_abnormal_cell_migration1.42925646
29MP0005164_abnormal_response_to1.37932339
30MP0004883_abnormal_blood_vessel1.34935850
31MP0000343_altered_response_to1.26619453
32MP0003941_abnormal_skin_development1.24576310
33MP0000767_abnormal_smooth_muscle1.24280165
34MP0003045_fibrosis1.19756048
35MP0008004_abnormal_stomach_pH1.18459885
36MP0000759_abnormal_skeletal_muscle1.18292983
37MP0002133_abnormal_respiratory_system1.18229575
38MP0005388_respiratory_system_phenotype1.18229575
39MP0001849_ear_inflammation1.16878699
40MP0005670_abnormal_white_adipose1.16239940
41MP0003191_abnormal_cellular_cholesterol1.14358643
42MP0005595_abnormal_vascular_smooth1.14104087
43MP0000762_abnormal_tongue_morphology1.12512749
44MP0004130_abnormal_muscle_cell1.12313969
45MP0005369_muscle_phenotype1.11358517
46MP0003011_delayed_dark_adaptation1.07237393
47MP0000733_abnormal_muscle_development1.07147639
48MP0002896_abnormal_bone_mineralization1.06884413
49MP0004087_abnormal_muscle_fiber1.05905897
50MP0001243_abnormal_dermal_layer1.05774669
51MP0005390_skeleton_phenotype1.04508418
52MP0004233_abnormal_muscle_weight1.04223765
53MP0005058_abnormal_lysosome_morphology1.04001108
54MP0000003_abnormal_adipose_tissue1.03460791
55MP0009250_abnormal_appendicular_skeleto1.03237976
56MP0010352_gastrointestinal_tract_polyps1.02558524
57MP0002168_other_aberrant_phenotype1.02246341
58MP0001177_atelectasis1.01096543
59MP0003950_abnormal_plasma_membrane1.00756213
60MP0010030_abnormal_orbit_morphology1.00046389
61MP0002254_reproductive_system_inflammat0.98752209
62MP0005375_adipose_tissue_phenotype0.98265403
63MP0004036_abnormal_muscle_relaxation0.97930030
64MP0009053_abnormal_anal_canal0.96535086
65MP0004185_abnormal_adipocyte_glucose0.95288545
66MP0009840_abnormal_foam_cell0.94907282
67MP0003385_abnormal_body_wall0.93656360
68MP0005171_absent_coat_pigmentation0.93501272
69MP0002106_abnormal_muscle_physiology0.93072026
70MP0003115_abnormal_respiratory_system0.92117401
71MP0004145_abnormal_muscle_electrophysio0.91827095
72MP0002998_abnormal_bone_remodeling0.91619480
73MP0004084_abnormal_cardiac_muscle0.90388783
74MP0003942_abnormal_urinary_system0.90139243
75MP0004858_abnormal_nervous_system0.89303817
76MP0006138_congestive_heart_failure0.87477530
77MP0000534_abnormal_ureter_morphology0.87176654
78MP0005666_abnormal_adipose_tissue0.86991338
79MP0000163_abnormal_cartilage_morphology0.86817613
80MP0005620_abnormal_muscle_contractility0.86581984
81MP0001348_abnormal_lacrimal_gland0.86294121
82MP0000681_abnormal_thyroid_gland0.85475705
83MP0000428_abnormal_craniofacial_morphol0.83212294
84MP0002282_abnormal_trachea_morphology0.82866535
85MP0000747_muscle_weakness0.82700304
86MP0005330_cardiomyopathy0.81946369
87MP0002115_abnormal_skeleton_extremities0.81694335
88MP0000249_abnormal_blood_vessel0.80109575
89MP0002933_joint_inflammation0.79853153
90MP0001533_abnormal_skeleton_physiology0.78076256
91MP0005197_abnormal_uvea_morphology0.77930525
92MP0000467_abnormal_esophagus_morphology0.77224769
93MP0003828_pulmonary_edema0.76646993
94MP0004484_altered_response_of0.74102186
95MP0002128_abnormal_blood_circulation0.73261490
96MP0000049_abnormal_middle_ear0.72108845
97MP0003448_altered_tumor_morphology0.71897619
98MP0005165_increased_susceptibility_to0.71861792
99MP0000858_altered_metastatic_potential0.71042659
100MP0001175_abnormal_lung_morphology0.70878550
101MP0005076_abnormal_cell_differentiation0.70484205
102MP0001544_abnormal_cardiovascular_syste0.69812007
103MP0005385_cardiovascular_system_phenoty0.69812007
