IGHG1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous antigen (GO:0019883)8.66931756
2B cell receptor signaling pathway (GO:0050853)8.10324844
3regulation of B cell receptor signaling pathway (GO:0050855)7.55947105
4cellular response to zinc ion (GO:0071294)7.49246453
5* complement activation, classical pathway (GO:0006958)6.94767013
6positive regulation of respiratory burst (GO:0060267)5.94100409
7negative regulation of gene silencing (GO:0060969)5.92703484
8glomerular filtration (GO:0003094)5.45242524
9* complement activation (GO:0006956)5.35214825
10positive thymic T cell selection (GO:0045059)5.02887484
11renal filtration (GO:0097205)4.91287578
12somatic diversification of immunoglobulins (GO:0016445)4.88676191
13regulation of germinal center formation (GO:0002634)4.85892799
14type I interferon signaling pathway (GO:0060337)4.84242375
15cellular response to type I interferon (GO:0071357)4.84242375
16response to type I interferon (GO:0034340)4.83696347
17antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.79584748
18antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.79584748
19negative regulation of B cell apoptotic process (GO:0002903)4.77477525
20detection of bacterium (GO:0016045)4.69411852
21antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.68883508
22regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.58108380
23* immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:00024.57120784
24* Fc-gamma receptor signaling pathway (GO:0038094)4.57120784
25* Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096)4.57120784
26B cell proliferation (GO:0042100)4.56061457
27negative thymic T cell selection (GO:0045060)4.52137815
28regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.52096960
29regulation of respiratory burst (GO:0060263)4.52019725
30* Fc receptor mediated stimulatory signaling pathway (GO:0002431)4.49846470
31regulation of B cell apoptotic process (GO:0002902)4.45923340
32antimicrobial humoral response (GO:0019730)4.45173593
33regulation of antigen processing and presentation (GO:0002577)4.44760759
34regulation of chromatin silencing (GO:0031935)4.43008045
35antibacterial humoral response (GO:0019731)4.39641423
36detection of other organism (GO:0098543)4.39604970
37DNA demethylation (GO:0080111)4.39427709
38NIK/NF-kappaB signaling (GO:0038061)4.38801345
39regulation of B cell differentiation (GO:0045577)4.36570264
40somatic diversification of immunoglobulins involved in immune response (GO:0002208)4.35110482
41isotype switching (GO:0045190)4.35110482
42somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)4.35110482
43germinal center formation (GO:0002467)4.19014154
44positive regulation of gamma-delta T cell activation (GO:0046645)4.18902425
45positive regulation of gene expression, epigenetic (GO:0045815)4.18750585
46negative T cell selection (GO:0043383)4.13060754
47regulation of B cell proliferation (GO:0030888)4.12137640
48negative regulation of cell killing (GO:0031342)3.98989343
49negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.98989343
50Arp2/3 complex-mediated actin nucleation (GO:0034314)3.94499382
51regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.92932028
52positive regulation of macrophage cytokine production (GO:0060907)3.90691566
53B cell activation involved in immune response (GO:0002312)3.87083070
54regulation of dendritic cell antigen processing and presentation (GO:0002604)3.77279666
55* immune response-activating cell surface receptor signaling pathway (GO:0002429)3.77065019
56cellular response to interferon-gamma (GO:0071346)3.77055138
57* humoral immune response (GO:0006959)3.75525957
58myeloid dendritic cell differentiation (GO:0043011)3.73596425
59positive regulation of B cell differentiation (GO:0045579)3.72470585
60regulation of cellular extravasation (GO:0002691)3.70740323
61thymic T cell selection (GO:0045061)3.70516721
62positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.67791515
63immunoglobulin mediated immune response (GO:0016064)3.63915389
64positive regulation of Cdc42 GTPase activity (GO:0043089)3.59395419
65positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.58855749
66pyrimidine nucleoside catabolic process (GO:0046135)3.57815083
67B cell homeostasis (GO:0001782)3.53913183
68positive regulation of B cell proliferation (GO:0030890)3.53514488
69somatic recombination of immunoglobulin gene segments (GO:0016447)3.51609342
70response to interferon-gamma (GO:0034341)3.49741763
71myeloid dendritic cell activation (GO:0001773)3.48209294
72somatic diversification of immune receptors (GO:0002200)3.46616452
73negative regulation of B cell proliferation (GO:0030889)3.42751124
74positive T cell selection (GO:0043368)3.42566748
75retina homeostasis (GO:0001895)3.40893175
76T-helper 1 type immune response (GO:0042088)3.40735369
77regulation of gamma-delta T cell differentiation (GO:0045586)3.39607797
78B cell mediated immunity (GO:0019724)3.39513694
79telomere maintenance via semi-conservative replication (GO:0032201)3.38184861
80surfactant homeostasis (GO:0043129)3.36381720
81chaperone mediated protein folding requiring cofactor (GO:0051085)3.34990622
82positive regulation of lamellipodium assembly (GO:0010592)3.32615063
