IGLC1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* complement activation (GO:0006956)8.92211419
2antigen processing and presentation of endogenous antigen (GO:0019883)8.75553511
3antigen processing and presentation of endogenous peptide antigen (GO:0002483)7.72384545
4antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)7.72384545
5negative regulation of glucose import (GO:0046325)7.62601087
6B cell receptor signaling pathway (GO:0050853)7.34564714
7cytidine metabolic process (GO:0046087)6.82085582
8cytidine catabolic process (GO:0006216)6.82085582
9cytidine deamination (GO:0009972)6.82085582
10positive regulation of respiratory burst (GO:0060267)6.73107220
11signal peptide processing (GO:0006465)6.53247036
12negative regulation of glucose transport (GO:0010829)6.15054862
13negative regulation of B cell proliferation (GO:0030889)6.14019023
14* immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:00026.03934369
15* Fc-gamma receptor signaling pathway (GO:0038094)6.03934369
16* Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096)6.03934369
17* Fc receptor mediated stimulatory signaling pathway (GO:0002431)5.94981766
18regulation of glucose import in response to insulin stimulus (GO:2001273)5.87170080
19* protein activation cascade (GO:0072376)5.68407792
20somatic hypermutation of immunoglobulin genes (GO:0016446)5.61678366
21somatic diversification of immune receptors via somatic mutation (GO:0002566)5.61678366
22* humoral immune response (GO:0006959)5.58441643
23regulation of B cell receptor signaling pathway (GO:0050855)5.51771795
24pyrimidine ribonucleoside catabolic process (GO:0046133)5.36750350
25regulation of B cell proliferation (GO:0030888)5.33944734
26positive regulation of B cell differentiation (GO:0045579)5.24966435
27Golgi transport vesicle coating (GO:0048200)5.23698492
28T cell migration (GO:0072678)5.23161759
29antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.12825892
30regulation of B cell differentiation (GO:0045577)5.03279268
31glomerular filtration (GO:0003094)4.98057233
32retina homeostasis (GO:0001895)4.97449187
33cellular response to zinc ion (GO:0071294)4.87021031
34negative regulation of bone resorption (GO:0045779)4.65124346
35ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)4.62864232
36regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022354.55296880
37positive regulation of type I interferon-mediated signaling pathway (GO:0060340)4.45042515
38* immune response-activating cell surface receptor signaling pathway (GO:0002429)4.43267669
39renal filtration (GO:0097205)4.42259950
40regulation of respiratory burst (GO:0060263)4.41857460
41myeloid dendritic cell differentiation (GO:0043011)4.36384304
42B cell proliferation (GO:0042100)4.30168981
43positive regulation of immunoglobulin production (GO:0002639)4.27708405
44positive regulation of gamma-delta T cell activation (GO:0046645)4.27632791
45negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)4.23472920
46mature B cell differentiation (GO:0002335)4.22843030
47antimicrobial humoral response (GO:0019730)4.16174045
48antibacterial humoral response (GO:0019731)4.14973932
49hepatocyte apoptotic process (GO:0097284)4.09881530
50keratinization (GO:0031424)4.06406542
51defense response to protozoan (GO:0042832)4.02530329
52maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.95632555
53cellular extravasation (GO:0045123)3.95293226
54mannose metabolic process (GO:0006013)3.93431686
55apoptotic cell clearance (GO:0043277)3.91808882
56dendritic cell chemotaxis (GO:0002407)3.87614793
57protein retention in ER lumen (GO:0006621)3.81088132
58positive regulation of Rap GTPase activity (GO:0032854)3.80737080
59myeloid dendritic cell activation (GO:0001773)3.79605825
60regulation of B cell activation (GO:0050864)3.79181000
61mature B cell differentiation involved in immune response (GO:0002313)3.74554222
62regulation of cellular extravasation (GO:0002691)3.72884654
63regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)3.70133415
64regulation of B cell apoptotic process (GO:0002902)3.67569141
65lymphocyte migration (GO:0072676)3.64652064
66L-fucose catabolic process (GO:0042355)3.62961553
67fucose catabolic process (GO:0019317)3.62961553
68L-fucose metabolic process (GO:0042354)3.62961553
69lymphocyte chemotaxis (GO:0048247)3.62375913
70negative regulation of fibroblast apoptotic process (GO:2000270)3.60694196
71respiratory burst (GO:0045730)3.59766021
72negative regulation of bone remodeling (GO:0046851)3.58349282
73B cell homeostasis (GO:0001782)3.56765948
74positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.48923275
75natural killer cell mediated cytotoxicity (GO:0042267)3.48338419
76natural killer cell mediated immunity (GO:0002228)3.48338419
77endoplasmic reticulum unfolded protein response (GO:0030968)3.46978814
78regulation of fibroblast apoptotic process (GO:2000269)3.46742751
79activation of signaling protein activity involved in unfolded protein response (GO:0006987)3.46735583
80positive regulation of nuclease activity (GO:0032075)3.44234492
81response to interferon-alpha (GO:0035455)3.43467033
82regulation of nuclease activity (GO:0032069)3.42018213
83protein N-linked glycosylation via asparagine (GO:0018279)3.39199172
84leukocyte tethering or rolling (GO:0050901)3.39010128
