IPCEF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of cell killing (GO:0031342)7.48262145
2negative regulation of leukocyte mediated cytotoxicity (GO:0001911)7.48262145
3negative T cell selection (GO:0043383)5.98604953
4negative thymic T cell selection (GO:0045060)5.74771430
5positive T cell selection (GO:0043368)5.45983735
6antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.34154411
7positive regulation of gamma-delta T cell activation (GO:0046645)5.20366386
8positive thymic T cell selection (GO:0045059)5.00096160
9regulation of isotype switching to IgG isotypes (GO:0048302)4.96420900
10synaptic vesicle docking involved in exocytosis (GO:0016081)4.85344959
11response to interleukin-15 (GO:0070672)4.79874620
12cellular response to interleukin-15 (GO:0071350)4.73758347
13T cell selection (GO:0045058)4.68929937
14positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.67062401
15thymic T cell selection (GO:0045061)4.60295003
16synaptic vesicle exocytosis (GO:0016079)4.46787158
17interferon-gamma production (GO:0032609)4.37844320
18glutamate secretion (GO:0014047)4.36307391
19positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.35671597
20regulation of gamma-delta T cell differentiation (GO:0045586)4.29616418
21activated T cell proliferation (GO:0050798)4.17777684
22synaptic vesicle maturation (GO:0016188)4.17540101
23negative regulation of T cell mediated immunity (GO:0002710)4.16411337
24leukocyte aggregation (GO:0070486)4.03150813
25modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.03112370
26positive regulation by organism of defense response of other organism involved in symbiotic interact4.03112370
27modulation by symbiont of host immune response (GO:0052553)4.03112370
28positive regulation by symbiont of host defense response (GO:0052509)4.03112370
29modulation by symbiont of host defense response (GO:0052031)4.03112370
30modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.03112370
31regulation of synaptic vesicle exocytosis (GO:2000300)4.00487328
32regulation of B cell receptor signaling pathway (GO:0050855)4.00176837
33T cell receptor signaling pathway (GO:0050852)3.99185784
34positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.96953877
35regulation of regulatory T cell differentiation (GO:0045589)3.95043769
36locomotory exploration behavior (GO:0035641)3.93220274
37regulation of short-term neuronal synaptic plasticity (GO:0048172)3.92554670
38regulation of gamma-delta T cell activation (GO:0046643)3.90439324
39T cell migration (GO:0072678)3.79796787
40regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.72045134
41antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.63582155
42antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.63582155
43macrophage activation involved in immune response (GO:0002281)3.61428936
44T cell costimulation (GO:0031295)3.59469436
45neuronal action potential propagation (GO:0019227)3.58622021
46lymphocyte costimulation (GO:0031294)3.53485007
47microglial cell activation (GO:0001774)3.53469231
48vocalization behavior (GO:0071625)3.51868551
49ionotropic glutamate receptor signaling pathway (GO:0035235)3.50313827
50regulation of synaptic vesicle transport (GO:1902803)3.49110119
51regulation of T cell tolerance induction (GO:0002664)3.48076837
52negative regulation of leukocyte mediated immunity (GO:0002704)3.47341651
53regulation of glutamate receptor signaling pathway (GO:1900449)3.42322131
54antigen receptor-mediated signaling pathway (GO:0050851)3.38843177
55cellular extravasation (GO:0045123)3.38142741
56detection of other organism (GO:0098543)3.33350308
57negative regulation of lymphocyte mediated immunity (GO:0002707)3.29754006
58positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.29565949
59cerebellar Purkinje cell differentiation (GO:0021702)3.23726480
60regulation of B cell differentiation (GO:0045577)3.21129377
61antigen processing and presentation of endogenous antigen (GO:0019883)3.18207316
62mast cell degranulation (GO:0043303)3.18007128
63mast cell activation involved in immune response (GO:0002279)3.18007128
64regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.17815505
65neutrophil activation involved in immune response (GO:0002283)3.16459750
66detection of bacterium (GO:0016045)3.15868615
67glutamate receptor signaling pathway (GO:0007215)3.15728647
68regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.15191122
69mast cell activation (GO:0045576)3.14436038
70positive regulation of granulocyte differentiation (GO:0030854)3.14296757
71regulation of ARF protein signal transduction (GO:0032012)3.12859863
72positive regulation of B cell differentiation (GO:0045579)3.12837007
73myeloid cell activation involved in immune response (GO:0002275)3.12393695
74detection of molecule of bacterial origin (GO:0032490)3.11473490
75negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.11308429
76protein localization to synapse (GO:0035418)3.09666061
77long-term synaptic potentiation (GO:0060291)3.08655288
78synaptic transmission, glutamatergic (GO:0035249)3.08496750
79regulation of alpha-beta T cell proliferation (GO:0046640)3.06018400
80negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.05952033
81neurotransmitter secretion (GO:0007269)3.05151259
82cellular potassium ion homeostasis (GO:0030007)3.04311128
83signal complex assembly (GO:0007172)3.03883440
84gamma-aminobutyric acid signaling pathway (GO:0007214)3.02901541
85G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.01886984
86regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.00741926
87regulation of interleukin-12 biosynthetic process (GO:0045075)3.00609559
88detection of external biotic stimulus (GO:0098581)2.98213643
89negative regulation of interleukin-12 production (GO:0032695)2.97829795
90regulation of tolerance induction (GO:0002643)2.97060747
91positive regulation of membrane potential (GO:0045838)2.96638195
92positive regulation of mast cell activation (GO:0033005)2.95669373
93response to muramyl dipeptide (GO:0032495)2.95273972
94regulation of excitatory postsynaptic membrane potential (GO:0060079)2.92481856
95regulation of T cell mediated cytotoxicity (GO:0001914)2.91505408
96antigen processing and presentation via MHC class Ib (GO:0002475)2.91376986
97neuron cell-cell adhesion (GO:0007158)2.90202021
98negative regulation of adaptive immune response (GO:0002820)2.88139788
99neuron-neuron synaptic transmission (GO:0007270)2.87323828
100immunoglobulin mediated immune response (GO:0016064)2.87009785
101regulation of interleukin-2 biosynthetic process (GO:0045076)2.86992993
102interferon-gamma-mediated signaling pathway (GO:0060333)2.86444206
103regulation of interferon-beta biosynthetic process (GO:0045357)2.83248050
104response to host immune response (GO:0052572)2.82981574
105response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.82981574
106macrophage activation (GO:0042116)2.82906430
107neutrophil activation (GO:0042119)2.80914570
108long-term memory (GO:0007616)2.80178204
109positive regulation of interleukin-2 production (GO:0032743)2.79597887
110tolerance induction (GO:0002507)2.79411305
111regulation of defense response to virus by virus (GO:0050690)2.78914258
112positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.77994256
113response to peptidoglycan (GO:0032494)2.77079796
114regulation of T cell receptor signaling pathway (GO:0050856)2.76786691
115type I interferon signaling pathway (GO:0060337)2.76680748
116cellular response to type I interferon (GO:0071357)2.76680748
117positive regulation of humoral immune response (GO:0002922)2.75855426
118response to type I interferon (GO:0034340)2.74324889
119regulation of long-term neuronal synaptic plasticity (GO:0048169)2.73561974
120positive regulation of alpha-beta T cell proliferation (GO:0046641)2.73299261
121regulation of leukocyte mediated cytotoxicity (GO:0001910)2.72644483
122negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.72351777
123neurotransmitter-gated ion channel clustering (GO:0072578)2.72226391
124regulation of postsynaptic membrane potential (GO:0060078)2.72011147
125leukocyte degranulation (GO:0043299)2.71223723
126exploration behavior (GO:0035640)2.71007474
127positive regulation of isotype switching (GO:0045830)2.70010952
128positive regulation of tolerance induction (GO:0002645)2.69161277
129G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.66790806
130detection of biotic stimulus (GO:0009595)2.66719962
131regulation of synaptic plasticity (GO:0048167)2.66664253
132regulation of isotype switching (GO:0045191)2.66316698
133sodium ion export (GO:0071436)2.65152862
134positive regulation of neurotransmitter secretion (GO:0001956)2.64646810
135respiratory burst (GO:0045730)2.62127998
136regulation of neuronal synaptic plasticity (GO:0048168)2.62028145
137G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.61683282
138positive regulation of natural killer cell mediated immunity (GO:0002717)2.60783445
139B cell receptor signaling pathway (GO:0050853)2.59577350
140regulation of natural killer cell mediated immunity (GO:0002715)2.59211136
141regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.59211136
142B cell homeostasis (GO:0001782)2.59038862
143response to histamine (GO:0034776)2.58507705
144alpha-beta T cell differentiation (GO:0046632)2.57374220
145positive regulation of Rap GTPase activity (GO:0032854)2.57359835
146regulation of neurotransmitter secretion (GO:0046928)2.56882245
147positive regulation of interleukin-4 production (GO:0032753)2.55484486
148negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.55179672
149immune response-activating cell surface receptor signaling pathway (GO:0002429)2.54184730

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.27128723
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human5.25164181
3EZH2_22144423_ChIP-Seq_EOC_Human4.23169416
4RUNX_20019798_ChIP-Seq_JUKART_Human3.14937394
5SMAD_19615063_ChIP-ChIP_OVARY_Human3.00606420
6FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.74309741
7STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.68325171
8VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.52065838
9SCL_19346495_ChIP-Seq_HPC-7_Human2.44009183
10GBX2_23144817_ChIP-Seq_PC3_Human2.30522974
11IKZF1_21737484_ChIP-ChIP_HCT116_Human2.25989964
12RARB_27405468_Chip-Seq_BRAIN_Mouse2.25736501
13* DROSHA_22980978_ChIP-Seq_HELA_Human2.21380691
14BP1_19119308_ChIP-ChIP_Hs578T_Human2.17353775
15AR_21572438_ChIP-Seq_LNCaP_Human2.16882454
16MYB_21317192_ChIP-Seq_ERMYB_Mouse2.12486507
17BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.00991437
18* REST_21632747_ChIP-Seq_MESCs_Mouse1.93153878
19MYB_26560356_Chip-Seq_TH2_Human1.93080735
20MYC_22102868_ChIP-Seq_BL_Human1.90212636
21* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.88091857
22SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.87147563
23IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.81619897
24JARID2_20064375_ChIP-Seq_MESCs_Mouse1.79906034
25STAT4_19710469_ChIP-ChIP_TH1__Mouse1.76376633
26SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.73942891
27MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.73608425
28GATA1_22025678_ChIP-Seq_K562_Human1.72584195
29* IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.69608049
30EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.67866826
31TAF15_26573619_Chip-Seq_HEK293_Human1.67649675
32SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.67093520
33SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.66025570
34* SPI1_23547873_ChIP-Seq_NB4_Human1.64921988
35MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.64436401
36REST_18959480_ChIP-ChIP_MESCs_Mouse1.59456832
37VDR_24763502_ChIP-Seq_THP-1_Human1.57415507
38LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.52658805
39SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.52007205
40Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.51674591
41GATA3_27048872_Chip-Seq_THYMUS_Human1.46649935
42KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.46621452
43SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.45122502
44UTX_26944678_Chip-Seq_JUKART_Human1.44768028
45MYB_26560356_Chip-Seq_TH1_Human1.44182019
46GATA1_19941827_ChIP-Seq_MEL_Mouse1.43837437
47MAF_26560356_Chip-Seq_TH1_Human1.43309148
48EZH2_18974828_ChIP-Seq_MESCs_Mouse1.42508856
49RNF2_18974828_ChIP-Seq_MESCs_Mouse1.42508856
50MTF2_20144788_ChIP-Seq_MESCs_Mouse1.42281718
51KDM2B_26808549_Chip-Seq_SUP-B15_Human1.42233102
52RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.41171925
53* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.38324593
54PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.37519719
55SMAD4_21799915_ChIP-Seq_A2780_Human1.36374589
56PRDM14_20953172_ChIP-Seq_ESCs_Human1.35104660
57KDM2B_26808549_Chip-Seq_DND41_Human1.33195229
58NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.32996707
59TCF7_22412390_ChIP-Seq_EML_Mouse1.32558498
60TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.30940801
61* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.29850145
62GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.27679189
63MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.27586140
64E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.27381300
65LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.25916832
66RNF2_27304074_Chip-Seq_ESCs_Mouse1.22916359
67SUZ12_27294783_Chip-Seq_ESCs_Mouse1.22287060
68* SPI1_23127762_ChIP-Seq_K562_Human1.21892603
69SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.19260090
70RXR_22108803_ChIP-Seq_LS180_Human1.18560031
71KDM2B_26808549_Chip-Seq_JURKAT_Human1.17693536
72SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.17135544
73GATA1_19941826_ChIP-Seq_K562_Human1.16892975
74DNAJC2_21179169_ChIP-ChIP_NT2_Human1.15930086
75IRF8_22096565_ChIP-ChIP_GC-B_Human1.14483288
76JARID2_20075857_ChIP-Seq_MESCs_Mouse1.14303420
77TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13143345
78KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.13052399
79VDR_21846776_ChIP-Seq_THP-1_Human1.11853411
80* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.11590562
81CTBP2_25329375_ChIP-Seq_LNCAP_Human1.11577729
82IRF8_27001747_Chip-Seq_BMDM_Mouse1.10922235
83STAT3_23295773_ChIP-Seq_U87_Human1.10009407
84RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.09486646
85AR_25329375_ChIP-Seq_VCAP_Human1.09460003
86* PU_27001747_Chip-Seq_BMDM_Mouse1.09065507
87ZFP57_27257070_Chip-Seq_ESCs_Mouse1.08717219
88SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07166843
89NOTCH1_21737748_ChIP-Seq_TLL_Human1.07004836
90ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.06035558
91FLI1_27457419_Chip-Seq_LIVER_Mouse1.05896685
92IRF8_21731497_ChIP-ChIP_J774_Mouse1.05190506
93TP53_16413492_ChIP-PET_HCT116_Human1.02581213
94* P300_19829295_ChIP-Seq_ESCs_Human1.01306519
95TCF4_23295773_ChIP-Seq_U87_Human1.01233209
96* NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.00501577
97AR_19668381_ChIP-Seq_PC3_Human1.00343851
98PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00171284
99EZH2_27294783_Chip-Seq_ESCs_Mouse0.98344403
100SOX2_21211035_ChIP-Seq_LN229_Gbm0.96574851
101POU3F2_20337985_ChIP-ChIP_501MEL_Human0.96010383
102GATA3_26560356_Chip-Seq_TH2_Human0.95868808
103VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.95755597
104GATA2_21666600_ChIP-Seq_HMVEC_Human0.95340336
105PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.95329824
106NR3C1_23031785_ChIP-Seq_PC12_Mouse0.94844718
107TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94556245
108POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.94556245
109GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.92632000
110CTBP1_25329375_ChIP-Seq_LNCAP_Human0.91870636
111EZH2_27304074_Chip-Seq_ESCs_Mouse0.91734486
112* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91732500
113BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.91655598
114MAF_26560356_Chip-Seq_TH2_Human0.91452408
115TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.91447589
116P53_22127205_ChIP-Seq_FIBROBLAST_Human0.90244900
117GATA2_19941826_ChIP-Seq_K562_Human0.90127776
118NANOG_18555785_Chip-Seq_ESCs_Mouse0.89413678
119CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.88172919
120SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.88018572
121* KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.87726158
122THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.87177540
123* SMRT_27268052_Chip-Seq_Bcells_Human0.86711061
124EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.86182321
125RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.85618041
126GATA1_19941827_ChIP-Seq_MEL86_Mouse0.84885124
127GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.84630299
128ZNF217_24962896_ChIP-Seq_MCF-7_Human0.83377309
129TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.82824149
130* CTNNB1_20460455_ChIP-Seq_HCT116_Human0.81685111
131RUNX1_22412390_ChIP-Seq_EML_Mouse0.80908522
132VDR_24787735_ChIP-Seq_THP-1_Human0.80548594
133* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.79903315
134* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.78700870
135* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.74511195
136GATA3_26560356_Chip-Seq_TH1_Human0.71958168
137TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.67797632
138CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.66314467

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.27214873
2MP0003763_abnormal_thymus_physiology3.71970700
3MP0003880_abnormal_central_pattern3.38018467
4MP0003635_abnormal_synaptic_transmissio3.31289207
5MP0005671_abnormal_response_to2.93924636
6MP0009745_abnormal_behavioral_response2.70451619
7MP0002064_seizures2.55139036
8MP0002063_abnormal_learning/memory/cond2.54315327
9MP0001968_abnormal_touch/_nociception2.47163312
10MP0009046_muscle_twitch2.34566540
11MP0004270_analgesia2.29754758
12MP0008569_lethality_at_weaning2.29083546
13MP0003787_abnormal_imprinting2.24567792
14MP0004510_myositis2.24249938
15MP0002572_abnormal_emotion/affect_behav2.24185542
16MP0000685_abnormal_immune_system2.16925548
17MP0001501_abnormal_sleep_pattern2.16141661
18MP0003303_peritoneal_inflammation2.03783939
19MP0002736_abnormal_nociception_after2.02994840
20MP0001800_abnormal_humoral_immune1.97381962
21MP0002398_abnormal_bone_marrow1.84421155
22MP0001835_abnormal_antigen_presentation1.84209331
23MP0001486_abnormal_startle_reflex1.84123255
24MP0002822_catalepsy1.83924388
25MP0005387_immune_system_phenotype1.83443095
26MP0001790_abnormal_immune_system1.83443095
27MP0002420_abnormal_adaptive_immunity1.83376814
28MP0002272_abnormal_nervous_system1.81642395
29MP0005423_abnormal_somatic_nervous1.80911045
30MP0001819_abnormal_immune_cell1.80530018
31MP0000703_abnormal_thymus_morphology1.79877378
32MP0005000_abnormal_immune_tolerance1.76984311
33MP0003690_abnormal_glial_cell1.76682258
34MP0008961_abnormal_basal_metabolism1.73677443
35MP0002735_abnormal_chemical_nociception1.73066599
36MP0002723_abnormal_immune_serum1.72940574
37MP0003866_abnormal_defecation1.69232253
38MP0002734_abnormal_mechanical_nocicepti1.64730620
39MP0004381_abnormal_hair_follicle1.59404040
40MP0001873_stomach_inflammation1.58186064
41MP0003879_abnormal_hair_cell1.56682074
42MP0000716_abnormal_immune_system1.53935275
43MP0003172_abnormal_lysosome_physiology1.52601472
44MP0002067_abnormal_sensory_capabilities1.51726355
45MP0001440_abnormal_grooming_behavior1.51187817
46MP0003183_abnormal_peptide_metabolism1.51002793
47MP0005310_abnormal_salivary_gland1.49501691
48MP0002452_abnormal_antigen_presenting1.48945047
49MP0003436_decreased_susceptibility_to1.47622515
50MP0003300_gastrointestinal_ulcer1.46758083
51MP0001970_abnormal_pain_threshold1.43661556
52MP0002405_respiratory_system_inflammati1.41560007
53MP0002166_altered_tumor_susceptibility1.40350188
54MP0002006_tumorigenesis1.39345727
55MP0004924_abnormal_behavior1.37303709
56MP0005386_behavior/neurological_phenoty1.37303709
57MP0001533_abnormal_skeleton_physiology1.35442190
58MP0000569_abnormal_digit_pigmentation1.34858000
59MP0002722_abnormal_immune_system1.31962788
60MP0009785_altered_susceptibility_to1.30746573
61MP0002396_abnormal_hematopoietic_system1.30418196
62MP0001348_abnormal_lacrimal_gland1.27590526
63MP0002733_abnormal_thermal_nociception1.25077062
64MP0000689_abnormal_spleen_morphology1.23862270
65MP0006082_CNS_inflammation1.23329515
66MP0004811_abnormal_neuron_physiology1.23093152
67MP0009333_abnormal_splenocyte_physiolog1.22599536
68MP0008874_decreased_physiological_sensi1.21067319
69MP0005025_abnormal_response_to1.20201124
70MP0003633_abnormal_nervous_system1.18942318
71MP0000920_abnormal_myelination1.17854172
72MP0002429_abnormal_blood_cell1.12957098
73MP0008260_abnormal_autophagy1.12956494
74MP0002557_abnormal_social/conspecific_i1.12371292
75MP0004130_abnormal_muscle_cell1.11456977
76MP0000015_abnormal_ear_pigmentation1.08989241
77MP0008872_abnormal_physiological_respon1.06292606
78MP0003329_amyloid_beta_deposits1.05812438
79MP0005075_abnormal_melanosome_morpholog1.04866761
80MP0002419_abnormal_innate_immunity1.02992505
81MP0010155_abnormal_intestine_physiology1.02513358
82MP0002009_preneoplasia1.00920206
83MP0002184_abnormal_innervation1.00738527
84MP0001986_abnormal_taste_sensitivity0.97412809
85MP0003828_pulmonary_edema0.96701671
86MP0004808_abnormal_hematopoietic_stem0.96446270
87MP0004947_skin_inflammation0.95326121
88MP0002998_abnormal_bone_remodeling0.94382836
89MP0004742_abnormal_vestibular_system0.93189191
90MP0001851_eye_inflammation0.93019735
91MP0004883_abnormal_blood_vessel0.92810732
92MP0001502_abnormal_circadian_rhythm0.92787517
93MP0008877_abnormal_DNA_methylation0.92675587
94MP0009764_decreased_sensitivity_to0.90453157
95MP0001905_abnormal_dopamine_level0.89477759
96MP0000604_amyloidosis0.88746335
97MP0008469_abnormal_protein_level0.88476943
98MP0002066_abnormal_motor_capabilities/c0.88284773
99MP0002148_abnormal_hypersensitivity_rea0.88002826
100MP0003045_fibrosis0.87830666
101MP0005166_decreased_susceptibility_to0.87450440
102MP0005646_abnormal_pituitary_gland0.87368576
103MP0003631_nervous_system_phenotype0.86804211
104MP0001845_abnormal_inflammatory_respons0.85141041
105MP0005464_abnormal_platelet_physiology0.83785178
106MP0004484_altered_response_of0.82499580
107MP0002277_abnormal_respiratory_mucosa0.80593017
108MP0001984_abnormal_olfaction0.79435382
109MP0009780_abnormal_chondrocyte_physiolo0.78924472
110MP0003724_increased_susceptibility_to0.77556051
111MP0005174_abnormal_tail_pigmentation0.77109069
112MP0001853_heart_inflammation0.75220838
113MP0001765_abnormal_ion_homeostasis0.74155485
114MP0003191_abnormal_cellular_cholesterol0.74131240
115MP0008004_abnormal_stomach_pH0.72463929
116MP0003075_altered_response_to0.72294328
117MP0002933_joint_inflammation0.70377639
118MP0005645_abnormal_hypothalamus_physiol0.70073150
119MP0009278_abnormal_bone_marrow0.69378091
120MP0000858_altered_metastatic_potential0.68912512
121MP0000955_abnormal_spinal_cord0.68726601
122MP0005535_abnormal_body_temperature0.65374545
123MP0004142_abnormal_muscle_tone0.64962318
124MP0000778_abnormal_nervous_system0.64217057
125MP0002882_abnormal_neuron_morphology0.62899083
126MP0000465_gastrointestinal_hemorrhage0.60579344

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.35737940
2T lymphocytopenia (HP:0005403)5.09465093
3Abnormality of T cell number (HP:0011839)4.82441489
4Focal seizures (HP:0007359)4.55996470
5Atonic seizures (HP:0010819)4.51296213
6Recurrent bacterial skin infections (HP:0005406)4.49927002
7Stomatitis (HP:0010280)4.18672400
8Febrile seizures (HP:0002373)4.16829007
9Epileptic encephalopathy (HP:0200134)4.01862656
10Orchitis (HP:0100796)3.91196783
11Visual hallucinations (HP:0002367)3.82704979
12Dysmetric saccades (HP:0000641)3.74544050
13Myokymia (HP:0002411)3.69647469
14Panhypogammaglobulinemia (HP:0003139)3.56991604
15Gastrointestinal infarctions (HP:0005244)3.53944466
16Progressive cerebellar ataxia (HP:0002073)3.46894463
17Severe combined immunodeficiency (HP:0004430)3.46567762
18Recurrent fungal infections (HP:0002841)3.46370666
19Gaze-evoked nystagmus (HP:0000640)3.46017308
20Abnormality of macrophages (HP:0004311)3.44663306
21Broad-based gait (HP:0002136)3.43289173
22Spontaneous hematomas (HP:0007420)3.41062554
23Absence seizures (HP:0002121)3.37723351
24Vasculitis (HP:0002633)3.31545113
25Recurrent skin infections (HP:0001581)3.30318182
26Chronic mucocutaneous candidiasis (HP:0002728)3.29429700
27Recurrent cutaneous fungal infections (HP:0011370)3.29429700
28Abnormality of T cells (HP:0002843)3.25129023
29Impaired smooth pursuit (HP:0007772)3.19218594
30Abnormality of binocular vision (HP:0011514)3.12009127
31Diplopia (HP:0000651)3.12009127
32Dialeptic seizures (HP:0011146)3.10758018
33Abnormal delayed hypersensitivity skin test (HP:0002963)3.07707622
34Prolonged bleeding time (HP:0003010)3.07461307
35Combined immunodeficiency (HP:0005387)3.05379064
36Chronic otitis media (HP:0000389)3.04832159
37Recurrent viral infections (HP:0004429)2.97369632
38Papilledema (HP:0001085)2.96817104
39Impaired vibration sensation in the lower limbs (HP:0002166)2.96050275
40Keratoconjunctivitis sicca (HP:0001097)2.93440311
41Keratoconjunctivitis (HP:0001096)2.92004652
42Abnormality of the fingertips (HP:0001211)2.86385035
43Recurrent gram-negative bacterial infections (HP:0005420)2.85118788
44Postural instability (HP:0002172)2.85058175
45Genetic anticipation (HP:0003743)2.83122590
46Chest pain (HP:0100749)2.79783938
47Recurrent bronchitis (HP:0002837)2.79642864
48Leukocytosis (HP:0001974)2.78276393
49Abnormality of ocular smooth pursuit (HP:0000617)2.77232123
50Epistaxis (HP:0000421)2.76866713
51Thyroiditis (HP:0100646)2.76053350
52Gingival bleeding (HP:0000225)2.76037897
53Truncal ataxia (HP:0002078)2.75373503
54Nasal polyposis (HP:0100582)2.74675775
55Eczematoid dermatitis (HP:0000976)2.73891356
56B lymphocytopenia (HP:0010976)2.73419836
57Abnormality of B cell number (HP:0010975)2.73419836
58Hemoptysis (HP:0002105)2.72043396
59Increased IgM level (HP:0003496)2.70072801
60Slow saccadic eye movements (HP:0000514)2.67665245
61IgG deficiency (HP:0004315)2.66855830
62Abnormal hair whorl (HP:0010721)2.63689994
63Generalized tonic-clonic seizures (HP:0002069)2.61118406
64Urinary urgency (HP:0000012)2.60103738
65Urinary bladder sphincter dysfunction (HP:0002839)2.59167649
66Hemiplegia (HP:0002301)2.59032927
67Myositis (HP:0100614)2.54566338
68Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.54440107
69Hyperventilation (HP:0002883)2.54018340
70Pulmonary embolism (HP:0002204)2.53829338
71Elevated erythrocyte sedimentation rate (HP:0003565)2.53567817
72Dysmetria (HP:0001310)2.51004992
73Gingivitis (HP:0000230)2.43662192
74Abnormality of cells of the lymphoid lineage (HP:0012140)2.43206645
75Inflammation of the large intestine (HP:0002037)2.42285829
76IgM deficiency (HP:0002850)2.41687447
77Supranuclear gaze palsy (HP:0000605)2.39934424
78Arterial thrombosis (HP:0004420)2.39300365
79Abnormality of T cell physiology (HP:0011840)2.37329583
80Vertigo (HP:0002321)2.35091532
81Granulocytopenia (HP:0001913)2.34200450
82Poor eye contact (HP:0000817)2.33848270
83Urticaria (HP:0001025)2.31920690
84Cellulitis (HP:0100658)2.31335539
85Optic neuritis (HP:0100653)2.31196355
86Retrobulbar optic neuritis (HP:0100654)2.31196355
87Scanning speech (HP:0002168)2.29214320
88Stomach cancer (HP:0012126)2.25509046
89Spinal canal stenosis (HP:0003416)2.25505230
90Gastrointestinal inflammation (HP:0004386)2.25094241
91Action tremor (HP:0002345)2.21364259
92Episodic fever (HP:0001954)2.20006538
93Mediastinal lymphadenopathy (HP:0100721)2.18949204
94Stereotypic behavior (HP:0000733)2.18295339
95Meningitis (HP:0001287)2.16938754
96Abnormal social behavior (HP:0012433)2.15811139
97Impaired social interactions (HP:0000735)2.15811139
98Papilloma (HP:0012740)2.15537505
99Verrucae (HP:0200043)2.15537505
100Generalized hypopigmentation of hair (HP:0011358)2.12201407
101Abnormality of eosinophils (HP:0001879)2.11604194
102Chronic sinusitis (HP:0011109)2.11472350
103Impaired vibratory sensation (HP:0002495)2.10754328
104Hypochromic anemia (HP:0001931)2.10540922
105Dyskinesia (HP:0100660)2.08467816
106Memory impairment (HP:0002354)2.07319740
107Anorexia (HP:0002039)2.06099988
108Pustule (HP:0200039)2.05818098
109Hypochromic microcytic anemia (HP:0004840)2.05692879
110Abnormality of the nasal mucosa (HP:0000433)2.04818209
111Ankle clonus (HP:0011448)2.04676761
112Spastic gait (HP:0002064)2.04318427
113Colitis (HP:0002583)2.04266597
114Gangrene (HP:0100758)2.02594722
115Petechiae (HP:0000967)2.02262906
116Agammaglobulinemia (HP:0004432)2.01000386
117Abnormal eating behavior (HP:0100738)2.00952620
118Fair hair (HP:0002286)2.00599102
119Chronic obstructive pulmonary disease (HP:0006510)2.00470384
120Obstructive lung disease (HP:0006536)2.00470384
121Joint swelling (HP:0001386)1.98214358
122Protruding tongue (HP:0010808)1.97744214
123Dysdiadochokinesis (HP:0002075)1.97642930
124Depression (HP:0000716)1.96325793
125Amblyopia (HP:0000646)1.94514818
126Eosinophilia (HP:0001880)1.94103116
127Abnormality of the pleura (HP:0002103)1.92933585
128Deep palmar crease (HP:0006191)1.92681460
129Abnormality of the lower motor neuron (HP:0002366)1.92351030
130Chronic diarrhea (HP:0002028)1.91899958
131Inappropriate behavior (HP:0000719)1.91756731
132Ocular albinism (HP:0001107)1.91701719
133Obstructive sleep apnea (HP:0002870)1.90192852
134Encephalitis (HP:0002383)1.89580443
135Sepsis (HP:0100806)1.89547731
136Lymphopenia (HP:0001888)1.89360014
137Basal cell carcinoma (HP:0002671)1.89072627
138Progressive inability to walk (HP:0002505)1.88089694
139Osteomyelitis (HP:0002754)1.86854977
140Hypoplasia of the thymus (HP:0000778)1.86802076
141Gastrointestinal stroma tumor (HP:0100723)1.86717780
142Abnormality of saccadic eye movements (HP:0000570)1.85829063
143Absent speech (HP:0001344)1.83112591
144Pulmonary infiltrates (HP:0002113)1.82166417
145Increased IgE level (HP:0003212)1.82002033
146Recurrent abscess formation (HP:0002722)1.81072546
147Excessive salivation (HP:0003781)1.80949920
148Drooling (HP:0002307)1.80949920
149Autoimmune hemolytic anemia (HP:0001890)1.80465179

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK4.18539390
2MAP4K13.54665172
3MAP3K42.60505701
4MAP3K92.53733621
5CDK192.51822642
6MAP3K132.46205160
7MAP2K72.38989238
8MAP3K122.36302979
9RIPK42.34861095
10EPHA42.31602880
11NTRK32.28668249
12ITK2.27591171
13DAPK22.19512263
14TAOK32.05735655
15BLK2.03756967
16JAK31.82074874
17GRK61.80609809
18SIK21.80284783
19PRPF4B1.78374651
20ZAP701.73681671
21PRKCH1.66995959
22PAK61.65213983
23TAOK11.64792504
24NTRK21.64693850
25DAPK11.64529987
26FES1.62786380
27TYRO31.55757054
28MAP2K41.50493498
29IRAK41.49003480
30FGFR31.47566199
31SIK31.46848014
32CASK1.42895620
33JAK11.42793845
34CAMKK21.34725476
35KSR21.33953810
36IKBKE1.28739489
37FGFR41.24715200
38RAF11.23878710
39CAMKK11.23498393
40EEF2K1.22421665
41LYN1.19583282
42SYK1.17557593
43TYK21.16330858
44STK101.16019223
45MAP2K31.14559182
46PDK11.13524149
47SGK31.09255074
48MAP3K71.08639158
49LCK1.08558553
50BMPR21.07787381
51MARK21.06903616
52TNK21.05917032
53SGK21.04518171
54STK381.02070949
55HCK1.00974037
56CCNB11.00331582
57MINK10.99306601
58STK110.98340967
59UHMK10.98178110
60TBK10.97863914
61PRKCQ0.96623125
62KSR10.95606358
63MAP3K140.94795899
64TEC0.91434496
65CSF1R0.90948808
66CDK50.89132237
67IKBKB0.88765889
68PLK20.86207972
69ALK0.84843225
70RET0.84497484
71MAP3K110.84152819
72MAP3K60.81604725
73CSK0.80752343
74JAK20.79069441
75NEK60.76781010
76WNK10.75879804
77CAMK10.75038769
78MAPK130.74366956
79TNIK0.70801102
80TSSK60.68717636
81IRAK20.67856816
82PIK3CG0.67115523
83YES10.66029082
84OXSR10.65352720
85FGR0.61291884
86PIM10.61100951
87CAMK40.60756044
88SGK2230.60603175
89SGK4940.60603175
90MAP3K20.59886487
91MAPK70.56109327
92BTK0.55906998
93PRKD20.55747959
94PTK2B0.55457714
95TESK20.55013918
96SGK10.54995534
97PAK30.54976832
98PRKD30.54508708
99NLK0.53508535
100MAP2K60.53032004
101EPHB10.52928933
102MARK30.52145844
103DMPK0.51559228
104GRK50.51191213
105PDPK10.50651955
106PRKCG0.48511646
107FYN0.46638981
108PASK0.45148573
109MAPK120.43327228
110IRAK10.42339297
111MAP3K10.40110023
112FGFR20.38785873
113CDK180.38052443
114ERN10.37946072
115FRK0.37680647
116MAPK110.37385639
117MELK0.36613098
118GRK70.34796726
119CDK150.34688758
120CAMK2A0.34673133
121DYRK1A0.32288773
122CLK10.30792905
123CDK11A0.29762738
124CAMK2B0.29068588
125PDGFRB0.28886051
126HIPK20.28829115
127KIT0.28775617

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.72838248
2T cell receptor signaling pathway_Homo sapiens_hsa046602.51393482
3Nicotine addiction_Homo sapiens_hsa050332.50431193
4Long-term potentiation_Homo sapiens_hsa047202.32523827
5Synaptic vesicle cycle_Homo sapiens_hsa047212.20344292
6Olfactory transduction_Homo sapiens_hsa047402.08739857
7Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.02717856
8Morphine addiction_Homo sapiens_hsa050321.91730555
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.90557455
10Glutamatergic synapse_Homo sapiens_hsa047241.85189168
11Amphetamine addiction_Homo sapiens_hsa050311.83395592
12Circadian entrainment_Homo sapiens_hsa047131.83005406
13Salivary secretion_Homo sapiens_hsa049701.70469217
14Phosphatidylinositol signaling system_Homo sapiens_hsa040701.63128849
15Gastric acid secretion_Homo sapiens_hsa049711.54659456
16Aldosterone synthesis and secretion_Homo sapiens_hsa049251.48543199
17Staphylococcus aureus infection_Homo sapiens_hsa051501.47850633
18Dopaminergic synapse_Homo sapiens_hsa047281.47629941
19GABAergic synapse_Homo sapiens_hsa047271.42189224
20Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.40445619
21Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.37854810
22Insulin secretion_Homo sapiens_hsa049111.35774582
23Long-term depression_Homo sapiens_hsa047301.34886768
24Cholinergic synapse_Homo sapiens_hsa047251.34688152
25Oxytocin signaling pathway_Homo sapiens_hsa049211.34209602
26Renin secretion_Homo sapiens_hsa049241.33245383
27Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.30430412
28Osteoclast differentiation_Homo sapiens_hsa043801.29464878
29Chemokine signaling pathway_Homo sapiens_hsa040621.29255510
30Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.24088269
31Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.21566623
32Asthma_Homo sapiens_hsa053101.19708321
33GnRH signaling pathway_Homo sapiens_hsa049121.16140459
34B cell receptor signaling pathway_Homo sapiens_hsa046621.14966064
35Type I diabetes mellitus_Homo sapiens_hsa049401.14481486
36Calcium signaling pathway_Homo sapiens_hsa040201.11580850
37Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.11165368
38cAMP signaling pathway_Homo sapiens_hsa040241.10343682
39Taste transduction_Homo sapiens_hsa047421.09587176
40Intestinal immune network for IgA production_Homo sapiens_hsa046721.06899451
41Influenza A_Homo sapiens_hsa051641.05946311
42ErbB signaling pathway_Homo sapiens_hsa040121.05777725
43Type II diabetes mellitus_Homo sapiens_hsa049301.05776045
44VEGF signaling pathway_Homo sapiens_hsa043701.05724632
45Viral myocarditis_Homo sapiens_hsa054161.04920565
46Measles_Homo sapiens_hsa051621.04768998
47Graft-versus-host disease_Homo sapiens_hsa053321.04630025
48Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.04517332
49Allograft rejection_Homo sapiens_hsa053301.02868066
50Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.01141942
51Estrogen signaling pathway_Homo sapiens_hsa049150.98929075
52MAPK signaling pathway_Homo sapiens_hsa040100.98915645
53Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.96357948
54Prolactin signaling pathway_Homo sapiens_hsa049170.95712382
55Neurotrophin signaling pathway_Homo sapiens_hsa047220.95301193
56NF-kappa B signaling pathway_Homo sapiens_hsa040640.93097688
57Inositol phosphate metabolism_Homo sapiens_hsa005620.92413908
58Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.92288708
59Leishmaniasis_Homo sapiens_hsa051400.92188333
60Glioma_Homo sapiens_hsa052140.92089072
61Cocaine addiction_Homo sapiens_hsa050300.91209898
62Serotonergic synapse_Homo sapiens_hsa047260.90956335
63Collecting duct acid secretion_Homo sapiens_hsa049660.90884624
64Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.90542887
65cGMP-PKG signaling pathway_Homo sapiens_hsa040220.89922930
66Malaria_Homo sapiens_hsa051440.87690437
67Pancreatic cancer_Homo sapiens_hsa052120.86012963
68Choline metabolism in cancer_Homo sapiens_hsa052310.84676726
69Colorectal cancer_Homo sapiens_hsa052100.83843962
70Platelet activation_Homo sapiens_hsa046110.82516870
71Herpes simplex infection_Homo sapiens_hsa051680.81965544
72Hematopoietic cell lineage_Homo sapiens_hsa046400.81699851
73Dorso-ventral axis formation_Homo sapiens_hsa043200.81691446
74Non-small cell lung cancer_Homo sapiens_hsa052230.80998659
75Hepatitis B_Homo sapiens_hsa051610.78902255
76Phospholipase D signaling pathway_Homo sapiens_hsa040720.77445381
77African trypanosomiasis_Homo sapiens_hsa051430.76478830
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.75922990
79Hepatitis C_Homo sapiens_hsa051600.74038076
80Jak-STAT signaling pathway_Homo sapiens_hsa046300.73904958
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.72840707
82Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.72674904
83Autoimmune thyroid disease_Homo sapiens_hsa053200.72253033
84mTOR signaling pathway_Homo sapiens_hsa041500.72111032
85Legionellosis_Homo sapiens_hsa051340.70813188
86Acute myeloid leukemia_Homo sapiens_hsa052210.70372116
87Shigellosis_Homo sapiens_hsa051310.68798579
88Tuberculosis_Homo sapiens_hsa051520.68153218
89Vascular smooth muscle contraction_Homo sapiens_hsa042700.67891519
90Gap junction_Homo sapiens_hsa045400.67735678
91TNF signaling pathway_Homo sapiens_hsa046680.66862343
92RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.66484912
93Apoptosis_Homo sapiens_hsa042100.66482133
94Thyroid hormone signaling pathway_Homo sapiens_hsa049190.66012384
95NOD-like receptor signaling pathway_Homo sapiens_hsa046210.65173520
96Rap1 signaling pathway_Homo sapiens_hsa040150.65057221
97FoxO signaling pathway_Homo sapiens_hsa040680.64807512
98Leukocyte transendothelial migration_Homo sapiens_hsa046700.63487929
99Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63038086
100Phagosome_Homo sapiens_hsa041450.62725986
101Circadian rhythm_Homo sapiens_hsa047100.62228762
102Antigen processing and presentation_Homo sapiens_hsa046120.61412369
103Rheumatoid arthritis_Homo sapiens_hsa053230.61182991
104Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.60857375
105Ras signaling pathway_Homo sapiens_hsa040140.60720536
106Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.60518984
107Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.60184001
108Toll-like receptor signaling pathway_Homo sapiens_hsa046200.59769861
109Renal cell carcinoma_Homo sapiens_hsa052110.58921401
110Pancreatic secretion_Homo sapiens_hsa049720.58811798
111Toxoplasmosis_Homo sapiens_hsa051450.58370077
112Endocytosis_Homo sapiens_hsa041440.58063432
113Endometrial cancer_Homo sapiens_hsa052130.57153248
114Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.56879426
115Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.56489326
116AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.55821620

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