104MP0002932_abnormal_joint_morphology0.68877732
105MP0001614_abnormal_blood_vessel0.68867716
106MP0003795_abnormal_bone_structure0.67170333
107MP0010386_abnormal_urinary_bladder0.66856018
108MP0001299_abnormal_eye_distance/0.66459104
109MP0002269_muscular_atrophy0.65502992
110MP0003075_altered_response_to0.64084422
111MP0001661_extended_life_span0.62959116
112MP0004134_abnormal_chest_morphology0.62608366
113MP0000462_abnormal_digestive_system0.61519870
114MP0002249_abnormal_larynx_morphology0.61194897
115MP0002113_abnormal_skeleton_development0.60113298
116MP0010771_integument_phenotype0.59542623
117MP0003283_abnormal_digestive_organ0.59132206
118MP0009115_abnormal_fat_cell0.58758227
119MP0001915_intracranial_hemorrhage0.58665376
120MP0000538_abnormal_urinary_bladder0.57942120
121MP0000432_abnormal_head_morphology0.57713056
122MP0004510_myositis0.57324150
123MP0005167_abnormal_blood-brain_barrier0.55936830
124MP0005193_abnormal_anterior_eye0.55428700
125MP0010630_abnormal_cardiac_muscle0.54857159
126MP0002925_abnormal_cardiovascular_devel0.53812383
127MP0003329_amyloid_beta_deposits0.52154992
128MP0003186_abnormal_redox_activity0.51998308

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)7.45684586
2Premature rupture of membranes (HP:0001788)6.84808855
3Ankle contracture (HP:0006466)5.67358693
4Type 1 muscle fiber predominance (HP:0003803)5.28544585
5Aortic dissection (HP:0002647)5.21192108
6Increased connective tissue (HP:0009025)5.10914153
7Broad metatarsal (HP:0001783)4.69318662
8Aortic aneurysm (HP:0004942)4.56518636
9Cerebral aneurysm (HP:0004944)4.49625142
10Spinal rigidity (HP:0003306)4.28705553
11Follicular hyperkeratosis (HP:0007502)4.25920090
12Soft skin (HP:0000977)4.15854616
13Atrophic scars (HP:0001075)3.91996565
14Shallow orbits (HP:0000586)3.88568720
15Increased variability in muscle fiber diameter (HP:0003557)3.88284376
16Slender build (HP:0001533)3.77337362
17Wrist flexion contracture (HP:0001239)3.63832430
18Dilatation of the ascending aorta (HP:0005111)3.62192620
19Fragile skin (HP:0001030)3.55610791
20Bladder diverticulum (HP:0000015)3.52031483
21Mildly elevated creatine phosphokinase (HP:0008180)3.49953708
22Abnormality of skeletal muscle fiber size (HP:0012084)3.49784409
23Muscle fiber splitting (HP:0003555)3.42212464
24Neonatal short-limb short stature (HP:0008921)3.34646203
25Mitral valve prolapse (HP:0001634)3.33183674
26Vascular tortuosity (HP:0004948)3.27442259
27Wormian bones (HP:0002645)3.15336226
28Round ear (HP:0100830)3.06823875
29Vertebral compression fractures (HP:0002953)3.04577224
30Abnormality of dentin (HP:0010299)3.03961775
31Cervical subluxation (HP:0003308)3.02275689
32Arterial tortuosity (HP:0005116)3.02055184
33Peritonitis (HP:0002586)2.95722985
34Striae distensae (HP:0001065)2.91345887
35Hyperextensible skin (HP:0000974)2.82822565
36Blue sclerae (HP:0000592)2.76126019
37Short nail (HP:0001799)2.68251560
38Osteolytic defects of the hand bones (HP:0009699)2.59942906
39Osteolytic defects of the phalanges of the hand (HP:0009771)2.59942906
40Spondylolisthesis (HP:0003302)2.59015967
41Biconcave vertebral bodies (HP:0004586)2.54522097
42Hyporeflexia of lower limbs (HP:0002600)2.53216571
43Aneurysm (HP:0002617)2.52274349
44Ulnar bowing (HP:0003031)2.50156998
45Hypoventilation (HP:0002791)2.45400403
46Genu recurvatum (HP:0002816)2.43395819
47Aortic valve stenosis (HP:0001650)2.42792893
48Natal tooth (HP:0000695)2.40832444
49Abnormal delivery (HP:0001787)2.39325179
50Difficulty climbing stairs (HP:0003551)2.39320875
51Elbow flexion contracture (HP:0002987)2.37574922
52Pulmonary artery stenosis (HP:0004415)2.35249698
53Joint laxity (HP:0001388)2.32704000
54Coronal craniosynostosis (HP:0004440)2.24556237
55Distal lower limb amyotrophy (HP:0008944)2.22161515
56Cardiovascular calcification (HP:0011915)2.21655498
57Alopecia of scalp (HP:0002293)2.18706564
58Breech presentation (HP:0001623)2.18680698
59Overgrowth (HP:0001548)2.18570546
60Reduced subcutaneous adipose tissue (HP:0003758)2.18412826
61Right ventricular cardiomyopathy (HP:0011663)2.17989386
62Venous abnormality (HP:0002624)2.14720839
63Delayed cranial suture closure (HP:0000270)2.11024503
64Mild short stature (HP:0003502)2.10924197
65Camptodactyly of toe (HP:0001836)2.10649096
66Myotonia (HP:0002486)2.09550984
67Mitral stenosis (HP:0001718)2.07131665
68Generalized amyotrophy (HP:0003700)2.05932569
69Wide anterior fontanel (HP:0000260)2.03884046
70Ovoid vertebral bodies (HP:0003300)2.02823792
71Redundant skin (HP:0001582)2.02174903
72Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.00080620
73Hypercortisolism (HP:0001578)1.99273042
74Abnormality of the Achilles tendon (HP:0005109)1.95769952
75Limb-girdle muscle weakness (HP:0003325)1.95154799
76Ulnar deviation of the wrist (HP:0003049)1.94764198
77Bowel diverticulosis (HP:0005222)1.93988794
78Acanthosis nigricans (HP:0000956)1.93981528
79Flat cornea (HP:0007720)1.93761496
80Delayed closure of the anterior fontanelle (HP:0001476)1.93748006
81Venous insufficiency (HP:0005293)1.93607334
82Muscle fiber inclusion bodies (HP:0100299)1.92823038
83Ectopia lentis (HP:0001083)1.92543160
84Abnormality of skull ossification (HP:0002703)1.92448526
85Abnormality of the acetabulum (HP:0003170)1.91935654
86Mitral regurgitation (HP:0001653)1.91699921
87Rectal prolapse (HP:0002035)1.90989434
88Protruding ear (HP:0000411)1.90986799
89Narrow nasal bridge (HP:0000446)1.90547072
90Tarsal synostosis (HP:0008368)1.89942798
91Joint stiffness (HP:0001387)1.89683572
92Bronchomalacia (HP:0002780)1.87869428
93Scapular winging (HP:0003691)1.87861160
94Achilles tendon contracture (HP:0001771)1.86680969
95Coxa vara (HP:0002812)1.86602755
96Calcaneovalgus deformity (HP:0001848)1.85925199
97Complement deficiency (HP:0004431)1.85580543
98Disproportionate tall stature (HP:0001519)1.85518046
99Distal arthrogryposis (HP:0005684)1.84837564
100Mesangial abnormality (HP:0001966)1.84515142
101Premature skin wrinkling (HP:0100678)1.83577714
102Thin bony cortex (HP:0002753)1.83282095
103Gastrointestinal dysmotility (HP:0002579)1.83203600
104Aortic regurgitation (HP:0001659)1.83180521
105Glucose intolerance (HP:0000833)1.82756641
106Difficulty running (HP:0009046)1.82009983
107Hyperacusis (HP:0010780)1.79995856
108Long toe (HP:0010511)1.79363419
109Deviation of the hallux (HP:0010051)1.79145102
110Upper limb amyotrophy (HP:0009129)1.77644666
111Distal upper limb amyotrophy (HP:0007149)1.77644666
112Osteopenia (HP:0000938)1.77475374
113Bowed forearm bones (HP:0003956)1.77012240
114Bowing of the arm (HP:0006488)1.77012240
115Short hallux (HP:0010109)1.75226667
116Hallux valgus (HP:0001822)1.74987803
117Entropion (HP:0000621)1.74839045
118Abnormality of the calf musculature (HP:0001430)1.74253689
119Inguinal hernia (HP:0000023)1.73384752
120Thin skin (HP:0000963)1.72727130
121Lower limb amyotrophy (HP:0007210)1.71869235
122Spinal cord compression (HP:0002176)1.71706384
123Osteoarthritis (HP:0002758)1.71136851
124Nonimmune hydrops fetalis (HP:0001790)1.70201802
125Bell-shaped thorax (HP:0001591)1.70042057
126Bradycardia (HP:0001662)1.69505563
127Hand muscle atrophy (HP:0009130)1.69359233
128Distal lower limb muscle weakness (HP:0009053)1.69067945
129Facial diplegia (HP:0001349)1.68662818
130Renal duplication (HP:0000075)1.68051589
131Mesomelia (HP:0003027)1.67763638
132Delayed gross motor development (HP:0002194)1.66837112
133Decreased skull ossification (HP:0004331)1.62959971

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.40765234
2TTN4.13436460
3DDR23.75979190
4MYLK3.16192822
5ERN13.03385969
6PDGFRA2.86713181
7TGFBR22.85598806
8LATS22.53236562
9EPHA22.25071667
10ARAF2.23569692
11RIPK12.15018430
12EPHB22.13667855
13PTK2B1.98101304
14TIE11.96546607
15NME21.95770036
16NEK91.91802676
17FER1.90439765
18DAPK21.82762233
19IRAK31.75511235
20DMPK1.71472978
21BMX1.66970998
22SIK11.59210224
23TRPM71.57318657
24PAK21.49468999
25LIMK11.46093819
26TESK11.45764355
27PKN21.42615237
28ILK1.38090551
29FLT31.31377352
30LMTK21.23923861
31CAMK1D1.20715783
32MAPKAPK31.19012613
33NTRK11.15824656
34PDK21.15492085
35ERBB41.15334645
36MST1R1.14661710
37PIK3CG1.13978147
38DAPK31.13860558
39MAP2K11.13562637
40PTK21.12504684
41PAK41.12386441
42EPHB11.12084713
43PRKD31.08046886
44MET1.07850323
45MAP3K31.06762292
46MOS1.06263286
47LRRK21.03992572
48KSR21.03140299
49PDK31.03128222
50PDK41.03128222
51PAK61.03022811
52PDGFRB1.02895832
53TESK20.99949832
54LATS10.98203713
55ADRBK10.97567156
56PRKD20.97283641
57EEF2K0.94507865
58ROCK10.93904242
59TAOK20.90816282
60PHKG10.88229551
61PHKG20.88229551
62GRK10.88037252
63PTK60.87828070
64MAP2K30.87393140
65SMG10.85426666
66CAMK1G0.83669467
67PIM20.80747677
68CDK80.80393299
69BRAF0.80260176
70DAPK10.79162853
71KIT0.78267361
72PRKCH0.78160364
73MAP3K120.77812241
74ROCK20.76490946
75AKT30.74063027
76RET0.73608408
77PRKG20.73545524
78MAP3K70.72813276
79PLK20.72569396
80PRKD10.72511985
81CSK0.71255909
82EPHA30.70956816
83MAP3K20.66732243
84CAMK2G0.63408443
85TYRO30.63001324
86ICK0.61065353
87MAPK70.60764614
88GRK50.60559486
89GRK70.60108674
90PRPF4B0.59758424
91PAK30.58577020
92TAOK10.57036929
93FGFR10.56645525
94MAP3K60.56404990
95PAK10.54686027
96TBK10.54503059
97RPS6KA20.54331526
98CAMKK10.53802676
99MAPK120.52876343
100CDC42BPA0.51872959
101OBSCN0.49561483
102STK380.49559368
103PIK3CA0.49156115
104SCYL20.49031648
105FGFR20.48322384
106GSK3A0.46989589
107MELK0.46016023
108CAMKK20.45225724
109FGFR40.41811213
110MAP3K10.40639753
111MTOR0.40592122
112NME10.40273236
113SRC0.39830696
114JAK10.36843875
115PDPK10.36672937
116VRK20.36571487
117WNK10.36502059
118NEK20.35844219
119INSR0.35166497
120CASK0.34766282
121MAPKAPK20.34061246
122TYK20.33925828
123MAP3K110.33515739
124STK30.33324901
125ABL20.33303556
126MAP3K130.33017827
127RAF10.32980213
128ERBB30.32734672
129MAP3K80.31699795
130PINK10.31219996
131RPS6KA40.29358065
132NTRK30.27825404
133CAMK2D0.24709373
134ZAP700.23095286
135HIPK20.22516001
136JAK30.20937120

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.99495141
2Focal adhesion_Homo sapiens_hsa045102.80114981
3AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049332.28251244
4Other glycan degradation_Homo sapiens_hsa005112.25035662
5Protein digestion and absorption_Homo sapiens_hsa049742.12836287
6Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.11080918
7Amoebiasis_Homo sapiens_hsa051462.10244288
8Dilated cardiomyopathy_Homo sapiens_hsa054142.08862843
9Regulation of lipolysis in adipocytes_Homo sapiens_hsa049232.00361417
10Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.86864073
11Proteoglycans in cancer_Homo sapiens_hsa052051.74374579
12Malaria_Homo sapiens_hsa051441.56867114
13Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.48532023
14Galactose metabolism_Homo sapiens_hsa000521.46412647
15TGF-beta signaling pathway_Homo sapiens_hsa043501.43965243
16Renin secretion_Homo sapiens_hsa049241.39630425
17Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.39201191
18Adherens junction_Homo sapiens_hsa045201.38246257
19Vascular smooth muscle contraction_Homo sapiens_hsa042701.37892802
20Fatty acid biosynthesis_Homo sapiens_hsa000611.29670689
21Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.28489471
22N-Glycan biosynthesis_Homo sapiens_hsa005101.25242522
23Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.24504618
24PI3K-Akt signaling pathway_Homo sapiens_hsa041511.20911161
25Bladder cancer_Homo sapiens_hsa052191.17793073
26Pentose phosphate pathway_Homo sapiens_hsa000301.16748539
27Sulfur metabolism_Homo sapiens_hsa009201.13180386
28Regulation of actin cytoskeleton_Homo sapiens_hsa048101.12491815
29Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.10683106
30Oxytocin signaling pathway_Homo sapiens_hsa049211.10399882
31Small cell lung cancer_Homo sapiens_hsa052221.08031111
32Tight junction_Homo sapiens_hsa045301.08002924
33Hippo signaling pathway_Homo sapiens_hsa043901.05293556
34Glutathione metabolism_Homo sapiens_hsa004801.04530769
35Caffeine metabolism_Homo sapiens_hsa002321.04052956
36Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.01511400
37Phagosome_Homo sapiens_hsa041451.00022047
38GnRH signaling pathway_Homo sapiens_hsa049120.99376240
39VEGF signaling pathway_Homo sapiens_hsa043700.99364932
40Salivary secretion_Homo sapiens_hsa049700.98094901
41cGMP-PKG signaling pathway_Homo sapiens_hsa040220.96566812
42Adipocytokine signaling pathway_Homo sapiens_hsa049200.96106872
43Platelet activation_Homo sapiens_hsa046110.94730444
44Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.93745242
45Rap1 signaling pathway_Homo sapiens_hsa040150.93466955
46Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.93070990
47Gastric acid secretion_Homo sapiens_hsa049710.93054048
48Prion diseases_Homo sapiens_hsa050200.92711940
49Gap junction_Homo sapiens_hsa045400.91743294
50Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.91446498
51PPAR signaling pathway_Homo sapiens_hsa033200.91228583
52Estrogen signaling pathway_Homo sapiens_hsa049150.89417396
53Thyroid hormone synthesis_Homo sapiens_hsa049180.88059400
54Glioma_Homo sapiens_hsa052140.87723538
55Sulfur relay system_Homo sapiens_hsa041220.85879071
56Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.85552648
57Glycosaminoglycan degradation_Homo sapiens_hsa005310.85438429
58Leukocyte transendothelial migration_Homo sapiens_hsa046700.85101923
59Aldosterone synthesis and secretion_Homo sapiens_hsa049250.84845683
60Viral myocarditis_Homo sapiens_hsa054160.84781402
61Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.84432053
62Insulin signaling pathway_Homo sapiens_hsa049100.84344802
63Toxoplasmosis_Homo sapiens_hsa051450.83090394
64Melanogenesis_Homo sapiens_hsa049160.82037198
65Chronic myeloid leukemia_Homo sapiens_hsa052200.78732848
66Central carbon metabolism in cancer_Homo sapiens_hsa052300.77615987
67Melanoma_Homo sapiens_hsa052180.77379914
68Complement and coagulation cascades_Homo sapiens_hsa046100.77375814
69Vibrio cholerae infection_Homo sapiens_hsa051100.76267265
70Rheumatoid arthritis_Homo sapiens_hsa053230.75858226
71Longevity regulating pathway - mammal_Homo sapiens_hsa042110.75481078
72Insulin resistance_Homo sapiens_hsa049310.74363798
73Salmonella infection_Homo sapiens_hsa051320.73541493
74p53 signaling pathway_Homo sapiens_hsa041150.73332274
75Hedgehog signaling pathway_Homo sapiens_hsa043400.71674136
76Axon guidance_Homo sapiens_hsa043600.70865898
77Basal cell carcinoma_Homo sapiens_hsa052170.70739586
78Pertussis_Homo sapiens_hsa051330.69311135
79Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.68849903
80Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.68847866
81Synaptic vesicle cycle_Homo sapiens_hsa047210.68310118
82Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.67891001
83cAMP signaling pathway_Homo sapiens_hsa040240.67339082
84AMPK signaling pathway_Homo sapiens_hsa041520.67254144
85Ras signaling pathway_Homo sapiens_hsa040140.67003449
86Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.65688253
87Pancreatic cancer_Homo sapiens_hsa052120.65608603
88Circadian entrainment_Homo sapiens_hsa047130.64968082
89Pathways in cancer_Homo sapiens_hsa052000.64491010
90Calcium signaling pathway_Homo sapiens_hsa040200.64324067
91Apoptosis_Homo sapiens_hsa042100.63216402
92Lysosome_Homo sapiens_hsa041420.63058984
93Fructose and mannose metabolism_Homo sapiens_hsa000510.63006438
94HIF-1 signaling pathway_Homo sapiens_hsa040660.62677359
95Glucagon signaling pathway_Homo sapiens_hsa049220.62580870
96Renin-angiotensin system_Homo sapiens_hsa046140.62328371
97Phospholipase D signaling pathway_Homo sapiens_hsa040720.60780611
98MAPK signaling pathway_Homo sapiens_hsa040100.60590836
99Folate biosynthesis_Homo sapiens_hsa007900.60007701
100Endocytosis_Homo sapiens_hsa041440.59889288
101Prostate cancer_Homo sapiens_hsa052150.59776598
102TNF signaling pathway_Homo sapiens_hsa046680.59377652
103Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58262853
1042-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.58163834
105MicroRNAs in cancer_Homo sapiens_hsa052060.56402884
106Long-term potentiation_Homo sapiens_hsa047200.56338793
107SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55954016
108Neurotrophin signaling pathway_Homo sapiens_hsa047220.55575148
109Amphetamine addiction_Homo sapiens_hsa050310.54022811
110Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.53952751
111mTOR signaling pathway_Homo sapiens_hsa041500.53653187
112Renal cell carcinoma_Homo sapiens_hsa052110.52216024
113Wnt signaling pathway_Homo sapiens_hsa043100.51882349
114HTLV-I infection_Homo sapiens_hsa051660.50506100
115Tuberculosis_Homo sapiens_hsa051520.50236661
116Biosynthesis of amino acids_Homo sapiens_hsa012300.49850964
117Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.48033486
118Thyroid cancer_Homo sapiens_hsa052160.47953643
119Shigellosis_Homo sapiens_hsa051310.47304621
120Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.46997313
121Cyanoamino acid metabolism_Homo sapiens_hsa004600.45151360
122Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.44703277
123Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.40723499
124Sphingolipid metabolism_Homo sapiens_hsa006000.39739664
125Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.37996602
126Notch signaling pathway_Homo sapiens_hsa043300.37761842
127Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.33368994
128Thyroid hormone signaling pathway_Homo sapiens_hsa049190.32956095
129Hepatitis C_Homo sapiens_hsa051600.32785199
130Hepatitis B_Homo sapiens_hsa051610.31907679
131Mineral absorption_Homo sapiens_hsa049780.30873617
132Vitamin B6 metabolism_Homo sapiens_hsa007500.29178062

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