85regulation of type I interferon-mediated signaling pathway (GO:0060338)3.38860366
86antigen receptor-mediated signaling pathway (GO:0050851)3.38759971
87regulation of interferon-beta biosynthetic process (GO:0045357)3.36741501
88positive regulation of Rho protein signal transduction (GO:0035025)3.35796189
89peptidyl-asparagine modification (GO:0018196)3.35306627
90cellular response to unfolded protein (GO:0034620)3.31920470
91multicellular organismal water homeostasis (GO:0050891)3.31121781
92regulation of dendritic cell antigen processing and presentation (GO:0002604)3.30430606
93GDP-mannose metabolic process (GO:0019673)3.27815372
94regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.27799719
95B cell activation (GO:0042113)3.26822512
96response to protozoan (GO:0001562)3.25936952
97regulation of gamma-delta T cell differentiation (GO:0045586)3.25118227
98regulation of immunoglobulin production (GO:0002637)3.23694447
99regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)3.23513864
100exocrine pancreas development (GO:0031017)3.23504420
101detection of bacterium (GO:0016045)3.23208371
102cellular response to type I interferon (GO:0071357)3.22847929
103type I interferon signaling pathway (GO:0060337)3.22847929
104negative regulation of cellular response to insulin stimulus (GO:1900077)3.22739734
105response to type I interferon (GO:0034340)3.21740010
106negative regulation of B cell activation (GO:0050869)3.19843458
107interleukin-6-mediated signaling pathway (GO:0070102)3.19636776
108germinal center formation (GO:0002467)3.19543155
109dendritic cell differentiation (GO:0097028)3.19132983
110cellular response to antibiotic (GO:0071236)3.18104214
111response to endoplasmic reticulum stress (GO:0034976)3.17891171
112response to hydroperoxide (GO:0033194)3.17816668
113* immune response-activating signal transduction (GO:0002757)3.16303049
114regulation of Rap GTPase activity (GO:0032317)3.15356963
115cellular response to virus (GO:0098586)3.13098023
116mitochondrion distribution (GO:0048311)3.11804462
117protein N-linked glycosylation (GO:0006487)3.11320833
118regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.11292930
119regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.10323986
120cellular response to topologically incorrect protein (GO:0035967)3.09037335
121somatic diversification of immunoglobulins (GO:0016445)3.08659957
122negative regulation of B cell apoptotic process (GO:0002903)3.07437327
123negative regulation of gene silencing (GO:0060969)3.06347501
124detection of other organism (GO:0098543)3.05978506
125negative regulation of tissue remodeling (GO:0034104)3.05358692
126positive regulation of B cell proliferation (GO:0030890)3.05161796
127positive regulation of antigen processing and presentation (GO:0002579)3.04133576
128ER-nucleus signaling pathway (GO:0006984)3.02833104
129regulation of interleukin-12 biosynthetic process (GO:0045075)3.00961655
130positive regulation of B cell activation (GO:0050871)3.00763537
131B cell activation involved in immune response (GO:0002312)3.00733502
132positive regulation of protein homooligomerization (GO:0032464)3.00692566
133angiotensin maturation (GO:0002003)3.00329839
134regulation of necroptotic process (GO:0060544)2.97205766
135mitochondrial calcium ion transport (GO:0006851)2.94707650
136negative thymic T cell selection (GO:0045060)2.93594997
137cell redox homeostasis (GO:0045454)2.92415797
138positive regulation of gene expression, epigenetic (GO:0045815)2.90248598
139L-serine transport (GO:0015825)2.90199060
140regulation of antigen processing and presentation (GO:0002577)2.89053836
141regulation of gamma-delta T cell activation (GO:0046643)2.89024487
142lymphocyte homeostasis (GO:0002260)2.88812792
143negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.88554319
144defense response to Gram-negative bacterium (GO:0050829)2.88548625
145SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.88377860
146negative regulation of necroptotic process (GO:0060546)2.88359045
147modulation by virus of host process (GO:0019054)2.88213156
148UDP-N-acetylglucosamine metabolic process (GO:0006047)2.88016710
149positive regulation of Cdc42 GTPase activity (GO:0043089)2.87584884
150post-embryonic morphogenesis (GO:0009886)2.87466217
151regulation of necrotic cell death (GO:0010939)2.87356890
152N-acetylneuraminate metabolic process (GO:0006054)2.85947464
153* activation of immune response (GO:0002253)2.84770797
154dendritic cell migration (GO:0036336)2.83882095
155COPI coating of Golgi vesicle (GO:0048205)2.83729507
156keratinocyte differentiation (GO:0030216)2.82392025
157regulation of water loss via skin (GO:0033561)2.80413505
158amyloid precursor protein metabolic process (GO:0042982)2.80353200
159positive regulation of T cell migration (GO:2000406)2.78640888
160modulation by symbiont of host cellular process (GO:0044068)2.78300403
161positive regulation of lymphocyte migration (GO:2000403)2.77606321
162retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.77149205
163adhesion of symbiont to host cell (GO:0044650)2.76908092
164* complement activation, classical pathway (GO:0006958)11.7515342

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.12257967
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.41179246
3IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.85352967
4MYC_22102868_ChIP-Seq_BL_Human4.41703313
5E2F7_22180533_ChIP-Seq_HELA_Human3.99841362
6SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.99459521
7IRF8_21731497_ChIP-ChIP_J774_Mouse3.98439301
8FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.90414151
9E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human3.38561668
10STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.20222964
11CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.95069476
12VDR_21846776_ChIP-Seq_THP-1_Human2.86564132
13MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.78299610
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.69560183
15IRF8_27001747_Chip-Seq_BMDM_Mouse2.67260467
16TP63_17297297_ChIP-ChIP_HaCaT_Human2.60271559
17MAF_26560356_Chip-Seq_TH1_Human2.49012052
18RUNX_20019798_ChIP-Seq_JUKART_Human2.48855995
19BP1_19119308_ChIP-ChIP_Hs578T_Human2.48550896
20MYB_26560356_Chip-Seq_TH2_Human2.33235077
21MYB_26560356_Chip-Seq_TH1_Human2.30851313
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.23457722
23SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.15993305
24FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.15817490
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.15158941
26NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.03073341
27STAT4_19710469_ChIP-ChIP_TH1__Mouse2.01768887
28EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.97664912
29IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.92954510
30UTX_26944678_Chip-Seq_JUKART_Human1.90500282
31SPI1_23547873_ChIP-Seq_NB4_Human1.89361405
32STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.85007096
33VDR_24763502_ChIP-Seq_THP-1_Human1.84742135
34NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.81479388
35CLOCK_20551151_ChIP-Seq_293T_Human1.78602156
36ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.76886874
37SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.75771408
38BRD4_27068464_Chip-Seq_AML-cells_Mouse1.72129671
39KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.68361844
40ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.67126416
41CIITA_25753668_ChIP-Seq_RAJI_Human1.66182609
42RACK7_27058665_Chip-Seq_MCF-7_Human1.61833949
43KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.61639942
44STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.60584282
45PU.1_20513432_ChIP-Seq_Bcells_Mouse1.59960424
46SOX2_27498859_Chip-Seq_STOMACH_Mouse1.58252900
47FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.57469746
48RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.57065127
49TCF7_22412390_ChIP-Seq_EML_Mouse1.55830299
50SCL_19346495_ChIP-Seq_HPC-7_Human1.54841032
51ELF1_17652178_ChIP-ChIP_JURKAT_Human1.54422408
52GATA2_22383799_ChIP-Seq_G1ME_Mouse1.47471891
53GATA3_27048872_Chip-Seq_THYMUS_Human1.47234542
54MAF_26560356_Chip-Seq_TH2_Human1.47133087
55RUNX1_22412390_ChIP-Seq_EML_Mouse1.45739086
56FOXM1_23109430_ChIP-Seq_U2OS_Human1.45634299
57NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.40819929
58GATA1_22383799_ChIP-Seq_G1ME_Mouse1.37493578
59TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.36824544
60VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.36248439
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.35462082
62KDM5A_27292631_Chip-Seq_BREAST_Human1.32284418
63DNAJC2_21179169_ChIP-ChIP_NT2_Human1.30529574
64MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.27400610
65KDM2B_26808549_Chip-Seq_DND41_Human1.27050945
66FOXO3_23340844_ChIP-Seq_DLD1_Human1.25624304
67MYB_21317192_ChIP-Seq_ERMYB_Mouse1.24081622
68RXR_22158963_ChIP-Seq_LIVER_Mouse1.24012319
69KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.23501144
70KDM2B_26808549_Chip-Seq_SUP-B15_Human1.23400649
71SPI1_23127762_ChIP-Seq_K562_Human1.22872854
72GATA6_25053715_ChIP-Seq_YYC3_Human1.21278313
73TFEB_21752829_ChIP-Seq_HELA_Human1.21255371
74TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.20866737
75TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.20573594
76RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.20499561
77FOXP3_21729870_ChIP-Seq_TREG_Human1.19003801
78VDR_23849224_ChIP-Seq_CD4+_Human1.18719132
79ERG_20887958_ChIP-Seq_HPC-7_Mouse1.18546272
80PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.16665430
81GATA3_26560356_Chip-Seq_TH2_Human1.15827210
82P63_26484246_Chip-Seq_KERATINOCYTES_Human1.11406743
83SMC4_20622854_ChIP-Seq_HELA_Human1.10893654
84PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.10404827
85E2F4_17652178_ChIP-ChIP_JURKAT_Human1.07689997
86MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.06830252
87ETS1_21867929_ChIP-Seq_TH2_Mouse1.06540548
88GATA1_19941826_ChIP-Seq_K562_Human1.06143588
89KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.06099000
90SA1_27219007_Chip-Seq_ERYTHROID_Human1.05927357
91GATA1_22025678_ChIP-Seq_K562_Human1.05446169
92SA1_27219007_Chip-Seq_Bcells_Human1.04860317
93NOTCH1_21737748_ChIP-Seq_TLL_Human1.04461682
94CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.04140226
95ELK3_25401928_ChIP-Seq_HUVEC_Human1.03718957
96CTCF_27219007_Chip-Seq_ERYTHROID_Human1.03317752
97HOXB4_20404135_ChIP-ChIP_EML_Mouse1.02404843
98GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.99823027
99CHD1_26751641_Chip-Seq_LNCaP_Human0.99266443
100GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.96918298
101CTCF_21964334_ChIP-Seq_BJAB-B_Human0.96122606