83* protein activation cascade (GO:0072376)3.31958847
84positive regulation of antigen processing and presentation (GO:0002579)3.31262784
85regulation of glucose import in response to insulin stimulus (GO:2001273)3.30828916
86B cell activation (GO:0042113)3.28262840
87CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.25687909
88negative regulation of immunoglobulin mediated immune response (GO:0002890)3.24819303
89negative regulation of B cell mediated immunity (GO:0002713)3.24819303
90mature B cell differentiation (GO:0002335)3.24718702
91antigen receptor-mediated signaling pathway (GO:0050851)3.24542313
92DNA dealkylation (GO:0035510)3.24173224
93detection of external biotic stimulus (GO:0098581)3.23211796
94regulation of type I interferon-mediated signaling pathway (GO:0060338)3.22568968
95negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.22256276
96DNA strand elongation involved in DNA replication (GO:0006271)3.20775521
97endothelial tube morphogenesis (GO:0061154)3.17935006
98morphogenesis of an endothelium (GO:0003159)3.17935006
99positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.14123655
100positive regulation of Rap GTPase activity (GO:0032854)3.11430795
101mature B cell differentiation involved in immune response (GO:0002313)3.09839986
102negative regulation of phagocytosis (GO:0050765)3.02812516
103nucleotide-excision repair, DNA gap filling (GO:0006297)3.02099113
104regulation of gamma-delta T cell activation (GO:0046643)3.01411846
105positive regulation of protein homooligomerization (GO:0032464)2.99194184
106T cell selection (GO:0045058)2.98738512
107DNA strand elongation (GO:0022616)2.98704308
108regulation of B cell activation (GO:0050864)2.98513756
109regulation of T-helper 1 cell differentiation (GO:0045625)2.95582377
110natural killer cell mediated cytotoxicity (GO:0042267)2.95497035
111natural killer cell mediated immunity (GO:0002228)2.95497035
112positive regulation by symbiont of host defense response (GO:0052509)2.94808868
113modulation by symbiont of host defense response (GO:0052031)2.94808868
114modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.94808868
115modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.94808868
116positive regulation by organism of defense response of other organism involved in symbiotic interact2.94808868
117modulation by symbiont of host immune response (GO:0052553)2.94808868
118positive regulation of granulocyte chemotaxis (GO:0071624)2.92416897
119histamine secretion (GO:0001821)2.89439381
120positive regulation of B cell activation (GO:0050871)2.88453586
121lymphocyte homeostasis (GO:0002260)2.87588472
122response to interleukin-15 (GO:0070672)2.87017176
123regulation of interferon-beta biosynthetic process (GO:0045357)2.86394224
124positive regulation of lamellipodium organization (GO:1902745)2.85053728
125positive regulation of type 2 immune response (GO:0002830)2.84003763
126telomere maintenance via recombination (GO:0000722)2.83985118
127interferon-gamma-mediated signaling pathway (GO:0060333)2.82137608
128response to interferon-beta (GO:0035456)2.80476026
129positive regulation of neutrophil migration (GO:1902624)2.78889472
130positive regulation of neutrophil chemotaxis (GO:0090023)2.78889472
131T cell costimulation (GO:0031295)2.78107453
132actin nucleation (GO:0045010)2.76169050
133dendritic cell differentiation (GO:0097028)2.75644227
134production of molecular mediator of immune response (GO:0002440)2.75199893
135mast cell activation (GO:0045576)2.74810546
136adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.74531561
137* immune response-activating signal transduction (GO:0002757)2.74165608
138JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.73774138
139regulation of T cell migration (GO:2000404)2.73504431
140regulation of T cell tolerance induction (GO:0002664)2.71435842
141positive regulation of pseudopodium assembly (GO:0031274)2.71317549
142regulation of T cell mediated cytotoxicity (GO:0001914)2.70716033
143lymphocyte costimulation (GO:0031294)2.70532418
144regulation of macrophage cytokine production (GO:0010935)2.70175159
145detection of biotic stimulus (GO:0009595)2.69408629
146dendritic cell chemotaxis (GO:0002407)2.68924357
147* activation of immune response (GO:0002253)2.66926664
148defense response to protozoan (GO:0042832)2.66651332
149positive regulation of T cell migration (GO:2000406)2.66222630
150negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.65605013
151negative regulation of bone resorption (GO:0045779)2.65533667
152regulation of lymphocyte migration (GO:2000401)2.64666408
153negative regulation of innate immune response (GO:0045824)2.61321112
154T cell migration (GO:0072678)2.58839480
155positive regulation of T cell mediated cytotoxicity (GO:0001916)2.57604317
156positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.55065114
157positive regulation of lymphocyte migration (GO:2000403)2.53076419
158response to interferon-alpha (GO:0035455)2.49412437
159cytidine metabolic process (GO:0046087)15.0822121
160cytidine catabolic process (GO:0006216)15.0822121
161cytidine deamination (GO:0009972)15.0822121
162pyrimidine ribonucleoside catabolic process (GO:0046133)11.5198582
163somatic diversification of immune receptors via somatic mutation (GO:0002566)11.0591777
