IPO13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the importin-beta family of nuclear transport proteins. The encoded protein mediates the import of specific cargo proteins from the cytoplasm to the nucleus and is dependent on the Ras-related nuclear protein-GTPase system. The encoded protein is also involved in nuclear export of the eukaryotic translation initiation factor 1A. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axon ensheathment in central nervous system (GO:0032291)4.98127442
2central nervous system myelination (GO:0022010)4.98127442
3actin-myosin filament sliding (GO:0033275)4.41385075
4muscle filament sliding (GO:0030049)4.41385075
5creatine metabolic process (GO:0006600)4.35238473
6sarcoplasmic reticulum calcium ion transport (GO:0070296)4.31312934
7plasma membrane repair (GO:0001778)4.26988734
8synaptic vesicle maturation (GO:0016188)4.03587673
9regulation of skeletal muscle contraction (GO:0014819)3.99404179
10positive regulation of synapse maturation (GO:0090129)3.95594054
11neuronal action potential propagation (GO:0019227)3.91891518
12sodium ion export (GO:0071436)3.81659555
13positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.77210045
14membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.69690681
15negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.68428628
16regulation of synapse structural plasticity (GO:0051823)3.68204097
17negative regulation of protein localization to cell surface (GO:2000009)3.63604185
18axon ensheathment (GO:0008366)3.59385521
19ensheathment of neurons (GO:0007272)3.59385521
20myelination (GO:0042552)3.58899006
21regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.57596889
22regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.56512731
23cellular potassium ion homeostasis (GO:0030007)3.53954624
24potassium ion import (GO:0010107)3.52290227
25regulation of short-term neuronal synaptic plasticity (GO:0048172)3.49905137
26actin-mediated cell contraction (GO:0070252)3.48905468
27locomotory exploration behavior (GO:0035641)3.46280213
28negative regulation of potassium ion transmembrane transport (GO:1901380)3.45998788
29skeletal muscle contraction (GO:0003009)3.40674553
30sarcomere organization (GO:0045214)3.36877997
31regulation of cell communication by electrical coupling (GO:0010649)3.33935484
32positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.33159764
33regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.31340095
34NADH metabolic process (GO:0006734)3.29954264
35amino acid import (GO:0043090)3.29723007
36cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.26169320
37response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.21822015
38myofibril assembly (GO:0030239)3.21610418
39establishment of mitochondrion localization (GO:0051654)3.21262371
40negative regulation of cell size (GO:0045792)3.20682130
41membrane depolarization during action potential (GO:0086010)3.17411129
42cytoskeletal anchoring at plasma membrane (GO:0007016)3.16020067
43neuromuscular junction development (GO:0007528)3.12628301
44regulation of calcium ion transmembrane transport (GO:1903169)3.11949413
45regulation of calcium ion transmembrane transporter activity (GO:1901019)3.11949413
46synaptic vesicle exocytosis (GO:0016079)3.11017362
47neurotransmitter secretion (GO:0007269)3.10558851
48cell communication by electrical coupling (GO:0010644)3.08588614
49membrane tubulation (GO:0097320)3.08330854
50positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.07501284
51cerebellar granule cell differentiation (GO:0021707)3.07345982
52L-amino acid import (GO:0043092)3.07337345
53striated muscle contraction (GO:0006941)3.03391571
54regulation of ARF protein signal transduction (GO:0032012)3.02035133
55negative regulation of cytosolic calcium ion concentration (GO:0051481)3.01726019
56positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.00452743
57peptidyl-tyrosine autophosphorylation (GO:0038083)2.99333688
58postsynaptic membrane organization (GO:0001941)2.99110312
59neuronal ion channel clustering (GO:0045161)2.96556618
60skeletal muscle fiber development (GO:0048741)2.95086541
61regulation of synapse maturation (GO:0090128)2.94528552
62cardiac muscle hypertrophy (GO:0003300)2.90846841
63activation of protein kinase A activity (GO:0034199)2.90558602
64regulation of membrane repolarization (GO:0060306)2.89237649
65potassium ion homeostasis (GO:0055075)2.88407517
66regulation of relaxation of muscle (GO:1901077)2.88294966
67glutamate secretion (GO:0014047)2.87575224
68positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.84125905
69gluconeogenesis (GO:0006094)2.83978931
70regulation of NFAT protein import into nucleus (GO:0051532)2.83415532
71layer formation in cerebral cortex (GO:0021819)2.82181245
