INPP5A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of potassium ion transmembrane transporter activity (GO:1901017)5.65558277
2sarcomere organization (GO:0045214)5.55025948
3cardiac myofibril assembly (GO:0055003)5.51611112
4regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO5.48218198
5negative regulation of potassium ion transmembrane transport (GO:1901380)5.43602554
6positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.35926809
7cell communication by electrical coupling involved in cardiac conduction (GO:0086064)5.28586098
8regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)5.05689076
9regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)4.98654469
10regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.98247683
11plasma membrane repair (GO:0001778)4.91565020
12cardiac muscle contraction (GO:0060048)4.86199391
13myofibril assembly (GO:0030239)4.84866679
14regulation of actin filament-based movement (GO:1903115)4.71383404
15cell communication by electrical coupling (GO:0010644)4.58156519
16cell communication involved in cardiac conduction (GO:0086065)4.48999925
17regulation of cell communication by electrical coupling (GO:0010649)4.42809785
18tricarboxylic acid cycle (GO:0006099)4.30345507
19ventricular cardiac muscle cell action potential (GO:0086005)4.28991280
20regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.21938531
21regulation of membrane repolarization (GO:0060306)4.13573304
22sarcoplasmic reticulum calcium ion transport (GO:0070296)4.11372707
23muscle filament sliding (GO:0030049)4.10094811
24actin-myosin filament sliding (GO:0033275)4.10094811
25relaxation of cardiac muscle (GO:0055119)4.08870574
26regulation of cardiac muscle cell contraction (GO:0086004)3.88028129
27actomyosin structure organization (GO:0031032)3.84936132
28membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.81940553
29potassium ion import (GO:0010107)3.81932919
30cardiac muscle cell development (GO:0055013)3.80852669
31sodium ion export (GO:0071436)3.78055024
32regulation of striated muscle contraction (GO:0006942)3.74042258
33regulation of relaxation of muscle (GO:1901077)3.72467300
34regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.71725146
35striated muscle contraction (GO:0006941)3.71046093
36positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.65728016
37synaptic vesicle docking involved in exocytosis (GO:0016081)3.65301445
38cerebellar granule cell differentiation (GO:0021707)3.62795462
39bundle of His cell to Purkinje myocyte communication (GO:0086069)3.62007914
40cardiac muscle hypertrophy (GO:0003300)3.60903119
41regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.60774091
42carnitine shuttle (GO:0006853)3.60672903
43heart trabecula formation (GO:0060347)3.60094646
44regulation of the force of heart contraction (GO:0002026)3.57292792
45negative regulation of protein localization to cell surface (GO:2000009)3.54902656
46cardiac cell development (GO:0055006)3.54416964
47adult heart development (GO:0007512)3.53058101
48regulation of skeletal muscle contraction (GO:0014819)3.52298706
49actin-mediated cell contraction (GO:0070252)3.47147483
50regulation of cardiac muscle contraction (GO:0055117)3.43856143
51striated muscle hypertrophy (GO:0014897)3.43543990
52cardiac conduction (GO:0061337)3.39926200
53regulation of calcium ion transmembrane transporter activity (GO:1901019)3.39820291
54regulation of calcium ion transmembrane transport (GO:1903169)3.39820291
55positive regulation of potassium ion transmembrane transport (GO:1901381)3.39673830
56positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.34449351
57cardiac muscle tissue morphogenesis (GO:0055008)3.33111377
58cardiac muscle cell action potential involved in contraction (GO:0086002)3.31399936
59cellular potassium ion homeostasis (GO:0030007)3.30036206
60regulation of acyl-CoA biosynthetic process (GO:0050812)3.27816530
61ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.26104051
62creatine metabolic process (GO:0006600)3.26091300
63regulation of heart rate by cardiac conduction (GO:0086091)3.26059010
64cardiac muscle cell action potential (GO:0086001)3.25481525
65membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.23656667
66regulation of sarcomere organization (GO:0060297)3.20558833
67fatty acid transmembrane transport (GO:1902001)3.15995609
68cell-substrate adherens junction assembly (GO:0007045)3.14736089
69focal adhesion assembly (GO:0048041)3.14736089
70detection of calcium ion (GO:0005513)3.14184188
71glutamate secretion (GO:0014047)3.10965982
72adherens junction assembly (GO:0034333)3.08204654
73regulation of heart rate (GO:0002027)3.07866209
74negative regulation of potassium ion transport (GO:0043267)3.04858071
75positive regulation of cation channel activity (GO:2001259)3.03525671
76muscle tissue morphogenesis (GO:0060415)3.00794286
77membrane repolarization (GO:0086009)2.99435722
78regulation of coenzyme metabolic process (GO:0051196)2.98110096
79regulation of cofactor metabolic process (GO:0051193)2.98110096
80membrane repolarization during action potential (GO:0086011)2.96829679
81cytoskeletal anchoring at plasma membrane (GO:0007016)2.96755095
82response to pheromone (GO:0019236)2.96067914
83activation of protein kinase A activity (GO:0034199)2.96022649
84regulation of heart contraction (GO:0008016)2.95102287
85carnitine transmembrane transport (GO:1902603)2.94081985
86muscle hypertrophy (GO:0014896)2.93096206
87negative regulation of cytosolic calcium ion concentration (GO:0051481)2.92072924
88positive regulation of potassium ion transport (GO:0043268)2.91491513
89NADH metabolic process (GO:0006734)2.91145309
90regulation of potassium ion transmembrane transport (GO:1901379)2.90203075
91relaxation of muscle (GO:0090075)2.88260832
92muscle contraction (GO:0006936)2.87952537
93regulation of potassium ion transmembrane transporter activity (GO:1901016)2.87042224
94skeletal muscle contraction (GO:0003009)2.87035267
95synaptic vesicle exocytosis (GO:0016079)2.86830565
96negative regulation of homotypic cell-cell adhesion (GO:0034111)2.84942597
97cellular sodium ion homeostasis (GO:0006883)2.83377527
98regulation of synaptic vesicle exocytosis (GO:2000300)2.82295006
99negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.81697431
100actin filament-based movement (GO:0030048)2.80390061
101growth hormone secretion (GO:0030252)2.80077924
102synaptic vesicle maturation (GO:0016188)2.79562528
103cardiac muscle adaptation (GO:0014887)2.78025556
104cardiac muscle hypertrophy in response to stress (GO:0014898)2.78025556
105muscle hypertrophy in response to stress (GO:0003299)2.78025556
106relaxation of smooth muscle (GO:0044557)2.76468104
107cellular response to epinephrine stimulus (GO:0071872)2.75782924
108amino-acid betaine transport (GO:0015838)2.73000545
109carnitine transport (GO:0015879)2.73000545
110regulation of short-term neuronal synaptic plasticity (GO:0048172)2.72569038
111positive regulation of sodium ion transport (GO:0010765)2.72107920
112negative regulation of calcium ion transmembrane transporter activity (GO:1901020)2.71225889
113negative regulation of calcium ion transmembrane transport (GO:1903170)2.71225889
114response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.71165828
115regulation of cation channel activity (GO:2001257)2.70532114
116positive regulation of ion transmembrane transporter activity (GO:0032414)2.70153823
117positive regulation of heart contraction (GO:0045823)2.69061873
118muscle system process (GO:0003012)2.66707174
119neuronal action potential propagation (GO:0019227)2.65269854
120regulation of cardioblast differentiation (GO:0051890)2.65059354
121negative regulation of fatty acid transport (GO:2000192)2.63376914
122positive regulation of synapse maturation (GO:0090129)2.61791554
123neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.61041945
124cellular response to monoamine stimulus (GO:0071868)2.57231135
125cellular response to catecholamine stimulus (GO:0071870)2.57231135
126layer formation in cerebral cortex (GO:0021819)2.56538842
127response to muscle activity (GO:0014850)2.56298199
128skeletal muscle fiber development (GO:0048741)2.53923543
129regulation of early endosome to late endosome transport (GO:2000641)2.53318960
130regulation of synaptic vesicle transport (GO:1902803)2.53118087
131cGMP-mediated signaling (GO:0019934)2.52822491
132protein targeting to plasma membrane (GO:0072661)2.47793846
133cell-substrate junction assembly (GO:0007044)2.45770896
134peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.44585304
135positive regulation of receptor recycling (GO:0001921)2.43124328
136response to epinephrine (GO:0071871)2.42719990
137stress fiber assembly (GO:0043149)2.41577792
138striated muscle adaptation (GO:0014888)2.37192020
139fructose metabolic process (GO:0006000)2.35429591
140positive regulation of muscle hypertrophy (GO:0014742)2.34328544
141positive regulation of cardiac muscle hypertrophy (GO:0010613)2.34328544

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.60467769
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.95728075
3* EP300_21415370_ChIP-Seq_HL-1_Mouse2.67991671
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.47801139
5DROSHA_22980978_ChIP-Seq_HELA_Human2.35399859
6ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.32958730
7NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.27325786
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.14675571
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.14675571
10* TBX20_22080862_ChIP-Seq_HEART_Mouse2.08581231
11* TBX20_22328084_ChIP-Seq_HEART_Mouse2.08581231
12MTF2_20144788_ChIP-Seq_MESCs_Mouse2.01703704
13SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.99996851
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.99050263
15RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.94304847
16ESR1_20079471_ChIP-ChIP_T-47D_Human1.91721378
17THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.83896826
18CDX2_19796622_ChIP-Seq_MESCs_Mouse1.83534872
19EZH2_27294783_Chip-Seq_ESCs_Mouse1.82659113
20MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.82194785
21SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.76715455
22* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.70710862
23JARID2_20075857_ChIP-Seq_MESCs_Mouse1.64221078
24EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.63183934
25ZNF263_19887448_ChIP-Seq_K562_Human1.62110226
26EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.59244988
27SMAD_19615063_ChIP-ChIP_OVARY_Human1.58362663
28SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.57926101
29TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.57386424
30SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.54519875
31* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.53580934
32EZH2_27304074_Chip-Seq_ESCs_Mouse1.52675123
33PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.51856754
34SUZ12_27294783_Chip-Seq_ESCs_Mouse1.50550135
35* RARB_27405468_Chip-Seq_BRAIN_Mouse1.50323072
36ESR2_21235772_ChIP-Seq_MCF-7_Human1.48685538
37EED_16625203_ChIP-ChIP_MESCs_Mouse1.47382076
38RNF2_27304074_Chip-Seq_ESCs_Mouse1.46331200
39ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.44542273
40RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.44288785
41RARG_19884340_ChIP-ChIP_MEFs_Mouse1.43758642
42KDM2B_26808549_Chip-Seq_K562_Human1.38735639
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.37493952
44CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.31791861
45ZNF274_21170338_ChIP-Seq_K562_Hela1.31783738
46TRIM28_21343339_ChIP-Seq_HEK293_Human1.29138309
47NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.26219601
48PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.26069709
49WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.24062535
50WT1_25993318_ChIP-Seq_PODOCYTE_Human1.23790994
51* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.23052419
52ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.22671026
53* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.22384513
54ELK3_25401928_ChIP-Seq_HUVEC_Human1.19820748
55REST_21632747_ChIP-Seq_MESCs_Mouse1.19182977
56ESR1_21235772_ChIP-Seq_MCF-7_Human1.18845800
57EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.17681902
58DNAJC2_21179169_ChIP-ChIP_NT2_Human1.17026278
59WT1_19549856_ChIP-ChIP_CCG9911_Human1.16793140
60NR3C1_23031785_ChIP-Seq_PC12_Mouse1.16776959
61MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.16748509
62RACK7_27058665_Chip-Seq_MCF-7_Human1.16293920
63* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.16194037
64CLOCK_20551151_ChIP-Seq_293T_Human1.14647045
65* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.14074233
66P300_27058665_Chip-Seq_ZR-75-30cells_Human1.12846706
67REST_18959480_ChIP-ChIP_MESCs_Mouse1.12781918
68TCF7_22412390_ChIP-Seq_EML_Mouse1.11588331
69SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.10377818
70ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.09301608
71ZFP281_18757296_ChIP-ChIP_E14_Mouse1.08859840
72SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.08720981
73CTNNB1_20460455_ChIP-Seq_HCT116_Human1.08583259
74NFIB_24661679_ChIP-Seq_LUNG_Mouse1.06519574
75ERG_21242973_ChIP-ChIP_JURKAT_Human1.06512938
76IKZF1_21737484_ChIP-ChIP_HCT116_Human1.06296160
77GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05625414
78GBX2_23144817_ChIP-Seq_PC3_Human1.05455094
79* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.00910702
80FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.00703000
81* AR_19668381_ChIP-Seq_PC3_Human0.99577389
82SOX2_21211035_ChIP-Seq_LN229_Gbm0.99466314
83GATA1_19941826_ChIP-Seq_K562_Human0.99406030
84TP53_23651856_ChIP-Seq_MEFs_Mouse0.99258232
85* FOXA2_19822575_ChIP-Seq_HepG2_Human0.99239603
86CTCF_27219007_Chip-Seq_Bcells_Human0.99126505
87LXR_22292898_ChIP-Seq_THP-1_Human0.98728344
88RING1B_27294783_Chip-Seq_ESCs_Mouse0.98235175
89* KDM2B_26808549_Chip-Seq_DND41_Human0.97348270
90* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97306767
91* CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.97151835
92* KDM2B_26808549_Chip-Seq_JURKAT_Human0.97022026
93SMAD3_21741376_ChIP-Seq_HESCs_Human0.96676660
94* ZNF217_24962896_ChIP-Seq_MCF-7_Human0.96152919
95* SMAD4_21741376_ChIP-Seq_HESCs_Human0.95982662
96ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.95770261
97SMAD4_21799915_ChIP-Seq_A2780_Human0.95044542
98ISL1_27105846_Chip-Seq_CPCs_Mouse0.94736420
99RING1B_27294783_Chip-Seq_NPCs_Mouse0.94706273
100NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.94547641
101TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94273177
102NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.93823869
103UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.93703846
104PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.92882144
105SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92669222
106ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.91398219
107TP53_16413492_ChIP-PET_HCT116_Human0.90839512
108TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90011833
109SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.89561939
110SMC1_22415368_ChIP-Seq_MEFs_Mouse0.89337059
111KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.89332297
112CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.89224699
113AHR_22903824_ChIP-Seq_MCF-7_Human0.89088314
114SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.88219382
115DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.87397759
116TET1_21490601_ChIP-Seq_MESCs_Mouse0.87193149
117GATA2_21666600_ChIP-Seq_HMVEC_Human0.86868288
118BCAT_22108803_ChIP-Seq_LS180_Human0.85578373
119LXR_22158963_ChIP-Seq_LIVER_Mouse0.85548056
120* TP63_22573176_ChIP-Seq_HFKS_Human0.84716307
121PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.84079372
122AR_21572438_ChIP-Seq_LNCaP_Human0.83837393
123PPAR_26484153_Chip-Seq_NCI-H1993_Human0.83518528
124* KLF4_19829295_ChIP-Seq_ESCs_Human0.82019129
125TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.81236776
126ARNT_22903824_ChIP-Seq_MCF-7_Human0.81123324
127PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.80820890
128* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.77473367
129MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.76025263
130NRF2_20460467_ChIP-Seq_MEFs_Mouse0.75759861

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis5.43400433
2MP0004084_abnormal_cardiac_muscle4.70031462
3MP0000751_myopathy4.42477787
4MP0003646_muscle_fatigue4.35974313
5MP0004215_abnormal_myocardial_fiber4.09582236
6MP0004036_abnormal_muscle_relaxation3.74125691
7MP0004145_abnormal_muscle_electrophysio3.34020485
8MP0005330_cardiomyopathy2.98159658
9MP0000749_muscle_degeneration2.97848558
10MP0003137_abnormal_impulse_conducting2.63110592
11MP0004087_abnormal_muscle_fiber2.60954858
12MP0002972_abnormal_cardiac_muscle2.55588596
13MP0008775_abnormal_heart_ventricle2.48410094
14MP0004484_altered_response_of2.42185888
15MP0005620_abnormal_muscle_contractility2.31863395
16MP0006138_congestive_heart_failure2.27294462
17MP0004130_abnormal_muscle_cell2.26802032
18MP0002106_abnormal_muscle_physiology2.09070698
19MP0001544_abnormal_cardiovascular_syste2.07779894
20MP0005385_cardiovascular_system_phenoty2.07779894
21MP0004085_abnormal_heartbeat2.05626465
22MP0000747_muscle_weakness1.99776568
23MP0010630_abnormal_cardiac_muscle1.97755265
24MP0000750_abnormal_muscle_regeneration1.92569063
25MP0009046_muscle_twitch1.91973214
26MP0004859_abnormal_synaptic_plasticity1.90441526
27MP0003880_abnormal_central_pattern1.90269687
28MP0002269_muscular_atrophy1.89966038
29MP0004233_abnormal_muscle_weight1.80160027
30MP0005369_muscle_phenotype1.75611352
31MP0000759_abnormal_skeletal_muscle1.72764166
32MP0008569_lethality_at_weaning1.67622079
33MP0005409_darkened_coat_color1.64109356
34MP0005423_abnormal_somatic_nervous1.60358213
35MP0005451_abnormal_body_composition1.60238637
36MP0004043_abnormal_pH_regulation1.57883352
37MP0005623_abnormal_meninges_morphology1.56978653
38MP0004510_myositis1.52774743
39MP0000013_abnormal_adipose_tissue1.49654835
40MP0003828_pulmonary_edema1.45933065
41MP0003879_abnormal_hair_cell1.45643143
42MP0003635_abnormal_synaptic_transmissio1.43224302
43MP0002909_abnormal_adrenal_gland1.36573569
44MP0005666_abnormal_adipose_tissue1.31196178
45MP0000733_abnormal_muscle_development1.23196115
46MP0003950_abnormal_plasma_membrane1.20626648
47MP0002272_abnormal_nervous_system1.19767792
48MP0003221_abnormal_cardiomyocyte_apopto1.16526448
49MP0002332_abnormal_exercise_endurance1.15426964
50MP0003091_abnormal_cell_migration1.13954348
51MP0003279_aneurysm1.13541856
52MP0004270_analgesia1.13513967
53MP0003705_abnormal_hypodermis_morpholog1.11543492
54MP0006036_abnormal_mitochondrial_physio1.10858004
55MP0003329_amyloid_beta_deposits1.09409167
56MP0008004_abnormal_stomach_pH1.09285037
57MP0005375_adipose_tissue_phenotype1.08253008
58MP0000767_abnormal_smooth_muscle1.07875245
59MP0002127_abnormal_cardiovascular_syste1.07469038
60MP0005670_abnormal_white_adipose1.07386464
61MP0004147_increased_porphyrin_level1.06782720
62MP0009780_abnormal_chondrocyte_physiolo1.05810876
63MP0005167_abnormal_blood-brain_barrier1.04288575
64MP0008874_decreased_physiological_sensi1.04187454
65MP0002064_seizures1.02389648
66MP0000003_abnormal_adipose_tissue1.02357141
67MP0009745_abnormal_behavioral_response1.00433912
68MP0001440_abnormal_grooming_behavior0.99844522
69MP0010368_abnormal_lymphatic_system0.98820697
70MP0004185_abnormal_adipocyte_glucose0.98413655
71MP0005595_abnormal_vascular_smooth0.97800821
72MP0002234_abnormal_pharynx_morphology0.97263731
73MP0005165_increased_susceptibility_to0.95201997
74MP0005503_abnormal_tendon_morphology0.92621648
75MP0002108_abnormal_muscle_morphology0.90143196
76MP0004924_abnormal_behavior0.88065569
77MP0005386_behavior/neurological_phenoty0.88065569
78MP0002067_abnormal_sensory_capabilities0.87726126
79MP0001849_ear_inflammation0.87110282
80MP0000266_abnormal_heart_morphology0.86891713
81MP0004272_abnormal_basement_membrane0.85780600
82MP0000534_abnormal_ureter_morphology0.84541015
83MP0000230_abnormal_systemic_arterial0.83512935
84MP0005187_abnormal_penis_morphology0.82852962
85MP0002063_abnormal_learning/memory/cond0.82055068
86MP0008961_abnormal_basal_metabolism0.79798131
87MP0003045_fibrosis0.79515267
88MP0008438_abnormal_cutaneous_collagen0.79033614
89MP0000537_abnormal_urethra_morphology0.77590163
90MP0006035_abnormal_mitochondrial_morpho0.77539116
91MP0009384_cardiac_valve_regurgitation0.74847885
92MP0002971_abnormal_brown_adipose0.71971670
93MP0002734_abnormal_mechanical_nocicepti0.70778455
94MP0002896_abnormal_bone_mineralization0.70243871
95MP0003634_abnormal_glial_cell0.69879745
96MP0002089_abnormal_postnatal_growth/wei0.69610579
97MP0003123_paternal_imprinting0.69493327
98MP0004885_abnormal_endolymph0.69419297
99MP0000920_abnormal_myelination0.69131498
100MP0000343_altered_response_to0.68982488
101MP0002735_abnormal_chemical_nociception0.68955959
102MP0008260_abnormal_autophagy0.68414948
103MP0002572_abnormal_emotion/affect_behav0.67895073
104MP0003633_abnormal_nervous_system0.67599273
105MP0003690_abnormal_glial_cell0.64434587
106MP0001486_abnormal_startle_reflex0.63240424
107MP0005275_abnormal_skin_tensile0.62996370
108MP0003283_abnormal_digestive_organ0.62368567
109MP0005083_abnormal_biliary_tract0.62302019
110MP0002066_abnormal_motor_capabilities/c0.61986326
111MP0004142_abnormal_muscle_tone0.61752812
112MP0001299_abnormal_eye_distance/0.60915527
113MP0003566_abnormal_cell_adhesion0.60846439
114MP0002128_abnormal_blood_circulation0.60083249
115MP0001958_emphysema0.59222044
116MP0002822_catalepsy0.58565101
117MP0005535_abnormal_body_temperature0.58202667
118MP0004858_abnormal_nervous_system0.57275917
119MP0001879_abnormal_lymphatic_vessel0.57233261
120MP0002184_abnormal_innervation0.56549464
121MP0003567_abnormal_fetal_cardiomyocyte0.56086126

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)6.73360529
2Exercise-induced myalgia (HP:0003738)5.39446241
3Ventricular tachycardia (HP:0004756)5.34842849
4Nemaline bodies (HP:0003798)5.16504873
5Exercise-induced muscle cramps (HP:0003710)5.07887656
6Atrial fibrillation (HP:0005110)5.07698733
7Calf muscle hypertrophy (HP:0008981)4.97728202
8Bundle branch block (HP:0011710)4.92170974
9Muscle fiber splitting (HP:0003555)4.85611895
10Primary atrial arrhythmia (HP:0001692)4.73853376
11Muscle hypertrophy of the lower extremities (HP:0008968)4.71852474
12Hyporeflexia of lower limbs (HP:0002600)4.52588028
13Supraventricular tachycardia (HP:0004755)4.52121345
14Syncope (HP:0001279)4.51843797
15Supraventricular arrhythmia (HP:0005115)4.46613919
16Right ventricular cardiomyopathy (HP:0011663)4.29787273
17Ventricular fibrillation (HP:0001663)4.29641820
18Abnormality of the calf musculature (HP:0001430)4.29217946
19Myoglobinuria (HP:0002913)4.11865430
20Prolonged QT interval (HP:0001657)4.11266142
21Lipoatrophy (HP:0100578)3.91408531
22Subaortic stenosis (HP:0001682)3.86445780
23Abnormality of the left ventricular outflow tract (HP:0011103)3.86445780
24Heart block (HP:0012722)3.71978379
25Ventricular arrhythmia (HP:0004308)3.71638055
26Myotonia (HP:0002486)3.65041728
27Difficulty running (HP:0009046)3.59630683
28Dysmetric saccades (HP:0000641)3.54049331
29Abnormal atrioventricular conduction (HP:0005150)3.50604197
30EMG: myopathic abnormalities (HP:0003458)3.46735902
31Dilated cardiomyopathy (HP:0001644)3.32138582
32Atrioventricular block (HP:0001678)3.31139908
33Asymmetric septal hypertrophy (HP:0001670)3.29701027
34Palpitations (HP:0001962)3.27353851
35Atonic seizures (HP:0010819)3.21086084
36Centrally nucleated skeletal muscle fibers (HP:0003687)3.19835293
37Increased connective tissue (HP:0009025)3.18240085
38Abnormal EKG (HP:0003115)3.00310287
39Aortic aneurysm (HP:0004942)2.98352370
40Round ear (HP:0100830)2.96607431
41Broad metatarsal (HP:0001783)2.90666066
42Distal arthrogryposis (HP:0005684)2.90491732
43Increased variability in muscle fiber diameter (HP:0003557)2.87150290
44Action tremor (HP:0002345)2.85606972
45Protrusio acetabuli (HP:0003179)2.77771544
46Febrile seizures (HP:0002373)2.71377048
47Myopathic facies (HP:0002058)2.69243268
48Muscle stiffness (HP:0003552)2.64855551
49Spinal rigidity (HP:0003306)2.63380421
50Ketoacidosis (HP:0001993)2.63095415
51Rhabdomyolysis (HP:0003201)2.60230370
52Difficulty climbing stairs (HP:0003551)2.56925475
53Cerebral aneurysm (HP:0004944)2.55635164
54Premature rupture of membranes (HP:0001788)2.49596634
55Abnormality of skeletal muscle fiber size (HP:0012084)2.47807668
56Type 1 muscle fiber predominance (HP:0003803)2.38954716
57Dysdiadochokinesis (HP:0002075)2.38294624
58Vascular tortuosity (HP:0004948)2.35202751
59Visual hallucinations (HP:0002367)2.33311707
60Left ventricular hypertrophy (HP:0001712)2.33126035
61Pheochromocytoma (HP:0002666)2.31973598
62Arterial tortuosity (HP:0005116)2.28863405
63Ankle clonus (HP:0011448)2.25914698
64Obstructive sleep apnea (HP:0002870)2.18183210
65Frequent falls (HP:0002359)2.17768835
66Hemiplegia (HP:0002301)2.16490178
67Rimmed vacuoles (HP:0003805)2.14844720
68Progressive cerebellar ataxia (HP:0002073)2.13912817
69Ulnar deviation of the wrist (HP:0003049)2.11709771
70Neck muscle weakness (HP:0000467)2.11418102
71Slender build (HP:0001533)2.09611311
72Limb-girdle muscle atrophy (HP:0003797)1.97700666
73Aortic dissection (HP:0002647)1.97664894
74Hypoglycemic coma (HP:0001325)1.96443142
75Sudden cardiac death (HP:0001645)1.96329212
76EMG: neuropathic changes (HP:0003445)1.94787241
77Palmoplantar keratoderma (HP:0000982)1.94136480
78Gaze-evoked nystagmus (HP:0000640)1.94028295
79Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.93789524
80Muscle fiber inclusion bodies (HP:0100299)1.93776206
81Hypoplastic ischia (HP:0003175)1.93232829
82Neuroendocrine neoplasm (HP:0100634)1.92386221
83Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.91966941
84Mildly elevated creatine phosphokinase (HP:0008180)1.91935891
85Scapular winging (HP:0003691)1.90256294
86Focal motor seizures (HP:0011153)1.88985336
87Slow progression (HP:0003677)1.88763820
88Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.88150619
89Supranuclear gaze palsy (HP:0000605)1.87204528
90Hamartoma of the eye (HP:0010568)1.87158578
91Abnormality of the foot musculature (HP:0001436)1.86905152
92Rapidly progressive (HP:0003678)1.86040666
93Bulbar palsy (HP:0001283)1.85093539
94Aneurysm (HP:0002617)1.84980856
95Dysmetria (HP:0001310)1.84677588
96Conjunctival hamartoma (HP:0100780)1.84635276
97Foot dorsiflexor weakness (HP:0009027)1.83647002
98Calcaneovalgus deformity (HP:0001848)1.83297842
99Ketosis (HP:0001946)1.83228900
100Abnormal mitochondria in muscle tissue (HP:0008316)1.82925049
101Gowers sign (HP:0003391)1.82524939
102Truncal ataxia (HP:0002078)1.81353254
103Absence seizures (HP:0002121)1.80705649
104Scanning speech (HP:0002168)1.80584985
105Resting tremor (HP:0002322)1.79894157
106Athetosis (HP:0002305)1.78827810
107Large for gestational age (HP:0001520)1.73813113
108Facial diplegia (HP:0001349)1.73603394
109Distal lower limb amyotrophy (HP:0008944)1.71809457
110Intention tremor (HP:0002080)1.71533937
111Acute necrotizing encephalopathy (HP:0006965)1.71453611
112Myokymia (HP:0002411)1.71147735
113Depression (HP:0000716)1.70723966
114Focal seizures (HP:0007359)1.70495339
115Hyperinsulinemic hypoglycemia (HP:0000825)1.69679943
116Lower limb amyotrophy (HP:0007210)1.69415232
117Proximal amyotrophy (HP:0007126)1.68587817
118Distal lower limb muscle weakness (HP:0009053)1.67626900
119Central scotoma (HP:0000603)1.66664788
120Muscular dystrophy (HP:0003560)1.66189039
121Achilles tendon contracture (HP:0001771)1.66008209
122Abnormality of the ischium (HP:0003174)1.65516968
123Generalized muscle weakness (HP:0003324)1.64862237
124Termporal pattern (HP:0011008)1.64536551
125Insidious onset (HP:0003587)1.64536551
126Cerebral inclusion bodies (HP:0100314)1.63534057
127Cerebral hemorrhage (HP:0001342)1.63336918
128Tinnitus (HP:0000360)1.62494433
129Broad-based gait (HP:0002136)1.62150567
130Congestive heart failure (HP:0001635)1.61915147
131Impaired social interactions (HP:0000735)1.61796150
132Abnormal social behavior (HP:0012433)1.61796150
133Upper limb amyotrophy (HP:0009129)1.61257756
134Distal upper limb amyotrophy (HP:0007149)1.61257756
135Shallow orbits (HP:0000586)1.61003086
136Areflexia of lower limbs (HP:0002522)1.60743861
137Lymphangioma (HP:0100764)1.60732999
138Bradycardia (HP:0001662)1.59594761

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN4.23452059
2PHKG13.22676307
3PHKG23.22676307
4LMTK23.00950809
5RIPK12.83160268
6TRIB32.77225806
7PDK32.68947823
8PDK42.68947823
9DMPK2.52167076
10MYLK2.42929833
11OBSCN2.40975527
12ARAF2.14973769
13PKN22.12482204
14WNK12.06510827
15PRPF4B1.90665687
16TIE11.87445871
17PINK11.85313644
18CAMKK21.75641202
19PDK21.75424131
20STK381.65105777
21PIK3CA1.60929404
22EPHA41.59691337
23WNK41.51773241
24PRKD31.45646372
25PAK31.43514409
26GRK51.42923536
27CAMK2D1.38565417
28EPHB11.36101122
29BCKDK1.36080006
30NEK11.35305336
31STK391.32324760
32PAK61.31032292
33CAMKK11.26573664
34PTK61.25686520
35PRKD11.24493368
36MAP3K121.24043706
37KSR11.23967869
38CDC42BPA1.21465624
39MAP3K91.19775756
40EEF2K1.19343666
41PDGFRA1.09815849
42LIMK11.08480729
43MAP3K41.07147505
44PRKCH1.02995503
45MAP3K71.00917033
46MOS1.00866203
47PIK3CG0.99262547
48ICK0.99055166
49MAP2K40.97845201
50KSR20.94889813
51MAPK120.92583580
52BRAF0.92384249
53MUSK0.92005382
54MAP3K130.91621336
55CAMK40.91483876
56TESK10.89807791
57ROCK20.89236511
58CAMK1G0.88654063
59PDPK10.87993506
60NTRK30.87008815
61PTK2B0.84038405
62STK240.83601837
63CAMK10.83237997
64ROCK10.82786523
65DDR20.82774241
66PRKAA10.81678200
67RET0.79806815
68CAMK2G0.79654000
69CAMK2A0.79428989
70PKN10.78298861
71RAF10.77536928
72ILK0.74714667
73PDK10.74589044
74LATS20.70033020
75PAK20.69975433
76MAP3K60.69901072
77STK110.69357895
78PRKAA20.68892336
79DAPK30.68553928
80SGK30.68011023
81GRK70.67627152
82MAP3K30.66754779
83NEK90.66126145
84MAP2K10.65743811
85SGK2230.64226572
86SGK4940.64226572
87SMG10.64070572
88TGFBR20.62179241
89PTK20.61670898
90TYRO30.61224497
91MINK10.60300939
92FER0.59838985
93OXSR10.59735166
94IRAK20.57792584
95INSRR0.57105736
96PAK40.55633254
97NTRK10.54449032
98MAP2K30.54236530
99CAMK2B0.53052034
100DAPK20.53018273
101AKT30.52916333
102PRKCE0.51938501
103PRKACB0.51832944
104DYRK1B0.51108575
105EPHB20.50929773
106RPS6KA20.50110827
107MTOR0.49252412
108ALK0.48700082
109UHMK10.48528509
110CDK50.48058218
111TAOK20.47836299
112NTRK20.47628416
113MAPK40.46872773
114PRKACA0.46398912
115MAPK100.45892300
116CDK150.45022605
117CAMK1D0.44943265
118PRKACG0.44891641
119SIK10.44719869
120CDK180.44251021
121SGK10.43996476
122TAOK10.43572289
123MAP3K10.42372696
124TRPM70.42116805
125PRKG10.41776761
126MAP3K20.41328443
127MAPK70.40996117
128AKT20.40896885
129SGK20.39613575
130PRKG20.38748876
131MARK20.38551023
132PNCK0.37998231
133RPS6KA30.37844608
134PDGFRB0.36466421
135MARK10.36278805
136PRKCG0.33047207

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.73252965
2Cardiac muscle contraction_Homo sapiens_hsa042603.10292171
3Dilated cardiomyopathy_Homo sapiens_hsa054142.82068637
42-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.66235132
5Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.53102908
6Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.12918732
7Propanoate metabolism_Homo sapiens_hsa006402.02498913
8Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.99767808
9Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.97663889
10Fatty acid degradation_Homo sapiens_hsa000711.75293910
11Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.59081693
12Circadian entrainment_Homo sapiens_hsa047131.54407103
13Nicotine addiction_Homo sapiens_hsa050331.52963822
14Gastric acid secretion_Homo sapiens_hsa049711.52319041
15Parkinsons disease_Homo sapiens_hsa050121.50639053
16Fatty acid metabolism_Homo sapiens_hsa012121.50224586
17Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.50130742
18Long-term potentiation_Homo sapiens_hsa047201.45920893
19Alzheimers disease_Homo sapiens_hsa050101.44775574
20Oxidative phosphorylation_Homo sapiens_hsa001901.44488669
21Glutamatergic synapse_Homo sapiens_hsa047241.41980469
22Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.41386706
23Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.40643878
24Carbon metabolism_Homo sapiens_hsa012001.38229677
25Salivary secretion_Homo sapiens_hsa049701.34264755
26cGMP-PKG signaling pathway_Homo sapiens_hsa040221.33997206
27GABAergic synapse_Homo sapiens_hsa047271.32110505
28Type II diabetes mellitus_Homo sapiens_hsa049301.29940899
29Insulin secretion_Homo sapiens_hsa049111.28565229
30Taste transduction_Homo sapiens_hsa047421.25965719
31Aldosterone synthesis and secretion_Homo sapiens_hsa049251.23964274
32Glioma_Homo sapiens_hsa052141.22734382
33Oxytocin signaling pathway_Homo sapiens_hsa049211.22331010
34Butanoate metabolism_Homo sapiens_hsa006501.21408718
35Calcium signaling pathway_Homo sapiens_hsa040201.20921085
36Renin secretion_Homo sapiens_hsa049241.20268470
37Morphine addiction_Homo sapiens_hsa050321.18523686
38Long-term depression_Homo sapiens_hsa047301.18038070
39Nitrogen metabolism_Homo sapiens_hsa009101.09191966
40Pyruvate metabolism_Homo sapiens_hsa006201.08061833
41Prion diseases_Homo sapiens_hsa050201.03899909
42cAMP signaling pathway_Homo sapiens_hsa040241.03063861
43Vascular smooth muscle contraction_Homo sapiens_hsa042701.01804090
44Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.01574574
45Pancreatic secretion_Homo sapiens_hsa049720.99233701
46Endometrial cancer_Homo sapiens_hsa052130.98937711
47Pentose phosphate pathway_Homo sapiens_hsa000300.98654100
48Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.97922295
49Adherens junction_Homo sapiens_hsa045200.96363625
50Platelet activation_Homo sapiens_hsa046110.96054061
51Glucagon signaling pathway_Homo sapiens_hsa049220.95813255
52Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.95435412
53Bile secretion_Homo sapiens_hsa049760.95092888
54Amphetamine addiction_Homo sapiens_hsa050310.94394837
55Cholinergic synapse_Homo sapiens_hsa047250.92671886
56Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.91650981
57PPAR signaling pathway_Homo sapiens_hsa033200.91173538
58Huntingtons disease_Homo sapiens_hsa050160.88692777
59Gap junction_Homo sapiens_hsa045400.87220358
60ErbB signaling pathway_Homo sapiens_hsa040120.87149116
61Dopaminergic synapse_Homo sapiens_hsa047280.86615965
62Insulin resistance_Homo sapiens_hsa049310.86374316
63Synaptic vesicle cycle_Homo sapiens_hsa047210.85418592
64Adipocytokine signaling pathway_Homo sapiens_hsa049200.84877364
65Neurotrophin signaling pathway_Homo sapiens_hsa047220.84828654
66Arginine biosynthesis_Homo sapiens_hsa002200.84790916
67Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.84468417
68Estrogen signaling pathway_Homo sapiens_hsa049150.83670050
69GnRH signaling pathway_Homo sapiens_hsa049120.83227537
70Choline metabolism in cancer_Homo sapiens_hsa052310.80006978
71Fatty acid biosynthesis_Homo sapiens_hsa000610.79446065
72AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.79090684
73Non-small cell lung cancer_Homo sapiens_hsa052230.78916444
74Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.77928940
75Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.77430259
76Focal adhesion_Homo sapiens_hsa045100.77268802
77Arginine and proline metabolism_Homo sapiens_hsa003300.76772074
78Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.75678073
79Leukocyte transendothelial migration_Homo sapiens_hsa046700.75593300
80Fatty acid elongation_Homo sapiens_hsa000620.75045440
81Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.72674475
82Insulin signaling pathway_Homo sapiens_hsa049100.70856012
83Thyroid hormone synthesis_Homo sapiens_hsa049180.70267335
84Olfactory transduction_Homo sapiens_hsa047400.70183510
85Regulation of actin cytoskeleton_Homo sapiens_hsa048100.69946543
86mTOR signaling pathway_Homo sapiens_hsa041500.69813549
87Dorso-ventral axis formation_Homo sapiens_hsa043200.69785245
88Tight junction_Homo sapiens_hsa045300.68992903
89Rap1 signaling pathway_Homo sapiens_hsa040150.68586119
90Chronic myeloid leukemia_Homo sapiens_hsa052200.68512212
91Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.68059962
92MAPK signaling pathway_Homo sapiens_hsa040100.68012637
93Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.67575186
94Carbohydrate digestion and absorption_Homo sapiens_hsa049730.65468294
95AMPK signaling pathway_Homo sapiens_hsa041520.64509544
96Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.63802666
97ECM-receptor interaction_Homo sapiens_hsa045120.62974634
98Fructose and mannose metabolism_Homo sapiens_hsa000510.62670806
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62577202
100Longevity regulating pathway - mammal_Homo sapiens_hsa042110.60725235
101Viral myocarditis_Homo sapiens_hsa054160.60178296
102Phospholipase D signaling pathway_Homo sapiens_hsa040720.58810997
103* Phosphatidylinositol signaling system_Homo sapiens_hsa040700.58694152
104Endocytosis_Homo sapiens_hsa041440.57423036
105HIF-1 signaling pathway_Homo sapiens_hsa040660.56243985
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.56149445
107Axon guidance_Homo sapiens_hsa043600.54125887
108Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.53263734
109* Inositol phosphate metabolism_Homo sapiens_hsa005620.52352284
110Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.51824926
111Biosynthesis of amino acids_Homo sapiens_hsa012300.51586211
112Circadian rhythm_Homo sapiens_hsa047100.51451429
113Lysine degradation_Homo sapiens_hsa003100.50314183
114Amoebiasis_Homo sapiens_hsa051460.49761277
115Melanogenesis_Homo sapiens_hsa049160.48956157
116Serotonergic synapse_Homo sapiens_hsa047260.48842681
117Starch and sucrose metabolism_Homo sapiens_hsa005000.48664491
118Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.47498005
119Cocaine addiction_Homo sapiens_hsa050300.47139256
120Proteoglycans in cancer_Homo sapiens_hsa052050.46722178
121Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46369924
122VEGF signaling pathway_Homo sapiens_hsa043700.45675557
123Renal cell carcinoma_Homo sapiens_hsa052110.45362814
124Protein digestion and absorption_Homo sapiens_hsa049740.42918249
125Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.41645196
126Ovarian steroidogenesis_Homo sapiens_hsa049130.41601280
127Glycerolipid metabolism_Homo sapiens_hsa005610.41441546
128Central carbon metabolism in cancer_Homo sapiens_hsa052300.40805577
129Tryptophan metabolism_Homo sapiens_hsa003800.38847042
130Mineral absorption_Homo sapiens_hsa049780.38577330

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