IGHG3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of respiratory burst (GO:0060267)8.11750598
2antigen processing and presentation of endogenous antigen (GO:0019883)7.67325728
3B cell receptor signaling pathway (GO:0050853)7.14886304
4* Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096)7.06625362
5* immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:00027.06625362
6* Fc-gamma receptor signaling pathway (GO:0038094)7.06625362
7glomerular filtration (GO:0003094)7.00877137
8* Fc receptor mediated stimulatory signaling pathway (GO:0002431)6.96762158
9* protein activation cascade (GO:0072376)6.69139272
10antigen processing and presentation of endogenous peptide antigen (GO:0002483)6.55272358
11antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.55272358
12renal filtration (GO:0097205)6.33832921
13positive regulation of B cell differentiation (GO:0045579)6.11700641
14* humoral immune response (GO:0006959)6.06249947
15negative regulation of B cell proliferation (GO:0030889)5.84496878
16regulation of B cell differentiation (GO:0045577)5.73026793
17regulation of B cell receptor signaling pathway (GO:0050855)5.72888829
18cellular response to zinc ion (GO:0071294)5.56495646
19regulation of respiratory burst (GO:0060263)5.46583083
20negative regulation of glucose import (GO:0046325)5.11100533
21positive regulation of gamma-delta T cell activation (GO:0046645)5.08406835
22regulation of B cell proliferation (GO:0030888)4.98399327
23* immune response-activating cell surface receptor signaling pathway (GO:0002429)4.93440800
24cytidine deamination (GO:0009972)4.88541177
25cytidine metabolic process (GO:0046087)4.88541177
26cytidine catabolic process (GO:0006216)4.88541177
27regulation of dendritic cell antigen processing and presentation (GO:0002604)4.64044684
28regulation of cellular extravasation (GO:0002691)4.60544023
29regulation of glucose import in response to insulin stimulus (GO:2001273)4.60450973
30immunoglobulin mediated immune response (GO:0016064)4.30844523
31positive regulation of antigen processing and presentation (GO:0002579)4.30045221
32mature B cell differentiation (GO:0002335)4.27660376
33negative regulation of glucose transport (GO:0010829)4.21149200
34detection of bacterium (GO:0016045)4.14381680
35positive regulation of Rap GTPase activity (GO:0032854)4.11984604
36negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)4.09159523
37regulation of gamma-delta T cell differentiation (GO:0045586)4.07565211
38interferon-gamma-mediated signaling pathway (GO:0060333)4.06870723
39detection of other organism (GO:0098543)4.00181346
40negative regulation of cell killing (GO:0031342)3.91089078
41negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.91089078
42regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.89981508
43regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.79544965
44somatic hypermutation of immunoglobulin genes (GO:0016446)3.78604339
45somatic diversification of immune receptors via somatic mutation (GO:0002566)3.78604339
46B cell proliferation (GO:0042100)3.74267714
47positive thymic T cell selection (GO:0045059)3.70029292
48cellular response to type I interferon (GO:0071357)3.69953928
49type I interferon signaling pathway (GO:0060337)3.69953928
50response to type I interferon (GO:0034340)3.69829036
51positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.65002683
52regulation of gamma-delta T cell activation (GO:0046643)3.64001430
53pyrimidine ribonucleoside catabolic process (GO:0046133)3.61556827
54regulation of antigen processing and presentation (GO:0002577)3.56668841
55regulation of interferon-beta biosynthetic process (GO:0045357)3.56161221
56positive regulation of immunoglobulin production (GO:0002639)3.55530853
57antigen receptor-mediated signaling pathway (GO:0050851)3.52657495
58regulation of B cell activation (GO:0050864)3.48874661
59B cell homeostasis (GO:0001782)3.47623831
60antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.47176240
61thymic T cell selection (GO:0045061)3.45313949
62regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.44422827
63positive regulation of pseudopodium assembly (GO:0031274)3.43742865
64regulation of Rap GTPase activity (GO:0032317)3.43266056
65negative thymic T cell selection (GO:0045060)3.42593934
66* immune response-activating signal transduction (GO:0002757)3.41845633
67Fc-epsilon receptor signaling pathway (GO:0038095)3.40463088
68ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)3.39341626
69positive regulation of Cdc42 GTPase activity (GO:0043089)3.39125311
70positive regulation of Rho protein signal transduction (GO:0035025)3.37904493
71respiratory burst (GO:0045730)3.37550015
72angiotensin maturation (GO:0002003)3.36902311
73germinal center formation (GO:0002467)3.36781519
74negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.29933958
75cellular response to interferon-gamma (GO:0071346)3.29847011
76positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.29259938
77regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)3.25440252
78* immune response-regulating cell surface receptor signaling pathway (GO:0002768)3.25076455
79regulation of B cell apoptotic process (GO:0002902)3.24630716
80B cell mediated immunity (GO:0019724)3.22494281
81chronic inflammatory response (GO:0002544)3.22195342
82maternal placenta development (GO:0001893)3.18485448
83response to interleukin-15 (GO:0070672)3.16392336
84regulation of interleukin-12 biosynthetic process (GO:0045075)3.16164686
85T-helper 1 type immune response (GO:0042088)3.14741151
86negative T cell selection (GO:0043383)3.12882323
87response to interferon-gamma (GO:0034341)3.11145641
88T cell selection (GO:0045058)3.10694578
89positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.09948048
90* activation of immune response (GO:0002253)3.09360050
91regulation of superoxide anion generation (GO:0032928)3.09041551
92myeloid dendritic cell differentiation (GO:0043011)3.08173782
93positive regulation of B cell activation (GO:0050871)3.07959658
94mature B cell differentiation involved in immune response (GO:0002313)3.07636951
95regulation of integrin activation (GO:0033623)3.07541493
96* Fc receptor signaling pathway (GO:0038093)3.07096589
97regulation of pseudopodium assembly (GO:0031272)3.06223210
98T cell costimulation (GO:0031295)3.05962045
99signal peptide processing (GO:0006465)3.02955548
100NIK/NF-kappaB signaling (GO:0038061)3.02900315
101positive regulation of B cell proliferation (GO:0030890)3.02876052
102detection of external biotic stimulus (GO:0098581)3.00448665
103B cell activation (GO:0042113)2.99222531
104lymphocyte costimulation (GO:0031294)2.97911686
105lymphocyte homeostasis (GO:0002260)2.97723847
106antimicrobial humoral response (GO:0019730)2.97284401
107dendritic cell chemotaxis (GO:0002407)2.95201974
108negative regulation of B cell activation (GO:0050869)2.93633233
109regulation of T-helper 1 cell differentiation (GO:0045625)2.90111177
110antibacterial humoral response (GO:0019731)2.90044083
111negative regulation of phagocytosis (GO:0050765)2.86753051
112regulation of nuclease activity (GO:0032069)2.86739783
113activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.85887398
114positive regulation of nuclease activity (GO:0032075)2.85095358
115regulation of T cell tolerance induction (GO:0002664)2.81122814
116surfactant homeostasis (GO:0043129)2.79931310
117myeloid dendritic cell activation (GO:0001773)2.79818219
118bone resorption (GO:0045453)2.77078422
119production of molecular mediator of immune response (GO:0002440)2.77000224
120positive regulation of neutrophil chemotaxis (GO:0090023)2.76959344
121positive regulation of neutrophil migration (GO:1902624)2.76959344
122fucose catabolic process (GO:0019317)2.76926607
123L-fucose metabolic process (GO:0042354)2.76926607
124L-fucose catabolic process (GO:0042355)2.76926607
125defense response to Gram-negative bacterium (GO:0050829)2.75629043
126positive regulation of interleukin-2 production (GO:0032743)2.75503929
127regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)2.74875632
128cellular response to interleukin-15 (GO:0071350)2.74704505
129regulation of type I interferon-mediated signaling pathway (GO:0060338)2.74401825
130* retina homeostasis (GO:0001895)2.74100108
131peptide catabolic process (GO:0043171)2.73524920
132N-acetylneuraminate metabolic process (GO:0006054)2.72849353
133regulation of alpha-beta T cell proliferation (GO:0046640)2.72258156
134regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.71625895
135positive regulation of granulocyte chemotaxis (GO:0071624)2.71416382
136positive regulation of T cell migration (GO:2000406)2.71054688
137regulation of T cell migration (GO:2000404)2.64967995
138defense response to protozoan (GO:0042832)2.62153168
139virion attachment to host cell (GO:0019062)2.59530669
140adhesion of symbiont to host cell (GO:0044650)2.59530669
141eosinophil chemotaxis (GO:0048245)2.55330651
142detection of biotic stimulus (GO:0009595)2.53120076
143regulation of tolerance induction (GO:0002643)2.50919360
144protein-chromophore linkage (GO:0018298)2.50075885
145antigen processing and presentation via MHC class Ib (GO:0002475)2.47520278
146positive regulation of lymphocyte migration (GO:2000403)2.47423228
147positive regulation of lipid kinase activity (GO:0090218)2.46720510
148maintenance of gastrointestinal epithelium (GO:0030277)2.46075190
149positive regulation of type 2 immune response (GO:0002830)2.46023213
150interferon-gamma secretion (GO:0072643)2.43973316
151dendritic cell differentiation (GO:0097028)2.42855055
152regulation of necrotic cell death (GO:0010939)2.42811847
153dendritic cell migration (GO:0036336)2.42305270
154regulation of regulatory T cell differentiation (GO:0045589)2.41602114
155positive regulation of phosphatidylinositol 3-kinase activity (GO:0043552)2.37719247
156adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.37216636
157eosinophil migration (GO:0072677)2.35914772
158regulation of lymphocyte migration (GO:2000401)2.34961511
159negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.34309654
160GDP-mannose metabolic process (GO:0019673)2.33581019
161production of molecular mediator involved in inflammatory response (GO:0002532)2.33527517
162modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.33354009
163modulation by symbiont of host immune response (GO:0052553)2.33354009
164* complement activation, classical pathway (GO:0006958)14.0569596
165* complement activation (GO:0006956)10.6531904

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.01310673
2BP1_19119308_ChIP-ChIP_Hs578T_Human5.05494098
3MYC_22102868_ChIP-Seq_BL_Human4.99438021
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.85410565
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.67779671
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.09070173
7IRF8_21731497_ChIP-ChIP_J774_Mouse3.88594120
8SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.81928991
9E2F7_22180533_ChIP-Seq_HELA_Human3.73811302
10TP63_17297297_ChIP-ChIP_HaCaT_Human3.71668430
11E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human3.52308945
12EGR1_19374776_ChIP-ChIP_THP-1_Human3.39956454
13VDR_21846776_ChIP-Seq_THP-1_Human3.12159577
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.11060892
15IRF8_27001747_Chip-Seq_BMDM_Mouse3.02445732
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.85655078
17FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.72390182
18MAF_26560356_Chip-Seq_TH1_Human2.71638778
19RUNX_20019798_ChIP-Seq_JUKART_Human2.61396593
20MYB_26560356_Chip-Seq_TH2_Human2.57898316
21MYB_26560356_Chip-Seq_TH1_Human2.55269596
22IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.42950443
23NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.39091583
24STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.27381491
25UTX_26944678_Chip-Seq_JUKART_Human2.25749597
26RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.21504423
27VDR_24763502_ChIP-Seq_THP-1_Human2.18490701
28NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.15708128
29NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.15614021
30FOXM1_23109430_ChIP-Seq_U2OS_Human2.11116828
31SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.05943080
32STAT4_19710469_ChIP-ChIP_TH1__Mouse2.03861606
33TCF7_22412390_ChIP-Seq_EML_Mouse1.96990857
34KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.93739633
35ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.84845092
36BRD4_27068464_Chip-Seq_AML-cells_Mouse1.82622327
37SPI1_23547873_ChIP-Seq_NB4_Human1.79642627
38SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.79278749
39KDM2B_26808549_Chip-Seq_DND41_Human1.76563851
40MAF_26560356_Chip-Seq_TH2_Human1.69655586
41KDM2B_26808549_Chip-Seq_SUP-B15_Human1.67938482
42TRIM28_21343339_ChIP-Seq_HEK293_Human1.65752201
43GATA3_27048872_Chip-Seq_THYMUS_Human1.65605137
44GATA1_22025678_ChIP-Seq_K562_Human1.65241880
45CDX2_20551321_ChIP-Seq_CACO-2_Human1.64989643
46RARG_19884340_ChIP-ChIP_MEFs_Mouse1.64175857
47MYB_21317192_ChIP-Seq_ERMYB_Mouse1.63272152
48VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.62097366
49PU.1_20513432_ChIP-Seq_Bcells_Mouse1.60184841
50TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.55336634
51RUNX1_22412390_ChIP-Seq_EML_Mouse1.54278170
52CLOCK_20551151_ChIP-Seq_293T_Human1.53881131
53SCL_19346495_ChIP-Seq_HPC-7_Human1.52895084
54STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.52805872
55SPI1_23127762_ChIP-Seq_K562_Human1.50739845
56PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.49677964
57BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.49389086
58RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.49367859
59SOX2_27498859_Chip-Seq_STOMACH_Mouse1.49276812
60TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.48576731
61ELK3_25401928_ChIP-Seq_HUVEC_Human1.44895595
62KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.44128145
63MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.39061678
64CIITA_25753668_ChIP-Seq_RAJI_Human1.34048037
65GATA2_22383799_ChIP-Seq_G1ME_Mouse1.31935175
66GATA3_26560356_Chip-Seq_TH2_Human1.31934362
67EGR1_19032775_ChIP-ChIP_M12_Human1.31246386
68EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.30239203
69FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.29388562
70RACK7_27058665_Chip-Seq_MCF-7_Human1.29206763
71MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.28271368
72GATA1_22383799_ChIP-Seq_G1ME_Mouse1.26018508
73IKZF1_21737484_ChIP-ChIP_HCT116_Human1.25906650
74TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.19953334
75FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.19813399
76STAT6_21828071_ChIP-Seq_BEAS2B_Human1.19786834
77TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.19784042
78NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.18790638
79SOX2_20726797_ChIP-Seq_SW620_Human1.16041559
80DNAJC2_21179169_ChIP-ChIP_NT2_Human1.15652373
81RXR_22158963_ChIP-Seq_LIVER_Mouse1.15644442
82P63_26484246_Chip-Seq_KERATINOCYTES_Human1.14104699
83THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.13165685
84ESR2_21235772_ChIP-Seq_MCF-7_Human1.09141594
85LXR_22292898_ChIP-Seq_THP-1_Human1.08357638
86Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.07449279
87ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.07105839
88PU_27001747_Chip-Seq_BMDM_Mouse1.06234892
89NOTCH1_21737748_ChIP-Seq_TLL_Human1.05242742
90VDR_24787735_ChIP-Seq_THP-1_Human1.04310097
91KDM5A_27292631_Chip-Seq_BREAST_Human1.03553140
92KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.02455481
93SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01499300
94GATA1_19941826_ChIP-Seq_K562_Human1.01320913
95GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.00041973
96LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.00020249
97P300_27268052_Chip-Seq_Bcells_Human0.99813933
98LXR_22158963_ChIP-Seq_LIVER_Mouse0.99712705
99TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.98402168
100SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.97930916
101CTCF_27219007_Chip-Seq_ERYTHROID_Human0.97488228
102PPARA_22158963_ChIP-Seq_LIVER_Mouse0.96803756
103GATA4_25053715_ChIP-Seq_YYC3_Human0.96742171
104PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.96094283
105GATA1_19941827_ChIP-Seq_MEL_Mouse0.96066815
106GATA2_21666600_ChIP-Seq_HMVEC_Human0.95274459
107CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.94818263
108FOXO3_23340844_ChIP-Seq_DLD1_Human0.93210005
109ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.92235164
110CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.92115853
111GATA6_25053715_ChIP-Seq_YYC3_Human0.92053867
112TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.91932523
113NCOR1_26117541_ChIP-Seq_K562_Human0.91539530
114GATA2_19941826_ChIP-Seq_K562_Human0.90913021
115BCL6_27268052_Chip-Seq_Bcells_Human0.90893579
116GATA3_26560356_Chip-Seq_TH1_Human0.89649253
117BCOR_27268052_Chip-Seq_Bcells_Human0.89274279
118CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.89176260
119ESR1_21235772_ChIP-Seq_MCF-7_Human0.88019754
120PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87782829
121SMRT_27268052_Chip-Seq_Bcells_Human0.87747847
122STAT1_20625510_ChIP-Seq_HELA_Human0.87422103
123RUNX1_27514584_Chip-Seq_MCF-7_Human0.87383222
124ELF1_17652178_ChIP-ChIP_JURKAT_Human0.87022043
125DROSHA_22980978_ChIP-Seq_HELA_Human0.86284365
126KDM2B_26808549_Chip-Seq_JURKAT_Human0.83448023
127PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.82249618
128ELF1_20517297_ChIP-Seq_JURKAT_Human0.81777570
129GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81643274
130CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.81292208
131CTCF_26484167_Chip-Seq_Bcells_Mouse0.80972140
132PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.80168145
133KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.78786782
134SPI1_20517297_ChIP-Seq_HL60_Human0.76347325
135SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.75635222
136LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.75577990
137RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74272409
138SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.74206352
139SMAD_19615063_ChIP-ChIP_OVARY_Human0.71450875

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation5.55048164
2MP0001800_abnormal_humoral_immune4.92019268
3MP0003303_peritoneal_inflammation4.68009847
4MP0003724_increased_susceptibility_to4.39272186
5MP0001790_abnormal_immune_system4.30416136
6MP0005387_immune_system_phenotype4.30416136
7MP0000685_abnormal_immune_system3.94753630
8MP0002452_abnormal_antigen_presenting3.65337963
9MP0005671_abnormal_response_to3.12660383
10MP0002723_abnormal_immune_serum3.08327363
11MP0002420_abnormal_adaptive_immunity2.97884909
12MP0005000_abnormal_immune_tolerance2.95871412
13MP0001819_abnormal_immune_cell2.91128075
14MP0002398_abnormal_bone_marrow2.79044069
15MP0000716_abnormal_immune_system2.65825795
16MP0003300_gastrointestinal_ulcer2.54690047
17MP0000689_abnormal_spleen_morphology2.46896974
18MP0009333_abnormal_splenocyte_physiolog2.25584700
19MP0005025_abnormal_response_to2.24228546
20MP0003763_abnormal_thymus_physiology2.23155459
21MP0002429_abnormal_blood_cell2.18969917
22MP0005166_decreased_susceptibility_to2.02479837
23MP0002722_abnormal_immune_system2.00322614
24MP0003436_decreased_susceptibility_to1.98225983
25MP0002166_altered_tumor_susceptibility1.98171480
26MP0004782_abnormal_surfactant_physiolog1.97845933
27MP0004510_myositis1.95284803
28MP0002148_abnormal_hypersensitivity_rea1.94443933
29MP0001879_abnormal_lymphatic_vessel1.93103071
30MP0001873_stomach_inflammation1.92556694
31MP0006054_spinal_hemorrhage1.91295520
32MP0005275_abnormal_skin_tensile1.89343977
33MP0002419_abnormal_innate_immunity1.86894944
34MP0004858_abnormal_nervous_system1.86662976
35MP0001845_abnormal_inflammatory_respons1.85143790
36MP0002405_respiratory_system_inflammati1.78976464
37MP0010234_abnormal_vibrissa_follicle1.65349171
38MP0002138_abnormal_hepatobiliary_system1.65272291
39MP0010155_abnormal_intestine_physiology1.62457379
40MP0008057_abnormal_DNA_replication1.57581669
41MP0005310_abnormal_salivary_gland1.53848361
42MP0004947_skin_inflammation1.52063735
43MP0009840_abnormal_foam_cell1.47216772
44MP0002006_tumorigenesis1.46435689
45MP0002396_abnormal_hematopoietic_system1.45778556
46MP0009785_altered_susceptibility_to1.44396136
47MP0005360_urolithiasis1.42446074
48MP0000465_gastrointestinal_hemorrhage1.41906704
49MP0003075_altered_response_to1.37203980
50MP0008438_abnormal_cutaneous_collagen1.33738107
51MP0003045_fibrosis1.29735737
52MP0000703_abnormal_thymus_morphology1.28116057
53MP0008004_abnormal_stomach_pH1.27848066
54MP0000604_amyloidosis1.27282193
55MP0003448_altered_tumor_morphology1.27134334
56MP0000343_altered_response_to1.26202847
57MP0002796_impaired_skin_barrier1.25941699
58MP0005464_abnormal_platelet_physiology1.25778752
59MP0005023_abnormal_wound_healing1.25365819
60MP0003279_aneurysm1.25093195
61MP0001853_heart_inflammation1.24187346
62MP0003183_abnormal_peptide_metabolism1.21849702
63MP0003866_abnormal_defecation1.16708611
64MP0009278_abnormal_bone_marrow1.16052673
65MP0004264_abnormal_extraembryonic_tissu1.15628807
66MP0002019_abnormal_tumor_incidence1.14443461
67MP0002933_joint_inflammation1.14372864
68MP0003329_amyloid_beta_deposits1.09194133
69MP0002136_abnormal_kidney_physiology1.08932690
70MP0000858_altered_metastatic_potential1.08010662
71MP0001666_abnormal_nutrient_absorption1.05235697
72MP0005503_abnormal_tendon_morphology1.05088417
73MP0003453_abnormal_keratinocyte_physiol1.03220386
74MP0005390_skeleton_phenotype1.02844409
75MP0009764_decreased_sensitivity_to1.02077711
76MP0000249_abnormal_blood_vessel0.99696277
77MP0005409_darkened_coat_color0.98508080
78MP0006082_CNS_inflammation0.97954599
79MP0001851_eye_inflammation0.97072357
80MP0004808_abnormal_hematopoietic_stem0.96831340
81MP0010352_gastrointestinal_tract_polyps0.95652000
82MP0005058_abnormal_lysosome_morphology0.92468737
83MP0005164_abnormal_response_to0.91860086
84MP0008469_abnormal_protein_level0.91772201
85MP0002139_abnormal_hepatobiliary_system0.90441384
86MP0008260_abnormal_autophagy0.89468342
87MP0002254_reproductive_system_inflammat0.87502708
88MP0001663_abnormal_digestive_system0.86255853
89MP0002277_abnormal_respiratory_mucosa0.83905653
90MP0005076_abnormal_cell_differentiation0.83385635
91MP0000681_abnormal_thyroid_gland0.78990846
92MP0000490_abnormal_crypts_of0.78202294
93MP0001664_abnormal_digestion0.76932086
94MP0008961_abnormal_basal_metabolism0.76150253
95MP0002168_other_aberrant_phenotype0.74847073
96MP0005397_hematopoietic_system_phenotyp0.74708806
97MP0001545_abnormal_hematopoietic_system0.74708806
98MP0005451_abnormal_body_composition0.73698203
99MP0001216_abnormal_epidermal_layer0.72597319
100MP0003693_abnormal_embryo_hatching0.71572623
101MP0003566_abnormal_cell_adhesion0.69915109
102MP0001348_abnormal_lacrimal_gland0.69884322
103MP0000609_abnormal_liver_physiology0.69601617
104MP0003091_abnormal_cell_migration0.69310294
105MP0001533_abnormal_skeleton_physiology0.68475497
106MP0003077_abnormal_cell_cycle0.67236587
107MP0002693_abnormal_pancreas_physiology0.65540458
108MP0009643_abnormal_urine_homeostasis0.63462716
109MP0000733_abnormal_muscle_development0.60754185
110MP0001919_abnormal_reproductive_system0.60483715
111MP0000003_abnormal_adipose_tissue0.60310729
112MP0003191_abnormal_cellular_cholesterol0.59877120
113MP0003656_abnormal_erythrocyte_physiolo0.59278426
114MP0003828_pulmonary_edema0.57766857
115MP0008874_decreased_physiological_sensi0.56004887
116MP0002133_abnormal_respiratory_system0.55909864
117MP0005388_respiratory_system_phenotype0.55909864
118MP0010094_abnormal_chromosome_stability0.55683718
119MP0001958_emphysema0.55590058
120MP0002083_premature_death0.54277964
121MP0009763_increased_sensitivity_to0.53362376
122MP0001944_abnormal_pancreas_morphology0.51568594
123MP0005389_reproductive_system_phenotype0.51276655
124MP0002998_abnormal_bone_remodeling0.51000667
125MP0000477_abnormal_intestine_morphology0.50470867
126MP0001730_embryonic_growth_arrest0.49105000
127MP0002928_abnormal_bile_duct0.48270485
128MP0001191_abnormal_skin_condition0.48254022
129MP0002876_abnormal_thyroid_physiology0.47340952
130MP0003787_abnormal_imprinting0.47276767
131MP0008872_abnormal_physiological_respon0.46751833
132MP0000350_abnormal_cell_proliferation0.46733773
133MP0005584_abnormal_enzyme/coenzyme_acti0.46431581
134MP0005621_abnormal_cell_physiology0.44995208
135MP0005381_digestive/alimentary_phenotyp0.44762801
136MP0008569_lethality_at_weaning0.44286677

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)9.83165479
2Recurrent sinusitis (HP:0011108)7.27480099
3Colitis (HP:0002583)7.22924510
4Cellulitis (HP:0100658)7.01689194
5Abnormality of B cell number (HP:0010975)6.95932075
6B lymphocytopenia (HP:0010976)6.95932075
7Recurrent bronchitis (HP:0002837)6.84343212
8Systemic lupus erythematosus (HP:0002725)6.59471319
9Verrucae (HP:0200043)6.24828035
10Papilloma (HP:0012740)6.24828035
11Gastrointestinal stroma tumor (HP:0100723)5.96895922
12Inflammation of the large intestine (HP:0002037)5.83145299
13IgM deficiency (HP:0002850)5.77084627
14Gastrointestinal inflammation (HP:0004386)5.60667095
15Recurrent viral infections (HP:0004429)5.49405653
16Meningitis (HP:0001287)5.07394591
17Recurrent pneumonia (HP:0006532)4.84169565
18Prostate neoplasm (HP:0100787)4.80622867
19Chronic otitis media (HP:0000389)4.77074467
20Malnutrition (HP:0004395)4.74451648
21Chronic sinusitis (HP:0011109)4.46296068
22Recurrent lower respiratory tract infections (HP:0002783)4.36470501
23Osteomyelitis (HP:0002754)4.25349495
24Abnormality of complement system (HP:0005339)4.22575373
25Emphysema (HP:0002097)4.11747357
26Glomerulonephritis (HP:0000099)4.08487485
27Bronchitis (HP:0012387)4.07868960
28Complement deficiency (HP:0004431)3.98217309
29Recurrent otitis media (HP:0000403)3.83617422
30IgA deficiency (HP:0002720)3.73636838
31Panhypogammaglobulinemia (HP:0003139)3.71539738
32Abnormality of the prostate (HP:0008775)3.69941350
33Sepsis (HP:0100806)3.67374787
34Abnormal delayed hypersensitivity skin test (HP:0002963)3.67220903
35Lymphopenia (HP:0001888)3.50167841
36Recurrent abscess formation (HP:0002722)3.39894004
37IgG deficiency (HP:0004315)3.39360802
38Nephritis (HP:0000123)3.38143995
39Vasculitis (HP:0002633)3.37216936
40Interstitial pulmonary disease (HP:0006530)3.35840667
41Recurrent fungal infections (HP:0002841)3.35059962
42Abnormality of cells of the lymphoid lineage (HP:0012140)3.34685225
43Recurrent bacterial skin infections (HP:0005406)3.29290512
44Increased IgE level (HP:0003212)3.25011755
45Thyroiditis (HP:0100646)3.11850442
46Restrictive lung disease (HP:0002091)3.10834506
47Nasal polyposis (HP:0100582)3.09994137
48Eczematoid dermatitis (HP:0000976)3.09558570
49Abnormality of T cell physiology (HP:0011840)3.07299124
50Premature loss of primary teeth (HP:0006323)3.05609907
51Gastrointestinal infarctions (HP:0005244)2.96810432
52Skin rash (HP:0000988)2.94021719
53Chronic diarrhea (HP:0002028)2.92947764
54Chronic mucocutaneous candidiasis (HP:0002728)2.80330958
55Recurrent cutaneous fungal infections (HP:0011370)2.80330958
56Recurrent skin infections (HP:0001581)2.80124856
57Abnormality of T cells (HP:0002843)2.80047958
58Abnormality of the nasal mucosa (HP:0000433)2.79072975
59Abnormality of glutamine family amino acid metabolism (HP:0010902)2.73515359
60Orchitis (HP:0100796)2.72288662
61Hemoptysis (HP:0002105)2.72210814
62Small epiphyses (HP:0010585)2.67409747
63Leukocytosis (HP:0001974)2.65254713
64Mediastinal lymphadenopathy (HP:0100721)2.50686196
65Recurrent gram-negative bacterial infections (HP:0005420)2.49396480
66Abnormality of T cell number (HP:0011839)2.48157228
67T lymphocytopenia (HP:0005403)2.45516558
68Bronchiectasis (HP:0002110)2.38861377
69Alopecia of scalp (HP:0002293)2.38699079
70Skin ulcer (HP:0200042)2.35832817
71Mitral stenosis (HP:0001718)2.35819399
72Purpura (HP:0000979)2.29600069
73Chronic obstructive pulmonary disease (HP:0006510)2.26213806
74Obstructive lung disease (HP:0006536)2.26213806
75Autoimmune thrombocytopenia (HP:0001973)2.25031246
76Optic neuritis (HP:0100653)2.23955179
77Retrobulbar optic neuritis (HP:0100654)2.23955179
78Pustule (HP:0200039)2.22830859
79Abnormality of male internal genitalia (HP:0000022)2.21692437
80Viral hepatitis (HP:0006562)2.16903108
81Spontaneous hematomas (HP:0007420)2.15569592
82Abnormality of the peritoneum (HP:0002585)2.10794836
83Neutropenia (HP:0001875)2.10588474
84Leukopenia (HP:0001882)2.10553841
85Abnormality of the pleura (HP:0002103)2.08658261
86Neoplasm of the lung (HP:0100526)2.06519845
87Lymphoma (HP:0002665)2.03542998
88Abnormality of monocarboxylic acid metabolism (HP:0010996)2.03495291
89Polycythemia (HP:0001901)2.03167204
90Hypermelanotic macule (HP:0001034)2.00517528
91Thrombocytosis (HP:0001894)2.00178950
92Pulmonary infiltrates (HP:0002113)1.99993559
93Abnormality of the fingertips (HP:0001211)1.99971898
94Ankyloglossia (HP:0010296)1.99560778
95Fragile skin (HP:0001030)1.97930160
96Combined immunodeficiency (HP:0005387)1.94384957
97Keratoconjunctivitis sicca (HP:0001097)1.94229249
98Elevated erythrocyte sedimentation rate (HP:0003565)1.92111483
99Hemorrhage of the eye (HP:0011885)1.92100339
100Urticaria (HP:0001025)1.91089024
101Dehydration (HP:0001944)1.90879688
102Increased IgM level (HP:0003496)1.90151241
103Pulmonary embolism (HP:0002204)1.88432678
104Segmental peripheral demyelination/remyelination (HP:0003481)1.86277167
105Encephalitis (HP:0002383)1.84587837
106Arthralgia (HP:0002829)1.82236140
107Autoimmune hemolytic anemia (HP:0001890)1.81812944
108Atrophic scars (HP:0001075)1.81422943
109Polygenic inheritance (HP:0010982)1.80509602
110Myositis (HP:0100614)1.78206518
111Hematochezia (HP:0002573)1.77728441
112Papilledema (HP:0001085)1.77282621
113Hypergammaglobulinemia (HP:0010702)1.73362308
114Basal cell carcinoma (HP:0002671)1.72624718
115Acrocyanosis (HP:0001063)1.67051461
116Flattened epiphyses (HP:0003071)1.65746332
117Eosinophilia (HP:0001880)1.61086539
118Xerostomia (HP:0000217)1.59618402
119Irregular vertebral endplates (HP:0003301)1.57154929
120Hypoplasia of the capital femoral epiphysis (HP:0003090)1.53792426
121Hepatitis (HP:0012115)1.52817375
122Mucosal telangiectasiae (HP:0100579)1.51256023
123Chest pain (HP:0100749)1.48831697
124Gingivitis (HP:0000230)1.47992339
125Abnormality of macrophages (HP:0004311)1.47877339
126Hypochromic anemia (HP:0001931)1.46463678
127Severe combined immunodeficiency (HP:0004430)1.45390980
128Teleangiectasia of the skin (HP:0100585)1.43535437
129Vertebral arch anomaly (HP:0008438)1.40812119
130Arterial thrombosis (HP:0004420)1.40482258
131Abnormality of small intestinal villus morphology (HP:0011472)1.39083489
132Villous atrophy (HP:0011473)1.39083489
133Erythema (HP:0010783)1.38306684
134Abnormal foot bone ossification (HP:0010675)1.37360668
135Ulnar deviation of the wrist (HP:0003049)1.36744546
136Keratoconjunctivitis (HP:0001096)1.36531794

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K16.68837635
2ERN16.32180988
3GRK63.11026042
4BLK3.02453322
5CSF1R2.73310799
6SYK2.72109058
7PRPF4B2.70206477
8MST1R2.66648078
9RIPK42.60969156
10MAP3K102.56653191
11TYK22.38681118
12RIPK12.19402548
13TAOK32.11774257
14STK102.04055065
15MAP3K141.99215273
16LRRK21.85899347
17BTK1.81225103
18SIK21.73422815
19PRKCH1.69546477
20KIT1.68063601
21JAK11.61698956
22EEF2K1.59569918
23MAP3K131.51661886
24IRAK31.47670576
25IRAK41.45213176
26TXK1.42989603
27LYN1.41198698
28TBK11.37044424
29NEK21.31888188
30EIF2AK31.29062540
31JAK31.25660016
32MAP3K11.25559667
33HCK1.24701769
34FES1.24044099
35PRKCQ1.23277024
36SMG11.19506974
37PDGFRA1.17400722
38TRIB31.16429081
39NME21.14821915
40ALK1.12026177
41ITK1.08748884
42CSK1.07395275
43HIPK21.06641401
44DDR21.06528682
45IKBKE1.06185673
46NEK91.06008609
47CDK121.05841677
48IRAK11.03795476
49FGFR41.03014444
50IKBKB1.02621158
51MST41.01277785
52TGFBR20.99450867
53EPHA20.95265996
54FGFR30.94178373
55PRKG20.92433027
56PIM10.91025025
57MARK30.90438933
58PIK3CA0.89803954
59TAOK10.89741576
60FER0.88626659
61LCK0.85767637
62CLK10.85676244
63MET0.82953871
64MAP3K30.82293107
65EPHB10.80815669
66ACVR1B0.76995976
67NLK0.75179024
68MAP3K90.74916307
69KSR20.72122495
70EPHB20.71395001
71ZAP700.71345240
72SIK10.70453211
73TEC0.69469063
74MAP3K110.68431764
75TNK20.68033058
76PRKD20.67229949
77MATK0.64743454
78SIK30.63593220
79RET0.61313057
80PDPK10.59049683
81FGR0.58477213
82PRKCI0.56999248
83MAP3K60.55693933
84PRKD10.54845654
85KDR0.54420919
86CHUK0.53709223
87RPS6KA40.53663961
88JAK20.53633587
89BMX0.53342947
90PDK10.52318628
91TESK20.50994806
92DMPK0.50514859
93PIK3CG0.50000943
94CDK40.49660873
95YES10.45648587
96GRK10.45563714
97FYN0.43651643
98PKN20.43647787
99MYLK0.43530433
100PDGFRB0.43513951
101TGFBR10.43360460
102MAP2K20.43013440
103DYRK1B0.42575932
104MAP3K80.41470490
105MAPK70.41422803
106MAPK120.41352419
107BMPR20.40958395
108PRKCD0.40828370
109ABL10.40755718
110CDC42BPA0.40698422
111MELK0.40214477
112EGFR0.39930936
113GRK50.38059843
114TAOK20.36647735
115TESK10.35803390
116EPHA30.35021650
117DYRK30.33341033
118STK240.33031570
119CDK60.32321412
120INSR0.32066556
121CDK90.31726644
122MAP3K70.31596642
123PTK60.31133712
124SRC0.31028595
125MARK20.29757372
126MAPK110.28933366
127MAP2K30.25493347
128SGK30.24957351
129BRD40.24881826
130BUB10.23962618
131FRK0.21838454
132MAPK40.19019387
133TTN0.18525817
134MAPKAPK20.17294659
135CDC70.17147930
136CSNK1A1L0.15630797
137BRSK10.15626074

Predicted pathways (KEGG)

RankGene SetZ-score
1Intestinal immune network for IgA production_Homo sapiens_hsa046727.13804198
2Primary immunodeficiency_Homo sapiens_hsa053406.41089847
3B cell receptor signaling pathway_Homo sapiens_hsa046625.29535339
4Autoimmune thyroid disease_Homo sapiens_hsa053203.46177090
5Graft-versus-host disease_Homo sapiens_hsa053323.31755683
6Type I diabetes mellitus_Homo sapiens_hsa049402.75945463
7NF-kappa B signaling pathway_Homo sapiens_hsa040642.74799696
8Antigen processing and presentation_Homo sapiens_hsa046122.32223511
9Osteoclast differentiation_Homo sapiens_hsa043802.14337860
10Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.09901148
11Protein export_Homo sapiens_hsa030602.02018759
12Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.01057816
13Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.99294571
14N-Glycan biosynthesis_Homo sapiens_hsa005101.84881171
15Leishmaniasis_Homo sapiens_hsa051401.75308263
16Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.75116111
17T cell receptor signaling pathway_Homo sapiens_hsa046601.74681365
18Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.71239920
19Rheumatoid arthritis_Homo sapiens_hsa053231.59154884
20Chemokine signaling pathway_Homo sapiens_hsa040621.58730430
21Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.45234835
22Hematopoietic cell lineage_Homo sapiens_hsa046401.34968379
23Leukocyte transendothelial migration_Homo sapiens_hsa046701.32333542
24Arginine biosynthesis_Homo sapiens_hsa002201.29700171
25Renin-angiotensin system_Homo sapiens_hsa046141.25250254
26Complement and coagulation cascades_Homo sapiens_hsa046101.23529841
27Systemic lupus erythematosus_Homo sapiens_hsa053221.21775011
28Tuberculosis_Homo sapiens_hsa051521.18402101
29Measles_Homo sapiens_hsa051621.15307940
30Fat digestion and absorption_Homo sapiens_hsa049751.14979191
31Non-small cell lung cancer_Homo sapiens_hsa052231.12837665
32Base excision repair_Homo sapiens_hsa034101.11730932
33Fructose and mannose metabolism_Homo sapiens_hsa000511.11519589
34Phagosome_Homo sapiens_hsa041451.09450560
35Asthma_Homo sapiens_hsa053101.06543886
36RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.95158738
37Hepatitis B_Homo sapiens_hsa051610.94873131
38Toll-like receptor signaling pathway_Homo sapiens_hsa046200.91628204
39Herpes simplex infection_Homo sapiens_hsa051680.91474052
40Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.90269127
41Neurotrophin signaling pathway_Homo sapiens_hsa047220.89963319
42Protein digestion and absorption_Homo sapiens_hsa049740.88985733
43VEGF signaling pathway_Homo sapiens_hsa043700.88330870
44Malaria_Homo sapiens_hsa051440.87814814
45Staphylococcus aureus infection_Homo sapiens_hsa051500.84967824
46Apoptosis_Homo sapiens_hsa042100.84911334
47Epstein-Barr virus infection_Homo sapiens_hsa051690.83688677
48Toxoplasmosis_Homo sapiens_hsa051450.83450445
49Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.83120179
50Shigellosis_Homo sapiens_hsa051310.82876490
51Platelet activation_Homo sapiens_hsa046110.81132360
52Pancreatic cancer_Homo sapiens_hsa052120.80294919
53Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.80234073
54Viral myocarditis_Homo sapiens_hsa054160.79999024
55Acute myeloid leukemia_Homo sapiens_hsa052210.79721254
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.79368852
57Pertussis_Homo sapiens_hsa051330.78390429
58Other glycan degradation_Homo sapiens_hsa005110.77241549
59NOD-like receptor signaling pathway_Homo sapiens_hsa046210.76721570
60alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.76623454
61Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.76489832
62Arachidonic acid metabolism_Homo sapiens_hsa005900.76051085
63DNA replication_Homo sapiens_hsa030300.75756341
64Chronic myeloid leukemia_Homo sapiens_hsa052200.74803967
65Jak-STAT signaling pathway_Homo sapiens_hsa046300.73345008
66HTLV-I infection_Homo sapiens_hsa051660.72135080
67AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.71209953
68Amoebiasis_Homo sapiens_hsa051460.71137795
69Sulfur metabolism_Homo sapiens_hsa009200.68699727
70Non-homologous end-joining_Homo sapiens_hsa034500.67728705
71Influenza A_Homo sapiens_hsa051640.65830395
72Carbohydrate digestion and absorption_Homo sapiens_hsa049730.65176350
73Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64255047
74Mismatch repair_Homo sapiens_hsa034300.61313253
75Linoleic acid metabolism_Homo sapiens_hsa005910.59290164
76Phosphatidylinositol signaling system_Homo sapiens_hsa040700.58835552
77Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.57441648
78Viral carcinogenesis_Homo sapiens_hsa052030.56842113
79Prion diseases_Homo sapiens_hsa050200.55816412
80Insulin resistance_Homo sapiens_hsa049310.55648798
81Mineral absorption_Homo sapiens_hsa049780.53721256
82Ribosome_Homo sapiens_hsa030100.52207460
83African trypanosomiasis_Homo sapiens_hsa051430.52142880
84Allograft rejection_Homo sapiens_hsa053300.52052351
85Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.51595596
86Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50321237
87Salmonella infection_Homo sapiens_hsa051320.49464039
88Inositol phosphate metabolism_Homo sapiens_hsa005620.49313876
89MAPK signaling pathway_Homo sapiens_hsa040100.48348270
90Legionellosis_Homo sapiens_hsa051340.48239078
91Lysosome_Homo sapiens_hsa041420.47178860
92Pancreatic secretion_Homo sapiens_hsa049720.45586120
93TNF signaling pathway_Homo sapiens_hsa046680.45163891
94Vitamin digestion and absorption_Homo sapiens_hsa049770.44374648
95Long-term potentiation_Homo sapiens_hsa047200.44234434
96Glioma_Homo sapiens_hsa052140.40851269
97MicroRNAs in cancer_Homo sapiens_hsa052060.40482429
98Galactose metabolism_Homo sapiens_hsa000520.40440547
99Ether lipid metabolism_Homo sapiens_hsa005650.40408732
100Glycosaminoglycan degradation_Homo sapiens_hsa005310.40120485
101PPAR signaling pathway_Homo sapiens_hsa033200.39042793
102Dorso-ventral axis formation_Homo sapiens_hsa043200.38557310
103Hepatitis C_Homo sapiens_hsa051600.38111161
104Thyroid hormone synthesis_Homo sapiens_hsa049180.37824163
105Renal cell carcinoma_Homo sapiens_hsa052110.37471331
106Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.35509734
107Aldosterone synthesis and secretion_Homo sapiens_hsa049250.34730096
108Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.34238564
109Adipocytokine signaling pathway_Homo sapiens_hsa049200.33583526
110Small cell lung cancer_Homo sapiens_hsa052220.33042914
111HIF-1 signaling pathway_Homo sapiens_hsa040660.32583291
112FoxO signaling pathway_Homo sapiens_hsa040680.31781176
113GnRH signaling pathway_Homo sapiens_hsa049120.31286248
114Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.30221347
115Cyanoamino acid metabolism_Homo sapiens_hsa004600.30130216
116Drug metabolism - other enzymes_Homo sapiens_hsa009830.29881718
117Caffeine metabolism_Homo sapiens_hsa002320.29714357
118Estrogen signaling pathway_Homo sapiens_hsa049150.29652596
119Histidine metabolism_Homo sapiens_hsa003400.29630592
120p53 signaling pathway_Homo sapiens_hsa041150.28744590
121Endocytosis_Homo sapiens_hsa041440.28492325
122Notch signaling pathway_Homo sapiens_hsa043300.27886349
123Prolactin signaling pathway_Homo sapiens_hsa049170.26597681
124Starch and sucrose metabolism_Homo sapiens_hsa005000.26189694
125Prostate cancer_Homo sapiens_hsa052150.25896431
126Phospholipase D signaling pathway_Homo sapiens_hsa040720.25688612
127Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.25388599
128Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.25345615
129Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.25341001
130Transcriptional misregulation in cancer_Homo sapiens_hsa052020.24346684
131Glycerolipid metabolism_Homo sapiens_hsa005610.24222165
132Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.24065638
133Glucagon signaling pathway_Homo sapiens_hsa049220.21793279
134ABC transporters_Homo sapiens_hsa020100.21709279
135cGMP-PKG signaling pathway_Homo sapiens_hsa040220.20952894
136Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.20553747
137Proteoglycans in cancer_Homo sapiens_hsa052050.19711968
138Amphetamine addiction_Homo sapiens_hsa050310.19340371
139Colorectal cancer_Homo sapiens_hsa052100.19183299
140Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.18277633

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