102RARG_19884340_ChIP-ChIP_MEFs_Mouse0.96046421
103TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.94956085
104P300_27058665_Chip-Seq_ZR-75-30cells_Human0.94945405
105RUNX1_27514584_Chip-Seq_MCF-7_Human0.94062918
106LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.93850318
107SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.93776770
108LXR_22292898_ChIP-Seq_THP-1_Human0.93238108
109CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.92863872
110P300_27268052_Chip-Seq_Bcells_Human0.90898114
111ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.90667565
112GABP_17652178_ChIP-ChIP_JURKAT_Human0.88757371
113CREB1_15753290_ChIP-ChIP_HEK293T_Human0.88739513
114CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.88585569
115PPARA_22158963_ChIP-Seq_LIVER_Mouse0.87254689
116MYC_19079543_ChIP-ChIP_MESCs_Mouse0.86487023
117PU_27001747_Chip-Seq_BMDM_Mouse0.85867360
118CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.85513163
119BCL6_27268052_Chip-Seq_Bcells_Human0.85212743
120CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.85070370
121EST1_17652178_ChIP-ChIP_JURKAT_Human0.84778934
122ETS1_20019798_ChIP-Seq_JURKAT_Human0.83844081
123KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.83013795
124SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.82576358
125GATA3_26560356_Chip-Seq_TH1_Human0.82355530
126NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.82206978
127PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.81442955
128THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.81402247
129STAT1_20625510_ChIP-Seq_HELA_Human0.79838480
130CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.79760491
131ELF1_20517297_ChIP-Seq_JURKAT_Human0.79348038
132NCOR1_26117541_ChIP-Seq_K562_Human0.77742990
133CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.75924648
134FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75551020

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation6.35703701
2MP0001800_abnormal_humoral_immune5.02482408
3MP0003303_peritoneal_inflammation4.44394437
4MP0001790_abnormal_immune_system4.39386549
5MP0005387_immune_system_phenotype4.39386549
6MP0002452_abnormal_antigen_presenting3.78644570
7MP0005671_abnormal_response_to3.59436199
8MP0000685_abnormal_immune_system3.18087913
9MP0002723_abnormal_immune_serum3.14759484
10MP0002420_abnormal_adaptive_immunity3.05481521
11MP0001819_abnormal_immune_cell2.98696469
12MP0005000_abnormal_immune_tolerance2.95518397
13* MP0002398_abnormal_bone_marrow2.72337544
14MP0010234_abnormal_vibrissa_follicle2.68150848
15* MP0000716_abnormal_immune_system2.60619564
16MP0004264_abnormal_extraembryonic_tissu2.57829877
17MP0000689_abnormal_spleen_morphology2.57444192
18MP0001879_abnormal_lymphatic_vessel2.49280285
19MP0005025_abnormal_response_to2.38350841
20MP0002796_impaired_skin_barrier2.35300173
21MP0003300_gastrointestinal_ulcer2.29930485
22MP0003724_increased_susceptibility_to2.29397465
23MP0002166_altered_tumor_susceptibility2.23544608
24MP0002148_abnormal_hypersensitivity_rea2.23175139
25* MP0002429_abnormal_blood_cell2.17752364
26MP0003763_abnormal_thymus_physiology2.09304008
27MP0002722_abnormal_immune_system2.09293947
28MP0004043_abnormal_pH_regulation1.96906111
29MP0003436_decreased_susceptibility_to1.91481802
30MP0004782_abnormal_surfactant_physiolog1.88568222
31MP0009785_altered_susceptibility_to1.87762391
32MP0006054_spinal_hemorrhage1.87277056
33MP0002419_abnormal_innate_immunity1.83305774
34MP0001845_abnormal_inflammatory_respons1.81456094
35MP0009840_abnormal_foam_cell1.80467431
36MP0010155_abnormal_intestine_physiology1.80270112
37MP0002138_abnormal_hepatobiliary_system1.69311485
38MP0002933_joint_inflammation1.65095468
39MP0002006_tumorigenesis1.64489155
40MP0003693_abnormal_embryo_hatching1.61884477
41MP0005275_abnormal_skin_tensile1.59882765
42MP0004947_skin_inflammation1.58877509
43MP0010307_abnormal_tumor_latency1.55891794
44MP0005310_abnormal_salivary_gland1.54372308
45MP0005451_abnormal_body_composition1.52921815
46MP0009333_abnormal_splenocyte_physiolog1.50049129
47MP0002405_respiratory_system_inflammati1.44072910
48MP0000703_abnormal_thymus_morphology1.41660492
49MP0004510_myositis1.40073375
50MP0001853_heart_inflammation1.37855685
51MP0001873_stomach_inflammation1.35344928
52MP0003866_abnormal_defecation1.33876640
53MP0004858_abnormal_nervous_system1.33178630
54MP0003453_abnormal_keratinocyte_physiol1.32270343
55MP0002019_abnormal_tumor_incidence1.28544147
56MP0002876_abnormal_thyroid_physiology1.26455074
57MP0005503_abnormal_tendon_morphology1.24422456
58MP0005166_decreased_susceptibility_to1.20621107
59MP0000490_abnormal_crypts_of1.18365960
60MP0002139_abnormal_hepatobiliary_system1.16032972
61MP0005501_abnormal_skin_physiology1.14962367
62MP0001270_distended_abdomen1.12308340
63MP0008004_abnormal_stomach_pH1.10022668
64MP0005220_abnormal_exocrine_pancreas1.09582079
65MP0002396_abnormal_hematopoietic_system1.07597821
66MP0003195_calcinosis1.05459282
67MP0002136_abnormal_kidney_physiology1.04568036
68MP0005464_abnormal_platelet_physiology1.02855418
69MP0000003_abnormal_adipose_tissue1.00955739
70MP0000465_gastrointestinal_hemorrhage1.00845710
71MP0003868_abnormal_feces_composition1.00444184
72MP0006082_CNS_inflammation1.00255562
73MP0003191_abnormal_cellular_cholesterol0.98958452
74MP0003252_abnormal_bile_duct0.97435677
75MP0001765_abnormal_ion_homeostasis0.96626831
76MP0004808_abnormal_hematopoietic_stem0.94470205
77MP0001191_abnormal_skin_condition0.94374602
78MP0001216_abnormal_epidermal_layer0.94371762
79MP0003183_abnormal_peptide_metabolism0.94040448
80MP0008260_abnormal_autophagy0.91081724
81MP0008438_abnormal_cutaneous_collagen0.90405154
82MP0010094_abnormal_chromosome_stability0.90033717
83MP0005360_urolithiasis0.88933591
84MP0002693_abnormal_pancreas_physiology0.87047959
85MP0002098_abnormal_vibrissa_morphology0.86787378
86MP0001851_eye_inflammation0.86008897
87MP0000013_abnormal_adipose_tissue0.85534872
88MP0008469_abnormal_protein_level0.84378643
89MP0001663_abnormal_digestive_system0.83003263
90MP0005390_skeleton_phenotype0.81125725
91MP0005409_darkened_coat_color0.79742409
92MP0005076_abnormal_cell_differentiation0.79157187
93MP0005584_abnormal_enzyme/coenzyme_acti0.77816826
94MP0004084_abnormal_cardiac_muscle0.74293836
95MP0008057_abnormal_DNA_replication0.73200800
96MP0001944_abnormal_pancreas_morphology0.71433413
97MP0003656_abnormal_erythrocyte_physiolo0.71092461
98MP0003077_abnormal_cell_cycle0.70912058
99MP0001533_abnormal_skeleton_physiology0.70391148
100MP0010352_gastrointestinal_tract_polyps0.69200926
101MP0001919_abnormal_reproductive_system0.67068005
102MP0002083_premature_death0.66658099
103MP0000377_abnormal_hair_follicle0.65786698
104MP0003638_abnormal_response/metabolism_0.65576531
105MP0000609_abnormal_liver_physiology0.65217921
106MP0000477_abnormal_intestine_morphology0.64779281
107MP0002060_abnormal_skin_morphology0.64304048
108MP0002168_other_aberrant_phenotype0.64060236
109MP0003045_fibrosis0.62428241
110MP0005058_abnormal_lysosome_morphology0.62300526
111MP0001664_abnormal_digestion0.62287263
112MP0003075_altered_response_to0.61665509
113MP0000604_amyloidosis0.61545915
114MP0003943_abnormal_hepatobiliary_system0.57480168
115MP0009931_abnormal_skin_appearance0.56536019
116MP0009643_abnormal_urine_homeostasis0.55368750
117MP0004957_abnormal_blastocyst_morpholog0.54922656
118MP0005023_abnormal_wound_healing0.51681829
119MP0001666_abnormal_nutrient_absorption0.51604089
120MP0000313_abnormal_cell_death0.51156599
121MP0002998_abnormal_bone_remodeling0.50590575
122MP0005397_hematopoietic_system_phenotyp0.49438749
123MP0001545_abnormal_hematopoietic_system0.49438749
124MP0000858_altered_metastatic_potential0.48262550
125MP0000350_abnormal_cell_proliferation0.47742604
126MP0005621_abnormal_cell_physiology0.45936374
127MP0009763_increased_sensitivity_to0.43772082
128MP0009764_decreased_sensitivity_to0.42529895
129MP0005381_digestive/alimentary_phenotyp0.42505782
130MP0000681_abnormal_thyroid_gland0.42290033
131MP0005388_respiratory_system_phenotype0.42026335
132MP0002133_abnormal_respiratory_system0.42026335
133MP0003795_abnormal_bone_structure0.39980431
134MP0001730_embryonic_growth_arrest0.39335809
135MP0003091_abnormal_cell_migration0.37872117
136MP0008873_increased_physiological_sensi0.37761328
137MP0009765_abnormal_xenobiotic_induced0.36940838
138MP0000598_abnormal_liver_morphology0.36708861

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of B cell number (HP:0010975)8.10512202
2B lymphocytopenia (HP:0010976)8.10512202
3Colitis (HP:0002583)7.64429881
4Recurrent sinusitis (HP:0011108)7.59547888
5Recurrent bronchitis (HP:0002837)7.46132306
6Cellulitis (HP:0100658)7.07155652
7Gastrointestinal stroma tumor (HP:0100723)6.58139507
8Verrucae (HP:0200043)6.41029431
9Papilloma (HP:0012740)6.41029431
10Hyperactive renin-angiotensin system (HP:0000841)5.90372505
11Inflammation of the large intestine (HP:0002037)5.87701344
12IgM deficiency (HP:0002850)5.68826185
13Recurrent viral infections (HP:0004429)5.63289439
14Gastrointestinal inflammation (HP:0004386)5.61156214
15Recurrent pneumonia (HP:0006532)5.50985026
16Decreased circulating renin level (HP:0003351)5.47906278
17Chronic sinusitis (HP:0011109)5.15058905
18Meningitis (HP:0001287)5.12475069
19Recurrent lower respiratory tract infections (HP:0002783)4.90693612
20Chronic otitis media (HP:0000389)4.64945716
21Malnutrition (HP:0004395)4.61742010
22Osteomyelitis (HP:0002754)4.44514600
23Systemic lupus erythematosus (HP:0002725)4.39327435
24Bronchitis (HP:0012387)4.38316312
25Emphysema (HP:0002097)4.25502994
26Recurrent otitis media (HP:0000403)4.10849174
27IgA deficiency (HP:0002720)4.06413257
28Lymphopenia (HP:0001888)3.75326315
29Sepsis (HP:0100806)3.61367553
30Abnormality of cells of the lymphoid lineage (HP:0012140)3.61247701
31IgG deficiency (HP:0004315)3.59492271
32Abnormality of small intestinal villus morphology (HP:0011472)3.59361062
33Villous atrophy (HP:0011473)3.59361062
34Skin rash (HP:0000988)3.55142903
35Nuclear cataract (HP:0100018)3.44024773
36Vasculitis (HP:0002633)3.37666345
37Interstitial pulmonary disease (HP:0006530)3.35651176
38Abnormality of T cell physiology (HP:0011840)3.21348512
39Restrictive lung disease (HP:0002091)3.16585658
40Hyperkalemia (HP:0002153)3.16310735
41Thyroiditis (HP:0100646)3.12739940
42Abnormality of renin-angiotensin system (HP:0000847)3.10752644
43Elevated erythrocyte sedimentation rate (HP:0003565)3.02133166
44Abnormal delayed hypersensitivity skin test (HP:0002963)3.01391677
45Abnormality of nail color (HP:0100643)2.98780989
46Panhypogammaglobulinemia (HP:0003139)2.97726180
