Rank | Gene Set | Z-score |
---|---|---|
1 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 7.48524390 |
2 | L-phenylalanine catabolic process (GO:0006559) | 7.48524390 |
3 | L-phenylalanine metabolic process (GO:0006558) | 7.16078599 |
4 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 7.16078599 |
5 | exogenous drug catabolic process (GO:0042738) | 6.88659703 |
6 | aromatic amino acid family catabolic process (GO:0009074) | 6.74883551 |
7 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 6.58937826 |
8 | tryptophan catabolic process (GO:0006569) | 6.10201817 |
9 | indole-containing compound catabolic process (GO:0042436) | 6.10201817 |
10 | indolalkylamine catabolic process (GO:0046218) | 6.10201817 |
11 | epoxygenase P450 pathway (GO:0019373) | 6.07647397 |
12 | kynurenine metabolic process (GO:0070189) | 6.04284639 |
13 | bile acid biosynthetic process (GO:0006699) | 6.01053244 |
14 | omega-hydroxylase P450 pathway (GO:0097267) | 5.92897862 |
15 | alpha-linolenic acid metabolic process (GO:0036109) | 5.89380012 |
16 | glyoxylate metabolic process (GO:0046487) | 5.78124400 |
17 | tryptophan metabolic process (GO:0006568) | 5.75010091 |
18 | high-density lipoprotein particle remodeling (GO:0034375) | 5.63248820 |
19 | negative regulation of fibrinolysis (GO:0051918) | 5.59508069 |
20 | urea metabolic process (GO:0019627) | 5.57998231 |
21 | urea cycle (GO:0000050) | 5.57998231 |
22 | regulation of fibrinolysis (GO:0051917) | 5.42754902 |
23 | peptidyl-glutamic acid carboxylation (GO:0017187) | 5.38779069 |
24 | protein carboxylation (GO:0018214) | 5.38779069 |
25 | regulation of protein activation cascade (GO:2000257) | 5.33587619 |
26 | regulation of plasminogen activation (GO:0010755) | 5.29473550 |
27 | complement activation, alternative pathway (GO:0006957) | 5.29282391 |
28 | sulfur amino acid catabolic process (GO:0000098) | 5.19657112 |
29 | cysteine metabolic process (GO:0006534) | 5.18201968 |
30 | bile acid metabolic process (GO:0008206) | 5.14400467 |
31 | nitrogen cycle metabolic process (GO:0071941) | 5.13059550 |
32 | serine family amino acid catabolic process (GO:0009071) | 5.08063411 |
33 | oxidative demethylation (GO:0070989) | 5.05729258 |
34 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 5.01265030 |
35 | regulation of triglyceride catabolic process (GO:0010896) | 4.98554524 |
36 | regulation of complement activation (GO:0030449) | 4.95772096 |
37 | reverse cholesterol transport (GO:0043691) | 4.95416550 |
38 | regulation of cholesterol esterification (GO:0010872) | 4.94382360 |
39 | aromatic amino acid family metabolic process (GO:0009072) | 4.90638095 |
40 | plasma lipoprotein particle remodeling (GO:0034369) | 4.84642167 |
41 | protein-lipid complex remodeling (GO:0034368) | 4.84642167 |
42 | macromolecular complex remodeling (GO:0034367) | 4.84642167 |
43 | drug metabolic process (GO:0017144) | 4.83037238 |
44 | tyrosine metabolic process (GO:0006570) | 4.73568541 |
45 | acylglycerol homeostasis (GO:0055090) | 4.70872946 |
46 | triglyceride homeostasis (GO:0070328) | 4.70872946 |
47 | phospholipid efflux (GO:0033700) | 4.70316245 |
48 | amino-acid betaine metabolic process (GO:0006577) | 4.67025218 |
49 | cellular ketone body metabolic process (GO:0046950) | 4.66818929 |
50 | negative regulation of cholesterol transport (GO:0032375) | 4.66755176 |
51 | negative regulation of sterol transport (GO:0032372) | 4.66755176 |
52 | negative regulation of hemostasis (GO:1900047) | 4.63561253 |
53 | negative regulation of blood coagulation (GO:0030195) | 4.63561253 |
54 | alpha-amino acid catabolic process (GO:1901606) | 4.61173423 |
55 | homocysteine metabolic process (GO:0050667) | 4.58050960 |
56 | lysine metabolic process (GO:0006553) | 4.57663578 |
57 | lysine catabolic process (GO:0006554) | 4.57663578 |
58 | L-serine metabolic process (GO:0006563) | 4.52978381 |
59 | coenzyme catabolic process (GO:0009109) | 4.45323727 |
60 | intestinal cholesterol absorption (GO:0030299) | 4.43414959 |
61 | glycine metabolic process (GO:0006544) | 4.42851489 |
62 | bile acid and bile salt transport (GO:0015721) | 4.41493740 |
63 | plasma lipoprotein particle clearance (GO:0034381) | 4.40883047 |
64 | indolalkylamine metabolic process (GO:0006586) | 4.32519546 |
65 | phenylpropanoid metabolic process (GO:0009698) | 4.31879285 |
66 | imidazole-containing compound metabolic process (GO:0052803) | 4.29251012 |
67 | cholesterol efflux (GO:0033344) | 4.28253880 |
68 | cellular glucuronidation (GO:0052695) | 4.28225790 |
69 | regulation of lipoprotein particle clearance (GO:0010984) | 4.27932789 |
70 | cellular amino acid catabolic process (GO:0009063) | 4.23600250 |
71 | glutamate metabolic process (GO:0006536) | 4.22560144 |
72 | cellular biogenic amine catabolic process (GO:0042402) | 4.22139019 |
73 | amine catabolic process (GO:0009310) | 4.22139019 |
74 | negative regulation of coagulation (GO:0050819) | 4.21625512 |
75 | negative regulation of wound healing (GO:0061045) | 4.16516685 |
76 | regulation of humoral immune response (GO:0002920) | 4.16287135 |
77 | serine family amino acid metabolic process (GO:0009069) | 4.14308792 |
78 | acute-phase response (GO:0006953) | 4.09479231 |
79 | ethanol oxidation (GO:0006069) | 4.08485826 |
80 | benzene-containing compound metabolic process (GO:0042537) | 4.05940142 |
81 | dicarboxylic acid biosynthetic process (GO:0043650) | 4.04515706 |
82 | ketone body metabolic process (GO:1902224) | 4.04284666 |
83 | low-density lipoprotein particle remodeling (GO:0034374) | 4.01761617 |
84 | fibrinolysis (GO:0042730) | 4.01170502 |
85 | plasma lipoprotein particle assembly (GO:0034377) | 4.00360624 |
86 | cellular modified amino acid catabolic process (GO:0042219) | 4.00003414 |
87 | arginine metabolic process (GO:0006525) | 3.98256490 |
88 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.97625792 |
89 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.97625792 |
90 | negative regulation of protein activation cascade (GO:2000258) | 3.97261315 |
91 | aldehyde catabolic process (GO:0046185) | 3.97096243 |
92 | serine family amino acid biosynthetic process (GO:0009070) | 3.94253299 |
93 | drug catabolic process (GO:0042737) | 3.88976171 |
94 | positive regulation of lipid catabolic process (GO:0050996) | 3.87685954 |
95 | blood coagulation, intrinsic pathway (GO:0007597) | 3.87003965 |
96 | regulation of apoptotic cell clearance (GO:2000425) | 3.83196707 |
97 | cofactor catabolic process (GO:0051187) | 3.79628993 |
98 | glucuronate metabolic process (GO:0019585) | 3.79594227 |
99 | uronic acid metabolic process (GO:0006063) | 3.79594227 |
100 | negative regulation of lipase activity (GO:0060192) | 3.78922608 |
101 | complement activation, classical pathway (GO:0006958) | 3.78364990 |
102 | S-adenosylmethionine metabolic process (GO:0046500) | 3.78030413 |
103 | cholesterol homeostasis (GO:0042632) | 3.76032383 |
104 | positive regulation of hemostasis (GO:1900048) | 3.75790376 |
105 | positive regulation of blood coagulation (GO:0030194) | 3.75790376 |
106 | phospholipid homeostasis (GO:0055091) | 3.75279623 |
107 | regulation of bile acid biosynthetic process (GO:0070857) | 3.74900609 |
108 | organic acid catabolic process (GO:0016054) | 3.73850877 |
109 | carboxylic acid catabolic process (GO:0046395) | 3.73850877 |
110 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.73746462 |
111 | heme transport (GO:0015886) | 3.73137200 |
112 | protein activation cascade (GO:0072376) | 3.72811649 |
113 | complement activation (GO:0006956) | 3.72783967 |
114 | regulation of cholesterol homeostasis (GO:2000188) | 3.72128643 |
115 | proline metabolic process (GO:0006560) | 3.72046566 |
116 | cytolysis (GO:0019835) | 3.70843392 |
117 | sterol homeostasis (GO:0055092) | 3.69756470 |
118 | alkaloid metabolic process (GO:0009820) | 3.69609095 |
119 | plasma lipoprotein particle organization (GO:0071827) | 3.67150079 |
120 | short-chain fatty acid metabolic process (GO:0046459) | 3.66050593 |
121 | acetyl-CoA metabolic process (GO:0006084) | 3.63981433 |
122 | flavonoid metabolic process (GO:0009812) | 3.61429089 |
123 | protein-lipid complex assembly (GO:0065005) | 3.58849642 |
124 | ethanol metabolic process (GO:0006067) | 3.58676619 |
125 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.58435558 |
126 | opsonization (GO:0008228) | 3.53929217 |
127 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 3.52589926 |
128 | peptidyl-glutamic acid modification (GO:0018200) | 3.42431924 |
129 | positive regulation of coagulation (GO:0050820) | 3.40155638 |
130 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 3.34645002 |
131 | protein-lipid complex subunit organization (GO:0071825) | 3.33284900 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 8.43091790 |
2 | * PPARA_22158963_ChIP-Seq_LIVER_Mouse | 7.23209283 |
3 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 7.02832342 |
4 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 6.50661585 |
5 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 5.31330846 |
6 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 5.07567831 |
7 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.92670460 |
8 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 4.05822654 |
9 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 3.98463775 |
10 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.21417223 |
11 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 2.05523421 |
12 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.01106978 |
13 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 11.9956659 |
14 | * HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.91337885 |
15 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.68856456 |
16 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.60691725 |
17 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.55404360 |
18 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.52313942 |
19 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.49347302 |
20 | GATA1_22025678_ChIP-Seq_K562_Human | 1.47180204 |
21 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.39721504 |
22 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.31277985 |
23 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21242914 |
24 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.19985128 |
25 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.18721261 |
26 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.18219978 |
27 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.16015556 |
28 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.10885183 |
29 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.02407917 |
30 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.01822003 |
31 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.01329879 |
32 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.01083882 |
33 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.99448161 |
34 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.94283664 |
35 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.94087620 |
36 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.92835684 |
37 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.92204227 |
38 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.91540398 |
39 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.89992808 |
40 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.89932715 |
41 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.89558223 |
42 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.88867503 |
43 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.88512080 |
44 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.88277333 |
45 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.85889089 |
46 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.85311959 |
47 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.85052643 |
48 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.84835404 |
49 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.84308451 |
50 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.83892683 |
51 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.82521362 |
52 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.82149048 |
53 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.81329587 |
54 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.80890243 |
55 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.80196484 |
56 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.80181701 |
57 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.79638212 |
58 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.79509022 |
59 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.79256348 |
60 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.78121493 |
61 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.77778157 |
62 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.77203874 |
63 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.77181010 |
64 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.77149620 |
65 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.75952392 |
66 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.75641909 |
67 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.75597075 |
68 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.75051566 |
69 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.74869271 |
70 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.74423482 |
71 | ERA_21632823_ChIP-Seq_H3396_Human | 0.74362149 |
72 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.73949063 |
73 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.73474486 |
74 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.73128598 |
75 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.73128598 |
76 | NFYA_21822215_ChIP-Seq_K562_Human | 0.72989356 |
77 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.72838411 |
78 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.72667191 |
79 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.72028004 |
80 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.71945254 |
81 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.71531246 |
82 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.70694920 |
83 | * GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.70114187 |
84 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.69689357 |
85 | SA1_27219007_Chip-Seq_Bcells_Human | 0.69290710 |
86 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.68686954 |
87 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.68532486 |
88 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.66363609 |
89 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.66351926 |
90 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.66237697 |
91 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.65922370 |
92 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.65806249 |
93 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.65525021 |
94 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.65145533 |
95 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.64787683 |
96 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.63766932 |
97 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.63766932 |
98 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.63749630 |
99 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.63160849 |
100 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.62683616 |
101 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.62517102 |
102 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.62165436 |
103 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.61940568 |
104 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.61918412 |
105 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.61758654 |
106 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.61034891 |
107 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.60851669 |
108 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.60622996 |
109 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.60609076 |
110 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.60064015 |
111 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.59958733 |
112 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.59958733 |
113 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.59776295 |
114 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.59413492 |
115 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.58960523 |
116 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.57596486 |
117 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.55825380 |
118 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.53107004 |
119 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.52987578 |
120 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.52357692 |
121 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.52156209 |
122 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.51298148 |
123 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.50936225 |
124 | AR_20517297_ChIP-Seq_VCAP_Human | 0.50840093 |
125 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.50111758 |
126 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.49594816 |
127 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.49267822 |
128 | CBP_21632823_ChIP-Seq_H3396_Human | 0.49235369 |
129 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.48749601 |
130 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.48644871 |
131 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.47020024 |
132 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.46961454 |
133 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.45861779 |
134 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.45323374 |
135 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.45265949 |
136 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.44326468 |
137 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.41978728 |
138 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.41297016 |
139 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.41161138 |
140 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.41156937 |
141 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.40920379 |
142 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.40842490 |
143 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.40819637 |
144 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.40666737 |
145 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.40420456 |
146 | GATA1_19941826_ChIP-Seq_K562_Human | 0.40118852 |
147 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.39281290 |
148 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.39215130 |
149 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.38918152 |
150 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.38856585 |
151 | GATA2_19941826_ChIP-Seq_K562_Human | 0.38406896 |
152 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.38032541 |
153 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.37580374 |
154 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.36763810 |
155 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.36095228 |
156 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 0.33794472 |
157 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.33506227 |
158 | NCOR_22424771_ChIP-Seq_293T_Human | 0.33491612 |
159 | * LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 0.33351463 |
160 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.33226308 |
161 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.33203664 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 8.43877677 |
2 | MP0005360_urolithiasis | 7.42912937 |
3 | MP0005085_abnormal_gallbladder_physiolo | 6.48216727 |
4 | MP0005365_abnormal_bile_salt | 6.19943121 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 5.20116317 |
6 | MP0003806_abnormal_nucleotide_metabolis | 4.26091779 |
7 | MP0003252_abnormal_bile_duct | 3.95448892 |
8 | MP0010329_abnormal_lipoprotein_level | 3.62460152 |
9 | MP0009840_abnormal_foam_cell | 3.36692906 |
10 | MP0005083_abnormal_biliary_tract | 3.14096707 |
11 | MP0003195_calcinosis | 2.76985671 |
12 | MP0005332_abnormal_amino_acid | 2.72240901 |
13 | MP0001666_abnormal_nutrient_absorption | 2.60158423 |
14 | MP0003191_abnormal_cellular_cholesterol | 2.32506901 |
15 | MP0000609_abnormal_liver_physiology | 2.17817417 |
16 | MP0002118_abnormal_lipid_homeostasis | 2.12684348 |
17 | MP0004019_abnormal_vitamin_homeostasis | 2.09392372 |
18 | MP0003868_abnormal_feces_composition | 1.95225997 |
19 | MP0002138_abnormal_hepatobiliary_system | 1.93142720 |
20 | MP0005319_abnormal_enzyme/_coenzyme | 1.82456040 |
21 | MP0009697_abnormal_copulation | 1.61239766 |
22 | MP0001764_abnormal_homeostasis | 1.60255133 |
23 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.55335545 |
24 | MP0000566_synostosis | 1.52858289 |
25 | MP0005451_abnormal_body_composition | 1.52644951 |
26 | MP0003011_delayed_dark_adaptation | 1.40948508 |
27 | MP0003656_abnormal_erythrocyte_physiolo | 1.25255517 |
28 | MP0003186_abnormal_redox_activity | 1.22650072 |
29 | MP0005647_abnormal_sex_gland | 1.19546288 |
30 | MP0009643_abnormal_urine_homeostasis | 1.19063672 |
31 | MP0000598_abnormal_liver_morphology | 1.17020637 |
32 | MP0003646_muscle_fatigue | 1.15638288 |
33 | MP0003122_maternal_imprinting | 1.11501191 |
34 | MP0003705_abnormal_hypodermis_morpholog | 1.11143561 |
35 | MP0000604_amyloidosis | 1.10188533 |
36 | MP0009764_decreased_sensitivity_to | 1.07927418 |
37 | MP0002254_reproductive_system_inflammat | 1.02977721 |
38 | MP0009763_increased_sensitivity_to | 1.01457085 |
39 | MP0006292_abnormal_olfactory_placode | 0.96686579 |
40 | MP0010368_abnormal_lymphatic_system | 0.95484712 |
41 | MP0003136_yellow_coat_color | 0.93072096 |
42 | MP0005646_abnormal_pituitary_gland | 0.91534025 |
43 | MP0005636_abnormal_mineral_homeostasis | 0.89291725 |
44 | MP0005645_abnormal_hypothalamus_physiol | 0.89158690 |
45 | MP0005187_abnormal_penis_morphology | 0.88392336 |
46 | MP0008469_abnormal_protein_level | 0.87722613 |
47 | MP0009642_abnormal_blood_homeostasis | 0.86426974 |
48 | MP0006036_abnormal_mitochondrial_physio | 0.81694977 |
49 | MP0005408_hypopigmentation | 0.80968115 |
50 | MP0001915_intracranial_hemorrhage | 0.80451872 |
51 | MP0003890_abnormal_embryonic-extraembry | 0.79168264 |
52 | MP0005670_abnormal_white_adipose | 0.78801539 |
53 | MP0002876_abnormal_thyroid_physiology | 0.78753221 |
54 | MP0002078_abnormal_glucose_homeostasis | 0.78730268 |
55 | MP0005376_homeostasis/metabolism_phenot | 0.77740875 |
56 | MP0009765_abnormal_xenobiotic_induced | 0.77605452 |
57 | MP0005084_abnormal_gallbladder_morpholo | 0.74121999 |
58 | MP0002089_abnormal_postnatal_growth/wei | 0.73676870 |
59 | MP0004130_abnormal_muscle_cell | 0.73512431 |
60 | MP0002971_abnormal_brown_adipose | 0.71194658 |
61 | MP0003567_abnormal_fetal_cardiomyocyte | 0.70919412 |
62 | MP0005334_abnormal_fat_pad | 0.70431156 |
63 | MP0003690_abnormal_glial_cell | 0.69217659 |
64 | MP0005220_abnormal_exocrine_pancreas | 0.68470761 |
65 | MP0005379_endocrine/exocrine_gland_phen | 0.68032107 |
66 | MP0005535_abnormal_body_temperature | 0.66722624 |
67 | MP0005266_abnormal_metabolism | 0.64861822 |
68 | MP0001661_extended_life_span | 0.64780042 |
69 | MP0003329_amyloid_beta_deposits | 0.64564467 |
70 | MP0005551_abnormal_eye_electrophysiolog | 0.63912212 |
71 | MP0009053_abnormal_anal_canal | 0.63154436 |
72 | MP0002282_abnormal_trachea_morphology | 0.63040813 |
73 | MP0003941_abnormal_skin_development | 0.62302898 |
74 | MP0000639_abnormal_adrenal_gland | 0.59954406 |
75 | MP0002249_abnormal_larynx_morphology | 0.59805073 |
76 | MP0006035_abnormal_mitochondrial_morpho | 0.58827605 |
77 | MP0003959_abnormal_lean_body | 0.56485973 |
78 | MP0005448_abnormal_energy_balance | 0.55883573 |
79 | MP0001756_abnormal_urination | 0.55654287 |
80 | MP0004133_heterotaxia | 0.55164163 |
81 | MP0003693_abnormal_embryo_hatching | 0.53470089 |
82 | MP0001293_anophthalmia | 0.52866276 |
83 | MP0005464_abnormal_platelet_physiology | 0.52400906 |
84 | MP0002697_abnormal_eye_size | 0.52243193 |
85 | MP0004233_abnormal_muscle_weight | 0.51333003 |
86 | MP0002822_catalepsy | 0.49345776 |
87 | MP0004142_abnormal_muscle_tone | 0.48599011 |
88 | MP0005395_other_phenotype | 0.48421215 |
89 | MP0008007_abnormal_cellular_replicative | 0.48371773 |
90 | MP0010030_abnormal_orbit_morphology | 0.48105984 |
91 | MP0005377_hearing/vestibular/ear_phenot | 0.47304849 |
92 | MP0003878_abnormal_ear_physiology | 0.47304849 |
93 | MP0008874_decreased_physiological_sensi | 0.46767140 |
94 | MP0005410_abnormal_fertilization | 0.46758711 |
95 | MP0003638_abnormal_response/metabolism_ | 0.46440303 |
96 | MP0003718_maternal_effect | 0.46240255 |
97 | MP0004782_abnormal_surfactant_physiolog | 0.46118837 |
98 | MP0002837_dystrophic_cardiac_calcinosis | 0.44727733 |
99 | MP0005248_abnormal_Harderian_gland | 0.44148244 |
100 | MP0002928_abnormal_bile_duct | 0.43530313 |
101 | MP0008873_increased_physiological_sensi | 0.42756606 |
102 | MP0002136_abnormal_kidney_physiology | 0.42463948 |
103 | MP0003953_abnormal_hormone_level | 0.40903843 |
104 | MP0001324_abnormal_eye_pigmentation | 0.40534742 |
105 | MP0003436_decreased_susceptibility_to | 0.39904374 |
106 | MP0003075_altered_response_to | 0.39689836 |
107 | MP0001944_abnormal_pancreas_morphology | 0.38866023 |
108 | MP0003724_increased_susceptibility_to | 0.38765892 |
109 | MP0001529_abnormal_vocalization | 0.38655145 |
110 | MP0005666_abnormal_adipose_tissue | 0.38379301 |
111 | MP0005166_decreased_susceptibility_to | 0.37524906 |
112 | MP0003879_abnormal_hair_cell | 0.37489378 |
113 | MP0004381_abnormal_hair_follicle | 0.36970992 |
114 | MP0008872_abnormal_physiological_respon | 0.36882017 |
115 | MP0000579_abnormal_nail_morphology | 0.36640479 |
116 | MP0003937_abnormal_limbs/digits/tail_de | 0.35894578 |
117 | MP0003943_abnormal_hepatobiliary_system | 0.35381684 |
118 | MP0003119_abnormal_digestive_system | 0.35334961 |
119 | MP0002938_white_spotting | 0.35222988 |
120 | MP0003699_abnormal_female_reproductive | 0.35156088 |
121 | MP0009672_abnormal_birth_weight | 0.33300229 |
122 | MP0009115_abnormal_fat_cell | 0.32994540 |
123 | MP0006082_CNS_inflammation | 0.32834057 |
124 | MP0001853_heart_inflammation | 0.31409861 |
125 | MP0001243_abnormal_dermal_layer | 0.31326998 |
126 | MP0000249_abnormal_blood_vessel | 0.31005344 |
127 | MP0002796_impaired_skin_barrier | 0.30804805 |
128 | MP0000230_abnormal_systemic_arterial | 0.30762654 |
129 | MP0002970_abnormal_white_adipose | 0.30386866 |
130 | MP0004883_abnormal_blood_vessel | 0.30300130 |
131 | MP0002168_other_aberrant_phenotype | 0.29630204 |
132 | MP0009384_cardiac_valve_regurgitation | 0.28943667 |
133 | MP0001881_abnormal_mammary_gland | 0.27650860 |
134 | MP0001845_abnormal_inflammatory_respons | 0.26217012 |
135 | MP0002132_abnormal_respiratory_system | 0.24956654 |
136 | MP0005164_abnormal_response_to | 0.23239677 |
137 | MP0002060_abnormal_skin_morphology | 0.22758820 |
138 | MP0000427_abnormal_hair_cycle | 0.22469210 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Deep venous thrombosis (HP:0002625) | 7.42234773 |
2 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 7.32605902 |
3 | Intrahepatic cholestasis (HP:0001406) | 7.27824808 |
4 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 6.61014173 |
5 | Prolonged partial thromboplastin time (HP:0003645) | 6.60692346 |
6 | Hypobetalipoproteinemia (HP:0003563) | 6.51283116 |
7 | Xanthomatosis (HP:0000991) | 6.33159559 |
8 | Hyperlipoproteinemia (HP:0010980) | 5.73136488 |
9 | Complement deficiency (HP:0004431) | 5.33841091 |
10 | Hypolipoproteinemia (HP:0010981) | 4.85767132 |
11 | Joint hemorrhage (HP:0005261) | 4.76299398 |
12 | Hyperammonemia (HP:0001987) | 4.60755824 |
13 | Epidermoid cyst (HP:0200040) | 4.51946949 |
14 | Abnormality of the common coagulation pathway (HP:0010990) | 4.50194108 |
15 | Hyperglycinemia (HP:0002154) | 4.47386430 |
16 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 4.44499964 |
17 | Ketosis (HP:0001946) | 4.29363472 |
18 | Hypoalphalipoproteinemia (HP:0003233) | 4.28877804 |
19 | Abnormality of methionine metabolism (HP:0010901) | 4.25126459 |
20 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.18166201 |
21 | Fat malabsorption (HP:0002630) | 4.12133813 |
22 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 4.08209412 |
23 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 3.98536648 |
24 | Hypoglycemic coma (HP:0001325) | 3.92770018 |
25 | Abnormality of glycine metabolism (HP:0010895) | 3.90857377 |
26 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.90857377 |
27 | Abnormality of complement system (HP:0005339) | 3.89356472 |
28 | Hyperglycinuria (HP:0003108) | 3.89033440 |
29 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.78628298 |
30 | Abnormality of the intrinsic pathway (HP:0010989) | 3.76966724 |
31 | Conjugated hyperbilirubinemia (HP:0002908) | 3.74877031 |
32 | Hypercholesterolemia (HP:0003124) | 3.62672732 |
33 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.44525591 |
34 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.40456696 |
35 | Hyperbilirubinemia (HP:0002904) | 3.34306710 |
36 | Osteomalacia (HP:0002749) | 3.29121791 |
37 | Spontaneous abortion (HP:0005268) | 3.15488879 |
38 | Delayed CNS myelination (HP:0002188) | 3.13820135 |
39 | Steatorrhea (HP:0002570) | 3.12738115 |
40 | Abnormality of serum amino acid levels (HP:0003112) | 3.05726278 |
41 | Abnormality of nucleobase metabolism (HP:0010932) | 3.04574682 |
42 | Ketoacidosis (HP:0001993) | 3.03663748 |
43 | Hypochromic microcytic anemia (HP:0004840) | 3.01453963 |
44 | Hepatocellular carcinoma (HP:0001402) | 2.94201058 |
45 | Myocardial infarction (HP:0001658) | 2.92363512 |
46 | Skin nodule (HP:0200036) | 2.77835223 |
47 | Metabolic acidosis (HP:0001942) | 2.76412335 |
48 | Systemic lupus erythematosus (HP:0002725) | 2.72304539 |
49 | Abnormality of purine metabolism (HP:0004352) | 2.67547874 |
50 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.61371936 |
51 | Dicarboxylic aciduria (HP:0003215) | 2.61371936 |
52 | Lethargy (HP:0001254) | 2.59563479 |
53 | Hypoglycemic seizures (HP:0002173) | 2.54425788 |
54 | Vascular calcification (HP:0004934) | 2.54049130 |
55 | Cholecystitis (HP:0001082) | 2.51025930 |
56 | Abnormal gallbladder physiology (HP:0012438) | 2.51025930 |
57 | Spastic diplegia (HP:0001264) | 2.47693508 |
58 | Abnormal gallbladder morphology (HP:0012437) | 2.47057052 |
59 | Acanthocytosis (HP:0001927) | 2.45645929 |
60 | Cholelithiasis (HP:0001081) | 2.43416436 |
61 | Gout (HP:0001997) | 2.39524566 |
62 | Glomerulonephritis (HP:0000099) | 2.38553912 |
63 | Cerebral edema (HP:0002181) | 2.36397878 |
64 | Mitral stenosis (HP:0001718) | 2.34748211 |
65 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.34300187 |
66 | Malnutrition (HP:0004395) | 2.33895591 |
67 | Glycosuria (HP:0003076) | 2.33135651 |
68 | Abnormality of urine glucose concentration (HP:0011016) | 2.33135651 |
69 | Reduced antithrombin III activity (HP:0001976) | 2.32496673 |
70 | Hyperphosphaturia (HP:0003109) | 2.32449771 |
71 | Irritability (HP:0000737) | 2.32125570 |
72 | Neonatal onset (HP:0003623) | 2.31258170 |
73 | Amyloidosis (HP:0011034) | 2.31151763 |
74 | Bifid scrotum (HP:0000048) | 2.27500775 |
75 | Cardiovascular calcification (HP:0011915) | 2.24817337 |
76 | Gingival bleeding (HP:0000225) | 2.23968595 |
77 | Arthropathy (HP:0003040) | 2.23857785 |
78 | Sensorimotor neuropathy (HP:0007141) | 2.19721686 |
79 | Brushfield spots (HP:0001088) | 2.18935191 |
80 | Late onset (HP:0003584) | 2.17817746 |
81 | Esophageal varix (HP:0002040) | 2.17302592 |
82 | Pancreatitis (HP:0001733) | 2.14819868 |
83 | Menorrhagia (HP:0000132) | 2.13172128 |
84 | Enlarged kidneys (HP:0000105) | 2.11489767 |
85 | Abnormal biliary tract physiology (HP:0012439) | 2.11097021 |
86 | Bile duct proliferation (HP:0001408) | 2.11097021 |
87 | Thrombophlebitis (HP:0004418) | 2.09613591 |
88 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.06457985 |
89 | Vomiting (HP:0002013) | 2.06012520 |
90 | Opisthotonus (HP:0002179) | 2.05892175 |
91 | Generalized aminoaciduria (HP:0002909) | 2.03960412 |
92 | Hemorrhage of the eye (HP:0011885) | 2.01329271 |
93 | Abnormality of the gallbladder (HP:0005264) | 2.00590953 |
94 | Poikilocytosis (HP:0004447) | 1.98415493 |
95 | Increased serum pyruvate (HP:0003542) | 1.94957535 |
96 | Rickets (HP:0002748) | 1.91419719 |
97 | Abnormality of iron homeostasis (HP:0011031) | 1.89167878 |
98 | Renal cortical cysts (HP:0000803) | 1.88642491 |
99 | Abnormal urine phosphate concentration (HP:0012599) | 1.87317924 |
100 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.86105185 |
101 | Purpura (HP:0000979) | 1.85865113 |
102 | Status epilepticus (HP:0002133) | 1.85699531 |
103 | Abnormal cartilage morphology (HP:0002763) | 1.84261123 |
104 | Hypophosphatemic rickets (HP:0004912) | 1.83675705 |
105 | Hydroxyprolinuria (HP:0003080) | 1.83280312 |
106 | Abnormality of proline metabolism (HP:0010907) | 1.83280312 |
107 | Elevated hepatic transaminases (HP:0002910) | 1.82201355 |
108 | Fair hair (HP:0002286) | 1.77704790 |
109 | Hyperglycemia (HP:0003074) | 1.77389286 |
110 | Pulmonary embolism (HP:0002204) | 1.75984107 |
111 | Abnormal enzyme/coenzyme activity (HP:0012379) | 1.74749541 |
112 | Abnormality of vitamin metabolism (HP:0100508) | 1.74722603 |
113 | Reticulocytosis (HP:0001923) | 1.73700197 |
114 | Abnormality of alanine metabolism (HP:0010916) | 1.72349936 |
115 | Hyperalaninemia (HP:0003348) | 1.72349936 |
116 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.72349936 |
117 | Nephritis (HP:0000123) | 1.70277491 |
118 | Acute encephalopathy (HP:0006846) | 1.65587150 |
119 | Birth length less than 3rd percentile (HP:0003561) | 1.64307622 |
120 | Neoplasm of the liver (HP:0002896) | 1.59548292 |
121 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.56179994 |
122 | Abnormality of glycolysis (HP:0004366) | 1.55187806 |
123 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.54306593 |
124 | Elevated alkaline phosphatase (HP:0003155) | 1.53261865 |
125 | Increased serum ferritin (HP:0003281) | 1.51318692 |
126 | Facial shape deformation (HP:0011334) | 1.50363980 |
127 | Potter facies (HP:0002009) | 1.50363980 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 7.17724402 |
2 | SIK1 | 4.67328965 |
3 | ERN1 | 4.62568078 |
4 | FGFR4 | 4.57182767 |
5 | STK16 | 3.73767984 |
6 | BRSK2 | 3.11594943 |
7 | TAOK3 | 3.10705906 |
8 | INSRR | 2.93631875 |
9 | ERBB4 | 2.90367977 |
10 | WNK4 | 2.67253202 |
11 | MAP2K4 | 2.50173198 |
12 | CDC7 | 2.44234843 |
13 | ZAK | 2.40424510 |
14 | TTK | 2.24653358 |
15 | PKN2 | 2.20480327 |
16 | EEF2K | 2.02965611 |
17 | MST1R | 2.02808202 |
18 | FLT3 | 1.91218829 |
19 | CDK12 | 1.90396447 |
20 | PIK3CG | 1.86477086 |
21 | MAPK11 | 1.81378748 |
22 | LATS1 | 1.80169168 |
23 | TRIB3 | 1.74654627 |
24 | DYRK2 | 1.69995684 |
25 | TYK2 | 1.61485920 |
26 | TAF1 | 1.57930522 |
27 | PNCK | 1.56216434 |
28 | DAPK2 | 1.53659497 |
29 | TLK1 | 1.53421943 |
30 | PLK4 | 1.49617704 |
31 | WNK3 | 1.49512248 |
32 | ABL2 | 1.47019953 |
33 | PTK6 | 1.41192962 |
34 | BRSK1 | 1.40309048 |
35 | NME1 | 1.39582261 |
36 | NEK9 | 1.38229434 |
37 | VRK2 | 1.37471193 |
38 | EIF2AK3 | 1.35593772 |
39 | CAMKK2 | 1.32127398 |
40 | KDR | 1.31166420 |
41 | FGFR2 | 1.30018880 |
42 | JAK2 | 1.21043998 |
43 | FRK | 1.19668226 |
44 | TNIK | 1.18707519 |
45 | MAP3K7 | 1.15987980 |
46 | MAP4K2 | 1.15081008 |
47 | PINK1 | 1.12650054 |
48 | MAP2K3 | 1.10653606 |
49 | PRKAA2 | 1.09331365 |
50 | GRK6 | 1.07802295 |
51 | MAPKAPK3 | 1.06709971 |
52 | PLK3 | 1.06482081 |
53 | TBK1 | 1.04384734 |
54 | PAK2 | 1.04277624 |
55 | MAPK4 | 1.03433186 |
56 | JAK1 | 1.00406918 |
57 | CDK7 | 1.00332561 |
58 | MAP3K10 | 0.97832784 |
59 | MAP3K14 | 0.97015353 |
60 | ERBB2 | 0.96989408 |
61 | SRPK1 | 0.96783061 |
62 | BCR | 0.95922268 |
63 | STK38L | 0.93941935 |
64 | NTRK3 | 0.93573183 |
65 | PRKCZ | 0.93424044 |
66 | ADRBK2 | 0.92854595 |
67 | CHEK2 | 0.91226722 |
68 | NEK2 | 0.91037273 |
69 | WEE1 | 0.90703152 |
70 | TSSK6 | 0.90524372 |
71 | CSNK1E | 0.87515244 |
72 | MAP3K3 | 0.87198539 |
73 | MAPK12 | 0.85955570 |
74 | CDK6 | 0.85732659 |
75 | EPHB1 | 0.84620945 |
76 | MET | 0.83544980 |
77 | PLK1 | 0.83416031 |
78 | MAP3K11 | 0.83155800 |
79 | CSNK2A1 | 0.82535649 |
80 | BMPR1B | 0.81459974 |
81 | MAP3K4 | 0.79830576 |
82 | MAPK15 | 0.78878492 |
83 | MUSK | 0.78626481 |
84 | TIE1 | 0.76142621 |
85 | ATR | 0.75552832 |
86 | FGFR1 | 0.75173769 |
87 | CSNK2A2 | 0.75158443 |
88 | PRKACG | 0.75082879 |
89 | RIPK1 | 0.73809081 |
90 | DYRK1B | 0.73080685 |
91 | EPHA3 | 0.73072564 |
92 | EIF2AK1 | 0.72958034 |
93 | MAPKAPK5 | 0.71159098 |
94 | NEK1 | 0.70392677 |
95 | CSK | 0.70369598 |
96 | NUAK1 | 0.70042775 |
97 | CAMK2G | 0.69186198 |
98 | CSNK1D | 0.68730077 |
99 | CDK8 | 0.68310956 |
100 | GSK3A | 0.66997739 |
101 | VRK1 | 0.66905053 |
102 | IRAK3 | 0.66073799 |
103 | SGK3 | 0.64884035 |
104 | MAP2K6 | 0.63616749 |
105 | FGFR3 | 0.63387457 |
106 | TYRO3 | 0.63225503 |
107 | PRKAA1 | 0.63001820 |
108 | CAMK1D | 0.62761229 |
109 | EPHA4 | 0.61778919 |
110 | ATM | 0.61394835 |
111 | KSR2 | 0.60765588 |
112 | MAPK7 | 0.60438837 |
113 | PRKACA | 0.60378492 |
114 | TGFBR2 | 0.58544271 |
115 | MAP2K7 | 0.56962622 |
116 | AKT2 | 0.56892138 |
117 | WNK1 | 0.55633349 |
118 | PTK2 | 0.53792183 |
119 | MAP3K6 | 0.52464877 |
120 | CSF1R | 0.52112415 |
121 | MAP3K5 | 0.51272555 |
122 | NLK | 0.50468353 |
123 | PRKG1 | 0.50317857 |
124 | PRKCQ | 0.50278895 |
125 | IKBKE | 0.50158445 |
126 | SGK2 | 0.49701738 |
127 | CDK1 | 0.49141147 |
128 | PDPK1 | 0.47334821 |
129 | BUB1 | 0.46683556 |
130 | TAOK2 | 0.46594640 |
131 | IGF1R | 0.44733082 |
132 | CSNK1G1 | 0.43299208 |
133 | RET | 0.43267807 |
134 | CSNK1A1 | 0.43160170 |
135 | ACVR1B | 0.42813949 |
136 | CDK4 | 0.42717851 |
137 | MAP3K13 | 0.42668921 |
138 | PRKDC | 0.42543350 |
139 | LATS2 | 0.41573637 |
140 | PRKCG | 0.40682792 |
141 | MAP2K1 | 0.40675123 |
142 | PRKACB | 0.40104847 |
143 | RPS6KA5 | 0.40046188 |
144 | GRK1 | 0.39275584 |
145 | ICK | 0.38880244 |
146 | RPS6KB2 | 0.38690082 |
147 | PKN1 | 0.38375206 |
148 | RPS6KA3 | 0.38155325 |
149 | PRKCI | 0.37662617 |
150 | CAMK4 | 0.34762857 |
151 | MTOR | 0.33533821 |
152 | SGK494 | 0.33170801 |
153 | SGK223 | 0.33170801 |
154 | EGFR | 0.32533995 |
155 | PDK1 | 0.29458419 |
156 | IRAK2 | 0.29010881 |
157 | IRAK1 | 0.28477338 |
158 | MAP3K1 | 0.27153762 |
159 | AKT3 | 0.26742181 |
160 | PRKCA | 0.25953050 |
161 | PBK | 0.25546397 |
162 | CSNK1G2 | 0.23688034 |
163 | PDK3 | 0.22179792 |
164 | PDK4 | 0.22179792 |
165 | PIK3CA | 0.21791184 |
166 | ABL1 | 0.21713162 |
167 | CAMK1G | 0.21178319 |
168 | BMX | 0.21127256 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 4.56519403 |
2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.50830468 |
3 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.36790648 |
4 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.30815884 |
5 | Arginine biosynthesis_Homo sapiens_hsa00220 | 3.01599825 |
6 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.82769795 |
7 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.76425742 |
8 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.69122808 |
9 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.63447967 |
10 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.57016618 |
11 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.51062341 |
12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.42559244 |
13 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.25835179 |
14 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.20567551 |
15 | Peroxisome_Homo sapiens_hsa04146 | 2.10829779 |
16 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.10432760 |
17 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.93663021 |
18 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.93402984 |
19 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.92329811 |
20 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.92244834 |
21 | Histidine metabolism_Homo sapiens_hsa00340 | 1.90367344 |
22 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.90321690 |
23 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.88219268 |
24 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.76612599 |
25 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.75213253 |
26 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.74858171 |
27 | Retinol metabolism_Homo sapiens_hsa00830 | 1.72762292 |
28 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.71846018 |
29 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.71639637 |
30 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.69969089 |
31 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.69121127 |
32 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.53777860 |
33 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.51838214 |
34 | Bile secretion_Homo sapiens_hsa04976 | 1.50684749 |
35 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.49482768 |
36 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.46072587 |
37 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.43183243 |
38 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.40254350 |
39 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.38095016 |
40 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.30068371 |
41 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.29566890 |
42 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.27122786 |
43 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.20822967 |
44 | ABC transporters_Homo sapiens_hsa02010 | 1.20134584 |
45 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.17653012 |
46 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.17246944 |
47 | Carbon metabolism_Homo sapiens_hsa01200 | 1.11896820 |
48 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.09886968 |
49 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.02615518 |
50 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.99169787 |
51 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.97681476 |
52 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.97091685 |
53 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.96943308 |
54 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.96693151 |
55 | Sulfur relay system_Homo sapiens_hsa04122 | 0.95627964 |
56 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.85921039 |
57 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.84868897 |
58 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.83803116 |
59 | Lysine degradation_Homo sapiens_hsa00310 | 0.83203215 |
60 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.74681693 |
61 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.70592301 |
62 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.69227996 |
63 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.60332715 |
64 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.56212151 |
65 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.55538339 |
66 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.50472829 |
67 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45520330 |
68 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.45242977 |
69 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.43956900 |
70 | Prion diseases_Homo sapiens_hsa05020 | 0.36658445 |
71 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.27953608 |
72 | Galactose metabolism_Homo sapiens_hsa00052 | 0.24221369 |
73 | Insulin resistance_Homo sapiens_hsa04931 | 0.24120648 |
74 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.23585034 |
75 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.23365064 |
76 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.23126758 |
77 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.17443945 |
78 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.16072017 |
79 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.15366530 |
80 | RNA polymerase_Homo sapiens_hsa03020 | 0.14929410 |
81 | Protein export_Homo sapiens_hsa03060 | 0.13180128 |
82 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.11811805 |
83 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.11762218 |
84 | Ribosome_Homo sapiens_hsa03010 | 0.08985111 |
85 | DNA replication_Homo sapiens_hsa03030 | 0.08010272 |
86 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.07525056 |
87 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.06129628 |
88 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.05384492 |
89 | Homologous recombination_Homo sapiens_hsa03440 | 0.04950943 |
90 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.02439996 |
91 | Circadian rhythm_Homo sapiens_hsa04710 | 0.01529292 |
92 | Bladder cancer_Homo sapiens_hsa05219 | -0.2455432 |
93 | Amoebiasis_Homo sapiens_hsa05146 | -0.2406783 |
94 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | -0.2383736 |
95 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | -0.2357363 |
96 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.2289752 |
97 | Renin-angiotensin system_Homo sapiens_hsa04614 | -0.2068861 |
98 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | -0.1986308 |
99 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | -0.1922643 |
100 | Hepatitis C_Homo sapiens_hsa05160 | -0.1744608 |
101 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | -0.1647799 |
102 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | -0.1631430 |
103 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.1617081 |
104 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | -0.1495507 |
105 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | -0.1482204 |
106 | Regulation of autophagy_Homo sapiens_hsa04140 | -0.1462761 |
107 | African trypanosomiasis_Homo sapiens_hsa05143 | -0.1310485 |
108 | Insulin signaling pathway_Homo sapiens_hsa04910 | -0.1015619 |
109 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | -0.0891671 |
110 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.0710182 |
111 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | -0.0591481 |
112 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | -0.0331094 |
113 | Parkinsons disease_Homo sapiens_hsa05012 | -0.0316232 |
114 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | -0.0221813 |
115 | Pertussis_Homo sapiens_hsa05133 | -0.0163566 |
116 | Mismatch repair_Homo sapiens_hsa03430 | -0.0151798 |