Rank | Gene Set | Z-score |
---|---|---|
1 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 6.79365281 |
2 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.27623342 |
3 | tolerance induction (GO:0002507) | 6.21530250 |
4 | negative T cell selection (GO:0043383) | 5.84352317 |
5 | regulation of vitamin D biosynthetic process (GO:0060556) | 5.77274679 |
6 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 5.73583960 |
7 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.58879307 |
8 | tyrosine phosphorylation of STAT protein (GO:0007260) | 5.54408765 |
9 | negative thymic T cell selection (GO:0045060) | 5.53560265 |
10 | positive regulation of natural killer cell differentiation (GO:0032825) | 5.46606930 |
11 | regulation of isotype switching to IgG isotypes (GO:0048302) | 5.40592293 |
12 | regulation of regulatory T cell differentiation (GO:0045589) | 5.24025857 |
13 | regulation of gamma-delta T cell activation (GO:0046643) | 5.02901549 |
14 | cytidine deamination (GO:0009972) | 4.86725190 |
15 | cytidine metabolic process (GO:0046087) | 4.86725190 |
16 | cytidine catabolic process (GO:0006216) | 4.86725190 |
17 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 4.85321809 |
18 | regulation of T-helper 1 cell differentiation (GO:0045625) | 4.78417045 |
19 | * response to interleukin-15 (GO:0070672) | 4.74410703 |
20 | regulation of immunoglobulin secretion (GO:0051023) | 4.70538692 |
21 | positive regulation of interleukin-2 production (GO:0032743) | 4.65113231 |
22 | regulation of vitamin metabolic process (GO:0030656) | 4.57680207 |
23 | positive regulation of interleukin-17 production (GO:0032740) | 4.55478262 |
24 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.49071659 |
25 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.48975174 |
26 | interferon-gamma production (GO:0032609) | 4.48508894 |
27 | positive regulation of T cell cytokine production (GO:0002726) | 4.46744561 |
28 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 4.44663732 |
29 | positive regulation of isotype switching (GO:0045830) | 4.43780685 |
30 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 4.41895475 |
31 | T cell selection (GO:0045058) | 4.41734268 |
32 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 4.40931653 |
33 | thymic T cell selection (GO:0045061) | 4.38458480 |
34 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.32879672 |
35 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.32879672 |
36 | positive T cell selection (GO:0043368) | 4.30842595 |
37 | positive regulation of defense response to virus by host (GO:0002230) | 4.30465302 |
38 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 4.27496288 |
39 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 4.21299517 |
40 | positive regulation of B cell mediated immunity (GO:0002714) | 4.21299517 |
41 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.18623500 |
42 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.18156210 |
43 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.18156210 |
44 | positive regulation of humoral immune response (GO:0002922) | 4.15650706 |
45 | positive thymic T cell selection (GO:0045059) | 4.15634951 |
46 | regulation of memory T cell differentiation (GO:0043380) | 4.15612326 |
47 | defense response to protozoan (GO:0042832) | 4.15315214 |
48 | regulation of podosome assembly (GO:0071801) | 4.14142643 |
49 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.10195508 |
50 | T cell costimulation (GO:0031295) | 4.05455096 |
51 | DNA deamination (GO:0045006) | 4.04202085 |
52 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 4.01256541 |
53 | lymphocyte costimulation (GO:0031294) | 3.99390500 |
54 | negative regulation of viral genome replication (GO:0045071) | 3.96778288 |
55 | regulation of chronic inflammatory response (GO:0002676) | 3.95985573 |
56 | negative regulation of interleukin-12 production (GO:0032695) | 3.94088019 |
57 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.92430658 |
58 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.92430658 |
59 | regulation of interleukin-2 production (GO:0032663) | 3.91019845 |
60 | positive regulation of tolerance induction (GO:0002645) | 3.90316615 |
61 | activated T cell proliferation (GO:0050798) | 3.89957732 |
62 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 3.85055362 |
63 | regulation of lymphocyte chemotaxis (GO:1901623) | 3.85002017 |
64 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.84409073 |
65 | myeloid dendritic cell differentiation (GO:0043011) | 3.80918572 |
66 | response to protozoan (GO:0001562) | 3.80594026 |
67 | cellular response to type I interferon (GO:0071357) | 3.80434721 |
68 | type I interferon signaling pathway (GO:0060337) | 3.80434721 |
69 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.79263583 |
70 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.78670346 |
71 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.78068275 |
72 | eosinophil chemotaxis (GO:0048245) | 3.76532754 |
73 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.75824465 |
74 | response to type I interferon (GO:0034340) | 3.75118247 |
75 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.74803656 |
76 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.73633742 |
77 | positive regulation of DNA recombination (GO:0045911) | 3.73054218 |
78 | T cell receptor signaling pathway (GO:0050852) | 3.71268618 |
79 | NIK/NF-kappaB signaling (GO:0038061) | 3.70010209 |
80 | negative regulation of cell killing (GO:0031342) | 3.68343279 |
81 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.68343279 |
82 | positive regulation of immunoglobulin production (GO:0002639) | 3.67402218 |
83 | regulation of isotype switching (GO:0045191) | 3.66288313 |
84 | regulation of natural killer cell differentiation (GO:0032823) | 3.62313500 |
85 | regulation of T-helper cell differentiation (GO:0045622) | 3.57930626 |
86 | regulation of immunoglobulin production (GO:0002637) | 3.57306584 |
87 | regulation of immunoglobulin mediated immune response (GO:0002889) | 3.56509544 |
88 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 3.55454255 |
89 | alpha-beta T cell activation involved in immune response (GO:0002287) | 3.55454255 |
90 | T cell differentiation involved in immune response (GO:0002292) | 3.55454255 |
91 | regulation of interleukin-12 production (GO:0032655) | 3.55070838 |
92 | regulation of T cell tolerance induction (GO:0002664) | 3.55034417 |
93 | myeloid dendritic cell activation (GO:0001773) | 3.54502580 |
94 | positive regulation of interleukin-12 production (GO:0032735) | 3.52981912 |
95 | T cell homeostasis (GO:0043029) | 3.52438020 |
96 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.52380014 |
97 | regulation of tolerance induction (GO:0002643) | 3.49664242 |
98 | positive regulation of macrophage differentiation (GO:0045651) | 3.49614684 |
99 | * positive regulation of activated T cell proliferation (GO:0042104) | 3.49602502 |
100 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.47967767 |
101 | Peyers patch development (GO:0048541) | 3.47967767 |
102 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 3.47785308 |
103 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 3.47785308 |
104 | T cell lineage commitment (GO:0002360) | 3.47097507 |
105 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 3.46904140 |
106 | regulation of B cell mediated immunity (GO:0002712) | 3.46419440 |
107 | negative regulation by host of viral transcription (GO:0043922) | 3.43392164 |
108 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 3.43297628 |
109 | negative regulation of T cell mediated immunity (GO:0002710) | 3.41014149 |
110 | positive regulation of cell killing (GO:0031343) | 3.40683107 |
111 | negative regulation of thymocyte apoptotic process (GO:0070244) | 3.39437409 |
112 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.38806016 |
113 | eosinophil migration (GO:0072677) | 3.36062895 |
114 | alpha-beta T cell differentiation (GO:0046632) | 3.31700168 |
115 | alpha-beta T cell activation (GO:0046631) | 3.29793323 |
116 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.27827194 |
117 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.25593946 |
118 | leukocyte aggregation (GO:0070486) | 3.25028462 |
119 | regulation of lymphocyte mediated immunity (GO:0002706) | 3.24465691 |
120 | regulation of T-helper 1 type immune response (GO:0002825) | 3.24300150 |
121 | lymphocyte chemotaxis (GO:0048247) | 3.23165223 |
122 | regulation of T cell cytokine production (GO:0002724) | 3.23164307 |
123 | * cellular response to interleukin-15 (GO:0071350) | 3.22868157 |
124 | positive regulation of lymphocyte migration (GO:2000403) | 3.21582547 |
125 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.21376780 |
126 | regulation of interleukin-1 beta secretion (GO:0050706) | 3.20795767 |
127 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 3.20021046 |
128 | regulation of chemokine biosynthetic process (GO:0045073) | 3.19947564 |
129 | positive regulation of cell fate commitment (GO:0010455) | 3.19808772 |
130 | positive regulation of leukocyte mediated immunity (GO:0002705) | 3.19444127 |
131 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 3.19109264 |
132 | regulation of mononuclear cell migration (GO:0071675) | 3.18341755 |
133 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.13952371 |
134 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.13288102 |
135 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.13059683 |
136 | positive regulation of T cell mediated immunity (GO:0002711) | 3.11189748 |
137 | T cell migration (GO:0072678) | 3.10768463 |
138 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.10310647 |
139 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.10193228 |
140 | regulation of response to interferon-gamma (GO:0060330) | 3.09792042 |
141 | regulation of cell killing (GO:0031341) | 3.09191665 |
142 | regulation of activation of Janus kinase activity (GO:0010533) | 3.08904717 |
143 | positive regulation of interleukin-10 production (GO:0032733) | 3.08851879 |
144 | T-helper cell differentiation (GO:0042093) | 3.08168958 |
145 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.08168958 |
146 | natural killer cell activation (GO:0030101) | 3.07895845 |
147 | positive regulation of astrocyte differentiation (GO:0048711) | 3.06902036 |
148 | positive regulation of T-helper 1 type immune response (GO:0002827) | 3.06012134 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.56096211 |
2 | * FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 7.48841292 |
3 | * STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.58879999 |
4 | * BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.04648865 |
5 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.96620072 |
6 | * STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.85666186 |
7 | MYC_22102868_ChIP-Seq_BL_Human | 3.74405674 |
8 | * STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.64585960 |
9 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.35873156 |
10 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.07053398 |
11 | * MYB_26560356_Chip-Seq_TH2_Human | 3.04985024 |
12 | MAF_26560356_Chip-Seq_TH1_Human | 2.81729116 |
13 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.79323154 |
14 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.70921534 |
15 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.63978643 |
16 | * FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.61338955 |
17 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.54610610 |
18 | * MYB_26560356_Chip-Seq_TH1_Human | 2.50405118 |
19 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.36771764 |
20 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.35901589 |
21 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.35633860 |
22 | UTX_26944678_Chip-Seq_JUKART_Human | 2.26526991 |
23 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.08203148 |
24 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.07330596 |
25 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.05833538 |
26 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.01538838 |
27 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.94931053 |
28 | * MAF_26560356_Chip-Seq_TH2_Human | 1.93977631 |
29 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.90173888 |
30 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.83231126 |
31 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.79266886 |
32 | GATA1_22025678_ChIP-Seq_K562_Human | 1.77888275 |
33 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.76883186 |
34 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.75280051 |
35 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.72843493 |
36 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.72682034 |
37 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.67498332 |
38 | * KDM2B_26808549_Chip-Seq_DND41_Human | 1.63518117 |
39 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.63011368 |
40 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.61810396 |
41 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.60770395 |
42 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.58379877 |
43 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.52172029 |
44 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.49088587 |
45 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.43669157 |
46 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.42767553 |
47 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.42131402 |
48 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.41641751 |
49 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.41411279 |
50 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.39653942 |
51 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39394659 |
52 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.37820956 |
53 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.37134214 |
54 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.36958183 |
55 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.34229860 |
56 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.34064864 |
57 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.31543506 |
58 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.30116224 |
59 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.28054074 |
60 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.26785822 |
61 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.24554832 |
62 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.23165612 |
63 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.21143476 |
64 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.19685050 |
65 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.18465637 |
66 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.15199041 |
67 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.13213871 |
68 | * KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.12294928 |
69 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.11282420 |
70 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.10525248 |
71 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.09968118 |
72 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.08999799 |
73 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.08287368 |
74 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.05378872 |
75 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 1.05014060 |
76 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.03931572 |
77 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.03613913 |
78 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.03046419 |
79 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.02865527 |
80 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02745164 |
81 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.02672376 |
82 | SPI1_23127762_ChIP-Seq_K562_Human | 1.02492620 |
83 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.02393586 |
84 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.00780196 |
85 | GATA3_26560356_Chip-Seq_TH2_Human | 1.00525089 |
86 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.99449343 |
87 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.97134585 |
88 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.95735880 |
89 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.95500275 |
90 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.94330241 |
91 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.93974066 |
92 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.91789760 |
93 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.91426966 |
94 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.90835701 |
95 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.90604535 |
96 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.90403382 |
97 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.87749859 |
98 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87287773 |
99 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.87011764 |
100 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.86924400 |
101 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.86765585 |
102 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.86630340 |
103 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.86116396 |
104 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.85053371 |
105 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.83550406 |
106 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.81802172 |
107 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.81640247 |
108 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.81490645 |
109 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.81411524 |
110 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.80936142 |
111 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.80006019 |
112 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.79588003 |
113 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.78068411 |
114 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.77747342 |
115 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.76835415 |
116 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.76303255 |
117 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.75823465 |
118 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.75506846 |
119 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.74477579 |
120 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.74160440 |
121 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.72879038 |
122 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.72874356 |
123 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.72419817 |
124 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.72131500 |
125 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.71612895 |
126 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.71532158 |
127 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.70752809 |
128 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.69322709 |
129 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.68837531 |
130 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.67521350 |
131 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.66813011 |
132 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.66216932 |
133 | GATA3_26560356_Chip-Seq_TH1_Human | 0.65954011 |
134 | * STAT1_20625510_ChIP-Seq_HELA_Human | 0.64911533 |
135 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.64795363 |
136 | * SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.64572014 |
137 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.64438873 |
138 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.64225077 |
139 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.63843876 |
140 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.63728443 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003763_abnormal_thymus_physiology | 4.53766334 |
2 | MP0003300_gastrointestinal_ulcer | 4.05757139 |
3 | MP0005671_abnormal_response_to | 3.98908608 |
4 | MP0000685_abnormal_immune_system | 3.75045547 |
5 | MP0003436_decreased_susceptibility_to | 3.30664531 |
6 | MP0001790_abnormal_immune_system | 3.24677777 |
7 | MP0005387_immune_system_phenotype | 3.24677777 |
8 | MP0001835_abnormal_antigen_presentation | 3.07527816 |
9 | MP0009333_abnormal_splenocyte_physiolog | 3.02992600 |
10 | * MP0001800_abnormal_humoral_immune | 2.92134326 |
11 | MP0002396_abnormal_hematopoietic_system | 2.86322346 |
12 | MP0005000_abnormal_immune_tolerance | 2.79502214 |
13 | MP0009785_altered_susceptibility_to | 2.68966645 |
14 | MP0002405_respiratory_system_inflammati | 2.67655470 |
15 | MP0000703_abnormal_thymus_morphology | 2.53779308 |
16 | * MP0002398_abnormal_bone_marrow | 2.52060357 |
17 | MP0002166_altered_tumor_susceptibility | 2.51431650 |
18 | * MP0002723_abnormal_immune_serum | 2.50309329 |
19 | MP0001873_stomach_inflammation | 2.47972381 |
20 | MP0003303_peritoneal_inflammation | 2.41663008 |
21 | * MP0003866_abnormal_defecation | 2.39436973 |
22 | * MP0002420_abnormal_adaptive_immunity | 2.32942745 |
23 | MP0001853_heart_inflammation | 2.32427124 |
24 | * MP0002452_abnormal_antigen_presenting | 2.29587421 |
25 | * MP0010155_abnormal_intestine_physiology | 2.28836379 |
26 | * MP0001819_abnormal_immune_cell | 2.28607395 |
27 | MP0002006_tumorigenesis | 2.17449710 |
28 | MP0005025_abnormal_response_to | 2.15304135 |
29 | MP0008057_abnormal_DNA_replication | 2.15285313 |
30 | * MP0000716_abnormal_immune_system | 2.11943429 |
31 | * MP0002722_abnormal_immune_system | 2.07655682 |
32 | MP0002933_joint_inflammation | 2.05512479 |
33 | * MP0000689_abnormal_spleen_morphology | 1.99842599 |
34 | MP0002148_abnormal_hypersensitivity_rea | 1.98854638 |
35 | MP0004808_abnormal_hematopoietic_stem | 1.94047438 |
36 | MP0004510_myositis | 1.89388000 |
37 | MP0010352_gastrointestinal_tract_polyps | 1.80053446 |
38 | * MP0002429_abnormal_blood_cell | 1.76084414 |
39 | MP0003724_increased_susceptibility_to | 1.64200539 |
40 | MP0000490_abnormal_crypts_of | 1.59489744 |
41 | MP0005076_abnormal_cell_differentiation | 1.58266371 |
42 | MP0000465_gastrointestinal_hemorrhage | 1.56717954 |
43 | * MP0001845_abnormal_inflammatory_respons | 1.55421788 |
44 | MP0004947_skin_inflammation | 1.55042934 |
45 | MP0006082_CNS_inflammation | 1.54181322 |
46 | MP0005310_abnormal_salivary_gland | 1.49636835 |
47 | MP0002419_abnormal_innate_immunity | 1.48915664 |
48 | MP0010094_abnormal_chromosome_stability | 1.47603272 |
49 | MP0005451_abnormal_body_composition | 1.46171330 |
50 | MP0003045_fibrosis | 1.32214543 |
51 | MP0004381_abnormal_hair_follicle | 1.31717199 |
52 | MP0003448_altered_tumor_morphology | 1.23957311 |
53 | MP0003693_abnormal_embryo_hatching | 1.22963810 |
54 | MP0001545_abnormal_hematopoietic_system | 1.20569469 |
55 | MP0005397_hematopoietic_system_phenotyp | 1.20569469 |
56 | MP0003077_abnormal_cell_cycle | 1.20406697 |
57 | MP0001533_abnormal_skeleton_physiology | 1.18471977 |
58 | MP0001881_abnormal_mammary_gland | 1.17974426 |
59 | MP0002163_abnormal_gland_morphology | 1.12432059 |
60 | MP0005464_abnormal_platelet_physiology | 1.08974257 |
61 | MP0005166_decreased_susceptibility_to | 1.08749252 |
62 | MP0002277_abnormal_respiratory_mucosa | 1.08590533 |
63 | MP0002019_abnormal_tumor_incidence | 1.07274456 |
64 | MP0003075_altered_response_to | 1.06863842 |
65 | MP0000569_abnormal_digit_pigmentation | 1.05813724 |
66 | MP0003111_abnormal_nucleus_morphology | 1.03983593 |
67 | MP0000858_altered_metastatic_potential | 1.03305634 |
68 | MP0002877_abnormal_melanocyte_morpholog | 0.99169428 |
69 | MP0008469_abnormal_protein_level | 0.96527073 |
70 | MP0002254_reproductive_system_inflammat | 0.95939355 |
71 | MP0008961_abnormal_basal_metabolism | 0.91635952 |
72 | MP0000350_abnormal_cell_proliferation | 0.89660745 |
73 | MP0004957_abnormal_blastocyst_morpholog | 0.87631983 |
74 | MP0008007_abnormal_cellular_replicative | 0.87611351 |
75 | MP0010307_abnormal_tumor_latency | 0.87399765 |
76 | MP0009278_abnormal_bone_marrow | 0.86935211 |
77 | MP0001851_eye_inflammation | 0.86492493 |
78 | MP0002693_abnormal_pancreas_physiology | 0.84806664 |
79 | MP0000604_amyloidosis | 0.82372468 |
80 | MP0002138_abnormal_hepatobiliary_system | 0.80007895 |
81 | MP0000343_altered_response_to | 0.77852658 |
82 | MP0002332_abnormal_exercise_endurance | 0.77711707 |
83 | MP0000627_abnormal_mammary_gland | 0.77520961 |
84 | MP0005058_abnormal_lysosome_morphology | 0.77100712 |
85 | MP0000372_irregular_coat_pigmentation | 0.76294177 |
86 | MP0003806_abnormal_nucleotide_metabolis | 0.75950621 |
87 | MP0000477_abnormal_intestine_morphology | 0.74495540 |
88 | MP0009764_decreased_sensitivity_to | 0.73194888 |
89 | MP0003172_abnormal_lysosome_physiology | 0.72713722 |
90 | MP0002998_abnormal_bone_remodeling | 0.71155500 |
91 | MP0003646_muscle_fatigue | 0.70551712 |
92 | MP0001919_abnormal_reproductive_system | 0.66952866 |
93 | MP0001348_abnormal_lacrimal_gland | 0.66709342 |
94 | MP0005381_digestive/alimentary_phenotyp | 0.65568401 |
95 | MP0001663_abnormal_digestive_system | 0.65411155 |
96 | MP0000313_abnormal_cell_death | 0.65387465 |
97 | MP0005023_abnormal_wound_healing | 0.64373742 |
98 | MP0003195_calcinosis | 0.63407559 |
99 | MP0005167_abnormal_blood-brain_barrier | 0.63317356 |
100 | MP0002009_preneoplasia | 0.63267405 |
101 | MP0001958_emphysema | 0.61893882 |
102 | MP0002139_abnormal_hepatobiliary_system | 0.60788858 |
103 | MP0008877_abnormal_DNA_methylation | 0.60337689 |
104 | MP0001730_embryonic_growth_arrest | 0.60335420 |
105 | MP0005379_endocrine/exocrine_gland_phen | 0.59682898 |
106 | MP0002088_abnormal_embryonic_growth/wei | 0.56972834 |
107 | MP0001727_abnormal_embryo_implantation | 0.56630661 |
108 | MP0008004_abnormal_stomach_pH | 0.56282974 |
109 | MP0009765_abnormal_xenobiotic_induced | 0.55971955 |
110 | MP0000609_abnormal_liver_physiology | 0.54660654 |
111 | MP0005075_abnormal_melanosome_morpholog | 0.54592841 |
112 | MP0009763_increased_sensitivity_to | 0.53789028 |
113 | MP0000371_diluted_coat_color | 0.53738608 |
114 | MP0009840_abnormal_foam_cell | 0.53294171 |
115 | MP0003984_embryonic_growth_retardation | 0.53287207 |
116 | MP0001501_abnormal_sleep_pattern | 0.52811353 |
117 | MP0001243_abnormal_dermal_layer | 0.52439452 |
118 | MP0008873_increased_physiological_sensi | 0.52308335 |
119 | MP0005165_increased_susceptibility_to | 0.51212222 |
120 | MP0001216_abnormal_epidermal_layer | 0.50461087 |
121 | MP0003453_abnormal_keratinocyte_physiol | 0.50452807 |
122 | MP0002086_abnormal_extraembryonic_tissu | 0.47808896 |
123 | MP0005390_skeleton_phenotype | 0.47181657 |
124 | MP0008058_abnormal_DNA_repair | 0.46739218 |
125 | MP0001849_ear_inflammation | 0.46222057 |
126 | MP0001672_abnormal_embryogenesis/_devel | 0.46029531 |
127 | MP0005380_embryogenesis_phenotype | 0.46029531 |
128 | MP0002136_abnormal_kidney_physiology | 0.46026985 |
129 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.44353583 |
130 | MP0003091_abnormal_cell_migration | 0.43849295 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Optic neuritis (HP:0100653) | 4.84613246 |
2 | Retrobulbar optic neuritis (HP:0100654) | 4.84613246 |
3 | Stomatitis (HP:0010280) | 4.65499013 |
4 | Myositis (HP:0100614) | 4.63863401 |
5 | * T lymphocytopenia (HP:0005403) | 4.62153310 |
6 | IgM deficiency (HP:0002850) | 4.57552385 |
7 | Panhypogammaglobulinemia (HP:0003139) | 4.56543813 |
8 | * Abnormality of T cell number (HP:0011839) | 4.46623545 |
9 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.46464155 |
10 | Recurrent cutaneous fungal infections (HP:0011370) | 4.46464155 |
11 | Abnormality of B cell number (HP:0010975) | 4.44399949 |
12 | B lymphocytopenia (HP:0010976) | 4.44399949 |
13 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.38392670 |
14 | Severe combined immunodeficiency (HP:0004430) | 4.37678816 |
15 | * Abnormality of T cells (HP:0002843) | 4.36548502 |
16 | * Recurrent fungal infections (HP:0002841) | 4.29928056 |
17 | Recurrent bronchitis (HP:0002837) | 4.16394535 |
18 | Orchitis (HP:0100796) | 4.10347842 |
19 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.08939424 |
20 | Abnormality of T cell physiology (HP:0011840) | 4.04708178 |
21 | Increased density of long bones (HP:0006392) | 3.89396819 |
22 | Combined immunodeficiency (HP:0005387) | 3.88658489 |
23 | Autoimmune thrombocytopenia (HP:0001973) | 3.82485588 |
24 | IgG deficiency (HP:0004315) | 3.78947099 |
25 | Eczematoid dermatitis (HP:0000976) | 3.76853072 |
26 | Pulmonary infiltrates (HP:0002113) | 3.70152976 |
27 | Abnormality of the fingertips (HP:0001211) | 3.66056127 |
28 | * Recurrent viral infections (HP:0004429) | 3.61949122 |
29 | Hemoptysis (HP:0002105) | 3.60928302 |
30 | Persistence of primary teeth (HP:0006335) | 3.56848493 |
31 | * Chronic diarrhea (HP:0002028) | 3.48027745 |
32 | Arterial thrombosis (HP:0004420) | 3.36651668 |
33 | Inflammation of the large intestine (HP:0002037) | 3.34888102 |
34 | Nasal polyposis (HP:0100582) | 3.30505376 |
35 | Gastrointestinal inflammation (HP:0004386) | 3.29996866 |
36 | Vasculitis (HP:0002633) | 3.28170602 |
37 | Chronic otitis media (HP:0000389) | 3.25437647 |
38 | Keratoconjunctivitis sicca (HP:0001097) | 3.23039543 |
39 | Gastrointestinal infarctions (HP:0005244) | 3.20139549 |
40 | Thrombocytosis (HP:0001894) | 3.17982027 |
41 | Abnormality of macrophages (HP:0004311) | 3.17249918 |
42 | * IgA deficiency (HP:0002720) | 3.05881057 |
43 | Eosinophilia (HP:0001880) | 3.03295025 |
44 | Keratoconjunctivitis (HP:0001096) | 2.96636333 |
45 | Abnormality of glycolipid metabolism (HP:0010969) | 2.95896122 |
46 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.95896122 |
47 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.95896122 |
48 | Increased IgM level (HP:0003496) | 2.89706614 |
49 | Mediastinal lymphadenopathy (HP:0100721) | 2.89638327 |
50 | Lymphoma (HP:0002665) | 2.88159587 |
51 | Abnormality of eosinophils (HP:0001879) | 2.88086312 |
52 | Meningitis (HP:0001287) | 2.86745177 |
53 | Cheilitis (HP:0100825) | 2.85710448 |
54 | Increased IgE level (HP:0003212) | 2.83714868 |
55 | Autoimmune hemolytic anemia (HP:0001890) | 2.81083248 |
56 | Leukocytosis (HP:0001974) | 2.74998753 |
57 | Acute myeloid leukemia (HP:0004808) | 2.73922628 |
58 | Polyneuropathy (HP:0001271) | 2.72266046 |
59 | Recurrent bacterial skin infections (HP:0005406) | 2.68856330 |
60 | Lymphopenia (HP:0001888) | 2.68165813 |
61 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.64070225 |
62 | Thyroiditis (HP:0100646) | 2.62992734 |
63 | Granulocytopenia (HP:0001913) | 2.61361570 |
64 | Abnormality of the nasal mucosa (HP:0000433) | 2.60995445 |
65 | Chest pain (HP:0100749) | 2.58843467 |
66 | Gangrene (HP:0100758) | 2.58209093 |
67 | Encephalitis (HP:0002383) | 2.52015167 |
68 | Pulmonary embolism (HP:0002204) | 2.50665177 |
69 | Aplastic anemia (HP:0001915) | 2.50322429 |
70 | Amaurosis fugax (HP:0100576) | 2.47308507 |
71 | Abnormality of the pericardium (HP:0001697) | 2.38663749 |
72 | Hypoproteinemia (HP:0003075) | 2.37129993 |
73 | Recurrent abscess formation (HP:0002722) | 2.33949715 |
74 | Cutis marmorata (HP:0000965) | 2.33796886 |
75 | Fatigue (HP:0012378) | 2.28780791 |
76 | Vacuolated lymphocytes (HP:0001922) | 2.27340712 |
77 | Gastrointestinal stroma tumor (HP:0100723) | 2.27157319 |
78 | Hypergammaglobulinemia (HP:0010702) | 2.26584632 |
79 | Pulmonary fibrosis (HP:0002206) | 2.26174389 |
80 | Bronchitis (HP:0012387) | 2.24559205 |
81 | Recurrent skin infections (HP:0001581) | 2.21942384 |
82 | Chronic obstructive pulmonary disease (HP:0006510) | 2.12480965 |
83 | Obstructive lung disease (HP:0006536) | 2.12480965 |
84 | Recurrent sinusitis (HP:0011108) | 2.12360321 |
85 | Basal cell carcinoma (HP:0002671) | 2.11540325 |
86 | Parakeratosis (HP:0001036) | 2.11331662 |
87 | Abnormality of the endocardium (HP:0004306) | 2.07445281 |
88 | Pustule (HP:0200039) | 2.04761917 |
89 | Abnormality of the prostate (HP:0008775) | 2.04140653 |
90 | * Joint swelling (HP:0001386) | 2.03939537 |
91 | Skin rash (HP:0000988) | 2.03510681 |
92 | Ureteral stenosis (HP:0000071) | 2.03190332 |
93 | Abnormality of the pleura (HP:0002103) | 2.01805857 |
94 | Acne (HP:0001061) | 1.99412551 |
95 | Gingival bleeding (HP:0000225) | 1.98903510 |
96 | Somatic mutation (HP:0001428) | 1.96810174 |
97 | Increased serum ferritin (HP:0003281) | 1.96545637 |
98 | Acute hepatic failure (HP:0006554) | 1.96297312 |
99 | Agammaglobulinemia (HP:0004432) | 1.96139512 |
100 | Interstitial pulmonary disease (HP:0006530) | 1.95562265 |
101 | Periodontitis (HP:0000704) | 1.94074500 |
102 | Abnormality of the peritoneum (HP:0002585) | 1.93824273 |
103 | Spontaneous hematomas (HP:0007420) | 1.93358431 |
104 | Thrombophlebitis (HP:0004418) | 1.91565302 |
105 | Leukopenia (HP:0001882) | 1.91493367 |
106 | Ureteral obstruction (HP:0006000) | 1.90429321 |
107 | Dyschromatopsia (HP:0007641) | 1.88798557 |
108 | Adactyly (HP:0009776) | 1.88773058 |
109 | Anorexia (HP:0002039) | 1.85587142 |
110 | Abnormal platelet volume (HP:0011876) | 1.84522167 |
111 | Gingivitis (HP:0000230) | 1.83823155 |
112 | Verrucae (HP:0200043) | 1.83649576 |
113 | Papilloma (HP:0012740) | 1.83649576 |
114 | Esophageal varix (HP:0002040) | 1.82825379 |
115 | Anhidrosis (HP:0000970) | 1.81851999 |
116 | Dysmetric saccades (HP:0000641) | 1.81316136 |
117 | Glomerulopathy (HP:0100820) | 1.81280736 |
118 | Hematochezia (HP:0002573) | 1.79670431 |
119 | Hypoplasia of the thymus (HP:0000778) | 1.78246030 |
120 | Keratitis (HP:0000491) | 1.77814873 |
121 | Episodic fever (HP:0001954) | 1.77752534 |
122 | Emphysema (HP:0002097) | 1.77497987 |
123 | Volvulus (HP:0002580) | 1.77114143 |
124 | * Arthralgia (HP:0002829) | 1.75809344 |
125 | Skull defect (HP:0001362) | 1.75260914 |
126 | Porencephaly (HP:0002132) | 1.75002324 |
127 | Systemic lupus erythematosus (HP:0002725) | 1.71406995 |
128 | Retinopathy (HP:0000488) | 1.71103690 |
129 | Pancreatitis (HP:0001733) | 1.69445494 |
130 | Alveolar cell carcinoma (HP:0006519) | 1.69297147 |
131 | Paresthesia (HP:0003401) | 1.67895581 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TXK | 6.54961758 |
2 | MAP4K1 | 5.23873276 |
3 | JAK3 | 3.85546048 |
4 | EEF2K | 3.77272199 |
5 | ZAP70 | 2.80365644 |
6 | ITK | 2.71454160 |
7 | FGFR4 | 2.47666228 |
8 | GRK7 | 2.46591601 |
9 | MAP3K14 | 2.39593111 |
10 | CDK12 | 2.15272299 |
11 | STK10 | 2.03923252 |
12 | EPHB1 | 1.96380389 |
13 | MATK | 1.95517552 |
14 | RIPK4 | 1.90109334 |
15 | EPHA3 | 1.89528555 |
16 | FGFR3 | 1.88724385 |
17 | TSSK6 | 1.85771126 |
18 | TYK2 | 1.84825309 |
19 | ADRBK2 | 1.81141145 |
20 | NLK | 1.77256383 |
21 | TEC | 1.73063909 |
22 | TAOK2 | 1.63163025 |
23 | CDC7 | 1.57956585 |
24 | JAK1 | 1.53687899 |
25 | LCK | 1.53393788 |
26 | MAP2K6 | 1.52105783 |
27 | IRAK4 | 1.47947523 |
28 | ALK | 1.43131391 |
29 | TRIB3 | 1.41541179 |
30 | SYK | 1.41218846 |
31 | HCK | 1.39834332 |
32 | KDR | 1.39663109 |
33 | PIM2 | 1.37136023 |
34 | BTK | 1.36082172 |
35 | BMPR2 | 1.32147881 |
36 | EIF2AK3 | 1.31645419 |
37 | MAP3K7 | 1.27053578 |
38 | IKBKB | 1.22745993 |
39 | MAP3K10 | 1.20066310 |
40 | PKN2 | 1.18598772 |
41 | PIM1 | 1.18444849 |
42 | CHUK | 1.16255447 |
43 | GRK6 | 1.15060052 |
44 | IKBKE | 1.13766281 |
45 | CDK4 | 1.10088012 |
46 | JAK2 | 1.07840732 |
47 | CLK1 | 1.05687606 |
48 | PRPF4B | 1.05008705 |
49 | PRKCQ | 1.02465045 |
50 | LRRK2 | 1.01275395 |
51 | SIK2 | 1.00733830 |
52 | CSK | 0.99860927 |
53 | TBK1 | 0.99085015 |
54 | RIPK1 | 0.98761240 |
55 | NME1 | 0.95527662 |
56 | CAMKK2 | 0.94596573 |
57 | MST4 | 0.94354377 |
58 | MOS | 0.91387292 |
59 | MAPK11 | 0.89708912 |
60 | PIK3CA | 0.87714238 |
61 | CDK6 | 0.87005124 |
62 | MAPKAPK3 | 0.84960938 |
63 | FES | 0.84873260 |
64 | BRD4 | 0.84079413 |
65 | TLK1 | 0.83035532 |
66 | PASK | 0.82251749 |
67 | RPS6KA4 | 0.78784049 |
68 | TESK2 | 0.78335871 |
69 | NEK2 | 0.76405370 |
70 | PTK6 | 0.73664108 |
71 | NME2 | 0.72791118 |
72 | PRKCH | 0.72326285 |
73 | BLK | 0.72115750 |
74 | MAP3K13 | 0.71929787 |
75 | RPS6KB2 | 0.70469660 |
76 | TGFBR2 | 0.69241223 |
77 | HIPK2 | 0.64160223 |
78 | TAOK3 | 0.63600083 |
79 | MAP3K8 | 0.62616318 |
80 | CHEK1 | 0.60990533 |
81 | LYN | 0.60318389 |
82 | MAP3K3 | 0.60254213 |
83 | EIF2AK2 | 0.59408863 |
84 | TAOK1 | 0.58480254 |
85 | IRAK1 | 0.57868939 |
86 | FGFR1 | 0.53950193 |
87 | PDGFRB | 0.53371587 |
88 | SIK3 | 0.52394439 |
89 | CDK9 | 0.51087555 |
90 | NUAK1 | 0.51041899 |
91 | DAPK1 | 0.50915490 |
92 | MAP3K11 | 0.48308385 |
93 | MAPKAPK2 | 0.47049183 |
94 | WNK4 | 0.46036151 |
95 | ATR | 0.45879103 |
96 | DAPK2 | 0.45502206 |
97 | KIT | 0.43318493 |
98 | PDK1 | 0.43153398 |
99 | BCR | 0.42959932 |
100 | PLK3 | 0.42953460 |
101 | RAF1 | 0.42754070 |
102 | BCKDK | 0.42280711 |
103 | FGR | 0.42004778 |
104 | STK24 | 0.41598056 |
105 | STK4 | 0.41162602 |
106 | TNK2 | 0.40843472 |
107 | RPS6KB1 | 0.40785410 |
108 | MARK3 | 0.39714404 |
109 | EGFR | 0.38765494 |
110 | RPS6KA5 | 0.37314139 |
111 | MTOR | 0.37281392 |
112 | ROCK2 | 0.36988752 |
113 | MELK | 0.36611421 |
114 | PAK2 | 0.35550330 |
115 | MAP3K12 | 0.35208912 |
116 | ATM | 0.35130999 |
117 | TYRO3 | 0.34672205 |
118 | FYN | 0.34334608 |
119 | MAP2K3 | 0.33060990 |
120 | NTRK2 | 0.32768741 |
121 | TGFBR1 | 0.32548361 |
122 | SGK3 | 0.30841516 |
123 | SRPK1 | 0.30807808 |
124 | SIK1 | 0.30654437 |
125 | ACVR1B | 0.29989443 |
126 | CSF1R | 0.29489596 |
127 | DDR2 | 0.29365505 |
128 | IGF1R | 0.28908720 |
129 | CDK2 | 0.28575088 |
130 | MAP3K5 | 0.28555540 |
131 | IRAK3 | 0.28046394 |
132 | CSNK1D | 0.27997102 |
133 | MAP3K1 | 0.27555629 |
134 | MAP4K2 | 0.27074243 |
135 | MARK2 | 0.27070440 |
136 | VRK2 | 0.26900482 |
137 | CDC42BPA | 0.26403110 |
138 | INSR | 0.25368586 |
139 | RET | 0.24663297 |
140 | CAMKK1 | 0.23366882 |
141 | MAPK3 | 0.20332714 |
142 | MAPK4 | 0.14499284 |
143 | NTRK1 | 0.11233181 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 4.51461203 |
2 | Allograft rejection_Homo sapiens_hsa05330 | 3.97271277 |
3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.69052898 |
4 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.38811624 |
5 | Asthma_Homo sapiens_hsa05310 | 3.16360828 |
6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.12871925 |
7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.84851016 |
8 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.81957778 |
9 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.71455262 |
10 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.69691016 |
11 | * Measles_Homo sapiens_hsa05162 | 2.37432084 |
12 | * Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 2.36662268 |
13 | Proteasome_Homo sapiens_hsa03050 | 2.03969704 |
14 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.89306746 |
15 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.80440236 |
16 | * Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.68432243 |
17 | Leishmaniasis_Homo sapiens_hsa05140 | 1.66004072 |
18 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.63341802 |
19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.57992133 |
20 | Viral myocarditis_Homo sapiens_hsa05416 | 1.56062651 |
21 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.55808589 |
22 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.43473745 |
23 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.43263007 |
24 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.39284062 |
25 | * Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.39130638 |
26 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.38425648 |
27 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.36791152 |
28 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.36083222 |
29 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.32296440 |
30 | DNA replication_Homo sapiens_hsa03030 | 1.31813780 |
31 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.26813577 |
32 | Hepatitis B_Homo sapiens_hsa05161 | 1.26341743 |
33 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.24596945 |
34 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.20884828 |
35 | * HTLV-I infection_Homo sapiens_hsa05166 | 1.19615002 |
36 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.18704178 |
37 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.16273113 |
38 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.15263412 |
39 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.10474556 |
40 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.06246967 |
41 | Spliceosome_Homo sapiens_hsa03040 | 1.00984836 |
42 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.97955112 |
43 | Influenza A_Homo sapiens_hsa05164 | 0.96993491 |
44 | Legionellosis_Homo sapiens_hsa05134 | 0.95001848 |
45 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.92398537 |
46 | RNA transport_Homo sapiens_hsa03013 | 0.92352304 |
47 | Apoptosis_Homo sapiens_hsa04210 | 0.91724514 |
48 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.91066134 |
49 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.89323670 |
50 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.88795181 |
51 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.87804911 |
52 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.80273523 |
53 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.79833995 |
54 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.79553029 |
55 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.79447599 |
56 | Mismatch repair_Homo sapiens_hsa03430 | 0.78579604 |
57 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.76759575 |
58 | Cell cycle_Homo sapiens_hsa04110 | 0.75522650 |
59 | Shigellosis_Homo sapiens_hsa05131 | 0.75111895 |
60 | Base excision repair_Homo sapiens_hsa03410 | 0.73672047 |
61 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.70842209 |
62 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.69177917 |
63 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.68382270 |
64 | Prion diseases_Homo sapiens_hsa05020 | 0.68077582 |
65 | RNA degradation_Homo sapiens_hsa03018 | 0.67202839 |
66 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.64558778 |
67 | Ribosome_Homo sapiens_hsa03010 | 0.64408965 |
68 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.64332947 |
69 | Tuberculosis_Homo sapiens_hsa05152 | 0.64239707 |
70 | Colorectal cancer_Homo sapiens_hsa05210 | 0.63089384 |
71 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.61002883 |
72 | Lysosome_Homo sapiens_hsa04142 | 0.59765451 |
73 | Hepatitis C_Homo sapiens_hsa05160 | 0.57873425 |
74 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.57602201 |
75 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.56460338 |
76 | Malaria_Homo sapiens_hsa05144 | 0.56235246 |
77 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.55012109 |
78 | Prostate cancer_Homo sapiens_hsa05215 | 0.53187446 |
79 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.49958677 |
80 | Pertussis_Homo sapiens_hsa05133 | 0.49908351 |
81 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.48910254 |
82 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.48884469 |
83 | Protein export_Homo sapiens_hsa03060 | 0.48587096 |
84 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.47897466 |
85 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.46433314 |
86 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.43834075 |
87 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.43165442 |
88 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.43040871 |
89 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.42930158 |
90 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.41599197 |
91 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.41571872 |
92 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.41326207 |
93 | Homologous recombination_Homo sapiens_hsa03440 | 0.41053296 |
94 | Salmonella infection_Homo sapiens_hsa05132 | 0.39019346 |
95 | Platelet activation_Homo sapiens_hsa04611 | 0.36167995 |
96 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.35538111 |
97 | Thyroid cancer_Homo sapiens_hsa05216 | 0.35126116 |
98 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.32362117 |
99 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.31305342 |
100 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.31248704 |
101 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.30830086 |
102 | Pathways in cancer_Homo sapiens_hsa05200 | 0.28730444 |
103 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.28505399 |
104 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.27809266 |
105 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.26273465 |
106 | Lysine degradation_Homo sapiens_hsa00310 | 0.26141419 |
107 | Insulin resistance_Homo sapiens_hsa04931 | 0.25852177 |
108 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.25179533 |
109 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.24943895 |
110 | Phagosome_Homo sapiens_hsa04145 | 0.24515169 |
111 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.23161337 |
112 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.22449223 |
113 | Amoebiasis_Homo sapiens_hsa05146 | 0.21868518 |
114 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.21723448 |
115 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.19392586 |
116 | Other glycan degradation_Homo sapiens_hsa00511 | 0.18868257 |
117 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.17352779 |
118 | Endometrial cancer_Homo sapiens_hsa05213 | 0.17072141 |
119 | RNA polymerase_Homo sapiens_hsa03020 | 0.14975365 |
120 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.14828794 |
121 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.13027874 |
122 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.08122056 |
123 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.06407817 |
124 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.05084836 |
125 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.04762263 |
126 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.03467550 |
127 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.02111084 |
128 | Basal transcription factors_Homo sapiens_hsa03022 | -0.0613151 |
129 | Bladder cancer_Homo sapiens_hsa05219 | -0.0499782 |
130 | Linoleic acid metabolism_Homo sapiens_hsa00591 | -0.0471889 |
131 | Mineral absorption_Homo sapiens_hsa04978 | -0.0011442 |