Rank | Gene Set | Z-score |
---|---|---|
1 | COPI coating of Golgi vesicle (GO:0048205) | 4.65087392 |
2 | Golgi transport vesicle coating (GO:0048200) | 4.65087392 |
3 | protein maturation by protein folding (GO:0022417) | 4.50630475 |
4 | * extracellular fibril organization (GO:0043206) | 4.11398554 |
5 | thrombin receptor signaling pathway (GO:0070493) | 4.07251176 |
6 | protein neddylation (GO:0045116) | 4.00063765 |
7 | positive regulation of receptor recycling (GO:0001921) | 3.78760306 |
8 | chondrocyte proliferation (GO:0035988) | 3.78258083 |
9 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 3.66556364 |
10 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.56624373 |
11 | positive regulation of Rho protein signal transduction (GO:0035025) | 3.53755516 |
12 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.50721986 |
13 | barbed-end actin filament capping (GO:0051016) | 3.48739605 |
14 | negative regulation of phagocytosis (GO:0050765) | 3.48556470 |
15 | protein heterotrimerization (GO:0070208) | 3.47021196 |
16 | collagen fibril organization (GO:0030199) | 3.42197949 |
17 | positive regulation of macrophage differentiation (GO:0045651) | 3.41242089 |
18 | regulation of platelet aggregation (GO:0090330) | 3.39463574 |
19 | protein retention in ER lumen (GO:0006621) | 3.39126459 |
20 | negative regulation of fatty acid transport (GO:2000192) | 3.32716178 |
21 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 3.32220973 |
22 | positive regulation of actin filament depolymerization (GO:0030836) | 3.26498367 |
23 | endodermal cell differentiation (GO:0035987) | 3.23715835 |
24 | pinocytosis (GO:0006907) | 3.22812062 |
25 | negative regulation of platelet activation (GO:0010544) | 3.20385254 |
26 | regulation of platelet activation (GO:0010543) | 3.17000079 |
27 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.13213982 |
28 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.13129804 |
29 | basement membrane organization (GO:0071711) | 3.11078356 |
30 | adenosine receptor signaling pathway (GO:0001973) | 3.08740146 |
31 | type B pancreatic cell proliferation (GO:0044342) | 3.06724224 |
32 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.05659522 |
33 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.05659522 |
34 | keratan sulfate catabolic process (GO:0042340) | 3.04183884 |
35 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.03676164 |
36 | * platelet aggregation (GO:0070527) | 3.02032197 |
37 | cell adhesion mediated by integrin (GO:0033627) | 3.01917011 |
38 | epithelial cell-cell adhesion (GO:0090136) | 3.01299877 |
39 | regulation of homotypic cell-cell adhesion (GO:0034110) | 2.97916011 |
40 | leukocyte migration involved in inflammatory response (GO:0002523) | 2.94996864 |
41 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 2.93431535 |
42 | membrane invagination (GO:0010324) | 2.93126092 |
43 | negative regulation of protein localization to cell surface (GO:2000009) | 2.92745997 |
44 | positive regulation of endothelial cell differentiation (GO:0045603) | 2.92169273 |
45 | negative regulation of protein localization to plasma membrane (GO:1903077) | 2.89722042 |
46 | regulation of receptor recycling (GO:0001919) | 2.89367143 |
47 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.86262214 |
48 | dermatan sulfate metabolic process (GO:0030205) | 2.86219731 |
49 | protein localization to endosome (GO:0036010) | 2.86135838 |
50 | mesodermal cell differentiation (GO:0048333) | 2.85521970 |
51 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.79935065 |
52 | beta-amyloid metabolic process (GO:0050435) | 2.77507525 |
53 | cell proliferation involved in metanephros development (GO:0072203) | 2.77286220 |
54 | sequestering of extracellular ligand from receptor (GO:0035581) | 2.75890857 |
55 | negative regulation of stress fiber assembly (GO:0051497) | 2.74706588 |
56 | dermatan sulfate biosynthetic process (GO:0030208) | 2.74699512 |
57 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.74615049 |
58 | actin-myosin filament sliding (GO:0033275) | 2.74239605 |
59 | muscle filament sliding (GO:0030049) | 2.74239605 |
60 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) | 2.72652580 |
61 | positive regulation of epithelial to mesenchymal transition (GO:0010718) | 2.72363718 |
62 | fibrinolysis (GO:0042730) | 2.72082311 |
63 | regulation of integrin activation (GO:0033623) | 2.71902162 |
64 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.71474189 |
65 | wound healing, spreading of epidermal cells (GO:0035313) | 2.70635739 |
66 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.69501333 |
67 | angiogenesis involved in wound healing (GO:0060055) | 2.69416283 |
68 | response to interferon-alpha (GO:0035455) | 2.67725882 |
69 | sequestering of actin monomers (GO:0042989) | 2.67421362 |
70 | lipoxygenase pathway (GO:0019372) | 2.65607205 |
71 | negative regulation of release of cytochrome c from mitochondria (GO:0090201) | 2.64671249 |
72 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.64325656 |
73 | skin morphogenesis (GO:0043589) | 2.64155484 |
74 | platelet activation (GO:0030168) | 2.63648663 |
75 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.63610106 |
76 | neutrophil activation involved in immune response (GO:0002283) | 2.62675054 |
77 | response to interferon-beta (GO:0035456) | 2.62560150 |
78 | collagen metabolic process (GO:0032963) | 2.61835790 |
79 | response to gravity (GO:0009629) | 2.61783895 |
80 | positive regulation of interleukin-8 secretion (GO:2000484) | 2.61411062 |
81 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.60795548 |
82 | membrane raft organization (GO:0031579) | 2.60773740 |
83 | hyaluronan catabolic process (GO:0030214) | 2.60280601 |
84 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.60043321 |
85 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.59826701 |
86 | apoptotic cell clearance (GO:0043277) | 2.59388068 |
87 | peptide catabolic process (GO:0043171) | 2.58809981 |
88 | signal peptide processing (GO:0006465) | 2.57711538 |
89 | wound healing, spreading of cells (GO:0044319) | 2.56711664 |
90 | endothelium development (GO:0003158) | 2.55833296 |
91 | regulation of protein heterodimerization activity (GO:0043497) | 2.55383588 |
92 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.54487848 |
93 | blood coagulation, intrinsic pathway (GO:0007597) | 2.54181163 |
94 | polyamine biosynthetic process (GO:0006596) | 2.53976695 |
95 | positive regulation of hemostasis (GO:1900048) | 2.53267210 |
96 | positive regulation of blood coagulation (GO:0030194) | 2.53267210 |
97 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 2.52078311 |
98 | UV protection (GO:0009650) | 2.47368467 |
99 | sarcomere organization (GO:0045214) | 2.46929164 |
100 | collagen catabolic process (GO:0030574) | 2.46868677 |
101 | endosome to pigment granule transport (GO:0043485) | 2.45899024 |
102 | endosome to melanosome transport (GO:0035646) | 2.45899024 |
103 | negative regulation of thymocyte apoptotic process (GO:0070244) | 2.45017610 |
104 | positive regulation of coagulation (GO:0050820) | 2.44742998 |
105 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 2.44022245 |
106 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 2.43029472 |
107 | cell migration involved in heart development (GO:0060973) | 2.42946854 |
108 | heart process (GO:0003015) | 2.42833752 |
109 | heart contraction (GO:0060047) | 2.42833752 |
110 | * fibril organization (GO:0097435) | 2.42493821 |
111 | endothelial tube morphogenesis (GO:0061154) | 2.42066713 |
112 | morphogenesis of an endothelium (GO:0003159) | 2.42066713 |
113 | positive regulation of substrate adhesion-dependent cell spreading (GO:1900026) | 2.39721056 |
114 | cyclooxygenase pathway (GO:0019371) | 2.39717648 |
115 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.39647235 |
116 | positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511) | 2.39321898 |
117 | protein localization to cell surface (GO:0034394) | 2.38324630 |
118 | muscle cell migration (GO:0014812) | 2.36903689 |
119 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.36835701 |
120 | stress fiber assembly (GO:0043149) | 2.36473140 |
121 | phagocytosis, engulfment (GO:0006911) | 2.35205830 |
122 | neutrophil activation (GO:0042119) | 2.35049468 |
123 | protein targeting to plasma membrane (GO:0072661) | 2.33384864 |
124 | regulation of macrophage cytokine production (GO:0010935) | 2.33143650 |
125 | regulation of tight junction assembly (GO:2000810) | 2.32294605 |
126 | actin-mediated cell contraction (GO:0070252) | 2.32227116 |
127 | hypotonic response (GO:0006971) | 2.31956122 |
128 | T cell apoptotic process (GO:0070231) | 2.31158835 |
129 | cortical actin cytoskeleton organization (GO:0030866) | 2.31009324 |
130 | negative regulation of coagulation (GO:0050819) | 2.30993361 |
131 | regulation of metalloenzyme activity (GO:0048552) | 2.30824085 |
132 | blood vessel maturation (GO:0001955) | 2.30498066 |
133 | extracellular matrix disassembly (GO:0022617) | 2.30093268 |
134 | regulation of coagulation (GO:0050818) | 2.29871020 |
135 | regulation of mononuclear cell migration (GO:0071675) | 2.29315350 |
136 | cellular response to vitamin (GO:0071295) | 2.29028714 |
137 | regulation of hemostasis (GO:1900046) | 2.28628577 |
138 | regulation of blood coagulation (GO:0030193) | 2.28628577 |
139 | actin filament depolymerization (GO:0030042) | 2.27892008 |
140 | renal filtration (GO:0097205) | 2.27459078 |
141 | cellular response to zinc ion (GO:0071294) | 2.26152840 |
142 | purine-containing compound salvage (GO:0043101) | 2.25518655 |
143 | cell proliferation involved in kidney development (GO:0072111) | 2.24972632 |
144 | atrioventricular valve morphogenesis (GO:0003181) | 2.23289612 |
145 | multicellular organismal catabolic process (GO:0044243) | 2.23134724 |
146 | cardiac myofibril assembly (GO:0055003) | 2.23097756 |
147 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.23059933 |
148 | phagocytosis, recognition (GO:0006910) | 2.21704653 |
149 | endocardial cushion development (GO:0003197) | 2.21670198 |
150 | definitive hemopoiesis (GO:0060216) | 2.21533954 |
151 | multicellular organismal metabolic process (GO:0044236) | 2.21031184 |
152 | platelet degranulation (GO:0002576) | 2.20638954 |
153 | glomerular basement membrane development (GO:0032836) | 2.20552628 |
154 | sequestering of metal ion (GO:0051238) | 2.19186587 |
155 | * substrate adhesion-dependent cell spreading (GO:0034446) | 2.19085557 |
156 | substrate-dependent cell migration (GO:0006929) | 2.18575470 |
157 | positive regulation of lamellipodium assembly (GO:0010592) | 2.18375273 |
158 | glomerular filtration (GO:0003094) | 2.15685033 |
159 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.15018432 |
160 | response to fluid shear stress (GO:0034405) | 2.14225924 |
161 | platelet dense granule organization (GO:0060155) | 2.13992703 |
162 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.13693944 |
163 | * homotypic cell-cell adhesion (GO:0034109) | 2.13255632 |
164 | positive regulation of lamellipodium organization (GO:1902745) | 2.10777102 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.47845246 |
2 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 3.46732342 |
3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.05619459 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.97223029 |
5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.69192328 |
6 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.68820586 |
7 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.65521894 |
8 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.54440859 |
9 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.54170160 |
10 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.40106235 |
11 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.23084192 |
12 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.14959363 |
13 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.14460705 |
14 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.11790879 |
15 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 2.11111239 |
16 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.10790798 |
17 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.10631133 |
18 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.06732968 |
19 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.02349436 |
20 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.99564630 |
21 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.97564335 |
22 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.96723419 |
23 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.95602084 |
24 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.95222371 |
25 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.93948951 |
26 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.88234566 |
27 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.82748626 |
28 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.80416673 |
29 | GATA1_22025678_ChIP-Seq_K562_Human | 1.74838678 |
30 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.73765526 |
31 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.68924849 |
32 | * CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.68096559 |
33 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.67875545 |
34 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.67269375 |
35 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.66593089 |
36 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.66436495 |
37 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.61626030 |
38 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.61388226 |
39 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.61124619 |
40 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.60998063 |
41 | * ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.58282937 |
42 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.57724088 |
43 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.56970973 |
44 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.56061282 |
45 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.55607829 |
46 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55237097 |
47 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.53554212 |
48 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.52724191 |
49 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.52618647 |
50 | MAF_26560356_Chip-Seq_TH1_Human | 1.52271042 |
51 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.49963135 |
52 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.46876608 |
53 | MYC_22102868_ChIP-Seq_BL_Human | 1.44978442 |
54 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.44308303 |
55 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.43375217 |
56 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.42114076 |
57 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.42049074 |
58 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.41493308 |
59 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.38195459 |
60 | * SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.36123239 |
61 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.34959103 |
62 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.33649657 |
63 | MYB_26560356_Chip-Seq_TH2_Human | 1.32789002 |
64 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.32419802 |
65 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29457063 |
66 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.27975797 |
67 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.27533567 |
68 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.24003964 |
69 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22238198 |
70 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.21835812 |
71 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.21831528 |
72 | GATA1_19941826_ChIP-Seq_K562_Human | 1.20859003 |
73 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.20747373 |
74 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.20643838 |
75 | UTX_26944678_Chip-Seq_JUKART_Human | 1.19973088 |
76 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.19745353 |
77 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.19249180 |
78 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.19014871 |
79 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.19014871 |
80 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.18044523 |
81 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.17293318 |
82 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.16665499 |
83 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.15703696 |
84 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.14207065 |
85 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.13941074 |
86 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.13457998 |
87 | SPI1_23127762_ChIP-Seq_K562_Human | 1.13436129 |
88 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.13259789 |
89 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.11115135 |
90 | CJUN_26792858_Chip-Seq_BT549_Human | 1.09529869 |
91 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.09002185 |
92 | MYB_26560356_Chip-Seq_TH1_Human | 1.08955396 |
93 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.08887873 |
94 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.08704294 |
95 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.07662659 |
96 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.07374726 |
97 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.07037166 |
98 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.05743328 |
99 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.04795078 |
100 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.04627023 |
101 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.04425511 |
102 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.04411302 |
103 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.03683060 |
104 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.03399490 |
105 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.03385668 |
106 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.03385668 |
107 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.03256009 |
108 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.03060700 |
109 | GATA2_19941826_ChIP-Seq_K562_Human | 1.02795734 |
110 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.02291622 |
111 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.02276105 |
112 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.02233695 |
113 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.02013664 |
114 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01928120 |
115 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.01741324 |
116 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.01581661 |
117 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.01581661 |
118 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 1.01007333 |
119 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.00696579 |
120 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.00281203 |
121 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.99389480 |
122 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.97712740 |
123 | ATF3_27146783_Chip-Seq_COLON_Human | 0.97649320 |
124 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97107957 |
125 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.95934706 |
126 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.94890598 |
127 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.94666412 |
128 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.94132493 |
129 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.93647720 |
130 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.93395089 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 5.51777981 |
2 | MP0003279_aneurysm | 3.63123188 |
3 | MP0006054_spinal_hemorrhage | 3.47501967 |
4 | MP0005503_abnormal_tendon_morphology | 3.22086442 |
5 | MP0005275_abnormal_skin_tensile | 3.03780246 |
6 | MP0003705_abnormal_hypodermis_morpholog | 2.48805997 |
7 | MP0008004_abnormal_stomach_pH | 2.45935170 |
8 | MP0001958_emphysema | 2.35543936 |
9 | * MP0003566_abnormal_cell_adhesion | 2.28796523 |
10 | MP0009840_abnormal_foam_cell | 2.19697291 |
11 | MP0005257_abnormal_intraocular_pressure | 2.13557177 |
12 | MP0010368_abnormal_lymphatic_system | 2.10059745 |
13 | MP0003191_abnormal_cellular_cholesterol | 2.05842238 |
14 | MP0009384_cardiac_valve_regurgitation | 1.96730416 |
15 | MP0005023_abnormal_wound_healing | 1.90486316 |
16 | MP0004084_abnormal_cardiac_muscle | 1.78635408 |
17 | * MP0004272_abnormal_basement_membrane | 1.73412379 |
18 | MP0005165_increased_susceptibility_to | 1.68776806 |
19 | MP0001835_abnormal_antigen_presentation | 1.68674009 |
20 | MP0005058_abnormal_lysosome_morphology | 1.66436061 |
21 | MP0000343_altered_response_to | 1.64469375 |
22 | MP0001849_ear_inflammation | 1.62635180 |
23 | MP0000685_abnormal_immune_system | 1.59775781 |
24 | MP0000767_abnormal_smooth_muscle | 1.58997753 |
25 | MP0008260_abnormal_autophagy | 1.57009055 |
26 | MP0002933_joint_inflammation | 1.47706611 |
27 | MP0001533_abnormal_skeleton_physiology | 1.46696926 |
28 | MP0001542_abnormal_bone_strength | 1.46254539 |
29 | MP0001879_abnormal_lymphatic_vessel | 1.45997146 |
30 | MP0000751_myopathy | 1.45484598 |
31 | MP0002396_abnormal_hematopoietic_system | 1.44536902 |
32 | MP0003091_abnormal_cell_migration | 1.43476967 |
33 | MP0002877_abnormal_melanocyte_morpholog | 1.41084002 |
34 | MP0000749_muscle_degeneration | 1.39728960 |
35 | MP0005508_abnormal_skeleton_morphology | 1.38846743 |
36 | MP0003436_decreased_susceptibility_to | 1.37239939 |
37 | MP0010352_gastrointestinal_tract_polyps | 1.35167433 |
38 | MP0000465_gastrointestinal_hemorrhage | 1.34511697 |
39 | MP0009785_altered_susceptibility_to | 1.34432899 |
40 | MP0002166_altered_tumor_susceptibility | 1.32234168 |
41 | MP0005390_skeleton_phenotype | 1.29886545 |
42 | MP0004808_abnormal_hematopoietic_stem | 1.29691944 |
43 | MP0000858_altered_metastatic_potential | 1.29292267 |
44 | MP0005595_abnormal_vascular_smooth | 1.25063083 |
45 | MP0005623_abnormal_meninges_morphology | 1.23537665 |
46 | MP0003075_altered_response_to | 1.22558952 |
47 | MP0002148_abnormal_hypersensitivity_rea | 1.20884182 |
48 | MP0002419_abnormal_innate_immunity | 1.19536088 |
49 | MP0003806_abnormal_nucleotide_metabolis | 1.17474353 |
50 | MP0010030_abnormal_orbit_morphology | 1.17361809 |
51 | MP0005464_abnormal_platelet_physiology | 1.16914077 |
52 | MP0003300_gastrointestinal_ulcer | 1.15556401 |
53 | MP0003828_pulmonary_edema | 1.15021748 |
54 | MP0005397_hematopoietic_system_phenotyp | 1.11982743 |
55 | MP0001545_abnormal_hematopoietic_system | 1.11982743 |
56 | MP0001243_abnormal_dermal_layer | 1.10044011 |
57 | MP0000733_abnormal_muscle_development | 1.06800264 |
58 | MP0002128_abnormal_blood_circulation | 1.06668943 |
59 | MP0008007_abnormal_cellular_replicative | 1.06572036 |
60 | MP0003724_increased_susceptibility_to | 1.06207800 |
61 | MP0010630_abnormal_cardiac_muscle | 1.05922621 |
62 | MP0005083_abnormal_biliary_tract | 1.05390168 |
63 | MP0002060_abnormal_skin_morphology | 1.05213195 |
64 | MP0003172_abnormal_lysosome_physiology | 1.04909435 |
65 | MP0000013_abnormal_adipose_tissue | 1.03216194 |
66 | MP0002998_abnormal_bone_remodeling | 1.02530742 |
67 | MP0002295_abnormal_pulmonary_circulatio | 1.02219815 |
68 | MP0002405_respiratory_system_inflammati | 1.01262334 |
69 | MP0008775_abnormal_heart_ventricle | 0.99895309 |
70 | MP0000230_abnormal_systemic_arterial | 0.99563262 |
71 | MP0001544_abnormal_cardiovascular_syste | 0.99334764 |
72 | MP0005385_cardiovascular_system_phenoty | 0.99334764 |
73 | MP0003795_abnormal_bone_structure | 0.97853063 |
74 | MP0002452_abnormal_antigen_presenting | 0.97665982 |
75 | MP0005000_abnormal_immune_tolerance | 0.97149863 |
76 | MP0005671_abnormal_response_to | 0.97119492 |
77 | MP0003448_altered_tumor_morphology | 0.96264250 |
78 | MP0005025_abnormal_response_to | 0.95505201 |
79 | MP0002972_abnormal_cardiac_muscle | 0.95422893 |
80 | MP0000249_abnormal_blood_vessel | 0.93677143 |
81 | MP0005330_cardiomyopathy | 0.93341559 |
82 | MP0001614_abnormal_blood_vessel | 0.92574501 |
83 | MP0002006_tumorigenesis | 0.92551187 |
84 | MP0005620_abnormal_muscle_contractility | 0.91577102 |
85 | MP0009053_abnormal_anal_canal | 0.91215054 |
86 | MP0009278_abnormal_bone_marrow | 0.90338350 |
87 | MP0009764_decreased_sensitivity_to | 0.90240481 |
88 | MP0003186_abnormal_redox_activity | 0.90066838 |
89 | MP0009333_abnormal_splenocyte_physiolog | 0.89939051 |
90 | MP0005164_abnormal_response_to | 0.89500477 |
91 | MP0003303_peritoneal_inflammation | 0.89480022 |
92 | MP0004087_abnormal_muscle_fiber | 0.89368625 |
93 | MP0006138_congestive_heart_failure | 0.88530913 |
94 | MP0001853_heart_inflammation | 0.87856550 |
95 | MP0005084_abnormal_gallbladder_morpholo | 0.87491230 |
96 | MP0005166_decreased_susceptibility_to | 0.86347174 |
97 | MP0005171_absent_coat_pigmentation | 0.85620700 |
98 | MP0009780_abnormal_chondrocyte_physiolo | 0.85228819 |
99 | MP0009763_increased_sensitivity_to | 0.85076612 |
100 | MP0002420_abnormal_adaptive_immunity | 0.84801045 |
101 | MP0001915_intracranial_hemorrhage | 0.83924877 |
102 | MP0001819_abnormal_immune_cell | 0.83052371 |
103 | MP0001851_eye_inflammation | 0.82964038 |
104 | MP0010155_abnormal_intestine_physiology | 0.82483432 |
105 | MP0005387_immune_system_phenotype | 0.82256771 |
106 | MP0001790_abnormal_immune_system | 0.82256771 |
107 | MP0003385_abnormal_body_wall | 0.80958955 |
108 | * MP0002113_abnormal_skeleton_development | 0.79911250 |
109 | MP0004883_abnormal_blood_vessel | 0.79798045 |
110 | MP0003950_abnormal_plasma_membrane | 0.79190593 |
111 | MP0000750_abnormal_muscle_regeneration | 0.78924900 |
112 | MP0004510_myositis | 0.77715947 |
113 | * MP0001175_abnormal_lung_morphology | 0.77230374 |
114 | MP0004036_abnormal_muscle_relaxation | 0.77140117 |
115 | MP0001348_abnormal_lacrimal_gland | 0.76870279 |
116 | MP0003943_abnormal_hepatobiliary_system | 0.76562789 |
117 | MP0004947_skin_inflammation | 0.76355208 |
118 | MP0006082_CNS_inflammation | 0.76240270 |
119 | MP0002398_abnormal_bone_marrow | 0.76006406 |
120 | MP0001845_abnormal_inflammatory_respons | 0.74981739 |
121 | MP0002089_abnormal_postnatal_growth/wei | 0.74508531 |
122 | MP0002896_abnormal_bone_mineralization | 0.74290899 |
123 | MP0002925_abnormal_cardiovascular_devel | 0.74290842 |
124 | MP0002723_abnormal_immune_serum | 0.73911732 |
125 | MP0003763_abnormal_thymus_physiology | 0.73827260 |
126 | MP0002132_abnormal_respiratory_system | 0.69727511 |
127 | MP0010386_abnormal_urinary_bladder | 0.69483893 |
128 | MP0005167_abnormal_blood-brain_barrier | 0.66310484 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protrusio acetabuli (HP:0003179) | 5.95512133 |
2 | Increased mean platelet volume (HP:0011877) | 5.43643503 |
3 | Menorrhagia (HP:0000132) | 5.34257282 |
4 | Abnormal platelet volume (HP:0011876) | 5.13616669 |
5 | Premature rupture of membranes (HP:0001788) | 4.85319749 |
6 | Prolonged bleeding time (HP:0003010) | 4.77965319 |
7 | Aortic dissection (HP:0002647) | 4.63259538 |
8 | Purpura (HP:0000979) | 4.55686486 |
9 | Aortic aneurysm (HP:0004942) | 4.41033285 |
10 | Cervical subluxation (HP:0003308) | 3.83933789 |
11 | Cerebral aneurysm (HP:0004944) | 3.73930195 |
12 | Epistaxis (HP:0000421) | 3.72161894 |
13 | Vertebral compression fractures (HP:0002953) | 3.70025868 |
14 | Ankle contracture (HP:0006466) | 3.36542693 |
15 | Biconcave vertebral bodies (HP:0004586) | 3.35513580 |
16 | Impaired platelet aggregation (HP:0003540) | 3.23893835 |
17 | Abnormal platelet function (HP:0011869) | 3.23893835 |
18 | Gingival bleeding (HP:0000225) | 3.13931344 |
19 | Hyperlipoproteinemia (HP:0010980) | 3.13739408 |
20 | Dilatation of the ascending aorta (HP:0005111) | 3.08860169 |
21 | Soft skin (HP:0000977) | 2.98176500 |
22 | Peritonitis (HP:0002586) | 2.98060017 |
23 | Beaking of vertebral bodies (HP:0004568) | 2.88886111 |
24 | Broad metatarsal (HP:0001783) | 2.86900073 |
25 | Shallow orbits (HP:0000586) | 2.82232762 |
26 | Distal lower limb muscle weakness (HP:0009053) | 2.79054194 |
27 | Nonimmune hydrops fetalis (HP:0001790) | 2.76733968 |
28 | Type 1 muscle fiber predominance (HP:0003803) | 2.74246232 |
29 | Blue sclerae (HP:0000592) | 2.72680164 |
30 | Myocardial infarction (HP:0001658) | 2.71000032 |
31 | Hepatosplenomegaly (HP:0001433) | 2.70300391 |
32 | Spondylolisthesis (HP:0003302) | 2.62447327 |
33 | Increased variability in muscle fiber diameter (HP:0003557) | 2.62034151 |
34 | Neonatal short-limb short stature (HP:0008921) | 2.61069250 |
35 | Abnormality of the acetabulum (HP:0003170) | 2.59431306 |
36 | Wormian bones (HP:0002645) | 2.58323707 |
37 | Distal lower limb amyotrophy (HP:0008944) | 2.58249190 |
38 | Vascular tortuosity (HP:0004948) | 2.55623052 |
39 | Abnormality of dentin (HP:0010299) | 2.52110694 |
40 | Osteolytic defects of the hand bones (HP:0009699) | 2.51083904 |
41 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.51083904 |
42 | Spinal rigidity (HP:0003306) | 2.49822005 |
43 | Bladder diverticulum (HP:0000015) | 2.46964562 |
44 | Spontaneous hematomas (HP:0007420) | 2.46336606 |
45 | Upper limb muscle weakness (HP:0003484) | 2.43619206 |
46 | Bruising susceptibility (HP:0000978) | 2.40051571 |
47 | Abnormality of macrophages (HP:0004311) | 2.39227441 |
48 | Atrophic scars (HP:0001075) | 2.36224927 |
49 | Broad face (HP:0000283) | 2.35389298 |
50 | Joint stiffness (HP:0001387) | 2.34047840 |
51 | Arterial tortuosity (HP:0005116) | 2.32070667 |
52 | Mitral stenosis (HP:0001718) | 2.30823996 |
53 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.22085272 |
54 | Abnormal gallbladder physiology (HP:0012438) | 2.21739919 |
55 | Cholecystitis (HP:0001082) | 2.21739919 |
56 | Fragile skin (HP:0001030) | 2.19974429 |
57 | Increased connective tissue (HP:0009025) | 2.18640060 |
58 | Vacuolated lymphocytes (HP:0001922) | 2.18522142 |
59 | Abnormal pupillary function (HP:0007686) | 2.17445962 |
60 | Syringomyelia (HP:0003396) | 2.16108234 |
61 | Spinal cord lesions (HP:0100561) | 2.16108234 |
62 | Axonal loss (HP:0003447) | 2.14802142 |
63 | Conjunctival telangiectasia (HP:0000524) | 2.13986107 |
64 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.12447634 |
65 | Increased density of long bones (HP:0006392) | 2.12333354 |
66 | Myositis (HP:0100614) | 2.12211320 |
67 | Platyspondyly (HP:0000926) | 2.11991544 |
68 | Aneurysm (HP:0002617) | 2.11448298 |
69 | Distal upper limb amyotrophy (HP:0007149) | 2.11293077 |
70 | Upper limb amyotrophy (HP:0009129) | 2.11293077 |
71 | Aortic regurgitation (HP:0001659) | 2.10813393 |
72 | Thin bony cortex (HP:0002753) | 2.10773282 |
73 | Lipoatrophy (HP:0100578) | 2.10530317 |
74 | Abnormal delivery (HP:0001787) | 2.10355711 |
75 | Mesomelia (HP:0003027) | 2.10308854 |
76 | Mitral regurgitation (HP:0001653) | 2.10078140 |
77 | Flat acetabular roof (HP:0003180) | 2.08991812 |
78 | Abnormality of the Achilles tendon (HP:0005109) | 2.07248242 |
79 | Abnormality of the calcaneus (HP:0008364) | 2.05296357 |
80 | Abnormality of glycolipid metabolism (HP:0010969) | 2.05138480 |
81 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.05138480 |
82 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.05138480 |
83 | Thrombocytosis (HP:0001894) | 2.02480878 |
84 | Cardiovascular calcification (HP:0011915) | 2.01107685 |
85 | Mitral valve prolapse (HP:0001634) | 2.00920900 |
86 | Follicular hyperkeratosis (HP:0007502) | 2.00238519 |
87 | Radial bowing (HP:0002986) | 2.00091164 |
88 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.99658218 |
89 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.97357801 |
90 | Short 4th metacarpal (HP:0010044) | 1.97357801 |
91 | Camptodactyly of toe (HP:0001836) | 1.97155510 |
92 | Mesangial abnormality (HP:0001966) | 1.96312930 |
93 | Generalized amyotrophy (HP:0003700) | 1.93516017 |
94 | Xanthomatosis (HP:0000991) | 1.92797566 |
95 | Hypertriglyceridemia (HP:0002155) | 1.92493921 |
96 | Nemaline bodies (HP:0003798) | 1.92437561 |
97 | Dysostosis multiplex (HP:0000943) | 1.92313456 |
98 | Asymmetry of the thorax (HP:0001555) | 1.91418692 |
99 | Increased IgM level (HP:0003496) | 1.87847578 |
100 | Cupped ribs (HP:0000887) | 1.87636897 |
101 | Amyloidosis (HP:0011034) | 1.86860220 |
102 | Polycythemia (HP:0001901) | 1.83231052 |
103 | Abnormality of the common coagulation pathway (HP:0010990) | 1.83046520 |
104 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.82895180 |
105 | Eczematoid dermatitis (HP:0000976) | 1.82161846 |
106 | Tetraparesis (HP:0002273) | 1.82128723 |
107 | Gastrointestinal dysmotility (HP:0002579) | 1.81752525 |
108 | Flexion contracture of toe (HP:0005830) | 1.81735825 |
109 | Joint contractures involving the joints of the feet (HP:0100492) | 1.81735825 |
110 | Systemic lupus erythematosus (HP:0002725) | 1.80578382 |
111 | Nuclear cataract (HP:0100018) | 1.80203912 |
112 | Lower limb amyotrophy (HP:0007210) | 1.79843883 |
113 | Ectopia lentis (HP:0001083) | 1.79509651 |
114 | Genu recurvatum (HP:0002816) | 1.79443516 |
115 | Ovoid vertebral bodies (HP:0003300) | 1.79299082 |
116 | Coxa vara (HP:0002812) | 1.78523477 |
117 | Bicuspid aortic valve (HP:0001647) | 1.78125684 |
118 | Achilles tendon contracture (HP:0001771) | 1.77972153 |
119 | Lumbar hyperlordosis (HP:0002938) | 1.77623989 |
120 | Vertebral hypoplasia (HP:0008417) | 1.77403638 |
121 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.77403638 |
122 | Recurrent abscess formation (HP:0002722) | 1.76415193 |
123 | Difficulty climbing stairs (HP:0003551) | 1.76161454 |
124 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.75412173 |
125 | Elbow flexion contracture (HP:0002987) | 1.74399514 |
126 | Aortic valve stenosis (HP:0001650) | 1.73539423 |
127 | Mucopolysacchariduria (HP:0008155) | 1.73353228 |
128 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.73353228 |
129 | Increased cerebral lipofuscin (HP:0011813) | 1.73243607 |
130 | Selective tooth agenesis (HP:0001592) | 1.73010302 |
131 | Wrist flexion contracture (HP:0001239) | 1.72607919 |
132 | Striae distensae (HP:0001065) | 1.72258860 |
133 | Scapular winging (HP:0003691) | 1.71175984 |
134 | Short nail (HP:0001799) | 1.71089124 |
135 | Asymmetric septal hypertrophy (HP:0001670) | 1.71025625 |
136 | Slender build (HP:0001533) | 1.70389094 |
137 | Joint hemorrhage (HP:0005261) | 1.69386638 |
138 | Ulnar bowing (HP:0003031) | 1.69333475 |
139 | Broad palm (HP:0001169) | 1.69009975 |
140 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.68949681 |
141 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.68949681 |
142 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.68949681 |
143 | Bowel diverticulosis (HP:0005222) | 1.68676537 |
144 | Hand muscle atrophy (HP:0009130) | 1.68386461 |
145 | Bowed forearm bones (HP:0003956) | 1.68191389 |
146 | Bowing of the arm (HP:0006488) | 1.68191389 |
147 | Petechiae (HP:0000967) | 1.67383802 |
148 | Breech presentation (HP:0001623) | 1.67342196 |
149 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.66082673 |
150 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.65184669 |
151 | Osteopenia (HP:0000938) | 1.63640726 |
152 | Limb-girdle muscle atrophy (HP:0003797) | 1.62027869 |
153 | Hypoplasia of the iris (HP:0007676) | 1.62000723 |
154 | Joint laxity (HP:0001388) | 1.61297143 |
155 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.60945349 |
156 | Chondrocalcinosis (HP:0000934) | 1.60333503 |
157 | Abnormality of the odontoid process (HP:0003310) | 1.59737821 |
158 | Hypoplasia of the odontoid process (HP:0003311) | 1.58643196 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 3.74859715 |
2 | MYLK | 3.14601901 |
3 | TTN | 2.87099413 |
4 | ERN1 | 2.68826376 |
5 | TESK1 | 2.66229423 |
6 | PKN2 | 2.49656091 |
7 | TGFBR2 | 2.21578648 |
8 | MAP3K12 | 2.20098959 |
9 | KDR | 2.08366463 |
10 | LIMK1 | 2.06633390 |
11 | MST4 | 2.05626919 |
12 | BMX | 2.04361604 |
13 | PIM2 | 2.03001904 |
14 | KIT | 1.97202339 |
15 | TRPM7 | 1.88982045 |
16 | FLT3 | 1.87215617 |
17 | TIE1 | 1.81421406 |
18 | ARAF | 1.78544396 |
19 | LRRK2 | 1.77048895 |
20 | TAOK3 | 1.76172279 |
21 | TESK2 | 1.73954445 |
22 | NEK9 | 1.69973415 |
23 | JAK3 | 1.67912185 |
24 | MAP2K3 | 1.60964904 |
25 | TBK1 | 1.59574502 |
26 | RIPK4 | 1.49852609 |
27 | TGFBR1 | 1.49811713 |
28 | EPHB2 | 1.46503887 |
29 | PIK3CG | 1.43943107 |
30 | EPHA3 | 1.41623045 |
31 | EPHB1 | 1.41380845 |
32 | STK10 | 1.38187282 |
33 | PDGFRA | 1.37448503 |
34 | MAPKAPK3 | 1.37087157 |
35 | ZAP70 | 1.36702798 |
36 | PAK4 | 1.35424365 |
37 | TYK2 | 1.29250759 |
38 | PTK6 | 1.26892576 |
39 | DMPK | 1.25469254 |
40 | MAP4K1 | 1.25432792 |
41 | FGFR4 | 1.18374286 |
42 | VRK2 | 1.17964488 |
43 | ERBB3 | 1.17470709 |
44 | EEF2K | 1.15960845 |
45 | GRK5 | 1.15943887 |
46 | RPS6KA4 | 1.15911501 |
47 | PAK2 | 1.15628243 |
48 | IRAK3 | 1.11240248 |
49 | ZAK | 1.10121029 |
50 | MAP3K3 | 1.05786779 |
51 | PIK3CA | 1.03435017 |
52 | SIK1 | 1.02970394 |
53 | BTK | 1.00812293 |
54 | FER | 1.00777451 |
55 | NME2 | 1.00426397 |
56 | PTK2 | 0.98852161 |
57 | FGR | 0.95889813 |
58 | GRK7 | 0.95327878 |
59 | BLK | 0.94921319 |
60 | SCYL2 | 0.92667272 |
61 | PRKG2 | 0.92445240 |
62 | BRSK2 | 0.90624541 |
63 | ABL2 | 0.89113320 |
64 | RIPK1 | 0.88399623 |
65 | NUAK1 | 0.88390788 |
66 | PRKD2 | 0.87533448 |
67 | ROCK2 | 0.86217715 |
68 | DDR2 | 0.86150297 |
69 | DAPK1 | 0.85281509 |
70 | EIF2AK1 | 0.83797497 |
71 | MAP3K14 | 0.82927230 |
72 | PTK2B | 0.82764682 |
73 | SIK3 | 0.82609258 |
74 | * ILK | 0.81989244 |
75 | OBSCN | 0.81151102 |
76 | IRAK4 | 0.80652782 |
77 | ERBB4 | 0.77914383 |
78 | PRKD1 | 0.77892680 |
79 | JAK1 | 0.75911645 |
80 | GRK6 | 0.74241859 |
81 | BCKDK | 0.73917086 |
82 | TEC | 0.73595169 |
83 | STK24 | 0.72047245 |
84 | MAP3K5 | 0.71161983 |
85 | BMPR2 | 0.70470024 |
86 | EPHA2 | 0.70272264 |
87 | IKBKE | 0.70249735 |
88 | ROCK1 | 0.67749233 |
89 | MOS | 0.67085375 |
90 | CDC42BPA | 0.65651866 |
91 | CSF1R | 0.65325814 |
92 | MAP3K11 | 0.65237586 |
93 | MAPKAPK2 | 0.62035001 |
94 | ADRBK1 | 0.60899357 |
95 | BUB1 | 0.56446650 |
96 | ITK | 0.55708052 |
97 | IKBKB | 0.54812058 |
98 | TXK | 0.53481470 |
99 | HCK | 0.53459381 |
100 | STK38 | 0.51968532 |
101 | PDK2 | 0.51931641 |
102 | PLK2 | 0.51915601 |
103 | LMTK2 | 0.50759150 |
104 | MET | 0.50228803 |
105 | CDK8 | 0.50097760 |
106 | MAP3K8 | 0.49682434 |
107 | RPS6KA6 | 0.49388162 |
108 | PDGFRB | 0.48401739 |
109 | FES | 0.47741231 |
110 | DAPK3 | 0.47205611 |
111 | CHUK | 0.46736197 |
112 | SYK | 0.46656724 |
113 | STK3 | 0.45807804 |
114 | MARK3 | 0.45332135 |
115 | MAP3K10 | 0.45324160 |
116 | GSK3A | 0.44935216 |
117 | MATK | 0.44252399 |
118 | MUSK | 0.43998688 |
119 | FGFR1 | 0.43367458 |
120 | PRKCH | 0.42944407 |
121 | RPS6KB2 | 0.42460870 |
122 | RPS6KL1 | 0.39942346 |
123 | RPS6KC1 | 0.39942346 |
124 | CLK1 | 0.39936433 |
125 | RPS6KA2 | 0.39769165 |
126 | ACVR1B | 0.39515220 |
127 | CDK14 | 0.39145190 |
128 | MAP3K1 | 0.38694473 |
129 | CSK | 0.38298352 |
130 | PIM1 | 0.38035576 |
131 | TAOK2 | 0.37624505 |
132 | FGFR3 | 0.36746996 |
133 | CAMK2G | 0.36610185 |
134 | SRC | 0.36549211 |
135 | BRSK1 | 0.36193667 |
136 | * PAK1 | 0.33706854 |
137 | NTRK1 | 0.29727629 |
138 | STK4 | 0.27272805 |
139 | PAK3 | 0.26422501 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 2.53610358 |
2 | * Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 2.36002807 |
3 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.20961489 |
4 | * Focal adhesion_Homo sapiens_hsa04510 | 2.06489152 |
5 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 2.03484952 |
6 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.96973566 |
7 | Leishmaniasis_Homo sapiens_hsa05140 | 1.96458766 |
8 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.88001896 |
9 | Shigellosis_Homo sapiens_hsa05131 | 1.87054612 |
10 | Viral myocarditis_Homo sapiens_hsa05416 | 1.85696990 |
11 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.84790534 |
12 | Malaria_Homo sapiens_hsa05144 | 1.83938730 |
13 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.79685924 |
14 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.67789851 |
15 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.67345463 |
16 | Lysosome_Homo sapiens_hsa04142 | 1.61313161 |
17 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.58299314 |
18 | Legionellosis_Homo sapiens_hsa05134 | 1.55679825 |
19 | Other glycan degradation_Homo sapiens_hsa00511 | 1.54720916 |
20 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.52988537 |
21 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.47750237 |
22 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.47338504 |
23 | Proteasome_Homo sapiens_hsa03050 | 1.46246149 |
24 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.46184174 |
25 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.45586093 |
26 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.41571764 |
27 | Measles_Homo sapiens_hsa05162 | 1.40105152 |
28 | Apoptosis_Homo sapiens_hsa04210 | 1.37820260 |
29 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.35210164 |
30 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.35127155 |
31 | Amoebiasis_Homo sapiens_hsa05146 | 1.33831134 |
32 | DNA replication_Homo sapiens_hsa03030 | 1.29802022 |
33 | Protein export_Homo sapiens_hsa03060 | 1.27499036 |
34 | Adherens junction_Homo sapiens_hsa04520 | 1.27391200 |
35 | Platelet activation_Homo sapiens_hsa04611 | 1.26141218 |
36 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.26000968 |
37 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.24468032 |
38 | Pertussis_Homo sapiens_hsa05133 | 1.23630014 |
39 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.17267774 |
40 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.16160624 |
41 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.15648407 |
42 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.13579299 |
43 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.12151553 |
44 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.10002239 |
45 | Galactose metabolism_Homo sapiens_hsa00052 | 1.06021196 |
46 | Salmonella infection_Homo sapiens_hsa05132 | 1.05282880 |
47 | Phagosome_Homo sapiens_hsa04145 | 1.05093850 |
48 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.04830458 |
49 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.02727274 |
50 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.01665398 |
51 | Hepatitis B_Homo sapiens_hsa05161 | 1.01460579 |
52 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.97591834 |
53 | Cell cycle_Homo sapiens_hsa04110 | 0.95533359 |
54 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.95202134 |
55 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.94964736 |
56 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.94884430 |
57 | HTLV-I infection_Homo sapiens_hsa05166 | 0.94018616 |
58 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.93639319 |
59 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.93637347 |
60 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.93465733 |
61 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.92122247 |
62 | Bladder cancer_Homo sapiens_hsa05219 | 0.90665326 |
63 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.89512967 |
64 | Gap junction_Homo sapiens_hsa04540 | 0.89483508 |
65 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.87751598 |
66 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.84752671 |
67 | Influenza A_Homo sapiens_hsa05164 | 0.84323727 |
68 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.84006907 |
69 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.83749524 |
70 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.83507156 |
71 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.82440023 |
72 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.82017166 |
73 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.81796531 |
74 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.80519458 |
75 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.79400291 |
76 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.78991301 |
77 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.78970167 |
78 | Base excision repair_Homo sapiens_hsa03410 | 0.78128570 |
79 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.78090473 |
80 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.77715932 |
81 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.76493299 |
82 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.76049667 |
83 | Tuberculosis_Homo sapiens_hsa05152 | 0.75935596 |
84 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.72950263 |
85 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.72087633 |
86 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.70689851 |
87 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.70614264 |
88 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.69740841 |
89 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.69513052 |
90 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.69063342 |
91 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.66543380 |
92 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.65302373 |
93 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.64700797 |
94 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.64540951 |
95 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.61912409 |
96 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.61345330 |
97 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.60064425 |
98 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.59946801 |
99 | Pathways in cancer_Homo sapiens_hsa05200 | 0.58953709 |
100 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.57997708 |
101 | Endocytosis_Homo sapiens_hsa04144 | 0.57828059 |
102 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.56455149 |
103 | Sulfur relay system_Homo sapiens_hsa04122 | 0.56249945 |
104 | Thyroid cancer_Homo sapiens_hsa05216 | 0.54933221 |
105 | Colorectal cancer_Homo sapiens_hsa05210 | 0.53908707 |
106 | Insulin resistance_Homo sapiens_hsa04931 | 0.53514536 |
107 | Carbon metabolism_Homo sapiens_hsa01200 | 0.53053634 |
108 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.51877227 |
109 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.50372843 |
110 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.49748595 |
111 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.49710569 |
112 | Hepatitis C_Homo sapiens_hsa05160 | 0.48279202 |
113 | Allograft rejection_Homo sapiens_hsa05330 | 0.46483515 |
114 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.46463205 |
115 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.45863312 |
116 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.44856377 |
117 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.42947617 |
118 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.41408511 |
119 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.39624664 |
120 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.39299889 |
121 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.39075411 |
122 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.38976754 |
123 | Prostate cancer_Homo sapiens_hsa05215 | 0.38760440 |
124 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.37929622 |
125 | Melanoma_Homo sapiens_hsa05218 | 0.37211991 |
126 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.36573629 |
127 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.36316369 |
128 | Tight junction_Homo sapiens_hsa04530 | 0.35200254 |
129 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.34527256 |
130 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.28648582 |
131 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.28436131 |