

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of vitamin D biosynthetic process (GO:0060556) | 6.33162354 |
| 2 | regulation of podosome assembly (GO:0071801) | 5.43304347 |
| 3 | regulation of vitamin metabolic process (GO:0030656) | 5.01674716 |
| 4 | negative regulation of interleukin-12 production (GO:0032695) | 4.87876181 |
| 5 | positive regulation of chemokine biosynthetic process (GO:0045080) | 4.86018602 |
| 6 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 4.76059629 |
| 7 | defense response to protozoan (GO:0042832) | 4.63516630 |
| 8 | regulation of chemokine biosynthetic process (GO:0045073) | 4.43479279 |
| 9 | response to protozoan (GO:0001562) | 4.32489136 |
| 10 | response to peptidoglycan (GO:0032494) | 4.23285707 |
| 11 | myeloid dendritic cell differentiation (GO:0043011) | 4.15834738 |
| 12 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.09586321 |
| 13 | negative regulation of cell killing (GO:0031342) | 4.09586321 |
| 14 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.05923197 |
| 15 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 4.03847816 |
| 16 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 4.03847816 |
| 17 | macrophage activation involved in immune response (GO:0002281) | 4.00836190 |
| 18 | regulation of growth of symbiont in host (GO:0044126) | 3.91004249 |
| 19 | negative regulation of growth of symbiont in host (GO:0044130) | 3.91004249 |
| 20 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 3.91004249 |
| 21 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 3.91004249 |
| 22 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.89932004 |
| 23 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.88871060 |
| 24 | type I interferon signaling pathway (GO:0060337) | 3.83947086 |
| 25 | cellular response to type I interferon (GO:0071357) | 3.83947086 |
| 26 | myeloid dendritic cell activation (GO:0001773) | 3.83821964 |
| 27 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.83329940 |
| 28 | neutrophil activation involved in immune response (GO:0002283) | 3.79063574 |
| 29 | response to type I interferon (GO:0034340) | 3.78002901 |
| 30 | leukocyte aggregation (GO:0070486) | 3.76829473 |
| 31 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.73937968 |
| 32 | regulation of interleukin-12 production (GO:0032655) | 3.72681647 |
| 33 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.72212812 |
| 34 | modulation by symbiont of host immune response (GO:0052553) | 3.72212812 |
| 35 | positive regulation by symbiont of host defense response (GO:0052509) | 3.72212812 |
| 36 | modulation by symbiont of host defense response (GO:0052031) | 3.72212812 |
| 37 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.72212812 |
| 38 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.72212812 |
| 39 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 3.65277971 |
| 40 | regulation of interferon-alpha production (GO:0032647) | 3.64372366 |
| 41 | regulation of interleukin-1 beta secretion (GO:0050706) | 3.63825972 |
| 42 | negative regulation of interleukin-17 production (GO:0032700) | 3.59671448 |
| 43 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.59568883 |
| 44 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.57447226 |
| 45 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 3.57133810 |
| 46 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.54112739 |
| 47 | positive regulation of interleukin-12 production (GO:0032735) | 3.53263681 |
| 48 | immunoglobulin mediated immune response (GO:0016064) | 3.50088843 |
| 49 | regulation of chronic inflammatory response (GO:0002676) | 3.44817228 |
| 50 | positive regulation of type 2 immune response (GO:0002830) | 3.44739218 |
| 51 | positive regulation of isotype switching (GO:0045830) | 3.42265763 |
| 52 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.37998586 |
| 53 | positive regulation of interferon-alpha production (GO:0032727) | 3.35601087 |
| 54 | positive regulation of interleukin-1 secretion (GO:0050716) | 3.33943885 |
| 55 | germinal center formation (GO:0002467) | 3.31939026 |
| 56 | macrophage activation (GO:0042116) | 3.25873669 |
| 57 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.25353520 |
| 58 | response to interleukin-15 (GO:0070672) | 3.24028377 |
| 59 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.23764041 |
| 60 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.21887293 |
| 61 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.21887293 |
| 62 | regulation of interleukin-1 secretion (GO:0050704) | 3.21650856 |
| 63 | positive regulation of DNA recombination (GO:0045911) | 3.15687033 |
| 64 | regulation of regulatory T cell differentiation (GO:0045589) | 3.15147737 |
| 65 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 3.13762147 |
| 66 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.13759922 |
| 67 | regulation of T cell tolerance induction (GO:0002664) | 3.13211483 |
| 68 | cellular extravasation (GO:0045123) | 3.12846426 |
| 69 | regulation of T-helper cell differentiation (GO:0045622) | 3.12842538 |
| 70 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.11583745 |
| 71 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.09936970 |
| 72 | positive regulation of antigen processing and presentation (GO:0002579) | 3.08803389 |
| 73 | positive regulation of interleukin-10 production (GO:0032733) | 3.08118729 |
| 74 | dendritic cell differentiation (GO:0097028) | 3.08095271 |
| 75 | NIK/NF-kappaB signaling (GO:0038061) | 3.08039834 |
| 76 | regulation of interleukin-17 production (GO:0032660) | 3.07923237 |
| 77 | myeloid cell activation involved in immune response (GO:0002275) | 3.07899074 |
| 78 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.07804147 |
| 79 | positive regulation of B cell mediated immunity (GO:0002714) | 3.07804147 |
| 80 | granulocyte activation (GO:0036230) | 3.07118056 |
| 81 | positive regulation of heat generation (GO:0031652) | 3.04833736 |
| 82 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.03432210 |
| 83 | cellular response to interleukin-15 (GO:0071350) | 3.02979100 |
| 84 | tolerance induction (GO:0002507) | 3.02862344 |
| 85 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.02246137 |
| 86 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 3.01961345 |
| 87 | T cell activation involved in immune response (GO:0002286) | 3.00677181 |
| 88 | regulation of fever generation (GO:0031620) | 2.99333050 |
| 89 | positive regulation of defense response to virus by host (GO:0002230) | 2.99200936 |
| 90 | neutrophil activation (GO:0042119) | 2.98823161 |
| 91 | positive regulation of interleukin-6 production (GO:0032755) | 2.98473431 |
| 92 | regulation of antigen processing and presentation (GO:0002577) | 2.97986080 |
| 93 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.97287897 |
| 94 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.97005974 |
| 95 | detection of other organism (GO:0098543) | 2.96483791 |
| 96 | positive regulation of chemokine production (GO:0032722) | 2.96440197 |
| 97 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.95289578 |
| 98 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.95092506 |
| 99 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 2.93978385 |
| 100 | response to muramyl dipeptide (GO:0032495) | 2.93304213 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 7.08948973 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.18312040 |
| 3 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.95257747 |
| 4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.91203891 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.27025648 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.06552157 |
| 7 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.76681767 |
| 8 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.43851904 |
| 9 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 3.39533155 |
| 10 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.16557826 |
| 11 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.10860996 |
| 12 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.10537907 |
| 13 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.08207725 |
| 14 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.98990042 |
| 15 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.85677215 |
| 16 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.76147689 |
| 17 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.54525866 |
| 18 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.35092912 |
| 19 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.34017080 |
| 20 | MYB_26560356_Chip-Seq_TH2_Human | 2.33591289 |
| 21 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.31251544 |
| 22 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.21972139 |
| 23 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.21354278 |
| 24 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.99617514 |
| 25 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.99171969 |
| 26 | MAF_26560356_Chip-Seq_TH1_Human | 1.97881935 |
| 27 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.96911325 |
| 28 | MYB_26560356_Chip-Seq_TH1_Human | 1.85476888 |
| 29 | SPI1_23127762_ChIP-Seq_K562_Human | 1.84358727 |
| 30 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.81382113 |
| 31 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.78094845 |
| 32 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.72630755 |
| 33 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.66350219 |
| 34 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.60235643 |
| 35 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.59305847 |
| 36 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.57510182 |
| 37 | GATA3_26560356_Chip-Seq_TH2_Human | 1.54214302 |
| 38 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.53453386 |
| 39 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.52905128 |
| 40 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.51878817 |
| 41 | GATA1_22025678_ChIP-Seq_K562_Human | 1.51385254 |
| 42 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.50914636 |
| 43 | UTX_26944678_Chip-Seq_JUKART_Human | 1.43747867 |
| 44 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.42969318 |
| 45 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.41851321 |
| 46 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36516596 |
| 47 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.31643313 |
| 48 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.30925805 |
| 49 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.30315435 |
| 50 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.29691607 |
| 51 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28855951 |
| 52 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.24657391 |
| 53 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.23412256 |
| 54 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.21620723 |
| 55 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.20787873 |
| 56 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20736235 |
| 57 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.17510868 |
| 58 | MAF_26560356_Chip-Seq_TH2_Human | 1.17221015 |
| 59 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.16662595 |
| 60 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.16560907 |
| 61 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.14750971 |
| 62 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.13401830 |
| 63 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.08128778 |
| 64 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.07753012 |
| 65 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.07647569 |
| 66 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.04890892 |
| 67 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.03878811 |
| 68 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.03835491 |
| 69 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.99438316 |
| 70 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.99283927 |
| 71 | MYC_22102868_ChIP-Seq_BL_Human | 0.95963294 |
| 72 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.95650044 |
| 73 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.93312455 |
| 74 | GATA1_19941826_ChIP-Seq_K562_Human | 0.93185330 |
| 75 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.92932034 |
| 76 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.83294465 |
| 77 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.80227699 |
| 78 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.79541862 |
| 79 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.77124688 |
| 80 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.76875916 |
| 81 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.76376943 |
| 82 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.76176656 |
| 83 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.75792545 |
| 84 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.75239293 |
| 85 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.73627569 |
| 86 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.73345879 |
| 87 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.71507772 |
| 88 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.71387873 |
| 89 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.70682699 |
| 90 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.70593748 |
| 91 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.69770021 |
| 92 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.68560573 |
| 93 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.67768910 |
| 94 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.66756054 |
| 95 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.66030161 |
| 96 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.64391620 |
| 97 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.63753756 |
| 98 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.63650721 |
| 99 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.62479917 |
| 100 | GATA2_19941826_ChIP-Seq_K562_Human | 0.62442894 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 4.81954667 |
| 2 | MP0003303_peritoneal_inflammation | 4.52278610 |
| 3 | MP0003436_decreased_susceptibility_to | 4.01510852 |
| 4 | MP0005671_abnormal_response_to | 3.70223596 |
| 5 | MP0009785_altered_susceptibility_to | 3.63865100 |
| 6 | MP0002148_abnormal_hypersensitivity_rea | 3.58898451 |
| 7 | MP0003724_increased_susceptibility_to | 3.54475396 |
| 8 | MP0005000_abnormal_immune_tolerance | 3.20539910 |
| 9 | MP0005387_immune_system_phenotype | 3.13597160 |
| 10 | MP0001790_abnormal_immune_system | 3.13597160 |
| 11 | MP0006082_CNS_inflammation | 2.91969711 |
| 12 | MP0001800_abnormal_humoral_immune | 2.79958605 |
| 13 | MP0002419_abnormal_innate_immunity | 2.72118575 |
| 14 | MP0005025_abnormal_response_to | 2.63359007 |
| 15 | MP0002723_abnormal_immune_serum | 2.52719118 |
| 16 | MP0001873_stomach_inflammation | 2.51760950 |
| 17 | MP0002452_abnormal_antigen_presenting | 2.45404210 |
| 18 | MP0009333_abnormal_splenocyte_physiolog | 2.31122017 |
| 19 | MP0000685_abnormal_immune_system | 2.26625604 |
| 20 | MP0002420_abnormal_adaptive_immunity | 2.22315572 |
| 21 | MP0001819_abnormal_immune_cell | 2.21394838 |
| 22 | MP0010155_abnormal_intestine_physiology | 2.20983760 |
| 23 | MP0002405_respiratory_system_inflammati | 2.20522404 |
| 24 | MP0001533_abnormal_skeleton_physiology | 2.03992238 |
| 25 | MP0009764_decreased_sensitivity_to | 2.01735237 |
| 26 | MP0004510_myositis | 1.93595943 |
| 27 | MP0003300_gastrointestinal_ulcer | 1.87033663 |
| 28 | MP0001845_abnormal_inflammatory_respons | 1.86531402 |
| 29 | MP0004947_skin_inflammation | 1.79872639 |
| 30 | MP0005451_abnormal_body_composition | 1.79170432 |
| 31 | MP0008004_abnormal_stomach_pH | 1.75812392 |
| 32 | MP0001853_heart_inflammation | 1.68186618 |
| 33 | MP0008469_abnormal_protein_level | 1.65379428 |
| 34 | MP0002138_abnormal_hepatobiliary_system | 1.60822729 |
| 35 | MP0000716_abnormal_immune_system | 1.59221956 |
| 36 | MP0005310_abnormal_salivary_gland | 1.56822716 |
| 37 | MP0002398_abnormal_bone_marrow | 1.52363548 |
| 38 | MP0003448_altered_tumor_morphology | 1.51639428 |
| 39 | MP0003075_altered_response_to | 1.50310787 |
| 40 | MP0003763_abnormal_thymus_physiology | 1.47890901 |
| 41 | MP0005464_abnormal_platelet_physiology | 1.44705825 |
| 42 | MP0009278_abnormal_bone_marrow | 1.42353518 |
| 43 | MP0002332_abnormal_exercise_endurance | 1.40365231 |
| 44 | MP0003172_abnormal_lysosome_physiology | 1.35016184 |
| 45 | MP0009840_abnormal_foam_cell | 1.34910595 |
| 46 | MP0005166_decreased_susceptibility_to | 1.33783077 |
| 47 | MP0000689_abnormal_spleen_morphology | 1.33099182 |
| 48 | MP0002722_abnormal_immune_system | 1.27918017 |
| 49 | MP0003195_calcinosis | 1.27276672 |
| 50 | MP0005058_abnormal_lysosome_morphology | 1.26289765 |
| 51 | MP0002429_abnormal_blood_cell | 1.26257833 |
| 52 | MP0005167_abnormal_blood-brain_barrier | 1.24643425 |
| 53 | MP0000343_altered_response_to | 1.19711488 |
| 54 | MP0001545_abnormal_hematopoietic_system | 1.18772622 |
| 55 | MP0005397_hematopoietic_system_phenotyp | 1.18772622 |
| 56 | MP0001663_abnormal_digestive_system | 1.18520501 |
| 57 | MP0010307_abnormal_tumor_latency | 1.15381915 |
| 58 | MP0000858_altered_metastatic_potential | 1.12418695 |
| 59 | MP0002998_abnormal_bone_remodeling | 1.12262721 |
| 60 | MP0003866_abnormal_defecation | 1.11918749 |
| 61 | MP0002254_reproductive_system_inflammat | 1.09849983 |
| 62 | MP0009765_abnormal_xenobiotic_induced | 1.05340608 |
| 63 | MP0002933_joint_inflammation | 1.05335050 |
| 64 | MP0002139_abnormal_hepatobiliary_system | 1.04802878 |
| 65 | MP0002006_tumorigenesis | 1.04353674 |
| 66 | MP0003191_abnormal_cellular_cholesterol | 0.97259508 |
| 67 | MP0005390_skeleton_phenotype | 0.95030064 |
| 68 | MP0009763_increased_sensitivity_to | 0.93053450 |
| 69 | MP0001958_emphysema | 0.91001208 |
| 70 | MP0002166_altered_tumor_susceptibility | 0.89224974 |
| 71 | MP0003806_abnormal_nucleotide_metabolis | 0.89037032 |
| 72 | MP0005164_abnormal_response_to | 0.88019391 |
| 73 | MP0006054_spinal_hemorrhage | 0.87296756 |
| 74 | MP0000703_abnormal_thymus_morphology | 0.87203997 |
| 75 | MP0003656_abnormal_erythrocyte_physiolo | 0.84473656 |
| 76 | MP0000604_amyloidosis | 0.83716566 |
| 77 | MP0003453_abnormal_keratinocyte_physiol | 0.80828203 |
| 78 | MP0003091_abnormal_cell_migration | 0.79991485 |
| 79 | MP0004808_abnormal_hematopoietic_stem | 0.77791139 |
| 80 | MP0005165_increased_susceptibility_to | 0.76454541 |
| 81 | MP0001348_abnormal_lacrimal_gland | 0.75662701 |
| 82 | MP0000465_gastrointestinal_hemorrhage | 0.74369536 |
| 83 | MP0005381_digestive/alimentary_phenotyp | 0.73953999 |
| 84 | MP0003950_abnormal_plasma_membrane | 0.72533025 |
| 85 | MP0003045_fibrosis | 0.72177965 |
| 86 | MP0002277_abnormal_respiratory_mucosa | 0.70812136 |
| 87 | MP0003828_pulmonary_edema | 0.68501849 |
| 88 | MP0008260_abnormal_autophagy | 0.64938849 |
| 89 | MP0005319_abnormal_enzyme/_coenzyme | 0.64760605 |
| 90 | MP0004782_abnormal_surfactant_physiolog | 0.64627057 |
| 91 | MP0003646_muscle_fatigue | 0.63904237 |
| 92 | MP0003186_abnormal_redox_activity | 0.63785679 |
| 93 | MP0001542_abnormal_bone_strength | 0.61471076 |
| 94 | MP0002693_abnormal_pancreas_physiology | 0.60140447 |
| 95 | MP0003690_abnormal_glial_cell | 0.58901273 |
| 96 | MP0002132_abnormal_respiratory_system | 0.57515020 |
| 97 | MP0004883_abnormal_blood_vessel | 0.54558379 |
| 98 | MP0000249_abnormal_blood_vessel | 0.53239826 |
| 99 | MP0003795_abnormal_bone_structure | 0.52451652 |
| 100 | MP0004381_abnormal_hair_follicle | 0.52237794 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 6.09844276 |
| 2 | Optic neuritis (HP:0100653) | 5.54569238 |
| 3 | Retrobulbar optic neuritis (HP:0100654) | 5.54569238 |
| 4 | Myositis (HP:0100614) | 5.45292748 |
| 5 | Orchitis (HP:0100796) | 5.37757366 |
| 6 | Abnormality of macrophages (HP:0004311) | 4.89382309 |
| 7 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.66295326 |
| 8 | Recurrent bacterial skin infections (HP:0005406) | 4.57705166 |
| 9 | Abnormality of glycolipid metabolism (HP:0010969) | 4.39075029 |
| 10 | Abnormality of liposaccharide metabolism (HP:0010968) | 4.39075029 |
| 11 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 4.39075029 |
| 12 | Recurrent abscess formation (HP:0002722) | 4.34746629 |
| 13 | Eczematoid dermatitis (HP:0000976) | 4.09272847 |
| 14 | Pulmonary infiltrates (HP:0002113) | 3.97407514 |
| 15 | Increased IgM level (HP:0003496) | 3.87985689 |
| 16 | Keratoconjunctivitis sicca (HP:0001097) | 3.86194704 |
| 17 | T lymphocytopenia (HP:0005403) | 3.84755538 |
| 18 | Abnormality of T cell number (HP:0011839) | 3.80553605 |
| 19 | Mediastinal lymphadenopathy (HP:0100721) | 3.73443299 |
| 20 | Keratoconjunctivitis (HP:0001096) | 3.67530242 |
| 21 | Recurrent fungal infections (HP:0002841) | 3.62035057 |
| 22 | Vasculitis (HP:0002633) | 3.61711681 |
| 23 | Autoimmune thrombocytopenia (HP:0001973) | 3.60675027 |
| 24 | Gastrointestinal infarctions (HP:0005244) | 3.56283320 |
| 25 | Gangrene (HP:0100758) | 3.43771851 |
| 26 | Hemoptysis (HP:0002105) | 3.42694154 |
| 27 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.41812438 |
| 28 | Meningitis (HP:0001287) | 3.41403935 |
| 29 | Autoimmune hemolytic anemia (HP:0001890) | 3.37676671 |
| 30 | Encephalitis (HP:0002383) | 3.36569748 |
| 31 | Loss of speech (HP:0002371) | 3.19360916 |
| 32 | Recurrent viral infections (HP:0004429) | 3.18961300 |
| 33 | Obstructive lung disease (HP:0006536) | 3.17999382 |
| 34 | Chronic obstructive pulmonary disease (HP:0006510) | 3.17999382 |
| 35 | Increased serum ferritin (HP:0003281) | 3.04034102 |
| 36 | Chest pain (HP:0100749) | 2.99560509 |
| 37 | Recurrent skin infections (HP:0001581) | 2.96596587 |
| 38 | Abnormality of T cells (HP:0002843) | 2.95369331 |
| 39 | Arterial thrombosis (HP:0004420) | 2.91441590 |
| 40 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.88562723 |
| 41 | Vacuolated lymphocytes (HP:0001922) | 2.84875399 |
| 42 | Joint swelling (HP:0001386) | 2.82445120 |
| 43 | Abnormality of the pleura (HP:0002103) | 2.78059832 |
| 44 | Increased IgE level (HP:0003212) | 2.73475095 |
| 45 | Dysostosis multiplex (HP:0000943) | 2.71457504 |
| 46 | Leukocytosis (HP:0001974) | 2.70008947 |
| 47 | Polyneuropathy (HP:0001271) | 2.67824175 |
| 48 | Recurrent cutaneous fungal infections (HP:0011370) | 2.66317324 |
| 49 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.66317324 |
| 50 | Abnormality of iron homeostasis (HP:0011031) | 2.63696387 |
| 51 | Pustule (HP:0200039) | 2.63555882 |
| 52 | Pulmonary embolism (HP:0002204) | 2.61154366 |
| 53 | Increased cerebral lipofuscin (HP:0011813) | 2.53800948 |
| 54 | Hypergammaglobulinemia (HP:0010702) | 2.52827519 |
| 55 | Urticaria (HP:0001025) | 2.52313054 |
| 56 | Anorexia (HP:0002039) | 2.51247994 |
| 57 | Disinhibition (HP:0000734) | 2.42944074 |
| 58 | Abnormality of T cell physiology (HP:0011840) | 2.42764132 |
| 59 | IgA deficiency (HP:0002720) | 2.42292811 |
| 60 | Amyloidosis (HP:0011034) | 2.41713006 |
| 61 | Keratitis (HP:0000491) | 2.40904748 |
| 62 | IgG deficiency (HP:0004315) | 2.40614364 |
| 63 | Episodic fever (HP:0001954) | 2.33766080 |
| 64 | Arthralgia (HP:0002829) | 2.32924989 |
| 65 | Abnormality of the pericardium (HP:0001697) | 2.31753566 |
| 66 | Hepatosplenomegaly (HP:0001433) | 2.31589495 |
| 67 | Spontaneous hematomas (HP:0007420) | 2.30288745 |
| 68 | Panhypogammaglobulinemia (HP:0003139) | 2.26048782 |
| 69 | Epistaxis (HP:0000421) | 2.25348556 |
| 70 | Chronic diarrhea (HP:0002028) | 2.21598919 |
| 71 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.21507102 |
| 72 | Glomerulopathy (HP:0100820) | 2.20305963 |
| 73 | Abnormality of the prostate (HP:0008775) | 2.19808817 |
| 74 | Abnormality of B cell number (HP:0010975) | 2.19208534 |
| 75 | Amaurosis fugax (HP:0100576) | 2.18363382 |
| 76 | Hematochezia (HP:0002573) | 2.17360820 |
| 77 | Eosinophilia (HP:0001880) | 2.16159797 |
| 78 | Petechiae (HP:0000967) | 2.15169233 |
| 79 | Gingivitis (HP:0000230) | 2.14611840 |
| 80 | Acne (HP:0001061) | 2.12253484 |
| 81 | Gingival bleeding (HP:0000225) | 2.11382747 |
| 82 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.10955554 |
| 83 | Vertigo (HP:0002321) | 2.07907624 |
| 84 | Thrombophlebitis (HP:0004418) | 2.07145391 |
| 85 | B lymphocytopenia (HP:0010976) | 2.06822079 |
| 86 | Granulocytopenia (HP:0001913) | 2.06272931 |
| 87 | Recurrent bronchitis (HP:0002837) | 2.04280083 |
| 88 | Alveolar cell carcinoma (HP:0006519) | 2.03135081 |
| 89 | Mutism (HP:0002300) | 2.02712380 |
| 90 | Purpura (HP:0000979) | 2.01261394 |
| 91 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.00954836 |
| 92 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.00954836 |
| 93 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.00954836 |
| 94 | Systemic lupus erythematosus (HP:0002725) | 2.00376806 |
| 95 | Nausea (HP:0002018) | 1.97975794 |
| 96 | Interstitial pulmonary disease (HP:0006530) | 1.96562762 |
| 97 | Abnormality of the endocardium (HP:0004306) | 1.94375055 |
| 98 | Peritonitis (HP:0002586) | 1.93678351 |
| 99 | Lymphopenia (HP:0001888) | 1.93228704 |
| 100 | Parakeratosis (HP:0001036) | 1.93207914 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 5.43361098 |
| 2 | IRAK3 | 4.23906549 |
| 3 | MAP4K1 | 3.79470562 |
| 4 | RIPK4 | 3.19641239 |
| 5 | IRAK4 | 2.96695149 |
| 6 | GRK7 | 2.90400038 |
| 7 | BMPR2 | 2.77575639 |
| 8 | MAP3K14 | 2.70121350 |
| 9 | TYK2 | 2.62207892 |
| 10 | TBK1 | 2.43429287 |
| 11 | IKBKE | 2.28771802 |
| 12 | JAK3 | 2.27399425 |
| 13 | IKBKB | 2.22499676 |
| 14 | BLK | 2.17402626 |
| 15 | CSK | 2.03052056 |
| 16 | MATK | 2.01504195 |
| 17 | TAOK2 | 1.89431507 |
| 18 | ZAP70 | 1.73266816 |
| 19 | SIK3 | 1.73222599 |
| 20 | FGR | 1.65123409 |
| 21 | TAOK1 | 1.61628804 |
| 22 | MAP2K3 | 1.51247801 |
| 23 | KIT | 1.48718571 |
| 24 | NME2 | 1.47097826 |
| 25 | STK10 | 1.45580518 |
| 26 | JAK1 | 1.45116739 |
| 27 | ADRBK2 | 1.40571266 |
| 28 | MAP3K3 | 1.38867233 |
| 29 | PRPF4B | 1.35178696 |
| 30 | JAK2 | 1.33363409 |
| 31 | MAP3K11 | 1.32248133 |
| 32 | SYK | 1.29916181 |
| 33 | BTK | 1.26605436 |
| 34 | HCK | 1.21899842 |
| 35 | ACVR1B | 1.21345340 |
| 36 | DDR2 | 1.21195212 |
| 37 | IRAK1 | 1.14426809 |
| 38 | IRAK2 | 1.12556745 |
| 39 | MOS | 1.11521823 |
| 40 | TNK2 | 1.11057920 |
| 41 | LYN | 1.09908193 |
| 42 | MARK3 | 1.09710610 |
| 43 | LCK | 1.09195163 |
| 44 | CHUK | 1.06210545 |
| 45 | ERN1 | 1.05460241 |
| 46 | NME1 | 1.01863169 |
| 47 | CSF1R | 1.01151960 |
| 48 | RIPK1 | 1.00885792 |
| 49 | MAP3K13 | 0.98799828 |
| 50 | ITK | 0.96931492 |
| 51 | MUSK | 0.93541257 |
| 52 | FES | 0.91020394 |
| 53 | TEC | 0.88893314 |
| 54 | EIF2AK3 | 0.88376483 |
| 55 | CDC42BPA | 0.87457552 |
| 56 | TGFBR2 | 0.84456002 |
| 57 | MAP3K1 | 0.84298313 |
| 58 | TAOK3 | 0.81476761 |
| 59 | MST4 | 0.76543977 |
| 60 | TLK1 | 0.71918867 |
| 61 | TRPM7 | 0.69936486 |
| 62 | MAP3K5 | 0.69133263 |
| 63 | EPHB1 | 0.65587731 |
| 64 | PDK2 | 0.63513808 |
| 65 | PIM2 | 0.62933386 |
| 66 | PIM1 | 0.62018393 |
| 67 | GRK6 | 0.58724923 |
| 68 | MAP2K6 | 0.56811894 |
| 69 | TSSK6 | 0.54650929 |
| 70 | PRKCQ | 0.53567764 |
| 71 | MAPK11 | 0.53476989 |
| 72 | KSR2 | 0.52464748 |
| 73 | PDK1 | 0.45906094 |
| 74 | MAPK7 | 0.42789130 |
| 75 | ABL1 | 0.41590208 |
| 76 | EIF2AK2 | 0.40727901 |
| 77 | ABL2 | 0.36923311 |
| 78 | MAPKAPK2 | 0.33020434 |
| 79 | PDGFRB | 0.30853579 |
| 80 | MAP3K8 | 0.30469950 |
| 81 | CAMKK2 | 0.30439855 |
| 82 | MAPK12 | 0.28312924 |
| 83 | SIK2 | 0.28228586 |
| 84 | WNK1 | 0.27693553 |
| 85 | STK24 | 0.27340443 |
| 86 | CDK4 | 0.25396837 |
| 87 | PDPK1 | 0.25184264 |
| 88 | FGFR4 | 0.24295704 |
| 89 | PRKCD | 0.23574440 |
| 90 | MAPK4 | 0.21814542 |
| 91 | DAPK2 | 0.20035651 |
| 92 | MAPKAPK3 | 0.19170586 |
| 93 | RPS6KA6 | 0.19052241 |
| 94 | RPS6KL1 | 0.18819383 |
| 95 | RPS6KC1 | 0.18819383 |
| 96 | MAP3K12 | 0.18818590 |
| 97 | PKN1 | 0.18520850 |
| 98 | HIPK2 | 0.17955755 |
| 99 | TESK2 | 0.17843558 |
| 100 | FYN | 0.17141520 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.67939918 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.67456486 |
| 3 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.99297870 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.90572772 |
| 5 | Leishmaniasis_Homo sapiens_hsa05140 | 2.79568376 |
| 6 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.79089640 |
| 7 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.70427234 |
| 8 | Asthma_Homo sapiens_hsa05310 | 2.64216527 |
| 9 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.49285260 |
| 10 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.46843877 |
| 11 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.43852330 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.27277608 |
| 13 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.25642008 |
| 14 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.22840503 |
| 15 | Malaria_Homo sapiens_hsa05144 | 2.20031706 |
| 16 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.12797107 |
| 17 | TNF signaling pathway_Homo sapiens_hsa04668 | 2.11732769 |
| 18 | African trypanosomiasis_Homo sapiens_hsa05143 | 2.07201212 |
| 19 | Measles_Homo sapiens_hsa05162 | 2.01251450 |
| 20 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.93093067 |
| 21 | Tuberculosis_Homo sapiens_hsa05152 | 1.92827598 |
| 22 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.88331561 |
| 23 | Influenza A_Homo sapiens_hsa05164 | 1.87486870 |
| 24 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.86337224 |
| 25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.82654618 |
| 26 | Legionellosis_Homo sapiens_hsa05134 | 1.81556940 |
| 27 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.80325738 |
| 28 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.73608356 |
| 29 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.67743263 |
| 30 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.65877518 |
| 31 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.63801825 |
| 32 | Salmonella infection_Homo sapiens_hsa05132 | 1.63458537 |
| 33 | Pertussis_Homo sapiens_hsa05133 | 1.54681754 |
| 34 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.54225073 |
| 35 | Viral myocarditis_Homo sapiens_hsa05416 | 1.46179936 |
| 36 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.38760718 |
| 37 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.36877004 |
| 38 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.26324871 |
| 39 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.25340470 |
| 40 | Other glycan degradation_Homo sapiens_hsa00511 | 1.19736891 |
| 41 | Hepatitis B_Homo sapiens_hsa05161 | 1.04344622 |
| 42 | Lysosome_Homo sapiens_hsa04142 | 1.00129454 |
| 43 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.96947031 |
| 44 | Hepatitis C_Homo sapiens_hsa05160 | 0.95488114 |
| 45 | Amoebiasis_Homo sapiens_hsa05146 | 0.94206490 |
| 46 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.93299740 |
| 47 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.88137310 |
| 48 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.86417120 |
| 49 | Apoptosis_Homo sapiens_hsa04210 | 0.85899584 |
| 50 | Shigellosis_Homo sapiens_hsa05131 | 0.85736149 |
| 51 | Phagosome_Homo sapiens_hsa04145 | 0.77286710 |
| 52 | Proteasome_Homo sapiens_hsa03050 | 0.77224169 |
| 53 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.71921883 |
| 54 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.71475198 |
| 55 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.70059445 |
| 56 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.69060955 |
| 57 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67893425 |
| 58 | HTLV-I infection_Homo sapiens_hsa05166 | 0.64757008 |
| 59 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.61002839 |
| 60 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.60605236 |
| 61 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.57701349 |
| 62 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.52735859 |
| 63 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.51489076 |
| 64 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.50741292 |
| 65 | Platelet activation_Homo sapiens_hsa04611 | 0.46811681 |
| 66 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.45850040 |
| 67 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.44855108 |
| 68 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.44202349 |
| 69 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.44200819 |
| 70 | Bladder cancer_Homo sapiens_hsa05219 | 0.41278812 |
| 71 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.38750477 |
| 72 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.38471104 |
| 73 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.38053024 |
| 74 | Prion diseases_Homo sapiens_hsa05020 | 0.34558047 |
| 75 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.31175568 |
| 76 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.30413992 |
| 77 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.29487425 |
| 78 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.28483685 |
| 79 | Endocytosis_Homo sapiens_hsa04144 | 0.25922563 |
| 80 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.24137334 |
| 81 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.23852464 |
| 82 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.23796879 |
| 83 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.23394415 |
| 84 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.22323109 |
| 85 | Insulin resistance_Homo sapiens_hsa04931 | 0.21610473 |
| 86 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.20305092 |
| 87 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.20010699 |
| 88 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.16699958 |
| 89 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.14215439 |
| 90 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.14073893 |
| 91 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.12879713 |
| 92 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.11205047 |
| 93 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.11143348 |
| 94 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.07826200 |
| 95 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.06248137 |
| 96 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.04674221 |
| 97 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.03583323 |
| 98 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.02377896 |
| 99 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.00487755 |
| 100 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.00290353 |