164somatic hypermutation of immunoglobulin genes (GO:0016446)11.0591777

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human7.53587092
2E2F7_22180533_ChIP-Seq_HELA_Human6.91093364
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.94623747
4TP63_17297297_ChIP-ChIP_HaCaT_Human4.73250957
5MYC_22102868_ChIP-Seq_BL_Human4.58062588
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.53574114
7IRF8_21731497_ChIP-ChIP_J774_Mouse3.91145899
8SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.89653756
9FOXM1_23109430_ChIP-Seq_U2OS_Human3.49577253
10STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.26217806
11EGR1_19374776_ChIP-ChIP_THP-1_Human3.18213460
12E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human3.02034816
13IRF8_27001747_Chip-Seq_BMDM_Mouse2.67759047
14CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.55230371
15MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.53782902
16VDR_21846776_ChIP-Seq_THP-1_Human2.53353682
17MAF_26560356_Chip-Seq_TH1_Human2.35349821
18RUNX_20019798_ChIP-Seq_JUKART_Human2.22711703
19BP1_19119308_ChIP-ChIP_Hs578T_Human2.22193685
20NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.20710942
21MYB_26560356_Chip-Seq_TH2_Human2.17945299
22GATA1_22025678_ChIP-Seq_K562_Human2.17849227
23IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.16507353
24NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.09378265
25MYB_26560356_Chip-Seq_TH1_Human2.06607024
26FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.99076612
27VDR_24763502_ChIP-Seq_THP-1_Human1.96141117
28UTX_26944678_Chip-Seq_JUKART_Human1.94025152
29STAT4_19710469_ChIP-ChIP_TH1__Mouse1.85801255
30NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.76661427
31EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.75368174
32SPI1_23547873_ChIP-Seq_NB4_Human1.73871257
33STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.72252623
34SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.72209516
35SPI1_23127762_ChIP-Seq_K562_Human1.70259375
36* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.66402640
37E2F4_17652178_ChIP-ChIP_JURKAT_Human1.57380660
38SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.57033151
39TRIM28_21343339_ChIP-Seq_HEK293_Human1.51775301
40MAF_26560356_Chip-Seq_TH2_Human1.50522419
41TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.48229295
42TCF7_22412390_ChIP-Seq_EML_Mouse1.45143831
43STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.43317504
44GATA3_27048872_Chip-Seq_THYMUS_Human1.42453031
45RARG_19884340_ChIP-ChIP_MEFs_Mouse1.38387503
46RUNX1_22412390_ChIP-Seq_EML_Mouse1.37995055
47FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.36771090
48CDX2_20551321_ChIP-Seq_CACO-2_Human1.36755247
49ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.36234593
50NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.33591228
51SCL_19346495_ChIP-Seq_HPC-7_Human1.32813676
52MYB_21317192_ChIP-Seq_ERMYB_Mouse1.31189492
53KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.30949036
54AR_21909140_ChIP-Seq_LNCAP_Human1.30577245
55CIITA_25753668_ChIP-Seq_RAJI_Human1.30506999
56KDM2B_26808549_Chip-Seq_SUP-B15_Human1.29809579
57TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.29694622
58PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.28501072
59RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.28488477
60P63_26484246_Chip-Seq_KERATINOCYTES_Human1.25163622
61KDM2B_26808549_Chip-Seq_DND41_Human1.24823832
62BRD4_27068464_Chip-Seq_AML-cells_Mouse1.23696217
63SOX2_27498859_Chip-Seq_STOMACH_Mouse1.23599842
64RACK7_27058665_Chip-Seq_MCF-7_Human1.22946364
65GATA2_22383799_ChIP-Seq_G1ME_Mouse1.22647687
66ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.19036260
67SMAD_19615063_ChIP-ChIP_OVARY_Human1.17107176
68VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.16659742
69FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.16635291
70ELK3_25401928_ChIP-Seq_HUVEC_Human1.14771024
71CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.13593788
72PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.13564238
73TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13384220
74PU.1_20513432_ChIP-Seq_Bcells_Mouse1.12155754
75E2F1_21310950_ChIP-Seq_MCF-7_Human1.11940425
76BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.11042276
77GATA1_22383799_ChIP-Seq_G1ME_Mouse1.10344578
78E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.09838317
79BCOR_27268052_Chip-Seq_Bcells_Human1.08964759
80IKZF1_21737484_ChIP-ChIP_HCT116_Human1.08511624
81THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.07940269
82MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.05163115
83ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.04596535
84STAT6_21828071_ChIP-Seq_BEAS2B_Human1.01150540
85ELF1_17652178_ChIP-ChIP_JURKAT_Human1.00861607
86FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.00019493
87SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.99912075
88KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.99533138
89SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.98681760
90LXR_22292898_ChIP-Seq_THP-1_Human0.96767199
91KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.95305371
92ESR2_21235772_ChIP-Seq_MCF-7_Human0.94942142