72positive regulation of potassium ion transport (GO:0043268)2.80915599
73dendritic spine morphogenesis (GO:0060997)2.80905137
74cardiac myofibril assembly (GO:0055003)2.79896323
75striated muscle hypertrophy (GO:0014897)2.76877440
76actin filament-based movement (GO:0030048)2.76602599
77cardiac muscle contraction (GO:0060048)2.74839404
78cardiac muscle hypertrophy in response to stress (GO:0014898)2.74320730
79muscle hypertrophy in response to stress (GO:0003299)2.74320730
80cardiac muscle adaptation (GO:0014887)2.74320730
81regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.74036388
82regulation of synaptic vesicle exocytosis (GO:2000300)2.74004619
83response to inactivity (GO:0014854)2.72628798
84myelin maintenance (GO:0043217)2.71894837
85response to muscle activity (GO:0014850)2.71687785
86regulation of neuronal synaptic plasticity (GO:0048168)2.70716474
87positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.70331922
88cerebellar Purkinje cell layer development (GO:0021680)2.69173459
89astrocyte development (GO:0014002)2.66199213
90retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.66194502
91regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.65563717
92adult walking behavior (GO:0007628)2.65467134
93vocalization behavior (GO:0071625)2.65333336
94regulation of synaptic plasticity (GO:0048167)2.64931938
95positive regulation of potassium ion transmembrane transport (GO:1901381)2.64025233
96dendrite morphogenesis (GO:0048813)2.63575957
97positive regulation of myotube differentiation (GO:0010831)2.63384481
98positive regulation of dendritic spine development (GO:0060999)2.61850247
99neuromuscular synaptic transmission (GO:0007274)2.61447314
100dicarboxylic acid biosynthetic process (GO:0043650)2.61142072
101protein targeting to plasma membrane (GO:0072661)2.61013231
102actomyosin structure organization (GO:0031032)2.60281870
103regulation of dendritic spine morphogenesis (GO:0061001)2.59974323
104skeletal muscle adaptation (GO:0043501)2.59562589
105negative regulation of inclusion body assembly (GO:0090084)2.58416966
106nerve growth factor signaling pathway (GO:0038180)2.58063351
107ionotropic glutamate receptor signaling pathway (GO:0035235)2.57867935
108cell-substrate adherens junction assembly (GO:0007045)2.57376180
109focal adhesion assembly (GO:0048041)2.57376180
110hexose biosynthetic process (GO:0019319)2.56468913
111myotube cell development (GO:0014904)2.55772380
112glycogen catabolic process (GO:0005980)2.55164121
113protein localization to endosome (GO:0036010)2.55096754
114establishment of nucleus localization (GO:0040023)2.53616779
115regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.52689778
116neuromuscular process controlling balance (GO:0050885)2.52633297
117substantia nigra development (GO:0021762)2.52498969
118glycine transport (GO:0015816)2.52050487
119regulation of synaptic vesicle transport (GO:1902803)2.51604267
120regulation of actin filament-based movement (GO:1903115)2.51421607
121regulation of early endosome to late endosome transport (GO:2000641)2.51216282
122striated muscle adaptation (GO:0014888)2.50688023
123synaptic vesicle docking involved in exocytosis (GO:0016081)2.50555031
124regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.50323498
125response to parathyroid hormone (GO:0071107)2.49400878
126muscle contraction (GO:0006936)2.48306589
127regulation of cation channel activity (GO:2001257)2.48182752
128mitochondrion transport along microtubule (GO:0047497)2.48088757
129establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.48088757
130transmission of nerve impulse (GO:0019226)2.48087822
131cell communication involved in cardiac conduction (GO:0086065)2.48029418
132negative regulation of axonogenesis (GO:0050771)2.47183181
133muscle system process (GO:0003012)2.47108185
134myelination in peripheral nervous system (GO:0022011)2.45110402
135peripheral nervous system axon ensheathment (GO:0032292)2.45110402
136regulation of long-term neuronal synaptic plasticity (GO:0048169)2.43268764
137negative regulation of microtubule polymerization (GO:0031115)2.42723320

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.27346343
2DROSHA_22980978_ChIP-Seq_HELA_Human2.79661584
3RARB_27405468_Chip-Seq_BRAIN_Mouse2.60936913
4EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.39578249
5TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.31939525
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.30577472
7MTF2_20144788_ChIP-Seq_MESCs_Mouse2.24910451
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.23798171
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.23798171
10SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.23433867
11SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.21769171
12EZH2_27294783_Chip-Seq_ESCs_Mouse2.17526927
13SUZ12_27294783_Chip-Seq_ESCs_Mouse2.12811845
14MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.11650834
15JARID2_20064375_ChIP-Seq_MESCs_Mouse2.05122171
16RARG_19884340_ChIP-ChIP_MEFs_Mouse2.04464238
17JARID2_20075857_ChIP-Seq_MESCs_Mouse1.98957434
18EZH2_27304074_Chip-Seq_ESCs_Mouse1.87617994
19RNF2_27304074_Chip-Seq_ESCs_Mouse1.87599201
20SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.86567235
21PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.85431227
22ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.78598955
23RACK7_27058665_Chip-Seq_MCF-7_Human1.74519307
24* REST_21632747_ChIP-Seq_MESCs_Mouse1.73999325
25SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.71618090
26SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.70628740
27* REST_18959480_ChIP-ChIP_MESCs_Mouse1.69036295
28TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.65036575
29ZFP281_18757296_ChIP-ChIP_E14_Mouse1.61561321
30* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.60426616
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.59934563
32TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.59710483
33* DNAJC2_21179169_ChIP-ChIP_NT2_Human1.59479475
34AR_21572438_ChIP-Seq_LNCaP_Human1.59130579
35WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.56224121
36UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.55440725
37* KDM2B_26808549_Chip-Seq_K562_Human1.55111143
38ERG_21242973_ChIP-ChIP_JURKAT_Human1.55060618
39EED_16625203_ChIP-ChIP_MESCs_Mouse1.53301025
40EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.53273335
41PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.53224470
42SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.52938669
43TET1_21451524_ChIP-Seq_MESCs_Mouse1.52641614
44* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.49102802
45* SA1_27219007_Chip-Seq_ERYTHROID_Human1.48150426
46EP300_21415370_ChIP-Seq_HL-1_Mouse1.47284550
47GBX2_23144817_ChIP-Seq_PC3_Human1.46897278
48CTCF_27219007_Chip-Seq_ERYTHROID_Human1.46409433
49* ELK3_25401928_ChIP-Seq_HUVEC_Human1.45867139
50KDM2B_26808549_Chip-Seq_SUP-B15_Human1.45276961
51TP63_17297297_ChIP-ChIP_HaCaT_Human1.44974814
52* CTCF_27219007_Chip-Seq_Bcells_Human1.44321751
53SRY_22984422_ChIP-ChIP_TESTIS_Rat1.40066397
54TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.37947927
55WT1_25993318_ChIP-Seq_PODOCYTE_Human1.37124764
56THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.36789903
57KDM2B_26808549_Chip-Seq_DND41_Human1.36720371
58TCF7_22412390_ChIP-Seq_EML_Mouse1.36701967
59NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.35841035
60TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.34960414
61TBX20_22080862_ChIP-Seq_HEART_Mouse1.34389438
62TBX20_22328084_ChIP-Seq_HEART_Mouse1.34389438
63ZNF263_19887448_ChIP-Seq_K562_Human1.34382799
64VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.32531199
65STAT6_21828071_ChIP-Seq_BEAS2B_Human1.32078567
66* LXR_22292898_ChIP-Seq_THP-1_Human1.30024312
67IKZF1_21737484_ChIP-ChIP_HCT116_Human1.27754264
68NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.27094558
69ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.26960161
70ZNF274_21170338_ChIP-Seq_K562_Hela1.26573114
71RING1B_27294783_Chip-Seq_ESCs_Mouse1.24689993
72ESR2_21235772_ChIP-Seq_MCF-7_Human1.21693274
73GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.21682035
74VDR_21846776_ChIP-Seq_THP-1_Human1.20464384
75ESR1_20079471_ChIP-ChIP_T-47D_Human1.20312170
76RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.19764911
77TRIM28_21343339_ChIP-Seq_HEK293_Human1.19354055
78CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.17410776
79CLOCK_20551151_ChIP-Seq_293T_Human1.17238833
80PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.17100622
81TET1_21490601_ChIP-Seq_MESCs_Mouse1.16098601
82CDX2_19796622_ChIP-Seq_MESCs_Mouse1.15549433
83SMC4_20622854_ChIP-Seq_HELA_Human1.15520549
84SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14657360
85CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.14360686
86TP53_20018659_ChIP-ChIP_R1E_Mouse1.11522448
87SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.11120135
88ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.10486781
89ELF1_20517297_ChIP-Seq_JURKAT_Human1.10175117
90SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09491062
91SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.08615538
92GATA1_19941827_ChIP-Seq_MEL_Mouse1.07721005
93* NFIB_24661679_ChIP-Seq_LUNG_Mouse1.07386190
94SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.06898994
95* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.06176405
96TP53_23651856_ChIP-Seq_MEFs_Mouse1.05772983
97RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03376233
98GATA3_20176728_ChIP-ChIP_TSCs_Mouse1.02967598
99BCOR_27268052_Chip-Seq_Bcells_Human1.02024194
100KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.01436259
101GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.01080416
102* MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.01065045
103AR_19668381_ChIP-Seq_PC3_Human1.01048402
104CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.00357617
105P53_22127205_ChIP-Seq_FIBROBLAST_Human1.00337946
106ZFP281_27345836_Chip-Seq_ESCs_Mouse1.00235816
107OCT4_19829295_ChIP-Seq_ESCs_Human0.98539472
108KLF4_19829295_ChIP-Seq_ESCs_Human0.98377977
109CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.98170615
110PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.98018210
111KDM2B_26808549_Chip-Seq_JURKAT_Human0.97330768
112SOX2_21211035_ChIP-Seq_LN229_Gbm0.97308420
113SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.97303876
114PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.97203650
115* TP63_22573176_ChIP-Seq_HFKS_Human0.96791613
116P68_20966046_ChIP-Seq_HELA_Human0.96782024
117TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.96703441
118RING1B_27294783_Chip-Seq_NPCs_Mouse0.96027840
119NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.95178466
120TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.94522898
121* ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.94155310
122* P300_27058665_Chip-Seq_ZR-75-30cells_Human0.91928837
123NR3C1_23031785_ChIP-Seq_PC12_Mouse0.91567831
124CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.90656277
125SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.90335706
126FOXH1_21741376_ChIP-Seq_ESCs_Human0.90329117
127SA1_27219007_Chip-Seq_Bcells_Human0.89866535
128DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.89415422
129CREB1_26743006_Chip-Seq_LNCaP_Human0.89406740
130SMAD4_21741376_ChIP-Seq_HESCs_Human0.87513565
131SMAD4_21741376_ChIP-Seq_ESCs_Human0.87316927
132SMAD3_21741376_ChIP-Seq_ESCs_Human0.86771188
133SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.85890876
134AHR_22903824_ChIP-Seq_MCF-7_Human0.82682438
135ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.82638891
136RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.82081289

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.41779074
2MP0000751_myopathy3.88567369
3MP0004145_abnormal_muscle_electrophysio3.87770800
4MP0000749_muscle_degeneration3.26644935
5MP0005451_abnormal_body_composition3.14433114
6MP0003646_muscle_fatigue3.12321078
7MP0004270_analgesia3.09339563
8MP0000747_muscle_weakness2.86663466
9MP0004036_abnormal_muscle_relaxation2.70734402
10MP0002837_dystrophic_cardiac_calcinosis2.59902116
11MP0003705_abnormal_hypodermis_morpholog2.59015986
12MP0003635_abnormal_synaptic_transmissio2.44425625
13MP0003880_abnormal_central_pattern2.35754609
14MP0000920_abnormal_myelination2.35291392
15MP0003329_amyloid_beta_deposits2.28751785
16MP0004233_abnormal_muscle_weight2.23247238
17MP0004087_abnormal_muscle_fiber2.21780919
18MP0000759_abnormal_skeletal_muscle2.13038291
19MP0002106_abnormal_muscle_physiology2.07687078
20MP0002064_seizures2.01108129
21MP0002269_muscular_atrophy2.00797295
22MP0003879_abnormal_hair_cell1.99562505
23MP0002272_abnormal_nervous_system1.93085165
24MP0004084_abnormal_cardiac_muscle1.92525463
25MP0009046_muscle_twitch1.92220076
26MP0008569_lethality_at_weaning1.86172112
27MP0005410_abnormal_fertilization1.85808660
28MP0005620_abnormal_muscle_contractility1.85583532
29MP0005369_muscle_phenotype1.82134223
30MP0002063_abnormal_learning/memory/cond1.82042894
31MP0004858_abnormal_nervous_system1.80366818
32MP0004130_abnormal_muscle_cell1.80276052
33MP0009745_abnormal_behavioral_response1.78433155
34MP0003950_abnormal_plasma_membrane1.64429602
35MP0001486_abnormal_startle_reflex1.60620642
36MP0004215_abnormal_myocardial_fiber1.58992705
37MP0005423_abnormal_somatic_nervous1.58433919
38MP0003690_abnormal_glial_cell1.55158948
39MP0002734_abnormal_mechanical_nocicepti1.54966813
40MP0005330_cardiomyopathy1.53811547
41MP0002822_catalepsy1.51428237
42MP0003137_abnormal_impulse_conducting1.49784346
43MP0005623_abnormal_meninges_morphology1.46029259
44MP0000750_abnormal_muscle_regeneration1.45485753
45MP0003634_abnormal_glial_cell1.45164138
46MP0008260_abnormal_autophagy1.44666786
47MP0004885_abnormal_endolymph1.43124424
48MP0000733_abnormal_muscle_development1.37386153
49MP0005670_abnormal_white_adipose1.37039310
50MP0002572_abnormal_emotion/affect_behav1.34512980
51MP0000778_abnormal_nervous_system1.32099684
52MP0001299_abnormal_eye_distance/1.30825518
53MP0000955_abnormal_spinal_cord1.30101735
54MP0004510_myositis1.28415261
55MP0002234_abnormal_pharynx_morphology1.24196269
56MP0002108_abnormal_muscle_morphology1.22753178
57MP0002972_abnormal_cardiac_muscle1.21869445
58MP0001440_abnormal_grooming_behavior1.21531694
59MP0000579_abnormal_nail_morphology1.19577611
60MP0004811_abnormal_neuron_physiology1.18730700
61MP0005058_abnormal_lysosome_morphology1.17425047
62MP0002067_abnormal_sensory_capabilities1.16756030
63MP0002066_abnormal_motor_capabilities/c1.16389895
64MP0002882_abnormal_neuron_morphology1.15030005
65MP0001849_ear_inflammation1.14019014
66MP0002229_neurodegeneration1.11965352
67MP0005409_darkened_coat_color1.10828478
68MP0003632_abnormal_nervous_system1.09320727
69MP0001529_abnormal_vocalization1.08268607
70MP0009840_abnormal_foam_cell1.07524414
71MP0001968_abnormal_touch/_nociception1.06642379
72MP0004085_abnormal_heartbeat1.05707464
73MP0001984_abnormal_olfaction1.05614626
74MP0004924_abnormal_behavior1.05436818
75MP0005386_behavior/neurological_phenoty1.05436818
76MP0003631_nervous_system_phenotype1.04442465
77MP0003633_abnormal_nervous_system1.04226072
78MP0004185_abnormal_adipocyte_glucose1.02649122
79MP0004142_abnormal_muscle_tone1.01683648
80MP0002184_abnormal_innervation1.01182991
81MP0001348_abnormal_lacrimal_gland1.00869217
82MP0004484_altered_response_of1.00642400
83MP0003172_abnormal_lysosome_physiology0.99885487
84MP0010630_abnormal_cardiac_muscle0.98161627
85MP0001502_abnormal_circadian_rhythm0.97777106
86MP0000604_amyloidosis0.97301549
87MP0002090_abnormal_vision0.97184269
88MP0001970_abnormal_pain_threshold0.96828844
89MP0000013_abnormal_adipose_tissue0.96548409
90MP0009780_abnormal_chondrocyte_physiolo0.94263564
91MP0004043_abnormal_pH_regulation0.94061271
92MP0004742_abnormal_vestibular_system0.92859621
93MP0002249_abnormal_larynx_morphology0.92676753
94MP0008961_abnormal_basal_metabolism0.92611391
95MP0002653_abnormal_ependyma_morphology0.90903929
96MP0002733_abnormal_thermal_nociception0.89519079
97MP0008775_abnormal_heart_ventricle0.89046342
98MP0008874_decreased_physiological_sensi0.86735025
99MP0000003_abnormal_adipose_tissue0.85312032
100MP0002735_abnormal_chemical_nociception0.85112990
101MP0005375_adipose_tissue_phenotype0.84798177
102MP0001905_abnormal_dopamine_level0.84745058
103MP0008438_abnormal_cutaneous_collagen0.84500169
104MP0002152_abnormal_brain_morphology0.84451211
105MP0002736_abnormal_nociception_after0.83462040
106MP0004134_abnormal_chest_morphology0.82991170
107MP0002332_abnormal_exercise_endurance0.82379151
108MP0003075_altered_response_to0.78999611
109MP0002557_abnormal_social/conspecific_i0.78015900
110MP0002909_abnormal_adrenal_gland0.77974253
111MP0003221_abnormal_cardiomyocyte_apopto0.77777816
112MP0002971_abnormal_brown_adipose0.76609455
113MP0005666_abnormal_adipose_tissue0.76240184
114MP0005551_abnormal_eye_electrophysiolog0.75690145
115MP0006138_congestive_heart_failure0.75268587
116MP0001958_emphysema0.75172786
117MP0005385_cardiovascular_system_phenoty0.72227925
118MP0001544_abnormal_cardiovascular_syste0.72227925
119MP0001346_abnormal_lacrimal_gland0.69514195
120MP0002089_abnormal_postnatal_growth/wei0.68359831
121MP0000678_abnormal_parathyroid_gland0.67103901
122MP0006036_abnormal_mitochondrial_physio0.66892191
123MP0003123_paternal_imprinting0.65117774
124MP0003045_fibrosis0.64517045

Predicted human phenotypes

RankGene SetZ-score
1Exercise-induced myalgia (HP:0003738)5.93921830
2Muscle fiber inclusion bodies (HP:0100299)5.53067709
3Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)5.30565038
4Exercise-induced muscle cramps (HP:0003710)5.14871362
5Nemaline bodies (HP:0003798)4.86812939
6Muscle hypertrophy of the lower extremities (HP:0008968)4.78942658
7Difficulty running (HP:0009046)4.58646536
8Type 1 muscle fiber predominance (HP:0003803)4.49195193
9Muscle fiber splitting (HP:0003555)4.45930565
10Hyporeflexia of lower limbs (HP:0002600)4.42752567
11Calf muscle hypertrophy (HP:0008981)4.41220323
12Distal arthrogryposis (HP:0005684)3.89394393
13Round ear (HP:0100830)3.82564825
14EMG: myopathic abnormalities (HP:0003458)3.65337285
15Myopathic facies (HP:0002058)3.62047103
16Abnormality of the calf musculature (HP:0001430)3.40323933
17Distal lower limb muscle weakness (HP:0009053)3.37664515
18Myoglobinuria (HP:0002913)3.31195887
19Myokymia (HP:0002411)3.27766502
20Neurofibrillary tangles (HP:0002185)3.26807107
21Increased variability in muscle fiber diameter (HP:0003557)3.19749904
22Sudden death (HP:0001699)3.14108237
23Supranuclear gaze palsy (HP:0000605)3.12118340
24Muscle stiffness (HP:0003552)3.08952494
25Abnormality of skeletal muscle fiber size (HP:0012084)3.05612670
26Myotonia (HP:0002486)3.01155253
27Ankle clonus (HP:0011448)2.96856125
28Calcaneovalgus deformity (HP:0001848)2.93147668
29Increased connective tissue (HP:0009025)2.93029799
30Cerebral inclusion bodies (HP:0100314)2.87575912
31Difficulty climbing stairs (HP:0003551)2.70686384
32Deformed tarsal bones (HP:0008119)2.70287461
33Ulnar deviation of the wrist (HP:0003049)2.62762901
34Centrally nucleated skeletal muscle fibers (HP:0003687)2.60728838
35Obstructive sleep apnea (HP:0002870)2.56494325
36Neck muscle weakness (HP:0000467)2.52839891
37Spastic gait (HP:0002064)2.51294513
38Focal motor seizures (HP:0011153)2.47231528
39Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.46880670
40Degeneration of the lateral corticospinal tracts (HP:0002314)2.46880670
41Scapular winging (HP:0003691)2.44072667
42Bundle branch block (HP:0011710)2.38241528
43Abnormality of the left ventricular outflow tract (HP:0011103)2.37905652
44Subaortic stenosis (HP:0001682)2.37905652
45Urinary urgency (HP:0000012)2.37689226
46Lower limb amyotrophy (HP:0007210)2.36624347
47Spinal rigidity (HP:0003306)2.36448317
48Visual hallucinations (HP:0002367)2.33332067
49Action tremor (HP:0002345)2.30943100
50Insomnia (HP:0100785)2.30501030
51Gowers sign (HP:0003391)2.30295943
52Dysmetria (HP:0001310)2.29910124
53Intention tremor (HP:0002080)2.29311598
54Achilles tendon contracture (HP:0001771)2.27407752
55Focal seizures (HP:0007359)2.26595923
56Rapidly progressive (HP:0003678)2.26399823
57Bulbar palsy (HP:0001283)2.25949061
58Abnormality of the corticospinal tract (HP:0002492)2.24080722
59Rhabdomyolysis (HP:0003201)2.22549522
60Abnormal atrioventricular conduction (HP:0005150)2.22403805
61Asymmetric septal hypertrophy (HP:0001670)2.21659423
62Lower limb muscle weakness (HP:0007340)2.21586205
63Frequent falls (HP:0002359)2.19282583
64Foot dorsiflexor weakness (HP:0009027)2.18393335
65Heart block (HP:0012722)2.17673803
66Megalencephaly (HP:0001355)2.14475880
67Upper limb amyotrophy (HP:0009129)2.11828742
68Distal upper limb amyotrophy (HP:0007149)2.11828742
69Bowel incontinence (HP:0002607)2.11414355
70Abnormality of the foot musculature (HP:0001436)2.10923404
71Onion bulb formation (HP:0003383)2.10257110
72Postural instability (HP:0002172)2.09652186
73Central scotoma (HP:0000603)2.08170191
74Cerebral hypomyelination (HP:0006808)2.06188446
75Insidious onset (HP:0003587)2.05018137
76Termporal pattern (HP:0011008)2.05018137
77Broad metatarsal (HP:0001783)2.04253693
78Peripheral hypomyelination (HP:0007182)2.03274162
79Hyperacusis (HP:0010780)2.02193493
80Shoulder girdle muscle weakness (HP:0003547)2.02139470
81Slender build (HP:0001533)2.01587762
82Diplopia (HP:0000651)2.01325038
83Abnormality of binocular vision (HP:0011514)2.01325038
84Prolonged QT interval (HP:0001657)2.01038356
85Limb-girdle muscle weakness (HP:0003325)2.00677603
86Rimmed vacuoles (HP:0003805)2.00082583
87Neuronal loss in central nervous system (HP:0002529)1.99951986
88Abnormal large intestine physiology (HP:0012700)1.97520481
89Rigidity (HP:0002063)1.96966931
90Dysdiadochokinesis (HP:0002075)1.95989800
91Atrial fibrillation (HP:0005110)1.95555780
92Limb-girdle muscle atrophy (HP:0003797)1.95297380
93Abnormality of the musculature of the pelvis (HP:0001469)1.95120054
94Abnormality of the hip-girdle musculature (HP:0001445)1.95120054
95Dysmetric saccades (HP:0000641)1.94866179
96Impaired vibration sensation in the lower limbs (HP:0002166)1.94588310
97Absent phalangeal crease (HP:0006109)1.94462006
98Pheochromocytoma (HP:0002666)1.94271459
99Urinary bladder sphincter dysfunction (HP:0002839)1.94254142
100Distal lower limb amyotrophy (HP:0008944)1.92564731
101Scanning speech (HP:0002168)1.91673351
102Abnormality of the Achilles tendon (HP:0005109)1.90692692
103Muscular dystrophy (HP:0003560)1.90566718
104Truncal ataxia (HP:0002078)1.89923088
105Mildly elevated creatine phosphokinase (HP:0008180)1.88969934
106Poor eye contact (HP:0000817)1.88824535
107EMG: neuropathic changes (HP:0003445)1.88223020
108Clonus (HP:0002169)1.88051470
109Ragged-red muscle fibers (HP:0003200)1.87698969
110Depression (HP:0000716)1.86832270
111Abnormal gallbladder physiology (HP:0012438)1.85894404
112Cholecystitis (HP:0001082)1.85894404
113Fetal akinesia sequence (HP:0001989)1.85651869
114Abnormality of the shoulder girdle musculature (HP:0001435)1.85002213
115Ventricular tachycardia (HP:0004756)1.84761760
116Primary atrial arrhythmia (HP:0001692)1.83484973
117Stridor (HP:0010307)1.83468755
118Epileptic encephalopathy (HP:0200134)1.82453760
119Slow progression (HP:0003677)1.81784900
120Atrioventricular block (HP:0001678)1.81247333
121Proximal amyotrophy (HP:0007126)1.80725335
122Ventricular fibrillation (HP:0001663)1.79749886
123Bell-shaped thorax (HP:0001591)1.79663399
124Hand muscle atrophy (HP:0009130)1.79549306
125Back pain (HP:0003418)1.77219874
126Tetraplegia (HP:0002445)1.76306248
127Dilated cardiomyopathy (HP:0001644)1.75515231
128Hammertoe (HP:0001765)1.74795977
129Axonal loss (HP:0003447)1.73687514
130Ventricular arrhythmia (HP:0004308)1.72146736
131Generalized muscle weakness (HP:0003324)1.71184764

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN3.53680618
2OBSCN3.25460071
3PHKG13.24242885
4PHKG23.24242885
5STK392.77231168
6ICK2.49654627
7PAK62.41176490
8TRIB32.37836679
9PRKD32.37008081
10EPHB12.16182772
11MAP3K92.10090744
12EPHA41.89403338
13DMPK1.84638978
14OXSR11.80621055
15KSR21.66949057
16PRPF4B1.65459796
17PDK41.57096014
18PDK31.57096014
19MARK11.55061255
20PINK11.53075437
21NTRK11.45851199
22CDK191.42901353
23WNK11.42571440
24TYRO31.40868235
25SIK21.40052130
26NTRK31.37201489
27NTRK21.35745616
28PNCK1.32740067
29MAP3K71.32319617
30MINK11.29606542
31WNK41.28817110
32SIK11.26402517
33NME11.24184061
34CAMKK11.21881952
35MAP3K111.18004963
36UHMK11.16163621
37NEK11.14193750
38PKN11.12693850
39DAPK21.12368841
40ROCK21.10647121
41MAP3K41.10340020
42EEF2K1.10164225
43LIMK11.09350457
44FGFR21.08253724
45CDK51.08206231
46CAMK1G1.08155052
47LMTK21.01715084
48MAP2K41.01335804
49SMG10.99162707
50PTK2B0.96361868
51MAPKAPK50.96323376
52PAK30.93776694
53ARAF0.92709993
54MARK20.92388864
55BRAF0.89510307
56RIPK10.88556194
57TAOK10.88429206
58SGK30.87447418
59TNIK0.86948634
60CDK150.85197596
61TAOK20.84692892
62PDK20.84617000
63DYRK1B0.83667642
64ERN10.82939433
65CAMK2D0.82881698
66CAMK10.81802326
67CDK140.81623396
68CDK180.81222578
69SGK2230.80998013
70SGK4940.80998013
71PDPK10.80746520
72BCR0.79585507
73RAF10.79288951
74MAP2K30.79220141
75KSR10.76582337
76PRKD10.76396655
77MOS0.75939072
78MAP3K30.75521178
79TESK10.74268604
80IRAK30.73831974
81RPS6KA20.73829522
82MAPK120.72879440
83CDK11A0.72572093
84CAMK2B0.71879488
85CDK120.71368043
86MTOR0.71139410
87MUSK0.70497182
88PRKD20.68446072
89MAPK100.67815110
90STK380.67533680
91CAMK2G0.66629435
92PRKCH0.64128215
93MAP3K130.63888287
94DDR20.63406006
95MET0.62290810
96AKT20.61117789
97STK110.60149560
98CAMKK20.60093263
99PDK10.59362517
100RET0.59307433
101PDGFRA0.59060824
102ROCK10.57641288
103PIM20.56725036
104ILK0.56531819
105ALK0.56426159
106CAMK2A0.56348387
107CCNB10.55808186
108CLK10.54871076
109BMX0.53731226
110NEK60.53729063
111DAPK30.53606356
112PRKAA10.53595183
113LATS20.53497841
114SGK20.51828703
115PIK3CG0.51756499
116CAMK40.50822316
117PTK20.48353768
118MAP2K10.47482203
119PKN20.46458702
120TESK20.45872287
121MAPK40.45827263
122TRPM70.45138472
123SGK10.44596836
124MAPKAPK30.42763736
125MAP2K60.42537279
126IRAK20.42214775
127FYN0.41832150
128CDC42BPA0.41461270
129FGR0.41354617
130PRKCG0.41056295
131PRKACB0.39511514
132RPS6KB10.39448395
133RPS6KA30.38804526
134MAP3K10.38584425
135MAPK110.37304774
136PRKG20.36656134

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.42528053
2Cardiac muscle contraction_Homo sapiens_hsa042602.17524414
3Dilated cardiomyopathy_Homo sapiens_hsa054142.14198958
4Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042612.08509162
5Olfactory transduction_Homo sapiens_hsa047402.08158678
6Circadian entrainment_Homo sapiens_hsa047132.00836374
7Synaptic vesicle cycle_Homo sapiens_hsa047211.98041984
8Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.97929389
9GABAergic synapse_Homo sapiens_hsa047271.93483780
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.86179138
11Glutamatergic synapse_Homo sapiens_hsa047241.85368783
12Oxytocin signaling pathway_Homo sapiens_hsa049211.77609649
13Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.75704109
14Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.74641447
15Gastric acid secretion_Homo sapiens_hsa049711.72975087
16Morphine addiction_Homo sapiens_hsa050321.70403343
17Long-term potentiation_Homo sapiens_hsa047201.69561528
18Nicotine addiction_Homo sapiens_hsa050331.64270962
19Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.57575731
20Salivary secretion_Homo sapiens_hsa049701.55657064
21Arginine biosynthesis_Homo sapiens_hsa002201.55372438
22Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.53392120
23Dopaminergic synapse_Homo sapiens_hsa047281.49790247
24Cholinergic synapse_Homo sapiens_hsa047251.45589683
25Arginine and proline metabolism_Homo sapiens_hsa003301.43154145
26Calcium signaling pathway_Homo sapiens_hsa040201.40006743
27Axon guidance_Homo sapiens_hsa043601.37756346
282-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.36085423
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.35101528
30Insulin secretion_Homo sapiens_hsa049111.34209411
31Renin secretion_Homo sapiens_hsa049241.33686949
32Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.33256015
33Prion diseases_Homo sapiens_hsa050201.32554649
34Amphetamine addiction_Homo sapiens_hsa050311.30342763
35Long-term depression_Homo sapiens_hsa047301.29804604
36GnRH signaling pathway_Homo sapiens_hsa049121.26748426
37cGMP-PKG signaling pathway_Homo sapiens_hsa040221.24359513
38Aldosterone synthesis and secretion_Homo sapiens_hsa049251.22004651
39Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.18061862
40Gap junction_Homo sapiens_hsa045401.17755871
41Renal cell carcinoma_Homo sapiens_hsa052111.11230882
42Pentose phosphate pathway_Homo sapiens_hsa000301.10127853
43Vascular smooth muscle contraction_Homo sapiens_hsa042701.09532001
44Tight junction_Homo sapiens_hsa045301.08536038
45cAMP signaling pathway_Homo sapiens_hsa040241.03471700
46Serotonergic synapse_Homo sapiens_hsa047261.02864635
47Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.01906390
48Dorso-ventral axis formation_Homo sapiens_hsa043201.01193093
49Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.00870289
50Sulfur relay system_Homo sapiens_hsa041221.00627307
51VEGF signaling pathway_Homo sapiens_hsa043700.99064116
52Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.98654836
53Fructose and mannose metabolism_Homo sapiens_hsa000510.97602069
54Phospholipase D signaling pathway_Homo sapiens_hsa040720.96984250
55Cocaine addiction_Homo sapiens_hsa050300.95709301
56Nitrogen metabolism_Homo sapiens_hsa009100.95585814
57Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.94058087
58Glioma_Homo sapiens_hsa052140.93971396
59ErbB signaling pathway_Homo sapiens_hsa040120.92174189
60Glucagon signaling pathway_Homo sapiens_hsa049220.92141480
61Endocytosis_Homo sapiens_hsa041440.91881588
62Estrogen signaling pathway_Homo sapiens_hsa049150.91395937
63Type II diabetes mellitus_Homo sapiens_hsa049300.90838130
64Phenylalanine metabolism_Homo sapiens_hsa003600.89707088
65Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.88314856
66Vitamin B6 metabolism_Homo sapiens_hsa007500.87520481
67Fatty acid biosynthesis_Homo sapiens_hsa000610.87344538
68Circadian rhythm_Homo sapiens_hsa047100.86054761
69Phosphatidylinositol signaling system_Homo sapiens_hsa040700.85154636
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.84487204
71Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.83555528
72MAPK signaling pathway_Homo sapiens_hsa040100.83534074
73Fatty acid elongation_Homo sapiens_hsa000620.79640122
74Adipocytokine signaling pathway_Homo sapiens_hsa049200.78729226
75Insulin signaling pathway_Homo sapiens_hsa049100.77405576
76Sphingolipid signaling pathway_Homo sapiens_hsa040710.77391537
77Neurotrophin signaling pathway_Homo sapiens_hsa047220.73915934
78Taste transduction_Homo sapiens_hsa047420.72908545
79Bile secretion_Homo sapiens_hsa049760.71762877
80Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71601957
81Focal adhesion_Homo sapiens_hsa045100.70459951
82Collecting duct acid secretion_Homo sapiens_hsa049660.70383777
83Pancreatic secretion_Homo sapiens_hsa049720.69928247
84Endometrial cancer_Homo sapiens_hsa052130.69725053
85Melanogenesis_Homo sapiens_hsa049160.68979937
86AMPK signaling pathway_Homo sapiens_hsa041520.68749569
87Non-small cell lung cancer_Homo sapiens_hsa052230.68412371
88Propanoate metabolism_Homo sapiens_hsa006400.67783840
89Ether lipid metabolism_Homo sapiens_hsa005650.67709908
90Galactose metabolism_Homo sapiens_hsa000520.67281411
91Other glycan degradation_Homo sapiens_hsa005110.67007267
92Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.66986987
93Fatty acid metabolism_Homo sapiens_hsa012120.66089022
94Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.65975937
95Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.64396127
96Oocyte meiosis_Homo sapiens_hsa041140.63621036
97Carbon metabolism_Homo sapiens_hsa012000.63181750
98Chronic myeloid leukemia_Homo sapiens_hsa052200.62159118
99Central carbon metabolism in cancer_Homo sapiens_hsa052300.60534840
100Thyroid hormone signaling pathway_Homo sapiens_hsa049190.59742010
101mTOR signaling pathway_Homo sapiens_hsa041500.57911570
102Choline metabolism in cancer_Homo sapiens_hsa052310.57226473
103Alzheimers disease_Homo sapiens_hsa050100.56093125
104Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.55608787
105Insulin resistance_Homo sapiens_hsa049310.55568111
106Ras signaling pathway_Homo sapiens_hsa040140.54606946
107Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54526816
108Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54191629
109Acute myeloid leukemia_Homo sapiens_hsa052210.53508414
110Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.53055890
111Vibrio cholerae infection_Homo sapiens_hsa051100.52263803
112Longevity regulating pathway - mammal_Homo sapiens_hsa042110.51989427
113Rap1 signaling pathway_Homo sapiens_hsa040150.51582144
114Proteoglycans in cancer_Homo sapiens_hsa052050.50769134
115Biosynthesis of amino acids_Homo sapiens_hsa012300.50735691
116Steroid biosynthesis_Homo sapiens_hsa001000.50500076
117Thyroid hormone synthesis_Homo sapiens_hsa049180.48173404
118beta-Alanine metabolism_Homo sapiens_hsa004100.47737743
119Inositol phosphate metabolism_Homo sapiens_hsa005620.46198507
120HIF-1 signaling pathway_Homo sapiens_hsa040660.45646584
121Bladder cancer_Homo sapiens_hsa052190.45035874
122Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.44970908

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