

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | B cell receptor signaling pathway (GO:0050853) | 7.17406277 |
| 2 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.72593015 |
| 3 | positive regulation of B cell differentiation (GO:0045579) | 5.70804515 |
| 4 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 5.48398622 |
| 5 | gonadal mesoderm development (GO:0007506) | 5.35395472 |
| 6 | B cell proliferation (GO:0042100) | 5.26465352 |
| 7 | immunoglobulin mediated immune response (GO:0016064) | 5.02169706 |
| 8 | production of molecular mediator involved in inflammatory response (GO:0002532) | 4.94933653 |
| 9 | B cell homeostasis (GO:0001782) | 4.94367288 |
| 10 | regulation of B cell differentiation (GO:0045577) | 4.92707888 |
| 11 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.89611663 |
| 12 | positive thymic T cell selection (GO:0045059) | 4.63583362 |
| 13 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.53259780 |
| 14 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 4.34885245 |
| 15 | * complement activation, classical pathway (GO:0006958) | 4.26992996 |
| 16 | negative regulation of B cell proliferation (GO:0030889) | 4.23410292 |
| 17 | regulation of antigen processing and presentation (GO:0002577) | 4.18215435 |
| 18 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.17099979 |
| 19 | defense response to protozoan (GO:0042832) | 4.17013133 |
| 20 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.14226232 |
| 21 | replicative senescence (GO:0090399) | 4.00393976 |
| 22 | detection of bacterium (GO:0016045) | 3.99430819 |
| 23 | regulation of B cell proliferation (GO:0030888) | 3.97927667 |
| 24 | positive regulation of respiratory burst (GO:0060267) | 3.93886302 |
| 25 | B cell mediated immunity (GO:0019724) | 3.93021657 |
| 26 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.85673456 |
| 27 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.82163723 |
| 28 | positive regulation of CREB transcription factor activity (GO:0032793) | 3.79353710 |
| 29 | cytidine metabolic process (GO:0046087) | 3.76474024 |
| 30 | cytidine catabolic process (GO:0006216) | 3.76474024 |
| 31 | cytidine deamination (GO:0009972) | 3.76474024 |
| 32 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.76191523 |
| 33 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.66658174 |
| 34 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.66157104 |
| 35 | detection of other organism (GO:0098543) | 3.65551953 |
| 36 | Peyers patch development (GO:0048541) | 3.65484718 |
| 37 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.65484718 |
| 38 | * humoral immune response (GO:0006959) | 3.61688705 |
| 39 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.61465444 |
| 40 | DNA deamination (GO:0045006) | 3.60409025 |
| 41 | cellular hyperosmotic response (GO:0071474) | 3.58884760 |
| 42 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.58714467 |
| 43 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.55002009 |
| 44 | positive regulation of antigen processing and presentation (GO:0002579) | 3.54172814 |
| 45 | B cell activation (GO:0042113) | 3.52103668 |
| 46 | T cell lineage commitment (GO:0002360) | 3.51289471 |
| 47 | thymic T cell selection (GO:0045061) | 3.50234882 |
| 48 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.48655337 |
| 49 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.48655337 |
| 50 | T cell selection (GO:0045058) | 3.47779129 |
| 51 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.47380158 |
| 52 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 3.45632579 |
| 53 | regulation of fibroblast apoptotic process (GO:2000269) | 3.45528772 |
| 54 | positive regulation of B cell proliferation (GO:0030890) | 3.45356396 |
| 55 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.43971848 |
| 56 | positive regulation of protein homooligomerization (GO:0032464) | 3.42553719 |
| 57 | T cell costimulation (GO:0031295) | 3.42210630 |
| 58 | response to protozoan (GO:0001562) | 3.41760387 |
| 59 | lymphocyte costimulation (GO:0031294) | 3.37154616 |
| 60 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.36276775 |
| 61 | positive regulation of protein oligomerization (GO:0032461) | 3.33782630 |
| 62 | negative regulation of alpha-beta T cell activation (GO:0046636) | 3.31573449 |
| 63 | positive regulation of B cell activation (GO:0050871) | 3.30879770 |
| 64 | regulation of germinal center formation (GO:0002634) | 3.30455091 |
| 65 | * immune response-activating cell surface receptor signaling pathway (GO:0002429) | 3.29785534 |
| 66 | positive T cell selection (GO:0043368) | 3.28129398 |
| 67 | antibacterial humoral response (GO:0019731) | 3.24924355 |
| 68 | positive regulation of type 2 immune response (GO:0002830) | 3.18158442 |
| 69 | antimicrobial humoral response (GO:0019730) | 3.16860795 |
| 70 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.15161893 |
| 71 | * complement activation (GO:0006956) | 3.14624172 |
| 72 | regulation of respiratory burst (GO:0060263) | 3.13015105 |
| 73 | negative regulation of phagocytosis (GO:0050765) | 3.11314383 |
| 74 | regulation of gamma-delta T cell activation (GO:0046643) | 3.06234258 |
| 75 | dendritic cell migration (GO:0036336) | 3.05259088 |
| 76 | T cell migration (GO:0072678) | 3.02888448 |
| 77 | cellular response to type I interferon (GO:0071357) | 3.01023944 |
| 78 | type I interferon signaling pathway (GO:0060337) | 3.01023944 |
| 79 | dendritic cell chemotaxis (GO:0002407) | 3.00447605 |
| 80 | negative thymic T cell selection (GO:0045060) | 2.99992844 |
| 81 | response to type I interferon (GO:0034340) | 2.99213652 |
| 82 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 2.98491846 |
| 83 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.98348143 |
| 84 | positive regulation of chemokine secretion (GO:0090197) | 2.96229071 |
| 85 | lymphocyte homeostasis (GO:0002260) | 2.96116006 |
| 86 | cellular response to virus (GO:0098586) | 2.95890582 |
| 87 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.91757198 |
| 88 | positive regulation of interferon-alpha production (GO:0032727) | 2.88079156 |
| 89 | natural killer cell differentiation (GO:0001779) | 2.87419289 |
| 90 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.86602420 |
| 91 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.85724220 |
| 92 | regulation of B cell activation (GO:0050864) | 2.85469241 |
| 93 | regulation of alpha-beta T cell activation (GO:0046634) | 2.85079142 |
| 94 | positive regulation of alpha-beta T cell differentiation (GO:0046638) | 2.84560271 |
| 95 | leukocyte homeostasis (GO:0001776) | 2.83697761 |
| 96 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.83482644 |
| 97 | NIK/NF-kappaB signaling (GO:0038061) | 2.78842300 |
| 98 | negative T cell selection (GO:0043383) | 2.76802781 |
| 99 | regulation of alpha-beta T cell differentiation (GO:0046637) | 2.75835987 |
| 100 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 2.73233424 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 8.98125776 |
| 2 | MYC_22102868_ChIP-Seq_BL_Human | 5.02300335 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.86478240 |
| 4 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 3.76179281 |
| 5 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 3.63506526 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.47006076 |
| 7 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.28634454 |
| 8 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.18659943 |
| 9 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.14858285 |
| 10 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.92037292 |
| 11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.89940228 |
| 12 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.59004461 |
| 13 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.57576586 |
| 14 | MYB_26560356_Chip-Seq_TH2_Human | 2.43513294 |
| 15 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.41504234 |
| 16 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.35537778 |
| 17 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.32845192 |
| 18 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.31721048 |
| 19 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.27974844 |
| 20 | MYB_26560356_Chip-Seq_TH1_Human | 2.09360049 |
| 21 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.05411274 |
| 22 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.04140504 |
| 23 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.03032430 |
| 24 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.95898443 |
| 25 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.87764649 |
| 26 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.86234739 |
| 27 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.78858594 |
| 28 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.74297642 |
| 29 | MAF_26560356_Chip-Seq_TH1_Human | 1.70530152 |
| 30 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.63066499 |
| 31 | GATA3_26560356_Chip-Seq_TH2_Human | 1.54369070 |
| 32 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.53585609 |
| 33 | UTX_26944678_Chip-Seq_JUKART_Human | 1.52206796 |
| 34 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.48953214 |
| 35 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.48855690 |
| 36 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46802155 |
| 37 | MAF_26560356_Chip-Seq_TH2_Human | 1.44557515 |
| 38 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.44299984 |
| 39 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.42122617 |
| 40 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.41461191 |
| 41 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.41158501 |
| 42 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.37946927 |
| 43 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.34600016 |
| 44 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.32856094 |
| 45 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.28465883 |
| 46 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.27939644 |
| 47 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.27191312 |
| 48 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.26050431 |
| 49 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.24994029 |
| 50 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.22235523 |
| 51 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.21411053 |
| 52 | P300_27268052_Chip-Seq_Bcells_Human | 1.19076946 |
| 53 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.18520482 |
| 54 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.17704995 |
| 55 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.17251004 |
| 56 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.16358613 |
| 57 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15338165 |
| 58 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15255882 |
| 59 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.14572700 |
| 60 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.13650483 |
| 61 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.07429526 |
| 62 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.07111271 |
| 63 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.06977714 |
| 64 | SPI1_23127762_ChIP-Seq_K562_Human | 1.05298323 |
| 65 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.04486042 |
| 66 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.02837266 |
| 67 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.02816721 |
| 68 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02483237 |
| 69 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.00750333 |
| 70 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 0.98691845 |
| 71 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.98513078 |
| 72 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.98382944 |
| 73 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.96779448 |
| 74 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.95506661 |
| 75 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.92760594 |
| 76 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.90577953 |
| 77 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87066610 |
| 78 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.87054979 |
| 79 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.86774663 |
| 80 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.84799449 |
| 81 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.84670170 |
| 82 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.84255808 |
| 83 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.83798538 |
| 84 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.82583948 |
| 85 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.79580068 |
| 86 | GATA3_26560356_Chip-Seq_TH1_Human | 0.79265991 |
| 87 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.79016813 |
| 88 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.78287311 |
| 89 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.77733391 |
| 90 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.77585877 |
| 91 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.77127401 |
| 92 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.76721119 |
| 93 | FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.76096553 |
| 94 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.75862353 |
| 95 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 0.75110432 |
| 96 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.75084568 |
| 97 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.74245273 |
| 98 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.73377101 |
| 99 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.73114467 |
| 100 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.72959626 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 5.07524671 |
| 2 | MP0005387_immune_system_phenotype | 4.36541403 |
| 3 | MP0001790_abnormal_immune_system | 4.36541403 |
| 4 | MP0001800_abnormal_humoral_immune | 4.22259632 |
| 5 | MP0002138_abnormal_hepatobiliary_system | 3.90370857 |
| 6 | MP0000685_abnormal_immune_system | 3.79404850 |
| 7 | MP0005671_abnormal_response_to | 3.38099543 |
| 8 | MP0002452_abnormal_antigen_presenting | 3.20632109 |
| 9 | MP0003303_peritoneal_inflammation | 3.14150386 |
| 10 | MP0003763_abnormal_thymus_physiology | 3.02113756 |
| 11 | MP0005000_abnormal_immune_tolerance | 2.91810385 |
| 12 | MP0002723_abnormal_immune_serum | 2.85859193 |
| 13 | MP0002420_abnormal_adaptive_immunity | 2.75892621 |
| 14 | MP0001819_abnormal_immune_cell | 2.69895454 |
| 15 | MP0002166_altered_tumor_susceptibility | 2.53414783 |
| 16 | MP0002398_abnormal_bone_marrow | 2.52908639 |
| 17 | MP0000465_gastrointestinal_hemorrhage | 2.47070324 |
| 18 | MP0000716_abnormal_immune_system | 2.34824639 |
| 19 | MP0002148_abnormal_hypersensitivity_rea | 2.23905174 |
| 20 | MP0000689_abnormal_spleen_morphology | 2.13969411 |
| 21 | MP0002396_abnormal_hematopoietic_system | 2.12735200 |
| 22 | MP0005025_abnormal_response_to | 2.04224974 |
| 23 | MP0010155_abnormal_intestine_physiology | 2.01646638 |
| 24 | MP0002429_abnormal_blood_cell | 1.91769162 |
| 25 | MP0001873_stomach_inflammation | 1.86306706 |
| 26 | MP0009785_altered_susceptibility_to | 1.79714540 |
| 27 | MP0002006_tumorigenesis | 1.74434178 |
| 28 | MP0005310_abnormal_salivary_gland | 1.74412089 |
| 29 | MP0003045_fibrosis | 1.69941896 |
| 30 | MP0002722_abnormal_immune_system | 1.68200428 |
| 31 | MP0003436_decreased_susceptibility_to | 1.65733050 |
| 32 | MP0001845_abnormal_inflammatory_respons | 1.59663912 |
| 33 | MP0002419_abnormal_innate_immunity | 1.54542182 |
| 34 | MP0003183_abnormal_peptide_metabolism | 1.51964979 |
| 35 | MP0009333_abnormal_splenocyte_physiolog | 1.51119252 |
| 36 | MP0002405_respiratory_system_inflammati | 1.49759569 |
| 37 | MP0003172_abnormal_lysosome_physiology | 1.44621326 |
| 38 | MP0000490_abnormal_crypts_of | 1.42368369 |
| 39 | MP0005360_urolithiasis | 1.40941224 |
| 40 | MP0002139_abnormal_hepatobiliary_system | 1.40604858 |
| 41 | MP0010234_abnormal_vibrissa_follicle | 1.40187562 |
| 42 | MP0001348_abnormal_lacrimal_gland | 1.39252265 |
| 43 | MP0000703_abnormal_thymus_morphology | 1.34854224 |
| 44 | MP0001986_abnormal_taste_sensitivity | 1.32742263 |
| 45 | MP0010094_abnormal_chromosome_stability | 1.31632800 |
| 46 | MP0003724_increased_susceptibility_to | 1.27225665 |
| 47 | MP0009278_abnormal_bone_marrow | 1.24907076 |
| 48 | MP0001663_abnormal_digestive_system | 1.19876678 |
| 49 | MP0003866_abnormal_defecation | 1.19150606 |
| 50 | MP0005075_abnormal_melanosome_morpholog | 1.15942134 |
| 51 | MP0002019_abnormal_tumor_incidence | 1.12698278 |
| 52 | MP0005464_abnormal_platelet_physiology | 1.10746407 |
| 53 | MP0002009_preneoplasia | 1.10455962 |
| 54 | MP0002163_abnormal_gland_morphology | 1.08246114 |
| 55 | MP0002136_abnormal_kidney_physiology | 1.05248304 |
| 56 | MP0004808_abnormal_hematopoietic_stem | 1.02931591 |
| 57 | MP0004947_skin_inflammation | 1.02137421 |
| 58 | MP0001853_heart_inflammation | 0.99354125 |
| 59 | MP0005451_abnormal_body_composition | 0.98976847 |
| 60 | MP0003693_abnormal_embryo_hatching | 0.98054013 |
| 61 | MP0006036_abnormal_mitochondrial_physio | 0.91439541 |
| 62 | MP0002796_impaired_skin_barrier | 0.90075933 |
| 63 | MP0008004_abnormal_stomach_pH | 0.89104770 |
| 64 | MP0008877_abnormal_DNA_methylation | 0.87325059 |
| 65 | MP0008469_abnormal_protein_level | 0.85904701 |
| 66 | MP0005381_digestive/alimentary_phenotyp | 0.84970005 |
| 67 | MP0003077_abnormal_cell_cycle | 0.84783603 |
| 68 | MP0003111_abnormal_nucleus_morphology | 0.84772283 |
| 69 | MP0002928_abnormal_bile_duct | 0.84714430 |
| 70 | MP0005501_abnormal_skin_physiology | 0.83817484 |
| 71 | MP0001764_abnormal_homeostasis | 0.80284914 |
| 72 | MP0001661_extended_life_span | 0.79327075 |
| 73 | MP0003786_premature_aging | 0.76204197 |
| 74 | MP0008874_decreased_physiological_sensi | 0.75026891 |
| 75 | MP0004381_abnormal_hair_follicle | 0.74560287 |
| 76 | MP0004264_abnormal_extraembryonic_tissu | 0.74393878 |
| 77 | MP0003806_abnormal_nucleotide_metabolis | 0.73625401 |
| 78 | MP0009643_abnormal_urine_homeostasis | 0.72941844 |
| 79 | MP0005085_abnormal_gallbladder_physiolo | 0.69910059 |
| 80 | MP0005379_endocrine/exocrine_gland_phen | 0.69348062 |
| 81 | MP0000372_irregular_coat_pigmentation | 0.69291679 |
| 82 | MP0001666_abnormal_nutrient_absorption | 0.68790408 |
| 83 | MP0003300_gastrointestinal_ulcer | 0.68185553 |
| 84 | MP0000371_diluted_coat_color | 0.64494296 |
| 85 | MP0003868_abnormal_feces_composition | 0.62917235 |
| 86 | MP0000249_abnormal_blood_vessel | 0.62457841 |
| 87 | MP0004145_abnormal_muscle_electrophysio | 0.61433238 |
| 88 | MP0002693_abnormal_pancreas_physiology | 0.61100147 |
| 89 | MP0004883_abnormal_blood_vessel | 0.59580655 |
| 90 | MP0003252_abnormal_bile_duct | 0.58701552 |
| 91 | MP0001765_abnormal_ion_homeostasis | 0.58440694 |
| 92 | MP0005084_abnormal_gallbladder_morpholo | 0.58137169 |
| 93 | MP0008057_abnormal_DNA_replication | 0.57567813 |
| 94 | MP0000015_abnormal_ear_pigmentation | 0.54424983 |
| 95 | MP0005645_abnormal_hypothalamus_physiol | 0.54396340 |
| 96 | MP0003646_muscle_fatigue | 0.53809037 |
| 97 | MP0000477_abnormal_intestine_morphology | 0.51124058 |
| 98 | MP0009764_decreased_sensitivity_to | 0.50805425 |
| 99 | MP0001533_abnormal_skeleton_physiology | 0.49979379 |
| 100 | MP0008872_abnormal_physiological_respon | 0.49155512 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Agammaglobulinemia (HP:0004432) | 9.38318712 |
| 2 | Gastrointestinal stroma tumor (HP:0100723) | 8.38584495 |
| 3 | Recurrent sinusitis (HP:0011108) | 6.17326796 |
| 4 | Verrucae (HP:0200043) | 5.86161416 |
| 5 | Papilloma (HP:0012740) | 5.86161416 |
| 6 | Recurrent bronchitis (HP:0002837) | 5.58217397 |
| 7 | Cellulitis (HP:0100658) | 5.33893782 |
| 8 | Meningitis (HP:0001287) | 5.12288932 |
| 9 | Lymphopenia (HP:0001888) | 5.04301106 |
| 10 | Panhypogammaglobulinemia (HP:0003139) | 4.83469718 |
| 11 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 4.62006039 |
| 12 | Emphysema (HP:0002097) | 4.56071276 |
| 13 | Vasculitis (HP:0002633) | 4.50636072 |
| 14 | Abnormality of B cell number (HP:0010975) | 4.43224855 |
| 15 | Colitis (HP:0002583) | 4.40722381 |
| 16 | Recurrent pneumonia (HP:0006532) | 4.40020755 |
| 17 | Osteomyelitis (HP:0002754) | 4.34575884 |
| 18 | B lymphocytopenia (HP:0010976) | 4.34039570 |
| 19 | Recurrent viral infections (HP:0004429) | 4.14202122 |
| 20 | IgM deficiency (HP:0002850) | 4.07982970 |
| 21 | IgG deficiency (HP:0004315) | 3.89970416 |
| 22 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.86437604 |
| 23 | Chronic sinusitis (HP:0011109) | 3.71565480 |
| 24 | Restrictive lung disease (HP:0002091) | 3.71199835 |
| 25 | Recurrent lower respiratory tract infections (HP:0002783) | 3.68022513 |
| 26 | Sepsis (HP:0100806) | 3.53241815 |
| 27 | Bronchitis (HP:0012387) | 3.50873137 |
| 28 | Recurrent otitis media (HP:0000403) | 3.41112362 |
| 29 | Inflammation of the large intestine (HP:0002037) | 3.36039235 |
| 30 | Gastrointestinal inflammation (HP:0004386) | 3.24910605 |
| 31 | Mediastinal lymphadenopathy (HP:0100721) | 3.19709040 |
| 32 | Lymphoma (HP:0002665) | 3.13398647 |
| 33 | Skin rash (HP:0000988) | 3.12907835 |
| 34 | Recurrent fungal infections (HP:0002841) | 2.96645557 |
| 35 | Recurrent bacterial skin infections (HP:0005406) | 2.90267841 |
| 36 | IgA deficiency (HP:0002720) | 2.83367440 |
| 37 | Neutropenia (HP:0001875) | 2.68376535 |
| 38 | Leukopenia (HP:0001882) | 2.63093417 |
| 39 | Abnormality of the prostate (HP:0008775) | 2.61132420 |
| 40 | Stomatitis (HP:0010280) | 2.58730669 |
| 41 | Abnormality of T cell physiology (HP:0011840) | 2.53225918 |
| 42 | Abnormal biliary tract physiology (HP:0012439) | 2.43557937 |
| 43 | Bile duct proliferation (HP:0001408) | 2.43557937 |
| 44 | Dehydration (HP:0001944) | 2.37127272 |
| 45 | Recurrent abscess formation (HP:0002722) | 2.31312301 |
| 46 | Hypoplasia of the thymus (HP:0000778) | 2.31184407 |
| 47 | Viral hepatitis (HP:0006562) | 2.31048954 |
| 48 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.29407712 |
| 49 | Malnutrition (HP:0004395) | 2.23359997 |
| 50 | Abnormality of T cells (HP:0002843) | 2.20933024 |
| 51 | Pulmonary infiltrates (HP:0002113) | 2.20092463 |
| 52 | Chronic obstructive pulmonary disease (HP:0006510) | 2.19361298 |
| 53 | Obstructive lung disease (HP:0006536) | 2.19361298 |
| 54 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.18761582 |
| 55 | Recurrent cutaneous fungal infections (HP:0011370) | 2.18761582 |
| 56 | Eczematoid dermatitis (HP:0000976) | 2.17805824 |
| 57 | Facial hemangioma (HP:0000329) | 2.17607045 |
| 58 | Recurrent skin infections (HP:0001581) | 2.14651770 |
| 59 | Chronic otitis media (HP:0000389) | 2.12500915 |
| 60 | Decreased circulating renin level (HP:0003351) | 2.09037942 |
| 61 | Encephalitis (HP:0002383) | 2.06852313 |
| 62 | Abnormality of the fingertips (HP:0001211) | 2.06385231 |
| 63 | Skin ulcer (HP:0200042) | 2.02979400 |
| 64 | Clubbing of toes (HP:0100760) | 2.02601637 |
| 65 | Urticaria (HP:0001025) | 2.01868845 |
| 66 | Premature loss of primary teeth (HP:0006323) | 1.99589804 |
| 67 | Increased IgE level (HP:0003212) | 1.95434515 |
| 68 | Pustule (HP:0200039) | 1.94158734 |
| 69 | Homocystinuria (HP:0002156) | 1.90870248 |
| 70 | Abnormality of homocysteine metabolism (HP:0010919) | 1.90870248 |
| 71 | Asplenia (HP:0001746) | 1.87182219 |
| 72 | 3-Methylglutaconic aciduria (HP:0003535) | 1.83546274 |
| 73 | Arthralgia (HP:0002829) | 1.79730676 |
| 74 | Chest pain (HP:0100749) | 1.77811576 |
| 75 | Prostate neoplasm (HP:0100787) | 1.77796613 |
| 76 | Congenital stationary night blindness (HP:0007642) | 1.77510303 |
| 77 | Elevated hepatic transaminases (HP:0002910) | 1.75274908 |
| 78 | Acrocyanosis (HP:0001063) | 1.75081932 |
| 79 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.73086254 |
| 80 | Eosinophilia (HP:0001880) | 1.72061261 |
| 81 | Parakeratosis (HP:0001036) | 1.69349028 |
| 82 | Hyperactive renin-angiotensin system (HP:0000841) | 1.68528021 |
| 83 | Chronic diarrhea (HP:0002028) | 1.66616796 |
| 84 | Hypertensive crisis (HP:0100735) | 1.66012532 |
| 85 | Basal cell carcinoma (HP:0002671) | 1.63273039 |
| 86 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.62459504 |
| 87 | Abnormality of male internal genitalia (HP:0000022) | 1.61534107 |
| 88 | Gastrointestinal infarctions (HP:0005244) | 1.60730435 |
| 89 | Hypoproteinemia (HP:0003075) | 1.60712287 |
| 90 | Pulmonary fibrosis (HP:0002206) | 1.60045527 |
| 91 | Dicarboxylic aciduria (HP:0003215) | 1.58732011 |
| 92 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.58732011 |
| 93 | Abnormality of the pleura (HP:0002103) | 1.58196355 |
| 94 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.57729230 |
| 95 | Xerostomia (HP:0000217) | 1.54752737 |
| 96 | Thoracic kyphosis (HP:0002942) | 1.52561519 |
| 97 | Paralysis (HP:0003470) | 1.52129258 |
| 98 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.52007738 |
| 99 | Albinism (HP:0001022) | 1.50788415 |
| 100 | Abnormality of T cell number (HP:0011839) | 1.50094912 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K10 | 5.49979433 |
| 2 | RIPK4 | 5.27506456 |
| 3 | MAP4K1 | 4.42481912 |
| 4 | BMPR2 | 3.61283856 |
| 5 | PRPF4B | 3.42773383 |
| 6 | ERN1 | 3.35092374 |
| 7 | TAOK3 | 3.23260124 |
| 8 | BLK | 3.18129865 |
| 9 | SMG1 | 2.65788740 |
| 10 | SYK | 2.53825593 |
| 11 | EIF2AK3 | 2.50502646 |
| 12 | VRK2 | 2.41958549 |
| 13 | BTK | 2.33057399 |
| 14 | GRK6 | 2.28461669 |
| 15 | EIF2AK1 | 2.12631126 |
| 16 | CDK19 | 1.46350875 |
| 17 | TYK2 | 1.43686158 |
| 18 | LYN | 1.42524771 |
| 19 | TAF1 | 1.40356602 |
| 20 | IRAK4 | 1.38036984 |
| 21 | PIK3CG | 1.37261409 |
| 22 | CSF1R | 1.33251976 |
| 23 | NEK9 | 1.31337643 |
| 24 | FES | 1.26083107 |
| 25 | PRKD2 | 1.18333886 |
| 26 | IKBKB | 1.15743496 |
| 27 | TAOK2 | 1.13155782 |
| 28 | GRK1 | 1.11069675 |
| 29 | IRAK3 | 1.10317921 |
| 30 | MST4 | 1.05723403 |
| 31 | CDK4 | 1.05598938 |
| 32 | SIK2 | 1.04876570 |
| 33 | MAPK11 | 1.01487474 |
| 34 | MELK | 1.01257639 |
| 35 | SIK3 | 0.98190663 |
| 36 | PRKCI | 0.89681409 |
| 37 | IRAK2 | 0.88316285 |
| 38 | CDK9 | 0.86945638 |
| 39 | CDK8 | 0.86915504 |
| 40 | CCNB1 | 0.86011972 |
| 41 | PIM1 | 0.82262562 |
| 42 | CSK | 0.81662515 |
| 43 | ITK | 0.81252157 |
| 44 | TEC | 0.80426431 |
| 45 | HCK | 0.78596221 |
| 46 | HIPK2 | 0.76612278 |
| 47 | PINK1 | 0.73315113 |
| 48 | JAK3 | 0.68208220 |
| 49 | TBK1 | 0.65773819 |
| 50 | PRKCQ | 0.63087140 |
| 51 | MARK2 | 0.61534700 |
| 52 | TNK2 | 0.61252487 |
| 53 | STK11 | 0.61107585 |
| 54 | OXSR1 | 0.59731338 |
| 55 | IKBKE | 0.56120728 |
| 56 | LRRK2 | 0.56088962 |
| 57 | LCK | 0.53228874 |
| 58 | BUB1 | 0.51841286 |
| 59 | VRK1 | 0.50705508 |
| 60 | EIF2AK2 | 0.46589473 |
| 61 | IRAK1 | 0.46393863 |
| 62 | STK39 | 0.45500621 |
| 63 | MAPK4 | 0.45097603 |
| 64 | MAPKAPK2 | 0.44959477 |
| 65 | STK10 | 0.43501645 |
| 66 | MAPK12 | 0.43394269 |
| 67 | STK24 | 0.41942475 |
| 68 | MAP2K2 | 0.41707586 |
| 69 | ATR | 0.40539821 |
| 70 | MAPK7 | 0.40433021 |
| 71 | EEF2K | 0.39936889 |
| 72 | MAP3K14 | 0.39579245 |
| 73 | MAP3K1 | 0.38864978 |
| 74 | CDK3 | 0.34768951 |
| 75 | PRKD1 | 0.34240982 |
| 76 | PDK1 | 0.33409584 |
| 77 | STK4 | 0.33329786 |
| 78 | TAOK1 | 0.33115124 |
| 79 | MAPKAPK5 | 0.32621949 |
| 80 | CHUK | 0.31396223 |
| 81 | PIM2 | 0.28731217 |
| 82 | DAPK1 | 0.28619498 |
| 83 | CHEK1 | 0.27472343 |
| 84 | PDPK1 | 0.26649256 |
| 85 | MAP3K13 | 0.25920564 |
| 86 | KIT | 0.25718656 |
| 87 | DYRK1B | 0.25404624 |
| 88 | ABL1 | 0.25310373 |
| 89 | MAPK9 | 0.24415340 |
| 90 | RPS6KB1 | 0.23946217 |
| 91 | PRKCD | 0.23708409 |
| 92 | CDC42BPA | 0.22764037 |
| 93 | CDK6 | 0.22267199 |
| 94 | AURKB | 0.20811546 |
| 95 | JAK1 | 0.20533888 |
| 96 | ZAP70 | 0.20452735 |
| 97 | MAP3K8 | 0.19788440 |
| 98 | INSR | 0.18509384 |
| 99 | MAP2K3 | 0.17612668 |
| 100 | PRKCZ | 0.17261712 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 5.61458696 |
| 2 | Asthma_Homo sapiens_hsa05310 | 4.96238511 |
| 3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.70912117 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 4.40190602 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 4.18278631 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.01678984 |
| 7 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 3.46697527 |
| 8 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 3.37461514 |
| 9 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.73365089 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.68859872 |
| 11 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.61256516 |
| 12 | Viral myocarditis_Homo sapiens_hsa05416 | 2.58666957 |
| 13 | Leishmaniasis_Homo sapiens_hsa05140 | 2.27080107 |
| 14 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.22272084 |
| 15 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.89625094 |
| 16 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.70214035 |
| 17 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.54161219 |
| 18 | DNA replication_Homo sapiens_hsa03030 | 1.53041346 |
| 19 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.35270180 |
| 20 | Influenza A_Homo sapiens_hsa05164 | 1.30242814 |
| 21 | Tuberculosis_Homo sapiens_hsa05152 | 1.23204258 |
| 22 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.20910700 |
| 23 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.20690639 |
| 24 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.18784651 |
| 25 | Mismatch repair_Homo sapiens_hsa03430 | 1.12144876 |
| 26 | Proteasome_Homo sapiens_hsa03050 | 1.00521388 |
| 27 | HTLV-I infection_Homo sapiens_hsa05166 | 1.00174720 |
| 28 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.97494491 |
| 29 | Homologous recombination_Homo sapiens_hsa03440 | 0.96577298 |
| 30 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.91868405 |
| 31 | Base excision repair_Homo sapiens_hsa03410 | 0.91534032 |
| 32 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.77271892 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.72529722 |
| 34 | Hepatitis B_Homo sapiens_hsa05161 | 0.68012402 |
| 35 | Measles_Homo sapiens_hsa05162 | 0.67510355 |
| 36 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67198670 |
| 37 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.65598876 |
| 38 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.61594423 |
| 39 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.60356924 |
| 40 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.58966949 |
| 41 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.57827633 |
| 42 | RNA degradation_Homo sapiens_hsa03018 | 0.56700317 |
| 43 | Apoptosis_Homo sapiens_hsa04210 | 0.55873440 |
| 44 | Phagosome_Homo sapiens_hsa04145 | 0.55036537 |
| 45 | Other glycan degradation_Homo sapiens_hsa00511 | 0.53244722 |
| 46 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.51674857 |
| 47 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.49975120 |
| 48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.48938472 |
| 49 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.47766660 |
| 50 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.46659340 |
| 51 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.45141222 |
| 52 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.44898767 |
| 53 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.44247105 |
| 54 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.43857159 |
| 55 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.41556841 |
| 56 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.40814420 |
| 57 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.40160679 |
| 58 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.39119437 |
| 59 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.39021934 |
| 60 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.38451165 |
| 61 | Ribosome_Homo sapiens_hsa03010 | 0.35853343 |
| 62 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.35177418 |
| 63 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.34558336 |
| 64 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.33859770 |
| 65 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.31108376 |
| 66 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.30098090 |
| 67 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.24674848 |
| 68 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.24640441 |
| 69 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.24528477 |
| 70 | Hepatitis C_Homo sapiens_hsa05160 | 0.23856257 |
| 71 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.22636199 |
| 72 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.21556707 |
| 73 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.21088715 |
| 74 | Protein export_Homo sapiens_hsa03060 | 0.20572632 |
| 75 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.18526002 |
| 76 | Spliceosome_Homo sapiens_hsa03040 | 0.18213367 |
| 77 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.16607154 |
| 78 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.16553981 |
| 79 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.15592637 |
| 80 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.15586856 |
| 81 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.14931146 |
| 82 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.14470974 |
| 83 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.14221819 |
| 84 | Phototransduction_Homo sapiens_hsa04744 | 0.12875225 |
| 85 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.11515671 |
| 86 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.10660754 |
| 87 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.10564486 |
| 88 | Cell cycle_Homo sapiens_hsa04110 | 0.10142982 |
| 89 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.09856611 |
| 90 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.09513422 |
| 91 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.07822084 |
| 92 | Platelet activation_Homo sapiens_hsa04611 | 0.07323076 |
| 93 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.07308633 |
| 94 | Pertussis_Homo sapiens_hsa05133 | 0.06245259 |
| 95 | ABC transporters_Homo sapiens_hsa02010 | 0.05252992 |
| 96 | Carbon metabolism_Homo sapiens_hsa01200 | 0.05199176 |
| 97 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.04531446 |
| 98 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.02937618 |
| 99 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.01708845 |
| 100 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | -0.0019346 |