93EGR1_23403033_ChIP-Seq_LIVER_Mouse0.93850342
94GATA3_26560356_Chip-Seq_TH2_Human0.93809112
95CLOCK_20551151_ChIP-Seq_293T_Human0.93409303
96CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.92692279
97VDR_24787735_ChIP-Seq_THP-1_Human0.92691470
98EGR1_19032775_ChIP-ChIP_M12_Human0.92321449
99MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.92004128
100TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.91483865
101DNAJC2_21179169_ChIP-ChIP_NT2_Human0.90437235
102SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90308709
103PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90176442
104SOX2_20726797_ChIP-Seq_SW620_Human0.89364592
105TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.89121434
106FOXP3_21729870_ChIP-Seq_TREG_Human0.88749686
107HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.87933091
108GATA1_19941827_ChIP-Seq_MEL_Mouse0.87891597
109P300_27268052_Chip-Seq_Bcells_Human0.87208354
110GATA6_25053715_ChIP-Seq_YYC3_Human0.86436183
111SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.85482209
112RUNX1_27514584_Chip-Seq_MCF-7_Human0.85021486
113CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.84834428
114GATA3_26560356_Chip-Seq_TH1_Human0.84474495
115KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.84431411
116RXR_22158963_ChIP-Seq_LIVER_Mouse0.84296010
117PPARA_22158963_ChIP-Seq_LIVER_Mouse0.84081371
118SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.83801553
119BCL6_27268052_Chip-Seq_Bcells_Human0.83294166
120TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.82751941
121SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.81595395
122KDM5A_27292631_Chip-Seq_BREAST_Human0.81130252
123CTCF_26484167_Chip-Seq_Bcells_Mouse0.78620583
124SMRT_27268052_Chip-Seq_Bcells_Human0.77252744
125GATA1_19941826_ChIP-Seq_K562_Human0.76720849
126CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.76417276
127HOXB4_20404135_ChIP-ChIP_EML_Mouse0.76319927
128LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.71926200
129CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.71671437
130CREB1_15753290_ChIP-ChIP_HEK293T_Human0.71298794
131NCOR1_26117541_ChIP-Seq_K562_Human0.71132855
132MYC_19079543_ChIP-ChIP_MESCs_Mouse0.69464000
133PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.69134709
134RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.68862951
135Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.64718517

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation6.26891242
2* MP0001800_abnormal_humoral_immune4.75357950
3MP0001790_abnormal_immune_system4.62621923
4MP0005387_immune_system_phenotype4.62621923
5MP0003303_peritoneal_inflammation4.08184113
6MP0000685_abnormal_immune_system4.03662429
7* MP0002452_abnormal_antigen_presenting3.57124203
8MP0003724_increased_susceptibility_to3.51629275
9MP0005671_abnormal_response_to3.32581613
10MP0005000_abnormal_immune_tolerance3.01543793
11* MP0002723_abnormal_immune_serum2.88970270
12* MP0002420_abnormal_adaptive_immunity2.87714315
13MP0004510_myositis2.85847553
14* MP0001819_abnormal_immune_cell2.77999454
15* MP0002398_abnormal_bone_marrow2.64513886
16MP0000013_abnormal_adipose_tissue2.52783871
17* MP0000716_abnormal_immune_system2.42362399
18MP0000689_abnormal_spleen_morphology2.38467934
19MP0002148_abnormal_hypersensitivity_rea2.37497753
20MP0003300_gastrointestinal_ulcer2.12943197
21MP0005275_abnormal_skin_tensile2.11891465
22MP0010234_abnormal_vibrissa_follicle2.07465244
23MP0003763_abnormal_thymus_physiology2.06481190
24MP0005025_abnormal_response_to2.01493445
25* MP0002429_abnormal_blood_cell1.99999362
26MP0010094_abnormal_chromosome_stability1.98296878
27MP0002722_abnormal_immune_system1.94691246
28MP0001853_heart_inflammation1.84288499
29MP0005310_abnormal_salivary_gland1.84251836
30MP0002933_joint_inflammation1.81864487
31MP0001879_abnormal_lymphatic_vessel1.76914529
32MP0002419_abnormal_innate_immunity1.74173040
33MP0001533_abnormal_skeleton_physiology1.69391368
34MP0003183_abnormal_peptide_metabolism1.64456747
35MP0004264_abnormal_extraembryonic_tissu1.63761270
36MP0009785_altered_susceptibility_to1.61784618
37MP0002796_impaired_skin_barrier1.61077947
38MP0001845_abnormal_inflammatory_respons1.56403620
39MP0002166_altered_tumor_susceptibility1.54492712
40MP0002405_respiratory_system_inflammati1.54354119
41MP0003436_decreased_susceptibility_to1.49870845
42MP0008438_abnormal_cutaneous_collagen1.37952880
43MP0000003_abnormal_adipose_tissue1.36892814
44MP0004947_skin_inflammation1.33353255
45MP0003453_abnormal_keratinocyte_physiol1.33130062
46MP0000858_altered_metastatic_potential1.25632764
47MP0002254_reproductive_system_inflammat1.25372360
48MP0004782_abnormal_surfactant_physiolog1.23211140
49MP0001958_emphysema1.22951671
50MP0002019_abnormal_tumor_incidence1.21120729
51MP0010352_gastrointestinal_tract_polyps1.17025956
52MP0005503_abnormal_tendon_morphology1.16300554
53MP0000703_abnormal_thymus_morphology1.15556915
54MP0002136_abnormal_kidney_physiology1.14859014
55MP0000465_gastrointestinal_hemorrhage1.11750218
56MP0010155_abnormal_intestine_physiology1.10830685
57MP0005464_abnormal_platelet_physiology1.10322547
58MP0003448_altered_tumor_morphology1.10245348
59MP0002138_abnormal_hepatobiliary_system1.09015081
60MP0002396_abnormal_hematopoietic_system1.07483108
61MP0003077_abnormal_cell_cycle1.07392604
62MP0002006_tumorigenesis1.02027006
63MP0003866_abnormal_defecation1.01745347
64MP0001851_eye_inflammation1.01404399
65MP0003075_altered_response_to1.01351124
66MP0003693_abnormal_embryo_hatching1.00249164
67MP0001216_abnormal_epidermal_layer1.00179731
68MP0002998_abnormal_bone_remodeling0.99347807
69MP0009840_abnormal_foam_cell0.98989833
70MP0002876_abnormal_thyroid_physiology0.98980857
71MP0004957_abnormal_blastocyst_morpholog0.98929042
72MP0008057_abnormal_DNA_replication0.97205326
73MP0001663_abnormal_digestive_system0.96387787
74MP0000490_abnormal_crypts_of0.95924011
75MP0000343_altered_response_to0.95222413
76MP0004858_abnormal_nervous_system0.93202130
77MP0008260_abnormal_autophagy0.92882520
78MP0000604_amyloidosis0.92164590
79MP0003828_pulmonary_edema0.90440833
80MP0009333_abnormal_splenocyte_physiolog0.89608543
81MP0005390_skeleton_phenotype0.87181086
82MP0001191_abnormal_skin_condition0.86419974
83MP0001873_stomach_inflammation0.86084576
84MP0008469_abnormal_protein_level0.82519406
85MP0001730_embryonic_growth_arrest0.81529547
86MP0006054_spinal_hemorrhage0.81167005
87MP0002060_abnormal_skin_morphology0.80156449
88MP0008004_abnormal_stomach_pH0.79149137
89MP0003279_aneurysm0.76893653
90MP0001666_abnormal_nutrient_absorption0.76844078
91MP0008961_abnormal_basal_metabolism0.76499411
92MP0002277_abnormal_respiratory_mucosa0.75464845
93MP0009931_abnormal_skin_appearance0.75312741
94MP0003566_abnormal_cell_adhesion0.74726365
95MP0005584_abnormal_enzyme/coenzyme_acti0.74662706
96MP0005058_abnormal_lysosome_morphology0.74542260
97MP0000477_abnormal_intestine_morphology0.73518035
98MP0003111_abnormal_nucleus_morphology0.71352264
99MP0009643_abnormal_urine_homeostasis0.70956750
100MP0000609_abnormal_liver_physiology0.70478167
101MP0005501_abnormal_skin_physiology0.70263637
102MP0000249_abnormal_blood_vessel0.69884636
103MP0005023_abnormal_wound_healing0.69840336
104MP0006082_CNS_inflammation0.69490256
105MP0003795_abnormal_bone_structure0.69136748
106MP0004036_abnormal_muscle_relaxation0.68958560
107MP0004808_abnormal_hematopoietic_stem0.68654144
108MP0005451_abnormal_body_composition0.68003452
109MP0010678_abnormal_skin_adnexa0.67946537
110MP0005164_abnormal_response_to0.67534733
111MP0001348_abnormal_lacrimal_gland0.66806684
112MP0009278_abnormal_bone_marrow0.66385484
113MP0003091_abnormal_cell_migration0.65266849
114MP0005165_increased_susceptibility_to0.64646575
115MP0003191_abnormal_cellular_cholesterol0.64013567
116MP0000350_abnormal_cell_proliferation0.63935567
117MP0003868_abnormal_feces_composition0.63764638
118MP0003045_fibrosis0.63697053
119MP0002133_abnormal_respiratory_system0.63012700
120MP0005388_respiratory_system_phenotype0.63012700
121MP0003705_abnormal_hypodermis_morpholog0.59822797
122MP0002083_premature_death0.58952194
123MP0009764_decreased_sensitivity_to0.58732357
124MP0010368_abnormal_lymphatic_system0.57061762
125MP0002168_other_aberrant_phenotype0.56987847
126MP0009763_increased_sensitivity_to0.56987133
127MP0002139_abnormal_hepatobiliary_system0.55490413
128MP0008995_early_reproductive_senescence0.54113713
129MP0002163_abnormal_gland_morphology0.53361874
130MP0006036_abnormal_mitochondrial_physio0.52800768
131MP0005076_abnormal_cell_differentiation0.52677244
132MP0005375_adipose_tissue_phenotype0.52029026
133MP0000681_abnormal_thyroid_gland0.51917931
134MP0002693_abnormal_pancreas_physiology0.49394091
135MP0000598_abnormal_liver_morphology0.49328250
136MP0005166_decreased_susceptibility_to0.46897788
137MP0008875_abnormal_xenobiotic_pharmacok0.46370181
138MP0005360_urolithiasis0.45760068
139MP0000313_abnormal_cell_death0.45405355
140MP0002135_abnormal_kidney_morphology0.44472172
141MP0008874_decreased_physiological_sensi0.44442229

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)9.86094838
2Gastrointestinal stroma tumor (HP:0100723)9.42080603
3Recurrent sinusitis (HP:0011108)7.53995216
4Recurrent bronchitis (HP:0002837)6.87359322
5Cellulitis (HP:0100658)6.32498764
6Colitis (HP:0002583)6.13843188
7IgA deficiency (HP:0002720)5.64090181
8Recurrent lower respiratory tract infections (HP:0002783)5.60316502
9Emphysema (HP:0002097)5.50926316
10Lymphopenia (HP:0001888)5.44894528
11Systemic lupus erythematosus (HP:0002725)5.42883445
12Abnormality of cells of the lymphoid lineage (HP:0012140)5.42470357
13Interstitial pulmonary disease (HP:0006530)5.39086704
14Verrucae (HP:0200043)5.14189313
15Papilloma (HP:0012740)5.14189313
16Abnormal delayed hypersensitivity skin test (HP:0002963)5.13204495
17Chronic sinusitis (HP:0011109)5.06590437
18Recurrent pneumonia (HP:0006532)4.78177148
19IgM deficiency (HP:0002850)4.78064466
20Inflammation of the large intestine (HP:0002037)4.70373591
21Bronchitis (HP:0012387)4.67724304
22IgG deficiency (HP:0004315)4.55940978
23Gastrointestinal inflammation (HP:0004386)4.54539938
24Recurrent viral infections (HP:0004429)4.51899417
25Vasculitis (HP:0002633)4.34758134
26Restrictive lung disease (HP:0002091)4.32686655
27Chronic otitis media (HP:0000389)4.23869685
28Autoimmune thrombocytopenia (HP:0001973)4.22672398
29Abnormality of macrophages (HP:0004311)4.20358024
30Panhypogammaglobulinemia (HP:0003139)4.17074242
31Meningitis (HP:0001287)4.14861457
32Prostate neoplasm (HP:0100787)4.06690119
33Osteomyelitis (HP:0002754)4.05045495
34Malnutrition (HP:0004395)4.02657631
35Recurrent otitis media (HP:0000403)3.75396319
36B lymphocytopenia (HP:0010976)3.75006068
37Abnormality of B cell number (HP:0010975)3.75006068
38Abnormality of complement system (HP:0005339)3.57784261
39Abnormality of T cell physiology (HP:0011840)3.51783781
40Abnormality of the prostate (HP:0008775)3.45219126
41Glomerulonephritis (HP:0000099)3.41244507
42Alopecia of scalp (HP:0002293)3.33637662
43Complement deficiency (HP:0004431)3.22850565
44Viral hepatitis (HP:0006562)3.22269236
45Recurrent cutaneous fungal infections (HP:0011370)3.19663497
46Chronic mucocutaneous candidiasis (HP:0002728)3.19663497
47Premature loss of primary teeth (HP:0006323)3.11058949
48Gastrointestinal infarctions (HP:0005244)3.09094299
49Sepsis (HP:0100806)3.02332320
50Leukopenia (HP:0001882)3.01106415
51Recurrent fungal infections (HP:0002841)2.98305480
52Nephritis (HP:0000123)2.95861078
53Thyroiditis (HP:0100646)2.89890248
54Abnormality of T cells (HP:0002843)2.82750335
55Lymphoma (HP:0002665)2.71685349
56Skin rash (HP:0000988)2.70768396
57Abnormality of the nasal mucosa (HP:0000433)2.66934589
58Recurrent abscess formation (HP:0002722)2.63835763
59Obstructive lung disease (HP:0006536)2.62754756
60Chronic obstructive pulmonary disease (HP:0006510)2.62754756
61Eczematoid dermatitis (HP:0000976)2.61659856
62Gingivitis (HP:0000230)2.60682788
63Recurrent bacterial skin infections (HP:0005406)2.56556511
64Recurrent skin infections (HP:0001581)2.54780842
65Hemoptysis (HP:0002105)2.47778078
66Myositis (HP:0100614)2.41013662
67Nasal polyposis (HP:0100582)2.39866702
68Thick nail (HP:0001805)2.37795445
69Orchitis (HP:0100796)2.34852389
70Recurrent gram-negative bacterial infections (HP:0005420)2.31789043
71Papilledema (HP:0001085)2.30787136
72Spontaneous hematomas (HP:0007420)2.29598049
73Small epiphyses (HP:0010585)2.28286230
74Autoimmune hemolytic anemia (HP:0001890)2.26984198
75Abnormality of T cell number (HP:0011839)2.25663094
76Erythema (HP:0010783)2.23275096
77Abnormality of small intestinal villus morphology (HP:0011472)2.22269014
78Villous atrophy (HP:0011473)2.22269014
79Abnormality of nail color (HP:0100643)2.22146089
80Increased IgE level (HP:0003212)2.20313093
81Chest pain (HP:0100749)2.19166794
82Arthralgia (HP:0002829)2.17365923
83Hematochezia (HP:0002573)2.15250637
84Onycholysis (HP:0001806)2.13524206
85Increased IgM level (HP:0003496)2.11151725
86Abnormality of male internal genitalia (HP:0000022)2.10944284
87Plantar hyperkeratosis (HP:0007556)2.10406883
88Skin ulcer (HP:0200042)2.10243555
89Purpura (HP:0000979)2.10016112
90Retrobulbar optic neuritis (HP:0100654)2.07969121
91Optic neuritis (HP:0100653)2.07969121
92Mucosal telangiectasiae (HP:0100579)2.07883376
93Hepatitis (HP:0012115)2.07588323
94Abnormality of the peritoneum (HP:0002585)2.05446796
95Mediastinal lymphadenopathy (HP:0100721)2.04000323
96Limb hypertonia (HP:0002509)2.02758768
97Abnormality of the pleura (HP:0002103)2.01138640
98Encephalitis (HP:0002383)2.01006571
99Polygenic inheritance (HP:0010982)2.00677961
100Ridged nail (HP:0001807)2.00323884
101Neutropenia (HP:0001875)2.00156158
102Hypermelanotic macule (HP:0001034)1.99309941
103Eosinophilia (HP:0001880)1.98198476
104Palmoplantar hyperkeratosis (HP:0000972)1.97927894
105Abnormal hair laboratory examination (HP:0003328)1.95007127
106Elevated erythrocyte sedimentation rate (HP:0003565)1.93698411
107Combined immunodeficiency (HP:0005387)1.92883629
108Bronchiectasis (HP:0002110)1.92544730
109Dehydration (HP:0001944)1.91300890
110Xerostomia (HP:0000217)1.89402033
111Keratoconjunctivitis sicca (HP:0001097)1.87166272
112Polycythemia (HP:0001901)1.85276747
113Hypoplasia of the capital femoral epiphysis (HP:0003090)1.77008050
114Vertebral arch anomaly (HP:0008438)1.76502085
115Pustule (HP:0200039)1.74812469
116Hypergammaglobulinemia (HP:0010702)1.74654190
117Granulocytopenia (HP:0001913)1.72529018
118Thrombocytosis (HP:0001894)1.71472454
119Hyperactive renin-angiotensin system (HP:0000841)1.71270658
120T lymphocytopenia (HP:0005403)1.68700989
121Abnormality of the fingertips (HP:0001211)1.65015047
122Mitral stenosis (HP:0001718)1.64532434
123Hypochromic anemia (HP:0001931)1.62773246
124Chronic diarrhea (HP:0002028)1.58338507
125Deep venous thrombosis (HP:0002625)1.55602703
126Leukocytosis (HP:0001974)1.53501311
127Ulnar bowing (HP:0003031)1.51268410
128Camptodactyly of toe (HP:0001836)1.49426444
129Microcytic anemia (HP:0001935)1.48968867
130Abnormality of eosinophils (HP:0001879)1.47816081
131Irregular vertebral endplates (HP:0003301)1.47155008
132Urticaria (HP:0001025)1.46940575
133Acrocyanosis (HP:0001063)1.46780456
134Pulmonary infiltrates (HP:0002113)1.46040610
135Joint contractures involving the joints of the feet (HP:0100492)1.44400576
136Flexion contracture of toe (HP:0005830)1.44400576
137Myocardial infarction (HP:0001658)1.43381003

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K17.07296882
2ERN14.22018482
3BLK4.08027399
4PRKCH3.34883708
5SYK3.34099150
6CSF1R3.06267677
7PRPF4B3.03918439
8GRK62.58890849
9RIPK42.41941243
10LRRK22.39429217
11BTK2.36203442
12MST1R2.33803350
13KIT2.32515810
14PRKCI2.25857792
15STK102.23537093
16SMG12.19469748
17LYN1.99471065
18TRIB31.95509388
19MST41.93449056
20PRKCQ1.92801823
21BUB11.61487466
22RIPK11.61291858
23SIK31.60641674
24MAP3K131.56120456
25MAP3K101.48597565
26ITK1.48536865
27TYK21.46318965
28CDC71.44158108
29CLK11.41007908
30TBK11.40662023
31MAP3K141.22733649
32JAK31.21337273
33BMPR21.18787873
34CSK1.18311626
35CDC42BPA1.14926229
36TGFBR21.14363149
37FGFR41.14016346
38NEK21.12745250
39ZAP701.10750274
40IRAK11.10190585
41TEC1.08259757
42EIF2AK31.03920282
43STK241.03915614
44TESK21.02186464
45HCK0.98230140
46KDR0.95645070
47PKN20.95310793
48TGFBR10.94463280
49LCK0.94340098
50MAP3K10.93421964
51MAP3K90.91301941
52ALK0.89046142
53FES0.88376434
54CCNB10.86528796
55JAK10.85875191
56MATK0.85550488
57MAPK70.83678285
58DDR20.81754852
59PDGFRA0.81355425
60FGFR30.76844319
61BCR0.75951894
62CSNK1G30.75856982
63EIF2AK10.72993617
64TAOK30.72320997
65CSNK1A1L0.70818500
66TNK20.69875016
67RPS6KA40.68282575
68PRKCD0.67704367
69FER0.67256805
70CSNK1G10.65115532
71SIK20.64678706
72TXK0.62908519
73EPHA20.62540902
74EPHB10.62393315
75GRK10.62362159
76DMPK0.62143311
77TTN0.61691594
78KSR20.61127526
79MET0.60296195
80MAPKAPK30.59275387
81NEK90.58192968
82IKBKB0.57218220
83CDK120.55569275
84FYN0.55455285
85CHUK0.54913324
86TAOK10.54378949
87NLK0.53706594
88PRKCZ0.52056842
89SIK10.51090863
90YES10.49860763
91MAPK110.49686316
92PDK10.49146736
93RET0.48026634
94IKBKE0.46808060
95PRKD10.46720226
96TLK10.46674347
97ABL10.46461397
98MAP3K30.45969665
99MAPK120.45697986
100MAP3K80.44420430
101MAP3K60.44181827
102IRAK40.43762389
103CSNK1G20.43648029
104INSR0.43313409
105MELK0.42738721
106BRSK10.41058001
107MARK30.40189873
108PRKD20.39840304
109EPHA30.39489393
110MAP2K30.39226732
111NME10.36675670
112FGR0.36593322
113PDPK10.36120572
114TAF10.35387838
115SCYL20.35188365
116PIK3CG0.34189466
117TESK10.34058550
118HIPK20.32854346
119CDK40.32663153
120PRKCE0.32309554
121PRKG20.32127359
122MAP3K110.31933432
123TIE10.31818480
124EGFR0.31597661
125DAPK30.29911997
126PTK60.29758740
127JAK20.29667657
128MAPK40.26453146
129NME20.25997045
130RPS6KA50.25895222
131MAPK30.25411036
132CAMKK10.24130613
133CDK60.23730826
134ARAF0.23159028
135MAPKAPK20.22508578
136FGFR20.20045100
137CSNK1D0.19541024
138SRC0.15814191
139EEF2K0.15464916
140MAP2K10.15400664
141PRKCG0.14953686
142FRK0.14021626

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053408.11951174
2B cell receptor signaling pathway_Homo sapiens_hsa046625.51605028
3Intestinal immune network for IgA production_Homo sapiens_hsa046724.99103462
4Asthma_Homo sapiens_hsa053104.15085301
5DNA replication_Homo sapiens_hsa030303.38856673
6Base excision repair_Homo sapiens_hsa034103.31173780
7Mismatch repair_Homo sapiens_hsa034303.23100161
8Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.86058462
9Antigen processing and presentation_Homo sapiens_hsa046122.44260657
10NF-kappa B signaling pathway_Homo sapiens_hsa040642.29136483
11Systemic lupus erythematosus_Homo sapiens_hsa053222.11539601
12Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.94954986
13Hematopoietic cell lineage_Homo sapiens_hsa046401.85032120
14Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.61092523
15Osteoclast differentiation_Homo sapiens_hsa043801.55761259
16Rheumatoid arthritis_Homo sapiens_hsa053231.47674769
17Leukocyte transendothelial migration_Homo sapiens_hsa046701.39174583
18Shigellosis_Homo sapiens_hsa051311.38414912
19Leishmaniasis_Homo sapiens_hsa051401.36227513
20Viral myocarditis_Homo sapiens_hsa054161.32143186
21Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.30572474
22Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.30256469
23T cell receptor signaling pathway_Homo sapiens_hsa046601.28611118
24Homologous recombination_Homo sapiens_hsa034401.17634120
25Phagosome_Homo sapiens_hsa041451.16515730
26Cyanoamino acid metabolism_Homo sapiens_hsa004601.16376300
27Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.14157129
28Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.11206576
29Nucleotide excision repair_Homo sapiens_hsa034201.07852685
30Tuberculosis_Homo sapiens_hsa051521.07385825
31Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.06960368
32Herpes simplex infection_Homo sapiens_hsa051680.99325367
33Chemokine signaling pathway_Homo sapiens_hsa040620.97855389
34Other glycan degradation_Homo sapiens_hsa005110.96894968
35Non-small cell lung cancer_Homo sapiens_hsa052230.95400310
36Pancreatic cancer_Homo sapiens_hsa052120.91957581
37Fructose and mannose metabolism_Homo sapiens_hsa000510.91274506
38VEGF signaling pathway_Homo sapiens_hsa043700.84307308
39Platelet activation_Homo sapiens_hsa046110.81841657
40Toxoplasmosis_Homo sapiens_hsa051450.81039701
41Allograft rejection_Homo sapiens_hsa053300.80644358
42Apoptosis_Homo sapiens_hsa042100.79136719
43Epstein-Barr virus infection_Homo sapiens_hsa051690.78405741
44Caffeine metabolism_Homo sapiens_hsa002320.76072364
45Measles_Homo sapiens_hsa051620.74580299
46Pertussis_Homo sapiens_hsa051330.72808429
47Proteasome_Homo sapiens_hsa030500.72807344
48Hepatitis B_Homo sapiens_hsa051610.72764675
49Salmonella infection_Homo sapiens_hsa051320.71360186
50HTLV-I infection_Homo sapiens_hsa051660.69877948
51Renin-angiotensin system_Homo sapiens_hsa046140.66073235
52AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.65817293
53Tryptophan metabolism_Homo sapiens_hsa003800.63929436
54Neurotrophin signaling pathway_Homo sapiens_hsa047220.63377348
55Type I diabetes mellitus_Homo sapiens_hsa049400.63005532
56Cell cycle_Homo sapiens_hsa041100.60922022
57Influenza A_Homo sapiens_hsa051640.58540200
58Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.58138061
59Graft-versus-host disease_Homo sapiens_hsa053320.53547775
60Staphylococcus aureus infection_Homo sapiens_hsa051500.51434443
61Toll-like receptor signaling pathway_Homo sapiens_hsa046200.51249067
62Viral carcinogenesis_Homo sapiens_hsa052030.50413516
63Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.50171911
64Pentose phosphate pathway_Homo sapiens_hsa000300.49123542
65alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.48967141
66Transcriptional misregulation in cancer_Homo sapiens_hsa052020.48713899
67Non-homologous end-joining_Homo sapiens_hsa034500.48601695
68Arginine biosynthesis_Homo sapiens_hsa002200.47055094
69Spliceosome_Homo sapiens_hsa030400.46907955
70Protein digestion and absorption_Homo sapiens_hsa049740.45199945
71Carbohydrate digestion and absorption_Homo sapiens_hsa049730.43403917
72Acute myeloid leukemia_Homo sapiens_hsa052210.41356138
73Chronic myeloid leukemia_Homo sapiens_hsa052200.41230722
74Phenylalanine metabolism_Homo sapiens_hsa003600.41068309
75Prolactin signaling pathway_Homo sapiens_hsa049170.40914549
76Small cell lung cancer_Homo sapiens_hsa052220.40757935
77Fat digestion and absorption_Homo sapiens_hsa049750.40724593
78Alcoholism_Homo sapiens_hsa050340.40284053
79Arachidonic acid metabolism_Homo sapiens_hsa005900.40227398
80Jak-STAT signaling pathway_Homo sapiens_hsa046300.39617572
81Prion diseases_Homo sapiens_hsa050200.39442698
82p53 signaling pathway_Homo sapiens_hsa041150.39309814
83Amoebiasis_Homo sapiens_hsa051460.39273199
84Renal cell carcinoma_Homo sapiens_hsa052110.38488844
85African trypanosomiasis_Homo sapiens_hsa051430.37765565
86Endocytosis_Homo sapiens_hsa041440.35688170
87Autoimmune thyroid disease_Homo sapiens_hsa053200.35608681
88Insulin resistance_Homo sapiens_hsa049310.34946219
89Bladder cancer_Homo sapiens_hsa052190.34659260
90Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.33327135
91N-Glycan biosynthesis_Homo sapiens_hsa005100.33073267
92Lysosome_Homo sapiens_hsa041420.32787829
93Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.32687747
94Regulation of actin cytoskeleton_Homo sapiens_hsa048100.32666198
95Proteoglycans in cancer_Homo sapiens_hsa052050.32332164
96Glioma_Homo sapiens_hsa052140.30847389
97RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.30570152
98Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.30456270
99Sulfur metabolism_Homo sapiens_hsa009200.29538332
100Sphingolipid signaling pathway_Homo sapiens_hsa040710.28392651
101Notch signaling pathway_Homo sapiens_hsa043300.28155542
102Dorso-ventral axis formation_Homo sapiens_hsa043200.28120785
103TNF signaling pathway_Homo sapiens_hsa046680.27901667
104Adherens junction_Homo sapiens_hsa045200.27783187
105HIF-1 signaling pathway_Homo sapiens_hsa040660.27541374
106Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.26227952
107Linoleic acid metabolism_Homo sapiens_hsa005910.25889541
108Hepatitis C_Homo sapiens_hsa051600.25729128
109MicroRNAs in cancer_Homo sapiens_hsa052060.25256422
110Ribosome_Homo sapiens_hsa030100.24673277
111Colorectal cancer_Homo sapiens_hsa052100.23564244
112Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.21915678
113Malaria_Homo sapiens_hsa051440.21415654
114Pancreatic secretion_Homo sapiens_hsa049720.21122286
115GnRH signaling pathway_Homo sapiens_hsa049120.20684336
116MAPK signaling pathway_Homo sapiens_hsa040100.20285037
117Histidine metabolism_Homo sapiens_hsa003400.20266713
118Thyroid hormone synthesis_Homo sapiens_hsa049180.19616974
119Drug metabolism - other enzymes_Homo sapiens_hsa009830.18957265
120Focal adhesion_Homo sapiens_hsa045100.18042591
121Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.17986840
122cGMP-PKG signaling pathway_Homo sapiens_hsa040220.17771923
123Legionellosis_Homo sapiens_hsa051340.17241288
124Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.16691473
125Ether lipid metabolism_Homo sapiens_hsa005650.15559535
126Pyrimidine metabolism_Homo sapiens_hsa002400.15093354
127Long-term potentiation_Homo sapiens_hsa047200.14820239
128Glycosaminoglycan degradation_Homo sapiens_hsa005310.14678892
129Galactose metabolism_Homo sapiens_hsa000520.14540455
130Complement and coagulation cascades_Homo sapiens_hsa046100.14138918
131Oocyte meiosis_Homo sapiens_hsa041140.13278122
132Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.13098097
133Prostate cancer_Homo sapiens_hsa052150.12119783
134NOD-like receptor signaling pathway_Homo sapiens_hsa046210.11875568
135Central carbon metabolism in cancer_Homo sapiens_hsa052300.11838698
136Adipocytokine signaling pathway_Homo sapiens_hsa049200.11569290
137Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.10496628
138Inositol phosphate metabolism_Homo sapiens_hsa005620.10283263
139Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.09174593

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »