IGKC

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous antigen (GO:0019883)9.26282543
2positive regulation of respiratory burst (GO:0060267)8.77764684
3* complement activation, classical pathway (GO:0006958)8.49974292
4B cell receptor signaling pathway (GO:0050853)7.92305951
5antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)7.69058922
6antigen processing and presentation of endogenous peptide antigen (GO:0002483)7.69058922
7glomerular filtration (GO:0003094)7.37799816
8renal filtration (GO:0097205)6.64913288
9* complement activation (GO:0006956)6.40347095
10negative regulation of B cell proliferation (GO:0030889)6.26675863
11regulation of B cell receptor signaling pathway (GO:0050855)6.07097551
12regulation of respiratory burst (GO:0060263)5.97362236
13cellular response to zinc ion (GO:0071294)5.93229733
14regulation of B cell differentiation (GO:0045577)5.59759222
15positive regulation of B cell differentiation (GO:0045579)5.56327530
16positive regulation of gamma-delta T cell activation (GO:0046645)5.42856098
17regulation of B cell proliferation (GO:0030888)5.31634207
18negative regulation of glucose import (GO:0046325)5.19953749
19* Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096)5.08818321
20* immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:00025.08818321
21* Fc-gamma receptor signaling pathway (GO:0038094)5.08818321
22* Fc receptor mediated stimulatory signaling pathway (GO:0002431)5.01129101
23mature B cell differentiation (GO:0002335)4.97460658
24cytidine metabolic process (GO:0046087)4.97201912
25cytidine catabolic process (GO:0006216)4.97201912
26cytidine deamination (GO:0009972)4.97201912
27antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.83067688
28regulation of dendritic cell antigen processing and presentation (GO:0002604)4.76366255
29regulation of cellular extravasation (GO:0002691)4.62537921
30* humoral immune response (GO:0006959)4.47445603
31B cell proliferation (GO:0042100)4.44129652
32regulation of gamma-delta T cell differentiation (GO:0045586)4.42252081
33regulation of glucose import in response to insulin stimulus (GO:2001273)4.34012881
34* immune response-activating cell surface receptor signaling pathway (GO:0002429)4.31738701
35negative regulation of glucose transport (GO:0010829)4.30973510
36positive thymic T cell selection (GO:0045059)4.24724828
37regulation of antigen processing and presentation (GO:0002577)4.20395110
38detection of bacterium (GO:0016045)4.20234651
39regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.18038439
40mature B cell differentiation involved in immune response (GO:0002313)4.11592157
41positive regulation of immunoglobulin production (GO:0002639)4.08038751
42regulation of B cell apoptotic process (GO:0002902)4.06351553
43detection of other organism (GO:0098543)4.02590641
44positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.01900925
45* protein activation cascade (GO:0072376)3.98728461
46regulation of gamma-delta T cell activation (GO:0046643)3.98185523
47regulation of interferon-beta biosynthetic process (GO:0045357)3.90493788
48positive regulation of Rap GTPase activity (GO:0032854)3.89780275
49response to type I interferon (GO:0034340)3.88845754
50type I interferon signaling pathway (GO:0060337)3.87695374
51cellular response to type I interferon (GO:0071357)3.87695374
52signal peptide processing (GO:0006465)3.86134629
53antigen receptor-mediated signaling pathway (GO:0050851)3.85316667
54regulation of B cell activation (GO:0050864)3.85218207
55positive regulation of pseudopodium assembly (GO:0031274)3.80928825
56negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.76498174
57negative regulation of cell killing (GO:0031342)3.76498174
58pyrimidine ribonucleoside catabolic process (GO:0046133)3.76413933
59B cell homeostasis (GO:0001782)3.72051953
60regulation of interleukin-12 biosynthetic process (GO:0045075)3.69797174
61regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.69607389
62negative thymic T cell selection (GO:0045060)3.65717482
63somatic diversification of immune receptors via somatic mutation (GO:0002566)3.62032920
64somatic hypermutation of immunoglobulin genes (GO:0016446)3.62032920
65regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022353.55441641
66response to interleukin-15 (GO:0070672)3.54090909
67negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.53267782
68respiratory burst (GO:0045730)3.52898503
69thymic T cell selection (GO:0045061)3.49772216
70germinal center formation (GO:0002467)3.49526508
71positive regulation of Cdc42 GTPase activity (GO:0043089)3.49101886
72B cell activation (GO:0042113)3.48354971
73negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.45280566
74regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.43983559
75immunoglobulin mediated immune response (GO:0016064)3.41889680
76negative regulation of B cell apoptotic process (GO:0002903)3.41782035
77regulation of pseudopodium assembly (GO:0031272)3.39600579
78positive regulation of B cell proliferation (GO:0030890)3.36900185
79defense response to protozoan (GO:0042832)3.35215556
80negative T cell selection (GO:0043383)3.33157971
81cellular response to interferon-gamma (GO:0071346)3.31779936
82positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.31744135
83angiotensin maturation (GO:0002003)3.31326539
84antimicrobial humoral response (GO:0019730)3.30563997
85lymphocyte homeostasis (GO:0002260)3.29305773
86positive regulation of B cell activation (GO:0050871)3.27939654
87NIK/NF-kappaB signaling (GO:0038061)3.25288954
88negative regulation of B cell activation (GO:0050869)3.24382142
89B cell mediated immunity (GO:0019724)3.24256160
90T cell selection (GO:0045058)3.24135362
91regulation of immunoglobulin production (GO:0002637)3.18823864
92chronic inflammatory response (GO:0002544)3.18180085
93regulation of Rap GTPase activity (GO:0032317)3.17342074
94negative regulation of phagocytosis (GO:0050765)3.17262101
95* immune response-activating signal transduction (GO:0002757)3.15500440
96cellular response to interleukin-15 (GO:0071350)3.15342233
97interferon-gamma-mediated signaling pathway (GO:0060333)3.14289786
98antibacterial humoral response (GO:0019731)3.13638209
99response to interferon-gamma (GO:0034341)3.13609811
100regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)3.10386640
101lymph node development (GO:0048535)3.07518694
102regulation of superoxide anion generation (GO:0032928)3.03850357
103myeloid dendritic cell differentiation (GO:0043011)3.01690115
104regulation of alpha-beta T cell proliferation (GO:0046640)2.98698334
105detection of external biotic stimulus (GO:0098581)2.97778512
106T cell costimulation (GO:0031295)2.96281490
107response to protozoan (GO:0001562)2.95813638
108T-helper 1 type immune response (GO:0042088)2.93391884
109lymphocyte costimulation (GO:0031294)2.92506194
110dendritic cell chemotaxis (GO:0002407)2.91952547
111B cell differentiation (GO:0030183)2.90111819
112leukocyte homeostasis (GO:0001776)2.90011886
113ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)2.88864687
114regulation of interferon-alpha production (GO:0032647)2.88684280
115positive regulation of histone deacetylation (GO:0031065)2.88324200
116positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.86626300
117positive T cell selection (GO:0043368)2.85531243
118* activation of immune response (GO:0002253)2.83848914
119surfactant homeostasis (GO:0043129)2.83816835
120myeloid dendritic cell activation (GO:0001773)2.83096308
121* retina homeostasis (GO:0001895)2.83074506
122regulation of integrin activation (GO:0033623)2.82279028
123regulation of T cell tolerance induction (GO:0002664)2.81920633
124mononuclear cell proliferation (GO:0032943)2.81265144
125chaperone mediated protein folding requiring cofactor (GO:0051085)2.81156097
126positive regulation of production of molecular mediator of immune response (GO:0002702)2.80943488
127positive regulation of antigen processing and presentation (GO:0002579)2.80585028
128positive regulation of interleukin-2 production (GO:0032743)2.80278604
129regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.77893308
130positive regulation of granulocyte chemotaxis (GO:0071624)2.77545486
131lymphocyte proliferation (GO:0046651)2.76685329
132positive regulation of gene expression, epigenetic (GO:0045815)2.74721058
133antigen processing and presentation via MHC class Ib (GO:0002475)2.73739983
134production of molecular mediator of immune response (GO:0002440)2.73328588
135B cell activation involved in immune response (GO:0002312)2.73295967
136natural killer cell mediated cytotoxicity (GO:0042267)2.72162755
137positive regulation of T cell migration (GO:2000406)2.71251011
138regulation of type I interferon-mediated signaling pathway (GO:0060338)2.69268642
139eosinophil chemotaxis (GO:0048245)2.69088627
140GDP-mannose metabolic process (GO:0019673)2.66825655
141regulation of T cell migration (GO:2000404)2.65350547
142positive regulation of neutrophil chemotaxis (GO:0090023)2.62269420
143positive regulation of neutrophil migration (GO:1902624)2.62269420
144peptide catabolic process (GO:0043171)2.60861301
145negative regulation of myotube differentiation (GO:0010832)2.60780308
146protein-chromophore linkage (GO:0018298)2.60572557
147regulation of regulatory T cell differentiation (GO:0045589)2.49386428
148regulation of necrotic cell death (GO:0010939)2.48345367
149regulation of tolerance induction (GO:0002643)2.48148597
150detection of biotic stimulus (GO:0009595)2.47742819
151response to interferon-beta (GO:0035456)2.46924883
152positive regulation of lymphocyte migration (GO:2000403)2.45618061
153eosinophil migration (GO:0072677)2.45231333
154adhesion of symbiont to host cell (GO:0044650)2.43669183
155virion attachment to host cell (GO:0019062)2.43669183
156dendritic cell migration (GO:0036336)2.42429145
157regulation of T-helper 1 cell differentiation (GO:0045625)2.41440524
158defense response to Gram-negative bacterium (GO:0050829)2.39860269
159interferon-gamma secretion (GO:0072643)2.39737769
160maintenance of gastrointestinal epithelium (GO:0030277)2.39563831
161negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.36509916
162regulation of lymphocyte migration (GO:2000401)2.35781654
163adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.32735719
164positive regulation of lipid kinase activity (GO:0090218)2.32126311
165dendritic cell differentiation (GO:0097028)2.31315238
166intestinal absorption (GO:0050892)2.30202661
167regulation of guanylate cyclase activity (GO:0031282)2.29774721

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.29529237
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.11871293
3MYC_22102868_ChIP-Seq_BL_Human4.74553210
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.67898944
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.41730836
6TP63_17297297_ChIP-ChIP_HaCaT_Human4.05480009
7SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.83829390
8IRF8_21731497_ChIP-ChIP_J774_Mouse3.73139530
9STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.63747051
10EGR1_19374776_ChIP-ChIP_THP-1_Human3.31335706
11E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human3.24385758
12VDR_21846776_ChIP-Seq_THP-1_Human3.21629438
13E2F7_22180533_ChIP-Seq_HELA_Human3.18123184
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.02665584
15CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.91502399
16IRF8_27001747_Chip-Seq_BMDM_Mouse2.77663247
17MAF_26560356_Chip-Seq_TH1_Human2.72050759
18RUNX_20019798_ChIP-Seq_JUKART_Human2.70525903
19MYB_26560356_Chip-Seq_TH2_Human2.55464980
20FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.52644867
21MYB_26560356_Chip-Seq_TH1_Human2.48103706
22UTX_26944678_Chip-Seq_JUKART_Human2.20448910
23VDR_24763502_ChIP-Seq_THP-1_Human2.18529258
24STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.14435797
25SCL_19346495_ChIP-Seq_HPC-7_Human2.13964906
26NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.13610425
27NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.12289252
28SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.10794788
29NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.09346365
30STAT4_19710469_ChIP-ChIP_TH1__Mouse2.08296813
31IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.08225663
32SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.04377339
33TCF7_22412390_ChIP-Seq_EML_Mouse2.00259128
34CDX2_20551321_ChIP-Seq_CACO-2_Human1.99210878
35SPI1_23547873_ChIP-Seq_NB4_Human1.95065300
36KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.87876882
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.81967772
38CIITA_25753668_ChIP-Seq_RAJI_Human1.79585734
39BRD4_27068464_Chip-Seq_AML-cells_Mouse1.77756322
40TRIM28_21343339_ChIP-Seq_HEK293_Human1.75963053
41STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.74476661
42RUNX1_22412390_ChIP-Seq_EML_Mouse1.71447233
43SOX2_27498859_Chip-Seq_STOMACH_Mouse1.69750732
44RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.68129207
45KDM2B_26808549_Chip-Seq_DND41_Human1.67609173
46KDM2B_26808549_Chip-Seq_SUP-B15_Human1.66124782
47MAF_26560356_Chip-Seq_TH2_Human1.64980320
48EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.64528031
49GATA1_22025678_ChIP-Seq_K562_Human1.61901691
50FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.60830608
51MYB_21317192_ChIP-Seq_ERMYB_Mouse1.60527052
52* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.60230153
53SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.59443107
54SPI1_23127762_ChIP-Seq_K562_Human1.53806211
55RARG_19884340_ChIP-ChIP_MEFs_Mouse1.53070498
56BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.52464700
57GATA3_27048872_Chip-Seq_THYMUS_Human1.51249279
58FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.50511365
59VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.49942763
60PU.1_20513432_ChIP-Seq_Bcells_Mouse1.49077774
61NOTCH1_21737748_ChIP-Seq_TLL_Human1.47536650
62PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.46728342
63ELK3_25401928_ChIP-Seq_HUVEC_Human1.45911901
64CLOCK_20551151_ChIP-Seq_293T_Human1.44723144
65GATA2_22383799_ChIP-Seq_G1ME_Mouse1.43157226
66KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.42833298
67TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.40778267
68SMAD_19615063_ChIP-ChIP_OVARY_Human1.39591756
69GATA1_22383799_ChIP-Seq_G1ME_Mouse1.39029532
70FOXM1_23109430_ChIP-Seq_U2OS_Human1.37481570
71MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.33282653
72TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.32683002
73SOX2_20726797_ChIP-Seq_SW620_Human1.32645536
74TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32511650
75SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.30606959
76RACK7_27058665_Chip-Seq_MCF-7_Human1.28956197
77TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.27725800
78PPARA_22158963_ChIP-Seq_LIVER_Mouse1.27181899
79ELF1_17652178_ChIP-ChIP_JURKAT_Human1.26902415
80EGR1_19032775_ChIP-ChIP_M12_Human1.25520507
81MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25340011
82ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.21780439
83TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.21600805
84P63_26484246_Chip-Seq_KERATINOCYTES_Human1.20587435
85RXR_22158963_ChIP-Seq_LIVER_Mouse1.18568685
86ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.18261232
87LXR_22292898_ChIP-Seq_THP-1_Human1.16354259
88GATA4_25053715_ChIP-Seq_YYC3_Human1.16178352
89ESR2_21235772_ChIP-Seq_MCF-7_Human1.11404469
90GATA3_26560356_Chip-Seq_TH2_Human1.10932344
91FOXO3_23340844_ChIP-Seq_DLD1_Human1.10727333
92GATA6_25053715_ChIP-Seq_YYC3_Human1.10610845
93LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.10105263
94Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.09585478
95KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.08131345
96FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.03793713
97CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02764752
98THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.01868333
99KDM5A_27292631_Chip-Seq_BREAST_Human1.01479587
100CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.99161117
101DNAJC2_21179169_ChIP-ChIP_NT2_Human0.98886704
102VDR_24787735_ChIP-Seq_THP-1_Human0.98510382
103LXR_22158963_ChIP-Seq_LIVER_Mouse0.98033368
104ERG_20887958_ChIP-Seq_HPC-7_Mouse0.97326084
105TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.96834196
106PU_27001747_Chip-Seq_BMDM_Mouse0.96755390
107NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.96406608
108FOXP3_21729870_ChIP-Seq_TREG_Human0.95733218
109GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.95156309
110CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.95047788
111NCOR1_26117541_ChIP-Seq_K562_Human0.94794069
112IKZF1_21737484_ChIP-ChIP_HCT116_Human0.93289553
113P300_27268052_Chip-Seq_Bcells_Human0.92913854
114GATA1_19941827_ChIP-Seq_MEL_Mouse0.92561537
115GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.92245103
116PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.91480805
117BCL6_27268052_Chip-Seq_Bcells_Human0.89222472
118BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.88861758
119CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87813013
120PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86698977
121RUNX1_27514584_Chip-Seq_MCF-7_Human0.86687700
122GATA2_19941826_ChIP-Seq_K562_Human0.86543556
123LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.84428742
124SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.83406358
125PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.83096114
126KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.82660553
127HOXB4_20404135_ChIP-ChIP_EML_Mouse0.82321432
128ELF1_20517297_ChIP-Seq_JURKAT_Human0.81398596
129NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.81359965
130CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.80694434
131VDR_23849224_ChIP-Seq_CD4+_Human0.80161429
132SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.79224159
133CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.79010840
134SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.78730467
135RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78511973
136KDM2B_26808549_Chip-Seq_JURKAT_Human0.76695094
137CTCF_26484167_Chip-Seq_Bcells_Mouse0.75181309
138CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.74047213
139CTCF_27219007_Chip-Seq_ERYTHROID_Human0.73632111
140GATA1_19941826_ChIP-Seq_K562_Human0.72905895
141BCOR_27268052_Chip-Seq_Bcells_Human0.72762793

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation6.05552880
2MP0005387_immune_system_phenotype4.73040454
3MP0001790_abnormal_immune_system4.73040454
4* MP0001800_abnormal_humoral_immune4.68492646
5MP0003303_peritoneal_inflammation4.36478404
6MP0003724_increased_susceptibility_to4.08263225
7* MP0002452_abnormal_antigen_presenting3.56952193
8MP0005671_abnormal_response_to3.39078483
9MP0000685_abnormal_immune_system3.26393860
10MP0005000_abnormal_immune_tolerance3.08200439
11* MP0002723_abnormal_immune_serum3.00731099
12* MP0002420_abnormal_adaptive_immunity2.95438507
13* MP0001819_abnormal_immune_cell2.88080567
14MP0003300_gastrointestinal_ulcer2.80084946
15* MP0002398_abnormal_bone_marrow2.74073310
16* MP0000716_abnormal_immune_system2.57201306
17* MP0000689_abnormal_spleen_morphology2.40197294
18MP0005025_abnormal_response_to2.36798942
19MP0003763_abnormal_thymus_physiology2.35596406
20MP0010234_abnormal_vibrissa_follicle2.17157902
21MP0002148_abnormal_hypersensitivity_rea2.16557519
22MP0001873_stomach_inflammation2.15100012
23* MP0002429_abnormal_blood_cell2.13477038
24MP0002166_altered_tumor_susceptibility2.10551475
25MP0001879_abnormal_lymphatic_vessel2.07605733
26* MP0002722_abnormal_immune_system2.00312345
27MP0010155_abnormal_intestine_physiology1.98494092
28MP0005275_abnormal_skin_tensile1.95796953
29MP0003436_decreased_susceptibility_to1.95550963
30MP0002419_abnormal_innate_immunity1.92121512
31MP0005166_decreased_susceptibility_to1.91202518
32MP0004782_abnormal_surfactant_physiolog1.86630434
33MP0009785_altered_susceptibility_to1.84836920
34MP0001845_abnormal_inflammatory_respons1.82974373
35MP0002139_abnormal_hepatobiliary_system1.81626698
36MP0003866_abnormal_defecation1.71618723
37MP0002405_respiratory_system_inflammati1.71578908
38MP0005310_abnormal_salivary_gland1.64025297
39MP0004947_skin_inflammation1.62558398
40MP0009333_abnormal_splenocyte_physiolog1.61371882
41MP0001853_heart_inflammation1.60986811
42MP0004510_myositis1.57509378
43MP0002396_abnormal_hematopoietic_system1.54576733
44MP0002796_impaired_skin_barrier1.51144011
45MP0002933_joint_inflammation1.49067048
46MP0006054_spinal_hemorrhage1.47427285
47MP0004858_abnormal_nervous_system1.47075806
48MP0004264_abnormal_extraembryonic_tissu1.46127973
49MP0000703_abnormal_thymus_morphology1.45619364
50MP0002006_tumorigenesis1.42524946
51MP0000465_gastrointestinal_hemorrhage1.37294243
52MP0009840_abnormal_foam_cell1.32539234
53MP0004808_abnormal_hematopoietic_stem1.31611099
54MP0005464_abnormal_platelet_physiology1.30280828
55MP0008004_abnormal_stomach_pH1.24320539
56MP0003183_abnormal_peptide_metabolism1.24028784
57MP0001666_abnormal_nutrient_absorption1.22571051
58MP0000490_abnormal_crypts_of1.22471248
59MP0005360_urolithiasis1.19711968
60MP0003075_altered_response_to1.19383139
61MP0008438_abnormal_cutaneous_collagen1.12358315
62MP0003453_abnormal_keratinocyte_physiol1.11275356
63MP0002019_abnormal_tumor_incidence1.08811645
64MP0000343_altered_response_to1.08000646
65MP0005503_abnormal_tendon_morphology1.05821490
66MP0002136_abnormal_kidney_physiology1.04974183
67MP0000604_amyloidosis1.04911520
68MP0001663_abnormal_digestive_system1.01595005
69MP0001851_eye_inflammation1.01245714
70MP0003045_fibrosis1.01004856
71MP0010352_gastrointestinal_tract_polyps0.98979430
72MP0006082_CNS_inflammation0.95227196
73MP0008469_abnormal_protein_level0.94330682
74MP0005085_abnormal_gallbladder_physiolo0.93288432
75MP0002277_abnormal_respiratory_mucosa0.92616489
76MP0003693_abnormal_embryo_hatching0.92388393
77MP0005390_skeleton_phenotype0.91679612
78MP0005058_abnormal_lysosome_morphology0.91203289
79MP0001958_emphysema0.89933461
80MP0003279_aneurysm0.88585286
81MP0001664_abnormal_digestion0.87604979
82MP0005451_abnormal_body_composition0.87109746
83MP0003868_abnormal_feces_composition0.86714866
84MP0001216_abnormal_epidermal_layer0.84629342
85MP0005409_darkened_coat_color0.84107708
86MP0005397_hematopoietic_system_phenotyp0.82000705
87MP0001545_abnormal_hematopoietic_system0.82000705
88MP0005076_abnormal_cell_differentiation0.80848120
89MP0002138_abnormal_hepatobiliary_system0.80415256
90MP0003329_amyloid_beta_deposits0.80348040
91MP0005164_abnormal_response_to0.76770521
92MP0001533_abnormal_skeleton_physiology0.76508570
93MP0005165_increased_susceptibility_to0.75372305
94MP0005388_respiratory_system_phenotype0.74957285
95MP0002133_abnormal_respiratory_system0.74957285
96MP0008260_abnormal_autophagy0.74206622
97MP0000681_abnormal_thyroid_gland0.73042322
98MP0000477_abnormal_intestine_morphology0.72470522
99MP0008961_abnormal_basal_metabolism0.72378271
100MP0002876_abnormal_thyroid_physiology0.72120338
101MP0003795_abnormal_bone_structure0.70808357
102MP0003191_abnormal_cellular_cholesterol0.67098562
103MP0009278_abnormal_bone_marrow0.66711116
104MP0005584_abnormal_enzyme/coenzyme_acti0.66493515
105MP0003077_abnormal_cell_cycle0.66337225
106MP0001191_abnormal_skin_condition0.65768934
107MP0002693_abnormal_pancreas_physiology0.65354232
108MP0000609_abnormal_liver_physiology0.63663820
109MP0005174_abnormal_tail_pigmentation0.63162419
110MP0003091_abnormal_cell_migration0.61933920
111MP0003566_abnormal_cell_adhesion0.61268091
112MP0002168_other_aberrant_phenotype0.60804401
113MP0005381_digestive/alimentary_phenotyp0.59523619
114MP0003943_abnormal_hepatobiliary_system0.59094181
115MP0008057_abnormal_DNA_replication0.58688210
116MP0000003_abnormal_adipose_tissue0.58359759
117MP0009643_abnormal_urine_homeostasis0.57131208
118MP0005023_abnormal_wound_healing0.57066339
119MP0000249_abnormal_blood_vessel0.52917299
120MP0000858_altered_metastatic_potential0.52614504
121MP0003828_pulmonary_edema0.50887582
122MP0002928_abnormal_bile_duct0.50235955
123MP0010094_abnormal_chromosome_stability0.49666383
124MP0002083_premature_death0.49097582
125MP0002909_abnormal_adrenal_gland0.47717551
126MP0001919_abnormal_reproductive_system0.47500095
127MP0000013_abnormal_adipose_tissue0.47474934
128MP0009931_abnormal_skin_appearance0.47386826
129MP0000350_abnormal_cell_proliferation0.47088115
130MP0003448_altered_tumor_morphology0.46647557
131MP0000733_abnormal_muscle_development0.46615999
132MP0003656_abnormal_erythrocyte_physiolo0.46381008
133MP0000313_abnormal_cell_death0.45936633
134MP0005621_abnormal_cell_physiology0.45022866
135MP0009764_decreased_sensitivity_to0.44653328
136MP0009763_increased_sensitivity_to0.42638500
137MP0002998_abnormal_bone_remodeling0.42625229
138MP0001944_abnormal_pancreas_morphology0.41385436

Predicted human phenotypes

RankGene SetZ-score
1Colitis (HP:0002583)7.34339523
2Recurrent bronchitis (HP:0002837)7.23785120
3Recurrent sinusitis (HP:0011108)7.11512815
4Cellulitis (HP:0100658)6.79562411
5Gastrointestinal stroma tumor (HP:0100723)6.61876784
6Systemic lupus erythematosus (HP:0002725)6.45191390
7Abnormality of B cell number (HP:0010975)6.40021911
8B lymphocytopenia (HP:0010976)6.40021911
9Papilloma (HP:0012740)5.94301552
10Verrucae (HP:0200043)5.94301552
11Inflammation of the large intestine (HP:0002037)5.91302349
12IgM deficiency (HP:0002850)5.84743928
13Gastrointestinal inflammation (HP:0004386)5.67818220
14Recurrent viral infections (HP:0004429)5.30656638
15Meningitis (HP:0001287)5.04009172
16Chronic sinusitis (HP:0011109)4.74047352
17Chronic otitis media (HP:0000389)4.72611598
18Recurrent pneumonia (HP:0006532)4.67374653
19Malnutrition (HP:0004395)4.56667010
20Recurrent lower respiratory tract infections (HP:0002783)4.32376161
21Bronchitis (HP:0012387)4.31557404
22Emphysema (HP:0002097)4.30289198
23Osteomyelitis (HP:0002754)4.18812444
24Abnormality of complement system (HP:0005339)4.15445952
25Glomerulonephritis (HP:0000099)3.96481286
26Recurrent otitis media (HP:0000403)3.92866380
27Lymphopenia (HP:0001888)3.88459201
28Abnormal delayed hypersensitivity skin test (HP:0002963)3.87707424
29Complement deficiency (HP:0004431)3.84979771
30Prostate neoplasm (HP:0100787)3.84431445
31IgA deficiency (HP:0002720)3.80965737
32Abnormality of cells of the lymphoid lineage (HP:0012140)3.72590839
33Panhypogammaglobulinemia (HP:0003139)3.69478708
34Vasculitis (HP:0002633)3.65187266
35Interstitial pulmonary disease (HP:0006530)3.65080887
36Sepsis (HP:0100806)3.36736918
37Restrictive lung disease (HP:0002091)3.33437081
38Nephritis (HP:0000123)3.32519056
39Abnormality of T cell physiology (HP:0011840)3.30202643
40Recurrent abscess formation (HP:0002722)3.24574056
41IgG deficiency (HP:0004315)3.22526485
42Abnormality of the prostate (HP:0008775)3.17040046
43Skin rash (HP:0000988)3.16810083
44Recurrent bacterial skin infections (HP:0005406)3.07459488
45Nasal polyposis (HP:0100582)3.07130988
46Recurrent fungal infections (HP:0002841)2.98785403
47Premature loss of primary teeth (HP:0006323)2.87486498
48Gastrointestinal infarctions (HP:0005244)2.85826835
49Alopecia of scalp (HP:0002293)2.85335093
50Abnormality of T cells (HP:0002843)2.81467635
51Thyroiditis (HP:0100646)2.80085340
52Eczematoid dermatitis (HP:0000976)2.72628569
53Abnormality of the nasal mucosa (HP:0000433)2.72380705
54Autoimmune thrombocytopenia (HP:0001973)2.70634000
55Gingivitis (HP:0000230)2.69979545
56Thrombocytosis (HP:0001894)2.66568654
57Elevated erythrocyte sedimentation rate (HP:0003565)2.66081023
58Recurrent cutaneous fungal infections (HP:0011370)2.61185272
59Chronic mucocutaneous candidiasis (HP:0002728)2.61185272
60Hyperactive renin-angiotensin system (HP:0000841)2.59607550
61Recurrent skin infections (HP:0001581)2.54667260
62Hemoptysis (HP:0002105)2.51629616
63Mediastinal lymphadenopathy (HP:0100721)2.49173354
64Myositis (HP:0100614)2.48627977
65Abnormality of glutamine family amino acid metabolism (HP:0010902)2.46836771
66Small epiphyses (HP:0010585)2.44641149
67Basal cell carcinoma (HP:0002671)2.42304586
68Skin ulcer (HP:0200042)2.38741955
69Viral hepatitis (HP:0006562)2.36674146
70Xerostomia (HP:0000217)2.35582997
71Leukopenia (HP:0001882)2.35333262
72Mitral stenosis (HP:0001718)2.33690185
73Neutropenia (HP:0001875)2.33627848
74Bronchiectasis (HP:0002110)2.30419778
75Pulmonary infiltrates (HP:0002113)2.29620985
76Orchitis (HP:0100796)2.29522698
77Decreased circulating renin level (HP:0003351)2.28762165
78Leukocytosis (HP:0001974)2.28609990
79Pustule (HP:0200039)2.26128360
80Abnormality of the fingertips (HP:0001211)2.22598652
81Increased IgE level (HP:0003212)2.22418499
82Obstructive lung disease (HP:0006536)2.22004970
83Chronic obstructive pulmonary disease (HP:0006510)2.22004970
84Lymphoma (HP:0002665)2.21982985
85Right ventricular cardiomyopathy (HP:0011663)2.19953938
86Abnormality of monocarboxylic acid metabolism (HP:0010996)2.18650381
87Abnormality of T cell number (HP:0011839)2.11455270
88Purpura (HP:0000979)2.11414748
89Abnormal hair laboratory examination (HP:0003328)2.10229111
90Encephalitis (HP:0002383)2.10126186
91Urticaria (HP:0001025)2.09438888
92T lymphocytopenia (HP:0005403)2.07569396
93Thick nail (HP:0001805)2.04701641
94Autoimmune hemolytic anemia (HP:0001890)2.02319920
95Agammaglobulinemia (HP:0004432)10.0681892
96Erythema (HP:0010783)1.97860999
97Arthralgia (HP:0002829)1.95168595
98Recurrent gram-negative bacterial infections (HP:0005420)1.93814012
99Fatigue (HP:0012378)1.91187067
100Polygenic inheritance (HP:0010982)1.90219767
101Abnormality of the peritoneum (HP:0002585)1.89215580
102Onycholysis (HP:0001806)1.89048428
103Ileus (HP:0002595)1.88754664
104Chronic diarrhea (HP:0002028)1.87698832
105Spontaneous hematomas (HP:0007420)1.87455479
106Abnormality of the pleura (HP:0002103)1.87256591
107Increased IgM level (HP:0003496)1.86707860
108Dehydration (HP:0001944)1.86119558
109Palmoplantar hyperkeratosis (HP:0000972)1.84338437
110Pili torti (HP:0003777)1.83802117
111Hematochezia (HP:0002573)1.82732144
112Flattened epiphyses (HP:0003071)1.78398564
113Squamous cell carcinoma (HP:0002860)1.75002368
114Abnormality of macrophages (HP:0004311)1.74788457
115Petechiae (HP:0000967)1.69157184
116Chest pain (HP:0100749)1.64752558
117Teleangiectasia of the skin (HP:0100585)1.61516154
118Acrocyanosis (HP:0001063)1.60813328
119Combined immunodeficiency (HP:0005387)1.60352480
120Hypergammaglobulinemia (HP:0010702)1.58468928
121Abnormality of small intestinal villus morphology (HP:0011472)1.58383133
122Villous atrophy (HP:0011473)1.58383133
123Hypoplasia of the capital femoral epiphysis (HP:0003090)1.54481009
124Hepatitis (HP:0012115)1.54380332
125Arterial thrombosis (HP:0004420)1.54083836
126Myocardial infarction (HP:0001658)1.53031983
127Optic neuritis (HP:0100653)1.49986574
128Retrobulbar optic neuritis (HP:0100654)1.49986574
129Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.48775120
130Irregular vertebral endplates (HP:0003301)1.48668064
131Papilledema (HP:0001085)1.46473398
132Ulnar bowing (HP:0003031)1.45316820

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K16.90810260
2ERN15.51868046
3GRK63.32723573
4CSF1R2.99697088
5MST1R2.97019596
6BLK2.80088835
7SYK2.73036012
8MAP3K102.62272611
9PRPF4B2.48726999
10TYK22.25091844
11RIPK42.23495815
12MAP3K142.22159631
13TBK12.15169423
14BTK2.14067495
15MAP3K132.13587618
16LRRK21.95495358
17KIT1.85966049
18STK101.83598184
19EEF2K1.70592751
20IRAK31.67804323
21NME21.61392606
22SIK21.59696801
23LYN1.54209384
24ACVR1B1.48356366
25JAK11.46216639
26IKBKE1.45410737
27JAK31.40455066
28IRAK41.39312169
29MST41.36099384
30PRKCH1.33042421
31IKBKB1.31662479
32MAP3K11.24949512
33TGFBR21.23353908
34HCK1.22576172
35PIK3CA1.21955423
36TRIB31.16559513
37ITK1.16180139
38EPHA21.15601413
39ZAP701.15352211
40CSK1.13705902
41IRAK11.13515436
42SMG11.13240477
43TAOK31.08999226
44TGFBR11.08252600
45EIF2AK31.06175509
46FES1.05224518
47SIK31.02449502
48PRKCQ1.02108363
49LCK1.02076030
50TEC1.01303089
51STK241.00430163
52TAOK10.97463051
53PRKG20.92253252
54PIM10.91460688
55MATK0.91148308
56CDK120.91113078
57SIK10.89580575
58GRK10.88822558
59EPHB20.87546151
60DDR20.87282126
61MET0.86667630
62PDGFRA0.86529689
63HIPK20.86189112
64FGFR30.83318379
65CLK10.82406506
66FER0.82277618
67EPHB10.81643286
68MARK30.81176121
69FGFR40.79351124
70NEK20.78034492
71RPS6KA40.75506517
72CHUK0.74481814
73BMPR20.73369580
74ALK0.72668477
75MAP2K30.67448110
76MAP3K90.66751244
77DMPK0.66625045
78PRKD20.66258599
79MAP3K30.65091084
80PDPK10.62316343
81RET0.61555994
82MAP3K110.59985234
83MAP2K20.59253860
84TXK0.56676360
85PRKCI0.56123996
86MYLK0.55691830
87PDK10.53517408
88MAP3K60.53410543
89CDK40.51061443
90PTK60.48201195
91MAP3K70.47300150
92PAK40.46930724
93CDC42BPA0.46184558
94FRK0.44476068
95FYN0.44275050
96YES10.42341553
97ABL10.42200882
98BMX0.42006785
99BRD40.41930885
100TNK20.41530703
101CDK90.40877058
102PRKD10.40520428
103PKN20.40096293
104LMTK20.39488178
105CDK60.38918911
106MAPK70.38262050
107INSR0.37560294
108NEK90.36824123
109JAK20.35680495
110MAPK120.35356390
111PRKCD0.34819782
112TESK10.34589440
113MAP3K80.32995232
114PDK20.32748238
115MAPKAPK30.32090316
116FGR0.32014820
117EGFR0.31232019
118TESK20.30494041
119PIK3CG0.30307315
120PDGFRB0.30060882
121MAPK110.29986646
122KDR0.29600857
123EIF2AK10.29515075
124MAP3K20.29233415
125TAOK20.29110670
126CDK190.28968528
127RIPK10.27671939
128FLT30.27037526
129TTN0.26804597
130MAPK40.26494924
131MAPKAPK20.23926438
132MELK0.23891847
133KSR20.22918122
134NLK0.19800495
135RPS6KB20.18540704
136BCKDK0.18231133
137EPHA30.17580877
138SCYL20.17510821

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053406.43534815
2B cell receptor signaling pathway_Homo sapiens_hsa046625.54508875
3Intestinal immune network for IgA production_Homo sapiens_hsa046725.49148123
4Graft-versus-host disease_Homo sapiens_hsa053323.40501449
5Type I diabetes mellitus_Homo sapiens_hsa049402.82228837
6Antigen processing and presentation_Homo sapiens_hsa046122.72233175
7NF-kappa B signaling pathway_Homo sapiens_hsa040642.69256660
8Cyanoamino acid metabolism_Homo sapiens_hsa004602.19307597
9Hematopoietic cell lineage_Homo sapiens_hsa046402.18591315
10Osteoclast differentiation_Homo sapiens_hsa043802.17009723
11Leishmaniasis_Homo sapiens_hsa051402.14985559
12Protein export_Homo sapiens_hsa030602.07859043
13Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.91000146
14T cell receptor signaling pathway_Homo sapiens_hsa046601.88629906
15Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.74270206
16Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.71537415
17Base excision repair_Homo sapiens_hsa034101.58450482
18Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.55420575
19N-Glycan biosynthesis_Homo sapiens_hsa005101.53264681
20Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.44392661
21Rheumatoid arthritis_Homo sapiens_hsa053231.43605560
22Measles_Homo sapiens_hsa051621.41171909
23Leukocyte transendothelial migration_Homo sapiens_hsa046701.37321200
24RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.32315997
25Chemokine signaling pathway_Homo sapiens_hsa040621.31874316
26Sulfur metabolism_Homo sapiens_hsa009201.30701068
27Toll-like receptor signaling pathway_Homo sapiens_hsa046201.29149221
28Tuberculosis_Homo sapiens_hsa051521.29105182
29Herpes simplex infection_Homo sapiens_hsa051681.28927873
30Fat digestion and absorption_Homo sapiens_hsa049751.25447640
31Renin-angiotensin system_Homo sapiens_hsa046141.24616998
32Asthma_Homo sapiens_hsa053101.23632382
33Arginine biosynthesis_Homo sapiens_hsa002201.23423436
34Ribosome_Homo sapiens_hsa030101.16952716
35Toxoplasmosis_Homo sapiens_hsa051451.15981836
36Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.11182832
37Phagosome_Homo sapiens_hsa041451.10269290
38Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.10195956
39DNA replication_Homo sapiens_hsa030301.09108482
40Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.08885679
41Hepatitis B_Homo sapiens_hsa051611.07095599
42Fructose and mannose metabolism_Homo sapiens_hsa000511.05706708
43NOD-like receptor signaling pathway_Homo sapiens_hsa046211.05562366
44Shigellosis_Homo sapiens_hsa051311.04914315
45Allograft rejection_Homo sapiens_hsa053301.04253140
46Jak-STAT signaling pathway_Homo sapiens_hsa046301.03559251
47Malaria_Homo sapiens_hsa051441.03533238
48Epstein-Barr virus infection_Homo sapiens_hsa051691.02537346
49Non-small cell lung cancer_Homo sapiens_hsa052231.01230533
50Neurotrophin signaling pathway_Homo sapiens_hsa047220.98169555
51Influenza A_Homo sapiens_hsa051640.96695171
52Complement and coagulation cascades_Homo sapiens_hsa046100.96556432
53Platelet activation_Homo sapiens_hsa046110.96110600
54Non-homologous end-joining_Homo sapiens_hsa034500.96091264
55Apoptosis_Homo sapiens_hsa042100.95892204
56Acute myeloid leukemia_Homo sapiens_hsa052210.94384091
57Pertussis_Homo sapiens_hsa051330.93535815
58Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.90002775
59Viral myocarditis_Homo sapiens_hsa054160.88621762
60Systemic lupus erythematosus_Homo sapiens_hsa053220.87595250
61African trypanosomiasis_Homo sapiens_hsa051430.87260355
62Chronic myeloid leukemia_Homo sapiens_hsa052200.87217417
63Autoimmune thyroid disease_Homo sapiens_hsa053200.84059601
64Pancreatic cancer_Homo sapiens_hsa052120.83962818
65HTLV-I infection_Homo sapiens_hsa051660.80949485
66Protein digestion and absorption_Homo sapiens_hsa049740.80701100
67Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.80672744
68Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.77589494
69Mismatch repair_Homo sapiens_hsa034300.77453845
70AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.77215759
71VEGF signaling pathway_Homo sapiens_hsa043700.76368408
72Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.75007318
73Arachidonic acid metabolism_Homo sapiens_hsa005900.74443688
74Mineral absorption_Homo sapiens_hsa049780.74151807
75alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.71611518
76Legionellosis_Homo sapiens_hsa051340.69877912
77TNF signaling pathway_Homo sapiens_hsa046680.69793038
78Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.68026213
79Other glycan degradation_Homo sapiens_hsa005110.66397192
80Viral carcinogenesis_Homo sapiens_hsa052030.65190339
81Hepatitis C_Homo sapiens_hsa051600.64325480
82Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.62974889
83Histidine metabolism_Homo sapiens_hsa003400.62639998
84Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.62209481
85Pancreatic secretion_Homo sapiens_hsa049720.58198037
86Drug metabolism - other enzymes_Homo sapiens_hsa009830.57447726
87Carbohydrate digestion and absorption_Homo sapiens_hsa049730.56206855
88Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.56092937
89Staphylococcus aureus infection_Homo sapiens_hsa051500.55835165
90Vitamin digestion and absorption_Homo sapiens_hsa049770.54502098
91Amoebiasis_Homo sapiens_hsa051460.54051645
92Linoleic acid metabolism_Homo sapiens_hsa005910.52777380
93Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52721171
94Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.51964494
95Prion diseases_Homo sapiens_hsa050200.50635690
96Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.49963592
97Pentose and glucuronate interconversions_Homo sapiens_hsa000400.48254279
98Transcriptional misregulation in cancer_Homo sapiens_hsa052020.48037050
99Small cell lung cancer_Homo sapiens_hsa052220.46582137
100Insulin resistance_Homo sapiens_hsa049310.43202774
101Starch and sucrose metabolism_Homo sapiens_hsa005000.41083431
102Ether lipid metabolism_Homo sapiens_hsa005650.39917744
103Salmonella infection_Homo sapiens_hsa051320.39197307
104Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.38492139
105MAPK signaling pathway_Homo sapiens_hsa040100.37191529
106Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.36613302
107Phosphatidylinositol signaling system_Homo sapiens_hsa040700.35949170
108Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.34967537
109Galactose metabolism_Homo sapiens_hsa000520.34438358
110Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.34157549
111PPAR signaling pathway_Homo sapiens_hsa033200.34060715
112Renal cell carcinoma_Homo sapiens_hsa052110.31715701
113Retinol metabolism_Homo sapiens_hsa008300.31620640
114MicroRNAs in cancer_Homo sapiens_hsa052060.30701292
115Proteoglycans in cancer_Homo sapiens_hsa052050.29687032
116Bladder cancer_Homo sapiens_hsa052190.29164845
117Inositol phosphate metabolism_Homo sapiens_hsa005620.28480172
118Arginine and proline metabolism_Homo sapiens_hsa003300.27846628
119Steroid hormone biosynthesis_Homo sapiens_hsa001400.27818406
120Colorectal cancer_Homo sapiens_hsa052100.27724843
121Glioma_Homo sapiens_hsa052140.27608560
122p53 signaling pathway_Homo sapiens_hsa041150.27555936
123Prolactin signaling pathway_Homo sapiens_hsa049170.27116492
124Caffeine metabolism_Homo sapiens_hsa002320.26786969
125Thyroid hormone synthesis_Homo sapiens_hsa049180.26373166
126Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.25780165
127HIF-1 signaling pathway_Homo sapiens_hsa040660.25760290
128Endocytosis_Homo sapiens_hsa041440.24408828
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.24338378
130FoxO signaling pathway_Homo sapiens_hsa040680.24320819
131Prostate cancer_Homo sapiens_hsa052150.23667675
132Spliceosome_Homo sapiens_hsa030400.22161491
133Long-term potentiation_Homo sapiens_hsa047200.21938994
134Sphingolipid signaling pathway_Homo sapiens_hsa040710.16498689
135Homologous recombination_Homo sapiens_hsa034400.16170592
136Lysosome_Homo sapiens_hsa041420.14071398
137Notch signaling pathway_Homo sapiens_hsa043300.13107588
138Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.13058490
139Adipocytokine signaling pathway_Homo sapiens_hsa049200.12996062
140Aldosterone synthesis and secretion_Homo sapiens_hsa049250.12729845
141mTOR signaling pathway_Homo sapiens_hsa041500.12374670

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