IQCB2P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cytidine metabolic process (GO:0046087)8.02242313
2cytidine catabolic process (GO:0006216)8.02242313
3cytidine deamination (GO:0009972)8.02242313
4regulation of regulatory T cell differentiation (GO:0045589)7.03338220
5pyrimidine ribonucleoside catabolic process (GO:0046133)6.87759251
6positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)6.62883243
7regulation of hypersensitivity (GO:0002883)6.59865205
8negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)6.22117642
9regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)5.98369885
10DNA deamination (GO:0045006)5.45823531
11regulation of meiosis I (GO:0060631)5.41251222
12positive regulation of inflammatory response to antigenic stimulus (GO:0002863)5.28004802
13intestinal epithelial cell development (GO:0060576)5.24593273
14piRNA metabolic process (GO:0034587)5.22219888
15negative regulation of B cell proliferation (GO:0030889)4.99838497
16positive regulation of activated T cell proliferation (GO:0042104)4.97004002
17positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)4.76626744
18regulation of acute inflammatory response to antigenic stimulus (GO:0002864)4.71293199
19regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.69913637
20positive regulation of interleukin-8 secretion (GO:2000484)4.62593727
21maternal placenta development (GO:0001893)4.56602975
22negative regulation of execution phase of apoptosis (GO:1900118)4.52824129
23positive regulation of B cell differentiation (GO:0045579)4.24759136
24regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)4.21995218
25sleep (GO:0030431)4.19323623
26positive regulation of mast cell degranulation (GO:0043306)4.15869380
27positive regulation of mast cell activation involved in immune response (GO:0033008)4.15869380
28biotin metabolic process (GO:0006768)4.15699066
29synapsis (GO:0007129)4.13505072
30DNA methylation involved in gamete generation (GO:0043046)4.13162031
31single strand break repair (GO:0000012)4.10807430
32DNA demethylation (GO:0080111)4.09260099
33meiotic cell cycle (GO:0051321)4.05610633
34regulation of female gonad development (GO:2000194)3.83864253
35DNA dealkylation (GO:0035510)3.83365245
36regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.80138256
37epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.77689916
38aggressive behavior (GO:0002118)3.75269198
39regulation of DNA methylation (GO:0044030)3.68261385
40positive regulation of interleukin-17 production (GO:0032740)3.64537947
41regulation of interleukin-8 secretion (GO:2000482)3.50432144
42positive regulation of mast cell activation (GO:0033005)3.48656401
43pyrimidine nucleoside catabolic process (GO:0046135)3.47089638
44regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)3.45562495
45photoreceptor cell maintenance (GO:0045494)3.44971261
46multicellular organism reproduction (GO:0032504)3.44690532
47coenzyme catabolic process (GO:0009109)3.43653864
48retinal cone cell development (GO:0046549)3.37785721
49behavioral response to nicotine (GO:0035095)3.34379290
50positive regulation of chemokine secretion (GO:0090197)3.32538176
51locomotory exploration behavior (GO:0035641)3.31048958
52female gamete generation (GO:0007292)3.24586981
53centriole replication (GO:0007099)3.18767481
54regulation of activated T cell proliferation (GO:0046006)3.18582373
55positive regulation of uterine smooth muscle contraction (GO:0070474)3.13524107
56regulation of isotype switching to IgG isotypes (GO:0048302)3.11458446
57positive regulation of interleukin-1 beta secretion (GO:0050718)3.10287280
58positive regulation of T cell migration (GO:2000406)3.06426486