47Hypokalemic alkalosis (HP:0001949)2.90495975
48Autoimmune hemolytic anemia (HP:0001890)2.88683813
49Recurrent abscess formation (HP:0002722)2.86185694
50Nephritis (HP:0000123)2.82007534
51Nasal polyposis (HP:0100582)2.80950527
52Spontaneous hematomas (HP:0007420)2.72239272
53Glomerulonephritis (HP:0000099)2.69162951
54Hyperaldosteronism (HP:0000859)2.68808995
55Plantar hyperkeratosis (HP:0007556)2.68526410
56Alkalosis (HP:0001948)2.68393129
57Recurrent fungal infections (HP:0002841)2.67427212
58Cone-rod dystrophy (HP:0000548)2.65205322
59Palmoplantar hyperkeratosis (HP:0000972)2.63011312
60Small epiphyses (HP:0010585)2.62843461
61Basal cell carcinoma (HP:0002671)2.62323699
62Zonular cataract (HP:0010920)2.61561003
63Abnormality of T cells (HP:0002843)2.59736999
64Recurrent bacterial skin infections (HP:0005406)2.58757797
65Chronic bronchitis (HP:0004469)2.58311270
66Abnormality of complement system (HP:0005339)2.57198984
67Neutropenia (HP:0001875)2.54680967
68Abnormality of glycosphingolipid metabolism (HP:0004343)2.48730666
69Abnormality of glycolipid metabolism (HP:0010969)2.48730666
70Abnormality of liposaccharide metabolism (HP:0010968)2.48730666
71Erythema (HP:0010783)2.48035528
72Bronchiectasis (HP:0002110)2.47547719
73Onycholysis (HP:0001806)2.45674736
74Alopecia of scalp (HP:0002293)2.44576888
75Hyponatremia (HP:0002902)2.43196749
76Renal salt wasting (HP:0000127)2.42937619
77Palmar hyperkeratosis (HP:0010765)2.41415472
78Leukopenia (HP:0001882)2.40025148
79Abnormality of chloride homeostasis (HP:0011422)2.39234088
80Complement deficiency (HP:0004431)2.37983709
81Dysostosis multiplex (HP:0000943)2.35132241
82Skin ulcer (HP:0200042)2.33417505
83Abnormality of the nasal mucosa (HP:0000433)2.33148636
84Adrenal overactivity (HP:0002717)2.31549497
85Ankyloglossia (HP:0010296)2.30375669
86Eczematoid dermatitis (HP:0000976)2.29216683
87Lower limb hyperreflexia (HP:0002395)2.28941224
88Hyperparathyroidism (HP:0000843)2.27899703
89Mediastinal lymphadenopathy (HP:0100721)2.25444000
90Recurrent skin infections (HP:0001581)2.23786487
91Thick nail (HP:0001805)2.23468874
92Right ventricular cardiomyopathy (HP:0011663)2.20638028
93Thrombocytosis (HP:0001894)2.20082306
94Urticaria (HP:0001025)2.19855076
95Myositis (HP:0100614)2.18514571
96Lymphoma (HP:0002665)2.18366053
97Increased IgE level (HP:0003212)2.17865030
98Congenital ichthyosiform erythroderma (HP:0007431)2.15414063
99Abnormality of glutamine family amino acid metabolism (HP:0010902)2.12439663
100Pustule (HP:0200039)2.11087270
101Squamous cell carcinoma (HP:0002860)2.09580905
102Abnormal tarsal ossification (HP:0008369)2.08368812
103Chronic mucocutaneous candidiasis (HP:0002728)2.07304402
104Recurrent cutaneous fungal infections (HP:0011370)2.07304402
105Mitral stenosis (HP:0001718)2.07191881
106Autoimmune thrombocytopenia (HP:0001973)2.04745570
107Esophageal neoplasm (HP:0100751)2.04065639
108Neoplasm of head and neck (HP:0012288)2.04065639
109Dehydration (HP:0001944)2.01707229
110Parakeratosis (HP:0001036)2.00235594
111Agammaglobulinemia (HP:0004432)10.5038689
112Dry hair (HP:0011359)1.97515956
113Hypercortisolism (HP:0001578)1.94289999
114Recurrent gram-negative bacterial infections (HP:0005420)1.92825677
115Abnormality of T cell number (HP:0011839)1.92773786
116Hypotension (HP:0002615)1.91324225
117Xerostomia (HP:0000217)1.91159562
118Gingivitis (HP:0000230)1.90114322
119Viral hepatitis (HP:0006562)1.89783192
120Obstructive lung disease (HP:0006536)1.89536512
121Chronic obstructive pulmonary disease (HP:0006510)1.89536512
122Abnormality of macrophages (HP:0004311)1.88770156
123Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.87748430
124Pulmonary infiltrates (HP:0002113)1.87555132
125Nonimmune hydrops fetalis (HP:0001790)1.87241387
126Hypergammaglobulinemia (HP:0010702)1.85845946
127Rhabdomyolysis (HP:0003201)1.85629757
128Exocrine pancreatic insufficiency (HP:0001738)1.84627463
129Prostate neoplasm (HP:0100787)1.83463163
130Loss of speech (HP:0002371)1.82109847
131Vertebral compression fractures (HP:0002953)1.81273571
132T lymphocytopenia (HP:0005403)1.81250525
133Encephalitis (HP:0002383)1.79650456
134Arthralgia (HP:0002829)1.78632980
135Flattened epiphyses (HP:0003071)1.78059304
136Teleangiectasia of the skin (HP:0100585)1.69379718
137Abnormality of the fingertips (HP:0001211)1.67737479
138Conical tooth (HP:0000698)1.64558570
139Vacuolated lymphocytes (HP:0001922)1.63468562
140Combined immunodeficiency (HP:0005387)1.58827647
141Microcytic anemia (HP:0001935)1.55372975
142Premature loss of primary teeth (HP:0006323)1.55296437
143External ear malformation (HP:0008572)1.54663896
144Hypoplasia of the capital femoral epiphysis (HP:0003090)1.50969774
145Myocardial infarction (HP:0001658)1.50025995
146Petechiae (HP:0000967)1.50021725
147Severe combined immunodeficiency (HP:0004430)1.44861379
148Chronic diarrhea (HP:0002028)1.43419199
149Irregular vertebral endplates (HP:0003301)1.40076355
150Ridged nail (HP:0001807)1.38388524
151Blepharitis (HP:0000498)1.35144514
152Eosinophilia (HP:0001880)1.33265037
153Seborrheic dermatitis (HP:0001051)1.32140647
154Macroorchidism (HP:0000053)1.30281482
155Abnormality of incisor morphology (HP:0011063)1.26848481
156Fatigue (HP:0012378)1.24971644

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN16.99074366
2MAP4K15.88330743
3PRPF4B4.28680441
4NME23.81465376
5GRK63.03827261
6CSF1R2.89993896
7MAP3K102.89479138
8SYK2.86524907
9BLK2.73260657
10TBK12.47295223
11RIPK42.40689501
12MAP3K142.40427754
13TYK22.26600894
14MAP3K132.13145108
15KIT1.99676002
16EIF2AK31.98870634
17TAOK31.96206853
18BTK1.92011913
19LYN1.71931368
20IKBKE1.68954961
21IRAK31.51993364
22PRKCH1.50405539
23RIPK11.48634044
24STK241.45024953
25MST1R1.35251246
26IRAK41.34107014
27MARK21.30547584
28PKN21.27542596
29SIK21.25721082
30LRRK21.23211363
31IKBKB1.18903710
32NEK21.18887428
33EPHA21.18176120
34HCK1.14608074
35PRKCQ1.13210593
36STK101.09511893
37MST41.08716373
38MAP3K91.07893144
39JAK11.07131557
40ITK1.05231289
41MET1.04988564
42TEC1.04828773
43JAK31.02248087
44PRKCI0.98236418
45DYRK1B0.94709014
46MATK0.94298630
47ARAF0.93767776
48LCK0.92907235
49MAP3K10.90925268
50NEK90.90630143
51FES0.87430143
52CSK0.84540189
53HIPK20.84150788
54EIF2AK10.81346521
55BCKDK0.81237767
56PIM10.80883887
57RPS6KA40.78304782
58SMG10.78144255
59PAK40.78114275
60PTK20.75889861
61CLK10.74491172
62FRK0.71601461
63CDC42BPA0.70302666
64CCNB10.68240377
65YES10.66755562
66FGFR30.65382704
67EEF2K0.64763001
68ZAP700.64412107
69TGFBR20.59447188
70EPHA30.55164898
71BRD40.54013864
72TESK20.52721037
73CHUK0.52563388
74PDK10.52184340
75GRK10.52105449
76PIK3CG0.50530291
77TXK0.49176579
78FGFR40.49147676
79ACVR1B0.48816848
80MAPK70.48608117
81CDK60.46405800
82FYN0.45950097
83TRIB30.45544978
84PRKCD0.44424437
85CDK190.43986298
86BMX0.42388538
87MAP2K20.41790193
88ALK0.41614491
89SIK10.41402790
90TAOK10.41215962
91SIK30.41202722
92MAPK110.39422577
93JAK20.39390192
94CDK40.39245834
95BUB10.39071083
96MAPK120.39068520
97INSR0.38547862
98SCYL20.38543428
99KSR20.38463045
100MAP3K110.38214440
101PDPK10.37623341
102PIM20.36463567
103ABL10.35974537
104SGK30.35763525
105MAPK30.35058142
106BRAF0.34323055
107CDK30.34303619
108RPS6KL10.33489248
109RPS6KC10.33489248
110MARK30.33485455
111MAP2K60.33357318
112RAF10.32541890
113PRKD10.32216272
114MAP2K30.31496980
115CDC70.30783397
116MAP3K80.30323996
117IRAK10.28569314
118LMTK20.27920323
119PRKD20.27849975
120PRKAA20.27520057
121CDK90.26721589
122CHEK20.26354373
123STK40.26286502
124MAP3K30.26238041
125MAP3K70.26174522
126EGFR0.26040603
127MAPK40.25874837
128TNK20.25742957
129PIK3CA0.25446487
130SGK20.25155855
131PKN10.24503846
132TLK10.22309768
133EPHB10.20587656
134CSNK1A1L0.19855763
135FLT30.19826518
136MAPKAPK20.19255003
137CDK120.18713827
138MELK0.17558862
139RPS6KB20.16988309
140FGR0.16552428

Predicted pathways (KEGG)

RankGene SetZ-score
1Intestinal immune network for IgA production_Homo sapiens_hsa046726.84082739
2Primary immunodeficiency_Homo sapiens_hsa053406.34871798
3B cell receptor signaling pathway_Homo sapiens_hsa046624.91913354
4Protein export_Homo sapiens_hsa030604.39889432
5Protein processing in endoplasmic reticulum_Homo sapiens_hsa041413.31304861
6Cyanoamino acid metabolism_Homo sapiens_hsa004603.25473730
7N-Glycan biosynthesis_Homo sapiens_hsa005102.56460731
8Antigen processing and presentation_Homo sapiens_hsa046122.49648689
9NF-kappa B signaling pathway_Homo sapiens_hsa040642.29235700
10Base excision repair_Homo sapiens_hsa034102.12758402
11Type I diabetes mellitus_Homo sapiens_hsa049401.77162034
12Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.71188281
13DNA replication_Homo sapiens_hsa030301.64117080
14Osteoclast differentiation_Homo sapiens_hsa043801.64100935
15Asthma_Homo sapiens_hsa053101.62994500
16Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.59894170
17Sulfur metabolism_Homo sapiens_hsa009201.57975107
18Leishmaniasis_Homo sapiens_hsa051401.56029636
19Hematopoietic cell lineage_Homo sapiens_hsa046401.49488521
20Non-homologous end-joining_Homo sapiens_hsa034501.43391151
21Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.41408967
22Renin-angiotensin system_Homo sapiens_hsa046141.37585591
23Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.35081378
24T cell receptor signaling pathway_Homo sapiens_hsa046601.32749006
25Arginine biosynthesis_Homo sapiens_hsa002201.31144641
26Mismatch repair_Homo sapiens_hsa034301.23509202
27RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.14323751
28Ribosome_Homo sapiens_hsa030101.10136861
29Measles_Homo sapiens_hsa051621.08378386
30Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.05722719
31Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.04306020
32Other glycan degradation_Homo sapiens_hsa005111.02208871
33Allograft rejection_Homo sapiens_hsa053301.01519064
34Leukocyte transendothelial migration_Homo sapiens_hsa046701.00855004
35Herpes simplex infection_Homo sapiens_hsa051681.00555110
36Tuberculosis_Homo sapiens_hsa051521.00187808
37Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.00041580
38Fat digestion and absorption_Homo sapiens_hsa049750.99183630
39Toll-like receptor signaling pathway_Homo sapiens_hsa046200.95975392
40Fructose and mannose metabolism_Homo sapiens_hsa000510.95197879
41Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.89388858
42Chemokine signaling pathway_Homo sapiens_hsa040620.89318753
43Hepatitis B_Homo sapiens_hsa051610.88418197
44Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.87375334
45Viral myocarditis_Homo sapiens_hsa054160.83199722
46Malaria_Homo sapiens_hsa051440.82516480
47Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.82487843
48Rheumatoid arthritis_Homo sapiens_hsa053230.81808018
49Glycosaminoglycan degradation_Homo sapiens_hsa005310.79713185
50Apoptosis_Homo sapiens_hsa042100.79465008
51Epstein-Barr virus infection_Homo sapiens_hsa051690.77612761
52Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.76561297
53Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.76054679
54alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.75832789
55Non-small cell lung cancer_Homo sapiens_hsa052230.75120197
56HTLV-I infection_Homo sapiens_hsa051660.71960266
57Legionellosis_Homo sapiens_hsa051340.71411568
58NOD-like receptor signaling pathway_Homo sapiens_hsa046210.70151115
59Arachidonic acid metabolism_Homo sapiens_hsa005900.70053574
60Neurotrophin signaling pathway_Homo sapiens_hsa047220.69218793
61Influenza A_Homo sapiens_hsa051640.68792855
62Pancreatic secretion_Homo sapiens_hsa049720.68630410
63Shigellosis_Homo sapiens_hsa051310.68610604
64Pertussis_Homo sapiens_hsa051330.68104350
65Toxoplasmosis_Homo sapiens_hsa051450.66774668
66Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.66233967
67Jak-STAT signaling pathway_Homo sapiens_hsa046300.64410927
68Autoimmune thyroid disease_Homo sapiens_hsa053200.64282860
69Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.63481879
70Prion diseases_Homo sapiens_hsa050200.63330968
71Proteasome_Homo sapiens_hsa030500.61884593
72Carbohydrate digestion and absorption_Homo sapiens_hsa049730.61162387
73Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.60713294
74Linoleic acid metabolism_Homo sapiens_hsa005910.59873744
75Bladder cancer_Homo sapiens_hsa052190.59334149
76Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.59114173
77Phagosome_Homo sapiens_hsa041450.58287901
78Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.57718471
79African trypanosomiasis_Homo sapiens_hsa051430.57701688
80Viral carcinogenesis_Homo sapiens_hsa052030.57660382
81Prolactin signaling pathway_Homo sapiens_hsa049170.57239992
82Platelet activation_Homo sapiens_hsa046110.52890845
83Ether lipid metabolism_Homo sapiens_hsa005650.50342603
84Endometrial cancer_Homo sapiens_hsa052130.49983257
85Acute myeloid leukemia_Homo sapiens_hsa052210.49251678
86Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.48897100
87Vitamin digestion and absorption_Homo sapiens_hsa049770.47675206
88Homologous recombination_Homo sapiens_hsa034400.47442967
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47306364
90Thyroid hormone synthesis_Homo sapiens_hsa049180.46982362
91VEGF signaling pathway_Homo sapiens_hsa043700.46368487
92Folate biosynthesis_Homo sapiens_hsa007900.46067785
93Sphingolipid metabolism_Homo sapiens_hsa006000.45715770
94Renal cell carcinoma_Homo sapiens_hsa052110.45435224
95Staphylococcus aureus infection_Homo sapiens_hsa051500.44438503
96Pancreatic cancer_Homo sapiens_hsa052120.43742889
97Long-term potentiation_Homo sapiens_hsa047200.43032071
98Vibrio cholerae infection_Homo sapiens_hsa051100.42638005
99Mineral absorption_Homo sapiens_hsa049780.41864877
100Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.41512408
101FoxO signaling pathway_Homo sapiens_hsa040680.40401480
102Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.39891412
103Choline metabolism in cancer_Homo sapiens_hsa052310.39788001
104Protein digestion and absorption_Homo sapiens_hsa049740.37352174
105Hepatitis C_Homo sapiens_hsa051600.37308262
106Sulfur relay system_Homo sapiens_hsa041220.37284654
107Complement and coagulation cascades_Homo sapiens_hsa046100.35863202
108Chronic myeloid leukemia_Homo sapiens_hsa052200.35744126
109Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.35506045
110TNF signaling pathway_Homo sapiens_hsa046680.35085867
111Maturity onset diabetes of the young_Homo sapiens_hsa049500.33688358
112p53 signaling pathway_Homo sapiens_hsa041150.33612462
113Caffeine metabolism_Homo sapiens_hsa002320.32505367
114AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.32258914
115Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.32073962
116Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.31851227
117Drug metabolism - other enzymes_Homo sapiens_hsa009830.29820775
118Nucleotide excision repair_Homo sapiens_hsa034200.28971401
119Notch signaling pathway_Homo sapiens_hsa043300.27670256
120Spliceosome_Homo sapiens_hsa030400.25511083
121Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.25178738
122Small cell lung cancer_Homo sapiens_hsa052220.21884896
123Prostate cancer_Homo sapiens_hsa052150.21456598
124Graft-versus-host disease_Homo sapiens_hsa053320.20591760
125Glioma_Homo sapiens_hsa052140.20224786
126Systemic lupus erythematosus_Homo sapiens_hsa053220.17716710
127Pyrimidine metabolism_Homo sapiens_hsa002400.17211974
128Pentose phosphate pathway_Homo sapiens_hsa000300.16813197
129Phosphatidylinositol signaling system_Homo sapiens_hsa040700.15452561
130Insulin resistance_Homo sapiens_hsa049310.15039649
131Phenylalanine metabolism_Homo sapiens_hsa003600.14693339
132Lysosome_Homo sapiens_hsa041420.13528168
133Salmonella infection_Homo sapiens_hsa051320.11710624
134Inositol phosphate metabolism_Homo sapiens_hsa005620.10767859
135MAPK signaling pathway_Homo sapiens_hsa040100.10504159
136Transcriptional misregulation in cancer_Homo sapiens_hsa052020.10376894
137Aldosterone synthesis and secretion_Homo sapiens_hsa049250.10291235

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »