IMMT

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1tricarboxylic acid cycle (GO:0006099)8.22736177
2regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)6.35600825
3regulation of acyl-CoA biosynthetic process (GO:0050812)5.78644228
4sarcomere organization (GO:0045214)5.73204304
5oxidative phosphorylation (GO:0006119)5.63566488
6regulation of coenzyme metabolic process (GO:0051196)5.57133697
7regulation of cofactor metabolic process (GO:0051193)5.57133697
8cardiac myofibril assembly (GO:0055003)5.55195580
9NADH metabolic process (GO:0006734)5.53018474
10mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.47511402
11carnitine shuttle (GO:0006853)5.36676755
12actin-myosin filament sliding (GO:0033275)5.21225464
13muscle filament sliding (GO:0030049)5.21225464
14mitotic chromosome condensation (GO:0007076)5.03421048
15energy coupled proton transport, down electrochemical gradient (GO:0015985)4.92455587
16ATP synthesis coupled proton transport (GO:0015986)4.92455587
17myofibril assembly (GO:0030239)4.90706532
18negative regulation of potassium ion transmembrane transporter activity (GO:1901017)4.71853329
19lysine catabolic process (GO:0006554)4.70378071
20lysine metabolic process (GO:0006553)4.70378071
21fatty acid transmembrane transport (GO:1902001)4.67453794
22respiratory electron transport chain (GO:0022904)4.39138062
23regulation of sulfur metabolic process (GO:0042762)4.36661431
24actin-mediated cell contraction (GO:0070252)4.35801335
25establishment of integrated proviral latency (GO:0075713)4.30115338
26cardiac muscle cell development (GO:0055013)4.28698775
27protein localization to kinetochore (GO:0034501)4.27165474
28carnitine transmembrane transport (GO:1902603)4.26424859
29electron transport chain (GO:0022900)4.26392433
30cardiac muscle contraction (GO:0060048)4.24545029
31DNA strand elongation (GO:0022616)4.23641026
32mitotic metaphase plate congression (GO:0007080)4.21348064
33amino-acid betaine transport (GO:0015838)4.20722865
34carnitine transport (GO:0015879)4.20722865
35protein localization to chromosome, centromeric region (GO:0071459)4.19839411
36branched-chain amino acid catabolic process (GO:0009083)4.19344041
37regulation of sequestering of triglyceride (GO:0010889)4.15231156
38negative regulation of potassium ion transmembrane transport (GO:1901380)4.14911940
39formation of translation preinitiation complex (GO:0001731)4.12264182
40mitotic sister chromatid segregation (GO:0000070)4.11336128
41succinate metabolic process (GO:0006105)4.10766891
42heart process (GO:0003015)4.05780629
43heart contraction (GO:0060047)4.05780629
44mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.02558660
45telomere maintenance via semi-conservative replication (GO:0032201)4.02184698
46cardiac cell development (GO:0055006)4.01137591
47sister chromatid segregation (GO:0000819)3.93543990
48IMP biosynthetic process (GO:0006188)3.91936657
49aspartate family amino acid catabolic process (GO:0009068)3.91209705
50tricarboxylic acid metabolic process (GO:0072350)3.87127477
51fatty acid beta-oxidation (GO:0006635)3.86797713
52ubiquinone biosynthetic process (GO:0006744)3.85742120
53quinone biosynthetic process (GO:1901663)3.85742120
542-oxoglutarate metabolic process (GO:0006103)3.85080116
55cardiac muscle tissue morphogenesis (GO:0055008)3.84430189
56oxaloacetate metabolic process (GO:0006107)3.82513415
57regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.74542111
58ribosome assembly (GO:0042255)3.74051208
59positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.70890372
60pore complex assembly (GO:0046931)3.70302674
61branched-chain amino acid metabolic process (GO:0009081)3.69883398
62DNA replication checkpoint (GO:0000076)3.67965214
63metaphase plate congression (GO:0051310)3.66634941
64actomyosin structure organization (GO:0031032)3.65871201
65regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.64371150
66mitotic nuclear envelope disassembly (GO:0007077)3.64294697
67regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.63802496
68mitotic sister chromatid cohesion (GO:0007064)3.61914130
69regulation of skeletal muscle contraction (GO:0014819)3.61713901
70IMP metabolic process (GO:0046040)3.55857536
71DNA replication initiation (GO:0006270)3.53548330
72bundle of His cell to Purkinje myocyte communication (GO:0086069)3.52075681
73ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.52043361
74regulation of relaxation of muscle (GO:1901077)3.48425407
75muscle tissue morphogenesis (GO:0060415)3.44111308
76CENP-A containing nucleosome assembly (GO:0034080)3.43591566
77ubiquinone metabolic process (GO:0006743)3.43092763
78nuclear envelope disassembly (GO:0051081)3.42123309
79membrane disassembly (GO:0030397)3.42123309
80tRNA aminoacylation for protein translation (GO:0006418)3.41164253
81regulation of translational fidelity (GO:0006450)3.41053609
82striated muscle contraction (GO:0006941)3.38321751
83cardiac muscle hypertrophy (GO:0003300)3.37322136
84purine nucleobase biosynthetic process (GO:0009113)3.35545484
85regulation of actin filament-based movement (GO:1903115)3.35495361
86telomere maintenance via recombination (GO:0000722)3.35057779
87chromatin remodeling at centromere (GO:0031055)3.34435122
88tRNA aminoacylation (GO:0043039)3.32348397
89amino acid activation (GO:0043038)3.32348397
90mitotic recombination (GO:0006312)3.32035632
91quaternary ammonium group transport (GO:0015697)3.30595994
92regulation of sarcomere organization (GO:0060297)3.29685763
93establishment of viral latency (GO:0019043)3.28631663
94aerobic respiration (GO:0009060)3.28077381
95valine metabolic process (GO:0006573)3.26547604
96folic acid-containing compound biosynthetic process (GO:0009396)3.26479116
97lipid particle organization (GO:0034389)3.24357145
98regulation of mitotic spindle organization (GO:0060236)3.23204043
99ATP biosynthetic process (GO:0006754)3.22117289
100ventricular cardiac muscle cell development (GO:0055015)3.19333988
101regulation of fatty acid oxidation (GO:0046320)3.17276992
102non-recombinational repair (GO:0000726)3.17152465
103double-strand break repair via nonhomologous end joining (GO:0006303)3.17152465
104plasma membrane repair (GO:0001778)3.16928608
105anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.16331448
106adult heart development (GO:0007512)3.16302748
107positive regulation of chromosome segregation (GO:0051984)3.16145244
108striated muscle hypertrophy (GO:0014897)3.15667589
109fatty acid oxidation (GO:0019395)3.14157455
110DNA ligation (GO:0006266)3.13677448
111regulation of spindle organization (GO:0090224)3.13557853
112acetyl-CoA metabolic process (GO:0006084)3.12409581
113chromosome condensation (GO:0030261)3.11818773
114regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.11565731
115purine ribonucleoside monophosphate biosynthetic process (GO:0009168)3.10554187
116purine nucleoside monophosphate biosynthetic process (GO:0009127)3.10554187
117regulation of mitochondrial translation (GO:0070129)3.10262655
118ventricular cardiac muscle cell action potential (GO:0086005)3.09096500
119nucleotide-excision repair, DNA gap filling (GO:0006297)3.06705954
120lipid oxidation (GO:0034440)3.06372552
121biotin metabolic process (GO:0006768)3.06288259
122establishment of chromosome localization (GO:0051303)3.05606489
123DNA topological change (GO:0006265)3.05538999
124spindle checkpoint (GO:0031577)3.05507300
125fatty acid catabolic process (GO:0009062)3.05496956
126regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.05106387
127actin filament-based movement (GO:0030048)3.05092500
128regulation of chromosome segregation (GO:0051983)3.04942234
129carnitine metabolic process (GO:0009437)3.01432800
130cellular respiration (GO:0045333)2.99812332
131mitotic spindle checkpoint (GO:0071174)2.98689615
132ribosome biogenesis (GO:0042254)2.98097052
133regulation of sister chromatid cohesion (GO:0007063)2.97855447
134negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.96938155
135negative regulation of chromosome segregation (GO:0051985)2.93761341
136chromosome segregation (GO:0007059)2.91702609
137Golgi transport vesicle coating (GO:0048200)2.90319856
138COPI coating of Golgi vesicle (GO:0048205)2.90319856
139DNA replication-independent nucleosome assembly (GO:0006336)2.90074754
140DNA replication-independent nucleosome organization (GO:0034724)2.90074754
141proteasome assembly (GO:0043248)2.90049995
142positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.88942512
143heart trabecula formation (GO:0060347)2.87978967
144kinetochore organization (GO:0051383)2.87190119
145regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.86182700
146negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.84795874
147protein localization to chromosome (GO:0034502)2.84779257
148nuclear pore organization (GO:0006999)2.84609050
149negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.84204322
150negative regulation of mitotic sister chromatid segregation (GO:0033048)2.84204322
151negative regulation of mitotic sister chromatid separation (GO:2000816)2.84204322
152negative regulation of sister chromatid segregation (GO:0033046)2.84204322
153negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.84204322
154telomere maintenance via telomere lengthening (GO:0010833)2.82864097
155mitotic spindle assembly checkpoint (GO:0007094)2.82746475
156negative regulation of striated muscle cell apoptotic process (GO:0010664)2.82521988
157pyruvate metabolic process (GO:0006090)2.82122746
158nucleobase biosynthetic process (GO:0046112)2.81912946
159regulation of centriole replication (GO:0046599)2.81489767
160histone exchange (GO:0043486)2.80863277
161nucleobase-containing small molecule interconversion (GO:0015949)2.80390950
162spindle assembly checkpoint (GO:0071173)2.80062634
163regulation of the force of heart contraction (GO:0002026)2.78888403
164regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.76931271
165regulation of mitotic metaphase/anaphase transition (GO:0030071)2.76931271
166regulation of cell communication by electrical coupling (GO:0010649)2.75315760
167meiotic chromosome segregation (GO:0045132)2.74644085
168negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.74380212
169negative regulation of ligase activity (GO:0051352)2.74380212
170glycolytic process (GO:0006096)2.74143377
171mitochondrial fusion (GO:0008053)2.73198773
172nuclear envelope organization (GO:0006998)2.72975595
173DNA packaging (GO:0006323)2.72677983
174somatic hypermutation of immunoglobulin genes (GO:0016446)2.72627304
175somatic diversification of immune receptors via somatic mutation (GO:0002566)2.72627304
176DNA unwinding involved in DNA replication (GO:0006268)2.72531534
177DNA duplex unwinding (GO:0032508)2.71467455
178regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.71217133
179nuclear pore complex assembly (GO:0051292)2.70912550
180regulation of sister chromatid segregation (GO:0033045)2.70905524
181regulation of mitotic sister chromatid separation (GO:0010965)2.70905524
182regulation of mitotic sister chromatid segregation (GO:0033047)2.70905524
183ribonucleoprotein complex biogenesis (GO:0022613)2.70452672
184ribonucleoside monophosphate biosynthetic process (GO:0009156)2.70365488
185proline biosynthetic process (GO:0006561)2.69901297
186regulation of striated muscle contraction (GO:0006942)2.69463729
187DNA strand elongation involved in DNA replication (GO:0006271)2.69079588
188ribosomal large subunit biogenesis (GO:0042273)2.67265491

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.39852372
2* PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.65278509
3* MYC_18555785_ChIP-Seq_MESCs_Mouse3.88625102
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.80163476
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.54291526
6TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.49809135
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.04741088
8FOXM1_23109430_ChIP-Seq_U2OS_Human2.93815138
9* ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.87416819
10CREB1_15753290_ChIP-ChIP_HEK293T_Human2.67975210
11AR_21909140_ChIP-Seq_LNCAP_Human2.63747300
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.59218566
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.56307157
14* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.55181253
15MYC_18358816_ChIP-ChIP_MESCs_Mouse2.52045259
16* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.47518531
17FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.35129119
18* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.31561836
19ETS1_20019798_ChIP-Seq_JURKAT_Human2.30419120
20MYC_19079543_ChIP-ChIP_MESCs_Mouse2.29706766
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.28285045
22E2F1_18555785_ChIP-Seq_MESCs_Mouse2.16040558
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.15054652
24* SRF_21415370_ChIP-Seq_HL-1_Mouse2.11944837
25YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.05628893
26GABP_17652178_ChIP-ChIP_JURKAT_Human2.05442171
27* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.02813257
28* GATA4_21415370_ChIP-Seq_HL-1_Mouse1.86935316
29MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.83046843
30* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.81273865
31DCP1A_22483619_ChIP-Seq_HELA_Human1.80271489
32STAT3_1855785_ChIP-Seq_MESCs_Mouse1.79367862
33NANOG_18555785_ChIP-Seq_MESCs_Mouse1.78381355
34E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.77881524
35RBPJ_22232070_ChIP-Seq_NCS_Mouse1.72254210
36ZFX_18555785_ChIP-Seq_MESCs_Mouse1.69387895
37E2F1_21310950_ChIP-Seq_MCF-7_Human1.67571399
38ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.66896560
39* MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.66761671
40MYCN_18555785_ChIP-Seq_MESCs_Mouse1.66199620
41* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.62691921
42XRN2_22483619_ChIP-Seq_HELA_Human1.60609519
43MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.56952118
44BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.54108068
45FOXP3_21729870_ChIP-Seq_TREG_Human1.53686189
46EP300_21415370_ChIP-Seq_HL-1_Mouse1.52932168
47* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.52559960
48HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.51854289
49NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.50310939
50* VDR_23849224_ChIP-Seq_CD4+_Human1.50071791
51PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.49242923
52POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.46125555
53FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.45125688
54NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.44053630
55CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.42778276
56* YY1_21170310_ChIP-Seq_MESCs_Mouse1.42608534
57ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.40989326
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.39950607
59* GABP_19822575_ChIP-Seq_HepG2_Human1.39030043
60* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.36949608
61TTF2_22483619_ChIP-Seq_HELA_Human1.34753331
62EGR1_19374776_ChIP-ChIP_THP-1_Human1.34682344
63POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.33245528
64ELK1_19687146_ChIP-ChIP_HELA_Human1.32069085
65* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.27710488
66CIITA_25753668_ChIP-Seq_RAJI_Human1.25306015
67TBX20_22080862_ChIP-Seq_HEART_Mouse1.24445165
68TBX20_22328084_ChIP-Seq_HEART_Mouse1.24445165
69MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.21034882
70SOX2_18555785_ChIP-Seq_MESCs_Mouse1.20799623
71PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.20675934
72CLOCK_20551151_ChIP-Seq_293T_Human1.20398739
73PADI4_21655091_ChIP-ChIP_MCF-7_Human1.19081429
74CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.18533768
75* PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.17700785
76ELF1_17652178_ChIP-ChIP_JURKAT_Human1.17532803
77HOXB4_20404135_ChIP-ChIP_EML_Mouse1.16238741
78ZNF263_19887448_ChIP-Seq_K562_Human1.15843212
79DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.15404861
80* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12371682
81TBX5_21415370_ChIP-Seq_HL-1_Mouse1.11636437
82CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.05744184
83HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.05558712
84CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.04275698
85RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.04113921
86* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.01854299
87HIF1A_21447827_ChIP-Seq_MCF-7_Human1.01201240
88SALL1_21062744_ChIP-ChIP_HESCs_Human1.01114558
89* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.00056215
90* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.97737695
91SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.97319497
92SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.96412013
93SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.95654823
94NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.94473783
95NANOG_21062744_ChIP-ChIP_HESCs_Human0.93835183
96PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.90984523
97SOX17_20123909_ChIP-Seq_XEN_Mouse0.90819044
98* TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.90705082
99TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.90234273
100KDM5A_27292631_Chip-Seq_BREAST_Human0.88564649
101SOX2_18692474_ChIP-Seq_MEFs_Mouse0.88129910
102* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.86311311
103TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.84111468
104ESR1_15608294_ChIP-ChIP_MCF-7_Human0.83852119
105TFEB_21752829_ChIP-Seq_HELA_Human0.83605983
106E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.81088238
107MYC_18940864_ChIP-ChIP_HL60_Human0.80921602
108NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.80735781
109SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.80117850
110RARG_19884340_ChIP-ChIP_MEFs_Mouse0.80041623
111GATA1_22025678_ChIP-Seq_K562_Human0.79441031
112HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.79275041
113HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.78873359
114ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.77993605
115CHD1_26751641_Chip-Seq_LNCaP_Human0.77816461
116CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.77521394
117* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.77391413
118MYC_22102868_ChIP-Seq_BL_Human0.77281757
119ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.75850784
120GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.75722867

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis5.04237007
2MP0004084_abnormal_cardiac_muscle5.02255078
3MP0003646_muscle_fatigue5.01013246
4MP0004215_abnormal_myocardial_fiber3.71088450
5MP0000751_myopathy3.56735625
6MP0004036_abnormal_muscle_relaxation3.56632867
7MP0000749_muscle_degeneration3.46296696
8MP0005330_cardiomyopathy3.37964787
9MP0008775_abnormal_heart_ventricle2.81334307
10MP0006036_abnormal_mitochondrial_physio2.73441377
11MP0002972_abnormal_cardiac_muscle2.68118601
12MP0003806_abnormal_nucleotide_metabolis2.63501113
13MP0005670_abnormal_white_adipose2.63364594
14MP0004087_abnormal_muscle_fiber2.57607803
15MP0004130_abnormal_muscle_cell2.52572314
16MP0002269_muscular_atrophy2.34517155
17MP0003221_abnormal_cardiomyocyte_apopto2.32030882
18MP0005620_abnormal_muscle_contractility2.29187229
19MP0003718_maternal_effect2.27846819
20MP0001544_abnormal_cardiovascular_syste2.22091775
21MP0005385_cardiovascular_system_phenoty2.22091775
22MP0000750_abnormal_muscle_regeneration2.19324522
23MP0010630_abnormal_cardiac_muscle2.19110389
24MP0005666_abnormal_adipose_tissue2.04519710
25MP0006138_congestive_heart_failure2.04126730
26MP0002106_abnormal_muscle_physiology2.01034013
27MP0003137_abnormal_impulse_conducting1.99563209
28MP0004484_altered_response_of1.97367953
29MP0004233_abnormal_muscle_weight1.95721940
30MP0003950_abnormal_plasma_membrane1.82488782
31MP0006035_abnormal_mitochondrial_morpho1.76352105
32MP0005451_abnormal_body_composition1.70439936
33MP0003567_abnormal_fetal_cardiomyocyte1.70364986
34MP0000747_muscle_weakness1.69470017
35MP0003786_premature_aging1.67913464
36MP0001661_extended_life_span1.64902634
37MP0004043_abnormal_pH_regulation1.64784332
38MP0005369_muscle_phenotype1.61303566
39MP0000759_abnormal_skeletal_muscle1.61167606
40MP0010094_abnormal_chromosome_stability1.60988820
41MP0004145_abnormal_muscle_electrophysio1.55231881
42MP0003828_pulmonary_edema1.53264924
43MP0002127_abnormal_cardiovascular_syste1.43107489
44MP0005266_abnormal_metabolism1.43033789
45MP0004957_abnormal_blastocyst_morpholog1.39380926
46MP0003123_paternal_imprinting1.38448177
47MP0002877_abnormal_melanocyte_morpholog1.37348873
48MP0004085_abnormal_heartbeat1.36837460
49MP0003111_abnormal_nucleus_morphology1.31176139
50MP0003693_abnormal_embryo_hatching1.30956228
51MP0000372_irregular_coat_pigmentation1.30657575
52MP0003941_abnormal_skin_development1.29978174
53MP0003186_abnormal_redox_activity1.28566020
54MP0002332_abnormal_exercise_endurance1.25838035
55MP0003077_abnormal_cell_cycle1.25768608
56MP0004147_increased_porphyrin_level1.24137801
57MP0000313_abnormal_cell_death1.21748070
58MP0010307_abnormal_tumor_latency1.21190357
59MP0001730_embryonic_growth_arrest1.16332454
60MP0003984_embryonic_growth_retardation1.16169336
61MP0010030_abnormal_orbit_morphology1.14189564
62MP0004185_abnormal_adipocyte_glucose1.12897500
63MP0002088_abnormal_embryonic_growth/wei1.12315422
64MP0005332_abnormal_amino_acid1.11260863
65MP0001529_abnormal_vocalization1.10045505
66MP0000266_abnormal_heart_morphology1.09477556
67MP0005375_adipose_tissue_phenotype1.07844225
68MP0002210_abnormal_sex_determination1.05124368
69MP0005380_embryogenesis_phenotype1.02214982
70MP0001672_abnormal_embryogenesis/_devel1.02214982
71MP0001929_abnormal_gametogenesis0.99757313
72MP0003315_abnormal_perineum_morphology0.97828276
73MP0008058_abnormal_DNA_repair0.96755068
74MP0002139_abnormal_hepatobiliary_system0.96600613
75MP0008057_abnormal_DNA_replication0.95953246
76MP0003890_abnormal_embryonic-extraembry0.95063624
77MP0009697_abnormal_copulation0.94567885
78MP0003566_abnormal_cell_adhesion0.90904223
79MP0005408_hypopigmentation0.90242737
80MP0008932_abnormal_embryonic_tissue0.88778273
81MP0000343_altered_response_to0.88775794
82MP0002971_abnormal_brown_adipose0.87831340
83MP0010234_abnormal_vibrissa_follicle0.86885505
84MP0005377_hearing/vestibular/ear_phenot0.85209159
85MP0003878_abnormal_ear_physiology0.85209159
86MP0001697_abnormal_embryo_size0.85011469
87MP0002938_white_spotting0.81749969
88MP0001145_abnormal_male_reproductive0.81598980
89MP0008260_abnormal_autophagy0.80654383
90MP0001293_anophthalmia0.75714641
91MP0003705_abnormal_hypodermis_morpholog0.75632325
92MP0000653_abnormal_sex_gland0.74831864
93MP0002080_prenatal_lethality0.72514340
94MP0009703_decreased_birth_body0.72435075
95MP0008007_abnormal_cellular_replicative0.71776837
96MP0005319_abnormal_enzyme/_coenzyme0.71713311
97MP0005384_cellular_phenotype0.70985432
98MP0008789_abnormal_olfactory_epithelium0.69989868
99MP0009643_abnormal_urine_homeostasis0.69525407
100MP0000358_abnormal_cell_content/0.68925174
101MP0002160_abnormal_reproductive_system0.68505643
102MP0003385_abnormal_body_wall0.67806449
103MP0005360_urolithiasis0.67558751
104MP0010352_gastrointestinal_tract_polyps0.67397169
105MP0004197_abnormal_fetal_growth/weight/0.67387397
106MP0006292_abnormal_olfactory_placode0.67000998
107MP0010368_abnormal_lymphatic_system0.65041765
108MP0000490_abnormal_crypts_of0.64960736
109MP0003937_abnormal_limbs/digits/tail_de0.64260488
110MP0004272_abnormal_basement_membrane0.63976160
111MP0000230_abnormal_systemic_arterial0.63900287
112MP0005501_abnormal_skin_physiology0.63890247
113MP0002396_abnormal_hematopoietic_system0.63837937
114MP0000003_abnormal_adipose_tissue0.63544963
115MP0002108_abnormal_muscle_morphology0.63476777
116MP0003699_abnormal_female_reproductive0.63217107
117MP0002019_abnormal_tumor_incidence0.62814671
118MP0002970_abnormal_white_adipose0.60407882
119MP0008877_abnormal_DNA_methylation0.59235379
120MP0005165_increased_susceptibility_to0.59022944
121MP0005376_homeostasis/metabolism_phenot0.59019967
122MP0008438_abnormal_cutaneous_collagen0.58645078
123MP0001764_abnormal_homeostasis0.58293495
124MP0001727_abnormal_embryo_implantation0.58234456
125MP0002086_abnormal_extraembryonic_tissu0.57720731
126MP0000350_abnormal_cell_proliferation0.56196805
127MP0002128_abnormal_blood_circulation0.55969683
128MP0004133_heterotaxia0.55377866
129MP0002085_abnormal_embryonic_tissue0.52003120
130MP0005085_abnormal_gallbladder_physiolo0.50998665
131MP0002084_abnormal_developmental_patter0.50585869
132MP0009672_abnormal_birth_weight0.50561333
133MP0000733_abnormal_muscle_development0.50403085
134MP0002078_abnormal_glucose_homeostasis0.50022263
135MP0005584_abnormal_enzyme/coenzyme_acti0.49760995
136MP0001756_abnormal_urination0.49674021
137MP0009115_abnormal_fat_cell0.49515849

Predicted human phenotypes

RankGene SetZ-score
1Exercise-induced muscle cramps (HP:0003710)5.50674974
2Myoglobinuria (HP:0002913)5.43375262
3Sudden death (HP:0001699)5.29233232
4Rhabdomyolysis (HP:0003201)4.92144300
5Ventricular tachycardia (HP:0004756)4.75117891
6Exercise-induced myalgia (HP:0003738)4.56353242
7Calf muscle hypertrophy (HP:0008981)4.47460039
8Abnormality of glycolysis (HP:0004366)4.32291052
9Increased serum pyruvate (HP:0003542)4.32291052
10Hepatic necrosis (HP:0002605)4.17354316
11Abnormal mitochondria in muscle tissue (HP:0008316)4.11856539
12Lipoatrophy (HP:0100578)4.09908503
13Muscle hypertrophy of the lower extremities (HP:0008968)4.08436220
14Palpitations (HP:0001962)3.96155944
15Acute necrotizing encephalopathy (HP:0006965)3.94684367
16Atrial fibrillation (HP:0005110)3.94049795
17Nemaline bodies (HP:0003798)3.82885269
18Chromosomal breakage induced by crosslinking agents (HP:0003221)3.80233518
19Chromsome breakage (HP:0040012)3.76546790
20Acute encephalopathy (HP:0006846)3.71692550
21Dicarboxylic aciduria (HP:0003215)3.64596866
22Abnormality of dicarboxylic acid metabolism (HP:0010995)3.64596866
23Muscle fiber splitting (HP:0003555)3.63533941
24Subaortic stenosis (HP:0001682)3.59487743
25Abnormality of the left ventricular outflow tract (HP:0011103)3.59487743
26Dilated cardiomyopathy (HP:0001644)3.56924362
27Primary atrial arrhythmia (HP:0001692)3.56455732
28Abnormality of fatty-acid metabolism (HP:0004359)3.51843722
29Supraventricular tachycardia (HP:0004755)3.50510408
30Abnormal gallbladder physiology (HP:0012438)3.49861528
31Cholecystitis (HP:0001082)3.49861528
32Abnormality of the calf musculature (HP:0001430)3.49308307
33Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.49252767
34Abnormality of alanine metabolism (HP:0010916)3.49252767
35Hyperalaninemia (HP:0003348)3.49252767
36Hepatocellular necrosis (HP:0001404)3.47456881
37Increased CSF lactate (HP:0002490)3.47452129
38Hypoglycemic coma (HP:0001325)3.45617680
39Microvesicular hepatic steatosis (HP:0001414)3.44166048
40Right ventricular cardiomyopathy (HP:0011663)3.43248730
41Supraventricular arrhythmia (HP:0005115)3.42335257
42Cerebral edema (HP:0002181)3.36275084
43Progressive muscle weakness (HP:0003323)3.25488775
44Proximal tubulopathy (HP:0000114)3.23191873
45Progressive macrocephaly (HP:0004481)3.21171671
46Hyporeflexia of lower limbs (HP:0002600)3.19166107
47Mitochondrial inheritance (HP:0001427)3.16057462
48Increased muscle lipid content (HP:0009058)3.12188536
49Hyperglycinuria (HP:0003108)3.09975669
50Lactic acidosis (HP:0003128)3.09112460
51Increased connective tissue (HP:0009025)3.09072237
52Generalized aminoaciduria (HP:0002909)3.07915908
53Ragged-red muscle fibers (HP:0003200)3.07006485
54Nausea (HP:0002018)3.06448788
55Ketoacidosis (HP:0001993)3.01723642
56Exercise intolerance (HP:0003546)3.01263168
57Progressive external ophthalmoplegia (HP:0000590)2.93656816
58Conjunctival hamartoma (HP:0100780)2.82488873
59Cortical dysplasia (HP:0002539)2.81890836
60EMG: myopathic abnormalities (HP:0003458)2.79385018
61Neoplasm of the adrenal gland (HP:0100631)2.76900997
62Decreased activity of mitochondrial respiratory chain (HP:0008972)2.69745423
63Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.69745423
64Respiratory failure (HP:0002878)2.67589695
65Increased serum lactate (HP:0002151)2.64989045
66Syncope (HP:0001279)2.62099821
67Increased nuchal translucency (HP:0010880)2.62027138
68Shoulder girdle muscle weakness (HP:0003547)2.59418335
69Increased intramyocellular lipid droplets (HP:0012240)2.55923588
70Ventricular arrhythmia (HP:0004308)2.55432063
71Bundle branch block (HP:0011710)2.54463277
72Abnormality of glycine metabolism (HP:0010895)2.53359519
73Abnormality of serine family amino acid metabolism (HP:0010894)2.53359519
74Hyperammonemia (HP:0001987)2.50426740
75Centrally nucleated skeletal muscle fibers (HP:0003687)2.50409923
76Asymmetric septal hypertrophy (HP:0001670)2.45128195
77Muscle stiffness (HP:0003552)2.43843542
78Prolonged QT interval (HP:0001657)2.39068461
79Distal lower limb muscle weakness (HP:0009053)2.38872333
80Difficulty running (HP:0009046)2.36285048
81Lethargy (HP:0001254)2.35603342
82Pheochromocytoma (HP:0002666)2.34041445
83Lipid accumulation in hepatocytes (HP:0006561)2.32920135
84Ketosis (HP:0001946)2.29768599
85Renal cortical cysts (HP:0000803)2.28877755
86Microglossia (HP:0000171)2.27984149
87Increased hepatocellular lipid droplets (HP:0006565)2.26944408
88Generalized muscle weakness (HP:0003324)2.17707029
89Abnormality of the preputium (HP:0100587)2.17660177
90Multiple enchondromatosis (HP:0005701)2.17011156
91Neuroendocrine neoplasm (HP:0100634)2.16661105
92Gout (HP:0001997)2.16349995
93Esophageal neoplasm (HP:0100751)2.16271296
94Neoplasm of head and neck (HP:0012288)2.16271296
95Birth length less than 3rd percentile (HP:0003561)2.14394902
96Myotonia (HP:0002486)2.13574566
97Abnormality of chromosome stability (HP:0003220)2.13197285
98Methylmalonic aciduria (HP:0012120)2.10362563
99Muscle fiber inclusion bodies (HP:0100299)2.10224043
100Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.09261700
101Secondary amenorrhea (HP:0000869)2.08948281
102Type 1 muscle fiber predominance (HP:0003803)2.08036364
103Premature ovarian failure (HP:0008209)2.05802271
104Reticulocytopenia (HP:0001896)2.05768811
105Abnormal lung lobation (HP:0002101)2.05676919
106Cholelithiasis (HP:0001081)2.05212557
107Reduced antithrombin III activity (HP:0001976)2.05188168
108Myopathic facies (HP:0002058)2.03640551
109Meckel diverticulum (HP:0002245)2.03484691
110Heart block (HP:0012722)2.02575233
111Metabolic acidosis (HP:0001942)2.01979161
112Volvulus (HP:0002580)1.99631383
113Abnormal gallbladder morphology (HP:0012437)1.98505118
114Rimmed vacuoles (HP:0003805)1.97309092
115Left ventricular hypertrophy (HP:0001712)1.95122120
116Neoplasm of the rectum (HP:0100743)1.94638008
117Abnormality of the anterior horn cell (HP:0006802)1.93950046
118Degeneration of anterior horn cells (HP:0002398)1.93950046
119Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.93947602
120Abnormality of urine glucose concentration (HP:0011016)1.93261415
121Glycosuria (HP:0003076)1.93261415
122Cerebral hypomyelination (HP:0006808)1.93096453
123Abnormality of reticulocytes (HP:0004312)1.92891972
124Hamartoma of the eye (HP:0010568)1.92479114
125Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.92472787
126Nephroblastoma (Wilms tumor) (HP:0002667)1.92402891
127Overlapping toe (HP:0001845)1.91518774
128Vomiting (HP:0002013)1.90772593
129Small intestinal stenosis (HP:0012848)1.89748099
130Duodenal stenosis (HP:0100867)1.89748099
131Neonatal death (HP:0003811)1.88800467
132CNS demyelination (HP:0007305)1.87556082
133Difficulty climbing stairs (HP:0003551)1.86909148
134Reticulocytosis (HP:0001923)1.86792417
135Neck muscle weakness (HP:0000467)1.86666922
136Abnormality of the labia minora (HP:0012880)1.85935578
137Abnormal atrioventricular conduction (HP:0005150)1.85736840
138Abnormality of the ileum (HP:0001549)1.85539294
139Increased purine levels (HP:0004368)1.84776347
140Hyperuricemia (HP:0002149)1.84776347
141Hyperglycinemia (HP:0002154)1.81754874
142Limb-girdle muscle atrophy (HP:0003797)1.80931057
143Aplasia/Hypoplasia of the uvula (HP:0010293)1.79202922
144Ependymoma (HP:0002888)1.77942050
145Pelvic girdle muscle weakness (HP:0003749)1.76293505
146Embryonal renal neoplasm (HP:0011794)1.75123430
147Proximal placement of thumb (HP:0009623)1.74220366
148Calcaneovalgus deformity (HP:0001848)1.71562286
149Neoplasm of the colon (HP:0100273)1.71306713
150Postnatal microcephaly (HP:0005484)1.64682038
151Abnormality of methionine metabolism (HP:0010901)1.63865023

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK34.86665858
2PDK44.86665858
3NEK14.29048453
4OBSCN4.20296837
5BCKDK3.47111877
6TTN3.43077260
7PDK23.12272432
8PKN22.76201380
9MYLK2.57506737
10LMTK22.50117148
11STK38L2.33169497
12ZAK2.30823157
13PIK3CA2.01560278
14STK241.98838861
15WEE11.97911051
16VRK21.97217222
17PHKG21.93946283
18PHKG11.93946283
19BRSK21.92625069
20CDC71.79297818
21WNK41.78403624
22BUB11.77098924
23TTK1.67902238
24FLT31.44353735
25TRIB31.38981313
26EIF2AK11.36206361
27CDK121.28531535
28TSSK61.27983937
29EEF2K1.27543211
30SMG11.26500222
31MAP3K121.25075694
32STK41.23471513
33MST1R1.22402995
34TIE11.17964944
35PNCK1.11807860
36BRAF1.07675050
37MST40.99600648
38PLK40.99453077
39ICK0.98925771
40TRIM280.95052302
41NEK90.94456894
42AURKB0.89925843
43PLK10.89274648
44PINK10.89162637
45PASK0.88629141
46EIF2AK30.87113224
47CLK10.86731446
48PLK30.84010674
49ILK0.80055571
50ALK0.79941599
51BRSK10.77977511
52ACVR1B0.76767445
53SRPK10.75498045
54TAF10.75405493
55NME10.75018921
56BRD40.74878240
57ATR0.74742026
58LATS10.74194029
59ARAF0.73152273
60MET0.72382600
61IRAK30.70134747
62TGFBR10.69483410
63NEK20.69125107
64CDK10.69015383
65WNK30.68577369
66DMPK0.67439474
67CDK190.67067375
68TRPM70.66392368
69CDK20.66144849
70PRKAA10.63391862
71DAPK10.62069801
72LIMK10.61823404
73CSNK1E0.61459380
74TESK10.60944522
75CDK90.60316907
76ERBB40.59916372
77CDK180.59727307
78CDK80.59408007
79CDK40.59321357
80MUSK0.59034887
81LATS20.58810365
82CDK11A0.58510055
83MAP3K100.58407080
84CDK150.57247861
85CCNB10.55997476
86PRKAA20.55667053
87CDK140.55517377
88SCYL20.55496789
89NME20.53983491
90STK390.53972915
91STK160.53774082
92MAP2K30.53559898
93KSR20.52452875
94KSR10.51815624
95STK30.51142295
96AKT20.51004975
97RPS6KB20.49685585
98CDK60.49286360
99MAP3K80.49256384
100CSNK1G30.48110615
101MAP3K50.48021660
102CAMK2D0.46644435
103CDC42BPA0.45922742
104MAP3K70.45465898
105TESK20.45179096
106MAPKAPK30.44124073
107PRKDC0.43933482
108RAF10.42769599
109OXSR10.41645496
110AURKA0.40781965
111ATM0.39882574
112CHEK10.39548894
113VRK10.38564715
114BCR0.37333964
115CSNK1A1L0.37316982
116WNK10.37118129
117PAK10.37070204
118CSNK1G10.36911841
119GRK70.35721776
120ROCK10.33315624
121STK100.33147210
122KDR0.32983603
123PAK40.32560259
124MKNK10.32267806
125DAPK30.32048294
126PRKACB0.31756054
127RPS6KA40.31337364
128PBK0.31174510
129ERBB30.30575432
130CSNK2A10.30005548
131AKT30.28286551
132MAP3K30.27144734
133CSNK2A20.26828556
134FGFR10.26389898
135PRKD10.26147132
136EIF2AK20.24642662
137PAK30.23512153
138STK380.23278581
139RPS6KC10.23092148
140RPS6KL10.23092148
141CDK70.23038099
142CHEK20.22426469
143MARK30.21870907
144RPS6KB10.19695409

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000206.27477585
22-Oxocarboxylic acid metabolism_Homo sapiens_hsa012104.51498700
3Propanoate metabolism_Homo sapiens_hsa006403.81223224
4Carbon metabolism_Homo sapiens_hsa012003.03494822
5Fatty acid degradation_Homo sapiens_hsa000712.83439840
6Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.77083520
7Pyruvate metabolism_Homo sapiens_hsa006202.66910971
8Parkinsons disease_Homo sapiens_hsa050122.66382513
9Oxidative phosphorylation_Homo sapiens_hsa001902.61317619
10Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.54747558
11Cardiac muscle contraction_Homo sapiens_hsa042602.38309527
12Fatty acid metabolism_Homo sapiens_hsa012122.33187970
13DNA replication_Homo sapiens_hsa030302.03502364
14Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.92949463
15Huntingtons disease_Homo sapiens_hsa050161.92149451
16Biosynthesis of amino acids_Homo sapiens_hsa012301.91500472
17Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.80283105
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.78213158
19Mismatch repair_Homo sapiens_hsa034301.69450897
20Alzheimers disease_Homo sapiens_hsa050101.68242405
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.65110298
22Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.62051536
23Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.57081938
24Proteasome_Homo sapiens_hsa030501.49686469
25One carbon pool by folate_Homo sapiens_hsa006701.47845011
26Fatty acid elongation_Homo sapiens_hsa000621.45098967
27Butanoate metabolism_Homo sapiens_hsa006501.43943196
28Dilated cardiomyopathy_Homo sapiens_hsa054141.41968000
29Steroid biosynthesis_Homo sapiens_hsa001001.35212017
30PPAR signaling pathway_Homo sapiens_hsa033201.21495693
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.18354097
32Protein export_Homo sapiens_hsa030601.15453618
33Cysteine and methionine metabolism_Homo sapiens_hsa002701.10059154
34Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.09641104
35RNA transport_Homo sapiens_hsa030131.07767294
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.06768735
37Homologous recombination_Homo sapiens_hsa034401.05270606
38beta-Alanine metabolism_Homo sapiens_hsa004100.97639151
39Peroxisome_Homo sapiens_hsa041460.96342744
40Tryptophan metabolism_Homo sapiens_hsa003800.92441086
41Fructose and mannose metabolism_Homo sapiens_hsa000510.90935078
42Base excision repair_Homo sapiens_hsa034100.89602135
43Starch and sucrose metabolism_Homo sapiens_hsa005000.89004786
44Vitamin B6 metabolism_Homo sapiens_hsa007500.88060439
45Sulfur relay system_Homo sapiens_hsa041220.88035686
46Nucleotide excision repair_Homo sapiens_hsa034200.86910393
47Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.86518512
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.84841065
49Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.84677240
50Galactose metabolism_Homo sapiens_hsa000520.82538159
51Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.82453648
52Pentose phosphate pathway_Homo sapiens_hsa000300.81328740
53Cell cycle_Homo sapiens_hsa041100.81150567
54Lysine degradation_Homo sapiens_hsa003100.81108890
55Cyanoamino acid metabolism_Homo sapiens_hsa004600.80126014
56Pyrimidine metabolism_Homo sapiens_hsa002400.80086090
57RNA polymerase_Homo sapiens_hsa030200.79995348
58Spliceosome_Homo sapiens_hsa030400.78420483
59Glutathione metabolism_Homo sapiens_hsa004800.71973803
60Glucagon signaling pathway_Homo sapiens_hsa049220.71576977
61Fatty acid biosynthesis_Homo sapiens_hsa000610.71450925
62Non-homologous end-joining_Homo sapiens_hsa034500.71084186
63Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.69298539
64RNA degradation_Homo sapiens_hsa030180.68452333
65Selenocompound metabolism_Homo sapiens_hsa004500.67436788
66Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.66152488
67Metabolic pathways_Homo sapiens_hsa011000.64944318
68Arginine and proline metabolism_Homo sapiens_hsa003300.61342284
69Phenylalanine metabolism_Homo sapiens_hsa003600.59253184
70Purine metabolism_Homo sapiens_hsa002300.57483845
71Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.57191202
72Central carbon metabolism in cancer_Homo sapiens_hsa052300.55666591
73Fanconi anemia pathway_Homo sapiens_hsa034600.53277531
74Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.53074956
75N-Glycan biosynthesis_Homo sapiens_hsa005100.52701939
76AMPK signaling pathway_Homo sapiens_hsa041520.52382619
77Glycerolipid metabolism_Homo sapiens_hsa005610.50715641
78Fat digestion and absorption_Homo sapiens_hsa049750.49813714
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.48388085
80Tyrosine metabolism_Homo sapiens_hsa003500.47308809
81HIF-1 signaling pathway_Homo sapiens_hsa040660.46520056
82Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.46474138
83Sulfur metabolism_Homo sapiens_hsa009200.45781156
84Arginine biosynthesis_Homo sapiens_hsa002200.43405590
85Viral myocarditis_Homo sapiens_hsa054160.42955028
86Adipocytokine signaling pathway_Homo sapiens_hsa049200.39731121
87Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.39656527
88Ribosome_Homo sapiens_hsa030100.39579776
89mRNA surveillance pathway_Homo sapiens_hsa030150.39383929
90Insulin resistance_Homo sapiens_hsa049310.38652723
91Insulin signaling pathway_Homo sapiens_hsa049100.38508183
92Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.35764766
93Drug metabolism - other enzymes_Homo sapiens_hsa009830.30287973
94Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.29510338
95Folate biosynthesis_Homo sapiens_hsa007900.27668057
96Tight junction_Homo sapiens_hsa045300.26232062
97Pentose and glucuronate interconversions_Homo sapiens_hsa000400.24083526
98Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.23861153
99Basal transcription factors_Homo sapiens_hsa030220.19154838
100Epstein-Barr virus infection_Homo sapiens_hsa051690.18505648
101Viral carcinogenesis_Homo sapiens_hsa052030.17657823
102Thyroid cancer_Homo sapiens_hsa052160.17631413
103Oocyte meiosis_Homo sapiens_hsa041140.17367355
104Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.16315192
105Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.15313032
106Systemic lupus erythematosus_Homo sapiens_hsa053220.14904855
107Renin-angiotensin system_Homo sapiens_hsa046140.12454559
108Adherens junction_Homo sapiens_hsa045200.11085574
109cGMP-PKG signaling pathway_Homo sapiens_hsa040220.10001972
110p53 signaling pathway_Homo sapiens_hsa041150.09825408
111Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.09457080
112Vitamin digestion and absorption_Homo sapiens_hsa049770.09199772
113Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.08612139
114Vibrio cholerae infection_Homo sapiens_hsa051100.07597077

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