59chromosome organization involved in meiosis (GO:0070192)3.03107488
60DNA modification (GO:0006304)3.02300802
61positive regulation of antigen processing and presentation (GO:0002579)3.01749595
62histone H2A ubiquitination (GO:0033522)2.99715549
63hyperosmotic salinity response (GO:0042538)2.97335227
64eye photoreceptor cell development (GO:0042462)2.97265287
65positive regulation of histone H3-K4 methylation (GO:0051571)2.96362231
66photoreceptor cell development (GO:0042461)2.93396846
67RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.91448692
68positive regulation of interleukin-1 secretion (GO:0050716)2.90959152
69regulation of acrosome reaction (GO:0060046)2.90357407
70DNA methylation or demethylation (GO:0044728)2.88787956
71regulation of chemokine secretion (GO:0090196)2.88446857
72regulation of interleukin-1 beta secretion (GO:0050706)2.86449683
73relaxation of smooth muscle (GO:0044557)2.85102043
74synaptonemal complex assembly (GO:0007130)2.82808958
75pyrimidine-containing compound catabolic process (GO:0072529)2.81298733
76kidney morphogenesis (GO:0060993)2.81127800
77gene silencing by RNA (GO:0031047)2.78128057
78positive regulation of prostaglandin secretion (GO:0032308)2.77870961
79regulation of histone H3-K9 methylation (GO:0051570)2.75459212
80positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.74650765
81DNA ligation (GO:0006266)2.74222889
82GPI anchor metabolic process (GO:0006505)2.74009012
83synaptonemal complex organization (GO:0070193)2.73209768
84male meiosis (GO:0007140)2.71127478
85positive regulation of B cell mediated immunity (GO:0002714)2.70248693
86positive regulation of immunoglobulin mediated immune response (GO:0002891)2.70248693
87positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.67640110
88positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.67640110
89positive regulation of mitotic sister chromatid separation (GO:1901970)2.67640110
90negative regulation of B cell activation (GO:0050869)2.66815141
91negative regulation of B cell apoptotic process (GO:0002903)2.65384204
92protein targeting to Golgi (GO:0000042)2.63839151
93regulation of female receptivity (GO:0045924)2.61916366
94positive regulation of lymphocyte migration (GO:2000403)2.58680938
95positive regulation of endothelial cell differentiation (GO:0045603)2.57707930
96trophoblast giant cell differentiation (GO:0060707)2.57099354
97regulation of immunoglobulin secretion (GO:0051023)2.55502356
98regulation of prostaglandin secretion (GO:0032306)2.55339310
99centriole assembly (GO:0098534)2.54664340
100positive regulation of DNA recombination (GO:0045911)2.52636373

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.06219708
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.41446286
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.35092265
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.28304442
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.71599616
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.69316082
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.66828909
8ZNF274_21170338_ChIP-Seq_K562_Hela2.37961177
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.35563401
10MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.33831593
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.32735310
12KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.27308266
13KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.27308266
14KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.27308266
15TAF15_26573619_Chip-Seq_HEK293_Human2.18717115
16SMAD_19615063_ChIP-ChIP_OVARY_Human2.16028243
17PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.07955503
18EST1_17652178_ChIP-ChIP_JURKAT_Human2.04769350
19HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.99002439
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.96680630
21NOTCH1_21737748_ChIP-Seq_TLL_Human1.79960792
22STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.77918414
23P300_19829295_ChIP-Seq_ESCs_Human1.75307836
24BP1_19119308_ChIP-ChIP_Hs578T_Human1.69405239
25POU3F2_20337985_ChIP-ChIP_501MEL_Human1.68375852
26EWS_26573619_Chip-Seq_HEK293_Human1.66794440
27VDR_23849224_ChIP-Seq_CD4+_Human1.63016579
28PCGF2_27294783_Chip-Seq_ESCs_Mouse1.61993950
29NANOG_20526341_ChIP-Seq_ESCs_Human1.53363287
30FUS_26573619_Chip-Seq_HEK293_Human1.51749064
31GBX2_23144817_ChIP-Seq_PC3_Human1.49853201
32HTT_18923047_ChIP-ChIP_STHdh_Human1.49098727
33FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.47065348
34FOXA1_21572438_ChIP-Seq_LNCaP_Human1.46047380
35GATA1_22025678_ChIP-Seq_K562_Human1.45414271
36IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.43521174
37NANOG_19829295_ChIP-Seq_ESCs_Human1.42536884
38SOX2_19829295_ChIP-Seq_ESCs_Human1.42536884
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.41345093
40FOXA1_25329375_ChIP-Seq_VCAP_Human1.40067515
41FOXA1_27270436_Chip-Seq_PROSTATE_Human1.40067515
42AR_20517297_ChIP-Seq_VCAP_Human1.38600510
43ELF1_17652178_ChIP-ChIP_JURKAT_Human1.38409151
44FOXP3_21729870_ChIP-Seq_TREG_Human1.37487735
45IRF8_22096565_ChIP-ChIP_GC-B_Human1.34359692
46EZH2_27294783_Chip-Seq_NPCs_Mouse1.34186178
47CTBP1_25329375_ChIP-Seq_LNCAP_Human1.33694604
48ER_23166858_ChIP-Seq_MCF-7_Human1.32838544
49PRDM14_20953172_ChIP-Seq_ESCs_Human1.32048889
50CDX2_22108803_ChIP-Seq_LS180_Human1.29987895
51EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.28863897
52ZFP57_27257070_Chip-Seq_ESCs_Mouse1.28172638
53CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.27862028
54UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27856013
55SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.25146023
56CTBP2_25329375_ChIP-Seq_LNCAP_Human1.24135540
57MYC_18940864_ChIP-ChIP_HL60_Human1.21434587
58NFE2_27457419_Chip-Seq_LIVER_Mouse1.20765329
59MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.20466535
60GATA3_26560356_Chip-Seq_TH2_Human1.19426526
61TCF4_23295773_ChIP-Seq_U87_Human1.18821489
62TOP2B_26459242_ChIP-Seq_MCF-7_Human1.14124609
63SMAD3_21741376_ChIP-Seq_EPCs_Human1.13735995
64PCGF2_27294783_Chip-Seq_NPCs_Mouse1.13187146
65IGF1R_20145208_ChIP-Seq_DFB_Human1.13029928
66TP53_22573176_ChIP-Seq_HFKS_Human1.12792217
67TAL1_26923725_Chip-Seq_HPCs_Mouse1.12699268
68SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12304863
69JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.10902340
70IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10088230
71CBP_20019798_ChIP-Seq_JUKART_Human1.10088230
72BCAT_22108803_ChIP-Seq_LS180_Human1.09980547
73VDR_22108803_ChIP-Seq_LS180_Human1.09957888
74NCOR_22424771_ChIP-Seq_293T_Human1.07876698
75BMI1_23680149_ChIP-Seq_NPCS_Mouse1.06022313
76SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05854913
77TCF4_22108803_ChIP-Seq_LS180_Human1.05458440
78SMRT_27268052_Chip-Seq_Bcells_Human1.04683667
79GATA1_26923725_Chip-Seq_HPCs_Mouse1.04036336
80SMAD4_21741376_ChIP-Seq_EPCs_Human1.04033230
81AUTS2_25519132_ChIP-Seq_293T-REX_Human1.03832075
82RUNX2_22187159_ChIP-Seq_PCA_Human1.03358262
83TP53_16413492_ChIP-PET_HCT116_Human1.02648416
84STAT3_18555785_Chip-Seq_ESCs_Mouse1.02529790
85CRX_20693478_ChIP-Seq_RETINA_Mouse1.01987592
86OCT4_18555785_Chip-Seq_ESCs_Mouse1.01807577
87PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.00953119
88NANOG_18555785_Chip-Seq_ESCs_Mouse1.00386788
89AR_25329375_ChIP-Seq_VCAP_Human1.00265466
90SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.99695734
91TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.98845467
92STAT3_23295773_ChIP-Seq_U87_Human0.98672018
93ELK1_19687146_ChIP-ChIP_HELA_Human0.97672905
94MYC_19829295_ChIP-Seq_ESCs_Human0.97413303
95TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.97310475
96E2F4_17652178_ChIP-ChIP_JURKAT_Human0.96415508
97MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.96335038
98GATA3_21878914_ChIP-Seq_MCF-7_Human0.96279148
99P53_22387025_ChIP-Seq_ESCs_Mouse0.96275242
100TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.95981995

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003718_maternal_effect5.08211221
2MP0006292_abnormal_olfactory_placode3.86003727
3MP0001873_stomach_inflammation3.31433849
4MP0008058_abnormal_DNA_repair2.95781628
5MP0008877_abnormal_DNA_methylation2.73072316
6MP0001853_heart_inflammation2.68804056
7MP0002234_abnormal_pharynx_morphology2.58348112
8MP0008789_abnormal_olfactory_epithelium2.46512335
9MP0005389_reproductive_system_phenotype2.35509989
10MP0002138_abnormal_hepatobiliary_system2.32551916
11MP0001919_abnormal_reproductive_system2.27013697
12MP0005075_abnormal_melanosome_morpholog2.24995515
13MP0000465_gastrointestinal_hemorrhage2.24043974
14MP0000015_abnormal_ear_pigmentation2.21259201
15MP0005174_abnormal_tail_pigmentation2.20493925
16MP0003787_abnormal_imprinting2.13516558
17MP0005360_urolithiasis2.06459501
18MP0005395_other_phenotype2.06050217
19MP0005410_abnormal_fertilization2.00161602
20MP0005646_abnormal_pituitary_gland1.95501164
21MP0002095_abnormal_skin_pigmentation1.91787239
22MP0002139_abnormal_hepatobiliary_system1.89137549
23MP0001835_abnormal_antigen_presentation1.82323364
24MP0003136_yellow_coat_color1.81232679
25MP0005499_abnormal_olfactory_system1.81007393
26MP0005394_taste/olfaction_phenotype1.81007393
27MP0002876_abnormal_thyroid_physiology1.77932407
28MP0001293_anophthalmia1.72649112
29MP0002160_abnormal_reproductive_system1.71391162
30MP0001929_abnormal_gametogenesis1.66349197
31MP0002210_abnormal_sex_determination1.61450462
32MP0002148_abnormal_hypersensitivity_rea1.58648256
33MP0002837_dystrophic_cardiac_calcinosis1.56438674
34MP0005367_renal/urinary_system_phenotyp1.52851385
35MP0000516_abnormal_urinary_system1.52851385
36MP0006082_CNS_inflammation1.40675109
37MP0000653_abnormal_sex_gland1.40018283
38MP0006072_abnormal_retinal_apoptosis1.39826935
39MP0010094_abnormal_chromosome_stability1.33727931
40MP0003693_abnormal_embryo_hatching1.30644357
41MP0002102_abnormal_ear_morphology1.30556498
42MP0000631_abnormal_neuroendocrine_gland1.29337432
43MP0000427_abnormal_hair_cycle1.24900991
44MP0003252_abnormal_bile_duct1.22002288
45MP0005551_abnormal_eye_electrophysiolog1.21006589
46MP0001145_abnormal_male_reproductive1.14755446
47MP0002928_abnormal_bile_duct1.14573842
48MP0001986_abnormal_taste_sensitivity1.14443009
49MP0001324_abnormal_eye_pigmentation1.11995175
50MP0001485_abnormal_pinna_reflex1.11718321
51MP0002638_abnormal_pupillary_reflex1.10967707
52MP0009785_altered_susceptibility_to1.10966872
53MP0008872_abnormal_physiological_respon1.09695840
54MP0003011_delayed_dark_adaptation1.09427408
55MP0005253_abnormal_eye_physiology1.08708694
56MP0003699_abnormal_female_reproductive1.07932188
57MP0005647_abnormal_sex_gland1.07737471
58MP0001984_abnormal_olfaction1.06352565
59MP0004885_abnormal_endolymph1.06201730
60MP0005084_abnormal_gallbladder_morpholo1.05696553
61MP0005671_abnormal_response_to1.05500411
62MP0005645_abnormal_hypothalamus_physiol1.05296924
