Rank | Gene Set | Z-score |
---|---|---|
1 | leukocyte migration involved in inflammatory response (GO:0002523) | 6.04512140 |
2 | negative regulation of cell killing (GO:0031342) | 5.18676867 |
3 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.18676867 |
4 | detection of bacterium (GO:0016045) | 5.03284602 |
5 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 4.97895748 |
6 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.97864080 |
7 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 4.92492690 |
8 | detection of other organism (GO:0098543) | 4.88997131 |
9 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.85729880 |
10 | positive regulation of respiratory burst (GO:0060267) | 4.84545253 |
11 | negative regulation of interleukin-12 production (GO:0032695) | 4.83837223 |
12 | leukocyte aggregation (GO:0070486) | 4.83495529 |
13 | positive regulation of antigen processing and presentation (GO:0002579) | 4.49924582 |
14 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.43097896 |
15 | cellular extravasation (GO:0045123) | 4.37626358 |
16 | response to peptidoglycan (GO:0032494) | 4.36887474 |
17 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.22364029 |
18 | response to host immune response (GO:0052572) | 4.22364029 |
19 | neutrophil activation involved in immune response (GO:0002283) | 4.20816748 |
20 | microglial cell activation (GO:0001774) | 4.19464478 |
21 | detection of external biotic stimulus (GO:0098581) | 4.17121480 |
22 | detection of molecule of bacterial origin (GO:0032490) | 3.97308221 |
23 | macrophage activation involved in immune response (GO:0002281) | 3.93546956 |
24 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.88211479 |
25 | response to host (GO:0075136) | 3.88211479 |
26 | response to host defenses (GO:0052200) | 3.88211479 |
27 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.80670544 |
28 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.80670544 |
29 | regulation of antigen processing and presentation (GO:0002577) | 3.80250688 |
30 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.78800796 |
31 | positive regulation of granulocyte chemotaxis (GO:0071624) | 3.78539299 |
32 | response to muramyl dipeptide (GO:0032495) | 3.67850837 |
33 | regulation of gamma-delta T cell activation (GO:0046643) | 3.64979869 |
34 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.64284747 |
35 | positive regulation of neutrophil chemotaxis (GO:0090023) | 3.63720725 |
36 | positive regulation of neutrophil migration (GO:1902624) | 3.63720725 |
37 | germinal center formation (GO:0002467) | 3.63320367 |
38 | NIK/NF-kappaB signaling (GO:0038061) | 3.60805866 |
39 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.59679724 |
40 | response to interleukin-15 (GO:0070672) | 3.59423449 |
41 | detection of biotic stimulus (GO:0009595) | 3.56450139 |
42 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.53722675 |
43 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.47388297 |
44 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.47191685 |
45 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.45413392 |
46 | cellular response to type I interferon (GO:0071357) | 3.43047903 |
47 | type I interferon signaling pathway (GO:0060337) | 3.43047903 |
48 | regulation of hypersensitivity (GO:0002883) | 3.43045571 |
49 | response to type I interferon (GO:0034340) | 3.39786570 |
50 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.38912479 |
51 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.32333975 |
52 | defense response to protozoan (GO:0042832) | 3.30687115 |
53 | neutrophil activation (GO:0042119) | 3.29216770 |
54 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.28787881 |
55 | negative regulation of T cell mediated immunity (GO:0002710) | 3.25383421 |
56 | respiratory burst (GO:0045730) | 3.24260656 |
57 | cellular response to interleukin-15 (GO:0071350) | 3.22283269 |
58 | granulocyte activation (GO:0036230) | 3.21165168 |
59 | regulation of mast cell activation (GO:0033003) | 3.21018797 |
60 | T-helper 1 type immune response (GO:0042088) | 3.18992569 |
61 | regulation of leukocyte degranulation (GO:0043300) | 3.17216331 |
62 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.17124196 |
63 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.17124196 |
64 | regulation of neutrophil migration (GO:1902622) | 3.16997482 |
65 | regulation of neutrophil chemotaxis (GO:0090022) | 3.16997482 |
66 | myeloid dendritic cell differentiation (GO:0043011) | 3.16095806 |
67 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.15680747 |
68 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.15614479 |
69 | myeloid leukocyte mediated immunity (GO:0002444) | 3.15517075 |
70 | immunoglobulin mediated immune response (GO:0016064) | 3.14955323 |
71 | positive regulation of macrophage activation (GO:0043032) | 3.13244790 |
72 | positive regulation of mast cell activation (GO:0033005) | 3.12134699 |
73 | neutrophil mediated immunity (GO:0002446) | 3.10812597 |
74 | B cell mediated immunity (GO:0019724) | 3.08825256 |
75 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.07858184 |
76 | positive regulation of interferon-alpha production (GO:0032727) | 3.07361399 |
77 | myeloid leukocyte activation (GO:0002274) | 3.06233289 |
78 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.04284605 |
79 | regulation of granulocyte chemotaxis (GO:0071622) | 3.04203023 |
80 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.00906627 |
81 | positive regulation of mast cell degranulation (GO:0043306) | 3.00906627 |
82 | regulation of tolerance induction (GO:0002643) | 2.99671565 |
83 | myeloid cell activation involved in immune response (GO:0002275) | 2.99520027 |
84 | myeloid dendritic cell activation (GO:0001773) | 2.98144526 |
85 | response to protozoan (GO:0001562) | 2.97795033 |
86 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.97397573 |
87 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.96598777 |
88 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.94606799 |
89 | regulation of interferon-alpha production (GO:0032647) | 2.92874182 |
90 | negative regulation of interleukin-6 production (GO:0032715) | 2.92396783 |
91 | leukocyte degranulation (GO:0043299) | 2.91595736 |
92 | negative regulation of growth of symbiont in host (GO:0044130) | 2.91282897 |
93 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 2.91282897 |
94 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 2.91282897 |
95 | regulation of growth of symbiont in host (GO:0044126) | 2.91282897 |
96 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.90562649 |
97 | hydrogen peroxide biosynthetic process (GO:0050665) | 2.89666781 |
98 | superoxide anion generation (GO:0042554) | 2.88283918 |
99 | regulation of mast cell degranulation (GO:0043304) | 2.87828085 |
100 | regulation of monocyte chemotaxis (GO:0090025) | 2.87491115 |
101 | regulation of podosome assembly (GO:0071801) | 2.87276322 |
102 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.86414984 |
103 | T-helper cell differentiation (GO:0042093) | 2.86414984 |
104 | regulation of macrophage cytokine production (GO:0010935) | 2.85810786 |
105 | dendritic cell migration (GO:0036336) | 2.85121242 |
106 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.84398881 |
107 | defense response to fungus (GO:0050832) | 2.84155432 |
108 | regulation of T cell tolerance induction (GO:0002664) | 2.83284561 |
109 | regulation of toll-like receptor 4 signaling pathway (GO:0034143) | 2.82652969 |
110 | leukotriene metabolic process (GO:0006691) | 2.81671233 |
111 | neutrophil chemotaxis (GO:0030593) | 2.81313089 |
112 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.81236222 |
113 | granulocyte chemotaxis (GO:0071621) | 2.81214151 |
114 | sequestering of metal ion (GO:0051238) | 2.81148872 |
115 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.80665641 |
116 | lipoxygenase pathway (GO:0019372) | 2.79208794 |
117 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.79074970 |
118 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.79074970 |
119 | modulation by symbiont of host immune response (GO:0052553) | 2.79074970 |
120 | positive regulation by symbiont of host defense response (GO:0052509) | 2.79074970 |
121 | modulation by symbiont of host defense response (GO:0052031) | 2.79074970 |
122 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.79074970 |
123 | negative regulation of interleukin-17 production (GO:0032700) | 2.78867888 |
124 | dendritic cell chemotaxis (GO:0002407) | 2.78382385 |
125 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.77601062 |
126 | response to fungus (GO:0009620) | 2.77562268 |
127 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.76515998 |
128 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.74124972 |
129 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.73322934 |
130 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.72921840 |
131 | neutrophil migration (GO:1990266) | 2.72866599 |
132 | macrophage activation (GO:0042116) | 2.72805132 |
133 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.71390706 |
134 | growth hormone receptor signaling pathway (GO:0060396) | 2.71054244 |
135 | T cell activation involved in immune response (GO:0002286) | 2.70940945 |
136 | negative regulation of complement activation (GO:0045916) | 2.69699391 |
137 | regulation of activation of Janus kinase activity (GO:0010533) | 2.69694697 |
138 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.68888551 |
139 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.68830091 |
140 | positive regulation of interleukin-12 production (GO:0032735) | 2.68598310 |
141 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.67844792 |
142 | tolerance induction (GO:0002507) | 2.66565032 |
143 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.65508794 |
144 | positive regulation of tumor necrosis factor production (GO:0032760) | 2.64146988 |
145 | positive regulation of humoral immune response (GO:0002922) | 2.63592067 |
146 | leukocyte cell-cell adhesion (GO:0007159) | 2.63243408 |
147 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.63084834 |
148 | natural killer cell activation involved in immune response (GO:0002323) | 2.63052033 |
149 | negative regulation of bone resorption (GO:0045779) | 2.62891276 |
150 | regulation of respiratory burst (GO:0060263) | 2.62786690 |
151 | defense response to Gram-positive bacterium (GO:0050830) | 2.62001943 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 6.08376922 |
2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.83308217 |
3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.46320119 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.34991583 |
5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.02276414 |
6 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.83260306 |
7 | * STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.22730372 |
8 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.21121324 |
9 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.05307039 |
10 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.00370183 |
11 | * MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.98366046 |
12 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.96389906 |
13 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.86948149 |
14 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.73581956 |
15 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.72070035 |
16 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.54343329 |
17 | * Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.53530073 |
18 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.39681106 |
19 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.27808271 |
20 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.23100944 |
21 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.15134004 |
22 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.07782436 |
23 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.06558030 |
24 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.92952201 |
25 | MYB_26560356_Chip-Seq_TH2_Human | 1.86353281 |
26 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.78778777 |
27 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.77189542 |
28 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.75503189 |
29 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.74542016 |
30 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.72353056 |
31 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.71759843 |
32 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.71721757 |
33 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.69116419 |
34 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.67847398 |
35 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.66783655 |
36 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.62742997 |
37 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.61309853 |
38 | MAF_26560356_Chip-Seq_TH1_Human | 1.59556396 |
39 | * VDR_24763502_ChIP-Seq_THP-1_Human | 1.52947890 |
40 | GATA1_22025678_ChIP-Seq_K562_Human | 1.50415994 |
41 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.46357821 |
42 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.46113686 |
43 | * PU_27001747_Chip-Seq_BMDM_Mouse | 1.44636229 |
44 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.42544360 |
45 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.42178135 |
46 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.39224998 |
47 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.38668257 |
48 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.38512118 |
49 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.37850338 |
50 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.36910511 |
51 | SPI1_23127762_ChIP-Seq_K562_Human | 1.36020873 |
52 | MYC_22102868_ChIP-Seq_BL_Human | 1.35888879 |
53 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.34547577 |
54 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.32984533 |
55 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.32984533 |
56 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.31998547 |
57 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.30694969 |
58 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.28661233 |
59 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.27688594 |
60 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.25095656 |
61 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.24184556 |
62 | MYB_26560356_Chip-Seq_TH1_Human | 1.23577109 |
63 | GATA3_26560356_Chip-Seq_TH2_Human | 1.23524342 |
64 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.22125648 |
65 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.20532869 |
66 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.20179323 |
67 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.18531300 |
68 | * VDR_21846776_ChIP-Seq_THP-1_Human | 1.17501405 |
69 | * SOX2_20726797_ChIP-Seq_SW620_Human | 1.16517911 |
70 | * GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.15062190 |
71 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.14958882 |
72 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.12802187 |
73 | * SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.12682926 |
74 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.11899040 |
75 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.11586234 |
76 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.11327134 |
77 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.07809495 |
78 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.07289358 |
79 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.06278159 |
80 | CJUN_26792858_Chip-Seq_BT549_Human | 1.06057641 |
81 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.05651057 |
82 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.05379311 |
83 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.05078269 |
84 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.04301476 |
85 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.02625303 |
86 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.02283941 |
87 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.00972410 |
88 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.00707434 |
89 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.97769587 |
90 | * GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.97586897 |
91 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.97219718 |
92 | * UTX_26944678_Chip-Seq_JUKART_Human | 0.95555266 |
93 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.94858083 |
94 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.94818873 |
95 | GATA1_19941826_ChIP-Seq_K562_Human | 0.92855231 |
96 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.92091705 |
97 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.92033463 |
98 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.91544156 |
99 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.90704538 |
100 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.90520727 |
101 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.90074234 |
102 | * CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.89866317 |
103 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.89360198 |
104 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.88733886 |
105 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.87134556 |
106 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.85628662 |
107 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.85526778 |
108 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.85270508 |
109 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.84963285 |
110 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.84601265 |
111 | GATA2_19941826_ChIP-Seq_K562_Human | 0.84109897 |
112 | * NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.82882749 |
113 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82777969 |
114 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.82697851 |
115 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.82578851 |
116 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.82403620 |
117 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.82324830 |
118 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.81510741 |
119 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.78938780 |
120 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.78938780 |
121 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.77517564 |
122 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.77137441 |
123 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.76965969 |
124 | MAF_26560356_Chip-Seq_TH2_Human | 0.75953120 |
125 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.72921657 |
126 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.72658527 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 4.21810844 |
2 | MP0002254_reproductive_system_inflammat | 3.67580741 |
3 | MP0009785_altered_susceptibility_to | 3.41859291 |
4 | MP0003436_decreased_susceptibility_to | 3.37197167 |
5 | MP0002148_abnormal_hypersensitivity_rea | 3.22886475 |
6 | MP0000685_abnormal_immune_system | 3.13913124 |
7 | MP0003303_peritoneal_inflammation | 3.01246790 |
8 | MP0002419_abnormal_innate_immunity | 2.79954816 |
9 | MP0004510_myositis | 2.75981893 |
10 | MP0005671_abnormal_response_to | 2.69020464 |
11 | MP0005387_immune_system_phenotype | 2.68814486 |
12 | MP0001790_abnormal_immune_system | 2.68814486 |
13 | MP0005025_abnormal_response_to | 2.64869780 |
14 | MP0005000_abnormal_immune_tolerance | 2.61749478 |
15 | MP0001853_heart_inflammation | 2.49798531 |
16 | MP0003724_increased_susceptibility_to | 2.47322586 |
17 | MP0001800_abnormal_humoral_immune | 2.35676962 |
18 | MP0002452_abnormal_antigen_presenting | 2.23194601 |
19 | MP0004947_skin_inflammation | 2.20990795 |
20 | MP0002723_abnormal_immune_serum | 2.14086948 |
21 | MP0002138_abnormal_hepatobiliary_system | 2.09813971 |
22 | MP0001819_abnormal_immune_cell | 2.02833219 |
23 | MP0002420_abnormal_adaptive_immunity | 2.01615767 |
24 | MP0001533_abnormal_skeleton_physiology | 2.01351113 |
25 | MP0002405_respiratory_system_inflammati | 1.98816064 |
26 | MP0008260_abnormal_autophagy | 1.96591937 |
27 | MP0003453_abnormal_keratinocyte_physiol | 1.95792870 |
28 | MP0010234_abnormal_vibrissa_follicle | 1.90159377 |
29 | MP0002796_impaired_skin_barrier | 1.85265328 |
30 | MP0002877_abnormal_melanocyte_morpholog | 1.85044577 |
31 | MP0005451_abnormal_body_composition | 1.84429071 |
32 | MP0009278_abnormal_bone_marrow | 1.81505655 |
33 | MP0001845_abnormal_inflammatory_respons | 1.79586188 |
34 | MP0005310_abnormal_salivary_gland | 1.79003598 |
35 | MP0006082_CNS_inflammation | 1.76094287 |
36 | MP0003448_altered_tumor_morphology | 1.75400023 |
37 | MP0003172_abnormal_lysosome_physiology | 1.73346467 |
38 | MP0004381_abnormal_hair_follicle | 1.67937910 |
39 | MP0009764_decreased_sensitivity_to | 1.67286824 |
40 | MP0002132_abnormal_respiratory_system | 1.64678538 |
41 | MP0001542_abnormal_bone_strength | 1.60114462 |
42 | MP0000858_altered_metastatic_potential | 1.59786495 |
43 | MP0010155_abnormal_intestine_physiology | 1.59093412 |
44 | MP0000383_abnormal_hair_follicle | 1.57467395 |
45 | MP0005464_abnormal_platelet_physiology | 1.57356032 |
46 | MP0001851_eye_inflammation | 1.50876669 |
47 | MP0003300_gastrointestinal_ulcer | 1.48277294 |
48 | MP0000604_amyloidosis | 1.46146622 |
49 | MP0003941_abnormal_skin_development | 1.46142069 |
50 | MP0002060_abnormal_skin_morphology | 1.42582423 |
51 | MP0005275_abnormal_skin_tensile | 1.42192568 |
52 | MP0010678_abnormal_skin_adnexa | 1.38221188 |
53 | MP0003566_abnormal_cell_adhesion | 1.36712721 |
54 | MP0008004_abnormal_stomach_pH | 1.35928682 |
55 | MP0000716_abnormal_immune_system | 1.35751062 |
56 | MP0001216_abnormal_epidermal_layer | 1.34630624 |
57 | MP0002277_abnormal_respiratory_mucosa | 1.33657960 |
58 | MP0000343_altered_response_to | 1.33582115 |
59 | MP0002998_abnormal_bone_remodeling | 1.33572562 |
60 | MP0010352_gastrointestinal_tract_polyps | 1.32788862 |
61 | MP0003828_pulmonary_edema | 1.29098529 |
62 | MP0002398_abnormal_bone_marrow | 1.26131828 |
63 | MP0008469_abnormal_protein_level | 1.21753983 |
64 | MP0002006_tumorigenesis | 1.21007452 |
65 | MP0005397_hematopoietic_system_phenotyp | 1.18989802 |
66 | MP0001545_abnormal_hematopoietic_system | 1.18989802 |
67 | MP0003806_abnormal_nucleotide_metabolis | 1.16741704 |
68 | MP0002166_altered_tumor_susceptibility | 1.14607927 |
69 | MP0009333_abnormal_splenocyte_physiolog | 1.13916064 |
70 | MP0000465_gastrointestinal_hemorrhage | 1.13535422 |
71 | MP0003191_abnormal_cellular_cholesterol | 1.13311305 |
72 | MP0005023_abnormal_wound_healing | 1.11143799 |
73 | MP0005166_decreased_susceptibility_to | 1.10962014 |
74 | MP0005390_skeleton_phenotype | 1.09580734 |
75 | MP0001348_abnormal_lacrimal_gland | 1.08962773 |
76 | MP0002396_abnormal_hematopoietic_system | 1.08763393 |
77 | MP0005164_abnormal_response_to | 1.08086442 |
78 | MP0003045_fibrosis | 1.07712939 |
79 | MP0003075_altered_response_to | 1.07430964 |
80 | MP0003763_abnormal_thymus_physiology | 1.07243988 |
81 | MP0002429_abnormal_blood_cell | 1.05553780 |
82 | MP0008438_abnormal_cutaneous_collagen | 1.03418392 |
83 | MP0002933_joint_inflammation | 1.01939000 |
84 | MP0003690_abnormal_glial_cell | 0.99802656 |
85 | MP0002722_abnormal_immune_system | 0.99136565 |
86 | MP0003183_abnormal_peptide_metabolism | 0.98461565 |
87 | MP0003656_abnormal_erythrocyte_physiolo | 0.95969593 |
88 | MP0009840_abnormal_foam_cell | 0.95032928 |
89 | MP0005058_abnormal_lysosome_morphology | 0.94383678 |
90 | MP0004782_abnormal_surfactant_physiolog | 0.94150786 |
91 | MP0005501_abnormal_skin_physiology | 0.93635272 |
92 | MP0000703_abnormal_thymus_morphology | 0.93319242 |
93 | MP0004883_abnormal_blood_vessel | 0.92688824 |
94 | MP0009763_increased_sensitivity_to | 0.90681018 |
95 | MP0000681_abnormal_thyroid_gland | 0.87063311 |
96 | MP0003866_abnormal_defecation | 0.86318215 |
97 | MP0003279_aneurysm | 0.86277594 |
98 | MP0009931_abnormal_skin_appearance | 0.85557309 |
99 | MP0000689_abnormal_spleen_morphology | 0.83703787 |
100 | MP0001663_abnormal_digestive_system | 0.83582646 |
101 | MP0001191_abnormal_skin_condition | 0.82460864 |
102 | MP0010771_integument_phenotype | 0.82389666 |
103 | MP0001346_abnormal_lacrimal_gland | 0.79269220 |
104 | MP0000569_abnormal_digit_pigmentation | 0.78333555 |
105 | MP0001873_stomach_inflammation | 0.78291735 |
106 | MP0005167_abnormal_blood-brain_barrier | 0.77858040 |
107 | MP0000767_abnormal_smooth_muscle | 0.77042543 |
108 | MP0009765_abnormal_xenobiotic_induced | 0.76681504 |
109 | MP0001958_emphysema | 0.74927161 |
110 | MP0001243_abnormal_dermal_layer | 0.74337674 |
111 | MP0005076_abnormal_cell_differentiation | 0.72902651 |
112 | MP0000377_abnormal_hair_follicle | 0.72517901 |
113 | MP0002332_abnormal_exercise_endurance | 0.71834854 |
114 | MP0001881_abnormal_mammary_gland | 0.71762143 |
115 | MP0000249_abnormal_blood_vessel | 0.71744831 |
116 | MP0003795_abnormal_bone_structure | 0.70454510 |
117 | MP0003638_abnormal_response/metabolism_ | 0.69547325 |
118 | MP0005174_abnormal_tail_pigmentation | 0.69214368 |
119 | MP0008874_decreased_physiological_sensi | 0.67086665 |
120 | MP0003221_abnormal_cardiomyocyte_apopto | 0.65619871 |
121 | MP0005319_abnormal_enzyme/_coenzyme | 0.62135533 |
122 | MP0000015_abnormal_ear_pigmentation | 0.61065401 |
123 | MP0003091_abnormal_cell_migration | 0.59778329 |
124 | MP0004808_abnormal_hematopoietic_stem | 0.58485124 |
125 | MP0000920_abnormal_myelination | 0.56499146 |
126 | MP0004264_abnormal_extraembryonic_tissu | 0.53376142 |
127 | MP0000609_abnormal_liver_physiology | 0.52228249 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Eczematoid dermatitis (HP:0000976) | 7.01242681 |
2 | Recurrent abscess formation (HP:0002722) | 5.20957810 |
3 | Myositis (HP:0100614) | 5.00485720 |
4 | Recurrent bacterial skin infections (HP:0005406) | 4.91140329 |
5 | Orchitis (HP:0100796) | 4.68102988 |
6 | Optic neuritis (HP:0100653) | 4.32372523 |
7 | Retrobulbar optic neuritis (HP:0100654) | 4.32372523 |
8 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.08714431 |
9 | Spondylolisthesis (HP:0003302) | 4.03147541 |
10 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 3.94229039 |
11 | Osteolytic defects of the hand bones (HP:0009699) | 3.94229039 |
12 | Abnormality of macrophages (HP:0004311) | 3.91488594 |
13 | Absent frontal sinuses (HP:0002688) | 3.85055119 |
14 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.77342452 |
15 | Persistence of primary teeth (HP:0006335) | 3.70208184 |
16 | Chronic obstructive pulmonary disease (HP:0006510) | 3.66827344 |
17 | Obstructive lung disease (HP:0006536) | 3.66827344 |
18 | Mediastinal lymphadenopathy (HP:0100721) | 3.62583735 |
19 | Systemic lupus erythematosus (HP:0002725) | 3.52295606 |
20 | Recurrent fungal infections (HP:0002841) | 3.42846200 |
21 | Abnormality of proline metabolism (HP:0010907) | 3.32020784 |
22 | Hydroxyprolinuria (HP:0003080) | 3.32020784 |
23 | Vacuolated lymphocytes (HP:0001922) | 3.27567254 |
24 | Keratoconjunctivitis sicca (HP:0001097) | 3.26574721 |
25 | Chronic otitis media (HP:0000389) | 3.18689857 |
26 | Recurrent skin infections (HP:0001581) | 3.18224300 |
27 | Gastrointestinal infarctions (HP:0005244) | 3.14807518 |
28 | Keratoconjunctivitis (HP:0001096) | 3.09754143 |
29 | Gingivitis (HP:0000230) | 3.05286358 |
30 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 3.03612023 |
31 | Increased IgE level (HP:0003212) | 3.02245847 |
32 | Chest pain (HP:0100749) | 2.96850881 |
33 | Amyloidosis (HP:0011034) | 2.95705982 |
34 | Episodic fever (HP:0001954) | 2.95570761 |
35 | Stomatitis (HP:0010280) | 2.94193258 |
36 | Prolonged bleeding time (HP:0003010) | 2.93199169 |
37 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 2.90776526 |
38 | Thick nail (HP:0001805) | 2.89839681 |
39 | Vasculitis (HP:0002633) | 2.80615852 |
40 | Meningitis (HP:0001287) | 2.79161224 |
41 | Osteomyelitis (HP:0002754) | 2.78790607 |
42 | Hypochromic microcytic anemia (HP:0004840) | 2.77245008 |
43 | Cellulitis (HP:0100658) | 2.74178301 |
44 | Abnormality of the frontal sinuses (HP:0002687) | 2.69104394 |
45 | Pustule (HP:0200039) | 2.67214051 |
46 | Epistaxis (HP:0000421) | 2.66973694 |
47 | Hemoptysis (HP:0002105) | 2.65130569 |
48 | Arterial thrombosis (HP:0004420) | 2.63125317 |
49 | Pulmonary infiltrates (HP:0002113) | 2.60764553 |
50 | Interstitial pulmonary disease (HP:0006530) | 2.60397579 |
51 | T lymphocytopenia (HP:0005403) | 2.56447350 |
52 | Hypochromic anemia (HP:0001931) | 2.56379484 |
53 | Gangrene (HP:0100758) | 2.55966154 |
54 | Abnormality of T cell number (HP:0011839) | 2.53699039 |
55 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.49074364 |
56 | Recurrent cutaneous fungal infections (HP:0011370) | 2.49074364 |
57 | Abnormality of glycolipid metabolism (HP:0010969) | 2.47352778 |
58 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.47352778 |
59 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.47352778 |
60 | Urticaria (HP:0001025) | 2.45102234 |
61 | Plantar hyperkeratosis (HP:0007556) | 2.43246175 |
62 | Inflammation of the large intestine (HP:0002037) | 2.40040449 |
63 | Increased IgM level (HP:0003496) | 2.37209976 |
64 | Premature loss of primary teeth (HP:0006323) | 2.36668953 |
65 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.32362438 |
66 | Mucopolysacchariduria (HP:0008155) | 2.32362438 |
67 | Petechiae (HP:0000967) | 2.31315432 |
68 | Leukocytosis (HP:0001974) | 2.29601389 |
69 | Abnormality of the peritoneum (HP:0002585) | 2.28593440 |
70 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.27726956 |
71 | Peritonitis (HP:0002586) | 2.27649547 |
72 | Gastrointestinal inflammation (HP:0004386) | 2.26873893 |
73 | Recurrent viral infections (HP:0004429) | 2.26800559 |
74 | Increased cerebral lipofuscin (HP:0011813) | 2.26135726 |
75 | Gingival bleeding (HP:0000225) | 2.25516048 |
76 | Spontaneous hematomas (HP:0007420) | 2.24624699 |
77 | Purpura (HP:0000979) | 2.22327987 |
78 | Ridged nail (HP:0001807) | 2.20202016 |
79 | Xerostomia (HP:0000217) | 2.19324922 |
80 | Abnormality of the endocardium (HP:0004306) | 2.18807850 |
81 | Keratitis (HP:0000491) | 2.18493549 |
82 | Recurrent bronchitis (HP:0002837) | 2.18205877 |
83 | Skin ulcer (HP:0200042) | 2.17956682 |
84 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.16846596 |
85 | Loss of speech (HP:0002371) | 2.15961440 |
86 | Periodontitis (HP:0000704) | 2.13737897 |
87 | Abnormality of T cells (HP:0002843) | 2.13721337 |
88 | Milia (HP:0001056) | 2.12697317 |
89 | Palmoplantar hyperkeratosis (HP:0000972) | 2.12624383 |
90 | Acne (HP:0001061) | 2.12277924 |
91 | Glomerulopathy (HP:0100820) | 2.11069300 |
92 | Encephalitis (HP:0002383) | 2.10660386 |
93 | Granulocytopenia (HP:0001913) | 2.09924206 |
94 | Thickened calvaria (HP:0002684) | 2.09680980 |
95 | Cervical subluxation (HP:0003308) | 2.09568152 |
96 | Dysostosis multiplex (HP:0000943) | 2.09345399 |
97 | Increased serum ferritin (HP:0003281) | 2.08896192 |
98 | Delayed closure of the anterior fontanelle (HP:0001476) | 2.07844120 |
99 | Eosinophilia (HP:0001880) | 2.07278490 |
100 | Joint swelling (HP:0001386) | 2.06791307 |
101 | Hepatosplenomegaly (HP:0001433) | 2.06622378 |
102 | Abnormal hemoglobin (HP:0011902) | 2.05272188 |
103 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.04122607 |
104 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.04122607 |
105 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.04122607 |
106 | Cheilitis (HP:0100825) | 2.01657164 |
107 | Anorexia (HP:0002039) | 2.01645275 |
108 | Vertigo (HP:0002321) | 2.01465233 |
109 | Autoimmune thrombocytopenia (HP:0001973) | 2.00993510 |
110 | Disinhibition (HP:0000734) | 2.00474964 |
111 | Sepsis (HP:0100806) | 1.99666666 |
112 | IgM deficiency (HP:0002850) | 1.99208065 |
113 | Parakeratosis (HP:0001036) | 1.99201534 |
114 | Hematochezia (HP:0002573) | 1.99176715 |
115 | Nasal polyposis (HP:0100582) | 1.98909337 |
116 | Abnormality of the nasal mucosa (HP:0000433) | 1.98420730 |
117 | Erythema (HP:0010783) | 1.97993676 |
118 | Right ventricular cardiomyopathy (HP:0011663) | 1.97939944 |
119 | Microcytic anemia (HP:0001935) | 1.97053824 |
120 | Hypotrichosis (HP:0001006) | 1.97018701 |
121 | Palmar hyperkeratosis (HP:0010765) | 1.96459863 |
122 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.96213415 |
123 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.95834718 |
124 | Polyneuropathy (HP:0001271) | 1.95144828 |
125 | Distal lower limb muscle weakness (HP:0009053) | 1.95080649 |
126 | Abnormality of the pericardium (HP:0001697) | 1.94798063 |
127 | Autoimmune hemolytic anemia (HP:0001890) | 1.92990945 |
128 | Malnutrition (HP:0004395) | 1.91952140 |
129 | Abnormality of iron homeostasis (HP:0011031) | 1.91904654 |
130 | Alopecia of scalp (HP:0002293) | 1.91755380 |
131 | Slow saccadic eye movements (HP:0000514) | 1.91556983 |
132 | Hypergammaglobulinemia (HP:0010702) | 1.91394070 |
133 | Ulnar deviation of the wrist (HP:0003049) | 1.90220675 |
134 | Fragile nails (HP:0001808) | 1.88026021 |
135 | Recurrent pneumonia (HP:0006532) | 1.87281078 |
136 | Abnormality of the pleura (HP:0002103) | 1.87090739 |
137 | Onycholysis (HP:0001806) | 1.86066442 |
138 | Pulmonary embolism (HP:0002204) | 1.85833232 |
139 | Colitis (HP:0002583) | 1.85359319 |
140 | Abnormality of T cell physiology (HP:0011840) | 1.83679082 |
141 | Abnormal platelet volume (HP:0011876) | 1.83155570 |
142 | Skin rash (HP:0000988) | 1.82484066 |
143 | Thrombophlebitis (HP:0004418) | 1.76286245 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP3K14 | 4.36274449 |
2 | BLK | 4.03666199 |
3 | EPHB1 | 3.07807069 |
4 | IRAK4 | 2.97202697 |
5 | MAP4K1 | 2.67075756 |
6 | TYK2 | 2.51725395 |
7 | RIPK4 | 2.51004225 |
8 | TRPM7 | 2.47135855 |
9 | TBK1 | 2.39687820 |
10 | IRAK3 | 2.34947535 |
11 | MST4 | 2.19481143 |
12 | JAK3 | 2.12126297 |
13 | IKBKB | 2.11218423 |
14 | CSK | 2.10940554 |
15 | ERN1 | 2.08986661 |
16 | TXK | 2.08350821 |
17 | EPHA3 | 2.08190930 |
18 | TGFBR2 | 2.08103948 |
19 | IKBKE | 1.98549536 |
20 | ERBB3 | 1.98294134 |
21 | TNK2 | 1.80727037 |
22 | MAP3K13 | 1.77619531 |
23 | FGR | 1.66798205 |
24 | JAK1 | 1.64873221 |
25 | STK10 | 1.60396010 |
26 | PRPF4B | 1.54603455 |
27 | CHUK | 1.54185129 |
28 | BMPR2 | 1.50877494 |
29 | STK24 | 1.49137455 |
30 | BTK | 1.48751081 |
31 | KSR2 | 1.48451576 |
32 | HCK | 1.47184475 |
33 | IRAK2 | 1.46097612 |
34 | MAP3K3 | 1.46047671 |
35 | TEC | 1.42101621 |
36 | ZAP70 | 1.41393242 |
37 | MST1R | 1.36059858 |
38 | MAP3K6 | 1.32965219 |
39 | ITK | 1.29950792 |
40 | FGFR4 | 1.29090860 |
41 | CLK1 | 1.27851255 |
42 | SIK3 | 1.26887817 |
43 | MAP2K3 | 1.25055890 |
44 | MAP3K12 | 1.22392676 |
45 | PIM2 | 1.19341846 |
46 | LRRK2 | 1.17593832 |
47 | FGFR3 | 1.17159330 |
48 | JAK2 | 1.17090984 |
49 | YES1 | 1.15246423 |
50 | SYK | 1.14996494 |
51 | TAOK3 | 1.14086133 |
52 | KIT | 1.13607338 |
53 | MARK3 | 1.09683123 |
54 | MAPKAPK3 | 1.03738893 |
55 | TESK1 | 1.02664074 |
56 | TAOK2 | 1.01195016 |
57 | PIK3CG | 0.97675447 |
58 | PIM1 | 0.97186651 |
59 | IRAK1 | 0.92662746 |
60 | FES | 0.92372362 |
61 | PTK6 | 0.91957996 |
62 | LCK | 0.90891561 |
63 | MARK2 | 0.90778146 |
64 | NLK | 0.89749879 |
65 | LYN | 0.85450559 |
66 | CDC42BPA | 0.85233483 |
67 | MAP3K1 | 0.83518734 |
68 | EIF2AK2 | 0.82322767 |
69 | PRKD2 | 0.81469767 |
70 | MAPKAPK2 | 0.81373468 |
71 | LIMK1 | 0.80923496 |
72 | PDPK1 | 0.76720307 |
73 | MAP3K5 | 0.75522421 |
74 | MATK | 0.75384218 |
75 | CSF1R | 0.75117743 |
76 | RPS6KA4 | 0.68288523 |
77 | MAP2K4 | 0.66766280 |
78 | TTN | 0.66575741 |
79 | TESK2 | 0.62915807 |
80 | GRK6 | 0.62534369 |
81 | PTK2B | 0.60445388 |
82 | SGK3 | 0.58657409 |
83 | KSR1 | 0.58351572 |
84 | GRK7 | 0.57667274 |
85 | RIPK1 | 0.57303903 |
86 | DAPK2 | 0.56094640 |
87 | MAPKAPK5 | 0.55413875 |
88 | RAF1 | 0.53675115 |
89 | MAP2K6 | 0.53072188 |
90 | ABL1 | 0.52923228 |
91 | PRKCD | 0.52169999 |
92 | SIK2 | 0.51148493 |
93 | MAPK12 | 0.49223973 |
94 | ALK | 0.48771781 |
95 | MAP3K7 | 0.48633057 |
96 | PRKCQ | 0.48477284 |
97 | MAPK7 | 0.47627697 |
98 | DMPK | 0.47371906 |
99 | RET | 0.47044678 |
100 | TRIB3 | 0.45423478 |
101 | MOS | 0.44896761 |
102 | FRK | 0.44797706 |
103 | WNK1 | 0.44048454 |
104 | PTK2 | 0.42389339 |
105 | STK3 | 0.40808772 |
106 | STK11 | 0.40231334 |
107 | STK38 | 0.39567939 |
108 | MAPK4 | 0.39279676 |
109 | PRKG2 | 0.39117808 |
110 | CDK19 | 0.38197016 |
111 | MAP3K11 | 0.37714779 |
112 | SIK1 | 0.36508100 |
113 | FYN | 0.36070043 |
114 | CDK6 | 0.35922914 |
115 | DYRK1B | 0.35900463 |
116 | MYLK | 0.35398240 |
117 | PBK | 0.34640090 |
118 | SGK2 | 0.34578848 |
119 | SMG1 | 0.34438013 |
120 | ACVR1B | 0.33050288 |
121 | RPS6KA6 | 0.29511960 |
122 | IGF1R | 0.28907457 |
123 | EGFR | 0.28405302 |
124 | PDK1 | 0.27629723 |
125 | PAK4 | 0.26859128 |
126 | KDR | 0.24474815 |
127 | MAP3K2 | 0.24212442 |
128 | BMX | 0.24042170 |
129 | FER | 0.23848282 |
130 | NEK9 | 0.22686236 |
131 | HIPK2 | 0.22291089 |
132 | RPS6KL1 | 0.22202669 |
133 | RPS6KC1 | 0.22202669 |
134 | TAOK1 | 0.22060021 |
135 | GSK3A | 0.21461168 |
136 | RPS6KA1 | 0.20990460 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Asthma_Homo sapiens_hsa05310 | 2.98904793 |
2 | Leishmaniasis_Homo sapiens_hsa05140 | 2.98847532 |
3 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.75989806 |
4 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.68490141 |
5 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.54075409 |
6 | Allograft rejection_Homo sapiens_hsa05330 | 2.53732516 |
7 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.53545242 |
8 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.30085243 |
9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.19732063 |
10 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.02824817 |
11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.99455683 |
12 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.98856004 |
13 | Pertussis_Homo sapiens_hsa05133 | 1.98197387 |
14 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.86116238 |
15 | Tuberculosis_Homo sapiens_hsa05152 | 1.85555237 |
16 | Legionellosis_Homo sapiens_hsa05134 | 1.78288542 |
17 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.77525808 |
18 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.76887738 |
19 | * Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.75299584 |
20 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.74536083 |
21 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.73238682 |
22 | * Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.70527110 |
23 | Measles_Homo sapiens_hsa05162 | 1.69910189 |
24 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.62015678 |
25 | Salmonella infection_Homo sapiens_hsa05132 | 1.54164453 |
26 | Apoptosis_Homo sapiens_hsa04210 | 1.46014882 |
27 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.45024982 |
28 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.44332053 |
29 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.44273202 |
30 | Lysosome_Homo sapiens_hsa04142 | 1.44131589 |
31 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.42288204 |
32 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.41547003 |
33 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.36619238 |
34 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.34605620 |
35 | Shigellosis_Homo sapiens_hsa05131 | 1.33863371 |
36 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.31123929 |
37 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.27250944 |
38 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.26029333 |
39 | Malaria_Homo sapiens_hsa05144 | 1.25413251 |
40 | Influenza A_Homo sapiens_hsa05164 | 1.25137409 |
41 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.22744777 |
42 | Phagosome_Homo sapiens_hsa04145 | 1.18377136 |
43 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.18185958 |
44 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.17712059 |
45 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.15794988 |
46 | Histidine metabolism_Homo sapiens_hsa00340 | 1.11050155 |
47 | Other glycan degradation_Homo sapiens_hsa00511 | 1.10947538 |
48 | Viral myocarditis_Homo sapiens_hsa05416 | 1.09059684 |
49 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.06162384 |
50 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.05311982 |
51 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.03736907 |
52 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.97086790 |
53 | Hepatitis B_Homo sapiens_hsa05161 | 0.95444822 |
54 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.91385924 |
55 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.90804998 |
56 | * Amoebiasis_Homo sapiens_hsa05146 | 0.87962240 |
57 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.87539237 |
58 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.84914488 |
59 | Hepatitis C_Homo sapiens_hsa05160 | 0.84102575 |
60 | Platelet activation_Homo sapiens_hsa04611 | 0.80271970 |
61 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.79196599 |
62 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.79186760 |
63 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.75053903 |
64 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.74232571 |
65 | Endocytosis_Homo sapiens_hsa04144 | 0.72415070 |
66 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.71190786 |
67 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.71126146 |
68 | * Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.69542542 |
69 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.65334885 |
70 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.64787567 |
71 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.64218802 |
72 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.60494635 |
73 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.60360804 |
74 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.60293575 |
75 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.59572942 |
76 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.59127231 |
77 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.58667032 |
78 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.58199364 |
79 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.56828316 |
80 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.55934623 |
81 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.55772068 |
82 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.55461589 |
83 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.52749986 |
84 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.51822792 |
85 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.50008354 |
86 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.48783578 |
87 | Focal adhesion_Homo sapiens_hsa04510 | 0.47119401 |
88 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.47097595 |
89 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.46923480 |
90 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.46741003 |
91 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.46466803 |
92 | Bladder cancer_Homo sapiens_hsa05219 | 0.44155273 |
93 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.42725688 |
94 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.41283831 |
95 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.40871692 |
96 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.40829174 |
97 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.40510071 |
98 | Endometrial cancer_Homo sapiens_hsa05213 | 0.39454624 |
99 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.39324172 |
100 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.38580399 |
101 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.38139958 |
102 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.37014651 |
103 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.36940081 |
104 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.36929737 |
105 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.36417436 |
106 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.35310153 |
107 | Insulin resistance_Homo sapiens_hsa04931 | 0.34870743 |
108 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.34579849 |
109 | Galactose metabolism_Homo sapiens_hsa00052 | 0.33984649 |
110 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.33767976 |
111 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.32471836 |
112 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.31115979 |
113 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.30157494 |
114 | * MAPK signaling pathway_Homo sapiens_hsa04010 | 0.29790013 |
115 | Adherens junction_Homo sapiens_hsa04520 | 0.29409247 |
116 | * HTLV-I infection_Homo sapiens_hsa05166 | 0.29134066 |
117 | Pathways in cancer_Homo sapiens_hsa05200 | 0.28783290 |
118 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.28613295 |
119 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.28049059 |
120 | Prostate cancer_Homo sapiens_hsa05215 | 0.27151451 |
121 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.26720321 |
122 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.26477970 |
123 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.26447639 |
124 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.25084321 |