IGLJ3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1humoral immune response (GO:0006959)9.18255613
2keratinization (GO:0031424)8.10219381
3negative regulation of mast cell activation (GO:0033004)6.44966491
4positive regulation of respiratory burst (GO:0060267)6.44752330
5signal peptide processing (GO:0006465)6.09050109
6negative regulation of glucose import (GO:0046325)5.96729855
7immune response-activating cell surface receptor signaling pathway (GO:0002429)5.94246786
8cytidine deamination (GO:0009972)5.79521353
9cytidine metabolic process (GO:0046087)5.79521353
10cytidine catabolic process (GO:0006216)5.79521353
11B cell receptor signaling pathway (GO:0050853)5.00326618
12regulation of glucose import in response to insulin stimulus (GO:2001273)4.97593449
13detection of bacterium (GO:0016045)4.97575367
14lung lobe morphogenesis (GO:0060463)4.94782784
15Fc-epsilon receptor signaling pathway (GO:0038095)4.84728017
16detection of other organism (GO:0098543)4.81934571
17phenylpropanoid metabolic process (GO:0009698)4.80024813
18negative regulation of glucose transport (GO:0010829)4.78014027
19Fc receptor signaling pathway (GO:0038093)4.74076250
20glomerular filtration (GO:0003094)4.70001255
21DNA deamination (GO:0045006)4.64309957
22regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)4.58279433
23polarized epithelial cell differentiation (GO:0030859)4.56148098
24establishment of skin barrier (GO:0061436)4.54471276
25respiratory tube development (GO:0030323)4.50558893
26negative regulation of B cell proliferation (GO:0030889)4.37795275
27immunoglobulin mediated immune response (GO:0016064)4.33124090
28antigen processing and presentation of endogenous antigen (GO:0019883)4.25321939
29lung vasculature development (GO:0060426)4.20998715
30immune response-regulating cell surface receptor signaling pathway (GO:0002768)4.20047935
31regulation of respiratory burst (GO:0060263)4.16283636
32positive regulation of macrophage cytokine production (GO:0060907)4.15433321
33renal filtration (GO:0097205)4.12424681
34cellular response to zinc ion (GO:0071294)4.02296067
35antimicrobial humoral response (GO:0019730)4.01959936
36proline biosynthetic process (GO:0006561)3.97417113
37midgut development (GO:0007494)3.87874350
38B cell mediated immunity (GO:0019724)3.87536346
39pyrimidine ribonucleoside catabolic process (GO:0046133)3.80408730
40regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.79767486
41antibacterial humoral response (GO:0019731)3.75515550
42regulation of B cell proliferation (GO:0030888)3.73890913
43regulation of dendritic cell antigen processing and presentation (GO:0002604)3.73502132
44negative regulation of viral release from host cell (GO:1902187)3.73397090
45regulation of water loss via skin (GO:0033561)3.73387720
46T cell migration (GO:0072678)3.70843762
47immune response-activating signal transduction (GO:0002757)3.66438962
48regulation of B cell receptor signaling pathway (GO:0050855)3.64296870
49detection of external biotic stimulus (GO:0098581)3.62507131
50antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.44069672
51lipoxygenase pathway (GO:0019372)3.42143590
52positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.38059492
53regulation of mast cell degranulation (GO:0043304)3.37656429
54activation of immune response (GO:0002253)3.32967334
55negative thymic T cell selection (GO:0045060)3.22283877
56regulation of viral release from host cell (GO:1902186)3.19645140
57positive regulation of antigen processing and presentation (GO:0002579)3.18645553
58establishment of apical/basal cell polarity (GO:0035089)3.17923451
59regulation of antigen processing and presentation (GO:0002577)3.17146461
60B cell proliferation (GO:0042100)3.16895725
61positive regulation of B cell differentiation (GO:0045579)3.16331964
62interferon-gamma-mediated signaling pathway (GO:0060333)3.16247618
63positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610813.15766890
64L-fucose catabolic process (GO:0042355)3.12544025
65fucose catabolic process (GO:0019317)3.12544025
66L-fucose metabolic process (GO:0042354)3.12544025
67detection of biotic stimulus (GO:0009595)3.10403580
68regulation of interferon-beta biosynthetic process (GO:0045357)3.08239394
69regulation of mast cell activation involved in immune response (GO:0033006)3.08050697
70endocardial cushion development (GO:0003197)3.07588927
71regulation of natural killer cell differentiation (GO:0032823)3.06653196
72establishment of epithelial cell polarity (GO:0090162)3.05344139
73regulation of T-helper 1 cell differentiation (GO:0045625)3.04385700
74keratinocyte differentiation (GO:0030216)3.03880316
75regulation of alpha-beta T cell proliferation (GO:0046640)3.03051803
76peptide cross-linking (GO:0018149)3.02454101
77positive regulation of immunoglobulin production (GO:0002639)3.02263274
78complement activation, classical pathway (GO:0006958)27.3173007
79complement activation (GO:0006956)20.9670027
80regulation of B cell differentiation (GO:0045577)2.98784730
81negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.97029524
82positive regulation of T cell chemotaxis (GO:0010820)2.96639779
83regulation of T cell chemotaxis (GO:0010819)2.96639779
84cardiac left ventricle morphogenesis (GO:0003214)2.93306631
85production of molecular mediator involved in inflammatory response (GO:0002532)2.91810736
86negative T cell selection (GO:0043383)2.89222056
87negative regulation of leukocyte mediated immunity (GO:0002704)2.88576013
88lymphocyte migration (GO:0072676)2.87121205
89positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.86665262
90positive regulation of protein homooligomerization (GO:0032464)2.86442439
91negative regulation of interleukin-12 production (GO:0032695)2.84616119
92chaperone mediated protein folding requiring cofactor (GO:0051085)2.82975660
93macrophage activation involved in immune response (GO:0002281)2.81765386
94regulation of mast cell activation (GO:0033003)2.81180868
95NIK/NF-kappaB signaling (GO:0038061)2.80399530
96polyketide metabolic process (GO:0030638)2.78913851
97doxorubicin metabolic process (GO:0044598)2.78913851
98daunorubicin metabolic process (GO:0044597)2.78913851
99positive regulation by symbiont of host defense response (GO:0052509)2.78070772
100modulation by symbiont of host defense response (GO:0052031)2.78070772
101modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.78070772
102modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.78070772
103positive regulation by organism of defense response of other organism involved in symbiotic interact2.78070772
104modulation by symbiont of host immune response (GO:0052553)2.78070772
105mast cell activation (GO:0045576)2.75435180
106nucleoside diphosphate catabolic process (GO:0009134)2.74345317
107regulation of macrophage cytokine production (GO:0010935)2.73809973
108regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.73595916
109regulation of hypersensitivity (GO:0002883)2.71311501
110positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.70975194
111xenobiotic catabolic process (GO:0042178)2.69091055
112proline metabolic process (GO:0006560)2.69059128
113regulation of B cell apoptotic process (GO:0002902)2.68943193
114response to interleukin-15 (GO:0070672)2.68186625
115type I interferon signaling pathway (GO:0060337)2.67802883
116cellular response to type I interferon (GO:0071357)2.67802883
117respiratory burst (GO:0045730)2.67637392
118purine deoxyribonucleotide catabolic process (GO:0009155)2.67285345
119negative regulation of alpha-beta T cell activation (GO:0046636)2.67139187
120cellular response to interferon-gamma (GO:0071346)2.64290502
121regulation of germinal center formation (GO:0002634)2.63995515
122tissue homeostasis (GO:0001894)2.61552068
123aldehyde catabolic process (GO:0046185)2.58648169
124negative regulation of B cell activation (GO:0050869)2.56078113
125cofactor catabolic process (GO:0051187)2.55882097
126regulation of B cell activation (GO:0050864)2.53346227
127somatic hypermutation of immunoglobulin genes (GO:0016446)2.47999100
128somatic diversification of immune receptors via somatic mutation (GO:0002566)2.47999100
129COPI coating of Golgi vesicle (GO:0048205)2.45948310
130Golgi transport vesicle coating (GO:0048200)2.45948310
131glutamine family amino acid biosynthetic process (GO:0009084)2.42845497
132negative regulation of cellular response to insulin stimulus (GO:1900077)2.34954483
133thymic T cell selection (GO:0045061)2.32877250
134benzene-containing compound metabolic process (GO:0042537)2.31659394
135ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)2.24074614
136regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)2.18519136
137positive regulation of production of molecular mediator of immune response (GO:0002702)2.16890943
138erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.16646506
139L-phenylalanine catabolic process (GO:0006559)2.16646506
140regulation of immunoglobulin production (GO:0002637)2.16267970
141protein N-linked glycosylation via asparagine (GO:0018279)2.16090649
142protein maturation by protein folding (GO:0022417)2.13355374
143negative regulation of B cell apoptotic process (GO:0002903)2.12907859
144peptidyl-asparagine modification (GO:0018196)2.11489846
145antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.10805348
146antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.10805348
147positive thymic T cell selection (GO:0045059)2.08871070
148regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.08012434
149primary alcohol catabolic process (GO:0034310)2.07640615
150antigen receptor-mediated signaling pathway (GO:0050851)2.07596000
151aromatic amino acid family catabolic process (GO:0009074)2.06679174
152attachment of spindle microtubules to kinetochore (GO:0008608)2.02792157
153regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.02580210
154negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.02379306
155I-kappaB phosphorylation (GO:0007252)2.01691881
156regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.00280134
157regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)2.00203900
158protein activation cascade (GO:0072376)13.6880519
159immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:000211.2453600
160Fc-gamma receptor signaling pathway (GO:0038094)11.2453600
161Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096)11.2453600
162Fc receptor mediated stimulatory signaling pathway (GO:0002431)11.1142244
163retina homeostasis (GO:0001895)10.2530767
164detection of molecule of bacterial origin (GO:0032490)1.98818137
165protein N-linked glycosylation (GO:0006487)1.96897119
166regulation of cytokine secretion involved in immune response (GO:0002739)1.96659773
167T cell selection (GO:0045058)1.94053796
168positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)1.93386530
169antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)1.92410428
170positive regulation of B cell proliferation (GO:0030890)1.92274768
171mast cell activation involved in immune response (GO:0002279)1.91599370
172mast cell degranulation (GO:0043303)1.91599370

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.66371479
2IRF8_21731497_ChIP-ChIP_J774_Mouse4.86712241
3IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.82627975
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.51510002
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human4.51374409
6STAT6_21828071_ChIP-Seq_BEAS2B_Human4.45066184
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.43259939
8FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.97194549
9SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.85651820
10ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.68068742
11E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human3.22200468
12BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.17969944
13RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human3.15278664
14MYC_22102868_ChIP-Seq_BL_Human3.11389915
15STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.85796039
16IKZF1_21737484_ChIP-ChIP_HCT116_Human2.70904099
17IRF8_27001747_Chip-Seq_BMDM_Mouse2.61405994
18MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.57950371
19ELF1_17652178_ChIP-ChIP_JURKAT_Human2.55324533
20NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.53820698
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.53646797
22E2F4_17652178_ChIP-ChIP_JURKAT_Human2.47368817
23DROSHA_22980978_ChIP-Seq_HELA_Human2.44518529
24E2F7_22180533_ChIP-Seq_HELA_Human2.41525274
25TP63_17297297_ChIP-ChIP_HaCaT_Human2.17723404
26PPARA_22158963_ChIP-Seq_LIVER_Mouse2.16678815
27STAT4_19710469_ChIP-ChIP_TH1__Mouse2.11476718
28GATA1_22025678_ChIP-Seq_K562_Human2.07124681
29EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.06988206
30RUNX_20019798_ChIP-Seq_JUKART_Human2.06784952
31EGR1_19374776_ChIP-ChIP_THP-1_Human2.03481782
32RXR_22158963_ChIP-Seq_LIVER_Mouse2.00687065
33MAF_26560356_Chip-Seq_TH1_Human2.00494729
34PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.94411731
35FLI1_27457419_Chip-Seq_LIVER_Mouse1.92691479
36PU.1_20513432_ChIP-Seq_Bcells_Mouse1.85009010
37GABP_17652178_ChIP-ChIP_JURKAT_Human1.77441242
38IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.75266424
39PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.71357825
40STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.69268493
41MYB_26560356_Chip-Seq_TH2_Human1.69040726
42PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.67595976
43GATA3_26560356_Chip-Seq_TH2_Human1.65613878
44VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.64911197
45LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.64000780
46SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.61519071
47MYB_26560356_Chip-Seq_TH1_Human1.57672331
48VDR_24763502_ChIP-Seq_THP-1_Human1.51946548
49EGR1_19032775_ChIP-ChIP_M12_Human1.50562510
50VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.47503640
51THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.47233322
52EGR1_23403033_ChIP-Seq_LIVER_Mouse1.46769441
53SCL_19346495_ChIP-Seq_HPC-7_Human1.46384310
54GATA3_27048872_Chip-Seq_THYMUS_Human1.45083686
55AR_21909140_ChIP-Seq_LNCAP_Human1.44275344
56SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.37737835
57BP1_19119308_ChIP-ChIP_Hs578T_Human1.37266791
58PCGF2_27294783_Chip-Seq_NPCs_Mouse1.34231167
59VDR_21846776_ChIP-Seq_THP-1_Human1.33736846
60NOTCH1_21737748_ChIP-Seq_TLL_Human1.30120917
61LXR_22158963_ChIP-Seq_LIVER_Mouse1.28055000
62UTX_26944678_Chip-Seq_JUKART_Human1.26202960
63TRIM28_21343339_ChIP-Seq_HEK293_Human1.25880606
64HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.25480348
65CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.24681516
66STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.23720810
67FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.23175053
68RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.22380107
69CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.21973518
70HOXB4_20404135_ChIP-ChIP_EML_Mouse1.21431415
71BRD4_27068464_Chip-Seq_AML-cells_Mouse1.21429754
72SMAD_19615063_ChIP-ChIP_OVARY_Human1.19824777
73* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.19137283
74TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.19007595
75NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.17833764
76FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.16686853
77LXR_22292898_ChIP-Seq_THP-1_Human1.16532520
78PCGF2_27294783_Chip-Seq_ESCs_Mouse1.14799704
79MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.14780929
80STAT1_20625510_ChIP-Seq_HELA_Human1.14474242
81NFE2_27457419_Chip-Seq_LIVER_Mouse1.14342812
82MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.12150172
83MYB_21317192_ChIP-Seq_ERMYB_Mouse1.11106179
84SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.10542559
85SPI1_23547873_ChIP-Seq_NB4_Human1.09630348
86GATA1_19941826_ChIP-Seq_K562_Human1.09324304
87VDR_23849224_ChIP-Seq_CD4+_Human1.08298135
88ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.07784396
89NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.07594059
90KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.04109462
91CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.04068674
92SUZ12_27294783_Chip-Seq_NPCs_Mouse1.03646966
93FOXM1_23109430_ChIP-Seq_U2OS_Human1.02223279
94CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02005744
95GATA1_22383799_ChIP-Seq_G1ME_Mouse1.00517114
96BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.99550630
97PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.99389459
98NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.98858183
99NRF2_20460467_ChIP-Seq_MEFs_Mouse0.98858183
100FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.98604556
101ERG_20517297_ChIP-Seq_VCAP_Human0.98125185
102ELK1_19687146_ChIP-ChIP_HELA_Human0.98038869
103SMRT_27268052_Chip-Seq_Bcells_Human0.97859373
104LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.97478278
105PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.97242804
106MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.96265207
107IGF1R_20145208_ChIP-Seq_DFB_Human0.96215605
108CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95036285
109TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.95024769
110GATA2_22383799_ChIP-Seq_G1ME_Mouse0.94663278
111FOXH1_21741376_ChIP-Seq_ESCs_Human0.93539938
112SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93428762
113FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.93097175
114PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.92753590
115SPI1_23127762_ChIP-Seq_K562_Human0.91215819
116CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91082762
117SALL4_22934838_ChIP-ChIP_CD34+_Human0.90313128
118E2F1_17053090_ChIP-ChIP_MCF-7_Human0.89931923
119TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89691306
120GATA2_19941826_ChIP-Seq_K562_Human0.89594092
121CIITA_25753668_ChIP-Seq_RAJI_Human0.88937777
122MAF_26560356_Chip-Seq_TH2_Human0.88783149
123VDR_24787735_ChIP-Seq_THP-1_Human0.88688832
124EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.87123251
125GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.86679474
126TAF2_19829295_ChIP-Seq_ESCs_Human0.85710531
127P63_26484246_Chip-Seq_KERATINOCYTES_Human0.85707104
128SPI1_20517297_ChIP-Seq_HL60_Human0.85646960
129P300_27268052_Chip-Seq_Bcells_Human0.85252196
130ELK3_25401928_ChIP-Seq_HUVEC_Human0.85035037
131HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.84799631
132PADI4_21655091_ChIP-ChIP_MCF-7_Human0.84610538
133RUNX1_22412390_ChIP-Seq_EML_Mouse0.84091533
134GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.83532377
135ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.83440755
136CREB1_15753290_ChIP-ChIP_HEK293T_Human0.83184281
137SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.82850528
138FOXP3_21729870_ChIP-Seq_TREG_Human0.82271410
139PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.81948822
140EST1_17652178_ChIP-ChIP_JURKAT_Human0.81940499
141SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.81437421
142BCL6_27268052_Chip-Seq_Bcells_Human0.81345310
143PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.80610368
144Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.79925799
145CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.79010688
146GATA6_21074721_ChIP-Seq_CACO-2_Human0.78682722
147CEBPB_22108803_ChIP-Seq_LS180_Human0.78596934
148SMAD1_18555785_Chip-Seq_ESCs_Mouse0.78545912
149EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.78397577
150SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77054017
151NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.75939636

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation5.64011962
2MP0001800_abnormal_humoral_immune4.47470329
3MP0002796_impaired_skin_barrier3.81676459
4MP0005671_abnormal_response_to3.81365067
5MP0002138_abnormal_hepatobiliary_system3.78992878
6MP0003724_increased_susceptibility_to3.77387966
7MP0003303_peritoneal_inflammation3.33455531
8MP0001790_abnormal_immune_system3.29126642
9MP0005387_immune_system_phenotype3.29126642
10MP0002452_abnormal_antigen_presenting3.11893328
11MP0002876_abnormal_thyroid_physiology3.02500302
12MP0000685_abnormal_immune_system2.83706629
13MP0002723_abnormal_immune_serum2.73328024
14MP0005275_abnormal_skin_tensile2.68533018
15MP0006054_spinal_hemorrhage2.68476132
16MP0002148_abnormal_hypersensitivity_rea2.51552586
17MP0002420_abnormal_adaptive_immunity2.50885218
18MP0001819_abnormal_immune_cell2.45533727
19MP0005000_abnormal_immune_tolerance2.38765809
20MP0002139_abnormal_hepatobiliary_system2.37217651
21MP0002398_abnormal_bone_marrow2.27334528
22MP0000716_abnormal_immune_system2.24646225
23MP0002166_altered_tumor_susceptibility2.13525620
24MP0005501_abnormal_skin_physiology2.07470766
25MP0005360_urolithiasis1.94954004
26MP0010234_abnormal_vibrissa_follicle1.89593209
27MP0000689_abnormal_spleen_morphology1.87125662
28MP0005025_abnormal_response_to1.86911247
29MP0002429_abnormal_blood_cell1.80351978
30MP0002163_abnormal_gland_morphology1.77296646
31MP0002419_abnormal_innate_immunity1.76931204
32MP0005085_abnormal_gallbladder_physiolo1.70469074
33MP0002006_tumorigenesis1.65158280
34MP0004947_skin_inflammation1.64031022
35MP0004859_abnormal_synaptic_plasticity1.58596760
36MP0005310_abnormal_salivary_gland1.56956984
37MP0000579_abnormal_nail_morphology1.54379699
38MP0002722_abnormal_immune_system1.53909373
39MP0000920_abnormal_myelination1.52642711
40MP0001845_abnormal_inflammatory_respons1.52008375
41MP0003941_abnormal_skin_development1.50413001
42MP0006082_CNS_inflammation1.47486608
43MP0010094_abnormal_chromosome_stability1.45161763
44MP0004782_abnormal_surfactant_physiolog1.43600319
45MP0004145_abnormal_muscle_electrophysio1.41620440
46MP0002933_joint_inflammation1.41600079
47MP0005623_abnormal_meninges_morphology1.41517618
48MP0003879_abnormal_hair_cell1.34780853
49MP0001216_abnormal_epidermal_layer1.34148117
50MP0003436_decreased_susceptibility_to1.33120206
51MP0002405_respiratory_system_inflammati1.32552680
52MP0004510_myositis1.32047784
53MP0005166_decreased_susceptibility_to1.31276296
54MP0003693_abnormal_embryo_hatching1.29411447
55MP0009046_muscle_twitch1.27309607
56MP0003191_abnormal_cellular_cholesterol1.27273031
57MP0001348_abnormal_lacrimal_gland1.26771060
58MP0003075_altered_response_to1.26506907
59MP0001853_heart_inflammation1.24511835
60MP0003880_abnormal_central_pattern1.23807663
61MP0000465_gastrointestinal_hemorrhage1.23601161
62MP0002060_abnormal_skin_morphology1.21897313
63MP0009333_abnormal_splenocyte_physiolog1.21575464
64MP0005332_abnormal_amino_acid1.20749717
65MP0009785_altered_susceptibility_to1.18934207
66MP0008004_abnormal_stomach_pH1.18871723
67MP0003763_abnormal_thymus_physiology1.18423058
68MP0005083_abnormal_biliary_tract1.16558522
69MP0005584_abnormal_enzyme/coenzyme_acti1.14581784
70MP0000013_abnormal_adipose_tissue1.14520580
71MP0008569_lethality_at_weaning1.14338520
72MP0005379_endocrine/exocrine_gland_phen1.12549620
73MP0001879_abnormal_lymphatic_vessel1.12010982
74MP0002254_reproductive_system_inflammat1.06033685
75MP0010771_integument_phenotype1.01342391
76MP0004885_abnormal_endolymph1.00544581
77MP0006036_abnormal_mitochondrial_physio1.00280508
78MP0003045_fibrosis0.98081707
79MP0004264_abnormal_extraembryonic_tissu0.96915534
80MP0003690_abnormal_glial_cell0.95946279
81MP0003656_abnormal_erythrocyte_physiolo0.95615026
82MP0008875_abnormal_xenobiotic_pharmacok0.93592847
83MP0003300_gastrointestinal_ulcer0.93068705
84MP0008057_abnormal_DNA_replication0.91305890
85MP0004147_increased_porphyrin_level0.90625283
86MP0010155_abnormal_intestine_physiology0.90172349
87MP0000003_abnormal_adipose_tissue0.88850915
88MP0005464_abnormal_platelet_physiology0.88546284
89MP0002136_abnormal_kidney_physiology0.86262112
90MP0009764_decreased_sensitivity_to0.85808051
91MP0002277_abnormal_respiratory_mucosa0.85737061
92MP0001986_abnormal_taste_sensitivity0.85093970
93MP0003453_abnormal_keratinocyte_physiol0.85043612
94MP0003186_abnormal_redox_activity0.84157589
95MP0008469_abnormal_protein_level0.83778887
96MP0003806_abnormal_nucleotide_metabolis0.83451066
97MP0001873_stomach_inflammation0.82458983
98MP0010352_gastrointestinal_tract_polyps0.82403307
99MP0005365_abnormal_bile_salt0.82142826
100MP0003866_abnormal_defecation0.80923297
101MP0002396_abnormal_hematopoietic_system0.80740656
102MP0002019_abnormal_tumor_incidence0.80218269
103MP0000343_altered_response_to0.79290379
104MP0003448_altered_tumor_morphology0.79270972
105MP0003252_abnormal_bile_duct0.79209492
106MP0004134_abnormal_chest_morphology0.78767994
107MP0005165_increased_susceptibility_to0.78211211
108MP0000604_amyloidosis0.78173271
109MP0000609_abnormal_liver_physiology0.77694734
110MP0001346_abnormal_lacrimal_gland0.77614336
111MP0009643_abnormal_urine_homeostasis0.77459229
112MP0001501_abnormal_sleep_pattern0.74378238
113MP0004142_abnormal_muscle_tone0.73151087
114MP0003329_amyloid_beta_deposits0.72386618
115MP0001191_abnormal_skin_condition0.71305488
116MP0008872_abnormal_physiological_respon0.71161563
117MP0001663_abnormal_digestive_system0.70986503
118MP0002272_abnormal_nervous_system0.70272350
119MP0008438_abnormal_cutaneous_collagen0.69076999
120MP0010329_abnormal_lipoprotein_level0.68383844
121MP0005388_respiratory_system_phenotype0.67954407
122MP0002133_abnormal_respiratory_system0.67954407
123MP0001545_abnormal_hematopoietic_system0.66936543
124MP0005397_hematopoietic_system_phenotyp0.66936543
125MP0003786_premature_aging0.66422965
126MP0005023_abnormal_wound_healing0.65770251
127MP0000703_abnormal_thymus_morphology0.65332075
128MP0001666_abnormal_nutrient_absorption0.65274053
129MP0002873_normal_phenotype0.64334671
130MP0000377_abnormal_hair_follicle0.64184327
131MP0002169_no_abnormal_phenotype0.64174272
132MP0002064_seizures0.64016892
133MP0003635_abnormal_synaptic_transmissio0.63734727
134MP0009278_abnormal_bone_marrow0.63547188
135MP0009931_abnormal_skin_appearance0.62680288
136MP0001533_abnormal_skeleton_physiology0.62343211
137MP0002909_abnormal_adrenal_gland0.62144028
138MP0001177_atelectasis0.61915208
139MP0000613_abnormal_salivary_gland0.61484811
140MP0003868_abnormal_feces_composition0.60596584
141MP0005164_abnormal_response_to0.59759978
142MP0000367_abnormal_coat/_hair0.56701280
143MP0001851_eye_inflammation0.56612070
144MP0008058_abnormal_DNA_repair0.56197419
145MP0002168_other_aberrant_phenotype0.54746441
146MP0004957_abnormal_blastocyst_morpholog0.53178902
147MP0000249_abnormal_blood_vessel0.49686255

Predicted human phenotypes

RankGene SetZ-score
1Agammaglobulinemia (HP:0004432)8.29754944
2Abnormality of B cell number (HP:0010975)6.84032629
3B lymphocytopenia (HP:0010976)6.84032629
4Prostate neoplasm (HP:0100787)6.77522820
5Recurrent bronchitis (HP:0002837)6.25962701
6Recurrent sinusitis (HP:0011108)5.82305716
7Gastrointestinal stroma tumor (HP:0100723)5.49358792
8Cellulitis (HP:0100658)5.38559392
9Abnormality of nail color (HP:0100643)4.99801178
10Recurrent pneumonia (HP:0006532)4.84744653
11Papilloma (HP:0012740)4.79962472
12Verrucae (HP:0200043)4.79962472
13Abnormality of the prostate (HP:0008775)4.74664195
14Oral leukoplakia (HP:0002745)4.56405802
15Increased IgE level (HP:0003212)4.47203119
16IgM deficiency (HP:0002850)4.46837233
17Congenital nonbullous ichthyosiform erythroderma (HP:0007479)4.33469209
18Meningitis (HP:0001287)4.24928617
19Recurrent lower respiratory tract infections (HP:0002783)4.21585933
20Chronic sinusitis (HP:0011109)4.11859309
21Congenital ichthyosiform erythroderma (HP:0007431)4.05517860
22Abnormality of the pulmonary veins (HP:0011718)3.97895896
23Thyroiditis (HP:0100646)3.92900142
24IgG deficiency (HP:0004315)3.91400790
25Onycholysis (HP:0001806)3.70196091
26Abnormal umbilical cord blood vessels (HP:0011403)3.66597219
27Single umbilical artery (HP:0001195)3.66597219
28Abnormality of the fetal cardiovascular system (HP:0010948)3.66597219
29Recurrent viral infections (HP:0004429)3.65616953
30Colitis (HP:0002583)3.59288076
31Intestinal atresia (HP:0011100)3.46746443
32Bronchitis (HP:0012387)3.44429690
33Recurrent otitis media (HP:0000403)3.40742076
34Annular pancreas (HP:0001734)3.40625164
35Parakeratosis (HP:0001036)3.36848560
36Palmoplantar hyperkeratosis (HP:0000972)3.34729034
37IgA deficiency (HP:0002720)3.28694457
38Gangrene (HP:0100758)3.28431072
39Osteomyelitis (HP:0002754)3.25415501
40Alopecia of scalp (HP:0002293)3.24420888
41Elevated erythrocyte sedimentation rate (HP:0003565)3.23061973
42Erythroderma (HP:0001019)3.20113853
43Paralysis (HP:0003470)3.15086083
44Sepsis (HP:0100806)3.13157590
45Palmar hyperkeratosis (HP:0010765)3.09037664
46Panhypogammaglobulinemia (HP:0003139)3.05859505
47Erythema (HP:0010783)3.05649510
48Chronic otitis media (HP:0000389)3.01772278
49Urticaria (HP:0001025)3.00116284
50Abnormality of T cell number (HP:0011839)2.99234462
51Autoimmune thrombocytopenia (HP:0001973)2.98583732
52Abnormality of macrophages (HP:0004311)2.95286662
53Neonatal death (HP:0003811)2.91025443
54Skin rash (HP:0000988)2.89366000
55Premature loss of primary teeth (HP:0006323)2.89171258
56Abnormality of T cell physiology (HP:0011840)2.86629262
57Ectropion (HP:0000656)2.82347462
58Plantar hyperkeratosis (HP:0007556)2.81553440
59Vasculitis (HP:0002633)2.80469875
60Emphysema (HP:0002097)2.78916697
61Hypoplasia of the thymus (HP:0000778)2.78348025
62Corneal erosion (HP:0200020)2.77326578
63Xerostomia (HP:0000217)2.67914461
64Hydroureter (HP:0000072)2.67641373
65Interstitial pulmonary disease (HP:0006530)2.65672512
66Abnormality of T cells (HP:0002843)2.60127461
67Amniotic constriction ring (HP:0009775)2.59748667
68Abnormality of placental membranes (HP:0011409)2.59748667
69Combined immunodeficiency (HP:0005387)2.59182892
70Small epiphyses (HP:0010585)2.58253227
71Leukocytosis (HP:0001974)2.57166763
72Severe combined immunodeficiency (HP:0004430)2.53438648
73Abnormality of male internal genitalia (HP:0000022)2.52986046
74Mitral stenosis (HP:0001718)2.50184468
75Restrictive lung disease (HP:0002091)2.49711439
76Abnormality of cells of the lymphoid lineage (HP:0012140)2.49491330
77Myositis (HP:0100614)2.49456885
78T lymphocytopenia (HP:0005403)2.47894728
79Recurrent bacterial skin infections (HP:0005406)2.47529502
80Pustule (HP:0200039)2.47209272
81Recurrent abscess formation (HP:0002722)2.45682122
82Acute encephalopathy (HP:0006846)2.43763798
83Lymphopenia (HP:0001888)2.41809468
84Mucosal telangiectasiae (HP:0100579)2.39747493
85Acute necrotizing encephalopathy (HP:0006965)2.38753580
86Colon cancer (HP:0003003)2.37534379
87Inflammation of the large intestine (HP:0002037)2.35175855
88Abnormal lung lobation (HP:0002101)2.32364170
89Progressive macrocephaly (HP:0004481)2.31067362
90Amaurosis fugax (HP:0100576)2.28100685
91Abnormality of the umbilical cord (HP:0010881)2.27415165
92Pruritus (HP:0000989)2.27135018
93Vacuolated lymphocytes (HP:0001922)2.25655181
94Gastrointestinal inflammation (HP:0004386)2.22952786
95Acrocyanosis (HP:0001063)2.22679694
96Hypertensive crisis (HP:0100735)2.22197920
97Thick nail (HP:0001805)2.21807474
98Lymphoma (HP:0002665)2.20735674
99Recurrent fungal infections (HP:0002841)2.18139988
100Ridged nail (HP:0001807)2.17698571
101Abnormalities of placenta or umbilical cord (HP:0001194)2.17271489
102Pulmonary infiltrates (HP:0002113)2.13978170
103Sparse eyelashes (HP:0000653)2.10830742
104Deep venous thrombosis (HP:0002625)2.10657088
105Arthralgia (HP:0002829)2.08858609
106Abnormality of the intrinsic pathway (HP:0010989)2.08683798
107Chest pain (HP:0100749)2.08463923
108Eosinophilia (HP:0001880)2.08069530
109Recurrent gram-negative bacterial infections (HP:0005420)2.06223030
110Hypotrichosis (HP:0001006)2.03440540
111Abnormal mitochondria in muscle tissue (HP:0008316)2.01696392
112Increased IgM level (HP:0003496)2.01686316
113Clubbing of toes (HP:0100760)2.00881656
114Abnormality of the axillary hair (HP:0100134)2.00210540
115Abnormality of secondary sexual hair (HP:0009888)2.00210540
116Dehydration (HP:0001944)1.99783173
117Abnormal gallbladder morphology (HP:0012437)1.98774149
118Nonimmune hydrops fetalis (HP:0001790)1.98603400
119Hypoproteinemia (HP:0003075)1.98511488
120Meckel diverticulum (HP:0002245)1.96985354
121Abnormal foot bone ossification (HP:0010675)1.96510508
122Neoplasm of the lung (HP:0100526)1.95732060
123Hypoplastic left heart (HP:0004383)1.95555364
124Abnormality of the labia minora (HP:0012880)1.95413019
125Gastrointestinal infarctions (HP:0005244)1.95222870
126Cholelithiasis (HP:0001081)1.94115235
127Recurrent skin infections (HP:0001581)1.93930888
128Abnormal delayed hypersensitivity skin test (HP:0002963)1.93476119
129Keratoconjunctivitis (HP:0001096)1.92117014
130Skin ulcer (HP:0200042)1.91226453
131Limb hypertonia (HP:0002509)1.90579370
132Keratoconjunctivitis sicca (HP:0001097)1.90133848
133Autoimmune hemolytic anemia (HP:0001890)1.77543012
134Leukodystrophy (HP:0002415)1.77397691
135Abnormality of aromatic amino acid family metabolism (HP:0004338)1.77363511
136Neutropenia (HP:0001875)1.75535613
137Conjunctival hamartoma (HP:0100780)1.74996384
138Hepatocellular necrosis (HP:0001404)1.74963037
139Thrombocytosis (HP:0001894)1.72689096
140Hyperventilation (HP:0002883)1.69613150
141Camptodactyly of toe (HP:0001836)1.68550374
142Cerebral edema (HP:0002181)1.68296002
143Papilledema (HP:0001085)1.67890370
144Eczematoid dermatitis (HP:0000976)1.67197413
145Hypergammaglobulinemia (HP:0010702)1.66941219
146Metaphyseal cupping (HP:0003021)1.66807471
147Abnormality of monocarboxylic acid metabolism (HP:0010996)1.65965975
148Abnormal tarsal ossification (HP:0008369)1.65532512
149Exercise-induced myalgia (HP:0003738)1.64118569
150Intrahepatic cholestasis (HP:0001406)1.63803188
151Long clavicles (HP:0000890)1.62348364
152Abnormality of eosinophils (HP:0001879)1.61632492
153Abnormality of the lumbar spine (HP:0100712)1.60722298
154Irregular vertebral endplates (HP:0003301)1.60484670
155Leukopenia (HP:0001882)1.59016424
156Beaking of vertebral bodies (HP:0004568)1.58867535

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.32920412
2TAF14.34906039
3MAP4K14.30554146
4SMG14.07605382
5ERN13.31692954
6BUB13.10026559
7RIPK42.80305607
8SYK2.79785020
9EIF2AK12.60255910
10PRKCH2.53172313
11KIT2.22942682
12LYN2.20044075
13BMPR22.19493223
14BCKDK2.18577775
15IRAK42.18305264
16STK242.13939003
17MAP3K132.11983067
18CSF1R2.08607778
19CCNB12.07121422
20ZAK2.03875510
21TXK2.01517868
22GRK62.01158462
23MAP3K41.96424600
24MAP3K141.92572845
25TBK11.86921095
26FES1.83129431
27MST41.78544704
28BTK1.68215462
29ITK1.64755819
30PRKCQ1.62369806
31BLK1.60490599
32EIF2AK31.57090268
33BCR1.56821029
34TAOK31.54844844
35CLK11.53168292
36GRK11.52766042
37TYK21.50729100
38SIK21.50573109
39MAPKAPK51.48483220
40STK38L1.45942491
41FRK1.41983467
42NEK11.41714537
43TLK11.38802348
44FGFR21.36985855
45NME11.29740766
46PIK3CG1.23852965
47PRKCI1.20847686
48NEK21.14356050
49FGFR31.13363605
50IRAK31.13172462
51PLK31.12139758
52HCK1.04945770
53PIK3CA1.01772662
54CSNK1G31.01586962
55BMX1.00516742
56STK100.99750898
57MAP3K90.99483507
58PLK20.99012788
59IKBKB0.98837528
60TTN0.98761851
61SIK10.98427142
62BRSK10.96911670
63UHMK10.96118494
64MELK0.95656909
65NEK90.92489752
66EPHA30.91694783
67LCK0.90737979
68MATK0.90431536
69NME20.88619409
70PRKCD0.88527348
71OXSR10.88333555
72CSNK1A1L0.86962633
73EPHA40.84313536
74IRAK10.84195795
75FYN0.84065067
76JAK10.83760002
77NTRK30.79108580
78PKN10.78448921
79ARAF0.77475583
80CSNK1G20.76451977
81HIPK20.72995296
82PIM10.72271068
83MAPK120.70282335
84DAPK10.70065961
85DAPK30.68934576
86ZAP700.68624214
87TEC0.67647202
88PRKD10.67406558
89KSR20.65108789
90ADRBK20.64491895
91MAP3K50.64058630
92BMPR1B0.62947624
93CSK0.60222699
94CSNK1G10.59497285
95FGFR40.59316950
96TTK0.58680855
97LRRK20.58244455
98MAP3K30.57408523
99TGFBR20.56767079
100STK40.56520046
101MST1R0.56485900
102CAMKK10.54270559
103CDK90.53042875
104PRKCZ0.52032863
105CDK150.50363481
106RPS6KA60.49709191
107EIF2AK20.49603863
108CDC42BPA0.47779126
109STK30.47598706
110TGFBR10.46983238
111NUAK10.46583454
112ALK0.46172306
113DDR20.45818955
114LMTK20.45625988
115RPS6KC10.44546150
116RPS6KL10.44546150
117STK390.44200517
118CDK180.44188407
119STK160.43366658
120INSR0.42647014
121CDK140.40793424
122PRPF4B0.39781439
123MAPKAPK20.39290903
124PRKCG0.39134005
125MYLK0.38729204
126GRK50.38084531
127MAPK40.37868403
128MAP3K100.37599891
129CDK50.36982220
130DYRK1B0.36585928
131IKBKE0.35187701
132MAP3K80.35007394
133VRK10.34563564
134CAMK2A0.33875430
135CHUK0.31891658
136AURKB0.30683730
137CDK11A0.30365042
138JAK20.30235683
139JAK30.29604613
140MAP3K120.28805059
141FGR0.28143976
142MAPK70.26380202
143FER0.25450867
144MKNK20.25379248
145MAP2K60.23659963
146IGF1R0.22561328
147WEE10.22533019
148EPHB10.19289371
149MAP2K30.18918843
150ATR0.17465904

Predicted pathways (KEGG)

RankGene SetZ-score
1Intestinal immune network for IgA production_Homo sapiens_hsa046728.50553576
2Primary immunodeficiency_Homo sapiens_hsa053405.37284875
3Protein export_Homo sapiens_hsa030604.48152735
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.21141784
5B cell receptor signaling pathway_Homo sapiens_hsa046623.09624110
6Pantothenate and CoA biosynthesis_Homo sapiens_hsa007703.02541272
7Proteasome_Homo sapiens_hsa030502.16753241
8Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.16630798
9Systemic lupus erythematosus_Homo sapiens_hsa053221.95050190
10Rheumatoid arthritis_Homo sapiens_hsa053231.84899788
11Vitamin B6 metabolism_Homo sapiens_hsa007501.83700413
12DNA replication_Homo sapiens_hsa030301.73322960
13N-Glycan biosynthesis_Homo sapiens_hsa005101.67837325
14Allograft rejection_Homo sapiens_hsa053301.48476664
15Asthma_Homo sapiens_hsa053101.45333808
16Folate biosynthesis_Homo sapiens_hsa007901.45221485
17Primary bile acid biosynthesis_Homo sapiens_hsa001201.34446044
18Influenza A_Homo sapiens_hsa051641.32698206
19Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.32324054
20Non-homologous end-joining_Homo sapiens_hsa034501.27900812
21Antigen processing and presentation_Homo sapiens_hsa046121.26849789
22Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.24616842
23Arginine biosynthesis_Homo sapiens_hsa002201.23242957
242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.22791699
25Nitrogen metabolism_Homo sapiens_hsa009101.20488109
26alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.18508387
27Pyruvate metabolism_Homo sapiens_hsa006201.17511445
28Herpes simplex infection_Homo sapiens_hsa051681.12752509
29Phenylalanine metabolism_Homo sapiens_hsa003601.12221999
30Leishmaniasis_Homo sapiens_hsa051401.11656713
31Sulfur metabolism_Homo sapiens_hsa009201.10477078
32Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08016456
33Toxoplasmosis_Homo sapiens_hsa051451.07313723
34Homologous recombination_Homo sapiens_hsa034401.07298147
35Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.06271591
36Tryptophan metabolism_Homo sapiens_hsa003801.01939083
37Alzheimers disease_Homo sapiens_hsa050101.01934114
38Mismatch repair_Homo sapiens_hsa034301.01370030
39NF-kappa B signaling pathway_Homo sapiens_hsa040641.00292310
40Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.99294163
41Other glycan degradation_Homo sapiens_hsa005110.97601588
42Base excision repair_Homo sapiens_hsa034100.97361272
43Malaria_Homo sapiens_hsa051440.95840082
44Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.95663547
45Measles_Homo sapiens_hsa051620.95092723
46Staphylococcus aureus infection_Homo sapiens_hsa051500.87678918
47Linoleic acid metabolism_Homo sapiens_hsa005910.87310308
48Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.85262666
49Epstein-Barr virus infection_Homo sapiens_hsa051690.84328966
50Type I diabetes mellitus_Homo sapiens_hsa049400.84206597
51Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.83428696
52Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.82814072
53Oxidative phosphorylation_Homo sapiens_hsa001900.77315128
54Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.77177892
55Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.72327471
56Autoimmune thyroid disease_Homo sapiens_hsa053200.71546798
57Fatty acid degradation_Homo sapiens_hsa000710.71392712
58Arachidonic acid metabolism_Homo sapiens_hsa005900.71230549
59Pertussis_Homo sapiens_hsa051330.71123338
60Viral myocarditis_Homo sapiens_hsa054160.68492373
61Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.67862151
62Fatty acid elongation_Homo sapiens_hsa000620.67008284
63Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.66889469
64Tuberculosis_Homo sapiens_hsa051520.66310636
65Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.65971107
66Complement and coagulation cascades_Homo sapiens_hsa046100.65435539
67T cell receptor signaling pathway_Homo sapiens_hsa046600.65427931
68Histidine metabolism_Homo sapiens_hsa003400.65146682
69Ether lipid metabolism_Homo sapiens_hsa005650.63979287
70Parkinsons disease_Homo sapiens_hsa050120.62574511
71Jak-STAT signaling pathway_Homo sapiens_hsa046300.60927589
72Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.60765362
73p53 signaling pathway_Homo sapiens_hsa041150.60717765
74Toll-like receptor signaling pathway_Homo sapiens_hsa046200.59139629
75TNF signaling pathway_Homo sapiens_hsa046680.57927761
76Amphetamine addiction_Homo sapiens_hsa050310.57212590
77Graft-versus-host disease_Homo sapiens_hsa053320.56748370
78Osteoclast differentiation_Homo sapiens_hsa043800.56399470
79Nucleotide excision repair_Homo sapiens_hsa034200.55586912
80Apoptosis_Homo sapiens_hsa042100.54623549
81Fatty acid metabolism_Homo sapiens_hsa012120.54542183
82Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.54219240
83Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.53330276
84Vibrio cholerae infection_Homo sapiens_hsa051100.52725051
85Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.52194870
86Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51880548
87Peroxisome_Homo sapiens_hsa041460.51713065
88African trypanosomiasis_Homo sapiens_hsa051430.50644315
89HTLV-I infection_Homo sapiens_hsa051660.50425678
90beta-Alanine metabolism_Homo sapiens_hsa004100.49465675
91Biosynthesis of amino acids_Homo sapiens_hsa012300.49341446
92Long-term potentiation_Homo sapiens_hsa047200.48124570
93Ribosome_Homo sapiens_hsa030100.48022767
94Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.45391110
95Viral carcinogenesis_Homo sapiens_hsa052030.44698692
96SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41828436
97GABAergic synapse_Homo sapiens_hsa047270.40866553
98Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.40820332
99Circadian entrainment_Homo sapiens_hsa047130.40760024
100Hematopoietic cell lineage_Homo sapiens_hsa046400.40237836
101Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.39636352
102Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.39481847
103RNA degradation_Homo sapiens_hsa030180.38509959
104Glutamatergic synapse_Homo sapiens_hsa047240.35694133
105Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.34725388
106Chemokine signaling pathway_Homo sapiens_hsa040620.34342485
107Tyrosine metabolism_Homo sapiens_hsa003500.33790014
108Hepatitis B_Homo sapiens_hsa051610.33081551
109Cysteine and methionine metabolism_Homo sapiens_hsa002700.32506157
110Platelet activation_Homo sapiens_hsa046110.32270258
111Leukocyte transendothelial migration_Homo sapiens_hsa046700.32076202
112Propanoate metabolism_Homo sapiens_hsa006400.32064686
113Renin secretion_Homo sapiens_hsa049240.31877048
114Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.31775773
115Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.31144020
116Phagosome_Homo sapiens_hsa041450.29432310
117Pentose and glucuronate interconversions_Homo sapiens_hsa000400.28963081
118Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.28413366
119Fanconi anemia pathway_Homo sapiens_hsa034600.28093926
120Carbon metabolism_Homo sapiens_hsa012000.27484644
121Caffeine metabolism_Homo sapiens_hsa002320.27085336
122Thyroid hormone synthesis_Homo sapiens_hsa049180.27057329
123Bile secretion_Homo sapiens_hsa049760.26596510
124Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.26522401
125Pyrimidine metabolism_Homo sapiens_hsa002400.25651685
126Legionellosis_Homo sapiens_hsa051340.24969747
127Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.24395518
128Cyanoamino acid metabolism_Homo sapiens_hsa004600.23615939
129Aldosterone synthesis and secretion_Homo sapiens_hsa049250.22880497
130Butanoate metabolism_Homo sapiens_hsa006500.21703132
131Transcriptional misregulation in cancer_Homo sapiens_hsa052020.21572939
132Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.21526705
133One carbon pool by folate_Homo sapiens_hsa006700.20807002
134Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.19612831
135NOD-like receptor signaling pathway_Homo sapiens_hsa046210.14331588
136Hepatitis C_Homo sapiens_hsa051600.14195521
137Amoebiasis_Homo sapiens_hsa051460.12617802
138Ovarian steroidogenesis_Homo sapiens_hsa049130.11326705
139Purine metabolism_Homo sapiens_hsa002300.11040704
140RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.09166165
141Alcoholism_Homo sapiens_hsa050340.08105807

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