63MP0002272_abnormal_nervous_system1.03201770
64MP0003786_premature_aging1.01715522
65MP0010368_abnormal_lymphatic_system1.00904380
66MP0001119_abnormal_female_reproductive0.99348626
67MP0001764_abnormal_homeostasis0.99335257
68MP0005085_abnormal_gallbladder_physiolo0.98406147
69MP0003119_abnormal_digestive_system0.97646486
70MP0002938_white_spotting0.96031337
71MP0003656_abnormal_erythrocyte_physiolo0.95515441
72MP0009333_abnormal_splenocyte_physiolog0.95301766
73MP0004742_abnormal_vestibular_system0.92831749
74MP0003698_abnormal_male_reproductive0.90774279
75MP0004147_increased_porphyrin_level0.89823366
76MP0002161_abnormal_fertility/fecundity0.84536308
77MP0006036_abnormal_mitochondrial_physio0.83737666
78MP0003879_abnormal_hair_cell0.81789545
79MP0003195_calcinosis0.79308112
80MP0002736_abnormal_nociception_after0.77595614
81MP0009745_abnormal_behavioral_response0.73477963
82MP0002396_abnormal_hematopoietic_system0.71114995
83MP0003866_abnormal_defecation0.70534007
84MP0001963_abnormal_hearing_physiology0.67258104
85MP0001502_abnormal_circadian_rhythm0.67119758
86MP0002233_abnormal_nose_morphology0.67036042
87MP0001664_abnormal_digestion0.66815513
88MP0008469_abnormal_protein_level0.65456568
89MP0005636_abnormal_mineral_homeostasis0.65454368
90MP0005195_abnormal_posterior_eye0.65350478
91MP0000733_abnormal_muscle_development0.65242154
92MP0009765_abnormal_xenobiotic_induced0.65194393
93MP0001756_abnormal_urination0.65054178
94MP0005310_abnormal_salivary_gland0.64573756
95MP0003300_gastrointestinal_ulcer0.63852750
96MP0001968_abnormal_touch/_nociception0.63329669
97MP0000613_abnormal_salivary_gland0.63219511
98MP0002006_tumorigenesis0.62333146
99MP0001666_abnormal_nutrient_absorption0.61093215
100MP0000604_amyloidosis0.60920651

Predicted human phenotypes

RankGene SetZ-score
1Supernumerary spleens (HP:0009799)4.53188078
2Bile duct proliferation (HP:0001408)4.46345832
3Abnormal biliary tract physiology (HP:0012439)4.46345832
4Abnormality of the renal cortex (HP:0011035)4.09875126
5Abnormality of the prostate (HP:0008775)4.08747137
6Renal cortical cysts (HP:0000803)3.86902976
7Ketoacidosis (HP:0001993)3.64358664
8Pulmonary fibrosis (HP:0002206)3.56930703
9Abnormality of the renal medulla (HP:0100957)3.47581204
10Pancreatic fibrosis (HP:0100732)3.45887037
11Nephronophthisis (HP:0000090)3.41708659
12Aplastic anemia (HP:0001915)3.31214088
13Hypoproteinemia (HP:0003075)3.28569752
14Tachypnea (HP:0002789)3.11191813
15Amaurosis fugax (HP:0100576)2.94035405
16Pancreatic cysts (HP:0001737)2.93378637
17Congenital hepatic fibrosis (HP:0002612)2.81741406
18Abnormality of midbrain morphology (HP:0002418)2.81029496
19Molar tooth sign on MRI (HP:0002419)2.81029496
20Stomatitis (HP:0010280)2.80852240
21Hematochezia (HP:0002573)2.79286914
22Metaphyseal dysplasia (HP:0100255)2.79100731
23Colon cancer (HP:0003003)2.71379328
24Chest pain (HP:0100749)2.71175796
25Gaze-evoked nystagmus (HP:0000640)2.67466053
26Ureteral stenosis (HP:0000071)2.63200269
27Medial flaring of the eyebrow (HP:0010747)2.53682567
28Spontaneous abortion (HP:0005268)2.49485080
29Impulsivity (HP:0100710)2.45626862
30Ketosis (HP:0001946)2.45511049
31Decreased electroretinogram (ERG) amplitude (HP:0000654)2.44271946
32Decreased circulating renin level (HP:0003351)2.42721988
33Ureteral obstruction (HP:0006000)2.42621887
34Hyperglycinemia (HP:0002154)2.41959510
35Hypoplastic iliac wings (HP:0002866)2.40344480
36Aplasia/Hypoplasia of the tongue (HP:0010295)2.39959933
37Severe visual impairment (HP:0001141)2.39198573
38Hypoplasia of the fovea (HP:0007750)2.35852720
39Aplasia/Hypoplasia of the fovea (HP:0008060)2.35852720
40Abnormality of male internal genitalia (HP:0000022)2.34491792
41Short tibia (HP:0005736)2.34183856
42Oral leukoplakia (HP:0002745)2.31156483
43Hyperalaninemia (HP:0003348)2.29319201
44Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.29319201
45Abnormality of alanine metabolism (HP:0010916)2.29319201
46Anhidrosis (HP:0000970)2.28226259
47Abnormality of the phalanges of the 2nd finger (HP:0009541)2.24435098
48Abnormality of the fovea (HP:0000493)2.21309496
49Aplasia/Hypoplasia of the tibia (HP:0005772)2.20402693
50Oligodactyly (hands) (HP:0001180)2.19728521
51Cystic liver disease (HP:0006706)2.19457098
52Hypoalbuminemia (HP:0003073)2.19232347
53Abnormal albumin level (HP:0012116)2.19232347
54Abnormal drinking behavior (HP:0030082)2.17151957
55Polydipsia (HP:0001959)2.17151957
56Posterior subcapsular cataract (HP:0007787)2.16264207
57Progressive external ophthalmoplegia (HP:0000590)2.15683328
58Insulin-resistant diabetes mellitus (HP:0000831)2.13585960
59Dry hair (HP:0011359)2.13016979
60True hermaphroditism (HP:0010459)2.12945737
61Abnormal gallbladder physiology (HP:0012438)2.12131719
62Cholecystitis (HP:0001082)2.12131719
63Septo-optic dysplasia (HP:0100842)2.11450105
64Seborrheic dermatitis (HP:0001051)2.10861009
65IgG deficiency (HP:0004315)2.09989552
66Chronic diarrhea (HP:0002028)2.09483744
67Hypoplastic pelvis (HP:0008839)2.09030207
68Azoospermia (HP:0000027)2.03128327
69Abnormality of the proximal phalanges of the hand (HP:0009834)2.02859453
70Stomach cancer (HP:0012126)2.00862739
71Hyperglycemia (HP:0003074)1.97310466
72Hypophosphatemic rickets (HP:0004912)1.96237357
73Abnormal delayed hypersensitivity skin test (HP:0002963)1.95645623
74Arterial thrombosis (HP:0004420)1.95553310
75Congenital, generalized hypertrichosis (HP:0004540)1.95402555
763-Methylglutaconic aciduria (HP:0003535)1.94206108
77Attenuation of retinal blood vessels (HP:0007843)1.93764083
78Entropion (HP:0000621)1.93718447
79Tubulointerstitial fibrosis (HP:0005576)1.92727713
80Reduced subcutaneous adipose tissue (HP:0003758)1.91471762
81Autoimmune hemolytic anemia (HP:0001890)1.90185443
82Gonadotropin excess (HP:0000837)1.89157625
83Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.88689526
84Neoplasm of the adrenal cortex (HP:0100641)1.87576471
85Abnormality of the heme biosynthetic pathway (HP:0010472)1.86469945
86Abnormal tarsal ossification (HP:0008369)1.80824251
87Sensory axonal neuropathy (HP:0003390)1.80711277
88Median cleft lip (HP:0000161)1.78575028
89Polyuria (HP:0000103)1.77503398
90Abolished electroretinogram (ERG) (HP:0000550)1.75933706
91Erythroderma (HP:0001019)1.74556577
92Degeneration of the lateral corticospinal tracts (HP:0002314)1.74550245
93Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.74550245
94Asplenia (HP:0001746)1.74531024
95Abnormal auditory evoked potentials (HP:0006958)1.74187314
96Adrenal hypoplasia (HP:0000835)1.72551072
97Abnormality of abdominal situs (HP:0011620)1.72322640
98Abdominal situs inversus (HP:0003363)1.72322640
99Pancytopenia (HP:0001876)1.71880354
100Abnormality of B cell number (HP:0010975)1.71425274

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK6.60973855
2TAOK35.29829092
3MAP3K134.48197778
4BMPR1B4.17473703
5MAP4K23.66825683
6FRK3.22577448
7NUAK12.93469368
8MST42.49596725
9CSNK1G32.13085762
10CSNK1G22.00016911
11CSNK1A1L1.86075676
12CSNK1G11.82400792
13WNK31.67972774
14VRK21.63618239
15ZAK1.58070111
16CDK91.51622844
17IKBKB1.35194464
18MAP2K71.35161993
19PIK3CA1.34567962
20NEK11.34097885
21GRK11.30341633
22VRK11.19913737
23CDK191.18029198
24ADRBK21.16776571
25MAP3K141.16440586
26ARAF1.12282276
27OXSR11.12013615
28TLK11.05480060
29KDR1.04736563
30PIM21.03007981
31CHUK1.01842431
32NEK60.97582578
33TAF10.95006689
34AURKA0.91431050
35MAP3K70.89310867
36EIF2AK30.86855958
37TNK20.83584963
38FES0.83490880
39MAPKAPK30.80951367
40NTRK20.80694238
41STK390.79462336
42ITK0.76238142
43TYRO30.74222847
44PLK30.74072794
45MAP3K90.72886547
46CSNK1D0.71538237
47BMPR20.70284682
48TNIK0.69881460
49TRIM280.69706548
50WNK40.68364584
51BRSK20.67742068
52PIM10.65666706
53BCKDK0.65392377
54TIE10.63782936
55PLK20.62870740
56INSRR0.62234258
57PINK10.61961617
58GRK50.61642534
59TTK0.59236714
60PRKCQ0.58000165
61STK240.57947240
62MAPKAPK50.57800092
63RAF10.57279452
64PRKCI0.55180150
65EPHA40.52688630
66TGFBR10.52131206
67BRAF0.51051455
68CSK0.49112407
69PRKCE0.47143638
70MET0.46355869
71CSNK1A10.45893168
72TEC0.45317853
73PRKG10.44655147
74PLK10.44213786
75CHEK20.44077190
76ATM0.43497422
77CDC70.41210284
78ACVR1B0.40459417
79FGFR20.39412599
80EIF2AK20.38200953
81PRKACA0.37173709
82NEK20.36978296
83CAMK2A0.35334483
84PRKCG0.34030458
85ATR0.31936377
86CSNK2A20.31883225
87STK30.31431080
88ERBB30.30027758
89RPS6KA50.29793796
90TRPM70.29390585
91IGF1R0.28633710
92MOS0.27589333
93PRKAA20.27450185
94LCK0.27207481
95OBSCN0.26030409
96DYRK20.25335319
97MAPK30.25147701
98PRKACB0.25038907
99PTK2B0.23655387
100CDK70.22454499

Predicted pathways (KEGG)

RankGene SetZ-score
1Autoimmune thyroid disease_Homo sapiens_hsa053204.07672928
2Asthma_Homo sapiens_hsa053104.02837183
3Basal transcription factors_Homo sapiens_hsa030223.24171874
4Allograft rejection_Homo sapiens_hsa053303.09405766
5Graft-versus-host disease_Homo sapiens_hsa053322.90038767
6Vitamin digestion and absorption_Homo sapiens_hsa049772.67845886
7Type I diabetes mellitus_Homo sapiens_hsa049402.57626221
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.48965590
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.24325533
10Phototransduction_Homo sapiens_hsa047442.14606546
11Proteasome_Homo sapiens_hsa030502.02458004
12Maturity onset diabetes of the young_Homo sapiens_hsa049501.96235744
13Non-homologous end-joining_Homo sapiens_hsa034501.95848134
14Homologous recombination_Homo sapiens_hsa034401.94506843
15RNA degradation_Homo sapiens_hsa030181.85644159
16Rheumatoid arthritis_Homo sapiens_hsa053231.84743261
17Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.84575237
18Primary immunodeficiency_Homo sapiens_hsa053401.81339149
19Caffeine metabolism_Homo sapiens_hsa002321.78329774
20Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.78117039
21Circadian rhythm_Homo sapiens_hsa047101.76017161
22Nucleotide excision repair_Homo sapiens_hsa034201.73660761
23Intestinal immune network for IgA production_Homo sapiens_hsa046721.72893522
24RNA polymerase_Homo sapiens_hsa030201.67483073
25Oxidative phosphorylation_Homo sapiens_hsa001901.64300316
26NOD-like receptor signaling pathway_Homo sapiens_hsa046211.52605255
27Olfactory transduction_Homo sapiens_hsa047401.47494479
28Ovarian steroidogenesis_Homo sapiens_hsa049131.39025653
29Hematopoietic cell lineage_Homo sapiens_hsa046401.36748131
30Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.32484188
31Fanconi anemia pathway_Homo sapiens_hsa034601.24596767
32Dorso-ventral axis formation_Homo sapiens_hsa043201.21130012
33T cell receptor signaling pathway_Homo sapiens_hsa046601.19514932
34Parkinsons disease_Homo sapiens_hsa050121.15929736
35Peroxisome_Homo sapiens_hsa041461.14307236
36Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.13019872
37Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.09683345
38Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.09171457
39Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.07214053
40Protein export_Homo sapiens_hsa030601.04548990
41Oocyte meiosis_Homo sapiens_hsa041141.02100042
42Ribosome_Homo sapiens_hsa030100.95880582
43Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.92117126
44Mismatch repair_Homo sapiens_hsa034300.90100823
45Propanoate metabolism_Homo sapiens_hsa006400.87255882
46p53 signaling pathway_Homo sapiens_hsa041150.85192990
47Sphingolipid metabolism_Homo sapiens_hsa006000.85191902
48Antigen processing and presentation_Homo sapiens_hsa046120.84665180
49Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.80970424
50RNA transport_Homo sapiens_hsa030130.80904717
51Nicotine addiction_Homo sapiens_hsa050330.76570728
52Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74008225
53ABC transporters_Homo sapiens_hsa020100.72539899
54Huntingtons disease_Homo sapiens_hsa050160.72188006
55Linoleic acid metabolism_Homo sapiens_hsa005910.71855508
56Base excision repair_Homo sapiens_hsa034100.70458674
57Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.70140804
58Cysteine and methionine metabolism_Homo sapiens_hsa002700.69645912
59Retinol metabolism_Homo sapiens_hsa008300.66884204
60SNARE interactions in vesicular transport_Homo sapiens_hsa041300.66276188
61Selenocompound metabolism_Homo sapiens_hsa004500.65428363
62Alzheimers disease_Homo sapiens_hsa050100.64221151
63Chemical carcinogenesis_Homo sapiens_hsa052040.63508286
64Cell cycle_Homo sapiens_hsa041100.63409574
65Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.62551857
66Purine metabolism_Homo sapiens_hsa002300.62053248
67Arachidonic acid metabolism_Homo sapiens_hsa005900.60686541
68Ether lipid metabolism_Homo sapiens_hsa005650.59259200
69Pyrimidine metabolism_Homo sapiens_hsa002400.56811283
70Salivary secretion_Homo sapiens_hsa049700.54824472
71Measles_Homo sapiens_hsa051620.53393744
72Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.53140055
73Hedgehog signaling pathway_Homo sapiens_hsa043400.52811052
74Nitrogen metabolism_Homo sapiens_hsa009100.52185048
75Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.51654236
76RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.50690253
77Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.49891807
78Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48725109
79Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45108635
80Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44829748
81Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.43441325
82Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.42084952
83Collecting duct acid secretion_Homo sapiens_hsa049660.41573745
84Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.40542917
85Taste transduction_Homo sapiens_hsa047420.39778141
86Steroid hormone biosynthesis_Homo sapiens_hsa001400.39330081
87Metabolic pathways_Homo sapiens_hsa011000.38811376
88Transcriptional misregulation in cancer_Homo sapiens_hsa052020.36098962
89Systemic lupus erythematosus_Homo sapiens_hsa053220.35691622
90Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.31536775
91Butanoate metabolism_Homo sapiens_hsa006500.30391523
92Cardiac muscle contraction_Homo sapiens_hsa042600.27763559
93Jak-STAT signaling pathway_Homo sapiens_hsa046300.23702881
94One carbon pool by folate_Homo sapiens_hsa006700.21775554
95Glycosaminoglycan degradation_Homo sapiens_hsa005310.21526288
96Tyrosine metabolism_Homo sapiens_hsa003500.18741069
97Herpes simplex infection_Homo sapiens_hsa051680.18720258
98NF-kappa B signaling pathway_Homo sapiens_hsa040640.18403277
99Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.18288776
100alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.18048801

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »