IL4I1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous antigen (GO:0019883)7.70539438
2NIK/NF-kappaB signaling (GO:0038061)7.60645913
3regulation of dendritic cell antigen processing and presentation (GO:0002604)7.28740571
4positive regulation of antigen processing and presentation (GO:0002579)5.95892150
5antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.48153725
6antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.48153725
7regulation of T-helper 1 cell differentiation (GO:0045625)5.18025808
8regulation of antigen processing and presentation (GO:0002577)5.13792842
9regulation of activation of Janus kinase activity (GO:0010533)5.11652998
10positive regulation of interleukin-12 production (GO:0032735)5.06820618
11positive regulation of natural killer cell differentiation (GO:0032825)4.95048535
12myeloid dendritic cell differentiation (GO:0043011)4.83325891
13regulation of RIG-I signaling pathway (GO:0039535)4.68601730
14positive regulation of type 2 immune response (GO:0002830)4.65264013
15positive regulation of T-helper cell differentiation (GO:0045624)4.64733947
16positive regulation of heat generation (GO:0031652)4.61152428
17positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)4.57184453
18natural killer cell mediated cytotoxicity (GO:0042267)4.52502044
19natural killer cell mediated immunity (GO:0002228)4.52502044
20positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)4.47854056
21negative thymic T cell selection (GO:0045060)4.44810321
22negative regulation of interleukin-12 production (GO:0032695)4.42963944
23regulation of fever generation (GO:0031620)4.42929373
24immunoglobulin mediated immune response (GO:0016064)4.38521292
25type I interferon signaling pathway (GO:0060337)4.33191078
26cellular response to type I interferon (GO:0071357)4.33191078
27myeloid dendritic cell activation (GO:0001773)4.30086708
28response to type I interferon (GO:0034340)4.29384423
29neutrophil activation involved in immune response (GO:0002283)4.29221504
30positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.27029618
31cellular response to zinc ion (GO:0071294)4.26599459
32negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.24877911
33negative regulation of cell killing (GO:0031342)4.24877911
34positive regulation of interferon-alpha production (GO:0032727)4.24589158
35regulation of chronic inflammatory response (GO:0002676)4.24024904
36T-helper 1 type immune response (GO:0042088)4.23476520
37interferon-gamma-mediated signaling pathway (GO:0060333)4.22524658
38positive regulation of gamma-delta T cell activation (GO:0046645)4.15190737
39regulation of interleukin-12 biosynthetic process (GO:0045075)4.13995149
40regulation of vitamin D biosynthetic process (GO:0060556)4.11613059
41neutrophil activation (GO:0042119)4.10777782
42negative T cell selection (GO:0043383)4.07420004
43dendritic cell differentiation (GO:0097028)4.00742359
44regulation of interferon-alpha production (GO:0032647)3.98723201
45granulocyte activation (GO:0036230)3.97360937
46regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.95742426
47antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.93626860
48regulation of interleukin-12 production (GO:0032655)3.92469373
49regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)3.89994208
50positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)3.87369953
51regulation of T-helper cell differentiation (GO:0045622)3.84731410
52regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)3.74928887
53positive regulation of interleukin-2 production (GO:0032743)3.69771665
54positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.69401362
55regulation of hypersensitivity (GO:0002883)3.68130549
56B cell mediated immunity (GO:0019724)3.67781932
57lipopolysaccharide-mediated signaling pathway (GO:0031663)3.66494741
58regulation of alpha-beta T cell proliferation (GO:0046640)3.66381132
59response to muramyl dipeptide (GO:0032495)3.65511113
60regulation of memory T cell differentiation (GO:0043380)3.65147017
61defense response to protozoan (GO:0042832)3.63110291
62JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.59749555
63positive regulation of alpha-beta T cell proliferation (GO:0046641)3.59269401
64tumor necrosis factor-mediated signaling pathway (GO:0033209)3.53313811
65T cell migration (GO:0072678)3.52023649
66negative regulation of myeloid cell apoptotic process (GO:0033033)3.49934589
67regulation of T-helper 2 cell differentiation (GO:0045628)3.48571243
68cellular response to exogenous dsRNA (GO:0071360)3.48504395
69T-helper cell differentiation (GO:0042093)3.48122789
70CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.48122789
71positive regulation of granulocyte chemotaxis (GO:0071624)3.48023074
72positive regulation of humoral immune response (GO:0002922)3.46248734
73positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.44084030
74growth hormone receptor signaling pathway (GO:0060396)3.43651143
75positive regulation of prostaglandin secretion (GO:0032308)3.42903223
76regulation of heat generation (GO:0031650)3.42896973
77positive regulation of T-helper 1 type immune response (GO:0002827)3.37231089
78regulation of natural killer cell differentiation (GO:0032823)3.36951662
79leukocyte mediated cytotoxicity (GO:0001909)3.36563753
80positive regulation of neutrophil migration (GO:1902624)3.35054867
81positive regulation of neutrophil chemotaxis (GO:0090023)3.35054867
82regulation of cytokine secretion involved in immune response (GO:0002739)3.34788332
83cellular response to interferon-beta (GO:0035458)3.34108899
84dendritic cell chemotaxis (GO:0002407)3.30700621
85regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)3.29629993
86positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.28642890
87positive regulation of B cell differentiation (GO:0045579)3.27076569
88cellular response to interferon-gamma (GO:0071346)3.26987074
89positive regulation of interleukin-17 production (GO:0032740)3.26528435
90negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.25142586
91regulation of prostaglandin secretion (GO:0032306)3.24310753
92macrophage activation involved in immune response (GO:0002281)3.23664110
93negative regulation of inflammatory response to antigenic stimulus (GO:0002862)3.22825292
94monocyte chemotaxis (GO:0002548)3.20715317
95positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.20129455
96response to peptidoglycan (GO:0032494)3.19115133
97positive regulation of natural killer cell activation (GO:0032816)3.18617615
98positive regulation of osteoclast differentiation (GO:0045672)3.17924505
99natural killer cell differentiation (GO:0001779)3.17810471
100regulation of vitamin metabolic process (GO:0030656)3.17647145
101response to interferon-gamma (GO:0034341)3.17116019
102regulation of immunoglobulin secretion (GO:0051023)3.16358449
103lymphocyte mediated immunity (GO:0002449)3.16145132
104regulation of T-helper 1 type immune response (GO:0002825)3.15351205
105negative regulation of cytokine production involved in immune response (GO:0002719)3.14973645
106regulation of mononuclear cell migration (GO:0071675)3.13227318
107bone resorption (GO:0045453)3.13055739
108regulation of inflammatory response to antigenic stimulus (GO:0002861)3.13037182
109negative regulation of T cell mediated immunity (GO:0002710)3.11230788
110regulation of T cell mediated cytotoxicity (GO:0001914)3.10408228
111CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.10192721
112germinal center formation (GO:0002467)3.09700801
113positive regulation of chemokine biosynthetic process (GO:0045080)3.08955779
114regulation of type I interferon-mediated signaling pathway (GO:0060338)3.07773011
115regulation of interferon-beta biosynthetic process (GO:0045357)3.07253933
116positive regulation of interleukin-10 production (GO:0032733)3.05404406
117modulation by symbiont of host immune response (GO:0052553)3.05329077
118positive regulation by symbiont of host defense response (GO:0052509)3.05329077
119modulation by symbiont of host defense response (GO:0052031)3.05329077
120modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.05329077
121modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.05329077
122positive regulation by organism of defense response of other organism involved in symbiotic interact3.05329077
123regulation of interferon-gamma biosynthetic process (GO:0045072)3.04537992
124positive regulation of interferon-gamma production (GO:0032729)3.03887376
125regulation of B cell differentiation (GO:0045577)3.03245289
126negative regulation of viral genome replication (GO:0045071)3.02378400
127positive regulation of macrophage cytokine production (GO:0060907)3.02002449
128cytokine secretion (GO:0050663)3.01032847
129thymic T cell selection (GO:0045061)3.00859316
130alpha-beta T cell differentiation involved in immune response (GO:0002293)3.00744057
131alpha-beta T cell activation involved in immune response (GO:0002287)3.00744057
132T cell differentiation involved in immune response (GO:0002292)3.00744057
133positive regulation of alpha-beta T cell differentiation (GO:0046638)2.99763662
134positive regulation of defense response to virus by host (GO:0002230)2.99176070
135adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.98753975
136regulation of B cell receptor signaling pathway (GO:0050855)2.98723182
137positive regulation of activated T cell proliferation (GO:0042104)2.98225700
138response to protozoan (GO:0001562)2.97976685
139positive regulation of T cell cytokine production (GO:0002726)2.97570287
140positive regulation of NF-kappaB import into nucleus (GO:0042346)2.94850048
141regulation of defense response to virus by host (GO:0050691)2.94405845
142regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.94336749
143tolerance induction (GO:0002507)2.91064436
144regulation of podosome assembly (GO:0071801)2.88439493
145positive regulation of B cell mediated immunity (GO:0002714)2.85027811
146positive regulation of immunoglobulin mediated immune response (GO:0002891)2.85027811

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human8.53978900
2IRF8_21731497_ChIP-ChIP_J774_Mouse6.51936534
3IRF8_22096565_ChIP-ChIP_GC-B_Mouse5.76227121
4* IRF1_21803131_ChIP-Seq_MONOCYTES_Human5.09836477
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.97339882
6IRF8_27001747_Chip-Seq_BMDM_Mouse4.06442568
7* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human3.72216173
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.61928405
9* SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.32519515
10STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.24114030
11STAT4_19710469_ChIP-ChIP_TH1__Mouse3.07642853
12BP1_19119308_ChIP-ChIP_Hs578T_Human3.01995535
13SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.01364457
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.93164179
15NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.91699318
16MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.65155454
17TP63_17297297_ChIP-ChIP_HaCaT_Human2.55278149
18STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.38460015
19Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.36492952
20NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.29586139
21MYB_21317192_ChIP-Seq_ERMYB_Mouse2.29371523
22MYB_26560356_Chip-Seq_TH2_Human2.06065781
23VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.03580471
24MAF_26560356_Chip-Seq_TH1_Human2.02485043
25SMAD_19615063_ChIP-ChIP_OVARY_Human1.85654134
26RUNX_20019798_ChIP-Seq_JUKART_Human1.85309894
27MYB_26560356_Chip-Seq_TH1_Human1.82417066
28FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.80926294
29NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.79938479
30SPI1_23547873_ChIP-Seq_NB4_Human1.73556072
31VDR_24787735_ChIP-Seq_THP-1_Human1.71699669
32VDR_24763502_ChIP-Seq_THP-1_Human1.67721835
33THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.63470244
34BRD4_27068464_Chip-Seq_AML-cells_Mouse1.59608400
35VDR_21846776_ChIP-Seq_THP-1_Human1.57158262
36PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.51688083
37STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.49215236
38PU_27001747_Chip-Seq_BMDM_Mouse1.47353323
39* LXR_22292898_ChIP-Seq_THP-1_Human1.44505465
40ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.41815501
41GATA3_27048872_Chip-Seq_THYMUS_Human1.35698622
42* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.35493762
43SPI1_23127762_ChIP-Seq_K562_Human1.34346807
44NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.33498514
45E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.33159736
46PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.32095882
47CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.29297378
48MYC_22102868_ChIP-Seq_BL_Human1.28985350
49GATA3_26560356_Chip-Seq_TH2_Human1.28600407
50CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.22942534
51RUNX1_22412390_ChIP-Seq_EML_Mouse1.21680302
52VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.21409540
53NOTCH1_21737748_ChIP-Seq_TLL_Human1.19337799
54IKZF1_21737484_ChIP-ChIP_HCT116_Human1.15645152
55* MAF_26560356_Chip-Seq_TH2_Human1.13321875
56RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.12680518
57SCL_19346495_ChIP-Seq_HPC-7_Human1.12178894
58CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.11622596
59GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.11073893
60SMRT_27268052_Chip-Seq_Bcells_Human1.10817999
61TCF7_22412390_ChIP-Seq_EML_Mouse1.09733302
62GATA1_22025678_ChIP-Seq_K562_Human1.09211731
63CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08118079
64LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07844905
65SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06763494
66TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.06208614
67ELF1_20517297_ChIP-Seq_JURKAT_Human1.06037049
68CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.05768415
69PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.05141206
70TFEB_21752829_ChIP-Seq_HELA_Human1.03682929
71UTX_26944678_Chip-Seq_JUKART_Human1.01981372
72TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.01755391
73GATA1_19941826_ChIP-Seq_K562_Human1.00248230
74BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.99224676
75TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98844875
76SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.95768992
77MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.94981501
78KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.93979792
79FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.89882440
80SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.89303234
81GATA2_22383799_ChIP-Seq_G1ME_Mouse0.88404204
82TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.87922695
83GATA2_21666600_ChIP-Seq_HMVEC_Human0.87302624
84FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.87141636
85SRY_22984422_ChIP-ChIP_TESTIS_Rat0.87027425
86PU.1_20513432_ChIP-Seq_Bcells_Mouse0.86113781
87KDM2B_26808549_Chip-Seq_SUP-B15_Human0.85746717
88ERG_20887958_ChIP-Seq_HPC-7_Mouse0.85538256
89ELK3_25401928_ChIP-Seq_HUVEC_Human0.85325685
90LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.85236204
91TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.85076350
92PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.79891954
93ELF1_17652178_ChIP-ChIP_JURKAT_Human0.78833249
94KDM2B_26808549_Chip-Seq_DND41_Human0.78181999
95* HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.76992496
96EGR1_19032775_ChIP-ChIP_M12_Human0.74386608
97CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.73896246
98GATA1_19941827_ChIP-Seq_MEL_Mouse0.72607345
99CTCF_26484167_Chip-Seq_Bcells_Mouse0.69917829
100* SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.66814536
101* SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.66814536
102FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.65614515
103P300_27268052_Chip-Seq_Bcells_Human0.63979737
104GATA3_26560356_Chip-Seq_TH1_Human0.63645155
105GATA1_22383799_ChIP-Seq_G1ME_Mouse0.60356675
106SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.60278005
107FOXO3_23340844_ChIP-Seq_DLD1_Human0.60121973
108TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.59955986
109BCL6_27268052_Chip-Seq_Bcells_Human0.59731219
110BCOR_27268052_Chip-Seq_Bcells_Human0.58769636
111KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.58648332
112STAT1_20625510_ChIP-Seq_HELA_Human0.57281456
113JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.56406350
114KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.55911669
115JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.55532187
116GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.55518592

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation5.85087877
2MP0000685_abnormal_immune_system4.75125752
3MP0002254_reproductive_system_inflammat4.69351148
4MP0001348_abnormal_lacrimal_gland3.97794283
5MP0004510_myositis3.93540866
6MP0005387_immune_system_phenotype3.74808124
7MP0001790_abnormal_immune_system3.74808124
8MP0002138_abnormal_hepatobiliary_system3.53265314
9MP0002148_abnormal_hypersensitivity_rea3.53078217
10MP0005671_abnormal_response_to3.43288396
11MP0009785_altered_susceptibility_to3.26345215
12MP0001800_abnormal_humoral_immune3.05206608
13MP0005310_abnormal_salivary_gland3.02903871
14MP0005000_abnormal_immune_tolerance2.93310505
15MP0001346_abnormal_lacrimal_gland2.92302706
16MP0002452_abnormal_antigen_presenting2.69420718
17MP0002163_abnormal_gland_morphology2.59318943
18MP0002723_abnormal_immune_serum2.55094151
19MP0005025_abnormal_response_to2.54619789
20MP0003436_decreased_susceptibility_to2.49189283
21MP0002419_abnormal_innate_immunity2.28121243
22MP0001819_abnormal_immune_cell2.28086728
23MP0002420_abnormal_adaptive_immunity2.24705081
24MP0002166_altered_tumor_susceptibility2.18658822
25MP0006082_CNS_inflammation2.13785932
26MP0003303_peritoneal_inflammation2.07244782
27MP0002006_tumorigenesis2.05503967
28MP0001853_heart_inflammation2.03667878
29MP0002139_abnormal_hepatobiliary_system2.03558145
30MP0001873_stomach_inflammation1.97774469
31MP0002876_abnormal_thyroid_physiology1.92479084
32MP0002405_respiratory_system_inflammati1.82556980
33MP0000716_abnormal_immune_system1.82545248
34MP0002398_abnormal_bone_marrow1.78939232
35MP0003191_abnormal_cellular_cholesterol1.64006631
36MP0001845_abnormal_inflammatory_respons1.61091212
37MP0002277_abnormal_respiratory_mucosa1.57526609
38MP0004947_skin_inflammation1.54481117
39MP0003763_abnormal_thymus_physiology1.53432658
40MP0008057_abnormal_DNA_replication1.50128500
41MP0010155_abnormal_intestine_physiology1.46181701
42MP0002429_abnormal_blood_cell1.40474825
43MP0003195_calcinosis1.35084736
44MP0005167_abnormal_blood-brain_barrier1.31620844
45MP0003448_altered_tumor_morphology1.31214854
46MP0002877_abnormal_melanocyte_morpholog1.30864319
47MP0009333_abnormal_splenocyte_physiolog1.27220672
48MP0002722_abnormal_immune_system1.26223253
49MP0008469_abnormal_protein_level1.25702087
50MP0009764_decreased_sensitivity_to1.24818593
51MP0005451_abnormal_body_composition1.23250705
52MP0000689_abnormal_spleen_morphology1.22479824
53MP0005379_endocrine/exocrine_gland_phen1.20576185
54MP0003806_abnormal_nucleotide_metabolis1.15051022
55MP0000465_gastrointestinal_hemorrhage1.13220972
56MP0003724_increased_susceptibility_to1.12112061
57MP0001533_abnormal_skeleton_physiology1.06001782
58MP0000569_abnormal_digit_pigmentation1.05986838
59MP0003091_abnormal_cell_migration1.04685493
60MP0005076_abnormal_cell_differentiation1.04550943
61MP0005464_abnormal_platelet_physiology1.04499628
62MP0002009_preneoplasia1.04133475
63MP0005166_decreased_susceptibility_to1.03817268
64MP0010352_gastrointestinal_tract_polyps0.96635353
65MP0000858_altered_metastatic_potential0.95646549
66MP0005397_hematopoietic_system_phenotyp0.92970623
67MP0001545_abnormal_hematopoietic_system0.92970623
68MP0003183_abnormal_peptide_metabolism0.90339125
69MP0000703_abnormal_thymus_morphology0.89381464
70MP0003453_abnormal_keratinocyte_physiol0.89344863
71MP0000920_abnormal_myelination0.87860986
72MP0003656_abnormal_erythrocyte_physiolo0.87172367
73MP0008004_abnormal_stomach_pH0.86354090
74MP0003828_pulmonary_edema0.81637826
75MP0003690_abnormal_glial_cell0.80062059
76MP0003300_gastrointestinal_ulcer0.78673322
77MP0002332_abnormal_exercise_endurance0.78269902
78MP0009278_abnormal_bone_marrow0.74738165
79MP0003045_fibrosis0.72460846
80MP0005165_increased_susceptibility_to0.71790764
81MP0003795_abnormal_bone_structure0.71472317
82MP0001501_abnormal_sleep_pattern0.67675500
83MP0002693_abnormal_pancreas_physiology0.67244466
84MP0008874_decreased_physiological_sensi0.67203286
85MP0001881_abnormal_mammary_gland0.65563632
86MP0003172_abnormal_lysosome_physiology0.65203295
87MP0000613_abnormal_salivary_gland0.65108435
88MP0005647_abnormal_sex_gland0.64324991
89MP0010307_abnormal_tumor_latency0.63777135
90MP0002998_abnormal_bone_remodeling0.63763823
91MP0004782_abnormal_surfactant_physiolog0.62085366
92MP0009763_increased_sensitivity_to0.61264152
93MP0002136_abnormal_kidney_physiology0.60719220
94MP0000609_abnormal_liver_physiology0.60649846
95MP0003075_altered_response_to0.57308615
96MP0000604_amyloidosis0.57254798
97MP0000371_diluted_coat_color0.56990704
98MP0001542_abnormal_bone_strength0.56508171
99MP0006054_spinal_hemorrhage0.56380180
100MP0004808_abnormal_hematopoietic_stem0.55594498
101MP0003866_abnormal_defecation0.54712904
102MP0005164_abnormal_response_to0.53763265
103MP0000627_abnormal_mammary_gland0.53718038
104MP0002933_joint_inflammation0.53699278
105MP0002396_abnormal_hematopoietic_system0.53597979
106MP0001727_abnormal_embryo_implantation0.51611328
107MP0005645_abnormal_hypothalamus_physiol0.51040004
108MP0000470_abnormal_stomach_morphology0.50854611
109MP0000767_abnormal_smooth_muscle0.50331456
110MP0005535_abnormal_body_temperature0.49554889
111MP0003566_abnormal_cell_adhesion0.47513043
112MP0009840_abnormal_foam_cell0.47205926
113MP0005058_abnormal_lysosome_morphology0.46620174
114MP0000249_abnormal_blood_vessel0.46509822
115MP0005410_abnormal_fertilization0.45203958
116MP0005584_abnormal_enzyme/coenzyme_acti0.44754704
117MP0005319_abnormal_enzyme/_coenzyme0.44137053
118MP0000343_altered_response_to0.43751942
119MP0002019_abnormal_tumor_incidence0.41266078
120MP0001851_eye_inflammation0.40679846
121MP0001663_abnormal_digestive_system0.40386667
122MP0005174_abnormal_tail_pigmentation0.39986966
123MP0009765_abnormal_xenobiotic_induced0.39037107
124MP0009115_abnormal_fat_cell0.38150298
125MP0003646_muscle_fatigue0.37887082
126MP0005390_skeleton_phenotype0.36134991
127MP0002928_abnormal_bile_duct0.35853714

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)6.16048465
2Abnormality of glycolipid metabolism (HP:0010969)5.86714618
3Abnormality of liposaccharide metabolism (HP:0010968)5.86714618
4Abnormality of glycosphingolipid metabolism (HP:0004343)5.86714618
5Recurrent bacterial skin infections (HP:0005406)5.62007574
6Increased IgM level (HP:0003496)5.41724015
7Recurrent abscess formation (HP:0002722)5.35496823
8Recurrent fungal infections (HP:0002841)5.13155587
9Recurrent cutaneous fungal infections (HP:0011370)5.04959564
10Chronic mucocutaneous candidiasis (HP:0002728)5.04959564
11Chronic otitis media (HP:0000389)4.92825336
12Agammaglobulinemia (HP:0004432)4.90314433
13Abnormal delayed hypersensitivity skin test (HP:0002963)4.71990043
14Vacuolated lymphocytes (HP:0001922)4.59216573
15Autoimmune thrombocytopenia (HP:0001973)4.56324305
16Vasculitis (HP:0002633)4.53912430
17Recurrent skin infections (HP:0001581)4.52513557
18Dysostosis multiplex (HP:0000943)4.51499463
19Mediastinal lymphadenopathy (HP:0100721)4.49636093
20Recurrent viral infections (HP:0004429)4.45650962
21Optic neuritis (HP:0100653)4.24201472
22Retrobulbar optic neuritis (HP:0100654)4.24201472
23Myositis (HP:0100614)4.23850135
24Nasal polyposis (HP:0100582)4.22856128
25Elevated erythrocyte sedimentation rate (HP:0003565)4.19935038
26Recurrent bronchitis (HP:0002837)4.16798512
27Recurrent gram-negative bacterial infections (HP:0005420)4.10664020
28Loss of speech (HP:0002371)4.04092686
29Hypergammaglobulinemia (HP:0010702)3.94102404
30Gastrointestinal infarctions (HP:0005244)3.93046801
31Increased cerebral lipofuscin (HP:0011813)3.91682921
32Colitis (HP:0002583)3.87660045
33Gastrointestinal stroma tumor (HP:0100723)3.84887154
34Systemic lupus erythematosus (HP:0002725)3.82990619
35Orchitis (HP:0100796)3.82106574
36Abnormality of macrophages (HP:0004311)3.80141093
37Cellulitis (HP:0100658)3.70666645
38Chronic sinusitis (HP:0011109)3.65592385
39Keratoconjunctivitis (HP:0001096)3.64345376
40Increased IgE level (HP:0003212)3.56191187
41Interstitial pulmonary disease (HP:0006530)3.51493779
42Abnormality of polysaccharide metabolism (HP:0011012)3.48634461
43Abnormality of glycosaminoglycan metabolism (HP:0004371)3.48634461
44Abnormality of mucopolysaccharide metabolism (HP:0011020)3.48634461
45Abnormality of the nasal mucosa (HP:0000433)3.45859526
46Urinary glycosaminoglycan excretion (HP:0003541)3.36962595
47Mucopolysacchariduria (HP:0008155)3.36962595
48Pulmonary infiltrates (HP:0002113)3.35841071
49Inflammation of the large intestine (HP:0002037)3.34715677
50Meningitis (HP:0001287)3.32897784
51Increased neuronal autofluorescent lipopigment (HP:0002074)3.32261624
52Gingivitis (HP:0000230)3.25904489
53Thrombocytosis (HP:0001894)3.24384497
54Recurrent pneumonia (HP:0006532)3.20325007
55Gastrointestinal inflammation (HP:0004386)3.17176783
56Recurrent lower respiratory tract infections (HP:0002783)3.16186974
57Emphysema (HP:0002097)3.14337275
58Panhypogammaglobulinemia (HP:0003139)3.11353207
59Tetraparesis (HP:0002273)3.09385694
60Disinhibition (HP:0000734)3.02618025
61Abnormality of cells of the lymphoid lineage (HP:0012140)2.98815822
62Arterial thrombosis (HP:0004420)2.98279491
63Eosinophilia (HP:0001880)2.96932122
64Combined immunodeficiency (HP:0005387)2.94401808
65Basal ganglia calcification (HP:0002135)2.93578020
66Recurrent sinusitis (HP:0011108)2.91965365
67IgA deficiency (HP:0002720)2.86069574
68Mutism (HP:0002300)2.84181469
69Chronic obstructive pulmonary disease (HP:0006510)2.80858226
70Obstructive lung disease (HP:0006536)2.80858226
71Abnormality of T cell physiology (HP:0011840)2.80462640
72Abnormality of T cell number (HP:0011839)2.75506012
73Lymphopenia (HP:0001888)2.72383445
74Periodontitis (HP:0000704)2.67246689
75Autoimmune hemolytic anemia (HP:0001890)2.65651879
76Severe combined immunodeficiency (HP:0004430)2.64185317
77Granulocytopenia (HP:0001913)2.63949210
78Keratoconjunctivitis sicca (HP:0001097)2.58298975
79Urticaria (HP:0001025)2.57012626
80Osteomyelitis (HP:0002754)2.56012852
81Encephalitis (HP:0002383)2.55185287
82Gangrene (HP:0100758)2.54993829
83Leukocytosis (HP:0001974)2.53264314
84Porencephaly (HP:0002132)2.52509455
85Fatigue (HP:0012378)2.51908887
86Abnormality of proline metabolism (HP:0010907)2.50645981
87Hydroxyprolinuria (HP:0003080)2.50645981
88Bronchitis (HP:0012387)2.50138197
89Asymmetric septal hypertrophy (HP:0001670)2.49007950
90Abnormality of T cells (HP:0002843)2.46201929
91IgG deficiency (HP:0004315)2.45520962
92Hemoptysis (HP:0002105)2.42589055
93Hypochromic anemia (HP:0001931)2.41630765
94Hepatosplenomegaly (HP:0001433)2.41267915
95Gingival bleeding (HP:0000225)2.40046576
96Pustule (HP:0200039)2.39113041
97Chronic diarrhea (HP:0002028)2.35259796
98Polyneuropathy (HP:0001271)2.34447128
99Chest pain (HP:0100749)2.34379782
100Glomerulonephritis (HP:0000099)2.32948668
101Myocardial infarction (HP:0001658)2.32509482
102Abnormality of eosinophils (HP:0001879)2.31802218
103Abnormality of the fingertips (HP:0001211)2.29176168
104IgM deficiency (HP:0002850)2.28504576
105Progressive neurologic deterioration (HP:0002344)2.28322095
106Persistence of primary teeth (HP:0006335)2.26499894
107Arthralgia (HP:0002829)2.26496323
108Skin ulcer (HP:0200042)2.19588934
109Increased serum ferritin (HP:0003281)2.19266224
110Abnormality of B cell number (HP:0010975)2.18474022
111Amaurosis fugax (HP:0100576)2.18315823
112Papilloma (HP:0012740)2.17535380
113Verrucae (HP:0200043)2.17535380
114Abnormality of the pleura (HP:0002103)2.16963810
115B lymphocytopenia (HP:0010976)2.15075898
116Purpura (HP:0000979)2.14884673
117Pulmonary fibrosis (HP:0002206)2.14146416
118Sepsis (HP:0100806)2.13474390
119Hypertensive crisis (HP:0100735)2.12212258
120Acrocyanosis (HP:0001063)2.11944453
121Metaphyseal irregularity (HP:0003025)2.11730135
122Increased density of long bones (HP:0006392)2.10797811
123Viral hepatitis (HP:0006562)2.10479181
124Hematochezia (HP:0002573)2.10333947
125Petechiae (HP:0000967)2.09837671
126Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.06673572
127Thyroiditis (HP:0100646)2.04005917
128Neurofibrillary tangles (HP:0002185)2.03161317
129Nuclear cataract (HP:0100018)2.03152096
130Apathy (HP:0000741)2.02808281
131Anorexia (HP:0002039)2.01410783
132Restrictive lung disease (HP:0002091)2.01057342
133Stomatitis (HP:0010280)2.00983360
134Abnormality of the prostate (HP:0008775)1.98094122
135Premature loss of primary teeth (HP:0006323)1.97427993
136Neutropenia (HP:0001875)1.97418815
137Joint swelling (HP:0001386)1.95896859
138Osteolytic defects of the hand bones (HP:0009699)1.94113952
139Osteolytic defects of the phalanges of the hand (HP:0009771)1.94113952
140Leukopenia (HP:0001882)1.92872318
141Keratitis (HP:0000491)1.89032960
142T lymphocytopenia (HP:0005403)1.88971325

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K146.60787315
2TBK13.76941831
3TYK23.68691523
4MAP3K133.65448145
5JAK33.62815002
6IKBKB3.47482995
7RIPK43.32091961
8MAP4K12.96130585
9NME22.85739210
10IRAK42.85343715
11IKBKE2.80875773
12CHUK2.75896094
13GRK72.61015468
14JAK12.45083265
15BLK2.37626104
16TESK22.33739208
17EPHB12.28520141
18EPHA32.23076479
19DDR22.02305757
20SYK1.84951605
21FGFR41.84497866
22TLK11.80649707
23TAOK21.80597665
24IRAK31.79966718
25PRPF4B1.78968254
26SIK31.77057066
27CSF1R1.69508697
28PIM21.54713728
29BMPR21.53473619
30KIT1.46251402
31MAP2K21.37720971
32BTK1.36988595
33MST41.29845195
34FGFR31.29192427
35BCKDK1.26989095
36TGFBR21.24435649
37JAK21.22050118
38ADRBK21.20048087
39MAP3K111.18095311
40IRAK11.12249290
41PKN11.09726499
42BCR1.09346390
43PIM11.07876927
44CSK1.07455570
45SIK21.06744677
46NLK1.00587859
47PBK0.99338741
48ARAF0.97798204
49TESK10.96345347
50NEK90.96331626
51ERN10.92069265
52HCK0.91133386
53LCK0.87681175
54LRRK20.87510973
55LYN0.87305191
56TAOK10.86189243
57PTK60.84986241
58PRKCQ0.84537256
59DYRK1B0.81317300
60BMX0.81168411
61RIPK10.80147360
62ZAP700.79167776
63RPS6KA40.70500459
64STK40.69034867
65STK100.67459519
66DAPK30.67350050
67EIF2AK20.67220129
68MARK30.66365290
69MAP3K100.65942708
70MAP3K30.63257797
71MAPKAPK20.63039721
72FGR0.62784741
73ACVR1B0.62653562
74PRKCD0.61433844
75GRK60.57287364
76SIK10.57181593
77CDK120.56755609
78TEC0.56403469
79MAPK70.56120324
80CDK40.54334958
81IRAK20.54316132
82MAPK110.53538674
83MATK0.53425491
84STK240.52533106
85MAPK40.51333593
86TXK0.51264602
87ALK0.50643474
88ABL10.49641454
89KDR0.48053441
90ZAK0.47369734
91MAP3K50.46863905
92EGFR0.43306054
93BMPR1B0.42482865
94RPS6KA10.42090474
95PRKAA20.40131844
96YES10.39629541
97RPS6KA50.37637627
98STK30.36943786
99TYRO30.35968983
100TNK20.33892861
101SMG10.32338745
102MAP3K80.32225507
103RPS6KC10.31363967
104RPS6KL10.31363967
105MAP2K30.29867460
106VRK10.29689392
107RPS6KA20.29576892
108MAP3K90.29548217
109CDC42BPA0.28279388
110PTK2B0.26728054
111MAP3K10.26433959
112RPS6KA60.26306624
113FES0.25309970
114CDK60.25052940
115FYN0.24995388
116ITK0.24297055
117MOS0.24167425
118PDK10.23865103
119CAMKK20.23754698
120DYRK30.22706804
121INSR0.22652550
122PRKCZ0.22590995
123GRK10.19681364
124HIPK20.17742050
125MAP2K60.17418856
126ABL20.15765692
127FLT30.15568765
128PRKCE0.14979110
129CLK10.14331050
130TAOK30.14293554
131SRC0.14110261
132ERBB30.13778898
133WNK10.11216489
134MAPK30.11021531
135AKT10.10548766
136SGK10.10243482

Predicted pathways (KEGG)

RankGene SetZ-score
1Allograft rejection_Homo sapiens_hsa053304.19150148
2NF-kappa B signaling pathway_Homo sapiens_hsa040643.42070920
3Intestinal immune network for IgA production_Homo sapiens_hsa046723.37211178
4Graft-versus-host disease_Homo sapiens_hsa053323.30232084
5Leishmaniasis_Homo sapiens_hsa051402.94144607
6Primary immunodeficiency_Homo sapiens_hsa053402.89628533
7Toll-like receptor signaling pathway_Homo sapiens_hsa046202.64887744
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.55439349
9Autoimmune thyroid disease_Homo sapiens_hsa053202.54144541
10Measles_Homo sapiens_hsa051622.48111575
11Type I diabetes mellitus_Homo sapiens_hsa049402.45255854
12RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.43275471
13Other glycan degradation_Homo sapiens_hsa005112.42673974
14Antigen processing and presentation_Homo sapiens_hsa046122.40387856
15B cell receptor signaling pathway_Homo sapiens_hsa046622.36180748
16NOD-like receptor signaling pathway_Homo sapiens_hsa046212.30582651
17Osteoclast differentiation_Homo sapiens_hsa043802.23333295
18TNF signaling pathway_Homo sapiens_hsa046682.10439563
19Influenza A_Homo sapiens_hsa051642.00715372
20Toxoplasmosis_Homo sapiens_hsa051451.99896744
21Herpes simplex infection_Homo sapiens_hsa051681.95543363
22Legionellosis_Homo sapiens_hsa051341.91324816
23African trypanosomiasis_Homo sapiens_hsa051431.86520293
24Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.86179881
25Systemic lupus erythematosus_Homo sapiens_hsa053221.79285708
26Chemokine signaling pathway_Homo sapiens_hsa040621.75636550
27Jak-STAT signaling pathway_Homo sapiens_hsa046301.73536681
28Apoptosis_Homo sapiens_hsa042101.69621792
29Asthma_Homo sapiens_hsa053101.69408164
30Tuberculosis_Homo sapiens_hsa051521.63731194
31Pertussis_Homo sapiens_hsa051331.63225200
32Viral myocarditis_Homo sapiens_hsa054161.60583282
33Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.54506071
34Malaria_Homo sapiens_hsa051441.45332887
35Rheumatoid arthritis_Homo sapiens_hsa053231.43071313
36Shigellosis_Homo sapiens_hsa051311.30562992
37Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.25329999
38Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.14887653
39Hepatitis B_Homo sapiens_hsa051611.14837015
40Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.11891917
41Prolactin signaling pathway_Homo sapiens_hsa049171.11018698
42T cell receptor signaling pathway_Homo sapiens_hsa046601.10791151
43Acute myeloid leukemia_Homo sapiens_hsa052211.09694387
44Epstein-Barr virus infection_Homo sapiens_hsa051691.09348938
45Salmonella infection_Homo sapiens_hsa051321.06152875
46Hematopoietic cell lineage_Homo sapiens_hsa046401.05486096
47Hepatitis C_Homo sapiens_hsa051601.01799434
48Staphylococcus aureus infection_Homo sapiens_hsa051500.91279483
49AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.86733339
50Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.85864898
51Small cell lung cancer_Homo sapiens_hsa052220.85863890
52Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.76746148
53Viral carcinogenesis_Homo sapiens_hsa052030.76655746
54Chronic myeloid leukemia_Homo sapiens_hsa052200.76242843
55Leukocyte transendothelial migration_Homo sapiens_hsa046700.74251899
56Transcriptional misregulation in cancer_Homo sapiens_hsa052020.71350986
57Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.70990416
58Adipocytokine signaling pathway_Homo sapiens_hsa049200.70847124
59HTLV-I infection_Homo sapiens_hsa051660.67363418
60Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.63569355
61Neurotrophin signaling pathway_Homo sapiens_hsa047220.60931416
62Pancreatic cancer_Homo sapiens_hsa052120.57359104
63Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.56694684
64Collecting duct acid secretion_Homo sapiens_hsa049660.54326891
65Phagosome_Homo sapiens_hsa041450.53545353
66p53 signaling pathway_Homo sapiens_hsa041150.53318258
67Sphingolipid metabolism_Homo sapiens_hsa006000.51436701
68Bladder cancer_Homo sapiens_hsa052190.50609345
69Amoebiasis_Homo sapiens_hsa051460.50427433
70Sulfur metabolism_Homo sapiens_hsa009200.49154301
71Proteasome_Homo sapiens_hsa030500.48077317
72MAPK signaling pathway_Homo sapiens_hsa040100.43663500
73Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.41454464
74Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.39287675
75Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38065316
76Lysosome_Homo sapiens_hsa041420.37217297
77Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37058862
78Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.36933042
79HIF-1 signaling pathway_Homo sapiens_hsa040660.34043542
80SNARE interactions in vesicular transport_Homo sapiens_hsa041300.32576132
81VEGF signaling pathway_Homo sapiens_hsa043700.32307619
82Insulin resistance_Homo sapiens_hsa049310.31852265
83MicroRNAs in cancer_Homo sapiens_hsa052060.31189697
84Dorso-ventral axis formation_Homo sapiens_hsa043200.31160840
85Type II diabetes mellitus_Homo sapiens_hsa049300.30984185
86Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.30233597
87Alcoholism_Homo sapiens_hsa050340.29500556
88Platelet activation_Homo sapiens_hsa046110.28481229
89Galactose metabolism_Homo sapiens_hsa000520.27868232
90Vibrio cholerae infection_Homo sapiens_hsa051100.24729434
91Prion diseases_Homo sapiens_hsa050200.24130860
92FoxO signaling pathway_Homo sapiens_hsa040680.23511985
93Regulation of actin cytoskeleton_Homo sapiens_hsa048100.23055121
94Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.22821546
95Notch signaling pathway_Homo sapiens_hsa043300.22150349
96Proteoglycans in cancer_Homo sapiens_hsa052050.21972556
97Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.21250047
98Pathways in cancer_Homo sapiens_hsa052000.20439146
99Complement and coagulation cascades_Homo sapiens_hsa046100.19361814
100Fructose and mannose metabolism_Homo sapiens_hsa000510.17735657
101Non-small cell lung cancer_Homo sapiens_hsa052230.16080720
102Endocytosis_Homo sapiens_hsa041440.15433131
103Prostate cancer_Homo sapiens_hsa052150.14899516
104Renin-angiotensin system_Homo sapiens_hsa046140.14449631
105Mineral absorption_Homo sapiens_hsa049780.13347267
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.11417197
107Glycosaminoglycan degradation_Homo sapiens_hsa005310.11013834
108* Tryptophan metabolism_Homo sapiens_hsa003800.10911243
109ErbB signaling pathway_Homo sapiens_hsa040120.08822018
110ABC transporters_Homo sapiens_hsa020100.08036229
111Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.07658378
112Ras signaling pathway_Homo sapiens_hsa040140.07601984
113Phosphatidylinositol signaling system_Homo sapiens_hsa040700.06900383
114Adherens junction_Homo sapiens_hsa045200.06883404
115Pentose phosphate pathway_Homo sapiens_hsa000300.06576177
116Inositol phosphate metabolism_Homo sapiens_hsa005620.05189205
117Caffeine metabolism_Homo sapiens_hsa002320.04991106
118Thyroid hormone signaling pathway_Homo sapiens_hsa049190.03113491
119Carbohydrate digestion and absorption_Homo sapiens_hsa049730.01762204
120Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.00389760
121PPAR signaling pathway_Homo sapiens_hsa03320-0.0231780
122Primary bile acid biosynthesis_Homo sapiens_hsa00120-0.0142535
123Cyanoamino acid metabolism_Homo sapiens_hsa00460-0.0065088

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